纯母乳饮食与三岁矫正年龄运动功能障碍的风险较低有关。

IF 2.4 3区医学 Q2 OBSTETRICS & GYNECOLOGY

Journal of Perinatology Pub Date : 2025-04-21 DOI:10.1038/s41372-025-02296-z

Fu-Sheng Chou, Jing Zhang, Maria Fe B Villosis, Ashwini Lakshmanan

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引用次数: 0

摘要

目的：评估纯母乳饮食（EHMD）与孕32周前出生的3岁矫正年龄婴儿运动功能障碍之间的关系。方法：我们在2018 - 2021年间进行了回顾性研究。我们将在饮食强化第一天至经后33 6/7周之间接受EHMD≥75%天数的婴儿分配到EHMD组。我们使用逆倾向得分来平衡潜在的混杂因素，并开发了一个混合效应逻辑回归模型来评估相关性。结果：在调整人口统计学和发病率后，EHMD与运动功能障碍风险降低相关，优势比为0.74 （95% CI: 0.56-0.98, p = 0.036）。结论：在妊娠32周前出生的婴儿中，EHMD与早期儿童运动功能障碍的几率降低有关。

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Exclusive human milk diet is associated with lower risk of motor function impairment at three years of corrected age.

Objectives: To evaluate the association between an exclusive human milk diet (EHMD) and motor function impairment at three years of corrected age among infants born before 32 weeks of gestation.

Methods: We conducted a retrospective study between 2018 and 2021. We assigned to the EHMD group infants who received an EHMD for ≥75% of the days between the first day of diet fortification and 33 6/7 weeks postmenstrual age. We used inverse propensity scores to balance potential confounders and developed a mixed-effects logistic regression model to assess the association.

Results: After adjusting for demographics and morbidities, an EHMD was associated with a reduced risk of motor function impairment, with an odds ratio of 0.74 (95% CI: 0.56-0.98, p = 0.036).

Conclusions: An EHMD is associated with a decrease in the odds of early childhood motor function impairment among infants born before 32 weeks of gestation.

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来源期刊

Journal of Perinatology 医学-妇产科学

CiteScore

5.40

自引率

6.90%

发文量

284

审稿时长

3-8 weeks

期刊介绍： The Journal of Perinatology provides members of the perinatal/neonatal healthcare team with original information pertinent to improving maternal/fetal and neonatal care. We publish peer-reviewed clinical research articles, state-of-the art reviews, comments, quality improvement reports, and letters to the editor. Articles published in the Journal of Perinatology embrace the full scope of the specialty, including clinical, professional, political, administrative and educational aspects. The Journal also explores legal and ethical issues, neonatal technology and product development. The Journal’s audience includes all those that participate in perinatal/neonatal care, including, but not limited to neonatologists, perinatologists, perinatal epidemiologists, pediatricians and pediatric subspecialists, surgeons, neonatal and perinatal nurses, respiratory therapists, pharmacists, social workers, dieticians, speech and hearing experts, other allied health professionals, as well as subspecialists who participate in patient care including radiologists, laboratory medicine and pathologists.