Marco Antonio Rivera Rodriguez, Verónica Campos-Ibarra, Aruna-Devi Rasu Chettiar, Latha Marasamy, Ravichandran Manisekaran
{"title":"Anticancer effect of surface functionalized nano titanium dioxide with 5-fluorouracil on oral cancer cell line—An in vitro study","authors":"Marco Antonio Rivera Rodriguez, Verónica Campos-Ibarra, Aruna-Devi Rasu Chettiar, Latha Marasamy, Ravichandran Manisekaran","doi":"10.1049/mna2.70004","DOIUrl":"https://doi.org/10.1049/mna2.70004","url":null,"abstract":"<p>5-Fluorouracil (5-FU) is a chemotherapeutic agent widely used to treat different types of cancers. However, many patients present with obstacles during treatment due to 5-FU drug resistance. To overcome these drawbacks, a novel drug-loaded nanocarrier (NC) comprising titanium dioxide (TiO<sub>2</sub>) nanoparticles surface functionalized with 5-FU to facilitate drug delivery is developed. This study designs and evaluates the antitumour effects of NCs in oral cancer (OC) cell lines of lymphoid origin. NCs were synthesized by biofunctionalization of TiO<sub>2</sub> nanoparticles with 3-aminopropyl triethoxysilane (APTES) which was then loaded with 5-FU. in vitro drug release was determined at three different pH values. The effect of chemotherapy was studied in mono- and co-culture systems comprising OC cells and human gingival fibroblasts (hGFs). From these studies, it is noted that after 24 h in an acidic medium (pH 5.5), more than 80% of 5-FU was released compared to that at basic pH. The cytotoxicity was higher when 5-FU was combined with the system TiO<sub>2</sub>-APTES, in comparison with 5-FU alone was used. The drug-loaded NC showed an increased antitumour effect in the OC cell line with minimal cytotoxicity to hGFs. The anticancer effect of TiO<sub>2</sub>/5-FU could be highly effective in the tumour microenvironment.</p>","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.70004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142447725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zahra Foroutan, Zahra Sabouri, Amir Reza Afshari, Asma Mostafapour, Bahareh Farasati Far, Mohammad Jalili-Nik, Majid Darroudi
{"title":"Green synthesis of cerium oxide nanoparticles via Linum usitatissimum seeds extract and assessment of its biological effects","authors":"Zahra Foroutan, Zahra Sabouri, Amir Reza Afshari, Asma Mostafapour, Bahareh Farasati Far, Mohammad Jalili-Nik, Majid Darroudi","doi":"10.1049/mna2.70003","DOIUrl":"https://doi.org/10.1049/mna2.70003","url":null,"abstract":"<p>In the current work, CeO<sub>2</sub>-NPs were produced via a green chemistry process via <i>Linum usitatissimum</i> seeds extract as the stabilizing agent. The CeO<sub>2</sub>-NPs were characterized by the results of analytical techniques such as TGA/DTA, FTIR, UV–vis, XPS, XRD, and FESEM/PSA/EDX. The outcomes of the XRD pattern affirmed the crystalline structure of this product with the suggested size of about 20 nm, while the FESEM/PSA pictures presented spherical morphology. Additionally, the XPS analysis of CeO<sub>2</sub>-NPs affirmed the presence of a Ce<sup>+3</sup> oxidation state in the sample, as well as Ce<sup>+4</sup> as the major valence of cerium oxide. The results of the MTT test on Huh-7 cancer cells and HFF normal cells displayed the lack of any significant cytotoxicity even at concentrations up to 1000 µg/mL. Therefore, the obtained synthesized CeO<sub>2</sub>-NPs through this green method could be suggested as a prospective agent for medical applications due to its non-toxic effects.</p>","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.70003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142435357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Faraz Hashmi, M Nizamuddin, Mohammad Aleem Farshori, Syed Umar Amin, Zafar Iqbal Khan
{"title":"Graphene nanoribbon FET technology-based OTA for optimizing fast and energy-efficient electronics for IoT application: Next-generation circuit design","authors":"Faraz Hashmi, M Nizamuddin, Mohammad Aleem Farshori, Syed Umar Amin, Zafar Iqbal Khan","doi":"10.1049/mna2.70002","DOIUrl":"https://doi.org/10.1049/mna2.70002","url":null,"abstract":"<p>The Internet of Things (IoT) and portable electronic devices are pivotal in enhancing living standards, with battery efficiency and compact design being critical for these devices. Analogue sensors, integral to advanced artificial intelligence, often necessitate complex real-time processing and actuation. This study examines the performance of one-dimensional armchair graphene nanoribbons in graphene nanoribbon field-effect transistors (GNRFETs). It compares graphene nanoribbon-based triple cascode operational transconductance amplifiers (GNRFET-TCOTAs) with conventional CMOS-based TCOTA. The results reveal substantial enhancements in the GNRFET-based TCOTAs: the pure GNR-TCOTA variant shows a remarkable 33.8% increase in DC gain and significant improvements in transconductance, slew rate, and gain-bandwidth, with enhancements of 8.48, 5.85, and 8.56 times, respectively. Furthermore, the pure GNRFET TCOTA exhibits higher speed, lower energy-delay product, and settling time compared to Si-CMOS-based TCOTA. The study also investigates the impact of critical design parameters on circuit performance. Overall, the research highlights the potential of GNRFETs to optimize TCOTA circuits, offering a path towards more efficient and compact electronic devices, thereby advancing the state of nanoelectronics and supporting the growth of high-performance IoT systems.</p>","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.70002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142404755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Construction of ZnCo2O4/Ag3PO4 composite photocatalyst for enhanced photocatalytic performance","authors":"Jiayi Liu, Jiafeng Hu, Hao Hu, Xiaotao Zhou, Qiwei Wang, Weizhi Wei, Wenhui Liu","doi":"10.1049/mna2.12202","DOIUrl":"https://doi.org/10.1049/mna2.12202","url":null,"abstract":"<p>In this study, ZnCo<sub>2</sub>O<sub>4</sub>/Ag<sub>3</sub>PO<sub>4</sub> composite catalyst was prepared by the precipitation method, and their performance in the photocatalytic degradation of methyl orange (MO) was studied. The catalysts were characterized by scanning electron microscopy, high-resolution transmission electron microscopy, X-ray diffraction, energy-dispersive X-ray spectroscopy, selected area electron diffraction, X-ray photoelectron spectroscopy, and UV-Vis diffuse reflectance spectroscopy. The results indicate that the 0.1 ZnCo<sub>2</sub>O<sub>4</sub>/Ag<sub>3</sub>PO<sub>4</sub> composite system has good photocatalytic activity in the degradation of methyl orange. Under simulated sunlight conditions, the degradation rate can reach 94% after 30 min. The maximum reaction rate constant of 0.1 ZnCo<sub>2</sub>O<sub>4</sub>/Ag<sub>3</sub>PO<sub>4</sub> was 0.05301 min<sup>−1</sup>, which is 3 times and 52 times the rate constant of pure Ag<sub>3</sub>PO<sub>4</sub> and pure ZnCo<sub>2</sub>O<sub>4</sub>, respectively. In catalyst recycling experiments, 0.1 ZnCo<sub>2</sub>O<sub>4</sub>/Ag<sub>3</sub>PO<sub>4</sub> still degraded methyl orange at a rate of 84.4% after three cycles. Trapping experiments showed that holes and superoxide radicals mostly contributed to the photocatalytic degradation of methyl orange by the catalyst, while hydroxyl radicals played a partial role. The energy level structure of ZnCo<sub>2</sub>O<sub>4</sub>/Ag<sub>3</sub>PO<sub>4</sub> is conducive to the effective separation of photogenerated electrons and holes, improving the lifespan of photogenerated charges. In the investigated catalyst series, 0.1 ZnCo<sub>2</sub>O<sub>4</sub>/Ag<sub>3</sub>PO<sub>4</sub> demonstrated the best photocatalytic performance.</p>","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.12202","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142316668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Microcapsule preparation process research and current status of oilfield application","authors":"Sicai Wang, Qun Zhang, Jianlong Xiu, Yuandong Ma, Lixin Huang, Lina Yi, Haowei Fu","doi":"10.1049/mna2.70000","DOIUrl":"https://doi.org/10.1049/mna2.70000","url":null,"abstract":"<p>Traditional tertiary oil recovery methods are fraught with challenges such as significant reagent adsorption, voluminous injection requirements, limited sweep efficiency, and inadequate intelligent targeting. These issues lead to suboptimal displacement of residual oil, resulting in the inability to mobilize substantial crude oil resources and thus yielding low recovery rates. Microcapsules—spherical particles with micron or nanometer scale diameters—have been extensively utilized across various sectors, including food storage, targeted drug encapsulation, and fragrance containment, owing to their distinct advantages in controlled release, isolation, and targeted delivery. These applications have successfully achieved industrialization and commercialization. In recent years, numerous researchers have explored the application of microcapsule preparation processes to diverse facets of oil extraction, with the aim of further enhancing oil recovery (EOR). This article elucidates the mechanism of action of microcapsules, their preparation methods (encompassing in situ polymerization, interfacial polymerization, spray drying, solvent evaporation, phase separation, and supercritical CO<sub>2</sub>-assisted techniques), characterization and evaluation methodologies, among other aspects. It encapsulates the current status and principal challenges associated with the application of microcapsule preparation processes in oilfield development and probes the potential and pivotal research directions for their oilfield applications.</p>","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.70000","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142100461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Na Li, Guirong Feng, Lingling Jiao, Ping Li, Xiaowei Shi
{"title":"Generation of dual-mode PS-OAM beams using a Vivaldi antenna array","authors":"Na Li, Guirong Feng, Lingling Jiao, Ping Li, Xiaowei Shi","doi":"10.1049/mna2.70001","DOIUrl":"https://doi.org/10.1049/mna2.70001","url":null,"abstract":"<p>The paper proposes a single antenna that can generate dual-mode plane spiral orbital angular momentum (PS-OAM) beams. Six Vivaldi antennas placed in a tangential circular array make up the antenna, and the antenna is etched onto a substrate material and has a flat design, allowing for easy integration with other system components. The neighbouring ports of the antenna elements have phase differences, so phase-shifting in the feeding network is unnecessary. When fed with the same phase and amplitude, the antenna can produce PS-OAM beams with mode +1 at 7 GHz and mode +2 at 14 GHz, and the measured purity is 80.6% and 63%, respectively. The method may provide a new way to produce multi-mode orbital angular momentum.</p>","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.70001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142077762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nonmonotonic load-dependence of friction during nanoparticle manipulation","authors":"Chunsheng Luo, Lei Chen, Chuan Tang, Yangqin Liu, Yilong Jiang, Linmao Qian","doi":"10.1049/mna2.12206","DOIUrl":"https://doi.org/10.1049/mna2.12206","url":null,"abstract":"<p>The tribological behaviors of nanoparticles (NPs) have attracted widespread attention in the fields of nano-lubrication and ultra-precision manufacturing. The frictional and dynamic behaviors of SiO<sub>2</sub> NPs acting with the single asperity were studied on silicon surface utilizing atomic force microscope. The friction forces of NPs, both static and kinetic, exhibit an initial decrease followed by an increase as the normal load increases (0–300 nN). The nonmonotonic load-dependence of friction behavior corresponds to the dynamic transformation of “sliding-rolling-sliding” motion state of the manipulated NPs, which can be predicted by a Double-Hertz model and further confirmed by nanoindentation-marked NPs. This research has a significant implication for regulating dynamic behaviors of NPs in contemporary three-body abrasive tribology.</p>","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.12206","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141730232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biomass N/P co-doped porous carbon plates for electrocatalytic oxygen reduction","authors":"Hongwei Ma, Daying Guo, Lianhui Wu, Xi'an Chen","doi":"10.1049/mna2.12199","DOIUrl":"https://doi.org/10.1049/mna2.12199","url":null,"abstract":"<p>Nitrogen and phosphorus co-doped porous carbon plate (NPCP) was prepared by simple pyrolysis carbonization and alkali activation of biomass duckweed NPCP displays the largest specific surface area (SSA) of 2023 m<sup>2</sup> g<sup>−1</sup>, and is rich in pyridine N and P doping, which makes the metal-free carbon have excellent electrocatalytic oxygen reduction performance. The best NPCP2 shows a half-wave potential of 0.19 V vs. Ag/AgCl in alkaline electrolyte, and its activity is equivalent to that of commercial platinum carbon (Pt/C). In addition, it shows excellent methanol toxicity resistance and continuous catalytic stability. The experimental results show that the heteroatom doping method obtained by biomass hydroponics has great advantages and great application value in the catalytic field of porous carbon materials.</p>","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.12199","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141565828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mukilan Karuppasamy, Baranitharan Balakrishnan, Karthik Chandran, Mehdi Gheisari, Payam Porkar Rezaeiye, Boris Andrievsky
{"title":"Analysis of mechanical properties in self-compacting concrete enhanced with steel fibres","authors":"Mukilan Karuppasamy, Baranitharan Balakrishnan, Karthik Chandran, Mehdi Gheisari, Payam Porkar Rezaeiye, Boris Andrievsky","doi":"10.1049/mna2.12203","DOIUrl":"https://doi.org/10.1049/mna2.12203","url":null,"abstract":"<p>This study explores the effect of incorporating steel fibres and fly ash into self-compacting concrete (SCC) in various combinations on its mechanical properties. The study begins with thoroughly investigating the fresh properties to ensure compliance with SCC standards when adding steel fibres. Subsequently, mixes that meet SCC standards are evaluated for their mechanical properties. The study aims to enhance the mechanical properties of SCC while maintaining its flowability, filling ability, and passing ability. The research findings provide valuable insights into the optimal combination of steel fibres and fly ash for improving the mechanical properties of SCC. The addition of hooked end type steel fibres increases the compressive strength. When compared to crimped type the mechanical properties increased to 14.4%; however, the strength decreases beyond 1% of steel fibres. Satisfactory results are obtained for fresh properties test.</p>","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.12203","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141488677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rongguang Zhang, Xun Chen, Han Wang, Jun Zeng, Xuanzhi Zhang, Xiaojie Chen
{"title":"Study on uniformity of multi-needle electrostatic spinning by auxiliary flow field","authors":"Rongguang Zhang, Xun Chen, Han Wang, Jun Zeng, Xuanzhi Zhang, Xiaojie Chen","doi":"10.1049/mna2.12200","DOIUrl":"https://doi.org/10.1049/mna2.12200","url":null,"abstract":"<p>Multi-needle electrospinning is a simple and general method for mass preparation of nanofiber membrane, which has great industrial potential. However, the bending instability produced in the electrospinning process makes that the deposition uniformity of the nanofiber is still a big concern, resulting in non-uniform nanofiber membrane, which seriously affects the application of electrospun membrane in environmental filtration, new energy and medical fields. In order to improve the uniformity of nanofiber deposition in multi-needle electrospinning, an auxiliary flow field system (AFF) is proposed, which can effectively improve the uniformity of nanofiber deposition. After image processing, the uniformity of nanofiber deposition is quantified with the index of grey distribution, and the effectiveness of this method is verified. Combined with the multi-physical field analysis, the influence mechanism of cross-wind field on the uniformity of fibre deposition was revealed. By optimizing the experimental parameters, the non-uniformity of nanofiber deposition was reduced by 49.19%. Based on multi-needle electrospinning technology, a reliable idea (AFF) and experimental basis are provided for the uniform preparation of nanofiber membrane.</p>","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.12200","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141069078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}