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Metabolism: clinical and experimental最新文献

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Relacorilant Improved Blood Pressure and Maintained Other Cardiometabolic Improvements in Long-term Study in Patients With Endogenous Hypercortisolism (Cushing Syndrome) 内源性高皮质醇血症（库欣综合征）患者的长期研究中抗凝性改善血压和维持其他心脏代谢改善
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156213
Richard J. Auchus , Aleksandra Gilis-Januszewska , Corin Badiu , Aurelian-Emil Ranetti , Alexandra Kautzky-Willer , Rosario Pivonello , Georgiana Dobri , Harold J. Miller , Dan Niculescu , Amer Al-Karadsheh , Carmen Aresta , Iulia Cristina Tudor , Hristina Pashova , Katherine Araque , Andreas Moraitis
{"title":"Relacorilant Improved Blood Pressure and Maintained Other Cardiometabolic Improvements in Long-term Study in Patients With Endogenous Hypercortisolism (Cushing Syndrome)","authors":"Richard J. Auchus , Aleksandra Gilis-Januszewska , Corin Badiu , Aurelian-Emil Ranetti , Alexandra Kautzky-Willer , Rosario Pivonello , Georgiana Dobri , Harold J. Miller , Dan Niculescu , Amer Al-Karadsheh , Carmen Aresta , Iulia Cristina Tudor , Hristina Pashova , Katherine Araque , Andreas Moraitis","doi":"10.1016/j.metabol.2025.156213","DOIUrl":"10.1016/j.metabol.2025.156213","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156213"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The pan-PPAR Agonist Lanifibranor Improves Liver Inflammation, Ballooning, and Fibrosis in a Diet-induced Obese MASH Hamster Model of Binge Drinking 泛ppar激动剂lanifbranor改善饮食诱导的狂饮肥胖仓鼠模型中的肝脏炎症、水肿和纤维化
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156202
François Briand, Estelle Grasset, Claire Bigot, Natalia Breyner, Thierry Sulpice
{"title":"The pan-PPAR Agonist Lanifibranor Improves Liver Inflammation, Ballooning, and Fibrosis in a Diet-induced Obese MASH Hamster Model of Binge Drinking","authors":"François Briand, Estelle Grasset, Claire Bigot, Natalia Breyner, Thierry Sulpice","doi":"10.1016/j.metabol.2025.156202","DOIUrl":"10.1016/j.metabol.2025.156202","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156202"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between Markers of Adiposity and Cardiovascular and Renal Outcomes in Patients with Type 2 Diabetes 2型糖尿病患者肥胖标志物与心血管和肾脏预后之间的关系
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156228
Themis Zelmanovitz, Danie Weber, Cristina Pavinatto, Gabriela Bello, Pietro Perufo, Marina L. Harthmann, Rogerio Bender Junior, Isabella Passos, Sofia Simoni, Sandra Silveiro
{"title":"Association Between Markers of Adiposity and Cardiovascular and Renal Outcomes in Patients with Type 2 Diabetes","authors":"Themis Zelmanovitz, Danie Weber, Cristina Pavinatto, Gabriela Bello, Pietro Perufo, Marina L. Harthmann, Rogerio Bender Junior, Isabella Passos, Sofia Simoni, Sandra Silveiro","doi":"10.1016/j.metabol.2025.156228","DOIUrl":"10.1016/j.metabol.2025.156228","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156228"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Continuous Glucose Monitoring Metrics Predict All-cause Mortality in Patients with Both Type 1 and Type 2 Diabetes Running title: CGM Metrics and All-cause Mortality 连续血糖监测指标预测1型和2型糖尿病患者的全因死亡率
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156223
Tomoki Okuno , Sharon A. Macwan , Gregory J. Norman , Donald R. Miller , Peter D. Reaven , Jin J. Zhou
{"title":"Continuous Glucose Monitoring Metrics Predict All-cause Mortality in Patients with Both Type 1 and Type 2 Diabetes Running title: CGM Metrics and All-cause Mortality","authors":"Tomoki Okuno , Sharon A. Macwan , Gregory J. Norman , Donald R. Miller , Peter D. Reaven , Jin J. Zhou","doi":"10.1016/j.metabol.2025.156223","DOIUrl":"10.1016/j.metabol.2025.156223","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156223"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects Of Late Onset Estradiol Treatment On Insulin Resistance And Lipid Metabolism In High-Fat-Fed Ovariectomized Female Mice 晚发性雌二醇治疗对高脂喂养去卵巢雌性小鼠胰岛素抵抗和脂质代谢的影响
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156205
A.G. Cruz, J.D.M. Santos, B.M.F. Trinca, A.R.M. Santos, J.P. Camporez
{"title":"Effects Of Late Onset Estradiol Treatment On Insulin Resistance And Lipid Metabolism In High-Fat-Fed Ovariectomized Female Mice","authors":"A.G. Cruz, J.D.M. Santos, B.M.F. Trinca, A.R.M. Santos, J.P. Camporez","doi":"10.1016/j.metabol.2025.156205","DOIUrl":"10.1016/j.metabol.2025.156205","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156205"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cumulative Effects of Vicadrostat (BI 690517) and Empagliflozin on Albuminuria in People with Chronic Kidney Disease Vicadrostat （BI 690517）和恩格列净对慢性肾病患者蛋白尿的累积效应
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156218
Peter Rossing , Sibylle J. Hauske , Lisa Cronin , Hiddo J.L. Heerspink , Juliane Meyerhoff , Shimoli V. Shah , Zhichao Sun , Dick de Zeeuw , Katherine R. Tuttle , on behalf of the ASi in CKD group
{"title":"Cumulative Effects of Vicadrostat (BI 690517) and Empagliflozin on Albuminuria in People with Chronic Kidney Disease","authors":"Peter Rossing , Sibylle J. Hauske , Lisa Cronin , Hiddo J.L. Heerspink , Juliane Meyerhoff , Shimoli V. Shah , Zhichao Sun , Dick de Zeeuw , Katherine R. Tuttle , on behalf of the ASi in CKD group","doi":"10.1016/j.metabol.2025.156218","DOIUrl":"10.1016/j.metabol.2025.156218","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156218"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Circadian-timed Cycloset Therapy Reduces Cardiovascular Event Rate in Type 2 Diabetes (T2DM) Subjects with Clinical Features Suggestive of Elevated Sympathetic Nervous System Activity – Pilot Study Results 以昼夜节律为时间周期的周期疗法可降低伴有交感神经系统活动升高的2型糖尿病（T2DM）患者的心血管事件发生率——初步研究结果
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156224
Bindu Chamarthi, Michael Ezrokhi, Carl Stoelzel, Anthony H. Cincotta
{"title":"Circadian-timed Cycloset Therapy Reduces Cardiovascular Event Rate in Type 2 Diabetes (T2DM) Subjects with Clinical Features Suggestive of Elevated Sympathetic Nervous System Activity – Pilot Study Results","authors":"Bindu Chamarthi, Michael Ezrokhi, Carl Stoelzel, Anthony H. Cincotta","doi":"10.1016/j.metabol.2025.156224","DOIUrl":"10.1016/j.metabol.2025.156224","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156224"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics of Diabetes Patients with Inadequately Controlled Hypertension: Insights from the EnligHTN Study 高血压控制不充分的糖尿病患者的特征：来自EnligHTN研究的见解
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156219
Vivek Bhalla , Samuel Adamsson Eryd , Tom Norris , Maghan Ballantyne , Terry McCormack
{"title":"Characteristics of Diabetes Patients with Inadequately Controlled Hypertension: Insights from the EnligHTN Study","authors":"Vivek Bhalla , Samuel Adamsson Eryd , Tom Norris , Maghan Ballantyne , Terry McCormack","doi":"10.1016/j.metabol.2025.156219","DOIUrl":"10.1016/j.metabol.2025.156219","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156219"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility and Safety of Novel Endoscopic Ultrasound-Guided Delivery of Human GLP-1 Pancreatic Gene Therapy in Pigs 新型超声内镜下给药人胰源性磷脂-1基因治疗猪的可行性和安全性
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156232
Timothy Kieffer , Chris Thompson , Jake Wainer , Michael Biasella , Lindsay Schulman , Nicole Picard , Rebecca Reese , Alice Liou Fitzpatrick , Edward Mahoney , Emily Cozzi , Shimyn Slomovic , Jay Caplan , Harith Rajagopalan
{"title":"Feasibility and Safety of Novel Endoscopic Ultrasound-Guided Delivery of Human GLP-1 Pancreatic Gene Therapy in Pigs","authors":"Timothy Kieffer , Chris Thompson , Jake Wainer , Michael Biasella , Lindsay Schulman , Nicole Picard , Rebecca Reese , Alice Liou Fitzpatrick , Edward Mahoney , Emily Cozzi , Shimyn Slomovic , Jay Caplan , Harith Rajagopalan","doi":"10.1016/j.metabol.2025.156232","DOIUrl":"10.1016/j.metabol.2025.156232","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156232"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combination of Icovamenib and GLP-1-based Therapeutic Agents Improves Beta Cell Function and Insulin Secretion 依维美尼联合glp -1治疗药物改善β细胞功能和胰岛素分泌
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156226
Mini Balakrishnan, Tracy Zhang, Kung-Hsien Ho, Dina Mousavi, Juan Pablo Frias, Thomas Butler
{"title":"Combination of Icovamenib and GLP-1-based Therapeutic Agents Improves Beta Cell Function and Insulin Secretion","authors":"Mini Balakrishnan, Tracy Zhang, Kung-Hsien Ho, Dina Mousavi, Juan Pablo Frias, Thomas Butler","doi":"10.1016/j.metabol.2025.156226","DOIUrl":"10.1016/j.metabol.2025.156226","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156226"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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