Journal of Perinatology最新文献

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Experiences of communication in the neonatal intensive care unit for mothers with a preferred language other than English.
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-02-20 DOI: 10.1038/s41372-025-02229-w
Nikita S Kalluri, Rachel E Witt, Zuzanna Kubicka, Margaret G Parker, Erika G Cordova-Ramos
{"title":"Experiences of communication in the neonatal intensive care unit for mothers with a preferred language other than English.","authors":"Nikita S Kalluri, Rachel E Witt, Zuzanna Kubicka, Margaret G Parker, Erika G Cordova-Ramos","doi":"10.1038/s41372-025-02229-w","DOIUrl":"https://doi.org/10.1038/s41372-025-02229-w","url":null,"abstract":"<p><strong>Objective: </strong>To understand the experiences of mothers with a preferred language other than English (PLOE) in communicating with staff and engaging in the care of their hospitalized infant.</p><p><strong>Design: </strong>We qualitatively analyzed a previously collected and a prospective dataset comprised of transcripts of 36 interviews with Spanish-, Haitian Creole-, and Brazilian Portuguese-speaking mothers of preterm infants from 3 NICUs. We applied the constant comparative method to develop codes and themes, which were inductively structured using the socio-ecological framework.</p><p><strong>Results: </strong>We identified themes across socio-ecological levels: Individual (unaddressed language barriers, varied maternal empowerment, and justification of suboptimal interpreter use); Interpersonal (family-staff language concordance facilitating engagement, positive impact of non-interpreted informal interactions, and differential treatment based on maternal language status); Institutional (system-level interpretation barriers and varied interpreter service quality).</p><p><strong>Conclusion: </strong>Mothers with PLOE face multilevel communication and engagement barriers in the NICU; we discuss potential interventions to improve equity in these areas.</p>","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving Commitment to Family-Centered Care in the NICU: A Multicenter Collaborative Quality Improvement Project.
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-02-20 DOI: 10.1038/s41372-025-02232-1
Malathi Balasundaram, Henry C Lee, Laura C Hedli, Kerri Z Machut, Dharshi Sivakumar, Morgan Kowalski, Rafael Mendelsohn, Keira Sorrells, Colby Day
{"title":"Improving Commitment to Family-Centered Care in the NICU: A Multicenter Collaborative Quality Improvement Project.","authors":"Malathi Balasundaram, Henry C Lee, Laura C Hedli, Kerri Z Machut, Dharshi Sivakumar, Morgan Kowalski, Rafael Mendelsohn, Keira Sorrells, Colby Day","doi":"10.1038/s41372-025-02232-1","DOIUrl":"10.1038/s41372-025-02232-1","url":null,"abstract":"<p><strong>Objective: </strong>Despite evidence demonstrating the positive impact of family-centered care (FCC) in the neonatal intensive care unit (NICU), FCC is not standard of care. This multi-center, quality improvement initiative aimed to increase the percentage of NICUs with FCC committees and Family Partnership Councils (FPCs).</p><p><strong>Study design: </strong>Participating NICUs were divided into small groups for collaborative mentoring. A key driver diagram and Pareto charts evaluated barriers to FCC and directed interventions. The primary outcome measure was development of an FCC committee and/or FPC. Process measures were views of bi-monthly educational webinars, evaluated using Statistical Process Control charts.</p><p><strong>Result: </strong>Across 22 NICUs, the percentage with FCC committees and FPCs increased from 18% to 59% and 18% to 45%, respectively. Average webinar views increased from 28 to 182 views/webinar with clear signal on XmR chart.</p><p><strong>Conclusion: </strong>A collaborative mentoring model and focused education achieved the goal of increasing NICU FCC committees and FPCs.</p>","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A budget impact analysis of an expanded criteria for pasteurized donor human milk use: a single center experience.
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-02-20 DOI: 10.1038/s41372-025-02235-y
Dylan G Choi, Kelly Stapleton, Cynthia L Gong, Stephanie A Schnell, Leah Yieh
{"title":"A budget impact analysis of an expanded criteria for pasteurized donor human milk use: a single center experience.","authors":"Dylan G Choi, Kelly Stapleton, Cynthia L Gong, Stephanie A Schnell, Leah Yieh","doi":"10.1038/s41372-025-02235-y","DOIUrl":"https://doi.org/10.1038/s41372-025-02235-y","url":null,"abstract":"","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Human milk derived fortifiers are associated with glucose, phosphorus, and calcium derangements.
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-02-20 DOI: 10.1038/s41372-025-02241-0
Danielle Ackley, Jiamin Yin, Carl D'Angio, Jeffrey Meyers, Bridget Young
{"title":"Correction: Human milk derived fortifiers are associated with glucose, phosphorus, and calcium derangements.","authors":"Danielle Ackley, Jiamin Yin, Carl D'Angio, Jeffrey Meyers, Bridget Young","doi":"10.1038/s41372-025-02241-0","DOIUrl":"https://doi.org/10.1038/s41372-025-02241-0","url":null,"abstract":"","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of using dexmedetomidine versus morphine as sedation on long-term neurodevelopmental outcomes of encephalopathic neonates undergoing therapeutic hypothermia.
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-02-20 DOI: 10.1038/s41372-025-02227-y
Tatiana A Nuzum, Sadaf H Kazmi, Elena V Wachtel
{"title":"The effect of using dexmedetomidine versus morphine as sedation on long-term neurodevelopmental outcomes of encephalopathic neonates undergoing therapeutic hypothermia.","authors":"Tatiana A Nuzum, Sadaf H Kazmi, Elena V Wachtel","doi":"10.1038/s41372-025-02227-y","DOIUrl":"https://doi.org/10.1038/s41372-025-02227-y","url":null,"abstract":"<p><strong>Objective: </strong>To compare neurodevelopmental outcomes using Bayley Scales of Infant Development (BSID), between encephalopathic neonates undergoing therapeutic hypothermia (TH), sedated with either continuous dexmedetomidine or intermittent morphine.</p><p><strong>Study design: </strong>Retrospective, observational cohort study including encephalopathic neonates born between 2014 - 2022 that underwent TH at two Regional Perinatal Centres, and completed neurodevelopmental follow-up assessments.</p><p><strong>Results: </strong>There were no significant differences in demographics or short-term neurologic outcomes between morphine (n = 30) and dexmedetomidine (n = 32) groups. At 12 months, median motor composite scores (104 vs 98.5, p = 0.02) and median fine motor scaled scores (SS) (11 vs 10, p = 0.01) were significantly higher in the dexmedetomidine group. Median expressive language SS were slightly higher in the morphine group (11 v 10, p = 0.05). BSID scores at 18-24 months were similar.</p><p><strong>Conclusion: </strong>This study supports the use of dexmedetomidine as first-line sedation agent during TH, given comparable 18-24 month neurodevelopmental outcomes.</p>","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perfluoroalkyl substances and preterm birth.
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-02-18 DOI: 10.1038/s41372-025-02231-2
Anne M Mullin, Abby F Fleisch, Clementina Mesaros, Rachel Ledyard, Michele R Hacker, Heather H Burris
{"title":"Perfluoroalkyl substances and preterm birth.","authors":"Anne M Mullin, Abby F Fleisch, Clementina Mesaros, Rachel Ledyard, Michele R Hacker, Heather H Burris","doi":"10.1038/s41372-025-02231-2","DOIUrl":"10.1038/s41372-025-02231-2","url":null,"abstract":"","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between cardiovascular care and neurodevelopmental outcomes in infants with neonatal encephalopathy and hemodynamic instability.
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-02-17 DOI: 10.1038/s41372-025-02230-3
Kata Kovacs, Regan E Giesinger, Zsuzsanna Varga, Miklos Szabo, Agnes Jermendy, Patrick J McNamara
{"title":"Association between cardiovascular care and neurodevelopmental outcomes in infants with neonatal encephalopathy and hemodynamic instability.","authors":"Kata Kovacs, Regan E Giesinger, Zsuzsanna Varga, Miklos Szabo, Agnes Jermendy, Patrick J McNamara","doi":"10.1038/s41372-025-02230-3","DOIUrl":"https://doi.org/10.1038/s41372-025-02230-3","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the approach to cardiovascular care and long-term outcomes in infants undergoing hypothermia for neonatal encephalopathy (NE).</p><p><strong>Study design: </strong>This is a retrospective cohort study of 152 infants with NE [SickKids Hospital (Center A, n = 74) or Semmelweis University (Center B, n = 78)], who developed hypotension and underwent neonatal follow-up. Primary outcome was defined as death or neurodevelopmental impairment (<70 on Bayley-II or <85 points on Bayley-III test).</p><p><strong>Result: </strong>The presence of hypoxic injury in the brain MRI increased the odds of adverse outcome by 10.5 fold. In addition, for every 24 h increase in the duration of cardiovascular support the odds of adverse outcome increased by 12%. In a subgroup of patients with detailed echocardiography evaluation lower tricuspid annulus plane systolic excursion was noted in the non-survivors.</p><p><strong>Conclusion: </strong>Hypoxic brain injury and longer cardiovascular therapy are independently associated with the adverse long-term outcome in patients with NE.</p>","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identifying barriers to complying with new restrictive NICU transfusion guidelines.
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-02-16 DOI: 10.1038/s41372-025-02225-0
Sarah M Tweddell, Thomas M Morelli, Timothy M Bahr, Ashley Krueger, Robert D Christensen, Robin K Ohls
{"title":"Identifying barriers to complying with new restrictive NICU transfusion guidelines.","authors":"Sarah M Tweddell, Thomas M Morelli, Timothy M Bahr, Ashley Krueger, Robert D Christensen, Robin K Ohls","doi":"10.1038/s41372-025-02225-0","DOIUrl":"https://doi.org/10.1038/s41372-025-02225-0","url":null,"abstract":"<p><strong>Objectives: </strong>Our NICU transfusion stewardship group proposed new, more restrictive guidelines for red blood cell and platelet transfusions. To evaluate our clinician's support for these, we conducted a series of structured interviews.</p><p><strong>Study design: </strong>We presented 11 scenarios involving the new guidelines to each of 24 clinicians. After every scenario we asked whether they would abide by the guideline, and if not, why.</p><p><strong>Results: </strong>For 88% of scenarios, participants said they supported the guideline and would not transfuse. The most common reasons for wanting to transfuse when the guidelines said not to were; 1) the scenario-patient did not meet the guideline but was \"close\" and 2) the guideline was insufficiently explicit.</p><p><strong>Conclusions: </strong>Structured interviews like these can identify barriers to complying with transfusion guidelines and can suggest guideline modifications. Future studies will determine the effect of this discovery process on guideline adherence and patient outcomes.</p>","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early hydrocortisone verses placebo in neonatal shock- a double blind Randomized controlled trial
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-02-13 DOI: 10.1038/s41372-025-02222-3
Sankalp Dudeja, Shiv Sajan Saini, Venkataseshan Sundaram, Sourabh Dutta, Naresh Sachdeva, Praveen Kumar
{"title":"Early hydrocortisone verses placebo in neonatal shock- a double blind Randomized controlled trial","authors":"Sankalp Dudeja,&nbsp;Shiv Sajan Saini,&nbsp;Venkataseshan Sundaram,&nbsp;Sourabh Dutta,&nbsp;Naresh Sachdeva,&nbsp;Praveen Kumar","doi":"10.1038/s41372-025-02222-3","DOIUrl":"10.1038/s41372-025-02222-3","url":null,"abstract":"To compare early hydrocortisone (initiated along with vasoactive therapy) vs. placebo for all-cause mortality within next 14 days among neonates with fluid-refractory shock. Neonates with fluid-refractory shock were randomly assigned to receive hydrocortisone or saline placebo alongside vasoactive drugs. If they developed catecholamine-resistant shock, the study drug was replaced with open-label hydrocortisone. Eighty-four neonates were randomized (early hydrocortisone=43 and placebo=41). Median gestational age of our cohort (n = 84) was 30.3 weeks [interquartile range (IQR): 27.7, 32.5] and median birth weight was 1148 grams (IQR: 860, 1419). The 14-day all-cause mortality was comparable between early hydrocortisone and placebo groups [OR 0.53 (95% CI 0.19, 1.52)]. Both groups had similar duration of vasoactive drugs and vasoactive-inotrope scores, incidence of adverse effects of hydrocortisone and incidence of medium-term complications. We did not observe a significant reduction in 14-day mortality with early hydrocortisone compared to placebo in fluid-refractory neonatal shock.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":"45 3","pages":"342-349"},"PeriodicalIF":2.4,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143414615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immediate heart rate changes in late preterm infants receiving resuscitation in the delivery room.
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-02-13 DOI: 10.1038/s41372-025-02220-5
Yafa Davydova, Dina Elachi, Rebecca Miller, Charlene Thomas, Corrina Oxford, Jeffrey Perlman
{"title":"Immediate heart rate changes in late preterm infants receiving resuscitation in the delivery room.","authors":"Yafa Davydova, Dina Elachi, Rebecca Miller, Charlene Thomas, Corrina Oxford, Jeffrey Perlman","doi":"10.1038/s41372-025-02220-5","DOIUrl":"https://doi.org/10.1038/s41372-025-02220-5","url":null,"abstract":"<p><strong>Objectives: </strong>Assess heart rate (HR) trends in the minutes following delivery in late preterm infants 34-36 6/7 weeks with spontaneous respirations and compare trends in infants with delayed transition requiring interventions and assess the direct potential impact of these interventions on HR changes.</p><p><strong>Design: </strong>Prospective observational single center study in 20 late preterm infants born via cesarean section utilizing the NeoBeat which uses dry electrode technology to obtain blinded HR measures in infants with spontaneous respirations versus infants requiring interventions i.e.: positive pressure ventilation, continuous positive airway pressure or suctioning.</p><p><strong>Results: </strong>Initial HR in spontaneously breathing infants (n = 8) was higher versus those requiring interventions, differences that persisted through five minutes. Iatrogenic bradycardia ranging from 65 to 90 beats/minute was induced by interventions in five(42%) of 12 infants.</p><p><strong>Conclusions: </strong>Initial HR in spontaneously breathing late preterm infants was significantly higher compared to infants who received interventions. Respiratory interventions induced sudden unanticipated bradycardia in many cases.</p>","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143414617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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