Journal of Perinatology最新文献_第6页

Stochastic vibration and early weight growth in opioid-exposed newborns: a randomized trial. 阿片类药物暴露新生儿的随机振动和早期体重增长：一项随机试验。

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-08-24 DOI: 10.1038/s41372-026-02862-z

Elisabeth Bloch-Salisbury, Nicolas Rodriguez, Tory Bruch, Lauren McKenna, Matthew Derbin, Dane Netherton, Toby Yanowitz, Sue R Beers, Mark Vining, James D Wilson

{"title":"Stochastic vibration and early weight growth in opioid-exposed newborns: a randomized trial.","authors":"Elisabeth Bloch-Salisbury, Nicolas Rodriguez, Tory Bruch, Lauren McKenna, Matthew Derbin, Dane Netherton, Toby Yanowitz, Sue R Beers, Mark Vining, James D Wilson","doi":"10.1038/s41372-026-02862-z","DOIUrl":"https://doi.org/10.1038/s41372-026-02862-z","url":null,"abstract":"Objective: To test whether stochastic vibrotactile stimulation (SVS) improved early weight trajectories in hospitalized term newborns with prenatal opioid exposure.Study design: This prospective, two-site randomized controlled trial compared days to lowest weight following birthweight [Nadir], maximal percent weight loss from birthweight [MaxLoss], days to return to birthweight [RtB], and weekly percent weight change from birth through the first month of life between infants who received treatment as usual (TAU) and infants who received SVS throughout hospitalization.Results: Among 181 term newborns [mean gestational age 39.0 ± 1.2weeks), no differences were observed between TAU (n = 87) and SVS (n = 94) for Nadir, MaxLoss, or RtB. Among symptomatic infants treated with morphine, mean weight gain at four weeks was significantly greater for SVS (29.88 ± 1.02%) than TAU (18.15 ± 7.31%; p < 0.05).Conclusions: Among morphine-treated infants, the SVS cohort had greater early weight growth than the TAU cohort. Weight growth via SVS has implications for reduced morbidities and improved developmental outcomes in at-risk opioid-exposed newborns.Clinical trial registry: June 6, 2016, clinicaltrials.gov NCT02801331 ( https://clinicaltrials.gov/study/NCT02801331 ).","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148813341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Consensus-based eligibility criteria and component definitions for neonatal and infant enhanced recovery pathway: a multidisciplinary delphi study. 基于共识的新生儿和婴儿增强恢复途径的资格标准和成分定义：一项多学科德尔菲研究。

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-08-24 DOI: 10.1038/s41372-026-02881-w

Johanna M Borst, Mehul V Raval, Mallory N Perez, Gustave H Falciglia, Nicholas E Burjek, Jane L Holl, Willemijn L A Schäfer

{"title":"Consensus-based eligibility criteria and component definitions for neonatal and infant enhanced recovery pathway: a multidisciplinary delphi study.","authors":"Johanna M Borst, Mehul V Raval, Mallory N Perez, Gustave H Falciglia, Nicholas E Burjek, Jane L Holl, Willemijn L A Schäfer","doi":"10.1038/s41372-026-02881-w","DOIUrl":"https://doi.org/10.1038/s41372-026-02881-w","url":null,"abstract":"Objective: The 2020 Enhanced Recovery After Surgery (ERAS®) guidelines for neonatal intestinal surgery have not been widely implemented due to unclear eligibility criteria and poorly defined components. We sought to establish consensus-based eligibility criteria and definitions for a revised enhanced recovery pathway (ERP).Study design: We conducted two modified Delphi processes to establish eligibility criteria and define the components by engaging stakeholders including surgeons, anesthesiologists, neonatologists, nurses, dietitians, quality improvement specialists, and parents/caregivers at six pediatric hospitals. Eligibility criteria were established through two survey rounds; components were defined through two survey rounds and one focus group.Results: Forty-five stakeholders participated (82% response). Consensus supported inclusion of infants born ≥32 weeks' gestation or ≥1.5 kg undergoing elective/semi-urgent gastrointestinal surgery and defined 19 components, with 10 initially accepted and 9 revised.Conclusions: The consensus-based Delphi process established eligibility and defined the components to facilitate implementation and adoption of an ERP for neonates and infants undergoing gastrointestinal surgery.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148813343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk assessment of early-onset sepsis in extremely preterm infants: implications for antibiotic stewardship. 极早产儿早发性脓毒症的风险评估：抗生素管理的意义。

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-08-21 DOI: 10.1038/s41372-026-02879-4

Alessandra Guiterrez, Imran Mir, Katherine Stumpf, Leslee M Roberts, Natasha W Hanners, L Steven Brown, Julide Sisman

{"title":"Risk assessment of early-onset sepsis in extremely preterm infants: implications for antibiotic stewardship.","authors":"Alessandra Guiterrez, Imran Mir, Katherine Stumpf, Leslee M Roberts, Natasha W Hanners, L Steven Brown, Julide Sisman","doi":"10.1038/s41372-026-02879-4","DOIUrl":"https://doi.org/10.1038/s41372-026-02879-4","url":null,"abstract":"Objective: To identify risk factors for early-onset sepsis (EOS) in extremely preterm infants.Study design: This retrospective study included 554 infants at 22-296/7 weeks' gestation at Parkland Hospital Dallas, Texas, from 2018 to 2023. Proven EOS was defined by positive blood culture within 72 hours after birth; suspected EOS by ≥5 days of antibiotics despite negative cultures. Remaining infants served as controls. Maternal, neonatal, delivery, and placental characteristics were compared. Low EOS risk was defined as cesarean delivery without labor, rupture of membranes (ROM) at delivery, and no chorioamnionitis.Results: Prelabor preterm ROM and acute chorioamnionitis on placental pathology were more common among the infants with EOS than those with suspected sepsis and controls (P = 0.02; OR 5.5, 95% CI 1.43-21, P = 0.01, respectively). None of the infants with proven EOS were classified as low risk.Conclusion: Risk assessment for EOS should be promoted to enhance antibiotic stewardship.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148794682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring hope in parents of infants discharged from the neonatal intensive care unit: a cross-sectional study. 探索新生儿重症监护病房出院婴儿父母的希望：一项横断面研究。

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-08-21 DOI: 10.1038/s41372-026-02875-8

Christine Arnold, Ruth Birrer, Katja Odermatt, Benedikt Bubl, Marta Busso, Sophie Jaisli, Stephanie Vanessa Schmid, André Kidszun

{"title":"Exploring hope in parents of infants discharged from the neonatal intensive care unit: a cross-sectional study.","authors":"Christine Arnold, Ruth Birrer, Katja Odermatt, Benedikt Bubl, Marta Busso, Sophie Jaisli, Stephanie Vanessa Schmid, André Kidszun","doi":"10.1038/s41372-026-02875-8","DOIUrl":"https://doi.org/10.1038/s41372-026-02875-8","url":null,"abstract":"Objective: This study aimed to explore levels of hope among parents of infants at the time of NICU discharge and to identify associations with parental, infant, and psychological factors.Study design: In a single-center cross-sectional study (May 2023 to November 2024), parents of infants hospitalized for ≥ 24 h in a tertiary NICU completed the Herth-Hope-Index (HHI-D), the Optimism-Pessimism Short Scale (SOP-2), and the Patient Health Questionnaire-4 (PHQ-4) at discharge. Multivariable linear regression examined associations between hope and parental or infant characteristics.Results: In 138 mothers and 89 fathers, median HHI-D scores were similar (44.0). Most had high levels of hope (HHI-D > 36; 92%). Sixty-two percent were optimistic (SOP-2 ≥ 6) and 9% reported moderate to severe depressive symptoms (PHQ-4 ≥ 6). Higher hope was associated with greater optimism and fewer depressive symptoms in both mothers and fathers.Conclusion: Identifying and supporting parents with low optimism or depressive symptoms may help maintain hope during transition home.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148794564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Weighted and unweighted comorbidity burden for predicting three-year neurodevelopment in extremely preterm infants: A nationwide cohort study. 预测极早产儿3岁神经发育的加权和未加权共病负担：一项全国性队列研究。

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-08-21 DOI: 10.1038/s41372-026-02873-w

Shuji Ishida, Hidehiko Nakanishi, Izumi Iitsuka, Moe Matsuura, Yoshie Oosaki, Maki Iwai, Rika Sekiya, Kohei Kawada, Yukako Kosaka, Ayano Yamaguchi, Mari Ooka

{"title":"Weighted and unweighted comorbidity burden for predicting three-year neurodevelopment in extremely preterm infants: A nationwide cohort study.","authors":"Shuji Ishida, Hidehiko Nakanishi, Izumi Iitsuka, Moe Matsuura, Yoshie Oosaki, Maki Iwai, Rika Sekiya, Kohei Kawada, Yukako Kosaka, Ayano Yamaguchi, Mari Ooka","doi":"10.1038/s41372-026-02873-w","DOIUrl":"https://doi.org/10.1038/s41372-026-02873-w","url":null,"abstract":"Objective: To compare the prognostic utility of unweighted morbidity counts and weighted morbidity scores for predicting neurodevelopmental outcomes at 3 years in extremely preterm infants.Study design: This retrospective cohort study used data from the Neonatal Research Network of Japan and included infants born at <28 weeks' gestation. Neurodevelopment at 3 years was assessed using developmental quotient and cerebral palsy. Cumulative morbidity burden was quantified using unweighted morbidity counts and weighted morbidity scores derived from log-odds ratios for severe impairment. Inverse probability weighting addressed incomplete follow-up.Results: Both unweighted morbidity counts and weighted morbidity scores were significantly associated with adverse neurodevelopmental outcomes. Unweighted morbidity counts demonstrated higher sensitivity for identifying any adverse outcome, whereas weighted morbidity scores showed high specificity (0.94) for severe impairment.Conclusion: Unweighted morbidity counts and weighted morbidity scores provide complementary prognostic information and may improve risk stratification, follow-up prioritization, and family counseling for extremely preterm infants.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148794634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Engaging families to improve high-risk infant follow-up participation: a mixed methods study. 家庭参与提高高危婴儿随访参与：一项混合方法研究。

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-08-21 DOI: 10.1038/s41372-026-02885-6

Christine Sugimoto, Melissa Murphy, Salathiel Kendrick-Allwood, Valerie Croft, Nathalie Maitre

{"title":"Engaging families to improve high-risk infant follow-up participation: a mixed methods study.","authors":"Christine Sugimoto, Melissa Murphy, Salathiel Kendrick-Allwood, Valerie Croft, Nathalie Maitre","doi":"10.1038/s41372-026-02885-6","DOIUrl":"https://doi.org/10.1038/s41372-026-02885-6","url":null,"abstract":"Objective: Identify factors that impact attendance at a regional high-risk infant follow-up (HRIF) program and explore caregiver perceived barriers and facilitators to participation.Study design: A retrospective study identified factors associated with first visit non-attendance amongst infants referred to HRIF. Results guided recruitment for a mixed methods needs assessment including surveys and structured interviews to understand caregiver perspectives through inductive qualitative thematic analysis.Results: Compared to infants who attended an initial HRIF visit, infants who did not attend had higher mean birthweight, public or no insurance, and maternal nativity outside the US. Qualitative prospective analyses revealed barriers and facilitators to HRIF program attendance were logistics, schedule, customer service, support for parental needs, knowledge, and attitude and motivation.Conclusion: Interventions to improve HRIF program participation should engage families at high-risk of non-attendance from the NICU stay onward and should focus on education, social needs, and customer service.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148794581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diaphragm ultrasound and lung aeration in small-for-gestational-age versus appropriate-for-gestational-age newborns: a cross-sectional study. 横断面研究：小胎龄与适当胎龄新生儿的膈超声和肺通气

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-08-21 DOI: 10.1038/s41372-026-02883-8

Ingrid Kelly Silva de Macedo, Mayson Laercio de Araujo Sousa, Bárbara Bernardo Rinaldo da Silva Figueirêdo, Paulo André Freire Magalhães

{"title":"Diaphragm ultrasound and lung aeration in small-for-gestational-age versus appropriate-for-gestational-age newborns: a cross-sectional study.","authors":"Ingrid Kelly Silva de Macedo, Mayson Laercio de Araujo Sousa, Bárbara Bernardo Rinaldo da Silva Figueirêdo, Paulo André Freire Magalhães","doi":"10.1038/s41372-026-02883-8","DOIUrl":"https://doi.org/10.1038/s41372-026-02883-8","url":null,"abstract":"Objective: To compare diaphragm ultrasound findings and lung aeration between SGA and AGA newborns.Methods: In this cross-sectional study, clinically stable term SGA and AGA newborns underwent diaphragm and lung ultrasound. Diaphragm parameters and 6-region lung ultrasound score (LUS) were assessed, with thickness and excursion normalized by birth weight.Results: Fifty-four newborns were included (27 SGA and 27 AGA). SGA newborns had lower absolute inspiratory and expiratory diaphragmatic thicknesses; however, these between-group differences were no longer significant after normalization by birth weight. Regression analyses adjusting for body weight continued to demonstrate an association between SGA status and diaphragmatic thickness. No significant differences were observed in diaphragmatic functional indices or pulmonary aeration.Conclusions: SGA newborns had lower absolute diaphragmatic thickness than AGA newborns, while diaphragmatic function and pulmonary aeration were preserved. Differences in thickness were influenced by body size but were not fully explained by birth weight.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148794562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Local anesthetic techniques for analgesia in neonatal circumcision: a network meta-analysis. 新生儿包皮环切术的局部麻醉镇痛技术：网络荟萃分析。

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-08-20 DOI: 10.1038/s41372-026-02878-5

Gabriel Lemos González, Gustavo Roberto Minetto Wegner, Bruno Francisco Minetto Wegner, Iaci Luisa Lopes de Mattos, Catherine Maria Fasano Werner, Fani Nhuch, Vitor Alves Felippe, Tatiana Souza Nascimento

{"title":"Local anesthetic techniques for analgesia in neonatal circumcision: a network meta-analysis.","authors":"Gabriel Lemos González, Gustavo Roberto Minetto Wegner, Bruno Francisco Minetto Wegner, Iaci Luisa Lopes de Mattos, Catherine Maria Fasano Werner, Fani Nhuch, Vitor Alves Felippe, Tatiana Souza Nascimento","doi":"10.1038/s41372-026-02878-5","DOIUrl":"https://doi.org/10.1038/s41372-026-02878-5","url":null,"abstract":"Objective: Neonatal circumcision is often performed without adequate analgesia despite significant harm related to acute pain. We compared local anesthetic techniques using network meta-analysis based on intraoperative physiological responses.Study design: Frequentist network meta-analysis of randomized controlled trials comparing nerve blocks (dorsal penile nerve block, DPNB; ring block, RB), topical anesthetics (eutectic mixture of local anesthetics, EMLA; topical lidocaine, TL), combination techniques, and control.Outcomes: intraoperative heart rate, oxygen saturation, their variation, respiratory rate, and hematoma. Risk of bias and certainty of evidence were assessed.Results: Eighteen trials (1 035 neonates) were included. Nerve blocks reduced pain-related responses versus control and TL. DPNB outperformed EMLA, with increased hematoma risk. Meta-regression suggests smaller effect size in recent studies.Conclusions: Evidence supports local anesthetic techniques for neonatal circumcision, with nerve blocks providing greater benefit than topical anesthetics. However, given the small sample sizes and low certainty of evidence, higher-quality trials are needed.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148794535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between ambient noise and physiologic changes in neonates with single-ventricle physiology after the Norwood procedure. 环境噪声与诺伍德手术后单心室新生儿生理变化之间的关系。

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-08-19 DOI: 10.1038/s41372-026-02876-7

Molly E McGetrick, Sulimon Sattari, Chetna K Pande, Justin J Elhoff, Fabio Savorgnan

{"title":"Association between ambient noise and physiologic changes in neonates with single-ventricle physiology after the Norwood procedure.","authors":"Molly E McGetrick, Sulimon Sattari, Chetna K Pande, Justin J Elhoff, Fabio Savorgnan","doi":"10.1038/s41372-026-02876-7","DOIUrl":"https://doi.org/10.1038/s41372-026-02876-7","url":null,"abstract":"Objective: To characterize ambient noise and acute physiologic changes in neonates after Stage 1 Norwood palliation.Study design: We retrospectively analyzed synchronized sound and physiologic data from 12 neonates >36 weeks' gestation with a Sano or modified Blalock-Taussig-Thomas shunt during the first 48 postoperative hs.Result: Among 1,014,403 audio observations, 25th percentile ambient sound levels were 69.05, 70.35, and 70.75 dBA during postoperative hs 0-12, 12-24, and 24-48, respectively, exceeding published recommendations. Overall, 3936 noisy events were identified. Time in the noisy range increased from 47 min during hs 0-12 to 266 min during hs 24-48. Noisy events were associated with small heart rate increases, somatic near-infrared spectroscopy decreases, and epoch-dependent changes in mean arterial blood pressure.Conclusion: Noisy events were common after Norwood palliation and associated with small physiologic changes consistent with altered systemic perfusion. Prospective studies should evaluate whether noise reduction improves physiologic stability.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148794557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Social & economic neighborhood opportunity as predictors of neurodevelopmental outcomes in high-risk infants. 社会和经济邻里机会作为高危婴儿神经发育结局的预测因素。

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-08-19 DOI: 10.1038/s41372-026-02882-9

Marcus P Mosley, Wendi Gu, Sylvan Ryder, Annette Zygmunt, Andrew S Geneslaw, Sandhya S Brachio

{"title":"Social & economic neighborhood opportunity as predictors of neurodevelopmental outcomes in high-risk infants.","authors":"Marcus P Mosley, Wendi Gu, Sylvan Ryder, Annette Zygmunt, Andrew S Geneslaw, Sandhya S Brachio","doi":"10.1038/s41372-026-02882-9","DOIUrl":"https://doi.org/10.1038/s41372-026-02882-9","url":null,"abstract":"Objective: To assess whether neighborhood opportunity is associated with language, cognitive, and motor outcomes among NICU graduates.Study design: We conducted a retrospective cohort study of 103 infants followed in a NICU follow-up clinic in New York City (2021-2022). Neighborhood opportunity was measured using the Child Opportunity Index (COI) 3.0. Development was assessed using the Bayley Scales of Infant and Toddler Development, 4th Edition (BSID-IV) at 17.5-24 months corrected age. Multivariable linear regression models adjusted for clinical and sociodemographic factors.Results: Infants residing in lower-opportunity neighborhoods had lower BSID-IV scores. The Social and Economic COI domain was the only domain significantly associated with outcomes and was associated with higher language (β = 7.10, p = 0.031) and motor (β = 6.48, p = 0.012) scores.Conclusion: Lower neighborhood opportunity, particularly within the social and economic domain, is associated with adverse neurodevelopmental outcomes among NICU graduates.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148794717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0