Journal of Perinatology最新文献

Early exclusive enteral feeding in 30-33 weeks gestation infants: a randomized controlled trial.

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-02-02 DOI: 10.1038/s41372-025-02217-0

Belal N Alshaikh, Ossama Hassan, Wissam Alburaki, Dinesh Dharel, Adel Elsharkawy, Nalini Singal, Kamran Yusuf, Essa Al Awad

{"title":"Early exclusive enteral feeding in 30-33 weeks gestation infants: a randomized controlled trial.","authors":"Belal N Alshaikh, Ossama Hassan, Wissam Alburaki, Dinesh Dharel, Adel Elsharkawy, Nalini Singal, Kamran Yusuf, Essa Al Awad","doi":"10.1038/s41372-025-02217-0","DOIUrl":"https://doi.org/10.1038/s41372-025-02217-0","url":null,"abstract":"Objective: To evaluate feasibility and efficacy of early exclusive enteral feeding (EEEF) in reducing time to achieve full enteral feeds.Methods: A pragmatic randomized controlled trial of infants born at 300/7-336/7 weeks gestation. Infants were randomly assigned to receive EEEF (60-80 mL/kg/day) or conventional feeding (20-30 mL/kg/day) with intravenous fluids after birth. Feed volumes were increased by 20-30 mL/kg/day. Primary outcome was time to reach full enteral feeds.Results: Seventy infants were enrolled. Infants in EEEF group achieved full feeds sooner [Mean difference (MD) -1.2 (95%CI -1.8, -0.7)], required fewer hours of parenteral nutrition [0 (IQR 0, 19) vs. 91 (IQR 48, 132) hours, P < 0.001], had less need for central venous access (11.4% vs. 37.1%, P = 0.01) and had shorter hospital stays [MD -6.6 (95%CI -12.9, -0.2) days].Conclusion: Early exclusive enteral feeding in 300/7-336/7 weeks gestation infants is feasible and reduces time required to achieve full enteral feeds and length of hospital stay.Trial registration: ClinicalTrials.gov: NCT03708068.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neonatology fellow assessment and evaluation: embracing the word salad of CBME, EPAs, and milestones.

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-01-30 DOI: 10.1038/s41372-024-02208-7

Courtney McLean, Beverley Robin, Johannah M Scheurer, Kathryn E K Berlin, Megan M Gray, Deirdre O'Reilly, Heather French, Margarita M Vasquez, Mark Castera, Katherine M Redford, Lindsay C Johnston, Patrick J Myers

引用次数: 0

Changes in the treatment and outcomes of different severities of neonatal hypoxic ischemic encephalopathy in California: a retrospective cohort study.

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-01-26 DOI: 10.1038/s41372-025-02212-5

Carolyn Fall, Rebecca J Baer, Henry C Lee, Gretchen Bandoli, Christina D Chambers

{"title":"Changes in the treatment and outcomes of different severities of neonatal hypoxic ischemic encephalopathy in California: a retrospective cohort study.","authors":"Carolyn Fall, Rebecca J Baer, Henry C Lee, Gretchen Bandoli, Christina D Chambers","doi":"10.1038/s41372-025-02212-5","DOIUrl":"10.1038/s41372-025-02212-5","url":null,"abstract":"Objective: Evaluate the changes in management and outcomes of Californian infants with hypoxic ischemic encephalopathy (HIE).Study design: Infants with HIE were identified from a California administrative birth cohort using ICD codes and divided into two epochs, Epoch 1 (2010-2015) and Epoch 2 (2016-2019). Risk ratios (RR) for induced hypothermia (IH) in each epoch and their outcomes were calculated using log-linear regression.Results: In this cohort, 4779 infants with HIE were identified. Incidence of HIE in California increased yearly from 0.5/1000 California births to a peak of 1.5/1000 births in 2018. The use of IH in infants with mild HIE increased in Epoch 2 compared to Epoch 1. There was no significant difference in outcomes between epochs for infants with mild HIE that received IH including no difference in neonatal seizures.Conclusion: Significantly more infants with mild HIE received IH since 2015 in California, but no significant difference in outcomes.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A systematic review of Perinatal Antibiotic Stewardship - where we are, where to go? 围产期抗生素管理的系统回顾——我们在哪里，往哪里去？

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-01-20 DOI: 10.1038/s41372-025-02209-0

Cristina Winteler, Sara Ardabili, Markus Hodel, Martin Stocker

引用次数: 0

NeoScore: a new tool to assess technical and non-technical skills during neonatal resuscitation. NeoScore：一种评估新生儿复苏过程中技术性和非技术性技能的新工具。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-01-17 DOI: 10.1038/s41372-025-02210-7

Leonardo Meggiolaro, Gary Weiner, Alex Staffler, Fiorenzo Lupi, Tommaso Canesso, Daniele Trevisanuto

{"title":"NeoScore: a new tool to assess technical and non-technical skills during neonatal resuscitation.","authors":"Leonardo Meggiolaro, Gary Weiner, Alex Staffler, Fiorenzo Lupi, Tommaso Canesso, Daniele Trevisanuto","doi":"10.1038/s41372-025-02210-7","DOIUrl":"https://doi.org/10.1038/s41372-025-02210-7","url":null,"abstract":"Background: Training with high-technology manikins improves cardio-pulmonary resuscitation (CPR) skill retention, but a checklist to assess both technical and non-technical skills is lacking. This study aimed to develop a standardized checklist to evaluate healthcare's performance during simulated Neonatal Resuscitation Program (NRP) scenarios.Materials and methods: Twenty-two international neonatal resuscitation experts participated in a two-step modified Delphi process, rating each checklist item on a scale of 1-5 and providing feedback. Items with a mean rating below 4 or receiving comments were reviewed. Inter-rater reliability (IRR) of the final tool was assessed using video-recordings of simulated scenarios.Results: The final checklist, validated by 15 experts, includes 33 items. Mean expert rating of all items was 4.35. The checklist showed moderate inter-rater reliability (ICC = 0.67) overall, with excellent reliability (ICC = 0.8) for technical skills.Conclusion: The tool effectively evaluates technical skills but requires further refinement for non-technical skills assessment.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term feeding outcomes after infant tracheostomy. 婴儿气管切开术后的长期喂养结果。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-01-17 DOI: 10.1038/s41372-024-02205-w

Elena Stekolchik, Md Jobayer Hossain, J Heather Northam, Seema Rani, Abigail Strang, Aaron Chidekel

引用次数: 0

Preterm growth assessment: the latest findings on age correction. 早产儿生长评估：年龄校正的最新发现。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-01-16 DOI: 10.1038/s41372-024-02202-z

Seham Elmrayed, Susan Dai, Abhay Lodha, Manoj Kumar, Tanis R Fenton

引用次数: 0

Accuracy of lung ultrasound in predicting successful extubation in preterm infants born ≤ 25 weeks. 肺超声预测≤25周早产儿拔管成功率的准确性。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-01-14 DOI: 10.1038/s41372-024-02206-9

Haifeng Zong, Bingchun Lin, Yingsui Huang, Yichu Huang, Hongyan Sun, Qingling Xu, Zile Lin, Jiamin Wu, Chuanzhong Yang

{"title":"Accuracy of lung ultrasound in predicting successful extubation in preterm infants born ≤ 25 weeks.","authors":"Haifeng Zong, Bingchun Lin, Yingsui Huang, Yichu Huang, Hongyan Sun, Qingling Xu, Zile Lin, Jiamin Wu, Chuanzhong Yang","doi":"10.1038/s41372-024-02206-9","DOIUrl":"https://doi.org/10.1038/s41372-024-02206-9","url":null,"abstract":"Objective: The aim of this study was to examine the predictive value of the lung ultrasound score (LUS) for successful extubation in preterm infants born at ≤25+6 weeks.Methods: This was a single-center, prospective cohort study. Preterm infants with gestational age (GA) ≤ 25+6 weeks who received invasive mechanical ventilation (IMV) for ≥72 h were included. Lung ultrasound was performed every day. Multivariate logistic regression analysis was used to evaluate factors that predict extubation outcomes.Results: Ninety-three infants with GA ≤ 25+6 weeks were included. The mean GA was 24.5 ± 1.2 weeks. Extubation failure occurred in 55 (59.1%) neonates, and success occurred in 38 (40.9%) neonates. The LUS was significantly lower in the successful group than in the failed group (24.0 ± 2.5 vs. 32.1 ± 3.1 p < 0.001). Logistic regression analysis showed that LUS was an independent predictor of successful extubation (odd ratio 0.15 [95% CI 0.045-0.508], P = 0.002). The area under the receiver operating characteristic curve was 0.98 (p < 0.001) for LUS, and a cutoff value of ≥ 28 had 94.6% sensitivity and 92.7% specificity in detecting extubation failure.Conclusion: The LUS has good accuracy for predicting successful extubation in extremely preterm infants with GA ≤ 25+6 weeks.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142983446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Meta-analysis and Mendelian randomization study on the association between exposure to chlorinated disinfection byproducts and preterm birth risk. 氯化消毒副产物暴露与早产风险关系的荟萃分析和孟德尔随机化研究。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-01-09 DOI: 10.1038/s41372-024-02195-9

Changxia Cheng, Yanling Pei, Guangyu Shan, Yutao Liu

{"title":"Meta-analysis and Mendelian randomization study on the association between exposure to chlorinated disinfection byproducts and preterm birth risk.","authors":"Changxia Cheng, Yanling Pei, Guangyu Shan, Yutao Liu","doi":"10.1038/s41372-024-02195-9","DOIUrl":"https://doi.org/10.1038/s41372-024-02195-9","url":null,"abstract":"Objective: This study aims to investigate the correlation between exposure to disinfection byproducts of chlorination and preterm birth (PTB) through evidence-based medicine Meta-analysis and Mendelian randomization (MR) analysis.Study design: Meta-analysis was conducted on 17 studies involving 1,251,426 neonates, revealing a higher risk of PTB with exposure to total trihalomethanes (TTHMs) and chloroform. Mendelian randomization (MR) analysis confirmed a causal relationship between chlorides and PTB.Results: TTHMs and chloroform were associated with increased PTB risk, while haloacetic acids showed no significant association. TTHMs were linked to small gestational age. Ethnicity and study design influenced heterogeneity.Conclusions: Exposure to chlorination byproducts, particularly TTHMs and chloroform, poses a significant risk for PTB. MR analysis supports a causal relationship between chlorides and PTB, highlighting the importance of water disinfection byproduct control in preventing PTB.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of unplanned extubations and neurodevelopmental outcomes in very low birthweight infants. 极低出生体重儿意外拔管与神经发育结局的关系。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2024-12-28 DOI: 10.1038/s41372-024-02203-y

Alexandra Golden, Mary Lauren Neel, Rachel Goode, M Wael Alrifai, L Dupree Hatch

引用次数: 0