Journal of The Royal Society Interface最新文献_第9页

Quantification of Trypanosoma brucei social motility indicates different colony growth phases. 布鲁氏锥虫的社会运动量化表明不同的菌落生长阶段。

IF 3.7 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2024-12-01 Epub Date: 2024-12-18 DOI: 10.1098/rsif.2024.0469

Andreas Kuhn, Timothy Krüger, Magdalena Schüttler, Markus Engstler, Sabine C Fischer

{"title":"Quantification of Trypanosoma brucei social motility indicates different colony growth phases.","authors":"Andreas Kuhn, Timothy Krüger, Magdalena Schüttler, Markus Engstler, Sabine C Fischer","doi":"10.1098/rsif.2024.0469","DOIUrl":"10.1098/rsif.2024.0469","url":null,"abstract":"In vitro colonies of the flagellated parasite Trypanosoma brucei exhibit characteristic fingering instability patterns. To enable data-driven and data-validated mechanistic modelling of these complex growth processes, it is crucial to first establish appropriate quantitative metrics beyond qualitative image comparisons. We present a quantification approach based on two scale-free metrics designed to characterize the shape of two-dimensional colonies. Originally developed for yeast colonies, we adapted, modified and extended this analysis pipeline for the Trypanosoma system. By combining these quantitative measurements with colony growth simulations based on the Eden model, we identified two distinct growth phases in social motility-exhibiting colonies: an initial phase of mainly circular expansion, followed by a transition to an almost exclusive finger-growing phase. These phases remain robust with increasing cell numbers and upon partial inhibition of finger formation. A newly developed anisotropy index reveals that partial inhibition leads to increased colony anisotropy over time. Our results provide objective measurements that advance the understanding of social motility and serve as a foundation for future mechanistic modelling efforts. Furthermore, our approach offers a blueprint for investigations of other colony-forming microorganisms, such as yeast or bacteria, emphasizing the broader applicability of developing appropriate metrics for complex biological phenomena.","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 221","pages":"20240469"},"PeriodicalIF":3.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11653114/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Model-informed optimal allocation of limited resources to mitigate infectious disease outbreaks in societies at war. 根据模型优化有限资源的分配，以缓解战争社会中传染病的爆发。

IF 3.7 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2024-11-01 Epub Date: 2024-11-06 DOI: 10.1098/rsif.2024.0575

Vaibhava Srivastava, Drik Sarkar, Claus Kadelka

{"title":"Model-informed optimal allocation of limited resources to mitigate infectious disease outbreaks in societies at war.","authors":"Vaibhava Srivastava, Drik Sarkar, Claus Kadelka","doi":"10.1098/rsif.2024.0575","DOIUrl":"10.1098/rsif.2024.0575","url":null,"abstract":"Infectious diseases thrive in war-torn societies. The recent sharp increase in human conflict and war thus requires the development of disease mitigation tools that account for the specifics of war, such as the scarcity of important public health resources. We developed a compartmental, differential equation-based disease model that considers key social, war and disease mechanisms, such as gender homophily and the replacement of soldiers. This model enables the identification of optimal allocation strategies that, given limited resources required for treating infected individuals, minimize disease burden, assessed by total mortality and final epidemic size. A comprehensive model analysis reveals that the level of resource scarcity fundamentally affects the optimal allocation. Desynchronization of the epidemic peaks among several population subgroups emerges as a desirable principle since it reduces disease spread between different subgroups. Further, the level of preferential mixing among people of the same gender, gender homophily, proves to strongly affect disease dynamics and optimal treatment allocation strategies, highlighting the importance of accurately accounting for heterogeneous mixing patterns. Altogether, the findings help answer a timely question: how can infectious diseases be best controlled in societies at war? The developed model can be easily extended to specific diseases, countries and interventions.","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 220","pages":"20240575"},"PeriodicalIF":3.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11538904/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Upper bill bending as an adaptation for nectar feeding in hummingbirds. 上喙弯曲是蜂鸟取食花蜜的一种适应。

IF 3.7 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2024-11-01 Epub Date: 2024-11-27 DOI: 10.1098/rsif.2024.0286

Alejandro Rico-Guevara, Diego Sustaita, Kristiina J Hurme, Jenny E Hanna, Sunghwan Jung, Daniel J Field

{"title":"Upper bill bending as an adaptation for nectar feeding in hummingbirds.","authors":"Alejandro Rico-Guevara, Diego Sustaita, Kristiina J Hurme, Jenny E Hanna, Sunghwan Jung, Daniel J Field","doi":"10.1098/rsif.2024.0286","DOIUrl":"10.1098/rsif.2024.0286","url":null,"abstract":"Observations of maxillary (upper bill) bending in hummingbirds have been considered an optical illusion, yet a recent description of out-of-phase opening and closing between their bill base and tip suggests a genuine capacity for bill bending. We investigate bill kinematics during nectar feeding in six species of hummingbirds. We employed geometric morphometrics to identify bending zones and combined these data with measurements of bill flexural rigidity from micro-computed tomography scans to better understand the flexing mechanism. We found that the mandible remains in place throughout the licking cycle, while the maxilla undergoes significant shape deformation, such that the distal portion of the upper bill bends upwards. We propose that bill bending is a key component of the drinking mechanism in hummingbirds, allowing the coordination of bill function (distal wringing and basal expansion) and tongue function (raking/squeegeeing) during intra-oral transport. We present a fluid analysis that reveals a combination of pressure-driven (Poiseuille) and boundary-driven (Couette) flows, which have previously been thought to represent alternative drinking mechanisms. Bill bending allows for separation of the bill tips while maintaining a tightly closed middle section of the bill, enabling nectar exploitation in long and narrow flowers that can exclude less efficient pollinators.","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 220","pages":"20240286"},"PeriodicalIF":3.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11601124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142729691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The suppression of ocean waves by biogenic slicks. 生物浮渣对海浪的压制。

IF 3.7 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2024-11-01 Epub Date: 2024-11-13 DOI: 10.1098/rsif.2024.0385

Nathan J M Laxague, Christopher J Zappa, Shantanu Soumya, Oliver Wurl

{"title":"The suppression of ocean waves by biogenic slicks.","authors":"Nathan J M Laxague, Christopher J Zappa, Shantanu Soumya, Oliver Wurl","doi":"10.1098/rsif.2024.0385","DOIUrl":"10.1098/rsif.2024.0385","url":null,"abstract":"Ocean waves are significantly damped by biogenic surfactants, which accumulate at the sea surface in every ocean basin. The growth, development, and breaking of short wind-driven surface waves are key mediators of the air-sea exchange of momentum, heat and trace gases. The mechanisms through which surfactants suppress waves have been studied in great detail through careful laboratory experimentation in quasi-one-dimensional wave tanks. However, the spatial scales over which this damping occurs in structurally complex surfactant slicks on the real ocean have not been resolved. Here, we present the results of field observations of the spatial response of decimetre- to millimetre-scale waves to biogenic surfactant slicks. We found that wave damping in organic material-rich coastal waters resulted in a net (spatio-temporally averaged) reduction of approximately 50% in wave slope variance relative to the open ocean for low to moderate wind speeds. This reduction of wave slope variance is understood to result in a corresponding reduction in momentum input to the wave field. This significant effect had thus far evaded quantification due in large part to the enormous range of scales required for its description-spanning the sea surface microlayer to the ocean submesoscale.","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 220","pages":"20240385"},"PeriodicalIF":3.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557231/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142621268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evolutionary mechanisms that promote cooperation may not promote social welfare. 促进合作的进化机制未必能促进社会福利。

IF 3.7 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2024-11-01 Epub Date: 2024-11-27 DOI: 10.1098/rsif.2024.0547

The Anh Han, Manh Hong Duong, Matjaz Perc

{"title":"Evolutionary mechanisms that promote cooperation may not promote social welfare.","authors":"The Anh Han, Manh Hong Duong, Matjaz Perc","doi":"10.1098/rsif.2024.0547","DOIUrl":"10.1098/rsif.2024.0547","url":null,"abstract":"Understanding the emergence of prosocial behaviours among self-interested individuals is an important problem in many scientific disciplines. Various mechanisms have been proposed to explain the evolution of such behaviours, primarily seeking the conditions under which a given mechanism can induce highest levels of cooperation. As these mechanisms usually involve costs that alter individual pay-offs, it is, however, possible that aiming for highest levels of cooperation might be detrimental for social welfare-the latter broadly defined as the total population pay-off, taking into account all costs involved for inducing increased prosocial behaviours. Herein, by comparing stochastic evolutionary models of two well-established mechanisms of prosocial behaviour-namely, peer and institutional incentives-we demonstrate that the objectives of maximizing cooperation and of maximizing social welfare are often misaligned. First, while peer punishment is often more effective than peer reward in promoting cooperation-especially with a higher impact-to-cost ratio-the opposite is true for social welfare. In fact, welfare typically decreases (increases) with this ratio for punishment (reward). Second, for institutional incentives, while maintaining similar levels of cooperation, rewards result in positive social welfare across a much broader range of parameters. Furthermore, both types of incentives often achieve optimal social welfare when their impact is moderate rather than maximal, indicating that careful planning is essential for costly institutional mechanisms to optimize social outcomes. These findings are consistent across varying mutation rates, selection intensities and game configurations. Overall, we argue for the need of adopting social welfare as the main optimization objective when designing and implementing evolutionary mechanisms for social and collective goods.","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 220","pages":"20240547"},"PeriodicalIF":3.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11597467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142729637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Global and local identifiability analysis of a nonlinear biphasic constitutive model in confined compression. 约束压缩非线性双相构造模型的全局和局部可识别性分析

IF 3.7 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2024-11-01 Epub Date: 2024-11-13 DOI: 10.1098/rsif.2024.0415

John M Peloquin, Dawn M Elliott

{"title":"Global and local identifiability analysis of a nonlinear biphasic constitutive model in confined compression.","authors":"John M Peloquin, Dawn M Elliott","doi":"10.1098/rsif.2024.0415","DOIUrl":"10.1098/rsif.2024.0415","url":null,"abstract":"Application of biomechanical models relies on model parameters estimated from experimental data. Parameter non-identifiability, when the same model output can be produced by many sets of parameter values, introduces severe errors yet has received relatively little attention in biomechanics and is subtle enough to remain unnoticed in the absence of deliberate verification. The present work develops a global identifiability analysis method in which cluster analysis and singular value decomposition are applied to vectors of parameter-output variable correlation coefficients. This method provides a visual representation of which specific experimental design elements are beneficial or harmful in terms of parameter identifiability, supporting the correction of deficiencies in the test protocol prior to testing physical specimens. The method was applied to a representative nonlinear biphasic model for cartilaginous tissue, demonstrating that confined compression data does not provide identifiability for the biphasic model parameters. This result was confirmed by two independent analyses: local analysis of the Hessian of a sum-of-squares error cost function and observation of the behaviour of two optimization algorithms. Therefore, confined compression data are insufficient for the calibration of general-purpose biphasic models. Identifiability analysis by these or other methods is strongly recommended when planning future experiments.","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 220","pages":"20240415"},"PeriodicalIF":3.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142623197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physical mechanism reveals bacterial slowdown above a critical number of flagella. 物理机制揭示了细菌在鞭毛数量超过临界值时速度减慢的现象。

IF 3.7 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2024-11-01 Epub Date: 2024-11-06 DOI: 10.1098/rsif.2024.0283

Maria Tătulea-Codrean, Eric Lauga

{"title":"Physical mechanism reveals bacterial slowdown above a critical number of flagella.","authors":"Maria Tătulea-Codrean, Eric Lauga","doi":"10.1098/rsif.2024.0283","DOIUrl":"10.1098/rsif.2024.0283","url":null,"abstract":"Numerous studies have explored the link between bacterial swimming and the number of flagella, a distinguishing feature of motile multi-flagellated bacteria. We revisit this open question using augmented slender-body theory simulations, in which we resolve the full hydrodynamic interactions within a bundle of helical filaments rotating and translating in synchrony. Unlike previous studies, our model considers the full torque-speed relationship of the bacterial flagellar motor, revealing its significant impact on multi-flagellated swimming. Because the viscous load per motor decreases with the flagellar number, the bacterial flagellar motor transitions from the high-load to the low-load regime at a critical number of filaments, leading to bacterial slowdown as further flagella are added to the bundle. We explain the physical mechanism behind the observed slowdown as an interplay between the load-dependent generation of torque by the motor, and the load-reducing cooperativity between flagella, which consists of both hydrodynamic and non-hydrodynamic components. The theoretically predicted critical number of flagella is remarkably close to the values reported for the model organism Escherichia coli. Our model further predicts that the critical number of flagella increases with viscosity, suggesting that bacteria can enhance their swimming capacity by growing more flagella in more viscous environments, consistent with empirical observations.","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 220","pages":"20240283"},"PeriodicalIF":3.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seeing the piles of the velvet bending under our finger sliding over a tactile stimulator improves the feeling of the fabric. 手指在触觉刺激器上滑动时，看到成堆的天鹅绒在我们的手指下弯曲，从而改善了织物的触感。

IF 3.7 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2024-11-01 Epub Date: 2024-11-06 DOI: 10.1098/rsif.2024.0368

Laurence Mouchnino, Brigitte Camillieri, Jenny Faucheu, Mihaela Juganaru, Alix Moinon, Jean Blouin, Marie-Ange Bueno

{"title":"Seeing the piles of the velvet bending under our finger sliding over a tactile stimulator improves the feeling of the fabric.","authors":"Laurence Mouchnino, Brigitte Camillieri, Jenny Faucheu, Mihaela Juganaru, Alix Moinon, Jean Blouin, Marie-Ange Bueno","doi":"10.1098/rsif.2024.0368","DOIUrl":"10.1098/rsif.2024.0368","url":null,"abstract":"Using friction modulation to simulate fabrics with a tactile stimulator (i.e. virtual surface) is not sufficient to render fabric touch and even more so for hairy fabrics. We hypothesized that seeing the pile of the velvet darken or lighten depending on changes in the finger movement direction on the virtual surface should improve the velvet fabric rendering. Participants actively rubbed a tactile device or a velvet fabric looking at a screen that showed a synthesized image of a velvet that either remained static (V-static) or darkening/lightening with the direction of touch (V-moving). We showed that in V-moving condition, the touched surface was always perceived rougher, which is a descriptor of a real velvet (Experiment 1). Using electroencephalography and sources localization analyses, we found increased activity in the occipital and inferior parietal lobes (Experiment 2) when seeing dark and shining traces during back-and-forth finger movements over the virtual surface. This suggests that these two posterior cortical regions work together to evaluate visuo-tactile congruence between the seen and the felt (tactile). The visuo-tactile binding, evidenced by neural synchronization (specifically, theta band (5-7 Hz) oscillation) in the left inferior posterior parietal lobule, is consistent with enhanced integration of information and probably contributed to the emergence of a more realistic velvet representation.","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 220","pages":"20240368"},"PeriodicalIF":3.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11538944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reply to 'Experimental measurement of assembly indices are required to determine the threshold for life'. 对 "确定生命阈值需要对装配指数进行实验测量 "的答复

IF 3.7 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2024-11-01 Epub Date: 2024-11-20 DOI: 10.1098/rsif.2024.0622

Robert M Hazen, Peter C Burns, H James Cleaves Ii, Robert T Downs, Sergey V Krivovichev, Michael L Wong

引用次数: 0

Cocoon microstructures through the lens of topological persistence. 通过拓扑持久性透视茧微结构

IF 3.7 2区综合性期刊

Journal of The Royal Society Interface Pub Date : 2024-11-01 Epub Date: 2024-11-13 DOI: 10.1098/rsif.2024.0218

Vira Raichenko, Nikolai Rosenthal, Michaela Eder, Myfanwy E Evans

引用次数: 0