2011 IEEE International Symposium on IT in Medicine and Education最新文献_第4页

The Training Teaching Management Informatization study and system realization based on web service 基于web服务的培训教学管理信息化研究与系统实现

2011 IEEE International Symposium on IT in Medicine and Education Pub Date : 2011-12-01 DOI: 10.1109/ITIME.2011.6130910

Feng Yang, Yufeng Zhao

引用次数: 0

Analysis of the Chinese stock market correlations in high frequency data 中国股市高频数据相关性分析

2011 IEEE International Symposium on IT in Medicine and Education Pub Date : 2011-12-01 DOI: 10.1109/ITIME.2011.6130818

Sun Xuelian

引用次数: 0

Inducible expression of a β-glucuronidase from Penicillium purpurogenum in Pichia pastoris and characterization of the recombinant enzyme 紫红色青霉β-葡萄糖醛酸酶在毕赤酵母中的诱导表达及重组酶的鉴定

2011 IEEE International Symposium on IT in Medicine and Education Pub Date : 2011-12-01 DOI: 10.1109/ITIME.2011.6132193

Xiaoxiao Guo, Chun Li, Xiaoyang Wang

{"title":"Inducible expression of a β-glucuronidase from Penicillium purpurogenum in Pichia pastoris and characterization of the recombinant enzyme","authors":"Xiaoxiao Guo, Chun Li, Xiaoyang Wang","doi":"10.1109/ITIME.2011.6132193","DOIUrl":"https://doi.org/10.1109/ITIME.2011.6132193","url":null,"abstract":"The present study reports the recombinant expression and partial characterization of a novel β-glucuronidase gene from Penicillium purpurogenum Li-3. It is the first time that a β-glucuronidase gene was cloned from Penicillium purpurogenum (pgus, Genbank Accession NO. EU095019). Sequence analysis indicated that pgus has 1815 base pairs, encoding 604 amino acids with the potential molecular weight of 66.7 kDa and 4 potential N-glycosylation sites. The pgus gene was successfully expressed as a functional protein (PGUS-P) in Pichia pastoris GS115. The optimal reaction temperature and pH of PGUS-P were 37.5 °C and pH5.2, respectively. While higher thermal and pH stability were observed in PGUS-P. The Km and Vmax values of PGUS-P for glycyrrhizin ammonium salt (GL) were 0.48 mM and 0.133 mM/min, respectively. The research also showed that the Mg2+, Mn2+ and Na+ have activation effect, while Ag+ and SDS has inhibition effect on the activity of catalyst. In addition, the mature PGUS-P protein exhibited a molecular mass of approximately 90 kDa on SDS-PAGE, which is much higher than its theoretical value. The results revealed that the recombinant PGUS-P may be partly N-glycosylated.","PeriodicalId":170838,"journal":{"name":"2011 IEEE International Symposium on IT in Medicine and Education","volume":"27 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131268638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A web-based system for patient registering and matching in a prospective and observational clinical study 一个基于网络的系统，用于前瞻性和观察性临床研究中的患者登记和匹配

2011 IEEE International Symposium on IT in Medicine and Education Pub Date : 2011-12-01 DOI: 10.1109/ITIME.2011.6130825

H. Cai, J. Xia, F. Yi

{"title":"A web-based system for patient registering and matching in a prospective and observational clinical study","authors":"H. Cai, J. Xia, F. Yi","doi":"10.1109/ITIME.2011.6130825","DOIUrl":"https://doi.org/10.1109/ITIME.2011.6130825","url":null,"abstract":"According to the principle of clinical trial design, treatment and control group should be comparable. In an ongoing prospective observational study to evaluate the effect of CRT (Cardiac resynchronization therapy) for heart failure patients, it is desired that two groups of patients (CRT treatment group and Non-CRT treatment group) were matched into pairs when being registered, and only matched patients were followed up so as to reduce the overall costs. We developed a registering and matching system to meet this requirement. Heart Failure Patients' data were collected from 44 centers by an internet-based system prospectively. 11 potential confounding variables, ranked from 2 to 3 levels, were included in this study. 5 variables were matched absolutely, while 6 others were matched by an “unbalance score”. Patients from each group respectively with the minimum difference were matched within a pre-defined threshold. The matching was done automatically by database system at every night. Unmatched patients who had been registered over 4 weeks were no longer eligible for matching. After 28 months, 478 patients were registered and 206 were matched. After matching, the balance of the covariates between two groups was improved. Alternatives of matching methods are also discussed.","PeriodicalId":170838,"journal":{"name":"2011 IEEE International Symposium on IT in Medicine and Education","volume":"141 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114436693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study of the protein structure analysis and molecular evolution of E-selectin in Homo sapiens 智人e -选择素蛋白结构分析及分子进化研究

2011 IEEE International Symposium on IT in Medicine and Education Pub Date : 2011-12-01 DOI: 10.1109/ITIME.2011.6130749

Qiongshan Wang, Jing Wang, Quhuan Li, Mridula Thapa, Simin Chen

{"title":"Study of the protein structure analysis and molecular evolution of E-selectin in Homo sapiens","authors":"Qiongshan Wang, Jing Wang, Quhuan Li, Mridula Thapa, Simin Chen","doi":"10.1109/ITIME.2011.6130749","DOIUrl":"https://doi.org/10.1109/ITIME.2011.6130749","url":null,"abstract":"E-selectin is a cell adhesion molecule expressed only on endothelial cells activated by cytokines. During inflammation, E-selectin plays an important role in recruiting leukocytes to the site of injury. In humans, E-selectin is encoded by the SELE gene. To better understand the expression and regulation of E-selectin gene, we analyzed the protein structure of E-selectin in human and molecular evolution of its gene in 9 vertebrate animals with bioinformatic softwares and network resources. Results showed that E-selectin is an unstable hydrophilic membrane protein with only one transmembrane domain as well as a signal peptide. The secondary structure is composed of α-helix (11.31%), extended strand (25.74%), and random coil (62.95%). The molecular evolution analysis revealed that the 9 vertebrates were divided into two major branches, one of which includes Bos Taurus, Ovis aries, Odocoileus hemionus, Sus scrofa, Canis Iupus familiaris, Equus caballus and the other is for Homo sapiens, Mus musculus, and Rattus norvegicus. This phylogenetic tree was consistent well with recognized evolutionary relationship among these species. In this research, we investigated the basic protein structure and molecular evolution of E-selectin in Homo sapiens, which will help us to understand how diseases and infection can be controlled in molecular level, and to develop specific drugs based on this knowledge.","PeriodicalId":170838,"journal":{"name":"2011 IEEE International Symposium on IT in Medicine and Education","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114466109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring language laboratory management modes to create a good language learning environment 探索语言实验室管理模式，营造良好的语言学习环境

2011 IEEE International Symposium on IT in Medicine and Education Pub Date : 2011-12-01 DOI: 10.1109/ITIME.2011.6132075

Hao Yuqiu, Zhong Rongjie

引用次数: 2

Reform and practice on self-determination experiment in computer basic teaching 计算机基础教学中自主实验的改革与实践

2011 IEEE International Symposium on IT in Medicine and Education Pub Date : 2011-12-01 DOI: 10.1109/ITIME.2011.6130901

Du Min, Quan Changqing, Jiang Hua

引用次数: 0

A system of portable ECG monitoring based on Bluetooth mobile phone 基于蓝牙手机的便携式心电监护系统

2011 IEEE International Symposium on IT in Medicine and Education Pub Date : 2011-12-01 DOI: 10.1109/ITIME.2011.6132113

Liang Kai, Xu Zhang, Y. Wang, Huang Suibiao, Guangdong Ning, Pang Wangyong, Li Bin, Hongda Chen

引用次数: 33

When students' self regulation of learning in peer group encounters novel knowledge at university 大学生在同伴群体中学习的自我调节遇到新知识

2011 IEEE International Symposium on IT in Medicine and Education Pub Date : 2011-12-01 DOI: 10.1109/ITIME.2011.6132151

Tao Zong

引用次数: 0

Effects of the macroalga Corallina pilulifera on the growth of red tide microalga Prorocentrum micans under laboratory conditions 实验室条件下大藻毛羽珊瑚对红潮微藻micans原心藻生长的影响

2011 IEEE International Symposium on IT in Medicine and Education Pub Date : 2011-12-01 DOI: 10.1109/ITIME.2011.6132085

Renjun Wang, Xue-Xi Tang, J. Sun

{"title":"Effects of the macroalga Corallina pilulifera on the growth of red tide microalga Prorocentrum micans under laboratory conditions","authors":"Renjun Wang, Xue-Xi Tang, J. Sun","doi":"10.1109/ITIME.2011.6132085","DOIUrl":"https://doi.org/10.1109/ITIME.2011.6132085","url":null,"abstract":"Allelopathic effects of several concentrations of fresh tissue and dry powder of three macroalgae, Grateloupia turuturu, Corallina pilulifera and Gelidium amansii, on the red tide microalga Prorocentrum micans were evaluated in microcosms. Preliminary studies on the algicidal effects of one aqueous and four organic solvent extracts from C. pilulifera on the P. micans were carried out to confirm the existence of allelochemicals in the tissues of the macroalga. The results of the microcosm assay showed that the growth of P. micans was strongly inhibited by using fresh tissues and dry powder of the three macroalgae, the inhibitory effect of C. pilulifera is the best. Both aqueous and methanol extracts of C. pilulifera had strong growth inhibitory effects on P. micans, while the other three organic solvent extracts (acetone, ether and chloroform) had no apparent effect on its growth, this suggested that the allelochemicals from C. pilulifera had relatively high polarities. The dry powder of C. pilulifera was extracted with methanol, and the methanol extracts were partitioned to petroleum ether phase, ethyl acetate phase, butanol phase and distilled phase by liquid-liquid fractionation. The bioassays of the activity of every fraction were carried out on P. micans, indicated that petroleum ether phase and ethyl acetate phase had strong algicidal effect on P. micans.","PeriodicalId":170838,"journal":{"name":"2011 IEEE International Symposium on IT in Medicine and Education","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121986563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0