Korean Circulation Journal最新文献

{"title":"Intravascular Ultrasound-Guided Percutaneous Coronary Intervention for Severely Calcified Lesions Requiring Rotational Atherectomy.","authors":"Duck-Hyun Jang, Je Sang Kim, Sung-Ho Her, Kyusup Lee, Sang-Hoon Cho, Ik-Jun Choi, Jae-Hwan Lee, Jang-Hoon Lee, Sang-Rok Lee, Pil-Hyung Lee, Seung-Whan Lee, Ki-Dong Yoo, Kyeong Ho Yun, Young Jin Choi, Tae-Hoon Kim, Ho-Jun Jang, Ha Wook Park, Chi-Hoon Kim, Hyun-Jong Lee","doi":"10.4070/kcj.2025.0255","DOIUrl":"https://doi.org/10.4070/kcj.2025.0255","url":null,"abstract":"<p><strong>Background and objectives: </strong>Intravascular ultrasound (IVUS) is an invaluable tool for accurate lesion assessment and optimal stent implantation during complex coronary interventions. This study evaluated the impact of IVUS guidance on the long-term clinical outcomes of patients undergoing percutaneous coronary intervention (PCI) for severely calcified lesions requiring rotational atherectomy (RA).</p><p><strong>Methods: </strong>Between January 2010 and October 2019, 511 patients from nine tertiary centers in South Korea who underwent PCI with RA using second-generation drug-eluting stents were enrolled. The primary endpoint was a composite of cardiac death or myocardial infarction (MI).</p><p><strong>Results: </strong>IVUS was performed in 241 (47.2%) patients. Compared with the angiography-guided PCI (A-GP) group, the IVUS-guided PCI (I-GP) group had a higher prevalence of the left main disease (23.7% vs. 5.9%; p<0.001), larger stents (3.1 mm vs. 2.9 mm; p<0.001), longer stents (72 mm vs. 61 mm; p<0.001), and more frequent post-dilation (85.4% vs. 71.9%; p<0.001). Within a median follow-up of 20 (9-39) months, compared with the A-GP group, the I-GP group had a significantly lower risk of cardiac death or MI (7.0% vs. 11.2%; hazard ratio [HR], 0.481; 95% confidence interval [CI], 0.254-0.908; p=0.024). After adjusting for potential confounders with inverse probability of treatment weighting, the I-GP group still had a significantly lower risk of cardiac death or MI, and cardiac death (HR, 0.442; 95% CI, 0.226-0.865; p=0.017, and HR, 0.413; 95% CI, 0.181-0.944; p=0.036).</p><p><strong>Conclusions: </strong>IVUS guidance is likely to improve long-term clinical outcomes in patients undergoing PCI with RA for severely calcified lesions.</p>","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147674374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Impact of Mitral Annular Calcification and Aortic Arch Calcification in Severe Aortic Stenosis Patients Undergoing Aortic Valve Replacement.","authors":"Seok Hyun Kim, Soo Yong Lee, Jin Hee Choi, Min Ku Chon, Ki Won Hwang, Jeongsu Kim, Yong Hyun Park, June Hong Kim, Kook Jin Chun, Mi Hee Lim, Chee-Hoon Lee, Min Ho Ju, Hyung Gon Je, Sang Hyun Lee","doi":"10.4070/kcj.2025.0266","DOIUrl":"https://doi.org/10.4070/kcj.2025.0266","url":null,"abstract":"<p><strong>Background and objectives: </strong>Patients with severe aortic stenosis (AS) often have mitral annular calcification (MAC) and aortic arch calcification (AAC). We investigated the clinical significance of a MAC and extensive AAC in patients with AS requiring aortic valve replacement (AVR).</p><p><strong>Methods: </strong>We retrospectively analyzed 636 patients with severe AS who underwent AVR (surgical or transcatheter) at our institution. Preoperative echocardiography and computed tomography were used to identify MAC, and chest radiographs were reviewed for AAC.</p><p><strong>Results: </strong>Of the 636 patients, 133 (20.9%) had MAC, while 156 (24.5%) had extensive AAC (≥180°). Patients with MAC were older and more often female, with higher Society of Thoracic Surgeons scores and greater comorbidities. Over a median follow-up of 5.2 years, 157 patients (24.7%) died. In univariate analysis, the presence of any MAC and extensive AAC was associated with significantly higher mortality. In multivariable analysis, however, neither was an independent predictor of mortality. Instead, age, male sex, diabetes mellitus, chronic kidney disease (eGFR <60 mL/min/1.73 m²), and dialysis emerged as independent risk factors.</p><p><strong>Conclusions: </strong>MAC and extensive AAC identify a subset of patients with severe AS who are older and have more comorbid disease. Management of such patients should focus on optimizing overall risk factors, and the presence of MAC or AAC alone should not exclude patients from life-saving AVR therapies.</p>","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147499409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Implications and Evolution of Significant Tricuspid Regurgitation in Patients Undergoing Left Ventricular Assist Device Implantation.","authors":"Heayoung Shin, Darae Kim, David Hong, Ji Hyun Cha, Yang Hyun Cho, Jeong Hoon Yang, Jin-Oh Choi","doi":"10.4070/kcj.2025.0260","DOIUrl":"https://doi.org/10.4070/kcj.2025.0260","url":null,"abstract":"<p><strong>Background and objectives: </strong>Tricuspid regurgitation (TR) is common in advanced heart failure patients undergoing left ventricular assist device (LVAD) implantation, yet its independent prognostic value and post-LVAD trajectory remain uncertain.</p><p><strong>Methods: </strong>This retrospective single-center study included 178 patients who underwent LVAD implantation without concomitant tricuspid valve intervention (TVI) between 2012 and 2024. Patients were stratified based on preoperative echocardiography into non-significant TR (n=141) and significant (≥ moderate) TR (n=37). Primary outcomes were early right ventricular (RV) failure, all-cause mortality and heart failure hospitalization.</p><p><strong>Results: </strong>Significant baseline TR independently predicted early RV failure (odds ratio, 2.38; 95% confidence interval, 1.04 to 5.70; p=0.041), but was not associated with long-term outcomes, including all-cause mortality or heart failure hospitalization. During follow-up, TR severity improved in 60% of patients and most patients achieved hemodynamic optimization regardless of baseline TR severity. Functional recovery was observed in both groups, with a greater tendency of 6-minute walk improvement in patients with significant TR (p=0.057).</p><p><strong>Conclusions: </strong>Baseline moderate-to-severe TR predicts early RV failure but not long-term adverse outcomes following LVAD implantation. Most patients experience spontaneous TR improvement and achieve similar hemodynamic optimization regardless of baseline TR severity. These findings suggest LVAD support alone promotes RV reverse remodeling without requiring routine concomitant TVI.</p>","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147499367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When Cancer Survival Improves, the Heart Becomes the Next Frontier.","authors":"Jin Joo Park","doi":"10.4070/kcj.2025.0534","DOIUrl":"https://doi.org/10.4070/kcj.2025.0534","url":null,"abstract":"","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147499518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knockdown of ARID1A Protects H9c2 Cells Against Hypoxia/Reoxygenation (H/R)-Induced Injury by Targeting SOX9.","authors":"Pingfeng Wang, Xiaoyu Chen, Yimin Shu, Xuesi Chen","doi":"10.4070/kcj.2025.0296","DOIUrl":"https://doi.org/10.4070/kcj.2025.0296","url":null,"abstract":"<p><strong>Background and objectives: </strong>Hypoxia/reoxygenation (H/R) injury is a major contributor to cardiac damage. The role of AT-rich interaction domain 1A (ARID1A) in cardiomyocyte H/R injury and its underlying mechanisms remain unclear.</p><p><strong>Methods: </strong>An H/R injury model was established using H9c2 cardiomyoblasts. Key assessments included cell viability (cell counting kit-8), apoptosis (Terminal deoxynucleotidyl transferase dUTP Nick End Labeling), DNA fragmentation, inflammatory cytokine levels (interleukin [IL]-1β, IL-6, IL-18), cardiac injury markers (creatine kinase-MB [CK-MB], cardiac troponin-I [cTn-I]), oxidative stress markers (lactate dehydrogenase [LDH] release, reactive oxygen species [ROS], glutathione peroxidase [GSH-Px], superoxide dismutase [SOD] activity), pyroptosis marker expression (NLR family pyrin domain containing 3 [NLRP3], caspase-1, gasdermin D [GSDMD]; Western blot), and ARID1A-SOX9 interaction (co-immunoprecipitation).</p><p><strong>Results: </strong>H/R significantly upregulated ARID1A and SOX9 expression in H9c2 cells. ARID1A knockdown effectively attenuated H/R-induced damage, including improved cell viability, reduced apoptosis and DNA fragmentation, suppressed pro-inflammatory cytokine release (IL-1β, IL-6, IL-18), lowered CK-MB and cTn-I levels, decreased LDH release and ROS generation, enhanced antioxidant enzyme activity (GSH-Px, SOD), and reduced expression of pyroptosis markers (NLRP3, caspase-1, GSDMD). Mechanistically, ARID1A physically bound to SOX9 and promoted its expression. Crucially, the protective effects of si-ARID1A against H/R injury (apoptosis, inflammation, oxidative stress, pyroptosis) were consistently reversed by SOX9 overexpression.</p><p><strong>Conclusions: </strong>ARID1A is upregulated during H/R injury and exacerbates cardiomyocyte damage by promoting apoptosis, inflammation, oxidative stress, and pyroptosis. ARID1A exerts its effects by binding to and positively regulating the expression of SOX9. Targeting the ARID1A/SOX9 axis represents a potential therapeutic strategy for mitigating H/R-induced cardiac injury.</p>","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147499419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Valvulitis Matters: Linking Mitral Regurgitation to Inflammatory Burden in Kawasaki Disease.","authors":"Ja-Kyoung Yoon","doi":"10.4070/kcj.2025.0495","DOIUrl":"https://doi.org/10.4070/kcj.2025.0495","url":null,"abstract":"","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147499515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporal Trend of Cardiovascular Disease Burden Among Cancer Patients Between 2005 and 2022: Nationwide Population-Based Cohort Study in South Korea.","authors":"Iksung Cho, Seonhwa Lee, Jaehyeong Cho, Hasung Kim, Jungkuk Lee, Hui-Jeong Hwang, Eun Jeong Cho, Hee Jun Kim, Seong-Mi Park, Sung-Eun Kim, Yun-Gyoo Lee, Mi-Hyang Jung, Jong-Chan Youn, Chan Seok Park, Chi Young Shim, Woo-Baek Chung, Yul Hwangbo, Ju-Hee Lee, Jae Gyung Kim, Seng Chan You, Il Suk Sohn","doi":"10.4070/kcj.2025.0171","DOIUrl":"https://doi.org/10.4070/kcj.2025.0171","url":null,"abstract":"<p><strong>Background and objectives: </strong>Comprehensive data on the changing landscape of cardiovascular disease (CVD) burden in cancer patients remains limited. We aimed to analyze the temporal trend in the burden of CVD among cancer patients.</p><p><strong>Methods: </strong>Using a nationwide administrative claims database in Korea, we analyzed 1,322,502 adults (aged ≥18) newly diagnosed with cancer (2005-2022). The primary outcomes were: 1) temporal trends in CVD incidence, including ischemic heart disease (IHD), heart failure (HF), and stroke; and 2) cause-specific mortality trends, focusing on cancer and CVD-related deaths. Both crude and age-standardized rates were calculated for CVD incidence and mortality.</p><p><strong>Results: </strong>The 1-year age-standardized cancer mortality rate showed a substantial decline from 134.0 to 76.3 per 1,000 person-years. While the age-standardized 1-year CVD incidence initially decreased from 91.7 to 50.6 per 1,000 person-years (2005-2014), this improvement plateaued and showed an upward trend thereafter. Analysis of CVD subtypes revealed divergent patterns: age-standardized IHD incidence declined, while HF incidence rose by 136%, 52%, and 37% at 1-, 3-, and 5-year follow-ups. Despite improvements in cancer mortality, the proportion of deaths attributed to CVD increased from 1.0% to 1.5% at 1-year, corresponding to a 50% relative rise and showed a similar upward trend at 5-year follow-up, with HF emerging as an increasingly cause of cardiovascular death (increasing from 10.8% to 26.3% of CVD mortality).</p><p><strong>Conclusions: </strong>While cancer-specific mortality has improved significantly, cardiovascular mortality remains a growing concern, due to the increasing burden of HF in cancer patients. Ongoing CVD pattern surveillance in cancer patients is crucial for targeted interventions and prevention.</p>","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147499480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness and Safety of COVID-19 Vaccination in Patients With Heart Failure: A Nationwide Retrospective Cohort Study.","authors":"Kyeong-Hyeon Chun, Chan Joo Lee, Haeyong Park, Wooyong Jeong, Kwon-Duk Seo, Jiwon Seo, Jaewon Oh, Hyeongsoo Kim, Ji-Yong Jang, Hancheol Lee, Jong-Kwan Park, Seungjin Oh, Se-Jung Yoon, Seok-Min Kang","doi":"10.4070/kcj.2024.0429","DOIUrl":"10.4070/kcj.2024.0429","url":null,"abstract":"<p><strong>Background and objectives: </strong>We aimed to evaluate the efficacy and safety of coronavirus disease 2019 (COVID-19) vaccination in patients with heart failure (HF) using national databases.</p><p><strong>Methods: </strong>We retrospectively analyzed the data from the Korean nationwide COVID-19 cohort, including patients with HF from February 2021 to June 2022. The study population was divided into the vaccinated (≥2 doses) and unvaccinated (≤1 dose) groups. Clinical outcomes assessed included hospitalization for HF, COVID-19-related events, and cardiovascular complications. Patients were matched by age, sex, and comorbidities, and were followed up for up to 15 months to assess vaccination-associated risks.</p><p><strong>Results: </strong>We included 651,127 patients with HF (mean age 69.5 years; 50.2% male), of whom 112,693 (17.3%) were unvaccinated, and 538,434 (82.7%) were vaccinated. After propensity score matching, 73,559 patients in each group were compared. Over a median follow-up of 6 months, vaccination was associated with a significantly reduced risk of COVID-19 (hazard ratio [HR], 0.27; 95% confidence interval [CI], 0.22-0.33) and critical COVID-19 infection (HR, 0.47; 95% CI, 0.31-0.71). The vaccinated group also had a significantly lower risk of hospitalization for HF (HR, 0.53; 95% CI, 0.52-0.55) and all-cause mortality (HR, 0.18; 95% CI, 0.17-0.18) compared with the unvaccinated group. Additionally, vaccination was associated with a significantly lower risk of stroke, myocardial infarction, myocarditis/pericarditis, and venous thromboembolism compared with the unvaccinated patients (all, p<0.0001).</p><p><strong>Conclusions: </strong>COVID-19 vaccination in patients with HF was associated with a reduced risk of hospitalization for HF, all-cause mortality, and other cardiovascular events.</p>","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":"177-191"},"PeriodicalIF":3.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12929037/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145225520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular Implications in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A State-of-the-Art Review.","authors":"Mithil Gowda Suresh, Safia Mohamed, Harinivaas Shanmugavel Geetha, Sushmita Prabhu, Nitin Trivedi, Priyal Dilip Mehta, Udaya Kumar Damodaran, Ajit Brar, Aalam Sohal, Juniali Hatwal, Akash Batta","doi":"10.4070/kcj.2025.0212","DOIUrl":"10.4070/kcj.2025.0212","url":null,"abstract":"<p><p>Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is the most prevalent chronic liver disease globally and a key driver of cardiometabolic morbidity. Beyond hepatic manifestations, MASLD significantly elevates the risk of cardiovascular disease (CVD)-including myocardial infarction, ischemic stroke, heart failure, and cardiovascular mortality-through overlapping mechanisms such as visceral adiposity, insulin resistance, inflammation, oxidative stress, and dyslipidemia. Epidemiologic data demonstrate a consistent and independent association between MASLD and adverse cardiovascular outcomes. Subclinical changes in vascular structure and function precedes overt events, underscoring the need for early detection and proactive risk stratification. While glucagon-like-peptide 1 receptor agonists and sodium-glucose co-transporter-2 inhibitors offer dual hepatic and cardiovascular benefits, recent trials have revealed nuances in efficacy across patient populations, particularly in heart failure with preserved ejection fraction and cirrhotic cohorts. Non-invasive diagnostics-including elastography, magnetic resonance elastography, magnetic resonance imaging-derived proton density fat fraction, and machine learning-based tools-are enhancing the precision of MASLD staging and risk assessment. However, implementation remains variable, and cost-effectiveness in CVD screening is underexplored. This review synthesizes current knowledge on the MASLD-CVD interface, critically appraises existing evidence, and identifies gaps in mechanistic understanding, diagnostics, and therapeutics. We advocate for an integrated, multidisciplinary framework combining hepatology and cardiology expertise to optimize patient care in this evolving disease landscape.</p>","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":"103-130"},"PeriodicalIF":3.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12929038/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145724254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship Between Food Insecurity and Poor Cardiovascular Health in Korean Adults.","authors":"Danbi Ku, Youn Huh, Wonsock Kim, Jae-Min Park, Jung Yeon Chin, Jung Hwan Kim, Young Sik Kim, Seo Young Kang","doi":"10.4070/kcj.2025.0081","DOIUrl":"10.4070/kcj.2025.0081","url":null,"abstract":"<p><strong>Background and objectives: </strong>The association between food insecurity and cardiovascular health (CVH) in Korean adults remains unclear. This study aimed to investigate the association between food insecurity and CVH in Korean adults.</p><p><strong>Methods: </strong>This study included 14,034 adults aged ≥19 years in the Korea National Health and Nutrition Examination Survey 2019-2021. CVH was defined using the American Heart Association's Life's Simple 7 framework, including smoking status, physical activity, diet, body mass index, total cholesterol, blood pressure, and fasting glucose. Participants were categorized into the food secure or food insecure group based on their survey scores. Multivariate logistic regression analysis was performed to calculate the association between food insecurity and poor CVH.</p><p><strong>Results: </strong>Among the participants, 4.0% belonged to the food insecure group and 96.0% belonged to the food secure group, and 15.3%, 61.4%, and 23.3% of the participants had ideal, intermediate, and poor CVH, respectively. In the multivariate analysis, the odds ratio (95% confidence interval) for poor CVH was 1.32 (1.06-1.64) in food insecure group compared to food secure group. The odds for poor CVH increased as food security status aggravated (p for trend <0.05). Moreover, food insecure group had higher odds of poor status in the following CVH components: smoking and blood pressure.</p><p><strong>Conclusions: </strong>Food insecurity is associated with poor CVH in Korean adults. Specifically, it is associated with current smoking and high blood pressure. Improving food insecurity may help prevent poor CVH in Korea.</p>","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":"144-156"},"PeriodicalIF":3.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12929048/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145225477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}