Journal of Perinatology最新文献_第10页

Bifidobacterium longum subsp infantis (EVC001) is associated with reduced incidence of necrotizing enterocolitis stage ≥2 and bloody stools in premature babies. 婴儿长双歧杆菌亚种（EVC001）与早产儿坏死性小肠结肠炎≥2期和血便发生率降低相关。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-05-01 Epub Date: 2024-12-06 DOI: 10.1038/s41372-024-02188-8

Kristin Sohn, Victoria Palacios, Reese Clark

{"title":"Bifidobacterium longum subsp infantis (EVC001) is associated with reduced incidence of necrotizing enterocolitis stage ≥2 and bloody stools in premature babies.","authors":"Kristin Sohn, Victoria Palacios, Reese Clark","doi":"10.1038/s41372-024-02188-8","DOIUrl":"10.1038/s41372-024-02188-8","url":null,"abstract":"Objective: To utilize an evidence-based probiotic protocol to achieve a 50% reduction in necrotizing enterocolitis (NEC) ≥ stage 2 and bloody stools.Study design: From January 2022 through September 2023, daily enteral Bifidobacterium longum ssp. infantis EVC001 (B. infantis EVC001) was administered to babies ≤ 33 6/7 weeks gestation until 36 weeks post menstrual age. Feeding tolerance and complications were compared to babies admitted during the prior two-year period. Fisher's Exact test was used to analyze proportional data and t test was used for continuous variables.Results: A total of 265 babies received EVC001, and a total of 277 babies formed the pre-probiotic cohort. Probiotic use was associated with decreased NEC ≥ stage 2 (p = 0.0058), reduced bloody stools (p < 0.0001), decreased time to full enteral feeds (p < 0.0001), and decreased total parenteral nutrition (TPN) days (p < 0.0001).Conclusion: Administration of B. infantis EVC001 was associated with a decrease in NEC, a decrease in bloody stools, and improvement in feeding tolerance in premature babies.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":"635-641"},"PeriodicalIF":2.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12222014/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Birth outcomes of individuals who have experienced incarceration during pregnancy. 在怀孕期间经历过监禁的人的分娩结果。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-05-01 Epub Date: 2024-11-13 DOI: 10.1038/s41372-024-02170-4

Emma Rose Miller-Bedell, Lillian Sie, Suzan L Carmichael, Nana Matoba, Ya'el Weiner, Joseph J Kim, Arash Anoshiravani, Dominika Seidman, Deirdre J Lyell, Henry C Lee

{"title":"Birth outcomes of individuals who have experienced incarceration during pregnancy.","authors":"Emma Rose Miller-Bedell, Lillian Sie, Suzan L Carmichael, Nana Matoba, Ya'el Weiner, Joseph J Kim, Arash Anoshiravani, Dominika Seidman, Deirdre J Lyell, Henry C Lee","doi":"10.1038/s41372-024-02170-4","DOIUrl":"10.1038/s41372-024-02170-4","url":null,"abstract":"Objectives: Describe the prevalence, health, and birth outcomes of incarcerated pregnant individuals in California between 2011 and 2015.Study design: A population-based cohort study was performed using linked birth certificate and hospital discharge data. Associations between incarceration and birth outcomes were examined, including multivariable logistic regression to estimate odds ratios and 95% confidence intervals.Results: Amongst 1401 incarcerated and 551,029 nonincarcerated pregnant people across 112 delivery hospitals, 33% of incarcerated individuals had late initiation of prenatal care; 2.4% experienced severe maternal morbidity, compared to 18.9% and 1.6% of controls, respectively (p < 0.05). Births to incarcerated individuals had higher adjusted likelihoods of prematurity (OR 1.42, 95% CI 1.21, 1.67), small for gestational age (OR 1.31, 95% CI 1.11, 1.56), and NICU admission (OR 1.64, 95% CI, 1.40, 1.93) relative to controls.Conclusion: Incarcerated individuals have greater likelihood of negative birth outcomes. Identification of approaches to reduce these harms is warranted.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":"600-606"},"PeriodicalIF":2.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12222011/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Demographic and clinical predictors and inter-center variability of tube feeding in preterm NICU patients. 新生儿重症监护病房早产儿管饲的人口学和临床预测因素及中心间变异性。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-04-24 DOI: 10.1038/s41372-025-02314-0

Pavika Varma, Isabella Zaniletti, Karna Murthy, Theresa R Grover, Sunah S Hwang, Stephanie L Bourque

{"title":"Demographic and clinical predictors and inter-center variability of tube feeding in preterm NICU patients.","authors":"Pavika Varma, Isabella Zaniletti, Karna Murthy, Theresa R Grover, Sunah S Hwang, Stephanie L Bourque","doi":"10.1038/s41372-025-02314-0","DOIUrl":"https://doi.org/10.1038/s41372-025-02314-0","url":null,"abstract":"Objectives: Investigate demographic and clinical factors and inter-center variability associated with home NGT versus GT in preterm infants.Study design: Retrospective cohort study of preterm infants in the Children's Hospitals Neonatal Database discharged home with a NGT or GT between 2015-2020. Multivariable logistic regression assessed the independent relationship between infant characteristics and feeding modality. Bivariate analysis evaluated inter-center variability.Results: 3521 preterm infants discharged with tube feedings (NGT 39%; GT 61%). Hispanic infants (AOR 1.57, 95% CI 1.15, 2.14) and SGA infants (AOR 1.27, 95% CI 1.02, 1.6) were more likely to receive GT feedings. Privately insured infants had decreased likelihood of receiving GT (AOR 0.57, 95% CI 0.45, 0.72). Infants discharged with NGT had shorter hospital stays (70[34,111] vs. 86 [39,138] days, p < 0.01). Significant inter-center variability among sites exists.Conclusions: Differences in tube feeding at discharge were noted by infant race and ethnicity, SGA status, and insurance type.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

National survey of diagnostic point of care ultrasound practices and program development in academic neonatal-perinatal medicine centers. 全国调查诊断点护理超声实践和程序发展的学术新生儿-围产期医学中心。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-04-22 DOI: 10.1038/s41372-025-02307-z

Kathleen Miller, J Lauren Ruoss, Diana Vargas Chaves, Belinda Chan, Matthew Huber, Jason Z Stoller, María V Fraga, Heather French, Thomas Conlon, William Corder

{"title":"National survey of diagnostic point of care ultrasound practices and program development in academic neonatal-perinatal medicine centers.","authors":"Kathleen Miller, J Lauren Ruoss, Diana Vargas Chaves, Belinda Chan, Matthew Huber, Jason Z Stoller, María V Fraga, Heather French, Thomas Conlon, William Corder","doi":"10.1038/s41372-025-02307-z","DOIUrl":"https://doi.org/10.1038/s41372-025-02307-z","url":null,"abstract":"Objective: To assess diagnostic point of care ultrasound (POCUS) use, presence of programmatic infrastructural elements, and barriers to implementation across neonatal perinatal medicine (NPM) programs in the United States.Study design: Cross-sectional study. An online survey was distributed to leaders in education or POCUS at ACGME-accredited NPM fellowship programs. National trends were outlined using descriptive statistics and compared by program size.Result: 79 of 99 (80%) NPM programs responded. Diagnostic POCUS was available at 71% (n = 56) of sites that responded. Key infrastructural elements were present at <45% of sites, with fellow training being the exception (71%). Many barriers to diagnostic POCUS program implementation were identified and they differed by program size.Conclusion: Diagnostic POCUS is being increasingly adopted despite underdeveloped programmatic infrastructure. Identified barriers suggest a need for collaborative efforts to support the necessary infrastructural elements, and differences by program size suggest a need for tailored approaches for successful integration.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and implementation of restrictive platelet transfusion thresholds in a neonatal intensive care unit. 限制性血小板输血阈值在新生儿重症监护病房的发展和实施。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-04-21 DOI: 10.1038/s41372-025-02302-4

Natasha Lalos, Alexa Brumfiel, Luke T Viehl, Gillian C Pet, Alexandra Lahart

{"title":"Development and implementation of restrictive platelet transfusion thresholds in a neonatal intensive care unit.","authors":"Natasha Lalos, Alexa Brumfiel, Luke T Viehl, Gillian C Pet, Alexandra Lahart","doi":"10.1038/s41372-025-02302-4","DOIUrl":"https://doi.org/10.1038/s41372-025-02302-4","url":null,"abstract":"Objective: Thrombocytopenia is a common problem affecting preterm neonates. Recent studies show increased morbidity and mortality with liberal platelet transfusion thresholds. We sought to standardize thrombocytopenia management through a transfusion guideline to reduce excessive transfusions.Study design: We developed and implemented a guideline using PDSA cycles for infants with birth weights <1000 grams. Platelet transfusions were classified as indicated or non-indicated per the guideline. Severe (grade 3 or 4) intraventricular hemorrhage and pulmonary hemorrhage rates were balancing measures.Results: We analyzed 101 infants pre-guideline and 96 infants post-guideline. The mean monthly non-indicated transfusions significantly decreased from 13.0 to 2.0, respectively (p-value < 0.01). Incidence of severe grade IVH and pulmonary hemorrhage remained stable.Conclusion: Rapid implementation of an evidence-based, restrictive platelet transfusion guideline significantly reduced non-indicated platelet transfusions without a concomitant increase in major bleeding events.","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143998361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exclusive human milk diet is associated with lower risk of motor function impairment at three years of corrected age. 纯母乳饮食与三岁矫正年龄运动功能障碍的风险较低有关。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-04-21 DOI: 10.1038/s41372-025-02296-z

Fu-Sheng Chou, Jing Zhang, Maria Fe B Villosis, Ashwini Lakshmanan

引用次数: 0

Proteinuria in preterm neonates: influence of fetal growth restriction. 早产儿蛋白尿：胎儿生长受限的影响。

IF 2.4 3区医学

Journal of Perinatology Pub Date : 2025-04-19 DOI: 10.1038/s41372-025-02306-0

Arvind Sehgal, Criona Levins, Emma Yeomans, Zhong Lu, David Metz

引用次数: 0

Neonatologists' perceptions of uncertainty: a national survey. 新生儿学家对不确定性的看法：一项全国性调查。