Journal of the International Society of Sports Nutrition最新文献

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Bioinformatic identification of important roles of COL1A1 and TNFRSF12A in cartilage injury and osteoporosis.
IF 4.5 2区 医学
Journal of the International Society of Sports Nutrition Pub Date : 2025-12-01 Epub Date: 2025-01-23 DOI: 10.1080/15502783.2025.2454641
Muzi Liu, Shiguo Gong, Xin Sheng, Zihong Zhang, Xichun Wang
{"title":"Bioinformatic identification of important roles of COL1A1 and TNFRSF12A in cartilage injury and osteoporosis.","authors":"Muzi Liu, Shiguo Gong, Xin Sheng, Zihong Zhang, Xichun Wang","doi":"10.1080/15502783.2025.2454641","DOIUrl":"10.1080/15502783.2025.2454641","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to identify the key regulatory mechanisms of cartilage injury and osteoporosis through bioinformatics methods, and to provide a new theoretical basis and molecular targets for the diagnosis and treatment of the disease.</p><p><strong>Methods: </strong>Microarray data for cartilage injury (GSE129147) and osteoporosis (GSE230665) were first downloaded from the GEO database. Differential expression analysis was applied to identify genes that were significantly up-or down-regulated in the cartilage injury and osteoporosis samples. These genes were subjected to GO enrichment analysis and KEGG pathway analysis. In addition, we employed SVA and RRA methods to merge the two sets of data, eliminating batch effects and enhancing the statistical power of the analysis. Through WGCNA, we identified gene modules that were closely associated with disease phenotypes and then screened for key genes that intersected with differentially expressed genes. The diagnostic value of these genes as potential biomarkers was evaluated by ROC analysis. Moreover, we performed an immune infiltration analysis to explore the correlation between these core genes and immune cell infiltration.</p><p><strong>Results: </strong>We performed GO enrichment analysis and KEGG pathway analysis of genes significantly up-or down-regulated in cartilage injury and osteoporosis samples. Important biological processes, cellular components and molecular functions, and key metabolic or signaling pathways associated with osteoporosis and cartilage injury were identified. Through WGCNA, we identified gene modules that were closely associated with the disease phenotype, from which we then screened for key genes that intersected with differentially expressed genes. Ultimately, we focused on two identified core genes, COL1A1 and TNFRSF12A, and assessed the diagnostic value of these genes as potential biomarkers by ROC analysis. Meanwhile, GSVA provided an in-depth view of the role of these genes in disease-specific biological pathways. Immune infiltration analysis further revealed the possible key role of COL1A1 and TNFRSF12A in regulating immune cell infiltration in osteoporosis and cartilage injury.</p><p><strong>Conclusion: </strong>COL1A1 and TNFRSF12A as key regulatory molecules in osteoporosis and cartilage injury.</p>","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"22 1","pages":"2454641"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of protein supplementation during pilates training on body composition, core muscle endurance, and joint flexibility in trained women: a randomized controlled trial.
IF 4.5 2区 医学
Journal of the International Society of Sports Nutrition Pub Date : 2025-12-01 Epub Date: 2025-02-26 DOI: 10.1080/15502783.2025.2472891
Christina Karpouzi, Antigoni Kypraiou, Vassilis Mougios, Anatoli Petridou
{"title":"Effects of protein supplementation during pilates training on body composition, core muscle endurance, and joint flexibility in trained women: a randomized controlled trial.","authors":"Christina Karpouzi, Antigoni Kypraiou, Vassilis Mougios, Anatoli Petridou","doi":"10.1080/15502783.2025.2472891","DOIUrl":"10.1080/15502783.2025.2472891","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Pilates is a popular type of exercise, aimed at improving core muscle strength and endurance, core stability, and joint flexibility through a variety of whole-body exercises. Research has shown that Pilates improves body composition, muscle endurance, and joint flexibility. Adequate protein intake is a key factor in supporting the adaptive response of skeletal muscle to exercise training. However, whether protein supplementation augments the adaptations to Pilates training remains unknown. Thus, the aim of the present study was to investigate the effects of protein supplementation during Pilates training on body composition, core muscle endurance, and joint flexibility in trained women.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Nineteen Pilates-trained women (31 ± 9 y) performed 10 weeks of Pilates training using the Reformer and Cadillac apparatuses, at least 2 times per week. Participants were randomly allocated to either a placebo (&lt;i&gt;n&lt;/i&gt; = 10) or protein supplementation group (&lt;i&gt;n&lt;/i&gt; = 9) in a quadruple-blind (participants, intervention providers, investigators, and outcome assessors) design. Participants received 0.6 g of maltodextrin or whey protein per kg body weight daily, respectively. Habitual dietary intake was monitored throughout the study. Before and after the intervention, anthropometric measures (body weight, body mass index, waist and hip circumferences), body composition [through full-scan dual-energy X-ray absorptiometry (DXA) and multifrequency bioelectrical impedance analysis (BIA)], core muscle endurance (through the McGill's torso muscular endurance test battery), and joint flexibility (through the sit-and-reach test) were assessed. Data were analyzed by 2-way ANOVA (supplement × time) with repeated measures on time. Common DXA and BIA variables (whole-body fat and lean mass) were compared through paired Student's t tests and subjected to Pearson's correlation analysis. The level of statistical significance was set at α = 0.05.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Participants received, on average, 1.3 g protein/kg body weight/day from their habitual diet. After 10 weeks of Pilates training and regardless of supplementation, body fat (assessed by BIA) and hip circumference decreased; lean mass, total water, and extracellular water (by BIA) increased; and arm lean mass, trunk bone mineral content, and trunk bone area (by DXA) increased (all &lt;i&gt;p&lt;/i&gt; &lt; 0.05). The common BIA and DXA variables were highly correlated (&lt;i&gt;r&lt;/i&gt; &gt; 0.78, &lt;i&gt;p&lt;/i&gt; &lt; 0.001) and did not differ pre-intervention (&lt;i&gt;p&lt;/i&gt; &gt; 0.1), although they differed post-intervention (&lt;i&gt;p&lt;/i&gt; &lt; 0.001), with BIA overestimating lean mass compared with DXA. Core muscle endurance and joint flexibility increased with training (&lt;i&gt;p&lt;/i&gt; &lt; 0.05), with no effect of supplementation.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Ten weeks of Pilates training improved core muscle endurance, joint flexibility, and aspects of body composition in healthy trained women, ","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"22 1","pages":"2472891"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143516024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
International society of sports nutrition position stand: β-hydroxy-β-methylbutyrate (HMB). 国际运动营养学会立场:β-羟基-β-甲基丁酸酯(HMB)。
IF 4.5 2区 医学
Journal of the International Society of Sports Nutrition Pub Date : 2025-12-01 Epub Date: 2024-12-19 DOI: 10.1080/15502783.2024.2434734
John A Rathmacher, Lisa M Pitchford, Jeffrey R Stout, Jeremy R Townsend, Ralf Jäger, Richard B Kreider, Bill I Campbell, Chad M Kerksick, Patrick S Harty, Darren G Candow, Brandon M Roberts, Shawn M Arent, Douglas S Kalman, Jose Antonio
{"title":"International society of sports nutrition position stand: β-hydroxy-β-methylbutyrate (HMB).","authors":"John A Rathmacher, Lisa M Pitchford, Jeffrey R Stout, Jeremy R Townsend, Ralf Jäger, Richard B Kreider, Bill I Campbell, Chad M Kerksick, Patrick S Harty, Darren G Candow, Brandon M Roberts, Shawn M Arent, Douglas S Kalman, Jose Antonio","doi":"10.1080/15502783.2024.2434734","DOIUrl":"10.1080/15502783.2024.2434734","url":null,"abstract":"&lt;p&gt;&lt;p&gt;Position Statement: The International Society of Sports Nutrition (ISSN) bases the following position stand on an analysis of the literature regarding the effects of β-Hydroxy-β-Methylbutyrate (HMB). The following 12 points have been approved by the Research Committee of the Society: 1. HMB is a metabolite of the amino acid leucine that is naturally produced in both humans and other animals. Two forms of HMB have been studied: Calcium HMB (HMB-Ca) and a free acid form of HMB (HMB-FA). HMB-FA appears to lead to increased appearance of HMB in the bloodstream when compared to HMB-Ca, though recent results are mixed. 2. The available safety/toxicity data suggest that chronic HMB-Ca and HMB-FA consumption are safe for oral HMB supplementation in humans up to at least one year. 3. There are no negative effects of HMB-Ca and HMB-FA on glucose tolerance and insulin sensitivity in humans. There may be improvements in glucose metabolism in younger adults. 4. The primary mode of action of HMB appears to be through its dual mechanism to enhance muscle protein synthesis and suppress muscle protein breakdown. HMB's activation of mTORC1 is independent of the leucine-sensing pathway (Sestrin2-GATOR2 complex). 5. HMB may help reduce muscle damage and promote muscle recovery, which can promote muscle growth/repair. HMB may also have anti-inflammatory effects, which could contribute to reducing muscle damage and soreness. 6. HMB consumption in close proximity to an exercise bout may be beneficial to increase muscle protein synthesis and attenuate the inflammatory response. HMB can provide a beneficial physiological effect when consumed both acutely and chronically in humans. 7. Daily HMB supplementation (38 mg/kg body weight) in combination with exercise training may improve body composition through increasing lean mass and/or decreasing fat mass with benefits in participants across age, sex, and training status. The most pronounced of these improvements in body composition with HMB have been observed in studies with robust resistance training programs and dietary control. 8. HMB may improve strength and power in untrained individuals, but its performance benefits in trained athletes are mixed and increase with an increase in study duration (&gt;6 weeks). HMB's beneficial effects on athletic performance are thought to be driven by improved recovery. 9. HMB supplementation appears to potentially have a positive impact on aerobic performance, especially in trained athletes. The mechanisms of the effects are unknown. 10. HMB supplementation may be important in a non-exercising sedentary and aging population to improve muscle strength, functionality, and muscle quality. The effects of HMB supplementation with exercise are varied, but the combination may have a beneficial effect on the treatment of age-associated sarcopenia under select conditions. 11. HMB may be effective in countering muscle disuse atrophy during periods of inactivity due to illness or injury. The ","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"22 1","pages":"2434734"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11740297/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of time restricted eating and resistance training on body composition and mood profiles among young adults with overweight/obesity: a randomized controlled trial.
IF 4.5 2区 医学
Journal of the International Society of Sports Nutrition Pub Date : 2025-12-01 Epub Date: 2025-03-19 DOI: 10.1080/15502783.2025.2481127
Tingting Cui, Yichao Sun, Weibing Ye, Yubo Liu, Mallikarjuna Korivi
{"title":"Efficacy of time restricted eating and resistance training on body composition and mood profiles among young adults with overweight/obesity: a randomized controlled trial.","authors":"Tingting Cui, Yichao Sun, Weibing Ye, Yubo Liu, Mallikarjuna Korivi","doi":"10.1080/15502783.2025.2481127","DOIUrl":"10.1080/15502783.2025.2481127","url":null,"abstract":"<p><strong>Background/objective: </strong>Dietary restriction or exercise regimens can promote weight loss or physical fitness among patients with obesity. However, intervention-associated adverse effects may impede patients' motivation to participate in dietary/exercise interventions. We examined the effects of time restricted eating (TRE) with or without resistance training (RT) on body composition, mood profile, and sleep quality in young college adults with overweight or obesity.</p><p><strong>Methods: </strong>Fifty-four young college students with overweight/obesity were randomized into control (CON), TRE, RT, and TRE plus RT (TRE+RT) trials. The TRE trials restricted to an eating window of 10-hour/day for 8-week. The RT trials performed supervised resistance exercise, while the control trial maintained a regular lifestyle. Changes in body composition variables, blood pressure, mood status, and sleep quality were measured before and after the intervention.</p><p><strong>Results: </strong>TRE intervention alone or in combination with RT significantly (<i>p</i> < 0.01) decreased body weight (>2 kg) and BMI (~1 kg/m<sup>2</sup>) in adults with overweight/obesity. Both RT alone and combined with TRE substantially decreased fat mass by 1.1 ± 0.5 and 3.2 ± 0.4 kg, respectively. The decreased fat mass was greater in the combination trial than in the RT trial, whereas TRE alone had no effect. In contrast, fat-free mass was significantly (<i>p</i> < 0.01) decreased with TRE (-2.3 ± 06 kg), increased with RT (1.6 ± 0.3 kg), and was stably maintained with combination interventions. The reduced waist and hip circumferences in the TRE (<i>p</i> < 0.01) were similar to those in the TRE+RT trials, however, RT alone had no effect. Time and group interaction showed a large effect size (partial eta squared) for all body composition variables. In addition, RT with or without TRE notably decreased diastolic blood pressure (RT: -5.5 ± 1.9 mmHg, TRE+RT: -4.1 ± 1.5 mmHg, <i>p</i> < 0.05). Mild anxiety levels at baseline in RT (4.8 ± 2.6) and TRE+RT (4.1 ± 3) trials were found to be normal at postintervention in TRE+RT (3.6 ± 1.7) but not in RT (5.6 ± 3.5). No depression or stress was recorded among the participants during the intervention. The reported poor sleep quality among participants at baseline was significantly improved with RT (4.8 ± 2.9; <i>p</i> < 0.05), and tended to improve with TRE+RT interventions (4.5 ± 1.9).</p><p><strong>Conclusions: </strong>10-hour TRE is beneficial for weight/fat loss without affecting mood status. However, TRE combined with RT might be more effective for weight/fat loss, maintaining muscle mass, and good quality of sleep among young adults with overweight or obesity.</p>","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"22 1","pages":"2481127"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in taste and odor sensitivities during repeated bicycle ergometer exercises. 在重复的自行车测力器运动中味觉和气味敏感性的变化。
IF 4.5 2区 医学
Journal of the International Society of Sports Nutrition Pub Date : 2025-12-01 Epub Date: 2024-12-16 DOI: 10.1080/15502783.2024.2441769
Masataka Narukawa, Kensuke Nojiri, Rina Matsuda, Momo Murata, Seiji Sakate, Sachiko Kuga, Hidetoshi Ue
{"title":"Changes in taste and odor sensitivities during repeated bicycle ergometer exercises.","authors":"Masataka Narukawa, Kensuke Nojiri, Rina Matsuda, Momo Murata, Seiji Sakate, Sachiko Kuga, Hidetoshi Ue","doi":"10.1080/15502783.2024.2441769","DOIUrl":"10.1080/15502783.2024.2441769","url":null,"abstract":"<p><strong>Background: </strong>Effective nutritional support is essential for maintaining good performance during exercise. Taste and olfaction are key senses for food intake, and understanding how their sensitivities change during exercise is important for effective nutritional support. However, the effects of exercise on taste and odor sensitivities remain unclear. This study aimed to investigate changes in taste and odor sensitivities during repeated endurance exercise using a bicycle ergometer.</p><p><strong>Methods: </strong>A total of 20 women (mean age; 21.6 ± 0.2 years) participated in the study, completing four 60-minute segments, each comprising 50 minutes of bicycle ergometer exercise at an exercise intensity of 60% heart rate reserve and a 10-minute sensory test. The sensory tests were conducted five times in total: after each exercise segment and once before exercise as a control. Four concentrations (×0.5, ×0.75, ×1, and × 1.25) of a commercially available isotonic beverage were used as taste samples, and the subjects evaluated the taste intensity, preference, and odor intensity. Four types of food odorants were used as odor samples, and the subjects rated their preference. The subjects also reported their perceived fatigue levels during the taste and odor tests. Fatigue levels and taste intensity were rated using a 100-mm visual analogue scale, and taste and odor preferences and odor intensity were evaluated using a scoring method.</p><p><strong>Results: </strong>The degree of physical fatigue significantly increased with each successive bicycle exercise segment. The taste intensity and preference for beverages with higher concentrations increased as the number of exercise segments increased, showing a significant increase in taste intensity for the × 1.25 solution in the final segment compared with before the tests. On the other hand, no significant effect was observed on the perceived odor intensity of the isotonic beverages. Similarly, there was no significant effect on the preference for odor samples due to repeated exercise.</p><p><strong>Conclusions: </strong>These results suggest that taste sensitivity may change with prolonged exercise. Additionally, since odor intensity and preference were not significantly affected by repeated exercise, odor sensitivity may be less impacted by exercise than taste sensitivity.</p>","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"22 1","pages":"2441769"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11654038/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142837209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment on "Association of low muscle mass index and sarcopenic obesity with knee osteoarthritis: a systematic review and meta-analysis".
IF 4.5 2区 医学
Journal of the International Society of Sports Nutrition Pub Date : 2025-12-01 Epub Date: 2025-02-28 DOI: 10.1080/15502783.2025.2470230
Jinxiang Peng, Haozhu Chen
{"title":"Comment on \"Association of low muscle mass index and sarcopenic obesity with knee osteoarthritis: a systematic review and meta-analysis\".","authors":"Jinxiang Peng, Haozhu Chen","doi":"10.1080/15502783.2025.2470230","DOIUrl":"10.1080/15502783.2025.2470230","url":null,"abstract":"","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"22 1","pages":"2470230"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11873926/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143523751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Part II. Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show? 第二部分。关于补充肌酸的常见问题和误解:科学证据真正显示了什么?
IF 4.5 2区 医学
Journal of the International Society of Sports Nutrition Pub Date : 2025-12-01 Epub Date: 2024-12-25 DOI: 10.1080/15502783.2024.2441760
Jose Antonio, Ann F Brown, Darren G Candow, Philip D Chilibeck, Stacey J Ellery, Scott C Forbes, Bruno Gualano, Andrew R Jagim, Chad Kerksick, Richard B Kreider, Sergej M Ostojic, Eric S Rawson, Michael D Roberts, Hamilton Roschel, Abbie E Smith-Ryan, Jeffrey R Stout, Mark A Tarnopolsky, Trisha A VanDusseldorp, Darryn S Willoughby, Tim N Ziegenfuss
{"title":"Part II. Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?","authors":"Jose Antonio, Ann F Brown, Darren G Candow, Philip D Chilibeck, Stacey J Ellery, Scott C Forbes, Bruno Gualano, Andrew R Jagim, Chad Kerksick, Richard B Kreider, Sergej M Ostojic, Eric S Rawson, Michael D Roberts, Hamilton Roschel, Abbie E Smith-Ryan, Jeffrey R Stout, Mark A Tarnopolsky, Trisha A VanDusseldorp, Darryn S Willoughby, Tim N Ziegenfuss","doi":"10.1080/15502783.2024.2441760","DOIUrl":"10.1080/15502783.2024.2441760","url":null,"abstract":"<p><p>Creatine monohydrate supplementation (CrM) is a safe and effective intervention for improving certain aspects of sport, exercise performance, and health across the lifespan. Despite its evidence-based pedigree, several questions and misconceptions about CrM remain. To initially address some of these concerns, our group published a narrative review in 2021 discussing the scientific evidence as to whether CrM leads to water retention and fat accumulation, is a steroid, causes hair loss, dehydration or muscle cramping, adversely affects renal and liver function, and if CrM is safe and/or effective for children, adolescents, biological females, and older adults. As a follow-up, the purpose of this paper is to evaluate additional questions and misconceptions about CrM. These include but are not limited to: 1. Can CrM provide muscle benefits without exercise? 2. Does the timing of CrM really matter? 3. Does the addition of other compounds with CrM enhance its effectiveness? 4. Does CrM and caffeine oppose each other? 5. Does CrM increase the rates of muscle protein synthesis or breakdown? 6. Is CrM an anti-inflammatory intervention? 7. Can CrM increase recovery following injury, surgery, and/or immobilization? 8. Does CrM cause cancer? 9. Will CrM increase urine production? 10. Does CrM influence blood pressure? 11. Is CrM safe to consume during pregnancy? 12. Does CrM enhance performance in adolescents? 13. Does CrM adversely affect male fertility? 14. Does the brain require a higher dose of CrM than skeletal muscle? 15. Can CrM attenuate symptoms of sleep deprivation? 16. Will CrM reduce the severity of and/or improve recovery from traumatic brain injury? Similar to our 2021 paper, an international team of creatine research experts was formed to perform a narrative review of the literature regarding CrM to formulate evidence-based responses to the aforementioned misconceptions involving CrM.</p>","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"22 1","pages":"2441760"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
General and sport-specific nutrition knowledge and behaviors of adolescent athletes.
IF 4.5 2区 医学
Journal of the International Society of Sports Nutrition Pub Date : 2025-12-01 Epub Date: 2025-03-10 DOI: 10.1080/15502783.2025.2477060
Ronald L Gibbs, Tyler Brian Becker
{"title":"General and sport-specific nutrition knowledge and behaviors of adolescent athletes.","authors":"Ronald L Gibbs, Tyler Brian Becker","doi":"10.1080/15502783.2025.2477060","DOIUrl":"10.1080/15502783.2025.2477060","url":null,"abstract":"<p><strong>Introduction: </strong>Most youth do not meet national nutrition recommendations and overconsume high-calorie, low nutrient-dense foods. Adequate nutritional intake is crucial for growth and development. Nutrition practices play a key role in sports performance and recovery. Nutritional knowledge can affect eating patterns. However, there is limited research on general and sport-specific nutrition knowledge and behaviors of adolescent athletes.</p><p><strong>Purpose: </strong>To examine general and sport-specific nutrition knowledge and behaviors of adolescent athletes.</p><p><strong>Methods: </strong>Adolescent athletes were assessed on nutrition knowledge and general and sport-specific nutrition behaviors, including food group consumption, hydration practices, and sport supplement use. Gender differences in general and sport-specific nutrition behaviors were compared using a Mann-Whitney U test. Odds ratios and logistic regression, controlling for age, ethnicity, and years in sport participation were used to determine differences in correct responses between genders. Significance was set at the <i>p</i> < 0.05 level.</p><p><strong>Results: </strong>One hundred and ninety-four athletes (<i>n</i> = 63 male, <i>n</i> = 132 female, mean age = 14.9 ± 1.63 years) were assessed. Differences in nutrition behaviors were found in fruit, dairy, and sugary beverage consumption between genders. Male athletes were more likely to monitor hydration and use sports supplements. Both males and females scored less than 50% on both general and sport-specific knowledge questions.</p><p><strong>Conclusion: </strong>Adolescent athletes report lower than recommended food group consumption and lack knowledge of general and sport-specific nutrition information. Improvements in these areas can play a significant role in the health and performance of adolescent athletes.</p>","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"22 1","pages":"2477060"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11894754/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex differences in the associations of dietary protein intake with lean mass and grip strength in children and adolescents.
IF 4.5 2区 医学
Journal of the International Society of Sports Nutrition Pub Date : 2025-12-01 Epub Date: 2025-02-24 DOI: 10.1080/15502783.2025.2471471
Yanfei Wang, Dan Sun, Zhongxin Zhu
{"title":"Sex differences in the associations of dietary protein intake with lean mass and grip strength in children and adolescents.","authors":"Yanfei Wang, Dan Sun, Zhongxin Zhu","doi":"10.1080/15502783.2025.2471471","DOIUrl":"10.1080/15502783.2025.2471471","url":null,"abstract":"<p><strong>Background: </strong>Childhood and adolescence are critical developmental periods during which dietary protein plays a crucial role in musculoskeletal health. While the significance of protein in muscle development is well acknowledged, the complex associations between dietary protein intake and musculoskeletal parameters during these stages remain incompletely elucidated.</p><p><strong>Methods: </strong>This cross-sectional study utilized data from the National Health and Nutrition Examination Survey (NHANES) 2011-2014 cycles, including 3,455 children and adolescents aged 8-19 years. Dietary protein intake was assessed through two 24-hour dietary recalls. Appendicular lean mass index (ALMI) and combined grip strength were measured as indicators of musculoskeletal health. Multivariate linear regression models and smooth curve fitting techniques were employed to analyze associations.</p><p><strong>Results: </strong>Higher protein intake was positively associated with both ALMI (β = 0.003, 95% CI: 0.002, 0.004, <i>p</i> < 0.001) and combined grip strength (β = 0.043, 95% CI: 0.027, 0.058, <i>p</i> < 0.001) in fully adjusted models. Notably, sex-specific effects were observed, with stronger associations in boys, particularly in the 8-11 years age group.</p><p><strong>Conclusions: </strong>This study reveals significant positive associations between dietary protein intake and musculoskeletal health indicators in children and adolescents, with pronounced sex-specific effects. These findings underscore the importance of adequate protein intake during critical developmental periods and may inform targeted nutritional strategies for optimizing long-term musculoskeletal health.</p>","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"22 1","pages":"2471471"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864004/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143492586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Survey of nutritional intake status in college baseball players.
IF 4.5 2区 医学
Journal of the International Society of Sports Nutrition Pub Date : 2025-12-01 Epub Date: 2025-02-03 DOI: 10.1080/15502783.2025.2459090
Yoko Iio, Hana Kozai, Mamoru Tanaka, Yukihiro Mori, Manato Seguchi, Yuka Aoyama, Morihiro Ito
{"title":"Survey of nutritional intake status in college baseball players.","authors":"Yoko Iio, Hana Kozai, Mamoru Tanaka, Yukihiro Mori, Manato Seguchi, Yuka Aoyama, Morihiro Ito","doi":"10.1080/15502783.2025.2459090","DOIUrl":"10.1080/15502783.2025.2459090","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Diet is closely related to exercise performance. To improve athletes' performance and manage their condition, it is important to get sufficient energy and various nutrients. Thus, it is necessary that athletes understand their nutritional intake status to improve performance and maintain health. This study aimed to explore the nutritional intake status of college baseball players using the Food Frequency Questionnaire (FFQ). Furthermore, the characteristics of their nutritional intake status with respect to athletic performance were evaluated. The result of this studyprovide an opportunity for many under-developed college athletes with irregular lifestyles to recognize and improve their nutritional problems.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;In October 2022, a questionnaire survey of 116 male members of a college baseball club was conducted. Of whom, 100 (94.3%) members responded to the survey and 92 (92.0%) provided valid responses. The survey items included basic characteristics such as college grade and type of living arrangement, and information on living conditions, e.g. whether the participant ate breakfast. Nutritional intake was evaluated using the FFQ. Players were divided into the first (regular players in official games), second (bench players in official games), third (players who may join the second or higher team in the future), and fourth teams (players who do not belong to the first to third teams); these categories were used as a marker of performance level. The Kruskal-Wallis test was used to analyze the association between the performance levels of baseball players and the intake of each nutrient and food group obtained by the FFQ. For items that showed a significant association, inter-group comparison was performed using the Dunn-Bonferroni method.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Carbohydrate intake was greater in the second team compared with the third and fourth teams; saturated and monounsaturated fatty acid intake was higher in the third team compared with the fourth team. Calcium, zinc, copper, manganese, insoluble dietary fiber, iodine, and molybdenum intake was higher in the second team compared with the fourth team. Intake of grains, sugar, dairy, and total energy was significantly higher in the second team compared with the fourth team. However, the protein intake ratio was significantly lower in the second team compared with the fourth team. Overall, energy deficiency and associated deficiencies in protein, fat, and carbohydrate were observed, in addition to dietary fiber and calcium deficiencies. The intake of several food groups appeared inadequate, such as potatoes, beans, vegetables, fruits, eggs, milk, and fats.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The study showed deficiencies in the amount of energy and nutrients such as protein, fat, and carbohydrate in college baseball players. Differences in the intake of carbohydrate, calcium, and insoluble dietary fiber among different perform","PeriodicalId":17400,"journal":{"name":"Journal of the International Society of Sports Nutrition","volume":"22 1","pages":"2459090"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11792141/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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