Danbi Ku, Youn Huh, Wonsock Kim, Jae-Min Park, Jung Yeon Chin, Jung Hwan Kim, Young Sik Kim, Seo Young Kang
{"title":"Relationship Between Food Insecurity and Poor Cardiovascular Health in Korean Adults.","authors":"Danbi Ku, Youn Huh, Wonsock Kim, Jae-Min Park, Jung Yeon Chin, Jung Hwan Kim, Young Sik Kim, Seo Young Kang","doi":"10.4070/kcj.2025.0081","DOIUrl":"https://doi.org/10.4070/kcj.2025.0081","url":null,"abstract":"<p><strong>Background and objectives: </strong>The association between food insecurity and cardiovascular health (CVH) in Korean adults remains unclear. This study aimed to investigate the association between food insecurity and CVH in Korean adults.</p><p><strong>Methods: </strong>This study included 14,034 adults aged ≥19 years in the Korea National Health and Nutrition Examination Survey 2019-2021. CVH was defined using the American Heart Association's Life's Simple 7 framework, including smoking status, physical activity, diet, body mass index, total cholesterol, blood pressure, and fasting glucose. Participants were categorized into the food secure or food insecure group based on their survey scores. Multivariate logistic regression analysis was performed to calculate the association between food insecurity and poor CVH.</p><p><strong>Results: </strong>Among the participants, 4.0% belonged to the food insecure group and 96.0% belonged to the food secure group, and 15.3%, 61.4%, and 23.3% of the participants had ideal, intermediate, and poor CVH, respectively. In the multivariate analysis, the odds ratio (95% confidence interval) for poor CVH was 1.32 (1.06-1.64) in food insecure group compared to food secure group. The odds for poor CVH increased as food security status aggravated (p for trend <0.05). Moreover, food insecure group had higher odds of poor status in the following CVH components: smoking and blood pressure.</p><p><strong>Conclusions: </strong>Food insecurity is associated with poor CVH in Korean adults. Specifically, it is associated with current smoking and high blood pressure. Improving food insecurity may help prevent poor CVH in Korea.</p>","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145225477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnosis and Management of Statin-Associated Muscle Symptoms.","authors":"Jung-Joon Cha, Soon Jun Hong","doi":"10.4070/kcj.2025.0285","DOIUrl":"https://doi.org/10.4070/kcj.2025.0285","url":null,"abstract":"<p><p>Statin-associated muscle symptoms (SAMS) are a common clinical challenge that often lead to poor adherence or discontinuation of statin therapy, thereby undermining its well-established cardiovascular benefits. This review explores the current understanding of the epidemiology, pathophysiology, clinical presentation, and diagnostic considerations of SAMS, with a particular focus on distinguishing true statin intolerance from nonspecific muscle complaints. We discuss evidence-based management strategies, including statin dose adjustment, rechallenge protocols, and the application of alternative lipid-lowering therapies such as ezetimibe, PCSK9 inhibitors, and bempedoic acid. Recent clinical trials support the efficacy and tolerability of combination therapy with moderate-intensity statins and ezetimibe, particularly in high-risk patients. A pragmatic, patient-centered approach is crucial for maintaining lipid-lowering therapy, minimizing adverse effects, and effectively reducing cardiovascular risk.</p>","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145225127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Uncovering a Distinct Hormonal Phenotype in Primary Hypertension: Rethinking the Role of Renin and Aldosterone Measurement for Hypertension Management.","authors":"Kwang-Il Kim","doi":"10.4070/kcj.2025.0293","DOIUrl":"https://doi.org/10.4070/kcj.2025.0293","url":null,"abstract":"","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145225553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Suboptimal Cardiovascular Health in Korea: Insights From the First Application of Life's Essential 8.","authors":"Hack-Lyoung Kim","doi":"10.4070/kcj.2025.0152","DOIUrl":"10.4070/kcj.2025.0152","url":null,"abstract":"","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":"753-755"},"PeriodicalIF":3.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12314061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144333378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sang-Suk Choi, Jin Jung, Sung-Ho Her, Kyunyeon Kim, Kyuho Kim, Jae-Seung Yun, Seung-Hyun Ko, Kyu-Na Lee, Kyung Do Han, Kyeongju Yoon, Geumhee Sim, Yujeong Park, Rihyang Kim, Nayoon Jeong
{"title":"Korean Cardiovascular Health Status Assessed by Life's Essential 8 in Korean Adult Population: Based on Data From the Korean National Health and Nutrition Examination Survey 2014-2021.","authors":"Sang-Suk Choi, Jin Jung, Sung-Ho Her, Kyunyeon Kim, Kyuho Kim, Jae-Seung Yun, Seung-Hyun Ko, Kyu-Na Lee, Kyung Do Han, Kyeongju Yoon, Geumhee Sim, Yujeong Park, Rihyang Kim, Nayoon Jeong","doi":"10.4070/kcj.2024.0411","DOIUrl":"10.4070/kcj.2024.0411","url":null,"abstract":"<p><strong>Background and objectives: </strong>Cardiovascular disease is a leading cause of mortality globally and in South Korea. The American Heart Association (AHA) developed Life's Essential 8 (LE8) to evaluate cardiovascular health (CVH) through 8 metrics. However, LE8 has not been studied in the Korean population. This study aims to assess CVH in Korean adults using LE8 metrics and Korea National Health and Nutrition Examination Survey (KNHANES) data.</p><p><strong>Methods: </strong>This cross-sectional study analyzed 35,117 adults from KNHANES (2014-2021). CVH scores were calculated across 8 metrics (diet, physical activity [PA], nicotine exposure, sleep health, body mass index, blood lipids, blood glucose, and blood pressure) and classified as high (80-100), moderate (50-79), or low (0-49). Demographic, socioeconomic, and clinical characteristics were compared across categories.</p><p><strong>Results: </strong>Among 35,117 participants (weighted population: 30,544,496; 51.6% women), the mean CVH score was 63.1±0.1, with women scoring higher than men (66.9 vs. 59.1; p<0.001). Only 12.3% achieved high CVH, while 17.7% were classified as low. Diet and PA had the lowest scores, while sleep and blood glucose scored highest. Women demonstrated higher scores than men except in PA. Low CVH was associated with older age (≥65 years: 19.5% low vs. 4.4% in 19-39 years), lower socioeconomic status (68.2% low vs. 31.8% high education), and chronic diseases (e.g., hypertension, diabetes).</p><p><strong>Conclusions: </strong>This first application of AHA's LE8 metrics to Korean adults revealed suboptimal CVH with significant disparities by age, gender, socioeconomic status, and chronic diseases, emphasizing the need for targeted interventions.</p>","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":"736-752"},"PeriodicalIF":3.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12314067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144333358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Min-Jung Cho, Soo-Jin Kim, Miyoung Choi, Joo Sung Lee, Kyung Jin Oh, Hee Jung Choi, Gwang-Jun Choi, Jae Yoon Na, Jae Hee Seol, Jin Young Song
{"title":"Pulmonary Vasodilator Therapy in Patients With Fontan Circulation: A Meta-Analysis.","authors":"Min-Jung Cho, Soo-Jin Kim, Miyoung Choi, Joo Sung Lee, Kyung Jin Oh, Hee Jung Choi, Gwang-Jun Choi, Jae Yoon Na, Jae Hee Seol, Jin Young Song","doi":"10.4070/kcj.2024.0378","DOIUrl":"10.4070/kcj.2024.0378","url":null,"abstract":"<p><strong>Background and objectives: </strong>The effect of pulmonary vasodilator therapy on patients with Fontan circulation remains unclear. This study aims to assess its impact on exercise capacity and hemodynamic parameters in this population.</p><p><strong>Methods: </strong>We searched PubMed, Embase, and the Cochrane Library for relevant studies up to November 2023. Pooled outcomes were used to evaluate the efficacy of pulmonary vasodilators in Fontan patients.</p><p><strong>Results: </strong>A total of 18 studies with 667 patients were included. Exercise capacity was assessed in 14 studies (526 patients). Pulmonary vasodilator therapy improved oxygen consumption anaerobic threshold (VO₂AT; MD, 1.12 mL/min/kg; 95% CI, 0.35 to 1.89; p=0.004) and Ve/VCO₂ slope (MD, -1.14; 95% CI, -1.97 to -0.31; p=0.007) during exercise. No significant differences were found among drug classes regarding peak oxygen consumption, Ve/VCO₂, or VO₂AT. Invasive hemodynamics were evaluated in 6 studies (126 patients). Pulmonary vasodilators significantly reduced mean pulmonary arterial pressure (MD, -2.28 mmHg; p=0.02), pulmonary vascular resistance (MD, -0.91 WU*m²; p=0.01), and improved pulmonary flow (MD, 0.46 L/min/m²; p=0.02).</p><p><strong>Conclusions: </strong>Pulmonary vasodilator therapy appears beneficial for exercise capacity and pulmonary hemodynamics in Fontan patients. More randomized controlled trials are needed to confirm these findings.</p>","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":"721-732"},"PeriodicalIF":3.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12314064/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hye Bin Gwag, Su Hyun Lee, Tae-Hoon Kim, Seung-Jung Park, Juwon Kim, Ju Youn Kim, Kyoung-Min Park, Young Keun On, Boyoung Joung
{"title":"Real-World Effectiveness of Adaptive Left Ventricular-Only Pacing for Cardiac Resynchronization Therapy in Asian Population: Insights From the K-Adaptive CRT Study.","authors":"Hye Bin Gwag, Su Hyun Lee, Tae-Hoon Kim, Seung-Jung Park, Juwon Kim, Ju Youn Kim, Kyoung-Min Park, Young Keun On, Boyoung Joung","doi":"10.4070/kcj.2024.0442","DOIUrl":"10.4070/kcj.2024.0442","url":null,"abstract":"<p><strong>Background and objectives: </strong>Conflicting results have been reported regarding the efficacy of left ventricular-only pacing (LVP) synchronized with intrinsic right ventricular conduction (adaptive LVP) for cardiac resynchronization therapy (CRT) in Western heart failure (HF) populations. We compared adaptive LVP with conventional biventricular pacing (BVP) in Asian HF patients.</p><p><strong>Methods: </strong>The K-adaptive CRT study, the largest adaptive CRT study to date in Asian HF patients, evaluated 368 HF patients who received CRT devices with an adaptive pacing algorithm between September 2013 and March 2020 from 25 tertiary hospitals in Korea. Patients were classified into 3 groups according to their pacing configuration: adaptive LVP (n=160), adaptive BVP (n=86), and conventional BVP groups (n=122). Primary outcome was the composite of all-cause death, HF hospitalization, and appropriate implantable cardioverter-defibrillator therapy.</p><p><strong>Results: </strong>During the mean 3.7-year follow-up period, incidence of the primary outcome was significantly lower in the adaptive LVP group than the conventional BVP group (hazard ratio [HR], 0.56; 95% confidence interval [CI], 0.36-0.85; p=0.007), while outcomes in the adaptive and conventional BVP groups were comparable. Patients with higher LVP% (≥65%) showed a further reduction in relative risk of the primary outcome (HR, 0.41; 95% CI, 0.22-0.76; p=0.005). Adaptive LVP was consistently associated with a lower risk of clinical outcomes in various subgroup analyses, and was identified as an independent factor for favorable long-term outcomes.</p><p><strong>Conclusions: </strong>The K-adaptive CRT study suggests that adaptive LVP is associated with better clinical outcomes than conventional BVP in Asian HF patients.</p>","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":"688-700"},"PeriodicalIF":3.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12314062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144333375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Woochan Kwon, Ki Hong Choi, Young Bin Song, Joo Myung Lee, Taek Kyu Park, Jeong Hoon Yang, Joo-Yong Hahn, Seung-Hyuk Choi, Jae-Hwan Lee, Min Chul Kim, Hyun-Jong Lee, Hyeon-Cheol Gwon
{"title":"Effect of Operator Experience Performing Rotational Atherectomy on Clinical Outcomes After Percutaneous Coronary Intervention.","authors":"Woochan Kwon, Ki Hong Choi, Young Bin Song, Joo Myung Lee, Taek Kyu Park, Jeong Hoon Yang, Joo-Yong Hahn, Seung-Hyuk Choi, Jae-Hwan Lee, Min Chul Kim, Hyun-Jong Lee, Hyeon-Cheol Gwon","doi":"10.4070/kcj.2024.0318","DOIUrl":"10.4070/kcj.2024.0318","url":null,"abstract":"<p><strong>Background and objectives: </strong>Rotational atherectomy (RA) is a technique used to ablate calcified plaques. There is speculation that operators' experience with RA could play a role in the outcomes.</p><p><strong>Methods: </strong>From December 2015 to April 2020, patients with calcified coronary lesions requiring percutaneous coronary intervention (PCI) with RA were enrolled in a prospective, multicenter, observational registry. The patients were divided into two groups based on the number of RAs performed by their operator in the past. A propensity score matching was done for a sensitivity analysis. The primary outcome was a composite of cardiac death, myocardial infarction, and target vessel revascularization at 1 year.</p><p><strong>Results: </strong>A total of 497 patients were enrolled in the study. The calculated cutoff number of RA-PCI between the two groups was 82 cases. The more experienced group underwent PCI with less fluoroscopy time (less experienced vs. more experienced, 38.8 vs. 30.0 minutes, p<0.001), and more frequent intravascular imaging (54.6% vs. 69.0%, p=0.012). The primary outcome did not differ significantly between the groups (5.2% vs. 7.3%, hazard ratio, 1.46; 95% confidence interval [CI], 0.57-3.74; p=0.433). No significant difference in the incidence of complications was observed between the groups (5.5% vs. 7.0%, odds ratio, 1.38; 95% CI, 0.57-3.04; p=0.526). Similar results were observed in the propensity-score matched population.</p><p><strong>Conclusions: </strong>In PCI using RA for calcified lesions, the composite outcome of cardiac death, myocardial infarction, and target vessel revascularization at 1 year was not significantly different according to RA experience among operators.</p>","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":"672-684"},"PeriodicalIF":3.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12314066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144333354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Exercise Capacity in Fontan Patients and Effects of Pulmonary Vasodilators.","authors":"Sung Hye Kim","doi":"10.4070/kcj.2025.0163","DOIUrl":"10.4070/kcj.2025.0163","url":null,"abstract":"","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":"733-735"},"PeriodicalIF":3.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12314058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144591572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}