Advanced Intervention Effects of Pulsed and Steady Transcranial Photobiomodulation on Sleep, Mood, and EEG Signal Regulation

IF 2 3区物理与天体物理 Q3 BIOCHEMICAL RESEARCH METHODS

Journal of Biophotonics Pub Date : 2025-03-18 DOI:10.1002/jbio.70004

Xuran Zhang, Xiaojing Miao, Hui Jiang, Yi Ren, Longfei Huo, Muqing Liu, Houbo Chen

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引用次数: 0

Abstract

Background

Transcranial photobiomodulation (tPBM) enhances cognitive and emotional states. We compared continuous-wave (CW) and pulsed-wave (PW) tPBM effects on 24 healthy males.

Method

Participants received 630 nm tPBM at 95 mW/cm² for 10 min: Sham, CW, or PW (500 Hz). Outcomes were assessed using the Karolinska Sleepiness Scale (KSS) (for measuring sleepiness), State-Trait Anxiety Inventory (STAI) (for assessing anxiety), Visual Analog Scale (VAS) (for measuring stress), and Beck Depression Inventory-II (BDI-II) (for evaluating depressive symptoms), and 32-channel EEG at baseline, treatment, and rest phases.

Results

Paired t-tests showed PW tPBM significantly improved sleepiness, anxiety, stress, and depression scores post-intervention (p < 0.05). ANOVA analyses indicated PW tPBM increased Alpha and Gamma band EEG power versus baseline (p < 0.05).

Conclusion

PW tPBM may improve cognitive and emotional outcomes and modulate brain activity, offering therapeutic insights.

查看原文本刊更多论文

脉冲和稳定经颅光生物调节对睡眠、情绪和脑电图信号调节的高级干预作用。

背景：经颅光生物调节（tPBM）增强认知和情绪状态。我们比较了连续波（CW）和脉冲波（PW）对24名健康男性的tPBM效果。方法：参与者以95 mW/cm2的速度接受630 nm tPBM，持续10分钟：Sham， CW或PW （500 Hz）。使用卡罗林斯卡嗜睡量表（KSS）（用于测量嗜睡）、状态-特质焦虑量表（STAI）（用于评估焦虑）、视觉模拟量表（VAS）（用于测量压力）和贝克抑郁量表- ii (BDI-II)（用于评估抑郁症状）以及基线、治疗和休息阶段的32通道脑电图来评估结果。结果：配对t检验显示，PW tPBM可显著改善干预后的嗜睡、焦虑、压力和抑郁评分(p)。结论：PW tPBM可改善认知和情绪结果，调节大脑活动，提供治疗见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Biophotonics 生物-生化研究方法

CiteScore

5.70

自引率

7.10%

发文量

248

审稿时长

1 months

期刊介绍： The first international journal dedicated to publishing reviews and original articles from this exciting field, the Journal of Biophotonics covers the broad range of research on interactions between light and biological material. The journal offers a platform where the physicist communicates with the biologist and where the clinical practitioner learns about the latest tools for the diagnosis of diseases. As such, the journal is highly interdisciplinary, publishing cutting edge research in the fields of life sciences, medicine, physics, chemistry, and engineering. The coverage extends from fundamental research to specific developments, while also including the latest applications.