Journal of Biophotonics最新文献_第9页

Noncontact Diffuse Reflectance Spectroscopy of Synovial Fluid Samples for Rapid Identification of Infections 用于快速鉴定感染的滑膜液样本非接触式漫反射光谱仪

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-09-04 DOI: 10.1002/jbio.202400213

Erin E. Drewke, Robert L. Brand, Caroline G. Geels, Hanna K. Jensen, Kevin Wong, Jarret D. Sanders, Narasimhan Rajaram

{"title":"Noncontact Diffuse Reflectance Spectroscopy of Synovial Fluid Samples for Rapid Identification of Infections","authors":"Erin E. Drewke, Robert L. Brand, Caroline G. Geels, Hanna K. Jensen, Kevin Wong, Jarret D. Sanders, Narasimhan Rajaram","doi":"10.1002/jbio.202400213","DOIUrl":"10.1002/jbio.202400213","url":null,"abstract":"<p>Severe joint infections, such as septic arthritis, require rapid diagnostic testing of the synovial fluid aspirated from joints level so that a surgical team can be assembled quickly. We present a diffuse reflectance spectroscopy (DRS) system for noncontact determination of infection. Using a light-tight syringe holder and fiber optic probe, diffusely reflected light from 475 to 655 nm was acquired from 18 patient samples through the wall of a syringe in a noncontact and sterile manner. We determined the reflectance ratios at two different wavelengths—<i>R</i>\u0000 <sub>490</sub>/<i>R</i>\u0000 <sub>600</sub> and <i>R</i>\u0000 <sub>580</sub>/<i>R</i>\u0000 <sub>600</sub> and found statistically significant differences (<i>p</i> < 0.05) in both ratios between the infected and noninfected groups. Critically, the <i>R</i>\u0000 <sub>490</sub>/<i>R</i>\u0000 <sub>600</sub> and <i>R</i>\u0000 <sub>580</sub>/<i>R</i>\u0000 <sub>600</sub> ratios were significantly correlated with clinical biomarkers—the white blood cell (WBC) and red blood cell (RBC) counts, respectively. This study demonstrates the potential of DRS as a rapid diagnostic tool for joint infections.</p>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"17 11","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jbio.202400213","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterization of Limbus Biomechanical Properties Using Optical Coherence Elastography 利用光学相干弹性成像技术表征韧带生物力学特性

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-09-03 DOI: 10.1002/jbio.202400275

Yubao Zhang, Yue Wang, Xiao Han, Jiahui Luo, Chuanqi Lin, Qin Zhang, Xingdao He

引用次数: 0

The Effect of Repeated Capillary Refill Tests on the Cutaneous Microcirculation 重复毛细血管再充盈试验对皮肤微循环的影响

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-09-03 DOI: 10.1002/jbio.202400098

Frida Meyer, Joakim Henricson, Chris D. Anderson, Daniel B. Wilhelms

{"title":"The Effect of Repeated Capillary Refill Tests on the Cutaneous Microcirculation","authors":"Frida Meyer, Joakim Henricson, Chris D. Anderson, Daniel B. Wilhelms","doi":"10.1002/jbio.202400098","DOIUrl":"10.1002/jbio.202400098","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The capillary refill test (CR test) is often used in emergency care, and the capillary refill time (CR time) is used to assess a patient's circulatory condition. The objective of this study was to investigate if repeated CR tests affect CR time.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Thirteen healthy volunteers had repeated CR tests performed on the sternum, forehead, and fingers. The tests were filmed using polarized reflectance spectroscopy and dedicated software for objective quantification of the CR time.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>There were no statistical differences between the first CR test in a series and the following. However, there were statistically significant differences in CR time between the different anatomical sites.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Repeated CR tests, separated by a minimum of 2 min, do not affect CR time in healthy volunteers. The site where the test is performed is of importance for CR time.</p>\u0000 </section>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"17 10","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jbio.202400098","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of REFIX Technology on the Remineralization of Artificial Early Enamel Caries Lesion by Laser Speckle Tracking Analysis 通过激光斑点跟踪分析评估 REFIX 技术对人工早期釉质龋损的再矿化作用。

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-09-02 DOI: 10.1002/jbio.202400144

Amanda Rafaelly Honório Mandetta, Maria Aparecida de Andrade Moreira Machado, Patrícia Bella Costa, Elaine Marcílio Santos, Marcela Letícia Leal Gonçalves, Ana Paula Taboada Sobral, João Vagner Pereira da Silva, Renato Araujo Prates, Alessandro Melo Deana, Sandra Kalil Bussadori

{"title":"Evaluation of REFIX Technology on the Remineralization of Artificial Early Enamel Caries Lesion by Laser Speckle Tracking Analysis","authors":"Amanda Rafaelly Honório Mandetta, Maria Aparecida de Andrade Moreira Machado, Patrícia Bella Costa, Elaine Marcílio Santos, Marcela Letícia Leal Gonçalves, Ana Paula Taboada Sobral, João Vagner Pereira da Silva, Renato Araujo Prates, Alessandro Melo Deana, Sandra Kalil Bussadori","doi":"10.1002/jbio.202400144","DOIUrl":"10.1002/jbio.202400144","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To assess the effectiveness of the REFIX technology in the remineralization process of initial caries simulated on bovine enamel. The assessment involved the analysis of backscatter intensity, which was determined from laser speckle images.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Twenty-one bovine teeth were divided into three groups: G1 and G7 were submitted to treatment with the REFIX technology for 1 and 7 days, respectively. The control group was treated with deionized water.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A significant difference in backscatter was found between the carious and sound areas in all groups (<i>p</i> = 0.0038, <i>p</i> < 0.0001, and <i>p</i> = 0.0002 for the control group, G1, and G7, respectively). The intergroup comparison revealed no significant difference among the groups studied.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>REFIX technology did not alter the optical properties of the samples of bovine teeth with simulated initial caries lesions after 1 and 7 days of treatment.</p>\u0000 </section>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"17 10","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142116496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potential of Raman-Reflectance Combination in Quantifying Liver Steatosis and Fat Droplet Size: Evidence From Monte Carlo Simulations and Phantom Studies 拉曼-反射组合在量化肝脏脂肪变性和脂肪滴大小方面的潜力：来自蒙特卡罗模拟和模型研究的证据。

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-09-02 DOI: 10.1002/jbio.202400156

Hao Guo, Vanessa S. Zions, Brent A. Law, Kevin C. Hewitt

引用次数: 0

Shot-Noise Limited Nonlinear Optical Imaging Excited With GHz Femtosecond Pulses and Denoised by Deep-Learning 用 GHz 飞秒脉冲激发并通过深度学习去噪的镜头噪声受限非线性光学成像。

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-09-01 DOI: 10.1002/jbio.202400186

Wenlong Wang, Junpeng Wen, Yuke Sheng, Chiyi Wei, Cihang Kong, Yalong Liu, Xiaoming Wei, Zhongmin Yang

{"title":"Shot-Noise Limited Nonlinear Optical Imaging Excited With GHz Femtosecond Pulses and Denoised by Deep-Learning","authors":"Wenlong Wang, Junpeng Wen, Yuke Sheng, Chiyi Wei, Cihang Kong, Yalong Liu, Xiaoming Wei, Zhongmin Yang","doi":"10.1002/jbio.202400186","DOIUrl":"10.1002/jbio.202400186","url":null,"abstract":"<div>\u0000 \u0000 <p>Multiphoton fluorescence microscopy excited with femtosecond pulses at high repetition rates, particularly in the range of 100's MHz to GHz, offers an alternative solution to suppress photoinduced damage to biological samples, for example, photobleaching. Here, we demonstrate the use of a U-Net-based deep-learning algorithm for suppressing the inherent shot noise of the two-photon fluorescence images excited with GHz femtosecond pulses. With the trained denoising neural network, the image quality of the representative two-photon fluorescence images of the biological samples is shown to be significantly improved. Moreover, for input raw images with even SNR reduced to −4.76 dB, the trained denoising network can recover the main image structure from noise floor with acceptable fidelity and spatial resolution. It is anticipated that the combination of GHz femtosecond pulses and deep-learning denoising algorithm can be a promising solution for eliminating the trade-off between photoinduced damage and image quality in nonlinear optical imaging platforms.</p>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"17 10","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142116500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Noninvasive Assessing Low Back Pain by a Novel Near-Infrared Spectroscopy Flexible Probe With the Aid of Cupping Protocol 利用新型近红外光谱柔性探针和拔罐疗法进行无创腰痛评估

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-09-01 DOI: 10.1002/jbio.202400204

Bowen Zhang, Yu Lin, Bo Yao, Ting Li

{"title":"Noninvasive Assessing Low Back Pain by a Novel Near-Infrared Spectroscopy Flexible Probe With the Aid of Cupping Protocol","authors":"Bowen Zhang, Yu Lin, Bo Yao, Ting Li","doi":"10.1002/jbio.202400204","DOIUrl":"10.1002/jbio.202400204","url":null,"abstract":"<div>\u0000 \u0000 <p>Low back pain (LBP) is the leading cause of disability worldwide, yet its quantitative and noninvasive assessment remains challenging. Considering that near-infrared spectroscopy (NIRS) became a promising noninvasive tool for monitoring muscle and cupping therapy could regulate muscle blood flow to relieve LBP, we attempted to incorporate cupping and hemodynamics monitoring in muscle tissue by NIRS to assess LBP. We collected 3-min NIRS recordings on 12 LBP patients and 12 healthy subjects before and after 20-min cupping. Initially, no significant hemodynamic differences were observed between the groups. After cupping, the concentration changes of oxy-hemoglobin (Δ[HbO<sub>2</sub>]) in the emitter-detector channel parallel to spine unexpectedly exhibited that LBP was remarkably lower by approximately 67% compared with the controls. This study highlighted the potential of combining NIRS and cupping protocol as a quantitative assessment technique for LBP, also providing a new idea for clinical integration of novel optical assessment technologies.</p>\u0000 </div>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"17 10","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142116498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post-Surgical Non-Invasive Wound Healing Monitoring in Oropharyngeal Mucosa 口咽黏膜术后非侵入性伤口愈合监测

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-08-29 DOI: 10.1002/jbio.202400248

Anastasia Guryleva, Alexander Machikhin, Alexey Toldanov, Yevgeniya Kulikova, Demid Khokhlov, Anastasia Zolotukhina, Mikhail Svistushkin, Valeriy Svistushkin

引用次数: 0

Effects of Photobiomodulation Application on Glutathione-Related Antioxidant Defense System in Rabbit Eye Tissues 光生物调节应用对兔眼部组织谷胱甘肽相关抗氧化防御系统的影响

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-08-29 DOI: 10.1002/jbio.202400261

Mehmet Ozcan, Ayse Burus, Etkin Boynuyogun, Mert Calis, Figen Ozgur, Yasemin Bayazit

{"title":"Effects of Photobiomodulation Application on Glutathione-Related Antioxidant Defense System in Rabbit Eye Tissues","authors":"Mehmet Ozcan, Ayse Burus, Etkin Boynuyogun, Mert Calis, Figen Ozgur, Yasemin Bayazit","doi":"10.1002/jbio.202400261","DOIUrl":"10.1002/jbio.202400261","url":null,"abstract":"<p>Photobiomodulation (PBM) has emerged as a potentially effective therapeutic approach to modulate cellular functions. This study aimed to examine the impact of PBM on reactive oxygen species (ROS), lipid peroxidation, and glutathione-related antioxidant defense systems in rabbit eye tissues. A polychromatic light source with an intensity of 2.6 J/cm<sup>2</sup>/min was used for PBM treatment in New Zealand White rabbits for 12 min. The PBM group (<i>n</i> = 8) received treatments every 2 days for a total of 12 sessions, whereas the control group (<i>n</i> = 8) did not undergo any PBM light exposure during the same period. The application of PBM significantly elevated ROS-mediated glutathione levels, along with increased activities of glutathione peroxidase and reductase, particularly in corneal tissue (<i>p</i> ≤ 0.05). In conclusion, PBM treatment effectively enhances antioxidant defense mechanisms in the eye, particularly in corneal tissue, suggesting its potential as a therapeutic strategy for managing oxidative stress-related ocular conditions.</p>","PeriodicalId":184,"journal":{"name":"Journal of Biophotonics","volume":"17 10","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jbio.202400261","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142116518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Induction of Endoplasmic Reticulum Stress and Aryl Hydrocarbon Receptor Pathway Expression by Blue LED Irradiation in Oral Squamous Cell Carcinoma 蓝光 LED 照射诱导口腔鳞状细胞癌的内质网应激和芳香烃受体通路表达

IF 2 3区物理与天体物理

Journal of Biophotonics Pub Date : 2024-08-29 DOI: 10.1002/jbio.202400226

Hui Jiang, Jiali Yang, Qiqi Fu, Angze Li, Haokuan Qin, Muqing Liu

引用次数: 0