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Management of nerve injury by curcumin after sevoflurane anesthesia in gastric cancer through MAPK signaling pathway 姜黄素通过 MAPK 信号通路控制七氟醚麻醉后胃癌患者的神经损伤
IF 0.7 4区 材料科学
Materials Express Pub Date : 2023-12-01 DOI: 10.1166/mex.2023.2545
Jianguang Ren, Ben Cai
{"title":"Management of nerve injury by curcumin after sevoflurane anesthesia in gastric cancer through MAPK signaling pathway","authors":"Jianguang Ren, Ben Cai","doi":"10.1166/mex.2023.2545","DOIUrl":"https://doi.org/10.1166/mex.2023.2545","url":null,"abstract":"Currently, surgery is the only treatment that can completely remove gastric tumor. This study investigated the effect of curcumin on sevoflurane anesthesia-induced nerve damage in rats with gastric cancer (GC). A rat GC model was established and received sevoflurane for anesthesia.\u0000 The rats were then divided into model group, low-dose (20 mg/kg), high-dose (60 mg/kg) group and blank control group (n = 5, each group). To identify the interaction between curcumin and mitogen-activated protein kinase (MAPK) expression, we set up MAPK mimic group, MAPK inhibitor group,\u0000 and high-dose curcumin+MAPK inhibitor group (n = 5). The cognitive ability of rats after anesthesia and neuronal damage was assessed using Morris water maze test, whilst the expressions of brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF) and pyroptosis were also detected.\u0000 Administration of curcumin attenuated neuronal injury and pyroptosis in the hippocampus induced by sevoflurane, and facilitated the recovery of memory impairment in rats, resulting in decreased expression of MAPK and increased expressions of BNDF and NGF. After treatment with MAPK inhibitors,\u0000 the nerve damage in the rat hippocampus tissue was controlled, and more prominently neuroprotective effect appeared in the curcumin high-dose+MAPK inhibitor group. Curcumin can thus effectively up-regulate BNDF and NGF in hippocampal tissue, which is closely related to inhibited MAPK pathway\u0000 activity. Curcumin protects the nervous system by inhibiting the expression of pyroptin, contributing toimprovement of cognitive impairment in rats.","PeriodicalId":18318,"journal":{"name":"Materials Express","volume":" 40","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138611707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preparation of functionalized polymer nanomaterials and application in renal injury 功能化聚合物纳米材料的制备及其在肾损伤中的应用
IF 0.7 4区 材料科学
Materials Express Pub Date : 2023-12-01 DOI: 10.1166/mex.2023.2554
Qin Liu
{"title":"Preparation of functionalized polymer nanomaterials and application in renal injury","authors":"Qin Liu","doi":"10.1166/mex.2023.2554","DOIUrl":"https://doi.org/10.1166/mex.2023.2554","url":null,"abstract":"Renal injury, which is a prevalent condition, significantly impacts the health of competitive wrestlers. However, there is a limited number of therapeutic methods and drugs available for its treatment. To tackle this issue, a renal targeted drug based on functionalized polymer nanoparticles\u0000 (FPNPs) is being studied. The primary methods in the preparation of FPNPs involve utilizing the thin film hydration technique to create nanoparticles and encapsulating the drug TP within them as a treatment for renal injury, thus forming TP-FPNPs. Subsequently, the renal targeting of TP-FPNPs\u0000 is analyzed using in vitro organ fluorescence imaging techniques. Furthermore, a renal IRI model is constructed to assess the pharmacokinetics of TP-FPNPs using the application method. The preparation results of TP-FPNPs reveal a hydrated particle size of approximately 90 nm, which\u0000 remains in the renal region for over 48 hours. Additionally, the concentration content surpasses that of other organs by more than threefold after 12 hours. Moreover, in the application results, TP-FPNPs continue to possess a concentration of 302.5 ng/g even after 48 hours post-injection.\u0000 Based on the aforementioned results, it can be concluded that TP-FPNPs exhibit specific targeting, biocompatibility, and an extended retention time. Thus, this study is expected to effectively achieve the effect of treating renal injury in martial arts athletes, establishing an experimental\u0000 foundation for its clinical treatment.","PeriodicalId":18318,"journal":{"name":"Materials Express","volume":" 2","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138613458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Total glucosides of peony regulate toll-like receptor to inhibit inflammatory response in diabetic nephropathy 牡丹总苷调节收费样受体,抑制糖尿病肾病的炎症反应
IF 0.7 4区 材料科学
Materials Express Pub Date : 2023-12-01 DOI: 10.1166/mex.2023.2568
Lang Li, Huan Wang, Chunyu Zhao
{"title":"Total glucosides of peony regulate toll-like receptor to inhibit inflammatory response in diabetic nephropathy","authors":"Lang Li, Huan Wang, Chunyu Zhao","doi":"10.1166/mex.2023.2568","DOIUrl":"https://doi.org/10.1166/mex.2023.2568","url":null,"abstract":"Diabetic nephropathy (DN) is a common chronic disease affecting people’s life. Total glucosides of peony (TGP) regulates TLR4/NF-κB activation. This study aims at investigating the underlying mechanism of TGP in DN treatment. A retrospective analysis of clinical data\u0000 was conducted to observe periodic acid-silver metheramine (PASM) staining and detect the expression of TLR4 and VEGF in DN. Additionally, rats were injected with Streptozocin (STZ) (30–60 mg) according to the ratio of 45–65 mg/kg to establish DN model. 8 weeks later, rats of experimental\u0000 group were intraperitoneally injected with TGP. Kidney was collected for HE staining to observe morphological changes. Fibronectin expression was detected by histochemistry and the level of TLR4/NF-κB pathway-related proteins and apoptosis were detected by Western blot. PASM staining\u0000 revealed focal tubular atrophy and interstitial fibrosis in DN patients. The renal medulla gradually disappeared and infiltration increased in control group, while inflammatory cells decreased in experimental group. The expression of fibronectin, TLR4 and p-p65 was decreased after TGP treatment.\u0000 TGP treatment significantly decreased fibronectin expression and TGP treatment-induced inhibition of NF-κB signaling enhanced apoptotic activation of HK-2 cells, which was partially reversed by TLR4 and NF-κB inhibitors. TGP can inhibit inflammatory response of DN\u0000 via regulating TLR4/NF-κB.","PeriodicalId":18318,"journal":{"name":"Materials Express","volume":" 24","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138611459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of combining nano-silver dressing and vacuum sealing drainage with negative pressure treatment on patients with diabetic foot ulcers 纳米银敷料和真空密封引流与负压治疗相结合对糖尿病足溃疡患者的影响
IF 0.7 4区 材料科学
Materials Express Pub Date : 2023-12-01 DOI: 10.1166/mex.2023.2566
Liang Jin, Chao Niu, Yulong Ni
{"title":"Effect of combining nano-silver dressing and vacuum sealing drainage with negative pressure treatment on patients with diabetic foot ulcers","authors":"Liang Jin, Chao Niu, Yulong Ni","doi":"10.1166/mex.2023.2566","DOIUrl":"https://doi.org/10.1166/mex.2023.2566","url":null,"abstract":"This study investigates the efficiency of the combination of nano-silver dressing and vacuum sealing drainage (VSD) with negative pressure treatment on healing diabetic foot ulcers (DFU). A total of 100 patients with DFU admitted to our hospital between January 2022 and February 2023\u0000 were selected and randomly divided into a control group and an observation group, each consisting of 50 cases. Both groups received nano-silver dressings after debridement, but the observation group also underwent closed negative pressure drainage. Scores for wound granulation morphology and\u0000 comfort were assessed before and after treatment. Efficacy rate, healing time, and clinical outcomes were evaluated before and after treatment. Serum levels of procalcitonin (PCT), high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), and cystatin C were measured before treatment\u0000 and 30 days into treatment. After 10 days of treatment, the observation group showed a higher effective rate (96%) compared to the control group (88%). The observation group had better wound granulation morphology and comfort scores, shorter granulation and healing times, reduced hospitalization\u0000 duration, and smaller wound areas than the control group. Both groups experienced decreased levels of IL-6, PCT, hs-CRP, and cystatin C after treatment. The observation group had lower levels of these markers compared to the control group. In conclusion, the combination of nano-silver dressing\u0000 and VSD with negative pressure treatment improves the clinical efficacy of treating DFU. This approach reduces inflammation and promotes wound healing, as evidenced by improved wound scores, faster healing times, and reduced inflammatory marker levels.","PeriodicalId":18318,"journal":{"name":"Materials Express","volume":" 10","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138617054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis of fluorescent 9-(4-aminoaniline)-acridine for highly specific and rapid detection of human serum albumin by fluorescence-capillary gel electrophoresis 合成荧光 9-(4-氨基苯胺)-吖啶,用于通过荧光-毛细管凝胶电泳高度特异性地快速检测人血清白蛋白
IF 0.7 4区 材料科学
Materials Express Pub Date : 2023-12-01 DOI: 10.1166/mex.2023.2571
Jing Ye, Tianxiang Hu, Hui Ding, Xiawei Dong
{"title":"Synthesis of fluorescent 9-(4-aminoaniline)-acridine for highly specific and rapid detection of human serum albumin by fluorescence-capillary gel electrophoresis","authors":"Jing Ye, Tianxiang Hu, Hui Ding, Xiawei Dong","doi":"10.1166/mex.2023.2571","DOIUrl":"https://doi.org/10.1166/mex.2023.2571","url":null,"abstract":"In clinical practice, many diseases can lead to changes in serum albumin concentration (HSA) in patients. Accurate detection of HSA concentration is of great significance for disease diagnosis. Based on this, this study designed and synthesized 9-(4-amino-aniline)-acridine (AAA) as\u0000 a fluorescent probe. By laser induction and capillary gel electrophoresis (CGE), a new rapid and highly specific HSA detection method based on fluorescence-CGE was established. Various experimental control factors were investigated, and the optimal experimental conditions were determined as\u0000 follows: the running buffer was H3PO4–KH2PO4 (pH = 2.45, 15.0 mmol L−1), the separation voltage was 30 kV, and the experimental temperature was 25 °C. The sample solution injected 10 s with hydrodynamic mode (3.43×103\u0000 Pa), HSA could be directly determined by fluorescence-CGE method. The linear range was 0.10–1.0 μg L−1, the detection limit was 0.012 μg L−1, the relative standard deviation (RSD) was less than 0.30%. This method can be used for the\u0000 determination of real HSA samples. In addition, in the presence of various biological macromolecules, small molecules, ions and ethanol, the accurate detection of HSA by fluorescence-CGE method will not be affected, suggesting that this method has a high specificity for HSA. The rapid and\u0000 highly specific fluorescence-CGE method of HSA constructed in this study provides a new way to detect HSA, which is of great significance for the diagnosis of clinical diseases.","PeriodicalId":18318,"journal":{"name":"Materials Express","volume":" 3","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138618394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3D modeling of the airflow and aerosol deposition in the existence of dust 气流和气溶胶沉积在尘埃中的三维模型
IF 0.7 4区 材料科学
Materials Express Pub Date : 2023-12-01 DOI: 10.1166/mex.2023.2563
O. Altwijri, Razan Bakhshwin, E. H. Mirza, Y. A. Algabri, S. Chatpun, Ravish Javed
{"title":"3D modeling of the airflow and aerosol deposition in the existence of dust","authors":"O. Altwijri, Razan Bakhshwin, E. H. Mirza, Y. A. Algabri, S. Chatpun, Ravish Javed","doi":"10.1166/mex.2023.2563","DOIUrl":"https://doi.org/10.1166/mex.2023.2563","url":null,"abstract":"Annually, more than two million deaths are caused due to the exposure of air pollution which cause damage to the lungs and the respiratory system. Topography, light-textured topsoil, drought, and desert climate make Saudi Arabia vulnerable to sand storms and dust. The study aims to\u0000 examine the deposition of dust particles in the human airway and its relationship to asthma and investigate the possibility that the dust deposition would be changed with different particle size diameters. An idealized upper respiratory tract 3D model was constructed with computer-aided design\u0000 software. Later a computational simulation was performed using computational fluid dynamics with 3 different sizes (0.03, 2, and 9 microns) of the dust particles to find out the change in airflow velocity and pressure. Our findings revealed that small size particles will travel more with less\u0000 inertia, whereas bigger size particles will travel less but with higher inertia at airflow rates of 30 L/min. It was found that dust deposition in the respiratory system determines the probability of inhalation and total deposition in the alveoli greatly varies with particle diameter size.\u0000 An idealized URT model replicate patient-specific URT geometry which helped in finding real-time airflow velocity and pressure of dust particles. Particles with smaller diameter are capable of 100% deposition and inhalation rate at the alveoli, whereas particles with bigger diameter tend to\u0000 deposit less and with lower inhalation rates at the alveoli.","PeriodicalId":18318,"journal":{"name":"Materials Express","volume":"72 2","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138622864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
LSD1 inhibitor hinders the demethylation of FOXA1 to inhibit prostate cancer progression LSD1 抑制剂阻碍 FOXA1 的去甲基化,从而抑制前列腺癌的进展
IF 0.7 4区 材料科学
Materials Express Pub Date : 2023-12-01 DOI: 10.1166/mex.2023.2567
Yongzhen Zhu, Lijia Ma, Wen Zhang, Xuelian Wu
{"title":"LSD1 inhibitor hinders the demethylation of FOXA1 to inhibit prostate cancer progression","authors":"Yongzhen Zhu, Lijia Ma, Wen Zhang, Xuelian Wu","doi":"10.1166/mex.2023.2567","DOIUrl":"https://doi.org/10.1166/mex.2023.2567","url":null,"abstract":"Abnormal activation of androgen receptor (AR) occurs in prostate cancer (PC) progression and metastasis. Lysine-specific demethylase 1 (LSD1), the first demethylating enzyme, regulates AR-mediated transcriptional activity. Considering the effect of Forkhead box protein A1 (FOXA1) on\u0000 the expression of AR, estrogen receptor (ER) and tumor suppressor genes, this study investigated the demethylation of FOXA1 upon treatment with LSD1 inhibitors and assessed the biological behaviors of PC cells. PC cells were cultured and infected with viruses. After transient transfection,\u0000 CWR22-RV1-Cas9 cells were selected by puromycin with expression of LSD1 detected by Western blot. Apart from measurement of formaldehyde production, immunoprecipitation and chromatin immunoprecipitation (ChIP) were performed, followed by ATAC-seq detection, and Western blot. The data indicated\u0000 the association between LSD1-binding sites and high levels of FOXA1. LSD1 inhibitor treatment resulted in a dramatic decline in overall FOXA1 binding, significantly reducing chromosomal accessibility and also increasing lysine-methylated FOXA1 level, but it failed to affect H3K4me2 levels\u0000 at LSD1-FOXA1 occupied sites. Overexpression of LSD1-WT obtained reverse outcome. Besides, LSD1 inhibition diminished binding of FOXA1 and restored lysine-methylation of FOXA1 in methylation-deficient cells with mutant K270R. Moreover, silencing of LSD1 suppressed CWR22-RV1 tumor growth, resulting\u0000 in increased H3K4me2 and decreased AR-FL/V7 gene expression. K270me is demethylated by LSD1. LSD1 inhibitor disrupts FOXA1 chromatin association, blocks FOXA1 K270-demethylation and hinders AR binding, thereby suppressing PC cell growth.","PeriodicalId":18318,"journal":{"name":"Materials Express","volume":" 8","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138611471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of quercetin on acute appendicitis by reduction of Caspase-1 and inflammatory factors release through Toll-like receptor 4/nuclear factor kappa-B pathway 槲皮素通过Toll样受体4/核因子kappa-B途径减少Caspase-1和炎症因子的释放对急性阑尾炎的影响
IF 0.7 4区 材料科学
Materials Express Pub Date : 2023-12-01 DOI: 10.1166/mex.2023.2551
Gang Wang, Dan Han, Qingyu Zhang
{"title":"Effect of quercetin on acute appendicitis by reduction of Caspase-1 and inflammatory factors release through Toll-like receptor 4/nuclear factor kappa-B pathway","authors":"Gang Wang, Dan Han, Qingyu Zhang","doi":"10.1166/mex.2023.2551","DOIUrl":"https://doi.org/10.1166/mex.2023.2551","url":null,"abstract":"It has been reported that, quercetin can improve body’s inflammatory response through Toll-like receptor 4/nuclear factor kappa-B (TLR4/NF-κB) signaling, thereby playing a role in treating acute appendicitis. Firstly, acute appendicitis model was established in rats,\u0000 where blank group, acute appendicitis model group, and quercetin intervention group (quercetin group) were set up to detect the effect of quercetin on acute appendicitis. In addition, the model, Toll-like receptor 4 inhibitor (TAK-242), Lipopolysaccharides (LPS), quercetin+ TAK-242, and quercetin+LPS\u0000 groups were set to assess whether quercetin reduces Caspase-1 (CASP-1) through TLR4/NF-KB signaling and regulates the release of inflammatory factors to exert the effect on treating acute appendicitis. (1) Quercetin significantly inhibited the biological effects of tissue inflammation in rats\u0000 with appendicitis and this process was related to decreased expression of TLR4 and NF-κB; (2) Quercetin also inhibited TLR4 and NF-κB expression and after using TLR4 inhibitors, the release of inflammatory factors in rat appendix tissue was controlled, especially\u0000 in the quercetin+TAK-242 group. Quercetin can significantly block the development of inflammatory response in acute appendicitis, and this process is mainly achieved by reducing inflammatory factors. In addition, quercetin can effectively inhibit TLR4/NF-κB signaling related to\u0000 anti-inflammatory effect, thereby down-regulating the expression of CASP-1, and finally inhibiting the inflammatory response of acute appendicitis.","PeriodicalId":18318,"journal":{"name":"Materials Express","volume":" 30","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138613599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of nanoscale zero-valent iron (nZVI) in remediation of heavy metal contamination in groundwater overexploitation areas 纳米级零价铁(nZVI)在地下水过度开采区重金属污染修复中的作用
IF 0.7 4区 材料科学
Materials Express Pub Date : 2023-12-01 DOI: 10.1166/mex.2023.2555
Yuan Fang, Shichang Gao, Lei Wu, Jing Wang, Chao Yang, Lijun Tang, Pengwei Su, Qi Li
{"title":"The role of nanoscale zero-valent iron (nZVI) in remediation of heavy metal contamination in groundwater overexploitation areas","authors":"Yuan Fang, Shichang Gao, Lei Wu, Jing Wang, Chao Yang, Lijun Tang, Pengwei Su, Qi Li","doi":"10.1166/mex.2023.2555","DOIUrl":"https://doi.org/10.1166/mex.2023.2555","url":null,"abstract":"This study investigates the remediation of groundwater contaminated with heavy metals in overexploited areas using a modified approach involving the use of corn plant parts to produce biochar. The biochar was modified using a hydrothermal method, employing nanoscale zero-valent iron\u0000 (nZVI) material to create a composite material for adsorbing heavy metals from water bodies. Adsorption experiments were conducted on the presence of Cr, Cu, and Zn ions in the water. The experimental investigations focused on the dosage of adsorption materials, solution pH, and stability\u0000 of the adsorption material to validate the enhanced capability of the nanoscale zero-valent iron modified biochar composite (Fe-CBC-MO) for removing and adsorbing heavy metal ions (Cu, Cr, and Zn) from water. The results indicate that the adsorption capacity follows the sequence: Cr > Zn\u0000 > Cu. Increasing the adsorbent dosage provides more adsorption sites, thereby improving the removal efficiency of heavy metals from water bodies. Considering cost-effectiveness, an optimal dosage of 0.15 g was selected. Under alkaline conditions, Cu and Zn ions precipitated significantly,\u0000 leading to sustained high removal rates of heavy metals. Correspondingly, the rate constants were also relatively high. In acidic environments, the rate constant for Cr decreased significantly due to corrosion passivation. The composite material Fe-CBC-MO exhibited remarkable removal efficiency\u0000 for all three heavy metals (Cr, Cu, Zn), demonstrating a strong capability for remediating heavy metal pollution.","PeriodicalId":18318,"journal":{"name":"Materials Express","volume":"51 4","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138622691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of casein phosphopeptide incorporation with mesoporous 58S bioactive glass on remineralization in vitro for teeth enamel regeneration 酪蛋白磷酸肽与介孔 58S 生物活性玻璃的结合对牙釉质再生体外再矿化的影响
IF 0.7 4区 材料科学
Materials Express Pub Date : 2023-12-01 DOI: 10.1166/mex.2023.2544
Lu Tang, Yu Li, Suqi Wang, Jin Yang, Zhihong Dong
{"title":"Effect of casein phosphopeptide incorporation with mesoporous 58S bioactive glass on remineralization in vitro for teeth enamel regeneration","authors":"Lu Tang, Yu Li, Suqi Wang, Jin Yang, Zhihong Dong","doi":"10.1166/mex.2023.2544","DOIUrl":"https://doi.org/10.1166/mex.2023.2544","url":null,"abstract":"Caries is the most widespread oral disease threatening human health, especially early childhood caries, traditional treatment is a big challenge in clinical. In order to prevent early enamel demineralization, casein phosphopeptides (CPPs) incorporation with mesoporous 58S bioactive\u0000 glass (M58S) was used to evaluate the remineralization enamel ability in vitro. By sol–gel method M58S was synthesized and showed good pore size and pore volume. In simulated oral fluid (SOF), 3%wt CPPs/M58S showed a better mineralized ability, remineralized layer was smooth and\u0000 dense, thickness of 20 nm for 24 h, and structure of crystals was similar to the apatite, Human oral adhesion keratinocytes cells (HOKs) can regulate expression and promoted cell proliferation and differentiation, which showed a good biocompatibility. It is expected that CPPs/M58S may be an\u0000 effective agent in the treatment of early children caries and dental allergies.","PeriodicalId":18318,"journal":{"name":"Materials Express","volume":" August","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138611349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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