Journal of The Royal Society Interface最新文献

{"title":"Frequency-dependent returns in nonlinear public goods games.","authors":"Christoph Hauert, Alex McAvoy","doi":"10.1098/rsif.2024.0334","DOIUrl":"10.1098/rsif.2024.0334","url":null,"abstract":"<p><p>When individuals interact in groups, the evolution of cooperation is traditionally modelled using the framework of public goods games. These models often assume that the return of the public goods depends linearly on the fraction of contributors. In contrast, in real-life public goods interactions, the return can depend on the size of the investor pool as well. Here, we consider a model in which the multiplication factor (marginal per capita return) for the public goods depends linearly on how many contribute, which results in a nonlinear model of public goods. This simple model breaks the curse of dominant defection found in linear public goods interactions and gives rise to richer dynamical outcomes in evolutionary settings. We provide an in-depth analysis of the more varied decisions by the classical rational player in nonlinear public goods interactions as well as a mechanistic, microscopic derivation of the evolutionary outcomes for the stochastic dynamics in finite populations and in the deterministic limit of infinite populations. This kind of nonlinearity provides a natural way to model public goods with diminishing returns as well as economies of scale.</p>","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 219","pages":"20240334"},"PeriodicalIF":3.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11521596/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142546202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inertial coupling of the hummingbird body in the flight mechanics of an escape manoeuvre.","authors":"Mohammad Nasirul Haque, Bret W Tobalske, Bo Cheng, Haoxiang Luo","doi":"10.1098/rsif.2024.0391","DOIUrl":"10.1098/rsif.2024.0391","url":null,"abstract":"<p><p>When a hovering hummingbird performs a rapid escape manoeuvre in response to a perceived threat from the front side, its body may go through simultaneous pitch, yaw and roll rotations. In this study, we examined the inertial coupling of the three-axis body rotations and its effect on the flight mechanics of the manoeuvre using analyses of high-speed videos as well as high-fidelity computational modelling of the aerodynamics and inertial forces. We found that while a bird's pitch-up was occurring, inertial coupling between yaw and roll helped slow down and terminate the pitch, thus serving as a passive control mechanism for the manoeuvre. Furthermore, an inertial coupling between pitch-up and roll can help accelerate yaw before the roll-yaw coupling. Different from the aerodynamic mechanisms that aircraft and animal flyers typically rely on for flight control, we hypothesize that inertial coupling is a built-in mechanism in the flight mechanics of hummingbirds that helps them achieve superb aerial agility.</p>","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 219","pages":"20240391"},"PeriodicalIF":3.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11684407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142546203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spatial correlations in laboratory insect swarms.","authors":"Andy M Reynolds","doi":"10.1098/rsif.2024.0450","DOIUrl":"10.1098/rsif.2024.0450","url":null,"abstract":"<p><p>In contrast with flocks of birds, schools of fish and herds of animals, swarms of the non-biting midge <i>Chironomus riparius</i> do not possess global order and under quiescent conditions velocities are only weakly correlated at long distances. Without such order it is challenging to characterize the collective behaviours of the swarms which until now have only been evident in their coordinated responses to disturbances. Here I show that the positions of the midges in laboratory swarms are maximally anticorrelated. This novel form of long-range ordering has until now gone unnoticed in the literature on collective animal movements. Here, its occurrence is attributed to midges being, in nearly equal measure, attracted towards the centre of the swarm and repelled by one another. It is shown that the midge swarms are poised at the cusp of a stable-unstable phase transition.</p>","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 219","pages":"20240450"},"PeriodicalIF":3.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modelling the mechanisms of antibody mixtures in viral infections: the cases of sequential homologous and heterologous dengue infections.","authors":"Charlotte Dugourd-Camus, Claudia P Ferreira, Mostafa Adimy","doi":"10.1098/rsif.2024.0182","DOIUrl":"10.1098/rsif.2024.0182","url":null,"abstract":"<p><p>Antibodies play an essential role in the immune response to viral infections, vaccination or antibody therapy. Nevertheless, they can be either protective or harmful during the immune response. Moreover, competition or cooperation between mixed antibodies can enhance or reduce this protective or harmful effect. Using the laws of chemical reactions, we propose a new approach to modelling the antigen-antibody complex activity. The resulting expression covers not only purely competitive or purely independent binding but also synergistic binding which, depending on the antibodies, can promote either neutralization or enhancement of viral activity. We then integrate this expression of viral activity in a within-host model and investigate the existence of steady-states and their asymptotic stability. We complete our study with numerical simulations to illustrate different scenarios: firstly, where both antibodies are neutralizing and secondly, where one antibody is neutralizing and the other enhancing. The results indicate that efficient viral neutralization is associated with purely independent antibody binding, whereas strong viral activity enhancement is expected in the case of purely competitive antibody binding. Finally, data collected during a secondary dengue infection were used to validate the model. The dataset includes sequential measurements of virus and antibody titres during viremia in patients. Data fitting shows that the two antibodies are in strong competition, as the synergistic binding is low. This contributes to the high levels of virus titres and may explain the antibody-dependent enhancement phenomenon. Besides, the mortality of infected cells is almost twice as high as that of susceptible cells, and the heterogeneity of viral kinetics in patients is associated with variability in antibody responses between individuals. Other applications of the model may be considered, such as the efficacy of vaccines and antibody-based therapies.</p>","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 219","pages":"20240182"},"PeriodicalIF":3.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11523103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term tracing of individual human neural cells using multiphoton microscopy and photoconvertible polymer capsules.","authors":"Ivan V Smirnov, Veronika S Usatova, Mikhail A Berestovoy, Andrei B Fedotov, Aleksandr A Lanin, Vsevolod V Belousov, Gleb B Sukhorukov","doi":"10.1098/rsif.2024.0497","DOIUrl":"10.1098/rsif.2024.0497","url":null,"abstract":"<p><p>The study of human neural cells, their behaviour and migration are important areas of research in the biomedical field, particularly for potential therapeutic applications. The safety of using neural cells in therapy is still a concern due to a lack of information on long-term changes that may occur. While current methods of cell tracing explore gene manipulations, we elaborate approaches to cell marking with no genetic interference. In this study, we present a novel method for labelling and tracking neural cells using cell-impregnatable photoconvertible polyelectrolyte microcapsules. These capsules demonstrated low cytotoxicity with no effect on the differentiation ability of the neural cells, maintained a high level of fluorescent signal and ability for tracing individual neural cells for over 7 days. The capsules modified with rhodamine- and fluorescein-based dyes were demonstrated to undergo photoconversion by both one- and two-photon lasers while being internalized by neural cells. The finding gives the possibility to select individual capsules inside multicellular structures like spheroids and tissues and alternate their fluorescent appearance. Thus, we can track individual cell paths in complex systems. This new method offers a promising alternative for studying neural cells' long-term behaviour and migration in complex systems such as three-dimensional cellular populations.</p>","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 219","pages":"20240497"},"PeriodicalIF":3.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11521627/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142546204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A computational approach to selective attention in embodied approaches to cognitive archaeology.","authors":"Axel Constant, Laura Desirèe Di Paolo, Avel Guénin-Carlut, Luis M Martinez, Felipe Criado-Boado, Johannes Müeller, Andy Clark","doi":"10.1098/rsif.2024.0508","DOIUrl":"10.1098/rsif.2024.0508","url":null,"abstract":"<p><p>This article proposes a novel computational approach to embodied approaches in cognitive archaeology called computational cognitive archaeology (CCA). We argue that cognitive archaeology, understood as the study of the human mind based on archaeological findings such as artefacts and material remains excavated and interpreted in the present, can benefit from the integration of novel methods in computational neuroscience interested in modelling the way the brain, the body and the environment are coupled and parameterized to allow for adaptive behaviour. We discuss the kind of tasks that CCA may engage in with a narrative example of how one can model the cumulative cultural evolution of the material and cognitive components of technologies, focusing on the case of knapping technology. This article thus provides a novel theoretical framework to formalize research in cognitive archaeology using recent developments in computational neuroscience.</p>","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 219","pages":"20240508"},"PeriodicalIF":3.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11461058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subtle frequency matching reveals resonant phenomenon in the flight of Odonata.","authors":"C Aracheloff, R Garrouste, A Nel, R Godoy-Diana, B Thiria","doi":"10.1098/rsif.2024.0401","DOIUrl":"https://doi.org/10.1098/rsif.2024.0401","url":null,"abstract":"<p><p>In this work, we investigate the connection between the flight flapping frequency and the intrinsic wing properties in Odonata (dragonflies and damselflies). For such large flying insect species, it has been noted that the wingbeat frequency is significantly lower than the structural resonance of the wing itself. However, the structural resonance mechanism is often evoked in the literature for flying and swimming animals as a means to increase locomotion performance. Here, we show that the flight of Odonata is based on a nonlinear mechanism that strongly depends on the wingbeat amplitude. For large flapping amplitudes (as observed in natural flight), the resonant frequency of the wings decreases with respect to its value at low amplitudes to eventually match the wingbeat frequency used in flight. By means of this nonlinear resonance, Odonata keep a strong wing stiffness while benefiting from a passive energy-saving mechanism based on the dynamic softening of the wing.</p>","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 219","pages":"20240401"},"PeriodicalIF":3.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11496952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142502958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geometric constraint of mechanosensing by modification of hydrogel thickness prevents stiffness-induced differentiation in bone marrow stromal cells.","authors":"Maria L Hernandez-Miranda, Dichu Xu, Aya A Ben Issa, David A Johnston, Martin Browne, Richard B Cook, Bram G Sengers, Nicholas D Evans","doi":"10.1098/rsif.2024.0485","DOIUrl":"10.1098/rsif.2024.0485","url":null,"abstract":"<p><p>Extracellular matrix (ECM) stiffness is fundamental in cell division, movement and differentiation. The stiffness that cells sense is determined not only by the elastic modulus of the ECM material but also by ECM geometry and cell density. We hypothesized that these factors would influence cell traction-induced matrix deformations and cellular differentiation in bone marrow stromal cells (BMSCs). To achieve this, we cultivated BMSCs on polyacrylamide hydrogels that varied in elastic modulus and geometry and measured cell spreading, cell-imparted matrix deformations and differentiation. At low cell density BMSCs spread to a greater extent on stiff compared with soft hydrogels, or on thin compared with thick hydrogels. Cell-imparted matrix deformations were greater on soft compared with stiff hydrogels or thick compared with thin hydrogels. There were no significant differences in osteogenic differentiation relative to hydrogel elastic modulus and thickness. However, increased cell density and/or prolonged culture significantly reduced matrix deformations on soft hydrogels to levels similar to those on stiff substrates. This suggests that at high cell densities cell traction-induced matrix displacements are reduced by both neighbouring cells and the constraint imposed by an underlying stiff support. This may explain observations of the lack of difference in osteogenic differentiation as a function of stiffness.</p>","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 219","pages":"20240485"},"PeriodicalIF":3.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11444768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Why the Fermi paradox may not be well explained by Wong and Bartlett's theory of civilization collapse. A Comment on: 'Asymptotic burnout and homeostatic awakening: a possible solution to the Fermi paradox?' (2022) by Wong and Bartlett.","authors":"Chris J Jackson, Christian Criado-Perez","doi":"10.1098/rsif.2024.0140","DOIUrl":"10.1098/rsif.2024.0140","url":null,"abstract":"<p><p>Wong and Bartlett explain the Fermi paradox by arguing that neither human nor extra-terrestrial civilizations can escape the time window singularity which, they claim, results from the way in which social characteristics of civilizations follow super-linear growth curves of cities. We question if data at the city level necessarily can lead to conclusions at the civilization level. More specifically, we suggest ways in which learnings from research, foresight, diversity and effective future government might act outside of their model to regulate super-linear growth curves of civilizations, and thus substantively increase the likelihood of civilizations progressing towards higher levels of the Kardashev scale. Moreover, we believe their claimed history of the collapse of terrestrial societies used to evidence their model is difficult to justify. Overall, we cast reasonable doubt on the ability of their proposed model to satisfactorily explain the Fermi paradox.</p>","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 219","pages":"20240140"},"PeriodicalIF":3.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11523100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142502960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New lessons from biology for economics and business: a systems approach to non-market environments.","authors":"YunHee Lee, Colin Mayer, Dennis Snower, Denis Noble","doi":"10.1098/rsif.2024.0457","DOIUrl":"10.1098/rsif.2024.0457","url":null,"abstract":"<p><p>Drawing on recent advances in biology, this paper describes a systems approach, 'Systems Public Affairs' (SPA), to integrate non-market strategies in corporate purposes and strategies. Just as the environment of organisms affects and is affected by their development and evolution, so individuals and businesses adjust to and can shape their non-market environment, which we define as 'a historically formed national and social sphere, including laws, regulations, and policies, which supports, maintains and restrains the operation and preservation of markets'. The paper uses cases from South Korea to illustrate this approach. Emergent ideas in biology have great relevance for micro-foundations of business. Traditionally, economic activities are outcomes of individualistic decision-makers, each promoting their distinct objectives within economic markets. In the SPA approach, decision makers in the domains of business, policy and civil society collaborate in shaping non-market environments to align business objectives with public interest. This requires agency to rise to higher levels than that of businesses, policymakers and civil society through collaboration and experimentation in the presence of stochasticity and radical uncertainty. Analogous to the advancement of organism evolution through emergence of nervous systems and learning, so alignment of organizations with their non-market environments accelerates economic and social development.</p>","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"21 219","pages":"20240457"},"PeriodicalIF":3.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11521624/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142546205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}