Journal of Perinatology最新文献_第6页

Feasibility of virtual reality-based simulation for neonatal resuscitation training: a pilot study at an international site. 基于虚拟现实的新生儿复苏训练模拟的可行性：在一个国际站点的试点研究。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-08-20 DOI: 10.1038/s41372-025-02382-2

GiaKhanh Trinh, Binh Ho T T, Jens C Eickhoff, Ryan M McAdams

{"title":"Feasibility of virtual reality-based simulation for neonatal resuscitation training: a pilot study at an international site.","authors":"GiaKhanh Trinh, Binh Ho T T, Jens C Eickhoff, Ryan M McAdams","doi":"10.1038/s41372-025-02382-2","DOIUrl":"https://doi.org/10.1038/s41372-025-02382-2","url":null,"abstract":"Background: Virtual reality (VR) offers immersive training experiences that can address limitations of traditional neonatal resuscitation training. Building on prior U.S.-based research, we evaluated the feasibility of deploying a VR-based neonatal resuscitation model in an international setting.Methods: Healthcare providers at Ho Chi Minh City Children's Hospital in Vietnam participated in a single-arm feasibility study using VR-based training. Sessions employed a team-based approach with physicians, nurses, and allied health professionals and included knowledge review, platform orientation, and a simulated resuscitation scenario based on the Neonatal Resuscitation Program. The simulation was delivered in English with real-time Vietnamese translation. Participants completed post-training surveys assessing satisfaction, realism, and challenges.Results: Among 28 participants, 100% recommended VR training; 86% found it more realistic than traditional methods. The mean usefulness score was 4.3/5. Challenges included language barriers and technical issues.Conclusions: VR-based neonatal resuscitation training is feasible and well-received at Ho Chi Minh City Children's Hospital, Vietnam.Clinical trial registration: Not applicable.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of oral dextrose gel for neonates at risk of hypoglycemia: A systematic review, meta-analysis, and GRADE assessment of randomized controlled trials 口服葡萄糖凝胶治疗低血糖风险新生儿的有效性：随机对照试验的系统回顾、荟萃分析和GRADE评估

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-08-20 DOI: 10.1038/s41372-025-02387-x

Gowardhan Sivakumar, Periyasamy Kuppusamy, Lakshmi Prasanna P, Abha Mishra, Sasidharan Sivakumar

{"title":"Effectiveness of oral dextrose gel for neonates at risk of hypoglycemia: A systematic review, meta-analysis, and GRADE assessment of randomized controlled trials","authors":"Gowardhan Sivakumar, Periyasamy Kuppusamy, Lakshmi Prasanna P, Abha Mishra, Sasidharan Sivakumar","doi":"10.1038/s41372-025-02387-x","DOIUrl":"10.1038/s41372-025-02387-x","url":null,"abstract":"Neonatal hypoglycemia is the most common metabolic disorder in newborns and can lead to neurological damage if untreated. While intravenous dextrose is the standard treatment, it is invasive. Oral 40% dextrose gel (0.5 ml/kg) offers a non-invasive alternative. A systematic review of five randomized controlled trials (RCTs), involving 2,742 neonates (1,326 received dextrose gel; 1,416 received placebo), assessed its effectiveness in reducing NICU admissions in neonates with blood glucose < 2.6 mmol/L. Although the overall meta-analysis showed a non-significant reduction in NICU admissions (risk ratio 0.68; 95% CI: 0.33–1.38; p = 0.28), a sensitivity analysis excluding one outlier study improved consistency (I² = 19%) and revealed a statistically significant reduction (risk ratio 0.52; 95% CI: 0.31–0.90; p = 0.02). These findings suggest that oral dextrose gel may reduce NICU admissions in neonates with hypoglycemia, but further large-scale studies are required to confirm its clinical effectiveness.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":"45 10","pages":"1335-1344"},"PeriodicalIF":2.4,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inequities in prenatal neonatology consultation in high-mortality neonatal populations 高死亡率新生儿人群产前新生儿咨询的不公平现象。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-08-20 DOI: 10.1038/s41372-025-02377-z

Samantha L. Simpson, Kylie Mena, DonnaMaria E. Cortezzo, Chunyan Liu, Shelley R. Ehrlich, Sarah Eaton, Ting Ting Fu, Andrew F. Beck, James M. Greenberg, Emily R. Miller

{"title":"Inequities in prenatal neonatology consultation in high-mortality neonatal populations","authors":"Samantha L. Simpson, Kylie Mena, DonnaMaria E. Cortezzo, Chunyan Liu, Shelley R. Ehrlich, Sarah Eaton, Ting Ting Fu, Andrew F. Beck, James M. Greenberg, Emily R. Miller","doi":"10.1038/s41372-025-02377-z","DOIUrl":"10.1038/s41372-025-02377-z","url":null,"abstract":"To explore inequities in prenatal consultation and parental resuscitation decisions across high-mortality conditions. We conducted a retrospective chart review of pregnant people whose liveborn neonates were diagnosed with high-mortality conditions. We examined two cohorts: periviable infants (22 0/7–24 6/7 weeks) and infants with severe congenital anomalies. A total of 194 neonates met eligibility criteria for the periviable cohort, 197 for the congenital anomaly cohort. In the periviable cohort, 94% of White vs. 81% of Black pregnant people received neonatology consultation (p = 0.009). A total of 96% of those with commercial insurance vs. 82% of those with Medicaid received consultation (p = 0.005). Half of Hispanic pregnant people did not receive neonatology consultation (p = 0.02). In the congenital anomaly cohort, pregnant people who spoke a language other than English were less likely to receive consultation (44% vs. 81%, p = 0.02). This regional assessment found previously unrecognized inequities in prenatal neonatology consultation.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":"45 9","pages":"1198-1206"},"PeriodicalIF":2.4,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12431841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Leveraging artificial intelligence for prediction of pulmonary hemorrhage in preterm infants 利用人工智能预测早产儿肺出血。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-08-20 DOI: 10.1038/s41372-025-02390-2

Hany Aly, Vanishree Nandakumar, Hasan Cetin, Hatem Eltaly, Tetyana Nesterenko, Mohamed A. Mohamed

{"title":"Leveraging artificial intelligence for prediction of pulmonary hemorrhage in preterm infants","authors":"Hany Aly, Vanishree Nandakumar, Hasan Cetin, Hatem Eltaly, Tetyana Nesterenko, Mohamed A. Mohamed","doi":"10.1038/s41372-025-02390-2","DOIUrl":"10.1038/s41372-025-02390-2","url":null,"abstract":"To identify clinical variables and indicators associated with pulmonary hemorrhage in preterm infants. This case-control study included inborn infants <32 weeks. Data were collected in 12-h epochs from birth until hemorrhage onset or up to 72 h for controls. Machine learning used the Random Forest algorithm. Statistical analysis included T test and Mann–Whitney U test. Among 1133 screened infants, 35 had hemorrhage. Mean gestational age was 25.6 ± 1.6 weeks, birth weight 753 ± 224 g, and median onset of hemorrhage was 44.5 h. Affected infants more often required chest compressions and invasive ventilation. Machine learning (accuracy = 83%, AUC = 90%) identified repeated surfactant dosing and postnatal hypotension in the first 12 h of life as top predictors, along with maternal and gestational age. Mortality was higher in cases than controls (19% vs. 3%, p = 0.005). Repeated surfactant dosing and early postnatal hypotension are key predictors for pulmonary hemorrhage in preterm infants.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":"45 10","pages":"1403-1410"},"PeriodicalIF":2.4,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41372-025-02390-2.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A clinician's musings on oxygen: Too little or too much with life in the balance. 一个临床医生对氧气的思考：太少或太多，生命的平衡。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-08-20 DOI: 10.1038/s41372-025-02398-8

David K Stevenson, Ronald J Wong, Jonathan D Reiss, Ivana Marić, Anca M Paşca, Terence L Ahern

引用次数: 0

Advanced thermoregulation by access port covers in neonatal transport incubators: computational fluid dynamics analysis. 先进的温度调节通过访问端口覆盖在新生儿运输孵化器：计算流体动力学分析。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-08-19 DOI: 10.1038/s41372-025-02393-z

Hisato Kobayashi, Gaku Tanaka, Takeshi Arimitsu

{"title":"Advanced thermoregulation by access port covers in neonatal transport incubators: computational fluid dynamics analysis.","authors":"Hisato Kobayashi, Gaku Tanaka, Takeshi Arimitsu","doi":"10.1038/s41372-025-02393-z","DOIUrl":"10.1038/s41372-025-02393-z","url":null,"abstract":"Objective: Covering access ports in transport incubators prevents internal temperature drops, but its effect on overall temperature distribution is unclear. We hypothesized that while covering access ports maintains central temperature, it may lead to temperature imbalances within the incubator.Study design: Airflow and temperature distributions were simulated using computational fluid dynamics in a three-dimensional model of a transport incubator with open, covered, and closed access port configurations.Results: Internal temperature decreased significantly with open ports, while central temperature remained stable with covered or closed ports. However, temperature distribution was heterogeneous with covered ports, showing higher temperatures in the upper and posterior regions and lower temperatures in the lower and anterior regions.Conclusion: Covering access ports reduces airflow and central temperature drop but fails to address uneven temperature distribution, emphasizing the need for design improvements to enhance neonatal care.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144883064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of hyperglycemia in extremely preterm infants with neurodevelopmental outcomes at 18 months of corrected age 极早产儿高血糖与矫正年龄18个月时神经发育结局的关系

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-08-18 DOI: 10.1038/s41372-025-02388-w

Yohei Minamitani, Kazusa Nakajima, Fumihiko Namba

引用次数: 0

Continuum of care for patients through medical-legal partnership: improving the transition from NICU stay to home. 通过医疗-法律伙伴关系为患者提供连续的护理：改善从新生儿重症监护病房到家庭的过渡。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-08-18 DOI: 10.1038/s41372-025-02380-4

Christine C Pazandak, Shetal Shah, Susan Schoppa

引用次数: 0

Antibiotic exposure and infection epidemiology among newborns with congenital diaphragmatic hernia 新生儿先天性膈疝抗生素暴露与感染流行病学。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-08-18 DOI: 10.1038/s41372-025-02389-9

Sabrina J. Flohr, Leny Mathew, Holly L. Hedrick, Natalie E. Rintoul, Talene A. Metjian, Sanjeev K. Swami, Jeffrey S. Gerber, Alexandra K. Medoro, Dustin D. Flannery

引用次数: 0

Perspectives of medical staff on respiratory management with neurally adjusted ventilatory assist in preterm infants. 医护人员对早产儿神经调节通气辅助呼吸管理的看法。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-08-16 DOI: 10.1038/s41372-025-02376-0

Yuta Kato, Seiichi Tomotaki, Katsuya Hirata, Yosuke Yamada, Arata Oda

{"title":"Perspectives of medical staff on respiratory management with neurally adjusted ventilatory assist in preterm infants.","authors":"Yuta Kato, Seiichi Tomotaki, Katsuya Hirata, Yosuke Yamada, Arata Oda","doi":"10.1038/s41372-025-02376-0","DOIUrl":"https://doi.org/10.1038/s41372-025-02376-0","url":null,"abstract":"Objective: This study aimed to examine physicians' and nurses' perspectives of neurally adjusted ventilatory assist (NAVA) and electrical activity of the diaphragm (Edi) in management of extremely low birth weight (ELBW) infants for further improvement of respiratory management and care.Study design: An anonymous survey about the effectiveness, benefits, and challenges of NAVA and Edi were conducted from December 2021 to February 2022 in 29 institutions in Japan.Result: A total of 497 responses (by 148 physicians and 349 nurses) from 22 institutions were analyzed. Most medical staff found NAVA and non-invasive NAVA beneficial, particularly for improving oxygenation and ventilation, though some physicians voiced concerns about potential respiratory condition worsening. Edi was considered important for assessing the respiratory status and facilitating communication between healthcare providers.Conclusion: While many physicians and nurses consider NAVA to have promising advantages for respiratory management of ELBW infants, its implementation requires comprehensive training and education.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144862297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0