Korean Circulation Journal最新文献_第4页

Beyond the Left Atrium: Genetic and Renal Determinants of Atrial Fibrillation in Hypertrophic Cardiomyopathy. 左心房以外：肥厚性心肌病心房颤动的遗传和肾脏决定因素。

IF 3.1 3区医学

Korean Circulation Journal Pub Date : 2025-06-26 DOI: 10.4070/kcj.2025.0219

Mi-Hyang Jung

引用次数: 0

Malnutrition in Heart Failure With Preserved Ejection Fraction: Still a Neglected Risk Factor? 有保留射血分数的心力衰竭患者营养不良：仍是一个被忽视的危险因素？

IF 3.1 3区医学

Korean Circulation Journal Pub Date : 2025-06-24 DOI: 10.4070/kcj.2025.0182

Minjae Yoon, Jin Joo Park

引用次数: 0

Optimizing Antiplatelet Therapy in Chronic Kidney Disease: Insights From the TICO Trial in the Context of Contemporary Guidelines. 优化慢性肾脏疾病的抗血小板治疗：当代指南背景下TICO试验的见解

IF 3.1 3区医学

Korean Circulation Journal Pub Date : 2025-06-23 DOI: 10.4070/kcj.2025.0213

Seung-Yul Lee, Jae Youn Moon

引用次数: 0

Clinical Characteristics of Women With Chest Pain: Men From Mars, Women From Venus. 女性胸痛的临床特征：男性来自火星，女性来自金星。

IF 3.1 3区医学

Korean Circulation Journal Pub Date : 2025-06-23 DOI: 10.4070/kcj.2025.0185

Wang-Soo Lee

引用次数: 0

Quantifying Hemodynamic Instability in Fulminant Myocarditis: Clinical Implications for Decision-Making. 量化暴发性心肌炎的血流动力学不稳定性：决策的临床意义。

IF 3.1 3区医学

Korean Circulation Journal Pub Date : 2025-06-23 DOI: 10.4070/kcj.2025.0192

Hyue Mee Kim

引用次数: 0

LV Diastolic Dysfunction and Inappropriate LV Filling Pressure Escalation: The Core of Exercise Intolerance in Heart Failure. 左室舒张功能障碍和不适当的左室充盈压力升高：心力衰竭运动不耐受的核心。

IF 3.1 3区医学

Korean Circulation Journal Pub Date : 2025-06-17 DOI: 10.4070/kcj.2024.0369

Wei-Ming Huang, Chiao-Nan Chen, Hao-Chih Chang, Yen-Tung Liu, Yen-Tze Wu, Tzu-Ying Tseng, Hao-Min Cheng, Wen-Chung Yu, Chern-En Chiang, Chen-Huan Chen, Shih-Hsien Sung

{"title":"LV Diastolic Dysfunction and Inappropriate LV Filling Pressure Escalation: The Core of Exercise Intolerance in Heart Failure.","authors":"Wei-Ming Huang, Chiao-Nan Chen, Hao-Chih Chang, Yen-Tung Liu, Yen-Tze Wu, Tzu-Ying Tseng, Hao-Min Cheng, Wen-Chung Yu, Chern-En Chiang, Chen-Huan Chen, Shih-Hsien Sung","doi":"10.4070/kcj.2024.0369","DOIUrl":"https://doi.org/10.4070/kcj.2024.0369","url":null,"abstract":"Background and objectives: Exercise intolerance is the most common symptom of patients with heart failure (HF), regardless of the phenotypes. We aim to investigate the determinants of exercise capacity in chronic stable HF with reduced, mildly reduced, preserved, and recovered ejection fraction (EF).Methods: Ambulatory HF subjects were recruited for a combined cardiopulmonary exercise test and exercise stress echocardiography. Impaired exercise capacity was referred to a peak oxygen consumption of <14 mL/kg/min, and a relationship between minute ventilation and carbon dioxide production of >34 was defined as ventilatory inefficiency.Results: Among 66 participants, there were 16 HF with reduced EF, 18 HF with mildly reduced EF, 12 HF preserved EF, and 20 HF recovered EF. Diastolic dysfunction indices were independently predictive of impaired exercise capacity (odds ratio [OR], 3.847; 95% confidence interval [CI], 1.369-10.810). Global longitudinal strain (GLS) at rest was independently correlated with ventilatory inefficiency (OR, 1.404; 95% CI, 1.050-1.877). Among the exercise indices, the peak medial E/e' to cardiac output (CO) ratio was independently associated with impaired exercise capacity (OR, 3.478; 95% CI, 1.313-9.214) and peak GLS was best related to ventilatory inefficiency (OR, 1.403; 95% CI, 1.076-1.828).Conclusions: Among resting and exertional echocardiographic variables, the peak medial E/e' to CO ratio, a non-invasive assessment of exertional left ventricular filling pressure indexed to CO, was the major determinant of exercise capacity in patients with different HF phenotypes.","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144742382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Age-Dependent Role of Genetics and Renal Function for Atrial Fibrillation Development in Hypertrophic Cardiomyopathy. 肥厚性心肌病患者房颤发展中遗传和肾功能的年龄依赖性作用。

IF 3.1 3区医学

Korean Circulation Journal Pub Date : 2025-06-16 DOI: 10.4070/kcj.2025.0048

Hyemoon Chung, Yoonjung Kim, Jiwon Seo, In-Soo Kim, Sungsoo Cho, Chul-Hwan Park, Tae Hoon Kim, Se-Joong Rim, Kyung-A Lee, Eui-Young Choi

{"title":"Age-Dependent Role of Genetics and Renal Function for Atrial Fibrillation Development in Hypertrophic Cardiomyopathy.","authors":"Hyemoon Chung, Yoonjung Kim, Jiwon Seo, In-Soo Kim, Sungsoo Cho, Chul-Hwan Park, Tae Hoon Kim, Se-Joong Rim, Kyung-A Lee, Eui-Young Choi","doi":"10.4070/kcj.2025.0048","DOIUrl":"https://doi.org/10.4070/kcj.2025.0048","url":null,"abstract":"Background and objectives: The objective of this study was to investigate whether genetic, structural, and clinical factors were associated with atrial fibrillation (AF) in patients with hypertrophic cardiomyopathy (HCM).Methods: Of the 212 prospectively enrolled patients in the HCM genetic registry, 33 had initial AF, and the remaining 179 (126 males, 58±13 years) were followed up for the development of new-onset AF.Results: Patients with initial AF had older age, lower estimated glomerular filtration rate (eGFR), lower left ventricular (LV) global longitudinal strain, higher left atrial volume index (LAVI), and higher LV extracellular volume fraction. During a median follow-up period of 916 (400-1,327) days, AF occurred in 12 (6.7%) patients. In Cox regression analysis, lower eGFR (hazard ratio per 1 mL/min/1.73 m² increase, 0.93; p=0.007), LV ejection fraction (hazard ratio, 0.82; p=0.009), and higher LAVI (hazard ratio, 1.07; p=0.010) were associated with increased risk of future AF. The addition of eGFR to LAVI significantly increased the global χ² value (8.508 to 15.017; p=0.006). Among patients younger than 65 years (n=128), those with any sarcomere variants (pathogenic and variants of uncertain significance [VUS], n=77) had a higher prevalence of overall AF (initial and new-onset, 82.4% vs. 56.8%; p=0.045).Conclusions: In patients with HCM, decreased renal function provides an additive predictive value on LAVI for future AF. In patients younger than 65, the presence of sarcomere variants, including VUS, is related to a higher prevalence of AF.","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144742409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pregnancy in Women With Fontan Circulation: Strategic Management for a High-Risk. Fontan循环妇女妊娠：高危策略管理。

IF 3 3区医学

Korean Circulation Journal Pub Date : 2025-06-04 DOI: 10.4070/kcj.2025.0176

Soo-Jin Kim

引用次数: 0

When Compatibility Creates Inequality: Blood Type O and the Korean Heart Transplant System. 当相容性造成不平等：O型血和韩国心脏移植系统。

IF 3 3区医学

Korean Circulation Journal Pub Date : 2025-06-01 DOI: 10.4070/kcj.2025.0125

Soo Yong Lee

引用次数: 0

Osfit™, a Novel Stent Designed for the Treatment of Coronary Ostial Lesions: Initial Clinical Experience and Intravascular Ultrasound Evaluation. 用于治疗冠状动脉口病变的新型支架Osfit™：初步临床经验和血管内超声评估

IF 3 3区医学

Korean Circulation Journal Pub Date : 2025-06-01 Epub Date: 2025-02-03 DOI: 10.4070/kcj.2024.0256

Kyoung-Woo Seo, Seung-Jea Tahk, Hyoung-Mo Yang, Hong-Seok Lim, Myeong-Ho Yoon, So-Yeon Choi

{"title":"Osfit™, a Novel Stent Designed for the Treatment of Coronary Ostial Lesions: Initial Clinical Experience and Intravascular Ultrasound Evaluation.","authors":"Kyoung-Woo Seo, Seung-Jea Tahk, Hyoung-Mo Yang, Hong-Seok Lim, Myeong-Ho Yoon, So-Yeon Choi","doi":"10.4070/kcj.2024.0256","DOIUrl":"10.4070/kcj.2024.0256","url":null,"abstract":"Background and objectives: Stent implantation for coronary ostial lesions is challenging. This study evaluated the feasibility, safety, and immediate procedural results of the Osfit™, innovatively designed sirolimus drug-eluting stent delivery system for the treatment of coronary ostial lesions.Methods: The Osfit™ has a 5 mm long extended balloon proximal to the stent (bare balloon without mounted stent). When inflated at 1.5 atm, only bare balloon inflated and acts like a stopper. We evaluated the technical feasibility in 49 patients with a coronary ostial lesion (defined as stenosis within 3 mm from the origin of the vessel) who had received the Osfit™. Intravascular ultrasound (IVUS) analysis was done in 11 patients who consented to IVUS examination, and the depth from the proximal edge of the stent to the ostial plane (DSO) was measured.Results: In all 49 lesions, stents were successfully implanted in one single angiographic view without obvious stent protrusion or definite angiographic missing of the ostium. The proportions of aorto-ostial, and bifurcation lesions were 28.6% and 71.4%, respectively. The DSO was 0.2±0.69 mm, and the proximal stent edges were located within 1 mm of the ostial edge in all patients. No adverse events like death, myocardial infarction, target lesion revascularization, target vessel revascularization or stent thrombosis were reported during the in-hospital period or within 30 days.Conclusions: The implantation of the Osfit™ for coronary ostial lesions appears to be an accurate and safe procedure that may reduce multiple angiographic projections and advanced skills.","PeriodicalId":17850,"journal":{"name":"Korean Circulation Journal","volume":" ","pages":"497-508"},"PeriodicalIF":3.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12206610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0