Journal of Perinatology最新文献_第10页

Differences in practices for surgical site infection prevention in neonatal surgery between neonatologists and pediatric surgeons: a multicenter survey in Japan. 在新生儿外科手术中，新生儿医生和儿科医生手术部位感染预防的实践差异：日本的一项多中心调查。

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-07-30 DOI: 10.1038/s41372-026-02803-w

Tomohiro Sunouchi, Jun Fujishiro, Toru Higuchi, Hiroki Sakurai, Akihiko Shimizu, Sho Ishii, Taizo Kusano, Yuho Horikoshi, Yoshiaki Shikama, Takemi Murai, Takayo Shoji, Kenta Ito, Masatoshi Nozaki, Shinsuke Mizuno, Takafumi Okada, Takayuki Hoshina, Yoshiaki Cho, Yoshie Sakurai, Hisao Okabe, Daisuke Tamura, Yuki Muta, Chizuka Seki, Ryu Yoneda, Naho Fujiwara, Masayoshi Shinjoh, Tomohiro Katsuta, Koo Nagasawa, Toshihiko Okumura, Hiroki Miura, Yoshiki Kusama, Kazumichi Fujioka, Yoshitomo Motomura, Yoshihiro Takahashi, Chikara Ogimi

{"title":"Differences in practices for surgical site infection prevention in neonatal surgery between neonatologists and pediatric surgeons: a multicenter survey in Japan.","authors":"Tomohiro Sunouchi, Jun Fujishiro, Toru Higuchi, Hiroki Sakurai, Akihiko Shimizu, Sho Ishii, Taizo Kusano, Yuho Horikoshi, Yoshiaki Shikama, Takemi Murai, Takayo Shoji, Kenta Ito, Masatoshi Nozaki, Shinsuke Mizuno, Takafumi Okada, Takayuki Hoshina, Yoshiaki Cho, Yoshie Sakurai, Hisao Okabe, Daisuke Tamura, Yuki Muta, Chizuka Seki, Ryu Yoneda, Naho Fujiwara, Masayoshi Shinjoh, Tomohiro Katsuta, Koo Nagasawa, Toshihiko Okumura, Hiroki Miura, Yoshiki Kusama, Kazumichi Fujioka, Yoshitomo Motomura, Yoshihiro Takahashi, Chikara Ogimi","doi":"10.1038/s41372-026-02803-w","DOIUrl":"https://doi.org/10.1038/s41372-026-02803-w","url":null,"abstract":"Objective: To assess the current surgical site infection prevention practices in neonatal surgery, especially focusing on the factors that determine the duration of perioperative antibiotic prophylaxis (PAP) and the differences between pediatric surgeons and neonatologists.Study design: We performed a questionnaire survey, which targeted neonatologists, pediatric surgeons, and infectious disease specialists at pediatric hospitals or university hospitals in Japan.Results: Responses were obtained from 32 hospitals. Some practices, such as criteria for discontinuing PAP, intraoperative re-administration of PAP, and preoperative decontamination of methicillin-resistant Staphylococcus aureus, were different between neonatologists and pediatric surgeons. Regarding criteria for discontinuing PAP, pediatric surgeons tended to select \"fixed duration\", while neonatologists more often relied on \"C-reactive protein levels.\"Conclusion: PAP discontinuation practices in neonatal surgery reflect distinct time-based and biomarker-guided decision-making approaches between pediatric surgeons and neonatologists, indicating the need for clearer evidence and consensus. More standardized, evidence-based approaches are required.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148630812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Associations between opioid exposure and brain size among extremely preterm infants. 极早产儿阿片类药物暴露与大脑大小之间的关系。

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-07-30 DOI: 10.1038/s41372-026-02847-y

Seh Hyun Kim, Sara Cherkerzian, Yvonne Sheldon, Katherine Bell, Kaitlyn Roddy, Sara E Rostas, Debra Marks, Tina Steele, Elizabeth Singh, Kirsten Thiim, Aisling Garvey, Mohamed El-Dib, Terrie Inder

{"title":"Associations between opioid exposure and brain size among extremely preterm infants.","authors":"Seh Hyun Kim, Sara Cherkerzian, Yvonne Sheldon, Katherine Bell, Kaitlyn Roddy, Sara E Rostas, Debra Marks, Tina Steele, Elizabeth Singh, Kirsten Thiim, Aisling Garvey, Mohamed El-Dib, Terrie Inder","doi":"10.1038/s41372-026-02847-y","DOIUrl":"https://doi.org/10.1038/s41372-026-02847-y","url":null,"abstract":"Objective: Morphine and fentanyl are commonly used drugs in extremely preterm infants in the neonatal intensive care unit (NICU), but their impact on brain growth is unclear. This study aimed to evaluate the relationship between opioid exposure and brain size in extremely preterm infants.Study design: This is a retrospective cohort study of preterm infants born less than 28 weeks gestation who received opioids and underwent term-equivalent brain magnetic resonance imaging. Brain size was assessed using corrected biparietal width (cBPW) and corrected transcerebellar diameter (cTCD).Result: This study included 51 preterm infants. Multivariable linear mixed model analysis adjusted for gestational age and birthweight Z-score showed increased natural log opioid duration was associated with lower mean cTCD (β: -0.99, 95% CI -1.94, -0.05).Conclusion: Longer duration of opioid exposure in the NICU was associated with smaller cerebellar size at term equivalent age.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148630835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CAKUT calculator: a clinical risk prediction tool for in-hospital mortality in neonates with congenital anomalies of the kidney and urinary tract admitted to level IV NICUs. CAKUT计算器：一种临床风险预测工具，用于IV级新生儿重症监护病房中患有先天性肾脏和尿路异常的新生儿的住院死亡率。

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-07-30 DOI: 10.1038/s41372-026-02823-6

Jennifer A Rumpel, Isabella Zaniletti, Christine Stoops, Courtney P Verscaj, Matthew W Harer, Andrew M South, Catherine Joseph, Semsa Gogcu, Mary Revenis, Mona Khattab, Michael Padula, Theresa Grover, Karna Murthy, Sofia I Perazzo

{"title":"CAKUT calculator: a clinical risk prediction tool for in-hospital mortality in neonates with congenital anomalies of the kidney and urinary tract admitted to level IV NICUs.","authors":"Jennifer A Rumpel, Isabella Zaniletti, Christine Stoops, Courtney P Verscaj, Matthew W Harer, Andrew M South, Catherine Joseph, Semsa Gogcu, Mary Revenis, Mona Khattab, Michael Padula, Theresa Grover, Karna Murthy, Sofia I Perazzo","doi":"10.1038/s41372-026-02823-6","DOIUrl":"10.1038/s41372-026-02823-6","url":null,"abstract":"Objective: To predict in-hospital mortality for infants with congenital anomalies of the kidney and urinary tract (CAKUT) using perinatal factors and use the resultant model to create an interactive clinical risk calculator.Study design: A retrospective cohort study included 13,233 neonates with CAKUT diagnoses admitted to forty-six level IV neonatal intensive care units participating in the Children's Hospitals Neonatal Consortium from 2010 to 2024. A predictive model for in-hospital mortality was built using perinatal risk factors.Results: 1353 (10.2%) neonates died. Eight perinatal factors predicted mortality with strong model performance (area under the curve: 0.87 (95% confidence interval [CI]: 0.85, 0.88) training; 0.84 (95% CI: 0.82, 0.86) validation).Conclusion: For newborn infants with CAKUT, prediction of in-hospital mortality can be estimated using 8 factors identifiable during the immediate perinatal period. Correspondingly, an on-line calculator that is publicly available for clinicians, researchers, and families of affected infants can be integrated in perinatal management.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148630847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neonatal transport for convalescing infants: occurrence and barriers reported by providers. 康复婴儿的新生儿转运：提供者报告的发生和障碍。

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-07-30 DOI: 10.1038/s41372-026-02833-4

Lindsay S Womack-Martenson, Susan E Manning, Angela Rohan, Lisa Romero, Shanna Cox, Wanda D Barfield, Charlan D Kroelinger

引用次数: 0

Automated oxygen control versus manual titration in preterm infants: A systematic review and meta-analysis. 早产儿自动氧控制与人工滴定：一项系统综述和荟萃分析。

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-07-30 DOI: 10.1038/s41372-026-02842-3

Mohammad Amouri, Salahaldeen Deeb, Nouraldeen Deeb, Ayshe M Zoabi, Alhareth M Amro, Ahmed Rayyan, Motee Abuawwad

{"title":"Automated oxygen control versus manual titration in preterm infants: A systematic review and meta-analysis.","authors":"Mohammad Amouri, Salahaldeen Deeb, Nouraldeen Deeb, Ayshe M Zoabi, Alhareth M Amro, Ahmed Rayyan, Motee Abuawwad","doi":"10.1038/s41372-026-02842-3","DOIUrl":"https://doi.org/10.1038/s41372-026-02842-3","url":null,"abstract":"Objective: To evaluate whether closed-loop automated fraction of inspired oxygen (FiO2) control improves oxygen targeting and clinical outcomes compared with clinician-directed manual titration in preterm infants.Study design: Systematic review and random-effects meta-analysis of randomized trials searched through Feb 6, 2026. Crossover and parallel-group trials informed physiological outcomes; only longitudinal parallel-group trials informed clinical outcomes.Results: Twenty-three trials (1777 infants) were included. Automated control increased time within target range (mean difference 15.01 percentage points, 95% CI 10.90 to 19.13) and reduced time above target, below target, SpO2 < 80%, SpO2 > 98%, and manual FiO2 adjustments. Clinical outcomes remained uncertain: bronchopulmonary dysplasia risk ratio 0.80, death 1.03, necrotizing enterocolitis 0.81, and treatment-requiring retinopathy of prematurity 0.90.Conclusion: Automated FiO2 control consistently improves oxygen targeting, but current randomized evidence does not show clear benefit for major neonatal outcomes.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148630825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prenatal biometry-based prediction of optimal endotracheal tube depth in infants with a birth weight less than 500 g. 出生体重小于500g婴儿最佳气管插管深度的产前生物统计学预测。

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-07-29 DOI: 10.1038/s41372-026-02851-2

Kyusang Yoo, Soo Hyun Kim, Juhee Park, Tae-Gyeong Kim, Jung Il Kwak, Jeong Min Lee, Ha Na Lee, Jiyoon Jeong, Chae Young Kim, Mi-Young Lee, Euiseok Jung, Jin Hoon Chung, Byong Sop Lee, Hye-Sung Won

{"title":"Prenatal biometry-based prediction of optimal endotracheal tube depth in infants with a birth weight less than 500 g.","authors":"Kyusang Yoo, Soo Hyun Kim, Juhee Park, Tae-Gyeong Kim, Jung Il Kwak, Jeong Min Lee, Ha Na Lee, Jiyoon Jeong, Chae Young Kim, Mi-Young Lee, Euiseok Jung, Jin Hoon Chung, Byong Sop Lee, Hye-Sung Won","doi":"10.1038/s41372-026-02851-2","DOIUrl":"https://doi.org/10.1038/s41372-026-02851-2","url":null,"abstract":"Objective: To develop a prenatal biometry-based model predicting optimal oral endotracheal tube (ETT) depth in infants with birth weight <500 g.Study design: Retrospective single-center cohort of 62 infants (birth weight <500 g) orally intubated at birth, with prenatal ultrasound within 3 days of delivery. Optimal ETT depth was determined from post-intubation radiographs. Femur length (FL), estimated fetal weight (EFW), biparietal diameter, head circumference, and abdominal circumference were assessed by correlation and multivariable regression.Results: Gestational age was 25.2 ± 1.7 weeks; birth weight, 437 g (382.5-470 g). Malposition ≥0.5 cm occurred in 29 infants (46.8%). FL and EFW correlated strongly with optimal depth (r = 0.598 and 0.594; both p < 0.001). The quadratic model combining FL and EFW yielded the best fit (adjusted R² = 0.58).Conclusion: Prenatal FL and EFW may guide predelivery oral ETT depth in infants with birth weight <500 g, supporting individualized airway planning.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148620464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Silent struggles of internalizing disorders in survivors of neonatal hypoxic ischemic encephalopathy: a scoping review. 新生儿缺氧缺血性脑病幸存者内化障碍的沉默斗争：范围审查。

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-07-29 DOI: 10.1038/s41372-026-02834-3

Nursena Yabalar, Irem Isik, Nur Aycan, Mary Hitchcock, Sarah Elizabeth Nigro, Alanna M Kessler-Jones, Pelin Cengiz, Jonathan J Mietchen

{"title":"Silent struggles of internalizing disorders in survivors of neonatal hypoxic ischemic encephalopathy: a scoping review.","authors":"Nursena Yabalar, Irem Isik, Nur Aycan, Mary Hitchcock, Sarah Elizabeth Nigro, Alanna M Kessler-Jones, Pelin Cengiz, Jonathan J Mietchen","doi":"10.1038/s41372-026-02834-3","DOIUrl":"10.1038/s41372-026-02834-3","url":null,"abstract":"Internalizing disorders in children and adolescents include anxiety, depression, and somatic symptoms. Early identification is essential to prevent long-term mental health challenges. Hypoxic-ischemic encephalopathy (HIE) has been associated with an increased risk of internalizing disorders in early life. This scoping review summarized the literature on internalizing disorders in HIE survivors, highlighting the assessment methods and psychological outcomes. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for scoping reviews and included peer-reviewed studies reporting internalizing symptoms in HIE survivors. Five major databases were searched, and study quality was assessed using the Newcastle-Ottawa Scale. Of the 2917 studies screened, twelve met the inclusion criteria. Our review revealed variability in internalizing symptoms, but nine of the 12 studies showed that HIE survivors had higher internalizing symptoms. This review revealed substantial variability across studies, underscoring the need for more standardized assessment tools and early screening during early childhood.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148620509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of ocean sounds played during retinopathy of prematurity examinations on physiology, pain, and comfort levels: a randomized controlled trial. 早产儿视网膜病变检查期间播放海洋声音对生理、疼痛和舒适度的影响：一项随机对照试验。

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-07-29 DOI: 10.1038/s41372-026-02839-y

Gülay Arslan, Emine Geçkil, Günhal Şatırtav Akdeniz, Hüseyin Altunhan

{"title":"Effect of ocean sounds played during retinopathy of prematurity examinations on physiology, pain, and comfort levels: a randomized controlled trial.","authors":"Gülay Arslan, Emine Geçkil, Günhal Şatırtav Akdeniz, Hüseyin Altunhan","doi":"10.1038/s41372-026-02839-y","DOIUrl":"https://doi.org/10.1038/s41372-026-02839-y","url":null,"abstract":"Objective: This study aimed to determine the effect of ocean sounds played during ROP examinations on pain, comfort, and physiological parameters of premature infants.Study design: In the randomized controlled trial, 44 premature infants were included in the study via stratified randomization. In the intervention group, ocean sounds were played starting 1 min before and until 5 min after the ROP examination. No sound was played for the control group. The examinations were recorded on video and evaluated by independent observers who were blinded to the study.Results: There was no statistically significant difference in the pain levels and mean comfort scores between the two groups at 1 and 5 min after the procedure. Stabilization was achieved in both groups in heart rate and oxygen saturation; however, the difference between the groups was not significant.Conclusions: Ocean sounds alone had no significant effect on pain, comfort or physiological parameters during ROP examinations.Clinical trial registration: The protocol for this randomized controlled experimental trial is registered on ClinicalTrials.gov. The clinical trial registration number is https://clinicaltrials.gov ; NCT05203159.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148620558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of a comprehensive BPD follow-up clinic on one-year outcomes of patients with bronchopulmonary dysplasia discharged on home supplemental oxygen therapy. 全面BPD随访临床对支气管肺发育不良患者出院后家庭辅助氧疗一年预后的影响

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-07-29 DOI: 10.1038/s41372-026-02843-2

Christine Sugimoto, Jennifer M Brady, Erik Hysinger, Melissa Kingma, Melissa House

{"title":"Influence of a comprehensive BPD follow-up clinic on one-year outcomes of patients with bronchopulmonary dysplasia discharged on home supplemental oxygen therapy.","authors":"Christine Sugimoto, Jennifer M Brady, Erik Hysinger, Melissa Kingma, Melissa House","doi":"10.1038/s41372-026-02843-2","DOIUrl":"https://doi.org/10.1038/s41372-026-02843-2","url":null,"abstract":"Objective: Infants with bronchopulmonary dysplasia (BPD) discharged on supplemental oxygen have complex care needs after discharge. This study explored the impact of a comprehensive BPD clinic on respiratory and growth outcomes, resource utilization, and healthcare expenditures for patients with BPD discharged home on oxygen.Study design: We performed a retrospective study of 86 infants with moderate or severe BPD discharged on supplemental oxygen who were followed in a routine neonatal follow-up clinic or in a comprehensive BPD clinic with neonatology and pulmonary services. Outcomes were compared using univariate analyses.Results: Despite the higher complexity of the patients in the comprehensive clinic group, there were fewer unplanned non-ICU admissions and respiratory-related readmissions compared to patients in the neonatal follow-up group. The median number of emergency department visits and total healthcare expenditures were similar between groups.Conclusions: Comprehensive follow-up reduces readmissions without increasing healthcare costs for infants with BPD discharged home on supplemental oxygen.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148620546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feasibility of lung ultrasound-guided positive end-expiratory pressure adjustment in newborns. 超声引导下新生儿肺呼气末正压调节的可行性。

IF 2.3 3区医学

Journal of Perinatology Pub Date : 2026-07-28 DOI: 10.1038/s41372-026-02831-6

Anna Holst Møller, Christian Heiring, Sebastian Pornpakdee Feldskou, Katrin Klebermass-Schrehof, Mette Høj Lauridsen, Kasper Jacobsen Kyng

{"title":"Feasibility of lung ultrasound-guided positive end-expiratory pressure adjustment in newborns.","authors":"Anna Holst Møller, Christian Heiring, Sebastian Pornpakdee Feldskou, Katrin Klebermass-Schrehof, Mette Høj Lauridsen, Kasper Jacobsen Kyng","doi":"10.1038/s41372-026-02831-6","DOIUrl":"https://doi.org/10.1038/s41372-026-02831-6","url":null,"abstract":"Objective: To evaluate whether an ultrasound-guided lung recruitment manoeuvre (LRM) can identify a positive end-expiratory pressure (PEEP) associated with improved aeration compared with clinically set PEEP during non-invasive respiratory support.Study design: Feasibility study of 11 spontaneously breathing infants on continuous positive airway pressure or non-invasive ventilation. PEEP was increased stepwise by 2 cmH2O from 4 to 10 cmH2O. The PEEP with the lowest lung ultrasound score was recorded along with vital parameters.Results: In 10 of 11 infants (91%; 95% confidence interval 62-99, p = 0.01), the LRM identified a PEEP with a lower lung ultrasound score than the clinically set level; five infants required a higher and five a lower PEEP. Clinical parameters were stable or improved.Conclusion: In this pilot cohort, lung ultrasound-guided PEEP adjustment appeared feasible and was associated with favourable short-term changes in lung aeration. Larger studies are required to validate these preliminary findings and determine clinical utility.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148604255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0