Korean Circulation Journal最新文献_第3页

Exercising the Heart, Protecting the Brain: Cardiac Rehabilitation and Cognition in Heart Failure. 锻炼心脏，保护大脑：心脏康复和心力衰竭的认知。

IF 3.4 3区医学

Korean Circulation Journal Pub Date : 2026-08-12 DOI: 10.4070/kcj.2026.0340

Heesun Lee, Kyuwan Lee, Jong-Chan Youn

引用次数: 0

When Lowering LDL Is Not Enough: Confronting Residual Inflammatory Risk After Myocardial Infarction. 当降低LDL不够时：面对心肌梗死后的残余炎症风险。

IF 3.4 3区医学

Korean Circulation Journal Pub Date : 2026-08-11 DOI: 10.4070/kcj.2026.0353

Onyou Kim, Soon Jun Hong

引用次数: 0

Long-Term Impact of New-Onset Diabetes Mellitus in Hypertensive Patients. 高血压患者新发糖尿病的长期影响。

IF 3.4 3区医学

Korean Circulation Journal Pub Date : 2026-08-06 DOI: 10.4070/kcj.2026.0017

Sungjoon Park, Suhyun Kim, Ho-Gyun Shin, Kyun-Ik Park, Seung-Pyo Lee, Hee-Sun Lee, Ju-Yeun Lee, Kwang-Il Kim, Si-Hyuck Kang, Jang Hoon Lee, Ju-Hee Lee, Kye Hun Kim, Jae Yeong Cho, Jae-Hyeong Park, Sue K Park, Mina Kim, Jin Young Lee, Kwangsoo Kim, Hae-Young Lee

{"title":"Long-Term Impact of New-Onset Diabetes Mellitus in Hypertensive Patients.","authors":"Sungjoon Park, Suhyun Kim, Ho-Gyun Shin, Kyun-Ik Park, Seung-Pyo Lee, Hee-Sun Lee, Ju-Yeun Lee, Kwang-Il Kim, Si-Hyuck Kang, Jang Hoon Lee, Ju-Hee Lee, Kye Hun Kim, Jae Yeong Cho, Jae-Hyeong Park, Sue K Park, Mina Kim, Jin Young Lee, Kwangsoo Kim, Hae-Young Lee","doi":"10.4070/kcj.2026.0017","DOIUrl":"https://doi.org/10.4070/kcj.2026.0017","url":null,"abstract":"Background and objectives: Hypertension (HT) is a known risk factor for new-onset diabetes mellitus (NODM), which increases cardiovascular risk. However, the long-term impact of NODM in hypertensive patients remains unclear.Methods: We analyzed 10,057 hypertensive patients and 109,406 age- and sex-matched non-hypertensive controls from the Korean Hypertension Cohort, followed for over 10 years using National Health Insurance System-Health Screening data. Both cohorts were linked to the National Health Insurance claims database for longitudinal follow-up and outcome assessment. Cox proportional hazards models assessed NODM incidence and its association with major adverse cardiovascular events (MACE) and mortality.Results: The cumulative incidence of NODM was higher in hypertensive patients (8.9% at 2 years, 16.3% at 5 years, and 25.1% at 10 years) than in controls (1.9%, 6.5%, and 14.3%, respectively). The relative risk (RR) of NODM was highest in the first 2 years (RR, 4.55, 95% confidence interval [CI], 4.21-4.90) and remained elevated at 5 years (RR, 2.48) and 10 years (RR, 1.82). Hypertensive patients with NODM had a higher incidence of MACE or death (21.2% vs. 18.7%, RR, 1.21, 95% CI, 1.10-1.32). Most significantly, incidence of post-myocardial infarction heart failure was markedly higher (RR, 4.16, 95% CI, 1.67-10.33). In non-hypertensive individuals, NODM conferred a greater RR for stroke (1.79, 95% CI, 1.23-2.59) than in hypertensive patients.Conclusions: NODM is highly prevalent in hypertensive patients, particularly early on, and was associated with cardiovascular risk. These findings emphasize the need for early intervention to prevent NODM and its complications in hypertensive individuals.","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149025265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Systematic Review of Cardiovascular Risk Prediction Models for the Korean Population. 韩国人群心血管风险预测模型的系统评价

IF 3.4 3区医学

Korean Circulation Journal Pub Date : 2026-08-05 DOI: 10.4070/kcj.2026.0084

Jaeyong Lee, Sojung Shin, Dasom Son, Hyeok-Hee Lee, Hyeon Chang Kim, Hokyou Lee

{"title":"Systematic Review of Cardiovascular Risk Prediction Models for the Korean Population.","authors":"Jaeyong Lee, Sojung Shin, Dasom Son, Hyeok-Hee Lee, Hyeon Chang Kim, Hokyou Lee","doi":"10.4070/kcj.2026.0084","DOIUrl":"https://doi.org/10.4070/kcj.2026.0084","url":null,"abstract":"Introduction of cardiovascular disease (CVD) risk prediction models is necessary for optimal risk stratification for CVD prevention. While several Korean models have been developed, their comprehensive and comparative assessment remain limited. We aimed to systematically review CVD risk prediction models developed for the Korean population.We performed a comprehensive literature search across PubMed, Embase, KoreaMed, and Kmbase databases up to September 2025. Two authors independently screened the titles, abstracts, and full texts of retrieved articles. Information on model characteristics was extracted using a standardized form, and the quality of the models was assessed using the Prediction model Risk Of Bias Assessment Tool. A total of 2,399 articles were initially identified, of which 9 were included in the systematic review. The prediction horizon of the models ranged from 3 to 12 years, with 6 models predicting 10-year risk. All 9 models included established risk factors such as age, smoking status, systolic blood pressure, and total cholesterol as risk predictors. Five models predicted a composite of myocardial infarction (MI) and stroke, 3 models predicted stroke, and one model predicted MI. Internal validation was performed for all models, with discriminatory performance reported across all models and calibration measures reported in 6 models. None had undergone adequate external validation. Nine Korean CVD risk prediction models were identified, all lacking adequate external validation. Validated CVD risk prediction models are needed to optimize risk-based CVD prevention in Korea.","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149025279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term Impact of Residual Inflammatory Risk in Acute Myocardial Infarction Patients Treated With Percutaneous Coronary Intervention Who Achieved Optimal Lipid Control. 经皮冠状动脉介入治疗获得最佳脂质控制的急性心肌梗死患者残留炎症风险的长期影响

IF 3.4 3区医学

Korean Circulation Journal Pub Date : 2026-08-05 DOI: 10.4070/kcj.2025.0469

Sangho Hyun, Kyung An Kim, Sang Hyun Kim, Myunhee Lee, Sungmin Lim, Byung-Hee Hwang, Eun Ho Choo, Jin-Jin Kim, Ik Jun Choi, Chan Joon Kim, Mahn-Won Park, Kiyuk Chang, Kwan Yong Lee

{"title":"Long-term Impact of Residual Inflammatory Risk in Acute Myocardial Infarction Patients Treated With Percutaneous Coronary Intervention Who Achieved Optimal Lipid Control.","authors":"Sangho Hyun, Kyung An Kim, Sang Hyun Kim, Myunhee Lee, Sungmin Lim, Byung-Hee Hwang, Eun Ho Choo, Jin-Jin Kim, Ik Jun Choi, Chan Joon Kim, Mahn-Won Park, Kiyuk Chang, Kwan Yong Lee","doi":"10.4070/kcj.2025.0469","DOIUrl":"https://doi.org/10.4070/kcj.2025.0469","url":null,"abstract":"Background and objectives: This study aimed to evaluate the prognostic impact of high residual inflammatory risk (RIR) in patients with acute myocardial infarction (AMI) who underwent percutaneous coronary intervention (PCI) and achieved optimal low-density lipoprotein cholesterol (LDL-C) control.Methods: A retrospective analysis was conducted on successfully revascularized AMI patients from a large, prospective, multi-center PCI registry between 2004 and 2014. Patients with LDL-C ≤70 mg/dL at 1-year follow up and serial high-sensitivity C-reactive protein (hsCRP) measurements at baseline and 1 year were included. High RIR was defined as hsCRP >2 mg/L at 1 year. The primary endpoint was all-cause mortality, and secondary endpoints were major adverse cardiac and cerebrovascular events (MACCE).Results: Of the 661 patients, 129 (19.5%) had high RIR. Over a median follow up of 5.3 years, the high RIR group had significantly higher mortality rates (43.1 per 1,000 patient-years) compared to the low RIR group (10.9 per 1,000 patient-years; p<0.001). After multivariable adjustment, high RIR remained independently associated with increased mortality (adjusted hazard ratio [HR], 3.41; 95% confidence interval [CI], 1.80-6.45; p<0.001) and a higher risk of MACCE (adjusted HR, 3.08; 95% CI, 1.90-4.99; p<0.001). The associations between high RIR and adverse outcomes were also consistent in the subgroup with LDL-C ≤55 mg/dL.Conclusions: In stabilized AMI patients with optimal LDL-C control after PCI, high RIR is a significant prognostic factor for adverse events. Reducing residual inflammation may improve long-term outcomes following PCI in these patients.Trial registration: ClinicalTrials.gov Identifier: NCT02806102.","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149025205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insights Into Atrial Arrhythmias After Atrial Septal Defect Closure. 房间隔缺损闭合后心房心律失常的认识。

IF 3.4 3区医学

Korean Circulation Journal Pub Date : 2026-08-04 DOI: 10.4070/kcj.2026.0264

Miyako Igarashi, Tomoko Ishizu

引用次数: 0

Reconsidering Radial Strategy in Cardiogenic Shock. 心源性休克放射治疗策略的再思考。

IF 3.4 3区医学

Korean Circulation Journal Pub Date : 2026-08-01 Epub Date: 2026-04-20 DOI: 10.4070/kcj.2026.0101

Namkyun Kim, Yongcheol Kim

引用次数: 0

Efficacy of Antimicrobial Envelopes in Preventing Cardiac Implantable Electronic Device Infection: Systematic Review and Meta-Analysis. 抗菌膜预防心脏植入式电子设备感染的效果：系统回顾和meta分析。

IF 3.4 3区医学

Korean Circulation Journal Pub Date : 2026-08-01 Epub Date: 2026-02-24 DOI: 10.4070/kcj.2025.0342

Akanksha Mahajan, Ojas Mehta, Rhonda Stuart, Christopher Robson

{"title":"Efficacy of Antimicrobial Envelopes in Preventing Cardiac Implantable Electronic Device Infection: Systematic Review and Meta-Analysis.","authors":"Akanksha Mahajan, Ojas Mehta, Rhonda Stuart, Christopher Robson","doi":"10.4070/kcj.2025.0342","DOIUrl":"10.4070/kcj.2025.0342","url":null,"abstract":"Background and objectives: Cardiac implantable electronic device (CIED) infections remain a significant complication of increasingly common CIED procedures. This systematic review aims to evaluate the efficacy of antibiotic eluting envelopes (AEEs) in preventing CIED infections.Methods: A systematic search of MEDLINE, CINAHL, Embase, Scopus, and Cochrane Library was conducted from inception to September 2024. Human studies evaluating TYRX AEE or CanGaroo envelopes hydrated in antibiotics were eligible. Studies on CanGaroo envelope were excluded from meta-analysis. RoB 2 and ROBINS-I tools were used to assess risk of bias.Results: Fourteen studies and 87,184 patients were included. AEE use did not result in statistically significant reduction in odds of any CIED infection over entire study duration (odds ratio [OR], 0.73; 95% confidence interval [CI], 0.49-1.08) or within 12 months (OR, 0.85; 95% CI, 0.62-1.18), major CIED infection over entire study duration (OR, 0.73; 95% CI, 0.44-1.22) or within 12 months (OR, 0.79; 95% CI, 0.46-1.37), minor CIED infection (OR, 0.75; 95% CI, 0.48-1.18) or mortality (OR, 1.07; 95% CI, 0.60-1.88). However, in high infection risk patients, AEE use was associated with reduction in any infections over entire study duration (OR, 0.66; 95% CI, 0.45-0.97) and within 12 months (OR, 0.73; 95% CI, 0.56-0.95).Conclusions: Limitations of this review include group difference and scarcity of data regarding comorbidities in some studiesk. Overall, AEE use is not effective in reducing odds of CIED infection, although it may benefit high infection risk patients.Trial registration: International Register of Prospective Systematic Reviews (PROSPERO) Identifier: CRD42024588950.","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":"713-728"},"PeriodicalIF":3.4,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13442981/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147674377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic Impact of Mitral Annular Calcification and Aortic Arch Calcification in Severe Aortic Stenosis Patients Undergoing Aortic Valve Replacement. 重度主动脉瓣狭窄患者行主动脉瓣置换术二尖瓣环钙化和主动脉弓钙化对预后的影响。

IF 3.4 3区医学

Korean Circulation Journal Pub Date : 2026-08-01 Epub Date: 2026-02-20 DOI: 10.4070/kcj.2025.0266

Seok Hyun Kim, Soo Yong Lee, Jin Hee Choi, Min Ku Chon, Ki Won Hwang, Jeongsu Kim, Yong Hyun Park, June Hong Kim, Kook Jin Chun, Mi Hee Lim, Chee-Hoon Lee, Min Ho Ju, Hyung Gon Je, Sang Hyun Lee

{"title":"Prognostic Impact of Mitral Annular Calcification and Aortic Arch Calcification in Severe Aortic Stenosis Patients Undergoing Aortic Valve Replacement.","authors":"Seok Hyun Kim, Soo Yong Lee, Jin Hee Choi, Min Ku Chon, Ki Won Hwang, Jeongsu Kim, Yong Hyun Park, June Hong Kim, Kook Jin Chun, Mi Hee Lim, Chee-Hoon Lee, Min Ho Ju, Hyung Gon Je, Sang Hyun Lee","doi":"10.4070/kcj.2025.0266","DOIUrl":"10.4070/kcj.2025.0266","url":null,"abstract":"Background and objectives: Patients with severe aortic stenosis (AS) often have mitral annular calcification (MAC) and aortic arch calcification (AAC). We investigated the clinical significance of a MAC and extensive AAC in patients with AS requiring aortic valve replacement (AVR).Methods: We retrospectively analyzed 636 patients with severe AS who underwent AVR (surgical or transcatheter) at our institution. Preoperative echocardiography and computed tomography were used to identify MAC, and chest radiographs were reviewed for AAC.Results: Of the 636 patients, 133 (20.9%) had MAC, while 156 (24.5%) had extensive AAC (≥180°). Patients with MAC were older and more often female, with higher Society of Thoracic Surgeons scores and greater comorbidities. Over a median follow-up of 5.2 years, 157 patients (24.7%) died. In univariate analysis, the presence of any MAC and extensive AAC was associated with significantly higher mortality. In multivariable analysis, however, neither was an independent predictor of mortality. Instead, age, male sex, diabetes mellitus, chronic kidney disease (eGFR <60 mL/min/1.73 m²), and dialysis emerged as independent risk factors.Conclusions: MAC and extensive AAC identify a subset of patients with severe AS who are older and have more comorbid disease. Management of such patients should focus on optimizing overall risk factors, and the presence of MAC or AAC alone should not exclude patients from life-saving AVR therapies.","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":"732-746"},"PeriodicalIF":3.4,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13442986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147499409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Consistency Matters: Clopidogrel Monotherapy as Long-term Secondary Prevention Following Percutaneous Coronary Intervention. 一致性问题：氯吡格雷单药治疗作为经皮冠状动脉介入术后的长期二级预防。

IF 3.4 3区医学

Korean Circulation Journal Pub Date : 2026-08-01 Epub Date: 2026-04-28 DOI: 10.4070/kcj.2026.0092

Woong Gil Choi

引用次数: 0