Aiany Maria Queiroz Felix, Karen Loraine Macena Santos, Severino Alves Júnior, Maria Danielly Lima Oliveira, César Augusto Souza de Andrade
{"title":"A Systematic Review of Electrochemical Sensing Devices Based on Metal-organic Frameworks for the Identification of Tumor Biomarkers","authors":"Aiany Maria Queiroz Felix, Karen Loraine Macena Santos, Severino Alves Júnior, Maria Danielly Lima Oliveira, César Augusto Souza de Andrade","doi":"10.2174/0118756298276294231130111658","DOIUrl":null,"url":null,"abstract":"Background:: Electrochemical sensors have attracted enormous interest in recent decades due to their relatively simple synthesis process, the possibility of modifications in their composition, and their wide application in detecting analytes. Method:: To achieve excellent performance, materials used in its construction must facilitate the transfer of electrons and provide a large surface area and excellent electrocatalytic activity. Because they are functional nanomaterials, metal-organic frameworks (MOFs) meet the criteria for application as a sensing material and can be used to build high-performance sensors for numerous applications. They play a relevant role in the early diagnosis of various neoplasms and tumor processes, thus providing better prognoses. Considering this universe, the present study focused on evaluating the application of these nanomaterials in the recognition of tumor biomarkers. Result:: A systematic review of scientific publications was performed using the following descriptors \"MOFs\", \"Metal-organic frameworks\", \"Biosensor\", \"Electrochemistry\", and \"Tumor Biomarker\". Conclusion:: Herein, we analyze recent innovations of MOF-based biosensors applied to the detection of tumor biomarkers, discussing how promising characteristics and properties of these materials were harnessed in the development of biosensors to provide a new contribution to future studies and the development of applied MOFs to electrochemical biosensing.","PeriodicalId":18632,"journal":{"name":"Mini-reviews in Organic Chemistry","volume":null,"pages":null},"PeriodicalIF":1.9000,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Mini-reviews in Organic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.2174/0118756298276294231130111658","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
Background:: Electrochemical sensors have attracted enormous interest in recent decades due to their relatively simple synthesis process, the possibility of modifications in their composition, and their wide application in detecting analytes. Method:: To achieve excellent performance, materials used in its construction must facilitate the transfer of electrons and provide a large surface area and excellent electrocatalytic activity. Because they are functional nanomaterials, metal-organic frameworks (MOFs) meet the criteria for application as a sensing material and can be used to build high-performance sensors for numerous applications. They play a relevant role in the early diagnosis of various neoplasms and tumor processes, thus providing better prognoses. Considering this universe, the present study focused on evaluating the application of these nanomaterials in the recognition of tumor biomarkers. Result:: A systematic review of scientific publications was performed using the following descriptors "MOFs", "Metal-organic frameworks", "Biosensor", "Electrochemistry", and "Tumor Biomarker". Conclusion:: Herein, we analyze recent innovations of MOF-based biosensors applied to the detection of tumor biomarkers, discussing how promising characteristics and properties of these materials were harnessed in the development of biosensors to provide a new contribution to future studies and the development of applied MOFs to electrochemical biosensing.
期刊介绍:
Mini-Reviews in Organic Chemistry is a peer reviewed journal which publishes original reviews on all areas of organic chemistry including organic synthesis, bioorganic and medicinal chemistry, natural product chemistry, molecular recognition, and physical organic chemistry. The emphasis will be on publishing quality papers very rapidly, without any charges.
The journal encourages submission of reviews on emerging fields of organic chemistry including:
Bioorganic Chemistry
Carbohydrate Chemistry
Chemical Biology
Chemical Process Research
Computational Organic Chemistry
Development of Synthetic Methodologies
Functional Organic Materials
Heterocyclic Chemistry
Macromolecular Chemistry
Natural Products Isolation And Synthesis
New Synthetic Methodology
Organic Reactions
Organocatalysis
Organometallic Chemistry
Theoretical Organic Chemistry
Polymer Chemistry
Stereochemistry
Structural Investigations
Supramolecular Chemistry