Mini-reviews in Organic Chemistry最新文献_第2页

An Overview of Diverse Biological Activities of Cinnoline Scaffold 噌啉支架的多种生物活性概述

IF 2.3 4区化学

Mini-reviews in Organic Chemistry Pub Date : 2024-02-02 DOI: 10.2174/0118756298265037231119063008

Mohammad Asif, Mamdouh Allahyani, Abdulelah Aljuaid, Mazen M. Almehmadi, Ahad Alsaiari, Abdulaziz Alsharif

引用次数: 0

Neuropharmacological Potential of Different Piperazine Analogs: A Recent Prospective 不同哌嗪类似物的神经药理潜力：最近的一项前瞻性研究

IF 2.3 4区化学

Mini-reviews in Organic Chemistry Pub Date : 2024-02-02 DOI: 10.2174/0118756298277743231213065544

Mamdouh Allahyani, Mazen Almehmadi, Ahad Amer Alsaiari, Mohammad Asif, Sachin Kumar

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Advances in Chemical Epigenetic Modification Methods in the Study of Fungal Secondary Metabolites 研究真菌次级代谢物的化学表观遗传修饰方法的进展

IF 2.3 4区化学

Mini-reviews in Organic Chemistry Pub Date : 2024-02-02 DOI: 10.2174/0118756298278037231122041718

Bing Liu, Yuxin Wang, Ning Chen, Chenxue Li, Jintong Zhao, Ting Li

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Last Decades’ Overview on Tandem Catalysis: Intrigue in Organo-metallic Chemistry 过去几十年串联催化概述：有机金属化学的奥秘

IF 2.3 4区化学

Mini-reviews in Organic Chemistry Pub Date : 2024-02-01 DOI: 10.2174/0118756298288651240103062430

Jyoti Kuchhadiya, khushal kapadiya

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Electrosynthesis of Sugar Derivatives 糖衍生物的电合成

IF 2.3 4区化学

Mini-reviews in Organic Chemistry Pub Date : 2024-02-01 DOI: 10.2174/0118756298267514240104101246

Cintia Santiago, Natividad Bejarano Rengel, Pablo Fernández, Agustin Ponzinibbio

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A Systematic Review of Electrochemical Sensing Devices Based on Metal-organic Frameworks for the Identification of Tumor Biomarkers 基于金属有机框架的电化学传感设备用于鉴定肿瘤生物标记物的系统综述

IF 2.3 4区化学

Mini-reviews in Organic Chemistry Pub Date : 2024-02-01 DOI: 10.2174/0118756298276294231130111658

Aiany Maria Queiroz Felix, Karen Loraine Macena Santos, Severino Alves Júnior, Maria Danielly Lima Oliveira, César Augusto Souza de Andrade

{"title":"A Systematic Review of Electrochemical Sensing Devices Based on Metal-organic Frameworks for the Identification of Tumor Biomarkers","authors":"Aiany Maria Queiroz Felix, Karen Loraine Macena Santos, Severino Alves Júnior, Maria Danielly Lima Oliveira, César Augusto Souza de Andrade","doi":"10.2174/0118756298276294231130111658","DOIUrl":"https://doi.org/10.2174/0118756298276294231130111658","url":null,"abstract":"Background:: Electrochemical sensors have attracted enormous interest in recent decades due to their relatively simple synthesis process, the possibility of modifications in their composition, and their wide application in detecting analytes. Method:: To achieve excellent performance, materials used in its construction must facilitate the transfer of electrons and provide a large surface area and excellent electrocatalytic activity. Because they are functional nanomaterials, metal-organic frameworks (MOFs) meet the criteria for application as a sensing material and can be used to build high-performance sensors for numerous applications. They play a relevant role in the early diagnosis of various neoplasms and tumor processes, thus providing better prognoses. Considering this universe, the present study focused on evaluating the application of these nanomaterials in the recognition of tumor biomarkers. Result:: A systematic review of scientific publications was performed using the following descriptors \"MOFs\", \"Metal-organic frameworks\", \"Biosensor\", \"Electrochemistry\", and \"Tumor Biomarker\". Conclusion:: Herein, we analyze recent innovations of MOF-based biosensors applied to the detection of tumor biomarkers, discussing how promising characteristics and properties of these materials were harnessed in the development of biosensors to provide a new contribution to future studies and the development of applied MOFs to electrochemical biosensing.","PeriodicalId":18632,"journal":{"name":"Mini-reviews in Organic Chemistry","volume":"43 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139667406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Attractive and Comprehensive Review on C-O Bond Formation: Nanomagnetic Recoverable Catalysts to Access Diaryl Ethers via C-O Cross-coupling Reactions 关于 C-O 键形成的极具吸引力的全面综述：通过 C-O 交叉偶联反应获得二芳基醚的纳米磁性可回收催化剂

IF 2.3 4区化学

Mini-reviews in Organic Chemistry Pub Date : 2024-01-25 DOI: 10.2174/0118756298281758231201052421

Marim Alwan, Shaymaa Abed Hussein, Usama S. Altimari, Mustafa Humam Sami, Ashour H. Dawood, Benien M. Ridha, Ali H. Alsalamy, Mosstafa Kazemi

{"title":"An Attractive and Comprehensive Review on C-O Bond Formation: Nanomagnetic Recoverable Catalysts to Access Diaryl Ethers via C-O Cross-coupling Reactions","authors":"Marim Alwan, Shaymaa Abed Hussein, Usama S. Altimari, Mustafa Humam Sami, Ashour H. Dawood, Benien M. Ridha, Ali H. Alsalamy, Mosstafa Kazemi","doi":"10.2174/0118756298281758231201052421","DOIUrl":"https://doi.org/10.2174/0118756298281758231201052421","url":null,"abstract":": The simple separation of magnetic nanocatalysts from the reaction mixture using only an external magnet caused a huge revolution in catalysis, particularly in organic synthesis. Diaryl ethers (compounds containing (Ar-O-Ar linkages) are one of the most important and prominent compounds and are widely found in natural products and pharmaceutical and biological molecules. The C-O cross-coupling or O-arylation reactions of aryl halides with aromatic alcohols, especially phenols, is an important and straightforward strategy for the preparation of diaryl ethers. Due to the high importance of diaryl ethers in the pharmaceutical, chemical and medical fields, many efforts have been made for the synthesis of diaryl ethers through C-O cross-coupling aryl halides with aromatic alcohols, especially phenols based on using non-magnetic reusable catalysts. In this review, we carefully reviewed the synthesis of diaryl ethers and discussed the reaction conditions and product yields in each method.","PeriodicalId":18632,"journal":{"name":"Mini-reviews in Organic Chemistry","volume":"124 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139579884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biological Activities of Aurones: A Brief Summary Aurones 的生物活性：简述

IF 2.3 4区化学

Mini-reviews in Organic Chemistry Pub Date : 2024-01-11 DOI: 10.2174/0118756298277226231128032502

Qiang Zhu, Xing Zheng, Yan Tan, Zhongqin Luo, Xu Yao, Hongfei Chen

{"title":"Biological Activities of Aurones: A Brief Summary","authors":"Qiang Zhu, Xing Zheng, Yan Tan, Zhongqin Luo, Xu Yao, Hongfei Chen","doi":"10.2174/0118756298277226231128032502","DOIUrl":"https://doi.org/10.2174/0118756298277226231128032502","url":null,"abstract":": Aurones are structural isomers of flavones and flavonols with the basic C6–C3–C6 skeleton arranged as (Z)-2-benzylidenebenzofuran-3(2H)-one, which contain an exocyclic carbon-carbon double bond bridging the benzofuranone and phenyl rings. In aurone, a chalcone-like group is closed into a 5-membered ring instead of the 6-membered ring more typical of flavonoids, which forms the core for a family of derivatives that are known collectively as aurones. As a kind of flavonoids, aurones are widely distributed in many plants which provide yellow color to some popular ornamental flowers. For a long time aurones had not got enough attention, while in recent years, finally this chemical is coming into researchers' view. As the secondary metabolite in the family of flavonoids, aurones displayed various biological activities, including antioxidant, antiparasitic, antitumor, antiviral, antibacterial, anti-inflammatory, anti-SARS-CoV-2 and neuropharmacological activities. Therefore, aurones have attracted the attention of more and more chemists and pharmaceutical chemists, who realized that it is possible to get lead compounds with better activities via structural modifications of aurones. In some research works, aurone and its derivatives have exhibited good activity, e.g., Xie discovered the heterocyclic variant of the (Z)-2-benzylidene-6-hydroxybenzofuran-3(2H)- one scaffold that possessed low nanomolar in vitro potency in cell proliferation assays using various cancer cell lines, in vivo potency in prostate cancer PC-3 xenograft and zebrafish models, and absence of appreciable toxicity, which proved that aurones are valuable compounds worthy of further study. Herein, the biological activities of aurone derivatives are reviewed, which covers the literature since 2000, in which the strategies to develop bioactive aurone derivatives and the structureactivity relationship are highlighted.","PeriodicalId":18632,"journal":{"name":"Mini-reviews in Organic Chemistry","volume":"122 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139459482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis, Reactions and Biological Activity of Pyrimido [5, 4-c] Quinolines based on (Thio)Barbituric Acid and their Analogous (Part IV) 基于（硫代）巴比妥酸及其类似物的嘧啶并[5，4-c]喹啉的合成、反应和生物活性（第四部分）

IF 2.3 4区化学

Mini-reviews in Organic Chemistry Pub Date : 2024-01-11 DOI: 10.2174/0118756298276728231130042823

Ameen Abu-Hashem, Taha Ameen, Emad El-Telbani, Hoda A.R. Hussein, Moustafa Gouda

{"title":"Synthesis, Reactions and Biological Activity of Pyrimido [5, 4-c] Quinolines based on (Thio)Barbituric Acid and their Analogous (Part IV)","authors":"Ameen Abu-Hashem, Taha Ameen, Emad El-Telbani, Hoda A.R. Hussein, Moustafa Gouda","doi":"10.2174/0118756298276728231130042823","DOIUrl":"https://doi.org/10.2174/0118756298276728231130042823","url":null,"abstract":": Pyrimido [5, 4-c] quinolone derivatives are significant synthetic targets that show numerous interesting biological activities. The pyrimido [4, 5-b] quinoline is the most famous source of these derivatives, which has been used in medicine to antitumor and target different diseases. Since the segregation of quinoline derivatives, many synthetic methodologies were advanced for their synthesis. Despite the current interesting findings on this class of pyrimidoquinoline, the chemical literature deficits a comprehensive summary of the synthetic methodologies and biological activities of pyrimido [5, 4-c] quinoline derivatives. This review focuses on recent advances in pyrimido [5, 4-c] quinolines chemistry via debating diverse synthetic ways developed for the preparation of pyrimido [5, 4-c] quinolines and other unique derivatives that exhibited promising biological activities. Also, it sheds light on the most widespread reactions of pyrimidoquinolines and the employment of these derivatives as the essential building blocks for different biologically active compounds:. Among these reactions used to prepare pyrimido [5, 4-c] quinoline derivatives are the following: Biginelli-type one or three-component reaction, Micheal addition, intermolecular cyclization, cyclo-condensation, acylation, Vielsmeir formylation, Suzuki cross-coupling reaction, transformation, oxidation-reduction, esterification, dehydration, decarboxylation, methylation, chlorination, alkylation.","PeriodicalId":18632,"journal":{"name":"Mini-reviews in Organic Chemistry","volume":"5 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139459442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Review on the Role of Sea Salt in Food and its Applications for Human Health 海盐在食品中的作用及其对人类健康的应用综述

IF 2.3 4区化学

Mini-reviews in Organic Chemistry Pub Date : 2024-01-11 DOI: 10.2174/0118756298273343231128062213

Thi-Kien Dao, Trong-The Nguyen, Ngoc-Thanh Vu

引用次数: 0