Journal of Perinatology最新文献

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Seeing beyond the obvious: pragmatic skin care guidance for infants 22-24 weeks gestational age. 超越表象:针对22-24周胎龄婴儿的实用护肤指导。
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-09-16 DOI: 10.1038/s41372-025-02375-1
Vita Boyar, Marty Visscher, Carolyn Lund, Vivek Narendran
{"title":"Seeing beyond the obvious: pragmatic skin care guidance for infants 22-24 weeks gestational age.","authors":"Vita Boyar, Marty Visscher, Carolyn Lund, Vivek Narendran","doi":"10.1038/s41372-025-02375-1","DOIUrl":"https://doi.org/10.1038/s41372-025-02375-1","url":null,"abstract":"<p><p>During the past decade, infants born as early as 22-24 weeks' gestation have been admitted to neonatal intensive care units in increasing numbers. This has facilitated a need for greater understanding of skin physiology and structure, as well as of influences of the surrounding environment on maturation. This article aims to elaborate the physiology of skin for infants born ≤24 weeks' gestation and the effects of common clinical practices to prevent and treat iatrogenic wounds. We summarize the evidence, where available, and describe clinical experience.</p>","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145069870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in incidence of gastroschisis before and after the start of the COVID-19 pandemic. COVID-19大流行开始前后胃裂病发病率的趋势。
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-09-12 DOI: 10.1038/s41372-025-02413-y
Nicola Perlman, Elizabeth B Sherwin, Stephanie A Leonard, Deirdre J Lyell, Jochen Profit, Yair J Blumenfeld
{"title":"Trends in incidence of gastroschisis before and after the start of the COVID-19 pandemic.","authors":"Nicola Perlman, Elizabeth B Sherwin, Stephanie A Leonard, Deirdre J Lyell, Jochen Profit, Yair J Blumenfeld","doi":"10.1038/s41372-025-02413-y","DOIUrl":"https://doi.org/10.1038/s41372-025-02413-y","url":null,"abstract":"","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145054207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute kidney injury and subsequent risk of late-onset infection among extremely low gestational age newborns 极低胎龄新生儿急性肾损伤及继发迟发性感染风险
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-09-11 DOI: 10.1038/s41372-025-02410-1
Megan J. Turner, Russell Griffin, Meredith Schuh, Keia Sanderson, Cara Slagle, Shina Menon, David Askenazi, Katja Gist
{"title":"Acute kidney injury and subsequent risk of late-onset infection among extremely low gestational age newborns","authors":"Megan J. Turner,&nbsp;Russell Griffin,&nbsp;Meredith Schuh,&nbsp;Keia Sanderson,&nbsp;Cara Slagle,&nbsp;Shina Menon,&nbsp;David Askenazi,&nbsp;Katja Gist","doi":"10.1038/s41372-025-02410-1","DOIUrl":"10.1038/s41372-025-02410-1","url":null,"abstract":"Determine whether acute kidney injury (AKI) is associated with subsequent late-onset infection (LOI) among extremely low gestational age newborns (ELGAN). Secondary analysis of participants in the Preterm Erythropoietin for Neuroprotection Trial. Infants surviving ≥7 days with sufficient serum creatinine data were included. The primary outcome was any LOI, starting ≥72 h after AKI. Time-varying Cox proportional hazards modeling estimated adjusted hazard ratios of AKI and LOI. 332/872 (38%) study infants experienced AKI. 552/872 (63%) experienced LOI. 336/552 (60.9%) of late-onset infections were culture-positive, and 216/552 (39.1%) were culture-negative. After adjusting for gestational age, sex, postnatal steroids, vancomycin/gentamicin receipt ≥72 h, birthweight, and 5-min APGAR, any AKI was associated with 1.47x increased hazard of subsequent LOI (adjusted HR: 1.47; 95% CI: 1.15–1.87). Prior AKI increased hazard of subsequent LOI in a large cohort of ELGANs. Clinicians may anticipate higher risk of infectious complications after AKI.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":"45 10","pages":"1450-1455"},"PeriodicalIF":2.4,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Government-administered benefit programs: missed opportunities to address poverty in the NICU. 政府管理的福利计划:错失了解决新生儿重症监护室贫困问题的机会。
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-09-10 DOI: 10.1038/s41372-025-02409-8
John Feister, Emily R Miller, Ndidi Unaka, Andrew F Beck
{"title":"Government-administered benefit programs: missed opportunities to address poverty in the NICU.","authors":"John Feister, Emily R Miller, Ndidi Unaka, Andrew F Beck","doi":"10.1038/s41372-025-02409-8","DOIUrl":"https://doi.org/10.1038/s41372-025-02409-8","url":null,"abstract":"","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Standardizing early cerebral palsy detection in high-risk infants: reducing age at diagnosis through a quality improvement initiative. 规范高危婴儿早期脑瘫检测:通过提高质量倡议降低诊断年龄。
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-09-09 DOI: 10.1038/s41372-025-02412-z
Sylvan Ryder, Mallory Kerner-Rossi, Sandhya Brachio, Lisa Yoon, Kathleen Brennan, Jennifer Hammond, Gabriella Paskin, Annette Zygmunt, Anketil Abreu, Shelagh O'Neill, Patricia Ryan, Joan Wagner, Anna Penn, Faith Kim
{"title":"Standardizing early cerebral palsy detection in high-risk infants: reducing age at diagnosis through a quality improvement initiative.","authors":"Sylvan Ryder, Mallory Kerner-Rossi, Sandhya Brachio, Lisa Yoon, Kathleen Brennan, Jennifer Hammond, Gabriella Paskin, Annette Zygmunt, Anketil Abreu, Shelagh O'Neill, Patricia Ryan, Joan Wagner, Anna Penn, Faith Kim","doi":"10.1038/s41372-025-02412-z","DOIUrl":"https://doi.org/10.1038/s41372-025-02412-z","url":null,"abstract":"<p><strong>Objective: </strong>To screen high-risk infants for CP in a level IV NICU and high-risk infant follow-up (HRIF) clinic.</p><p><strong>Study design: </strong>By using quality improvement methodology, we implemented the General Movement Assessment (GMA) and Hammersmith Infant Neurological Examination (HINE) to screen for CP and lower age at diagnosis. Main balancing measures included no-show rates.</p><p><strong>Results: </strong>Within the first year, 89% of infants had a GMA in the NICU, 100% in HRIF and 87% had a HINE in HRIF. Median age at diagnosis decreased from 18.5 months adjusted [16.7,19.4] in 2021 to 7.5 months [5.9,14.4; p = 0.01] in 2022 and 8.9 months [6.6,12.2; p = 0.01] in 2023. No-show rates increased in 2022 compared to 2021 (24% vs 17%, p = 0.02).</p><p><strong>Conclusions: </strong>By implementing and continuously improving a standard process in the NICU and HRIF, we demonstrated a successful increase in screening for CP leading to a lower age at diagnosis sustained for two years.</p>","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145030034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The feasibility of noninvasive blood pressure monitoring in infants with a birth weight under 500 grams. 对出生体重低于500克的婴儿进行无创血压监测的可行性。
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-09-09 DOI: 10.1038/s41372-025-02415-w
Soo Hyun Kim, Euiseok Jung, Hyo Myung Han, Ka Young Lee, Sookyoung Lee, Eun A Heo, Min-Ju Kim, Jung-Bok Lee, Byong Sop Lee, Ellen Ai-Rhan Kim, Ki-Soo Kim
{"title":"The feasibility of noninvasive blood pressure monitoring in infants with a birth weight under 500 grams.","authors":"Soo Hyun Kim, Euiseok Jung, Hyo Myung Han, Ka Young Lee, Sookyoung Lee, Eun A Heo, Min-Ju Kim, Jung-Bok Lee, Byong Sop Lee, Ellen Ai-Rhan Kim, Ki-Soo Kim","doi":"10.1038/s41372-025-02415-w","DOIUrl":"https://doi.org/10.1038/s41372-025-02415-w","url":null,"abstract":"<p><strong>Objective: </strong>To quantify agreement between oscillometric non-invasive blood pressure (NIBP) and invasive arterial blood pressure (IBP) in infants <500 g during the first postnatal week.</p><p><strong>Study design: </strong>Retrospective cohort of infants with a birth weight <500 g admitted to a tertiary NICU (2011-2023). Paired IBP-NIBP readings obtained within 1 min were analyzed. Bland-Altman plots quantified bias and 95% limits of agreement for systolic (SBP), diastolic (DBP) and mean arterial pressure (MAP).</p><p><strong>Results: </strong>Thirty-six infants (median gestation of 26.2 weeks) contributed 337 paired measurements. Mean (±SD) IBP vs. NIBP were 47.3  ±  10.4 vs. 49.4  ±  9.3 mm Hg (SBP), 29.2  ±  7.0 vs. 28.3  ±  8.2 mm Hg (DBP) and 35.1  ±  7.7 vs. 35.2  ±  7.9 mm Hg (MAP). Mean bias was +2.1 ±  6.8 mm Hg (SBP), -0.9  ±  6.7 mm Hg (DBP) and +0.1 ± 5.4 mm Hg (MAP), satisfying AAMI/ESH/ISO criteria (≤5 mm Hg mean difference, ≤8 mm Hg SD). Bias remained <3 mm Hg without inotropes; MAP bias rose to +1.3 mm Hg with inotropic support.</p><p><strong>Conclusion: </strong>Oscillometric NIBP compared to IBP provided acceptable agreement in hemodynamically stable neonates <500 g. Whereas, invasive arterial monitoring remains preferable in unstable neonates.</p>","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145030084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A survey of level 3 NICUs in Utah to the June 2025 American Academy of Pediatrics Committee on Fetus and Newborn clinical report on postnatal cord blood sampling. 犹他州3级新生儿重症监护病房的调查到2025年6月美国儿科学会胎儿和新生儿委员会关于产后脐带血采样的临床报告。
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-09-08 DOI: 10.1038/s41372-025-02418-7
Robin K Ohls, Timothy M Bahr, David A Kaufman, Robert D Christensen
{"title":"A survey of level 3 NICUs in Utah to the June 2025 American Academy of Pediatrics Committee on Fetus and Newborn clinical report on postnatal cord blood sampling.","authors":"Robin K Ohls, Timothy M Bahr, David A Kaufman, Robert D Christensen","doi":"10.1038/s41372-025-02418-7","DOIUrl":"https://doi.org/10.1038/s41372-025-02418-7","url":null,"abstract":"","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145030074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Meconium obstruction of prematurity in tiny babies - towards developing an international consensus. 小婴儿早产的胎便梗阻——正在形成国际共识。
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-09-08 DOI: 10.1038/s41372-025-02395-x
Graeme J Pitcher, Akio Kubota, Noelle E Younge, Christoph Bührer, C Michael Cotten, Katrin Mehler, Timothy J Boly, Riad Rahhal, Satoshi Kusuda, Matthew A Rysavy
{"title":"Meconium obstruction of prematurity in tiny babies - towards developing an international consensus.","authors":"Graeme J Pitcher, Akio Kubota, Noelle E Younge, Christoph Bührer, C Michael Cotten, Katrin Mehler, Timothy J Boly, Riad Rahhal, Satoshi Kusuda, Matthew A Rysavy","doi":"10.1038/s41372-025-02395-x","DOIUrl":"https://doi.org/10.1038/s41372-025-02395-x","url":null,"abstract":"<p><p>Intestinal perforation occurring in extremely low gestational age neonates is a devastating complication, associated with high mortality and morbidity. Multiple phenotypes of bowel perforation in premature infants have been described, with the most common being spontaneous, or isolated, intestinal perforation and perforated necrotizing enterocolitis. The purpose of this article is to summarize literature describing \"meconium obstruction of prematurity\", increasingly recognized as a distinct clinical phenotype in the smallest and most immature neonates. The goal of this review is to improve international recognition and understanding of this high-risk clinical condition. The lack of standardized nomenclature has been an obstacle to progress in understanding, preventing, and treating this important and more frequently encountered condition. The recognition of meconium obstruction requiring medical or surgical management is a clear distinguishing factor from other bowel pathologies of prematurity.</p>","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145030005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gestational diabetes detection thresholds and infant growth, nutrition, and neurodevelopment at 12-18 months: a prospective cohort study within a randomized trial 妊娠糖尿病检测阈值与12-18个月婴儿生长、营养和神经发育:一项随机试验中的前瞻性队列研究
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-09-05 DOI: 10.1038/s41372-025-02406-x
Francesca Amitrano, Komal Manerkar, Jane M. Alsweiler, Cathryn A. Conlon, Caroline A. Crowther, Richard Edlin, Jane E. Harding, Lesley ME McCowan, Michael P. Meyer, Janet A. Rowan, Elaine C. Rush, Christopher JD McKinlay
{"title":"Gestational diabetes detection thresholds and infant growth, nutrition, and neurodevelopment at 12-18 months: a prospective cohort study within a randomized trial","authors":"Francesca Amitrano,&nbsp;Komal Manerkar,&nbsp;Jane M. Alsweiler,&nbsp;Cathryn A. Conlon,&nbsp;Caroline A. Crowther,&nbsp;Richard Edlin,&nbsp;Jane E. Harding,&nbsp;Lesley ME McCowan,&nbsp;Michael P. Meyer,&nbsp;Janet A. Rowan,&nbsp;Elaine C. Rush,&nbsp;Christopher JD McKinlay","doi":"10.1038/s41372-025-02406-x","DOIUrl":"10.1038/s41372-025-02406-x","url":null,"abstract":"To assess the impact of gestational diabetes(GDM) detection thresholds on infant growth, nutrition, and neurodevelopment at 12-18 months. Prospective cohort study within the GEMS trial(ACTRN12615000290594), which randomized pregnant women to detection of GDM using lower or higher glycemic criteria. The main outcomes were overweight/rapid weight gain; food approach appetitive score; energy intake; cognitive z-score. Compared to control infants, those exposed to GDM detected and treated by higher criteria or by lower but not higher criteria that was untreated, were less likely to have increased overweight/rapid weight gain, possibly with lower energy intake. There were no important differences in appetite and cognition. Infants exposed to GDM by lower but not higher criteria that was treated were similar to controls. Exposure to treated GDM or untreated GDM detected by lower but not higher criteria, was not associated with increased infant risk factors for obesity or adverse cognitive outcomes.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":"45 10","pages":"1360-1369"},"PeriodicalIF":2.4,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41372-025-02406-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dexmedetomidine's effect on neonatal sedation, pain, respiratory status and cardiovascular system. 右美托咪定对新生儿镇静、疼痛、呼吸状态和心血管系统的影响。
IF 2.4 3区 医学
Journal of Perinatology Pub Date : 2025-09-04 DOI: 10.1038/s41372-025-02339-5
Marjorie M Makoni, Ivonne Sierra-Strum, Adrianne R Bischoff, Jamie L Miller, Lise DeShea, William Howard Beasley, Edgardo Szyld
{"title":"Dexmedetomidine's effect on neonatal sedation, pain, respiratory status and cardiovascular system.","authors":"Marjorie M Makoni, Ivonne Sierra-Strum, Adrianne R Bischoff, Jamie L Miller, Lise DeShea, William Howard Beasley, Edgardo Szyld","doi":"10.1038/s41372-025-02339-5","DOIUrl":"https://doi.org/10.1038/s41372-025-02339-5","url":null,"abstract":"<p><strong>Objective: </strong>To describe the effects of dexmedetomidine on sedation, pain, respiratory status, and hemodynamics in neonates.</p><p><strong>Methods: </strong>A retrospective study of 206 infants in a level IV NICU (2016-2021) receiving continuous dexmedetomidine infusion. Pain/sedation scores, BP, vasopressor and inotrope score (VIS), and concomitant sedatives/analgesics (CSA) were recorded before and every 3-4 h for 24 h.</p><p><strong>Results: </strong>Median PMA:32 weeks. Hypotension occurred in 26%, primarily in infants <32weeks PMA, correlating with higher VIS and CSA. CSA use significantly predicted vasopressors/inotrope use.</p><p><strong>Conclusion: </strong>Dexmedetomidine, with CSA, increases cardiovascular instability in preterm infants who have unique myocardial structure and function and therefore higher vulnerability.</p><p><strong>Clinical trial registration (if any): </strong>None (not applicable).</p>","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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