Journal of Perinatology最新文献_第10页

Preterm Premature Rupture of Membranes (PPROM) and Neurodevelopmental Outcomes 早产胎膜早破（PPROM）和神经发育结局。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-07-18 DOI: 10.1038/s41372-025-02360-8

H. Bhullar, A. Stritzke, S. Makarchuk, S. Tang, A. Lodha

引用次数: 0

Less invasive surfactant administration in the delivery room: A quality improvement initiative. 产房中微创表面活性剂的使用：一项质量改进倡议。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-07-10 DOI: 10.1038/s41372-025-02350-w

Jonathan R Burris, Blair F Germain, Patricia R Chess, Elizabeth A Powers, Rebecca Gillis, Hyacinth G Lewis, Jamey Tulloch, Colby L Day, Andrew M Dylag

{"title":"Less invasive surfactant administration in the delivery room: A quality improvement initiative.","authors":"Jonathan R Burris, Blair F Germain, Patricia R Chess, Elizabeth A Powers, Rebecca Gillis, Hyacinth G Lewis, Jamey Tulloch, Colby L Day, Andrew M Dylag","doi":"10.1038/s41372-025-02350-w","DOIUrl":"https://doi.org/10.1038/s41372-025-02350-w","url":null,"abstract":"Objective: To evaluate less invasive surfactant administration (LISA) in the delivery room as a part of neonatal stabilization and reduce infants requiring intubation.Project design: A SMART aim was developed to implement LISA in >30% of infants (25.0-31.6 weeks' gestational age) with respiratory distress syndrome (RDS) in the NICU or delivery room (DR) and increase the number of infants never requiring intubation by 50% by 12/31/2023. Three sequential Plan-Do-Study-Act cycles were implemented. Statistical Process Control charts tracked time-ordered data.Results: Over 4 years, 184 patients received LISA (N = 112 in the DR). LISA was safe and successful (98.9%), including DR. DR intubations were reduced (65.5 to 52.6%), infants never requiring intubation increased (22.8 to 38%), and Grade 2 or 3 BPD (12.9 to 8.8%) was reduced.Conclusion: LISA in the delivery room is safe and effective for RDS and associated with reduced need for intubation, mechanical ventilation, and BPD.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144608623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An improvement project standardizing low prophylactic platelet transfusion dosing for infants. 婴儿预防性血小板输注低剂量标准化改进项目。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-07-09 DOI: 10.1038/s41372-025-02347-5

Kristen Coletti, Jennifer A Hershey, Matthew Devine, Jennifer Taft, Jeff Schinella, Sekinah Ajiboye, Kathleen Gibbs, Michele P Lambert, David Friedman, Christopher S Thom

{"title":"An improvement project standardizing low prophylactic platelet transfusion dosing for infants.","authors":"Kristen Coletti, Jennifer A Hershey, Matthew Devine, Jennifer Taft, Jeff Schinella, Sekinah Ajiboye, Kathleen Gibbs, Michele P Lambert, David Friedman, Christopher S Thom","doi":"10.1038/s41372-025-02347-5","DOIUrl":"https://doi.org/10.1038/s41372-025-02347-5","url":null,"abstract":"Background: Platelet transfusions are frequently given to preterm infants to prevent bleeding, but randomized trials demonstrated harmful effects from current practices.Problem: Many platelet transfusions were administered in 15-20 mL/kg doses.Methods: We sought to decrease platelet exposure among neonates by standardizing 10 mL/kg transfusions for non-bleeding thrombocytopenic infants in a level IV NICU.Interventions: We created evidence-based platelet dosing guidelines and changed practices in 3 plan-do-study-act cycles focused on education, reinforcement and electronic clinical decision support.Results: We reviewed 240 transfusions over 3 years. The percentage of 10 mL/kg transfusions improved from 17.6% to 100%, without increasing major bleeding and repeat transfusion rates. Monthly transfused platelet volumes decreased from 2269 ± 334 mL to 857 ± 181 mL (p < 0.001), conserving limited platelet resources and saving $2746-$4942 per month in platelets.Conclusions: This study improved our platelet transfusion practices and can facilitate similar transfusion guideline adoption to benefit neonates at other institutions.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictive model of ibuprofen treatment failure in very preterm infants with patent ductus arteriosus using machine learning techniques 利用机器学习技术预测动脉导管未闭早产儿布洛芬治疗失败的模型。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-07-08 DOI: 10.1038/s41372-025-02346-6

María Carmen Bravo, Emilio Parrado-Hernández, Patrick J. McNamara, Adelina Pellicer

引用次数: 0

Association of low hospital birth volume and adverse short-term outcomes for neonates treated with therapeutic hypothermia in rural states. 低住院产生量与农村地区接受治疗性低温治疗的新生儿不良短期结局的关系

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-07-06 DOI: 10.1038/s41372-025-02352-8

Alexa K Craig, Anya Cutler, Jay Kerecman, Misty Melendi, Leah Marie Seften, Matthew Ryzewski, Allison Zanno, Deirdre O'Reilly

{"title":"Association of low hospital birth volume and adverse short-term outcomes for neonates treated with therapeutic hypothermia in rural states.","authors":"Alexa K Craig, Anya Cutler, Jay Kerecman, Misty Melendi, Leah Marie Seften, Matthew Ryzewski, Allison Zanno, Deirdre O'Reilly","doi":"10.1038/s41372-025-02352-8","DOIUrl":"10.1038/s41372-025-02352-8","url":null,"abstract":"Objective: We hypothesized that outborn neonates in three rural states would have more frequent adverse short-term outcomes following therapeutic hypothermia (TH).Study design: Multicenter retrospective study comparing outcomes for low (<500 births/year), medium (501-1500 births/year), and high (>1500 births/year) birth volume hospitals in Northern New England. Multivariable logistic regression assessed the combined outcome of death/severe gray matter injury on MRI, controlling for encephalopathy severity and time to initiation of TH.Results: Death occurred for 35/531 neonates: 15/120 (12%) low, 7/193 (4%) medium, and 13/218 (6%) for high birth volume hospitals (p = 0.008). Severe gray matter injury occurred in 8%, 6% and 7% of low, medium, and high birth volume hospitals, respectively (p = 0.7). Odds of the combined outcome were 4.3-fold higher in low versus high volume hospitals (95% CI = 1.6, 12.1, p = 0.004).Conclusion: Neonates born in low volume birth hospitals had significantly higher odds of death following treatment with TH.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nurse and parent perspectives of a neonatal intensive care unit redesign from open-bay to single-family rooms 新生儿重症监护室从开舱到单户病房的重新设计的护士和家长视角。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-07-03 DOI: 10.1038/s41372-025-02342-w

Stephanie M. Teixeira-Poit, Bonnie Fields, Marjorie Jenkins, Susan Jones, Candace Matthews, Vannessa Gharbi, Serena Lowe, Frances A. Kendrick, sal ryman, Raven Funderburk

{"title":"Nurse and parent perspectives of a neonatal intensive care unit redesign from open-bay to single-family rooms","authors":"Stephanie M. Teixeira-Poit, Bonnie Fields, Marjorie Jenkins, Susan Jones, Candace Matthews, Vannessa Gharbi, Serena Lowe, Frances A. Kendrick, sal ryman, Raven Funderburk","doi":"10.1038/s41372-025-02342-w","DOIUrl":"10.1038/s41372-025-02342-w","url":null,"abstract":"To assess nurse and parent perspectives of a neonatal intensive care unit (NICU) redesign from open-bay (OPBY) to single-family rooms (SFR). We analyze interviews with NICU nurses and surveys with parents/guardians of neonates discharged from the NICU in the OPBY compared to SFR settings. The SFR design increased privacy, eased facilitation of sterile and isolation procedures, and improved perceived comfort of parent participation in breastfeeding and kangaroo, or skin-to-skin, care. Increased privacy in the SFR design also resulted in unintended consequences including limited visibility of the healthcare team and increased need for clinician-parent communication. Policies and procedures meant to keep families safe during COVID-19 further decreased parents’ perceived access to and responsiveness of the healthcare team. Supportive policies and procedures promoting increased clinician-parent communication and additional parental supports may need to accompany transitions to SFRs to realize improvements in parental assessments of quality of care.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":"45 6","pages":"851-856"},"PeriodicalIF":2.4,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12263430/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144560447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postnatal dexamethasone for infants on chronic non-invasive positive pressure ventilation. 产后地塞米松对慢性无创正压通气婴儿的影响。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-07-02 DOI: 10.1038/s41372-025-02344-8

Priya Tiwari, Jaslynn Radford, Michael Norberg, Alain Cuna

引用次数: 0

Drivers of care and outcomes for people facing fetal conditions in the United States: a conceptual framework 美国面临胎儿状况的人的护理和结果的驱动因素：一个概念框架。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-07-02 DOI: 10.1038/s41372-025-02340-y

Abigail B. Wilpers, Scott A. Lorch

{"title":"Drivers of care and outcomes for people facing fetal conditions in the United States: a conceptual framework","authors":"Abigail B. Wilpers, Scott A. Lorch","doi":"10.1038/s41372-025-02340-y","DOIUrl":"10.1038/s41372-025-02340-y","url":null,"abstract":"Congenital anomalies, affecting 3–5% of pregnancies annually in the United States, are a leading cause of fetal and infant mortality. Despite advancements in fetal care, disparities in care access, quality, and outcomes persist and remain poorly understood. This perspective introduces the Fetal Condition Care and Outcomes (FCCO) Framework, a conceptual model that integrates contextual, individual, structural, and process-level factors influencing care and outcomes. We build on prior adaptations of Andersen’s Behavioral Model of Health Service Use and the Donabedian Structure, Process, and Outcomes Model, expanding their application from risk-appropriate neonatal care to individuals’ whose pregnancies are complicated by severe fetal conditions. By synthesizing evidence across disciplines, we highlight critical gaps in understanding the drivers of disparities, including barriers to timely diagnosis, variations in counseling practices, and inequities in access to specialized services. This article calls for interdisciplinary research to ensure risk-appropriate, person-centered care for this high-risk population.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":"45 9","pages":"1311-1317"},"PeriodicalIF":2.4,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12431852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Disposable pressure transducer to identify central pressure measurements in umbilical lines for preterm and term infants in the neonatal intensive care unit 一次性压力传感器用于识别新生儿重症监护病房早产儿和足月婴儿脐带线上的中心压力测量。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-07-02 DOI: 10.1038/s41372-025-02338-6

Carrie Moore, Lori A. Devlin, Cynthia Crabtree, Amanda Farris, Joshua Kurtz, Keri Marques

{"title":"Disposable pressure transducer to identify central pressure measurements in umbilical lines for preterm and term infants in the neonatal intensive care unit","authors":"Carrie Moore, Lori A. Devlin, Cynthia Crabtree, Amanda Farris, Joshua Kurtz, Keri Marques","doi":"10.1038/s41372-025-02338-6","DOIUrl":"10.1038/s41372-025-02338-6","url":null,"abstract":"Assess the feasibility of using a disposable pressure transducer with integrated digital display to differentiate arterial versus venous line placement in neonates. Infants ≥23 weeks’ gestation with appropriately placed umbilical catheters were enrolled. A single baseline pressure reading was obtained, hypothesizing that arterial placement could be differentiated with a pressure ≥12 mmHg. Forty-five infants were enrolled to obtain 62 measurements, 31 from both umbilical artery catheters(UAC) and umbilical venous catheters(UVC). 100% of UAC were ≥12 mmHg and 87% of UVC were <12 mmHg. Median device pressures for UAC and UVC were 41 mmHg (IQR 31–45 mmHg) and 5 mmHg (IQR 3–9 mmHg) (p-value < 0.0001). An optimal venous device pressure cut point was determined to be 21 mmHG (97% sensitivity, 100% specificity, AUC 0.98). This transducer is likely safe and can differentiate line placement in arterial and venous systems. 12 mmHg appears to reliably identify lines placed in the arterial system, but 21 mmHG was found to be the optimal venous cut point.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":"45 10","pages":"1389-1394"},"PeriodicalIF":2.4,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structured pre-delivery huddles enhance confidence in managing newborns with critical congenital heart disease in the delivery room. 结构化的产前会议提高了在产房管理新生儿重症先天性心脏病的信心。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-07-01 Epub Date: 2024-12-10 DOI: 10.1038/s41372-024-02196-8

Alyssa R Thomas, Caitlin Bowen, Elisa Abdulhayoglu, Elizabeth Brennick, Kendra Woo, Margaret F Everett, Eleonore Valencia, Kristen T Leeman, Simon M Manning, Elisabeth Kaza

{"title":"Structured pre-delivery huddles enhance confidence in managing newborns with critical congenital heart disease in the delivery room.","authors":"Alyssa R Thomas, Caitlin Bowen, Elisa Abdulhayoglu, Elizabeth Brennick, Kendra Woo, Margaret F Everett, Eleonore Valencia, Kristen T Leeman, Simon M Manning, Elisabeth Kaza","doi":"10.1038/s41372-024-02196-8","DOIUrl":"10.1038/s41372-024-02196-8","url":null,"abstract":"Background: Newborns with critical congenital heart disease (CCHD) require specialized delivery room management, but varying experience and knowledge can reduce confidence and impact care.Methods: A pre-delivery, structured huddle checklist was introduced, addressing team roles, expected physiology, and management plans. PDSA cycles incorporated guidelines and simulation-based education to improve confidence in specialized resuscitation strategies. Surveys were conducted at baseline and 6 months.Results: Baseline, all-respondent confidence in managing \"all types of CCHD\" was somewhat confident (median 3/5; IQR 2-4) increasing to moderately confident (4/5; IQR 2-4) at 6 months (p = 0.59). Respondents with 0-3 years' experience showed increased confidence over 6 months in identifying unstable infants (from baseline 24% to 67% moderately/very confident, p = 0.005), prostaglandin E1 needs (from 24% to 62%, p = 0.013) and sedation requirements (from 5% to 33%, p = 0.045).Conclusion: Structured huddles improved confidence among less experienced team members, emphasizing the importance of shared mental models before CCHD deliveries.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":"1009-1016"},"PeriodicalIF":2.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0