Accuracy of lung ultrasound in predicting successful extubation in preterm infants born ≤ 25 weeks.

IF 2.4 3区医学 Q2 OBSTETRICS & GYNECOLOGY

Journal of Perinatology Pub Date : 2025-01-14 DOI:10.1038/s41372-024-02206-9

Haifeng Zong, Bingchun Lin, Yingsui Huang, Yichu Huang, Hongyan Sun, Qingling Xu, Zile Lin, Jiamin Wu, Chuanzhong Yang

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引用次数: 0

Abstract

Objective: The aim of this study was to examine the predictive value of the lung ultrasound score (LUS) for successful extubation in preterm infants born at ≤25⁺⁶ weeks.

Methods: This was a single-center, prospective cohort study. Preterm infants with gestational age (GA) ≤ 25⁺⁶ weeks who received invasive mechanical ventilation (IMV) for ≥72 h were included. Lung ultrasound was performed every day. Multivariate logistic regression analysis was used to evaluate factors that predict extubation outcomes.

Results: Ninety-three infants with GA ≤ 25⁺⁶ weeks were included. The mean GA was 24.5 ± 1.2 weeks. Extubation failure occurred in 55 (59.1%) neonates, and success occurred in 38 (40.9%) neonates. The LUS was significantly lower in the successful group than in the failed group (24.0 ± 2.5 vs. 32.1 ± 3.1 p < 0.001). Logistic regression analysis showed that LUS was an independent predictor of successful extubation (odd ratio 0.15 [95% CI 0.045-0.508], P = 0.002). The area under the receiver operating characteristic curve was 0.98 (p < 0.001) for LUS, and a cutoff value of ≥ 28 had 94.6% sensitivity and 92.7% specificity in detecting extubation failure.

Conclusion: The LUS has good accuracy for predicting successful extubation in extremely preterm infants with GA ≤ 25⁺⁶ weeks.

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肺超声预测≤25周早产儿拔管成功率的准确性。

目的：本研究旨在探讨肺超声评分（LUS）对≤25+6周早产儿拔管成功的预测价值。方法：这是一项单中心、前瞻性队列研究。纳入胎龄(GA)≤25+6周且接受有创机械通气(IMV)≥72 h的早产儿。每天进行肺部超声检查。采用多因素logistic回归分析评价预测拔管结果的因素。结果：纳入GA≤25+6周的患儿93例。平均GA为24.5±1.2周。拔管失败55例（59.1%），成功38例（40.9%）。成功组的LUS明显低于失败组（24.0±2.5∶32.1±3.1 p）。结论：LUS对GA≤25+6周的极早产儿拔管成功有较好的预测准确性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Perinatology 医学-妇产科学

CiteScore

5.40

自引率

6.90%

发文量

284

审稿时长

3-8 weeks

期刊介绍： The Journal of Perinatology provides members of the perinatal/neonatal healthcare team with original information pertinent to improving maternal/fetal and neonatal care. We publish peer-reviewed clinical research articles, state-of-the art reviews, comments, quality improvement reports, and letters to the editor. Articles published in the Journal of Perinatology embrace the full scope of the specialty, including clinical, professional, political, administrative and educational aspects. The Journal also explores legal and ethical issues, neonatal technology and product development. The Journal’s audience includes all those that participate in perinatal/neonatal care, including, but not limited to neonatologists, perinatologists, perinatal epidemiologists, pediatricians and pediatric subspecialists, surgeons, neonatal and perinatal nurses, respiratory therapists, pharmacists, social workers, dieticians, speech and hearing experts, other allied health professionals, as well as subspecialists who participate in patient care including radiologists, laboratory medicine and pathologists.