Journal of Perinatology最新文献_第6页

Development of a checklist for evaluation of shared decision-making in consultation for extremely preterm delivery. 为评估极度早产咨询中的共同决策制定一份核对表。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2024-10-22 DOI: 10.1038/s41372-024-02136-6

Michael Guindon, Dalia M Feltman, Carrie Litke-Wager, Elizabeth Okonek, Kaitlyn T Mullin, Uchenna E Anani, Peter D Murray Ii, Christopher Mattson, Jeanne Krick

{"title":"Development of a checklist for evaluation of shared decision-making in consultation for extremely preterm delivery.","authors":"Michael Guindon, Dalia M Feltman, Carrie Litke-Wager, Elizabeth Okonek, Kaitlyn T Mullin, Uchenna E Anani, Peter D Murray Ii, Christopher Mattson, Jeanne Krick","doi":"10.1038/s41372-024-02136-6","DOIUrl":"https://doi.org/10.1038/s41372-024-02136-6","url":null,"abstract":"Objective: Shared decision-making (SDM) between parents facing extremely preterm delivery and the medical team is recommended to develop the best course of action for neonatal care. We aimed to describe the creation and testing of a literature-based checklist to assess SDM practices for consultation with parents facing extremely preterm delivery.Study design: The checklist of SDM counseling behaviors was created after literature review and with expert consensus. Mock consultations with a standardized patient facing extremely preterm delivery were performed, video-recorded, and scored using the checklist. Intraclass correlation coefficients and Cronbach's alpha were calculated.Result: The checklist was moderately reliable for all scorers in aggregate. Differences existed between subcategories within classes of scorer, and between scorer classes. Agreement was moderate between expert scorers, but poor between novice scorers. Internal consistency of the checklist was excellent (Cronbach's alpha = 0.93).Conclusion: This novel checklist for evaluating SDM shows promise for use in future research, training, and clinical settings.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142502486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Culture negative sepsis: a national survey of variations in clinical practice 培养阴性败血症：全国临床实践差异调查。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2024-10-18 DOI: 10.1038/s41372-024-02140-w

Jina Park, Theodore De Beritto, Angela Douglas, Barbara Brumbach, Kenneth Andrew Alexander, Joseph R. Hageman

引用次数: 0

Somatic growth outcomes in response to an individualized neonatal sodium supplementation protocol. 个体化新生儿钠补充方案的体格生长结果。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2024-10-17 DOI: 10.1038/s41372-024-02141-9

Elliot J Stalter, Silvia L Verhofste, John M Dagle, Emily J Steinbach, Patrick Ten Eyck, Linder Wendt, Jeffrey L Segar, Lyndsay A Harshman

{"title":"Somatic growth outcomes in response to an individualized neonatal sodium supplementation protocol.","authors":"Elliot J Stalter, Silvia L Verhofste, John M Dagle, Emily J Steinbach, Patrick Ten Eyck, Linder Wendt, Jeffrey L Segar, Lyndsay A Harshman","doi":"10.1038/s41372-024-02141-9","DOIUrl":"10.1038/s41372-024-02141-9","url":null,"abstract":"Objective: Evaluate the impact of a sodium (Na) supplementation protocol based upon urine Na concentration on growth parameters and morbidities.Study design: Retrospective cohort study of infants 260/7-336/7 weeks gestational age (GA) cared for before (2012-15, n = 310) and after (2016-20, n = 382) implementation of the protocol. Within- and between-group changes over time were assessed using repeated measures generalized linear models.Results: For infants 260/7-296/7 weeks GA, utilization of the protocol was associated with increased mean body weight z-score at 8-weeks postnatal age, increased mean head circumference z-score at 16-weeks postnatal age, and decreased time on mechanical ventilation (all p < 0.02). No impact on growth was identified for infants 30-336/7 weeks GA. Incidences of hypertension, hypernatremia, bronchopulmonary dysplasia, necrotizing enterocolitis, and culture positive sepsis were unaffected by the protocol.Conclusion: Protocolized Na supplementation is associated with improved growth and reduced time on invasive mechanical ventilation in extremely preterm infants without increasing incidence of morbidities.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early drug treatment in preterm patients with large patent ductus arteriosus at 28 weeks or less gestational age: systematic review and meta-analysis. 胎龄 28 周或不足 28 周的大动脉导管未闭早产儿的早期药物治疗：系统综述和荟萃分析。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2024-10-17 DOI: 10.1038/s41372-024-02154-4

Gabriel Erzinger, Gokul Rajith, Matheus H Torres, Mateus de Miranda Gauza, Zeeshan Mansuri, Silvia M Cardoso

{"title":"Early drug treatment in preterm patients with large patent ductus arteriosus at 28 weeks or less gestational age: systematic review and meta-analysis.","authors":"Gabriel Erzinger, Gokul Rajith, Matheus H Torres, Mateus de Miranda Gauza, Zeeshan Mansuri, Silvia M Cardoso","doi":"10.1038/s41372-024-02154-4","DOIUrl":"https://doi.org/10.1038/s41372-024-02154-4","url":null,"abstract":"Objective: Compare the use of nonsteroidal anti-inflammatory drugs (NSAIDs) with placebo/expectant management in preterm infants at 28 weeks or less gestational age with a large Patent Ductus (PDA).Study design: A meta-analysis of RCTs following PRISMA guidelines comparing the use of NSAIDs with placebo/expectant management in extremely preterm infants with a large PDA.Results: There were no significant differences between the NSAIDs and placebo/expectant groups for all-cause mortality (RR 1.27; 95% CI 0.97-1.65; p = 0.081). However, the ibuprofen subgroup showed a significant difference in all-cause mortality (RR 1.36; 95% CI 1.03-1.80; p = 0.03) favoring the placebo/expectant group.Conclusion: In extremely preterm infants with a large PDA on ultrasound, early treatment with NSAIDs provides no additional clinical benefit compared to placebo/expectant treatment. Ibuprofen was associated with an increased risk ratio for all-cause mortality in the subgroup analysis.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Implementation of a novel bubble continuous positive airway pressure system with a blender in preterm infants in a low resource setting. 在资源匮乏的环境中，为早产儿实施带搅拌器的新型气泡持续气道正压系统。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2024-10-15 DOI: 10.1038/s41372-024-02153-5

Emily Ahn, Aisa Shayo, Matei Mselle, Anna Sechu, Jeffrey Perlman

{"title":"Implementation of a novel bubble continuous positive airway pressure system with a blender in preterm infants in a low resource setting.","authors":"Emily Ahn, Aisa Shayo, Matei Mselle, Anna Sechu, Jeffrey Perlman","doi":"10.1038/s41372-024-02153-5","DOIUrl":"https://doi.org/10.1038/s41372-024-02153-5","url":null,"abstract":"Objective: To determine if a novel CPAP system is associated with physiologic improvement in premature infants in a low resource setting and if the introduction of blended oxygen would reduce FiO2.Study design: Feasibility study of infants ≤2000 g or ≤32 weeks gestational age with early respiratory distress who were placed on Vayu CPAP with continuous pulse oximetry. Physiologic parameters were recorded prior to initiation and through the first 24 h.Results: Seventy-six infants of birthweight 1360 ± 324 g and gestational age 31.2 ± 2.5 weeks were included. Compared to baseline, heart rate, respiratory rate, FiO2, and Silverman Anderson score significantly decreased while oxygen saturations significantly increased at one hour with persistence through 24 h.Conclusion: Utilization of Vayu CPAP in premature infants with respiratory distress was associated with immediate improvement in physiologic parameters. Use of blended oxygen coupled with pulse oximetry facilitates reduction in delivered oxygen.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Navigating parental disagreement: ethical analysis and a proposed approach. 引导父母的分歧：伦理分析和建议的方法。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2024-10-15 DOI: 10.1038/s41372-024-02152-6

Alice C Baker, Mark R Mercurio

{"title":"Navigating parental disagreement: ethical analysis and a proposed approach.","authors":"Alice C Baker, Mark R Mercurio","doi":"10.1038/s41372-024-02152-6","DOIUrl":"https://doi.org/10.1038/s41372-024-02152-6","url":null,"abstract":"Shared decision-making in pediatrics can be problematic when disagreements arise. The impermissible-permissible-obligatory (I-P-O) framework helps define the limits of parental authority when clinicians disagree with parents. There is little guidance in the literature, however, on making critical clinical decisions when parents disagree with each other. We use a clinical case involving parental disagreement over resuscitation at borderline gestational age to provide context for an analysis of several potential approaches based on established ethical principles of pediatric decision-making. We identify four potential options for delivery room care: (1) Defer to the pregnant parent; (2) withhold resuscitation unless both parents agree to it; (3) attempt resuscitation if either parent requests it; (4) decide about resuscitation using a framework of advisability. The merits and flaws of each approach are discussed. We propose an expansion of the I-P-O framework that uses consideration of clinical details, an assessment of the patient's best interest, and parental values to determine clinical advisability to guide decision-making in the setting of parental discordance.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prediction of site-specific pharmacologic therapy among newborns with neonatal opioid withdrawal syndrome. 对患有新生儿阿片类药物戒断综合征的新生儿进行特定部位药物治疗的预测。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2024-10-15 DOI: 10.1038/s41372-024-02144-6

Mara G Coyle, Songthip T Ounpraseuth, Barry Lester, Lynne M Dansereau, Zhuopei Hu, Abbot Laptook

{"title":"Prediction of site-specific pharmacologic therapy among newborns with neonatal opioid withdrawal syndrome.","authors":"Mara G Coyle, Songthip T Ounpraseuth, Barry Lester, Lynne M Dansereau, Zhuopei Hu, Abbot Laptook","doi":"10.1038/s41372-024-02144-6","DOIUrl":"https://doi.org/10.1038/s41372-024-02144-6","url":null,"abstract":"Objective: To predict pharmacotherapy for NOWS based on factors available shortly after birth.Study design: A multi-center, retrospective study of 1377 opioid exposed newborns between 2016 and 2017 dichotomized based on pharmacologic treatment (N = 665 treated, N = 712 not treated) was conducted. A multilevel mixed-effect logistic regression model that considered cluster effect from sites determined significant maternal and newborn factors associated with pharmacotherapy, which were combined in a nomogram to predict probability of treatment for infants at each participating site.Results: Factors predictive of treatment were: no breastmilk (1.76, 1.30-2.39; p < 0.001), male sex (1.39, 1.05-1.83; p = 0.021), polysubstance exposure (1.53, 1.15-2.06; p = 0.004), inadequate prenatal care (1.51, 1.07-2.13; p < 0.018) and Methadone (6.08, 4.03-9.27; p < 0.001) or Buprenorphine (1.86, 1.29-2.69; p < 0.001). A site-specific nomogram provided the probability of treatment for individual newborns.Conclusion: Six factors available shortly after birth can be combined to predict site-specific use of medication for NOWS. If confirmed, the nomogram may identify at-risk newborns.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The number of blood transfusions received and the incidence and severity of chronic lung disease among NICU patients born >31 weeks gestation. 妊娠大于 31 周的新生儿重症监护室患者接受输血的次数以及慢性肺病的发病率和严重程度。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2024-10-15 DOI: 10.1038/s41372-024-02135-7

Timothy M Bahr, Robin K Ohls, Erick Henry, Patricia Davenport, Sarah J Ilstrup, Walter E Kelley, Bradley A Yoder, Martha C Sola-Visner, Robert D Christensen

{"title":"The number of blood transfusions received and the incidence and severity of chronic lung disease among NICU patients born >31 weeks gestation.","authors":"Timothy M Bahr, Robin K Ohls, Erick Henry, Patricia Davenport, Sarah J Ilstrup, Walter E Kelley, Bradley A Yoder, Martha C Sola-Visner, Robert D Christensen","doi":"10.1038/s41372-024-02135-7","DOIUrl":"https://doi.org/10.1038/s41372-024-02135-7","url":null,"abstract":"Objective: We previously reported the possible pathogenic role, among infants born ≤29 weeks, of transfusions in bronchopulmonary dysplasia. The present study examined this association in infants born >31 weeks.Study design: Analysis of red blood cell (RBC) and platelet transfusions in five NICUs to infants born >31 weeks, and chronic neonatal lung disease (CNLD) at six-weeks of age.Results: Seven-hundred-fifty-one infants born >31 weeks were still in the NICU when six-weeks of age. CNLD was identified in 397 (53%). RBC and platelet transfusions were independently associated with CNLD after controlling for potential confounders. For every transfusion, the adjusted odds of developing CNLD increased by a factor of 1.64 (95% CI, 1.38-2.02; p < 0.001).Conclusions: Among NICU patients born >31 weeks, transfusions received by six weeks are associated with CNLD incidence and severity. Though we controlled for known confounding variables in our regression models, severity of illness is an important confounder that limits our conclusions.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of standard assessment of post-hemorrhagic ventricular dilation to improve collaboration with referring centers. 采用出血后心室扩张的标准评估方法，加强与转诊中心的合作。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2024-10-15 DOI: 10.1038/s41372-024-02142-8

Alicia Sprecher, Samuel Adams, Erwin Cabacungan, Katherine Carlton, Tejaswini Deshmukh, Andrew Foy, Michael Hokenson, Mohit Maheshwari, Daniel Murphy, Mario Powell, Kimberly Seeger Langlais, Susan Cohen

引用次数: 0

A pilot study of a virtual reality-based simulation platform for Neonatal Resuscitation Program training. 新生儿复苏计划培训虚拟现实模拟平台试点研究。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2024-10-14 DOI: 10.1038/s41372-024-02145-5

GiaKhanh Trinh, Ryan M McAdams

{"title":"A pilot study of a virtual reality-based simulation platform for Neonatal Resuscitation Program training.","authors":"GiaKhanh Trinh, Ryan M McAdams","doi":"10.1038/s41372-024-02145-5","DOIUrl":"https://doi.org/10.1038/s41372-024-02145-5","url":null,"abstract":"Objective: This pilot implementation study introduces a novel, neonatal-specific virtual reality (VR) simulation platform for resuscitation training and assesses its initial feasibility and reception in a neonatal intensive care unit setting.Study design: We developed a custom VR model simulating a resuscitation scenario for a 30-week neonate. Neonatal providers completed individualized training sessions and post-training surveys.Results: Thirty-eight neonatal providers participated in the study. The VR platform was well-received, with 97% willing to use it again and 95% recommending it. Most participants (70.3%) found VR more realistic than traditional methods, with an average usefulness rating of 4.5/5. However, 40.5% reported adverse effects like eye strain and motion sickness. Feedback led to three significant VR platform upgrades.Conclusion: This study demonstrates strong enthusiasm for VR among neonatal providers. While promising, further research with larger samples and comparisons to traditional methods is needed to fully evaluate VR's effectiveness in neonatal resuscitation training.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0