Qiming Wu, Zhuyan Xu, Xiaomin Ma, Juan Li, Jun Du, Jing Ji, Xiaomeng Ling, Juntao Kan, Min Zhao
{"title":"Association of low muscle mass index and sarcopenic obesity with knee osteoarthritis: a systematic review and meta-analysis.","authors":"Qiming Wu, Zhuyan Xu, Xiaomin Ma, Juan Li, Jun Du, Jing Ji, Xiaomeng Ling, Juntao Kan, Min Zhao","doi":"10.1080/15502783.2024.2352393","DOIUrl":"10.1080/15502783.2024.2352393","url":null,"abstract":"<p><strong>Background: </strong>Sarcopenia and knee osteoarthritis are common age-related diseases that have become important public health issues worldwide. Few studies have reported the association between muscle mass loss and knee osteoarthritis. This may be due to the high level of heterogeneity between studies stemming from different definitions of muscle mass loss.</p><p><strong>Methods: </strong>The systematic searches were carried out in PubMed and Web of Science from the inception of the databases until 13 January 2023, by two independent researchers. Pooled odds ratios (ORs) for overall and subgroup analyses were obtained using either a random effects model (I<sup>2</sup> >50%) or fixed effects model (I<sup>2</sup> ≤50%) in Stata.</p><p><strong>Results: </strong>Of the 1,606 studies identified, we ultimately included 12 articles on the association between muscle mass and knee osteoarthritis (prospective: <i>n</i> = 5; cross-sectional: <i>n</i> = 7). Low-quality evidence indicated that low muscle mass index and sarcopenic obesity increase the odds of knee osteoarthritis (low muscle mass index OR: 1.36, 95% CI: 1.13-1.64; sarcopenic obesity OR: 1.78, 95% CI: 1.35-2.34). However, no association was observed between general sarcopenia or low muscle mass with knee osteoarthritis.</p><p><strong>Conclusion: </strong>This systematic review and meta-analysis revealed that low muscle mass index and sarcopenic obesity were associated with an increased risk of developing knee osteoarthritis.</p>","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"21 1","pages":"2352393"},"PeriodicalIF":5.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11123550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141076153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acute ingestion of caffeinated chewing gum reduces fatigue index and improves 400-meter performance in trained sprinters: a double-blind crossover trial.","authors":"Yi-Jie Shiu, Che-Hsiu Chen, Wu-Shiun Tao, Hui-Fang Nai, Chen-Yi Yu, Chih-Hui Chiu","doi":"10.1080/15502783.2024.2414871","DOIUrl":"10.1080/15502783.2024.2414871","url":null,"abstract":"<p><strong>Background: </strong>This study investigated the effects of caffeinated chewing gum on fatigue index and 400-meter performance in trained sprinters.</p><p><strong>Methods: </strong>Nineteen participants (age: 20.9 ± 1.0 years; height: 175.6 ± 4.9 cm; mass: 66.5 ± 5.6 kg; training age: 7.9 ± 1.0 years) were randomly assigned to either a caffeine trial (CAF) or a placebo trial (PL) using a double-blind, randomized crossover design. The participants in the CAF trial chewed a gum containing 3 mg/kg of caffeine for a period of 10 minutes, while those in the PL trial chewed a gum containing a placebo with no caffeine. Following a 15-minute period of rest, the fatigue index was tested by six maximal 35-meter sprints with a 10-second rest between efforts. After this, at least 30 minutes of rest was permitted, during which time the participants engaged in brief warm-up activities prior to the commencement of the 400-meter sprint test. Saliva samples were collected before chewing gum, before the fatigue test and before 400-meters sprinting.</p><p><strong>Results: </strong>The fatigue index was significantly lower in the CAF trial compared to the PL trial (CAF: 8.1 ± 2.5%; PL: 9.6 ± 4.8%; <i>p</i> = 0.046, Cohen's d = 039). The CAF trial demonstrated significantly lower sprint time for the 300-400 meter segment (CAF: 14.73 ± 1.35 seconds; PL: 15.23 ± 1.30 seconds; <i>p</i> = 0.019, Cohen's d = 0.37) and total sprint time compared to the PL trial (CAF: 53.87 ± 2.88 seconds; PL: 54.68 ± 3.37 seconds; <i>p</i> = 0.003, Cohen's d = 0.27). Saliva caffeine and α-amylase concentration were significantly higher in the CAF trial compared to the PL trial (<i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>The present study demonstrated that caffeine gum supplementation prior to exercise significantly reduced the fatigue index and increased the capacity to maintain speed, particularly in the final 300 to 400 meters, as well as enhancing 400-meter sprint performance.</p>","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"21 1","pages":"2414871"},"PeriodicalIF":4.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11486005/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"6-week time-restricted eating improves body composition, maintains exercise performance, without exacerbating eating disorder in female DanceSport dancers.","authors":"Yanbing Zhou, Xian Guo, Zeyao Liu, Dan Sun, Yujie Liang, Hong Shen, Xinxin Li, Jinhao Mu, Jingying Liu, Guoxia Cao, Mengmeng Chen","doi":"10.1080/15502783.2024.2369613","DOIUrl":"10.1080/15502783.2024.2369613","url":null,"abstract":"<p><strong>Background: </strong>Despite the high risk of eating disorder (ED)-related attitudes and behaviors among female dancers, targeted scientific dietary regimens are currently inadequate. Time-restricted eating (TRE), a popular intermittent fasting protocol, has been shown to be effective in enhancing body composition and exercise performance in athletes. In this study, TRE was employed as a dietary regimen to improve body composition and exercise performance and address ED attitudes and behaviors in DanceSport dancers.</p><p><strong>Methods: </strong>Twenty female DanceSport dancers were recruited and divided into two groups: TRE (<i>n</i> = 10) and normal diet (ND) (<i>n</i> = 10). The TRE group consumed their self-selected necessary energy intake exclusively between 11 a.m. and 7 p.m. (utilizing a 16-hour fasting and 8-hour eating window) for 6 weeks, while the ND group maintained their regular dieting patterns. The consumption of water, black tea, or coffee without added sugar or milk was not restricted. Physical activity and calorie intake were systematically recorded during the TRE intervention. Body composition, aerobic and anaerobic performance, and ED attitudes and behaviors were assessed before and after the TRE intervention. The trial was registered in the Chinese Clinical Trial Registry under the identifier ChiCTR2200063780.</p><p><strong>Results: </strong>The fixed effects tests (<i>p</i> < 0.0001) and estimates for the intercept (<i>p</i> < 0.0001) of hunger level indicated a noticeable effect on the initial state of hunger during TRE. No significant differences were observed in ED attitudes or behaviors (<i>p</i> > 0.05). TRE resulted in a reduction in hip circumference (<i>p</i> = 0.039), fat mass (kg) (<i>p</i> = 0.0004), and body fat percentage (<i>p</i> = 0.0005), with no significant decrease in fat-free mass (<i>p</i> > 0.05). No significant improvement was observed in aerobic performance (<i>p</i> > 0.05). The average power (AP) (<i>p</i> = 0.01) and AP/Body weight ratio (<i>p</i> = 0.003) significantly increased. Additionally, the power drop decreased significantly (<i>p</i> = 0.019). Group-by-time interactions were observed for fat mass (kg) (<i>p</i> = 0.01), body fat percentage (<i>p</i> = 0.035), and AP/Body weight (<i>p</i> = 0.020).</p><p><strong>Conclusion: </strong>TRE can be considered a feasible nutritional strategy for DanceSport dancers, facilitating improvements in body composition without compromising aerobic and anaerobic exercise performance or exacerbating ED attitudes and behaviors. Moreover, TRE may facilitate more favorable physiological adaptations, potentially contributing to improved exercise performance.</p>","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"21 1","pages":"2369613"},"PeriodicalIF":4.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11195454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Drew E Gonzalez, Broderick L Dickerson, Sarah E Johnson, Kathryn E Woodruff, Megan Leonard, Choongsung Yoo, Joungbo Ko, Dante Xing, Victoria Martinez, Jacob Kendra, Landry Estes, Ryan J Sowinski, Chris J Rasmussen, Steven E Martin, Richard B Kreider
{"title":"Impact of astaxanthin supplementation on markers of cardiometabolic health and tactical performance among firefighters.","authors":"Drew E Gonzalez, Broderick L Dickerson, Sarah E Johnson, Kathryn E Woodruff, Megan Leonard, Choongsung Yoo, Joungbo Ko, Dante Xing, Victoria Martinez, Jacob Kendra, Landry Estes, Ryan J Sowinski, Chris J Rasmussen, Steven E Martin, Richard B Kreider","doi":"10.1080/15502783.2024.2427751","DOIUrl":"10.1080/15502783.2024.2427751","url":null,"abstract":"<p><strong>Rationale: </strong>Firefighters are at risk for cardiovascular disease due to occupational-related inflammation, oxidative stress, and lifestyle practices. Astaxanthin (AX) possesses anti-inflammatory/antioxidant and purported ergogenic properties. This study examined the impact of supplementing the diet with 12 mg/d AX for four weeks on markers of inflammation, oxidative stress, cardiometabolic health, exercise capacity, and occupation-related performance in career firefighters.</p><p><strong>Methods: </strong>In a randomized, double-blinded, placebo-controlled, crossover fashion, 15 male career firefighters (34.5 ± 7.4 years; 177.7 ± 7.0 cm; 95.6 ± 12.0 kg; 30.1 ± 2.9 kg/m<sup>2</sup>; 11.03 ± 6.85 years of service) ingested 12 mg/d of AX (AstaReal®, AstaReal AB, Nacka, SWE) or placebo (PLA) for four weeks while following a standardized resistance training program. After each treatment, testing sessions were completed to assess inflammatory markers, oxidative stress markers, cardiopulmonary exercise capacity, and performance to a fire ground test (FGT) consisting of nine fire suppressive activities. Data were analyzed using general linear model (GLM) analysis with repeated measures. Clinical significance was assessed via mean changes from baseline with 95% confidence intervals.</p><p><strong>Results: </strong>Analysis of mean percent changes from baseline revealed that AX supplementation lessened the inflammatory response to to performing an incremental maximal exercise test and attenuated increases in interleukin-1β, cortisol, and uric acid in response to performing fire suppressive activities compared to when they ingested PLA. However, most of these effects were within groups rather than between groups. Additionally, there was evidence that AX ingestion increased the ventilatory anaerobic threshold. Four weeks of AX supplementation did not significantly affect fasting markers of oxidative stress, blood lipids, performance during the FGT, general clinical chemistry panels, or self-reported side effects.</p><p><strong>Conclusions: </strong>Results provide some evidence that AX supplementation may help mediate occupation-related inflammation in response to high-intensity, short-duration exercise in firefighters. More research is warranted to determine if long-term supplementation can improve cardiometabolic risk in this population.</p><p><strong>Clinical trial registration: </strong>ISRCTN10901752.</p>","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"21 1","pages":"2427751"},"PeriodicalIF":4.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11583326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jason Tallis, Michael J Duncan, Neil D Clarke, Rhys O Morris, Ryan A Tamilio
{"title":"Are caffeine effects equivalent between different modes of administration: the acute effects of 3 mg.kg<sup>-1</sup> caffeine on the muscular strength and power of male university Rugby Union players.","authors":"Jason Tallis, Michael J Duncan, Neil D Clarke, Rhys O Morris, Ryan A Tamilio","doi":"10.1080/15502783.2024.2419385","DOIUrl":"https://doi.org/10.1080/15502783.2024.2419385","url":null,"abstract":"<p><strong>Background: </strong>There is growing interest in the potential of alternative modes of caffeine administration for enhancing sports performance. Given that alternative modes may evoke improved physical performance via distinct mechanisms, effects may not be comparable and studies directly comparing the erogenicity of alternative modes of caffeine administration are lacking. To address this knowledge gap, the present study evaluated the effect of 3 mg·kg<sup>-1</sup> caffeine delivered in anhydrous form via capsule ingestion, chewing gum or mouth rinsing on measures of muscular strength, power, and strength endurance in male Rugby Union players.</p><p><strong>Methods: </strong>Twenty-seven participants completed the study (Mean ± SD: Age 20 ± 2 yrs; daily caffeine consumption 188 ± 88 mg). Following assessments and reassessment of chest press (CP), shoulder press (SP), Deadlift (DL), and Squat (SQ) 1-repetition maximum (1RM) and familiarization to the experimental procedures, participants completed six experimental trials where they were administered 3 mg.kg<sup>-1</sup> caffeine (Caff) or placebo (Plac) capsule<sub>(CAP)</sub>, chewing gum<sub>(GUM)</sub> or mouth rinse<sub>(RINSE)</sub> in a randomized, double-blind and counterbalanced fashion prior to force platform assessment of countermovement jump, drop jump and isometric mid-thigh pull performance. Strength endurance was measured across two sets of CP, SP, DL, and SQ at 70% 1RM until failure. Pre-exercise perceptions of motivation and arousal were also determined.</p><p><strong>Results: </strong>Caffeine increased perceived readiness to invest mental effort (<i>p</i> = .038; ηp<sup>2</sup>=.156), countermovement jump height (<i>p</i> = .035; ηp<sup>2</sup>=.160) and SQ repetitions until failure in the first set (<i>p</i> < .001; d = .481), but there was no effect of delivery mode (<i>p</i> > .687; ηp<sup>2</sup><.015). Readiness to invest physical effort, felt arousal, drop jump height, countermovement jump, drop jump and isometric mid-thigh pull ground reaction force-time characteristics and repetitions until failure in CP, SP and DL were not affected by caffeine administration or mode of caffeine delivery (<i>p</i> > .0.052; ηp<sup>2</sup>< .136).</p><p><strong>Conclusion: </strong>3 mg.kg<sup>-1</sup> caffeine administered via capsule, gum or mouth rinse had limited effects on muscular strength, power, and strength endurance. Small effects of caffeine on CMJ height could not be explained by changes in specific ground reaction force-time characteristics and were not transferable to DJ performance, and effects specific to the SQ RTP exercise underpin the complexity in understanding effects of caffeine on muscular function. Novel modes of caffeine administration proposed to evoke benefits via distinct mechanisms did not offer unique effects, and the small number of effects demonstrated may have little translation to a single performance trial when data examining direct compariso","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"21 1","pages":"2419385"},"PeriodicalIF":4.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11500557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142502899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sofia Lopes, Madalena Cunha, João Guilherme Costa, Cíntia Ferreira-Pêgo
{"title":"Analysis of food supplements and sports foods consumption patterns among a sample of gym-goers in Portugal.","authors":"Sofia Lopes, Madalena Cunha, João Guilherme Costa, Cíntia Ferreira-Pêgo","doi":"10.1080/15502783.2024.2388077","DOIUrl":"10.1080/15502783.2024.2388077","url":null,"abstract":"<p><strong>Background: </strong>Gym-goers usually seek methods to improve performance, muscle gain, and overall health. One of the main strategies is including food supplements (FS) into their routine as aids to enhance their athletic capabilities and satisfy their nutritional needs. Thus, this study aimed to investigate and characterize the main FS and Sports Foods (SF) currently consumed, as well as the main reasons for their use and the source of advice in a group of gym-goers in the Lisbon Metropolitan Area (Portugal).</p><p><strong>Methods: </strong>A cross-sectional study was conducted, including 303 gym-goers from Lisbon, Portugal, who were 133 women and 170 males (30.8 ± 12.9 years old). Face-to-face interviews were used by qualified researchers to gather data.</p><p><strong>Results: </strong>Most of the interviewed athletes (71.95 %) took FS/SF, being men the main consumers. On average, 1.59 supplements were consumed per athlete. Logistic regression models indicated significant associations between age, gender, and motivations for gym attendance. While men and younger groups attended mainly for hypertrophy, women and older groups were focused on well-being. Protein (59.17 %) was the most used FS/SF, followed by creatine (41.28 %) and multivitamins (27.06 %). Men and younger individuals preferred protein and creatine, while older individuals focused more on specific vitamins and minerals. Women seemed to prefer L-carnitine and protein yogurts. Main sources of information included the internet, friends, and dietitians with notable gender and age-based preferences. Online stores were the main place of purchase. Monthly expenditures on FS/SF were not significantly affected by age or gender, but motivations for use had an influence.</p><p><strong>Conclusion: </strong>Most of the athletes interviewed took FS/SF, being men the major consumers. Protein was the principal FS/SF used, with online stores being the main place of purchase and the internet the primary source of information. Age and gender were key factors in adopted training, in the FS/SF chosen, and in the source of information selected. It is crucial that health professionals take primary responsibility for providing this guidance.</p>","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"21 1","pages":"2388077"},"PeriodicalIF":4.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11312987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141902119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sheena Y Smith, Carlos F Aylwin, Tyler F Daniels, Jennifer L Greer, Laura J Kunces, Loukia Lili, Stephen M Phipps, Caleb M Schmidt, Julian C Schmidt, Michael A Schmidt
{"title":"Kavalactones support motivation to move during intensive training in males preparing for military special operations forces.","authors":"Sheena Y Smith, Carlos F Aylwin, Tyler F Daniels, Jennifer L Greer, Laura J Kunces, Loukia Lili, Stephen M Phipps, Caleb M Schmidt, Julian C Schmidt, Michael A Schmidt","doi":"10.1080/15502783.2024.2377194","DOIUrl":"10.1080/15502783.2024.2377194","url":null,"abstract":"<p><strong>Background: </strong>Military special operators, elite athletes, and others requiring uninterrupted optimal performance currently lack options for sleep and mood support without performance-inhibiting effects. Kavalactones, derived from the root of the kava plant (<i>Piper methysticum</i> Forst), have been shown to elevate mood and wellbeing by producing a feeling of relaxation without addiction or cognitive impairment.</p><p><strong>Methods: </strong>In this placebo-controlled, crossover study (NCT05381025), we investigated the effects of 2 weeks of kavalactones use on cortisol (diurnal salivary), sleep (RSQ-W; Restorative Sleep Questionnaire, Weekly), mood (DASS-21; Depression Anxiety Stress Scale-21), and motivation state to expend (Move) or conserve (Rest) energy (CRAVE; Cravings for Rest and Volitional Energy Expenditure, Right Now) in a cohort of 15 healthy, physically fit young males engaged in a rigorous, two-a-day preparation class for special operations forces qualification.</p><p><strong>Results: </strong>Cortisol, sleep, and mood were within normal, healthy parameters in this cohort at baseline. This remained unchanged with kavalactones use with no significant findings of clinical interest. However, a statistically similar, positive slope for within-group Move scores was seen in both groups during kavalactones loading (first group Move slope 2.25, second group Move slope 3.29, <i>p</i> = 0.299). This trend was seen regardless of order and with no apparent effects on the Rest metric (all <i>p</i> ≥ 0.05). Moreover, a significant between-group difference appeared after 1 week of kavalactones use in the first phase (<i>p = </i>0.044) and persisted through the end of the first loading period (<i>p</i> = 0.022). Following the 10-day washout, this between-groups divergence remained significant (<i>p</i> = 0.038) but was reversed by 1 week after the crossover (<i>p = </i>0.072), with Move scores once again statistically similar between groups and compared to baseline at study end. Furthermore, the group taking kavalactones first never experienced a significant decrease in Move motivation state (lowest mean score 21.0, highest 28.6, all <i>p</i> ≥ 0.05), while the group receiving kavalactones in the last 2 weeks of the study had Move scores that were statistically lower than baseline (lowest mean score 8.6, highest 25.9, all <i>p</i> ≤ 0.05) at all time points but the last (<i>p</i> = 0.063) after 2 weeks of kavalactones exposure.</p><p><strong>Conclusions: </strong>We report a novel finding that kavalactones may support performance by maintaining or rescuing the desire to expend energy in the context of significant physical and mental strain in well-conditioned individuals, even in a context of already normal cortisol, sleep, and mood.</p>","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"21 1","pages":"2377194"},"PeriodicalIF":4.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11254123/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141620268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effects of nicotine withdrawal on exercise-related physical ability and sports performance in nicotine addicts: a systematic review and meta-analysis.","authors":"Kangzhe Bao, Kai Zheng, Xianxian Zhou, Baichao Chen, Zerui He, Danyang Zhu","doi":"10.1080/15502783.2024.2302383","DOIUrl":"10.1080/15502783.2024.2302383","url":null,"abstract":"<p><strong>Background: </strong>Previous research has established that nicotine withdrawal can ameliorate cardiovascular and pulmonary function in smokers. Nevertheless, the impact on physical fitness and athletic performance remains under-investigated.</p><p><strong>Objective: </strong>To evaluating the impacts of nicotine withdrawal on both exercise performance and exercise-associated physical capabilities in nicotine-dependent individuals.</p><p><strong>Study design: </strong>A comprehensive systematic review and meta-analysis.</p><p><strong>Data sources: </strong>The data was compiled from databases such as PubMed, Scopus, Web of Science, Cochrane Central, and EBSCO.</p><p><strong>Study selection: </strong>The selection criteria required studies to elucidate the effects of nicotine withdrawal on exercise performance or exercise-related physical abilities. Moreover, the selected studies needed to provide discernible experimental results.</p><p><strong>Data synthesis and analysis: </strong>The random effects model was employed in data analysis, utilizing the standardized mean difference (SMD) and the 95% confidence intervals (95% CIs) to estimate participants' exercise performance and physical abilities, referencing the Mean ±SD during baseline and withdrawal states.</p><p><strong>Results: </strong>Out of the selected studies, 10 trials were included, encompassing 13,538 participants aged 18 to 65 years. The findings suggest that nicotine withdrawal could potentially enhance sports performance (SMD = 0.45, 95% CI: 0.03 to 0.88; I^2 = 83%), particularly in terms of aerobic capacity. Short-term nicotine withdrawal (spanning 12 to 24 hours) might lead to a decline in participants' physical abilities in certain aspects like reaction time and sustained attention (SMD = -0.83, 95% CI: -1.91 to 0.25; I^2 = 79%), whereas long-term withdrawal (lasting 48 hours or more) demonstrated an opposing trend (SMD = 0.25, 95% CI: 0.12 to 0.39; I^2 = 81%). Overall, the results show that long-term nicotine withdrawal exhibited some positive impacts on sports performance and exercise-related physical ability, with the withdrawal duration being an indicator of subsequent physical performance.</p><p><strong>Conclusions: </strong>Mid- to long-term (≥3 months) nicotine withdrawal significantly improved the exercisers' exercise-related physical ability and sports performance. Conversely, short-term (≤24 hours) nicotine withdrawal considerably hampered exercisers' performance and physical cognition. It is suggested that exercises avoid abrupt nicotine cessation prior to competitions, as long-term nicotine withdrawal has been shown to significantly enhance exercise-related physiological capacities and athletic performance. By referring to existing literatures we also found that athletes with existing nicotine addiction may could consume nicotine 15-30 minutes before competition to enhance athletic performance and physical function.PROSPERO registration number CRD4202341138","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"21 1","pages":"2302383"},"PeriodicalIF":5.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10791090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139425016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rhiannon J Brenner, Kiran A Balan, Marie P L Andersen, Emmanuel Dugrenot, Xavier C E Vrijdag, Hanna Van Waart, Frauke Tillmans
{"title":"A review of nutritional recommendations for scuba divers.","authors":"Rhiannon J Brenner, Kiran A Balan, Marie P L Andersen, Emmanuel Dugrenot, Xavier C E Vrijdag, Hanna Van Waart, Frauke Tillmans","doi":"10.1080/15502783.2024.2402386","DOIUrl":"10.1080/15502783.2024.2402386","url":null,"abstract":"<p><strong>Background: </strong>Scuba diving is an increasingly popular activity that involves the use of specialized equipment and compressed air to breathe underwater. Scuba divers are subject to the physiological consequences of being immersed in a high-pressure environment, including, but not limited to, increased work of breathing and kinetic energy expenditure, decreased fluid absorption, and alteration of metabolism. Individual response to these environmental stressors may result in a differential risk of decompression sickness, a condition thought to result from excess nitrogen bubbles forming in a diver's tissues. While the mechanisms of decompression sickness are still largely unknown, it has been postulated that this response may further be influenced by the diver's health status. Nutritional intake has direct relevancy to inflammation status and oxidative stress resistance, both of which have been associated with increased decompression stress. While nutritional recommendations have been determined for saturation divers, these recommendations are likely overly robust for recreational divers, considering that the differences in time spent under pressure and the maximum depth could result nonequivalent energetic demands. Specific recommendations for recreational divers remain largely undefined.</p><p><strong>Methods: </strong>This narrative review will summarize existing nutritional recommendations and their justification for recreational divers, as well as identify gaps in research regarding connections between nutritional intake and the health and safety of divers.</p><p><strong>Results: </strong>Following recommendations made by the Institute of Medicine and the Naval Medical Research Institute of Bethesda, recreational divers are advised to consume ~170-210 kJ·kg<sup>-1</sup> (40-50 kcal·kg<sup>-1</sup>) body mass, depending on their workload underwater, in a day consisting of 3 hours' worth of diving above 46 msw. Recommendations for macronutrient distribution for divers are to derive 50% of joules from carbohydrates and less than 30% of joules from fat. Protein consumption is recommended to reach a minimum of 1 g of protein·kg<sup>-1</sup> of body mass a day to mitigate loss of appetite while meeting energetic requirements. All divers should take special care to hydrate themselves with an absolute minimum of 500 ml of fluid per hour for any dive longer than 3 hours, with more recent studies finding 0.69 liters of water two hours prior to diving is most effective to minimize bubble loads. While there is evidence that specialized diets may have specific applications in commercial or military diving, they are not advisable for the general recreational diving population considering the often extreme nature of these diets, and the lack of research on their effectiveness on a recreational diving population.</p><p><strong>Conclusions: </strong>Established recommendations do not account for changes in temperature, scuba equipment, depth, ","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"21 1","pages":"2402386"},"PeriodicalIF":4.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11423531/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142308041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael B La Monica, Betsy Raub, Shelley Hartshorn, Ashley L Gustat, Jodi Grdic, Trevor O Kirby, Jeremy R Townsend, Jen Sandrock, Tim N Ziegenfuss
{"title":"The effects of AG1® supplementation on the gut microbiome of healthy adults: a randomized, double-blind, placebo-controlled clinical trial.","authors":"Michael B La Monica, Betsy Raub, Shelley Hartshorn, Ashley L Gustat, Jodi Grdic, Trevor O Kirby, Jeremy R Townsend, Jen Sandrock, Tim N Ziegenfuss","doi":"10.1080/15502783.2024.2409682","DOIUrl":"10.1080/15502783.2024.2409682","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to examine the effect of a commercially available multi-ingredient powder (AG1<sup>Ⓡ</sup>) on the gut microbiome and assess the impact of AG1<sup>Ⓡ</sup> on GI tolerability and other clinical safety markers in healthy men and women.</p><p><strong>Methods: </strong>Using a double-blind, randomized, two-arm, placebo-controlled, parallel design, we examined a 4-week daily supplementation regimen of AG1<sup>Ⓡ</sup> vs. placebo (PL). Fifteen men and 15 women provided stool samples for microbiome analysis, questionnaires for digestive quality of life (DQLQ), and completed visual analog scales (VAS) and Bristol stool charts to assess stool consistency and bowel frequency before and after the 4-week intervention. Participant's blood work (CBC, CMP, and lipid panel) was also assessed before and after the 4-week intervention. Alpha diversity was determined by Shannon and Chao1 index scores and evaluated by a two-way ANOVA, beta diversity in taxonomic abundances and functional pathways was visualized using partial least squares-discriminant analyses and statistically evaluated by PERMANOVA. To identify key biomarkers, specific feature differences in taxonomic relative abundance and normalized functional pathway counts were analyzed by linear discriminant analysis (LDA) effect size (LEfSe). Questionnaires, clinical safety markers, and hemodynamics were evaluated by mixed factorial ANOVAs with repeated measures. This study was registered on clinicaltrials.gov (NCT06181214).</p><p><strong>Results: </strong>AG1<sup>Ⓡ</sup> supplementation enriched two probiotic taxa (<i>Lactobacillus acidophilus</i> and <i>Bifidobacterium bifidum</i>) that likely stem from the probiotics species that exist in the product, as well as <i>L.</i> <i>lactis</i> CH_LC01 and <i>Acetatifactor</i> sp900066565 ASM1486575v1 while reducing <i>Clostridium</i> sp000435835. Regarding community function, AG1<sup>Ⓡ</sup> showed an enrichment of two functional pathways while diminishing none. Alternatively, the PL enriched six, but diminished five functional pathways. Neither treatment negatively impacted the digestive quality of life via DQLQ, bowel frequency via VAS, or stool consistency via VAS and Bristol. However, there may have been a greater improvement in the DQLQ score (+62.5%, <i>p</i> = 0.058, d = 0.73) after four weeks of AG1<sup>Ⓡ</sup> supplementation compared to a reduction (-50%) in PL. Furthermore, AG1<sup>Ⓡ</sup> did not significantly alter clinical safety markers following supplementation providing evidence for its safety profile.</p><p><strong>Conclusions: </strong>AG1<sup>Ⓡ</sup> can be consumed safely by healthy adults over four weeks with a potential beneficial impact in their digestive symptom quality of life.</p>","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"21 1","pages":"2409682"},"PeriodicalIF":4.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11445888/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}