Journal of Perinatology最新文献_第5页

Gestational diabetes detection thresholds and infant growth, nutrition, and neurodevelopment at 12-18 months: a prospective cohort study within a randomized trial 妊娠糖尿病检测阈值与12-18个月婴儿生长、营养和神经发育：一项随机试验中的前瞻性队列研究

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-09-05 DOI: 10.1038/s41372-025-02406-x

Francesca Amitrano, Komal Manerkar, Jane M. Alsweiler, Cathryn A. Conlon, Caroline A. Crowther, Richard Edlin, Jane E. Harding, Lesley ME McCowan, Michael P. Meyer, Janet A. Rowan, Elaine C. Rush, Christopher JD McKinlay

{"title":"Gestational diabetes detection thresholds and infant growth, nutrition, and neurodevelopment at 12-18 months: a prospective cohort study within a randomized trial","authors":"Francesca Amitrano, Komal Manerkar, Jane M. Alsweiler, Cathryn A. Conlon, Caroline A. Crowther, Richard Edlin, Jane E. Harding, Lesley ME McCowan, Michael P. Meyer, Janet A. Rowan, Elaine C. Rush, Christopher JD McKinlay","doi":"10.1038/s41372-025-02406-x","DOIUrl":"10.1038/s41372-025-02406-x","url":null,"abstract":"To assess the impact of gestational diabetes(GDM) detection thresholds on infant growth, nutrition, and neurodevelopment at 12-18 months. Prospective cohort study within the GEMS trial(ACTRN12615000290594), which randomized pregnant women to detection of GDM using lower or higher glycemic criteria. The main outcomes were overweight/rapid weight gain; food approach appetitive score; energy intake; cognitive z-score. Compared to control infants, those exposed to GDM detected and treated by higher criteria or by lower but not higher criteria that was untreated, were less likely to have increased overweight/rapid weight gain, possibly with lower energy intake. There were no important differences in appetite and cognition. Infants exposed to GDM by lower but not higher criteria that was treated were similar to controls. Exposure to treated GDM or untreated GDM detected by lower but not higher criteria, was not associated with increased infant risk factors for obesity or adverse cognitive outcomes.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":"45 10","pages":"1360-1369"},"PeriodicalIF":2.4,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41372-025-02406-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dexmedetomidine's effect on neonatal sedation, pain, respiratory status and cardiovascular system. 右美托咪定对新生儿镇静、疼痛、呼吸状态和心血管系统的影响。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-09-04 DOI: 10.1038/s41372-025-02339-5

Marjorie M Makoni, Ivonne Sierra-Strum, Adrianne R Bischoff, Jamie L Miller, Lise DeShea, William Howard Beasley, Edgardo Szyld

引用次数: 0

Pneumothorax in newborns: a cohort study from three NICUs. 新生儿气胸：来自三个新生儿重症监护病房的队列研究。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-09-04 DOI: 10.1038/s41372-025-02408-9

Mohsen A A Farghaly, Mahmoud A M Ali, Ceyda Acun, Vanishree Nandakumar, Hatem Eltaly, Mohamed A Mohamed, Hany Aly

{"title":"Pneumothorax in newborns: a cohort study from three NICUs.","authors":"Mohsen A A Farghaly, Mahmoud A M Ali, Ceyda Acun, Vanishree Nandakumar, Hatem Eltaly, Mohamed A Mohamed, Hany Aly","doi":"10.1038/s41372-025-02408-9","DOIUrl":"https://doi.org/10.1038/s41372-025-02408-9","url":null,"abstract":"Objective: To assess pneumothorax prevalence in neonates across gestational age (GA) categories, identify associated variables, and examine the impact of bubble CPAP (b-CPAP) implementation.Study design: A cohort of 58,706 infants born at three hospitals over six years was analyzed, grouped by GA: ≥35 weeks, 29-34 weeks, and ≤28 weeks. Pneumothorax cases were matched with controls, and prevalence before and after b-CPAP adoption was compared.Results: Pneumothorax occurred in 310 infants (0.53%): 0.39% in ≥35 weeks, 4.0% in 29-34 weeks, and 4.6% in ≤28 weeks GA. Most cases occurred within 24 hours of birth, especially in ≥35 weeks (76%). In the ≥35-week group, pneumothorax was associated with male sex, chorioamnionitis, and delivery room CPAP. In the 29-34-week group, it was linked to small for gestational age, maternal diabetes, and surfactant use. In ≤28-week infants, delivery room intubation was the primary risk factor. Pneumothorax prevalence in non-intubated infants was unchanged after b-CPAP implementation (0.35% vs. 0.41%; aOR = 0.85, 95% CI: 0.62-1.16; P = 0.35).Conclusion: Delivery room interventions, not NICU b-CPAP use, were associated with neonatal pneumothorax.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physiology-guided vasoactive therapy in neonates: rethinking dopamine as first-line 新生儿生理引导血管活性治疗：重新思考多巴胺作为第一线。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-09-04 DOI: 10.1038/s41372-025-02407-w

Audrey Hébert, Satyan Lakshminrusimha, Danielle R. Rios, Shazia Bhombal, Shiran Sara Moore, Stephanie Ford, Gabriel Altit

引用次数: 0

Risk factors associated with the development of necrotizing enterocolitis in preterm infants on an exclusive human milk diet: a single-center case-control study. 纯母乳喂养的早产儿发生坏死性小肠结肠炎的相关危险因素：一项单中心病例对照研究

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-08-30 DOI: 10.1038/s41372-025-02401-2

Haider Ailumerab, Jamie L Miller, Lise DeShea, William Howard Beasley, Hala Chaaban, Erynn M Bergner

{"title":"Risk factors associated with the development of necrotizing enterocolitis in preterm infants on an exclusive human milk diet: a single-center case-control study.","authors":"Haider Ailumerab, Jamie L Miller, Lise DeShea, William Howard Beasley, Hala Chaaban, Erynn M Bergner","doi":"10.1038/s41372-025-02401-2","DOIUrl":"https://doi.org/10.1038/s41372-025-02401-2","url":null,"abstract":"Objective: Identify early neonatal and maternal risk factors for development of necrotizing enterocolitis (NEC) in preterm infants receiving an exclusive human milk diet (EHMD).Study design: Preterm infants who developed NEC stage ≥2 while receiving an EHMD were compared to matched controls who did not develop NEC on the same diet. Predictors of NEC were selected for multiple-predictor logistic regression analysis based on literature or significance in single-predictor models.Results: A total of 27 cases and 98 controls (mean GA = 27 weeks) were included. Groups did not differ significantly on baseline characteristics. Maternal urinary tract infection, maternal neutrophil-to-lymphocyte ratio before delivery, and vasopressor use during the first week significantly predicted NEC.Conclusion: Despite the use of EHMD, NEC remains a concern, underlining its multifactorial nature. Results highlight the potential role of maternal inflammation and early neonatal hemodynamic instability in NEC development. Findings could inform future research aimed at identifying high-risk infants.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dopamine versus epinephrine for neonatal septic shock: an open labeled, randomized controlled trial 多巴胺与肾上腺素治疗新生儿感染性休克：一项开放标记、随机对照试验。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-08-28 DOI: 10.1038/s41372-025-02399-7

Gurarsh Singh, Vikram Bhaskar, Prerna Batra, Piyush Gupta

引用次数: 0

Impact of prophylactic antibiotic duration on surgical site infection rate in neonatal surgery: a multicenter retrospective observational study 预防性抗生素持续时间对新生儿外科手术部位感染率的影响：一项多中心回顾性观察研究。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-08-27 DOI: 10.1038/s41372-025-02400-3

Tomohiro Sunouchi, Jun Fujishiro, Koji Oba, Tetsuya Ishimaru, Chikara Ogimi, Hiroshi Kawashima, Akira Nishi, Kenichi Maruyama, Kiyoshi Tanaka, Hajime Takayasu, Yujiro Tanaka, Kazuko Obana, Ryu Yoneda, Akio Ishiguro, Yutaka Matsuyama

{"title":"Impact of prophylactic antibiotic duration on surgical site infection rate in neonatal surgery: a multicenter retrospective observational study","authors":"Tomohiro Sunouchi, Jun Fujishiro, Koji Oba, Tetsuya Ishimaru, Chikara Ogimi, Hiroshi Kawashima, Akira Nishi, Kenichi Maruyama, Kiyoshi Tanaka, Hajime Takayasu, Yujiro Tanaka, Kazuko Obana, Ryu Yoneda, Akio Ishiguro, Yutaka Matsuyama","doi":"10.1038/s41372-025-02400-3","DOIUrl":"10.1038/s41372-025-02400-3","url":null,"abstract":"To evaluate the relationship between the incidence of surgical site infections (SSIs) and the duration of perioperative antibiotic prophylaxis (PAP) in neonatal surgery, and to identify risk factors for SSIs in neonates. Eligible patients were neonates who underwent surgical procedures—primarily in the respiratory and gastrointestinal fields—between January 2014 and December 2023 at seven institutions. All data were retrospectively retrieved from electronic patient records. We estimated the risk difference using a modified least-squares regression model. Of the 983 patients included, 91 (9%) developed SSIs. A total of 735 patients (75%) received PAP for >24 h. There was no significant difference in risk when PAP duration was <24 h compared with ≥24 h. Independent risk factors for SSIs were an operative time exceeding 120 min, past surgical history, and open surgery. In neonatal surgery, a short duration (<24 h) of PAP may not increase the risk of SSI.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":"45 10","pages":"1443-1449"},"PeriodicalIF":2.4,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41372-025-02400-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The aortic valve as a landmark for ultrasound guided umbilical artery catheter placement, a prospective retrospective controlled study. 主动脉瓣作为超声引导脐动脉导管置入的一个里程碑，一项前瞻性回顾性对照研究。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-08-26 DOI: 10.1038/s41372-025-02402-1

Mohamed Sakr, Orna Rosen, Mimi Kim, Mamta Fuloria, Megan Carney, Sheri Nemerofsky

{"title":"The aortic valve as a landmark for ultrasound guided umbilical artery catheter placement, a prospective retrospective controlled study.","authors":"Mohamed Sakr, Orna Rosen, Mimi Kim, Mamta Fuloria, Megan Carney, Sheri Nemerofsky","doi":"10.1038/s41372-025-02402-1","DOIUrl":"https://doi.org/10.1038/s41372-025-02402-1","url":null,"abstract":"Objective: Umbilical artery catheters (UAC) are common in the neonatal intensive care unit. Catheters are often re-adjusted and require multiple X-rays. Point of care ultrasound (POCUS) is reliable and safe. The objective of this study was to determine if visualizing the aortic valve (AoV) with POCUS could be a landmark for UAC positioning.Study design: This was a prospective, retrospective controlled study. The retrospective group included neonates with a UAC insertion depth calculated by (3×birth weight(kg)+9). The experimental group used POCUS and identified the level of the AoV for UAC placement.Results: Each group had thirty neonates and were similar in gestational age, and median birth weight. In the control group, 16 neonates (53%) required repositioning and between 2 and 6 X-Rays. None of the UACs in the experimental group needed repeat X-Rays (p < 0.001).Conclusion: The AoV location identified using POCUS can reduce the need for multiple XRs for UAC placement.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ethical considerations in quality improvement. 质量改进中的伦理考虑。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-08-26 DOI: 10.1038/s41372-025-02403-0

Stephen A Pearlman, Peter D Murray, Roopali Bapat

引用次数: 0

Prenatal counseling for heart disease: Perception of understanding and communication gaps 心脏病产前咨询：理解和沟通差距的感知。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-08-21 DOI: 10.1038/s41372-025-02365-3

Katherine J. DeWeert, Melissa K. Cousino, Sunkyung Yu, Sarah Gelehrter

{"title":"Prenatal counseling for heart disease: Perception of understanding and communication gaps","authors":"Katherine J. DeWeert, Melissa K. Cousino, Sunkyung Yu, Sarah Gelehrter","doi":"10.1038/s41372-025-02365-3","DOIUrl":"10.1038/s41372-025-02365-3","url":null,"abstract":"Research on parental understanding following prenatal counseling for congenital heart disease (CHD) is limited. We aimed to evaluate parental knowledge of their fetus’ CHD diagnosis and congruence between physician’s and parent’s assessments of parental understanding. Paired surveys of pediatric cardiologists and parents of fetuses requiring neonatal heart surgery assessed parental knowledge and perceived understanding of diagnosis, treatment and complications. Gwet’s agreement coefficients (GAC) were used to examine congruence. There was good congruence between 40 participating parents and cardiologists regarding knowledge of the diagnosis (GAC 0.89), need for neonatal surgery (GAC 0.81), need for further surgeries and lifelong care (GAC 0.66 and 0.65). While cardiologists perceived parents understood risk of mortality and neurodevelopmental outcomes, parental knowledge was poor (GAC −0.04 and 0.05, respectively). For many aspects of counseling, parental knowledge is congruent with cardiologist’s perceptions; however, communication gaps exist for knowledge of mortality and other longer-term outcomes.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":"45 9","pages":"1207-1212"},"PeriodicalIF":2.4,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12431847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0