Journal of Perinatology最新文献_第10页

Are racial and ethnic disparities in brachial plexus birth injuries explained by known risk factors? 臂丛出生损伤的种族差异是否可以用已知的危险因素来解释？

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-03-15 DOI: 10.1038/s41372-025-02239-8

M Claire Manske, Machelle D Wilson, Barton L Wise, Herman L Hedriana, Joy Melnikow, Daniel J Tancredi

{"title":"Are racial and ethnic disparities in brachial plexus birth injuries explained by known risk factors?","authors":"M Claire Manske, Machelle D Wilson, Barton L Wise, Herman L Hedriana, Joy Melnikow, Daniel J Tancredi","doi":"10.1038/s41372-025-02239-8","DOIUrl":"10.1038/s41372-025-02239-8","url":null,"abstract":"Objective: To investigate the association of maternal race/ethnicity with risk factors for brachial plexus birth injury (BPBI) and quantify the proportion of excess BPBI risk due to these factors.Study design: This retrospective cohort study of all livebirths occurring in California-licensed hospitals from 1996-2012 included 6,278,562 maternal-livebirth infant pairs with 7762 BPBI diagnoses. Multiple logistic regression and causal mediation analyses were used to evaluate the relationship of race/ethnicity and BPBI risk factors.Results: Black and Hispanic birthing-individuals were at increased risk of obesity, diabetes, and limited prenatal care utilization but decreased risk of many BPBI risk factors (shoulder dystocia, macrosomia, prolonged second stage of labor, and vaginal delivery).Conclusions: Black and Hispanic birthing-individuals were at lower risk of many strongly associated risk factors for BPBI, and these factors mediate only a small proportion of their excess BPBI risk, underscoring the importance of identifying alternative risk factors, especially drivers of demographic disparities.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outcomes of spontaneous pneumothorax in neonates: treatments vs. expectant management. 新生儿自发性气胸的结局：治疗vs.预期治疗

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-03-15 DOI: 10.1038/s41372-025-02259-4

Anat Margaliot, Laurence Mangel, Yarden Waxman, Moria Be'er, Ronella Marom, Jacky Herzlich

{"title":"Outcomes of spontaneous pneumothorax in neonates: treatments vs. expectant management.","authors":"Anat Margaliot, Laurence Mangel, Yarden Waxman, Moria Be'er, Ronella Marom, Jacky Herzlich","doi":"10.1038/s41372-025-02259-4","DOIUrl":"https://doi.org/10.1038/s41372-025-02259-4","url":null,"abstract":"Background: Neonatal pneumothorax is dependent on severity of symptoms and leak size. Treatment of Pneumothorax with Nitrogen washout is controversial.Objective: To compare outcomes of neonates treated for spontaneous pneumothorax (SP) compared with those managed expectantly.Methods: A retrospective review of medical records of neonates (≥34weeks) diagnosed with SP born between 2011 and 2021. Neonatal characteristics and outcomes were compared between neonates treated for SP with either targeted oxygen therapy (to stabilize saturation ≥93%) or nitrogen washout and those under expectant management.Results: Among neonates with respiratory distress and desaturation (n = 64), nitrogen washout reduced median time to resolution compared to targeted oxygen therapy (31 [12-67] vs 81 [31.8-123.5] hours, p = 0.012). Expectantly managed neonates with distress (n = 87) experienced delayed feeding initiation, while time to resolution and hospital stay were similar.Conclusion: Nitrogen washout is superior to targeted oxygen therapy in time to resolution in infants presenting with respiratory distress and desaturation.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

It's the little things. A framework and guidance for programs to care for infants 22-23 weeks' gestational age. 这是一些小事情。22-23周胎龄婴儿护理方案框架和指南。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-03-10 DOI: 10.1038/s41372-025-02252-x

Laura B Bernardini, Helen Healy, Ashley N Battarbee, Elizabeth Brennick, Paige Church, Leeann R Pavlek, Thea Tagliaferro, Colm Travers, Kourtney Vier, Jennifer Walsh, Matthew A Rysavy

引用次数: 0

Does ventilatory assistance before umbilical cord clamping reduce the risk of early death or intraventricular hemorrhage in extremely preterm infants? 脐带夹紧前的呼吸辅助是否能降低极早产儿早期死亡或脑室内出血的风险？

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-03-08 DOI: 10.1038/s41372-025-02258-5

Kaquanta Barlow, Shoshana Newman-Lindsay, Evan Giusto, Anup Katheria, Satyan Lakshminrusimha

引用次数: 0

Electrical impedance tomography imaging of ventilation and perfusion in bronchopulmonary dysplasia. 支气管肺发育不良患者通气和灌注的电阻抗断层成像。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-03-07 DOI: 10.1038/s41372-025-02236-x

Katelyn G Enzer, Nilton Barbosa da Rosa, Christopher Rocheleau, Gary Saulnier, Jennifer L Mueller, Christopher D Baker

引用次数: 0

Diagnostic evaluation to identify infection-attributable stillbirth. 诊断评估以确定感染导致的死胎。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-03-06 DOI: 10.1038/s41372-025-02253-w

Sarah A Coggins, Jourdan E Triebwasser, Karen M Puopolo

{"title":"Diagnostic evaluation to identify infection-attributable stillbirth.","authors":"Sarah A Coggins, Jourdan E Triebwasser, Karen M Puopolo","doi":"10.1038/s41372-025-02253-w","DOIUrl":"https://doi.org/10.1038/s41372-025-02253-w","url":null,"abstract":"Objective: To characterize stillbirth evaluations, including the frequency and yield of investigations for infections causing stillbirth.Study design: Retrospective cohort of stillbirths at three university-affiliated perinatal centers from 2017 to 2022. The primary outcome was adherence to American College of Obstetrics and Gynecology core stillbirth evaluation recommendations (placental pathology, fetal autopsy, and fetal genetic testing). We further characterized the prevalence and yield of specific testing to evaluate for infection-attributable stillbirth etiologies.Results: The cohort included 399 stillbirths. Placental pathology was performed in 387 cases (97.0%), fetal genetic testing in 163 (40.9%), and fetal autopsy in 126 (31.6%). Fetal bacterial cultures were obtained in 73 (18.2%) cases; potential pathogens were isolated in 21/73 (28.8%). Viral testing was sent infrequently, with variable yield. Six stillbirths had infections identified as probable etiologies.Conclusions: Adherence to core stillbirth evaluation recommendations was poor, and infection testing was infrequent. Infection-attributable stillbirth prevalence may be underestimated.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A prospective randomized pilot trial comparing weekly vs. biweekly Darbepoetin administration to preterm infants. 一项前瞻性随机试验，比较了早产儿每周服用达贝泊汀与每两周服用达贝泊汀的情况。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-03-06 DOI: 10.1038/s41372-025-02247-8

Timothy M Bahr, Robert D Christensen, Kimberlee A Weaver-Lewis, Danielle M Scott, Erick Gerday, Jared J Tuttle, Robin K Ohls

{"title":"A prospective randomized pilot trial comparing weekly vs. biweekly Darbepoetin administration to preterm infants.","authors":"Timothy M Bahr, Robert D Christensen, Kimberlee A Weaver-Lewis, Danielle M Scott, Erick Gerday, Jared J Tuttle, Robin K Ohls","doi":"10.1038/s41372-025-02247-8","DOIUrl":"https://doi.org/10.1038/s41372-025-02247-8","url":null,"abstract":"Background: Administering darbepoetin (Darbe) to preterm infants stimulates erythropoiesis, increases red blood cell (RBC) mass, and reduces RBC transfusions. We typically administer 10 µg/kg weekly until 34 weeks corrected gestation; however, we are uncertain whether this dose could be given every other week (biweekly) with equal efficacy.Methods: Infants ≤32 weeks were randomized to receive Darbe 10 µg/kg/dose weekly or biweekly for six weeks, tracking complete blood counts, absolute reticulocyte counts (ARC), iron status (RET-He), and RBC transfusions.Results: We enrolled 71 infants (1027 ± 369 grams, 27.3 ± 2.8 weeks). During the study period, the weekly-dosed group had a higher adjusted mean ARC (48,000/μL higher, 95% C.I. 9700-87,000/μL; p = 0.019). However, RET-He, Hgb, and transfusion-free survival were not different between groups (p = 0.071, p = 0.244, and p = 0.762).Conclusions: Weekly Darbe results in a higher six-week ARC than biweekly dosing. However, given similar clinical outcomes, perhaps biweekly dosing may be a cost-effective alternative.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interpersonal relationships after prenatal diagnosis of congenital heart disease: Social stressors and supports. 先天性心脏病产前诊断后的人际关系：社会压力源与支持。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-03-06 DOI: 10.1038/s41372-025-02250-z

Emily Marshall, Colette Gramszlo, Alejandra Perez Ramirez, Anne E Kazak, Amanda J Shillingford, Cynthia M Ortinau, Sarah L Kelly, Nadine Kasparian, Lindsay A Edwards, Allison A Divanovic, Jo Ann Davis, Samantha C Butler, Katherine Braley, Erin Riegel, Erica Sood

{"title":"Interpersonal relationships after prenatal diagnosis of congenital heart disease: Social stressors and supports.","authors":"Emily Marshall, Colette Gramszlo, Alejandra Perez Ramirez, Anne E Kazak, Amanda J Shillingford, Cynthia M Ortinau, Sarah L Kelly, Nadine Kasparian, Lindsay A Edwards, Allison A Divanovic, Jo Ann Davis, Samantha C Butler, Katherine Braley, Erin Riegel, Erica Sood","doi":"10.1038/s41372-025-02250-z","DOIUrl":"https://doi.org/10.1038/s41372-025-02250-z","url":null,"abstract":"Objective: To identify social stressors and supports for expectant parents after prenatal diagnosis of congenital heart disease (CHD) and inform interventions to reduce distress.Method: Parents of children diagnosed prenatally with CHD (N = 37) were purposively sampled across eight health systems. Qualitative data were collected using crowdsourcing methods and coded/analyzed using thematic analysis.Results: Social stressors increasing distress after prenatal diagnosis were widely endorsed: (1) feelings of loneliness (most common: 68%), (2) well-meaning yet unhelpful comments, (3) loss of celebration of pregnancy, (4) information overload, and (5) untimely/insensitive discussions surrounding pregnancy termination. Social supports included: (1) emotional support and small acts of kindness, (2) hope/connection through the experiences of others, (3) informational support, (4) nurturing normalcy and the joy of pregnancy, and (5) connection through religion/spirituality.Conclusion: Interpersonal relationships are vital for coping with prenatal diagnosis. Interventions to reduce distress after prenatal diagnosis should attend to common social stressors.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Voices of parents of children with major congenital anomalies admitted to the NICU: initial diagnosis, hospitalization, and discharge home. 新生儿重症监护室收治的重大先天性畸形患儿父母的声音：初步诊断、住院和出院。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-03-05 DOI: 10.1038/s41372-025-02255-8

Jessica Lyon, Natalie McAndrew, Alexis Geich, Tala AbuZahra, Steven R Leuthner, Joanne Lagatta, Krishna Acharya

{"title":"Voices of parents of children with major congenital anomalies admitted to the NICU: initial diagnosis, hospitalization, and discharge home.","authors":"Jessica Lyon, Natalie McAndrew, Alexis Geich, Tala AbuZahra, Steven R Leuthner, Joanne Lagatta, Krishna Acharya","doi":"10.1038/s41372-025-02255-8","DOIUrl":"10.1038/s41372-025-02255-8","url":null,"abstract":"Objective: To identify challenges vs. supports in the NICU and after NICU discharge for parents of an infant with a major congenital anomaly.Study design: Qualitative study.Results: We interviewed 18 parents (13 mothers, 5 fathers) whose children were admitted to our our NICU with a major congenital anomaly. In the NICU, challenges were navigating parenthood with significant impact on parent mental health, adjusting to changing healthcare providers, and need for better interdisciplinary communication. After discharge home, challenges were an initial adjustment to life without NICU monitoring, loss of NICU medical resources, burden of caregiving, continued healthcare utilization, and financial impact.Conclusion: Key supports that were helpful to families were empathetic and consistent healthcare teams throughout their care journey, especially nurses; healthcare team members who went beyond medical care, consistent communication, parent engagement in NICU care, ongoing parent mental health support, and peer resources after discharge home.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extended-spectrum β-lactamase-producing Enterobacterales infections among infants following vertical colonization in a neonatal intensive care unit. 新生儿重症监护病房垂直定植后婴儿中产β-内酰胺酶肠杆菌的广谱感染

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-03-05 DOI: 10.1038/s41372-025-02256-7

Mimori Abe, Yuto Otsubo, Tomoyuki Tame, Kaoru Okazaki, Yuho Horikoshi

{"title":"Extended-spectrum β-lactamase-producing Enterobacterales infections among infants following vertical colonization in a neonatal intensive care unit.","authors":"Mimori Abe, Yuto Otsubo, Tomoyuki Tame, Kaoru Okazaki, Yuho Horikoshi","doi":"10.1038/s41372-025-02256-7","DOIUrl":"10.1038/s41372-025-02256-7","url":null,"abstract":"Objective: Extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) has become prevalent among neonates. The present study aimed to describe the incidence of ESBL-E colonization among neonates admitted to a NICU and the incidence of subsequent ESBL-E infection among those with ESBL-E colonization.Study design: Patients admitted to the NICU at Tokyo Metropolitan Children's Medical Center between April 2011 and March 2023 were enrolled. On admission, the subjects were routinely screened for ESBL-E using pharyngeal and rectal swabs, and those colonized with ESBL-E were assessed for the development of an invasive ESBL-E infection during their NICU stay.Results: ESBL-E was isolated in 105 of the 8247 neonates (1.3%) admitted to the NICU. Among these patients, 12 (11.4%) experienced the development of an invasive ESBL-E infection.Conclusion: Although ESBL-E colonization occurred in only 1.3% of the neonates admitted to the NICU, 11.4% of them experienced the development of an ESBL-E infection.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0