Journal of Pain Research最新文献

{"title":"Editorial: Pain Medicine Training in Latin America.","authors":"Rodrigo Díez-Tafur, Matthew Slitzky, Carlos Guerrero-Nope, Ricardo Plancarte-Sanchez, Jesús Medina-Rascon, Carlos Eduardo Restrepo-Garces, Juan Felipe Vargas-Silva, Carlos Marcelo de Barros, Fabricio Dias Assis, Camila Lobo, Andrés Rocha-Romero, Juan Pablo Paladino, Wendy Rojas-Gareca, César R Carcamo-Quezada, Juan Carlos Sosa Nicora, Angie Navarrete, Soraya Mariuxi Cruz Loor, Claudia B Cruz-Ayala, Lisbeth Godinez Ortiz, Sudhir Diwan, Michael E Schatman, Christopher L Robinson, Victor M Silva-Ortiz","doi":"10.2147/JPR.S504547","DOIUrl":"https://doi.org/10.2147/JPR.S504547","url":null,"abstract":"","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4033-4038"},"PeriodicalIF":2.5,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Erector Spinae Plane Blocks on Pain Management and Postoperative Outcomes in Patients with Chronic Pain Undergoing Spine Fusion Surgery: A Retrospective Cohort Study.","authors":"Krizia Amoroso, James A Beckman, Jiaqi Zhu, Erika Chiapparelli, Ali E Guven, Jennifer Shue, Andrew A Sama, Federico P Girardi, Frank P Cammisa, Alexander P Hughes, Ellen M Soffin","doi":"10.2147/JPR.S483144","DOIUrl":"https://doi.org/10.2147/JPR.S483144","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the impact of bilateral ultrasound-guided erector spinae plane blocks (ESPBs) on pain and opioid-related outcomes in a surgical population with chronic pain.</p><p><strong>Methods: </strong>A retrospective, observational cohort study. Clinical data were extracted from the electronic medical records of patients who underwent lumbar fusion (February 2018 - July 2020). Eligible patients had a confirmed history/diagnosis of chronic pain starting >3 months before surgery and received either bilateral ESPBs or no ESPBs. Patients were matched on demographic variables (sex, age, race, BMI, ASA Classification, and preoperative opioid use) in a 1:1 ratio. The primary outcome was median opioid consumption (morphine equivalent dose, MED) 24 hours post-surgery (hydromorphone iv-PCA and oral). Secondary outcomes included Numeric Rating Scale (NRS) pain scores, opioid consumption up to 48 hours post-surgery, and hospital length of stay (LOS). Group differences were analyzed using bivariable and multivariable regression.</p><p><strong>Results: </strong>Of 72 patients, 36 received ultrasound-guided ESPBs and 36 did not. Baseline demographics showed no significant differences. On bivariable analysis, ESPBs were associated with significantly lower 24-hour opioid consumption (79 mg MED vs 116 mg MED, p=0.024) and shorter LOS (82 hours, 95% CI 51-106 vs 126 hours, 95% CI 101-167, p<0.001). No significant differences in NRS pain scores were found up to 48 hours post-surgery. Multivariable analysis confirmed significant reductions in 24-hour opioid consumption (-44, 95% CI -1.06 - -87.55, p=0.044), IV-PCA use (-22, 95% CI -1.59 - -56.77, p=0.038), and LOS (-38, 95% CI -10.074 - -66.22, p=0.008) in the ESPB group without differences in NRS pain scores.</p><p><strong>Conclusion: </strong>ESPBs were associated with statistically and clinically significant reductions in 24-hour opioid consumption and LOS, without differences in NRS pain scores after spinal fusion in a chronic pain surgical cohort. Given these effects, patients with chronic pain may disproportionately benefit from ESPBs for spine surgery.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4023-4031"},"PeriodicalIF":2.5,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The CT-Imaging Location of Lumbar 3 Sympathetic Radiofrequency Thermocoagulation for Sympathetic-Related Diseases Therapy.","authors":"Ruxiang Wang, Zhuoyue Gao, Ling Ma","doi":"10.2147/JPR.S473078","DOIUrl":"https://doi.org/10.2147/JPR.S473078","url":null,"abstract":"<p><strong>Purpose: </strong>The location characteristic of the lumbar 3 sympathetic trunk under Computed Tomography (CT) was discovered through 106 cases, imaging analysis after successful lumbar 3 sympathetic radiofrequency thermocoagulation operations serving the clinic and reducing the operation time.</p><p><strong>Methods: </strong>There are 113 patients underwent bilateral L3 lumbar sympathetic thermal radiofrequency procedures in our hospital from January 2017 to January 2021, with 106 cases of successful procedure. Four operation image distances were measured: 1. The left/right distances between the needle tip (the location of needle tip was the sympathetic trunk at the same CT scan level) and the transverse process of the lumbar spine (D1l/D1r); 2. The left/right distances between the needle tip and the medial margin of the psoas major (D2l/D2r); 3. The left/right vertical distances between the needle tip and vertebral body (D3l/D3r); 4. The left/right vertical distances between ureter and vertebral body (D4l/D4r). The Perfusion Index (PI) and the plantar temperature were monitored and recorded before and after the treatment (the higher PI value and the plantar temperature indicated successful procedure). After the procedure, the patients were followed up one day, one week, two months and six months for satisfaction, complications and recurrences.</p><p><strong>Results: </strong>The left distance (D1l) from the needle tip to the transverse costal process being 4.444±0.7668mm, longer than the right side (D1r, P<0.001). The left distance (D2l) being 1.260±0.4261mm longer than the right side (D2r, P=0.0039). The left distance (D3l) was 1.634±0.2597mm longer than the right side (D3r, P<0.0001). The D4l and D4r both having a long distance far from needle tips (P=0.665). Both the left and right temperature and PI increased have statistical significances after treatment (P<0.0001). There were 2(1.77%) cases experiencing numbness of big thighs, and 9(7.96%) cases of compensatory hyperhidrosis, with only 3 (2.65%) cases reverting to the original state six months later.</p><p><strong>Conclusion: </strong>Lumbar sympathetic radiofrequency thermocoagulation is a valid treatment option for sympathetic-related disease in lower limbs, and based on our study data CT-guided percutaneous puncture lumbar sympathectomy can easy be proceed and gained more persistent effection, the left needle distance more deeper than the right side, the distance from the left side should be far from vertebral body than the right side. The distance between the needle body and the vertebral body on the left side is far away from the right side.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4011-4022"},"PeriodicalIF":2.5,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Risk Factors Causing Adjacent Disc Degeneration After Percutaneous Kyphoplasty for Osteoporotic Vertebral Compression Fractures.","authors":"He Song, Aobo Wang, Lei Zang, Tianyi Wang, Shuo Yuan, Ning Fan, Peng Du","doi":"10.2147/JPR.S486668","DOIUrl":"https://doi.org/10.2147/JPR.S486668","url":null,"abstract":"<p><strong>Purpose: </strong>Adjacent disc degeneration (ADD) is a common postoperative complication after percutaneous kyphoplasty (PKP). However, risk factors for ADD after PKP have not been reported. This study aimed to determine whether osteoporotic vertebral compression fracture (OVCF) following PKP is associated with a high risk for ADD and to identify the risk factors for ADD.</p><p><strong>Patients and methods: </strong>Consecutive patients who underwent PKP at our center between January 2015 and January 2021 were retrospectively reviewed. The incidence of ADD was calculated and specific subgroups of ADD were identified. Demographic, clinical baseline, and radiologic data were analyzed using univariate and multivariate analyses to identify the risk factors associated with ADD.</p><p><strong>Results: </strong>130 eligible patients were included, and the incidence rate of ADD distinct from primary degeneration was 42.3%. Patients with OVCFs who underwent PKP had a high risk of developing ADD. The independent risk factors included the presence of intradiscal cement leakage (ICL; odds ratio [OR] 6.292; 95% confidence interval [CI] 2.588-15.299; <i>P</i> < 0.001) and pre-operative cranial disc of the injured vertebrae degeneration (Pfirrmann grade ≥IV; OR 3.575; 95% CI 1.515-8.438; <i>P</i> = 0.004).</p><p><strong>Conclusion: </strong>Patients with OVCFs who underwent PKP were more likely to develop ADD, and most of the degenerated discs occurred in the vertebrae above the level of injury. ICL and pre-operative cranial disc of the injured vertebrae degeneration (Pfirrmann grade ≥IV) were independent risk factors for developing ADD in these patients.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"3985-3995"},"PeriodicalIF":2.5,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11606712/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Experience Sampling Method in Small Fiber Neuropathy: The Influence of Psychosocial Factors on Pain Intensity and Physical Activity.","authors":"Aysun Damci, Janneke G J Hoeijmakers, Marlies den Hollander, Catharina G Faber, Sophie Waardenburg, Charlotte C M van Laake-Geelen, Albère J A Köke, Jeanine A M C F Verbunt","doi":"10.2147/JPR.S481274","DOIUrl":"https://doi.org/10.2147/JPR.S481274","url":null,"abstract":"<p><strong>Purpose: </strong>Small fiber neuropathy (SFN) is characterized by neuropathic pain, associated with decreased quality of life (QOL). It remains unclear which psychosocial factors play a role in SFN. The experience sampling method (ESM) allows a profound understanding of the real-time fluctuations in reaction to events. The main goal of this study was to increase knowledge of the interrelationships between pain intensity, physical activity, and psychosocial factors in patients with SFN in daily practice over time.</p><p><strong>Patients and methods: </strong>A prospective observational ESM study with the PsyMate© application (smart-eHealth GmbH, Luxembourg) was conducted at the Adelante location of Maastricht University Medical Center+ in the Netherlands. Participants with idiopathic SFN, older than 18 years, with an indication for rehabilitation, were included. Pain intensity, fatigue, positive and negative affect, physical activity, avoidance behavior, and pain catastrophic thoughts were incorporated into the ESM questions. Participants received 10 beep signals per day followed by the above-mentioned questions, for consecutive 7 days. The results were analyzed with linear mixed-effect models.</p><p><strong>Results: </strong>Twenty-one participants were included with a mean age of 48.24 (SD ± 13.89) years, of whom 76.2% were female. More pain (now) resulted in more physical activity (later) (a) and more physical activity (now) resulted in more pain (later) (b). The first association (a) is influenced by pain catastrophic thoughts and fatigue, and the second (b) by an increase in affective states and a lower level of avoidance behavior.</p><p><strong>Conclusion: </strong>In idiopathic SFN, pain intensity, and physical activity showed a 2-sided association, influenced by catastrophic thoughts, fatigue, affective states, and avoidance behavior.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"3997-4010"},"PeriodicalIF":2.5,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11606713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-Time Ultrasound-Guided CT-Monitored Percutaneous Cervical Disc Injection: An Emerging Approach for Accurate Diagnosis of Cervical Discogenic Diseases.","authors":"Haimiti Abudouaini, Junsong Yang, Meng Li, Pingzheng Zhang, Kaiyuan Lin, Yonghong Jiang, Kongjiang Tao, Hong Zhang","doi":"10.2147/JPR.S480008","DOIUrl":"10.2147/JPR.S480008","url":null,"abstract":"<p><strong>Objective: </strong>To explore the preliminary application value of real-time ultrasound-guided combined with CT monitoring in percutaneous cervical disc puncture injection for diagnostic trials.</p><p><strong>Methods: </strong>Sixty patients with suspected cervical discogenic dizziness undergoing percutaneous cervical disc puncture between January 2023 and February 2024 were randomly divided into two groups: real-time ultrasound-guided combined with CT monitoring and CT-guided alone. The groups were compared for pre-puncture positioning time, total puncture process time, number of CT exposures, and complications. Subsequent treatment and medications were consistent between the two groups.</p><p><strong>Results: </strong>Sixty patients were divided into the the real-time US-guided combined with CT monitoring group (n=30) and the CT-guided group (n=30). Pre-puncture positioning time in the real-time US-guided combined with CT monitoring group was shorter than that in the CT-guided group, but there was no statistical difference between the two groups (P>0.05). The total puncture process time and the number of CT exposures in the real-time US-guided combined with CT monitoring group were smaller than those in the CT-guided group, and there was a statistical difference between the two groups (P<0.05). Two cases of hematoma appeared in CT guidance alone, and no hematoma appeared in the real-time US-guided combined with CT monitoring group.</p><p><strong>Conclusion: </strong>Real-time ultrasound-guided combined with computed tomography monitoring in percutaneous cervical disc puncture is a rapid, visible, safe, and effective method.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"3975-3983"},"PeriodicalIF":2.5,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11600919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regarding \"Musculoskeletal Ultrasound Assessment of the Clinical Efficacy of the Combination of Acupressure and 'Three Methods of Neck Movement (TCM)' Therapy in the Treatment of Cervical Spondylosis\" [Response to Letter].","authors":"Jinhong Zuo, Xiayang Zeng, Hongyi Ma, Peng Chen, Xinlei Cai, Zhenyu Fan, Jianpeng Qu","doi":"10.2147/JPR.S506885","DOIUrl":"https://doi.org/10.2147/JPR.S506885","url":null,"abstract":"","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"3973-3974"},"PeriodicalIF":2.5,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11600931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of Specific Abnormal Brain Functional Activity and Connectivity in Cancer Pain Patients: A Preliminary Resting-State fMRI Study.","authors":"Yingjie Hua, Yongkang Geng, Surui Liu, Shuiwei Xia, Yan Liu, Sufang Cheng, Chunmiao Chen, Chunying Pang, Zhongwei Zhao, Bo Peng, Yakang Dai, Jiansong Ji, Dan Wu","doi":"10.2147/JPR.S470750","DOIUrl":"10.2147/JPR.S470750","url":null,"abstract":"<p><strong>Objective: </strong>This study investigates the differences in brain functional activity and connectivity patterns between Cancer Pain (CP) patients and Healthy Controls (HCs) using resting-state functional magnetic resonance imaging (rs-fMRI) to identify potential neuroimaging biomarkers.</p><p><strong>Methods: </strong>This study collected rs-fMRI data from 25 CP patients and 25 hCs, processed the functional MRI images, and calculated metrics such as amplitude of low-frequency fluctuation (ALFF), Regional Homogeneity (ReHo), and FC. Through statistical analysis, differences in brain functional activity and connectivity between the cancer pain group and the healthy control group were investigated, followed by machine learning classification.</p><p><strong>Results: </strong>The results showed that compared to the normal group, reductions in the ALFF were primarily observed in the bilateral inferior temporal gyrus; ReHo increased in the right middle temporal gyrus and decreased in the left cerebellum Crus2. Using the statistically different brain areas as seed points to construct FC networks and performing statistical analysis, it was found that the regions with decreased FC connection strength between the cancer pain group and the normal group were mainly in the prefrontal cortex (PFC), the postcentral gyrus of the parietal lobe, and the cerebellum. Statistical results indicated that there was no significant correlation between pain scores (Numeric Rating Scale, NRS) and neuroimaging metrics. According to the machine learning classification, the FC features of the right precentral gyrus achieved higher diagnostic efficacy (AUC = 0.804) compared to ALFF and ReHo in distinguishing between CP patients and HCs.</p><p><strong>Conclusion: </strong>Brain activity and FC in CP patients show abnormalities in regions such as the inferior temporal gyrus, middle temporal gyrus, prefrontal cortex, parietal lobe, and cerebellum. These areas may be interconnected through neural networks and jointly participate in functions related to pain perception, emotion regulation, cognitive processing, and motor control. However, the precise connections and mechanisms of action require further research.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"3959-3971"},"PeriodicalIF":2.5,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11590652/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142729782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nerve Block Extends Nerve Function Recovery in Patients with Diabetic Foot Ulcers.","authors":"Qiufeng Wei, Heng Rong, Guangying Zhang, Yubo Xie, Weixin Dai","doi":"10.2147/JPR.S491539","DOIUrl":"10.2147/JPR.S491539","url":null,"abstract":"<p><strong>Objective: </strong>Research has revealed that patients with diabetes and peripheral neuropathy exhibit significantly elevated nerve stimulation thresholds. However, the minimum stimulation thresholds of peripheral nerves in patients with diabetic foot, along with the recovery of nerve function, remain undetermined. The aim of this study is to investigate the minimum stimulation thresholds of the femoral and sciatic nerves, as well as the duration of nerve block, in patients diagnosed with diabetic foot.</p><p><strong>Methods: </strong>From July 2020 to March 2022, a prospective study was conducted involving patients aged 50-80 scheduled for distal lower limb surgery. The study included 83 patients with diabetic foot and 48 individuals without diabetes. Prior to surgery, an ultrasound-guided approach combined with nerve stimulation was employed to administer a popliteal sciatic nerve block (20 mL of ropivacaine 5 mg/mL) and a femoral nerve block (20 mL of ropivacaine 5 mg/mL). During the ultrasound-guided femoral and popliteal sciatic nerve blocks, the electric current required to elicit motor activity in both the femoral and popliteal sciatic nerves was assessed.</p><p><strong>Results: </strong>The study revealed that patients with diabetic foot exhibited significantly higher stimulation thresholds for femoral and sciatic nerve blocks, as well as a substantially longer duration of femoral and sciatic sensory and motor blocks (<i>P</i> < 0.01). Additionally, nerve injury was observed in 4 patients (4.8%) within the diabetes mellitus (DM) group.</p><p><strong>Conclusion: </strong>Patients with diabetic foot exhibit higher minimum stimulus thresholds for the femoral and sciatic nerves and experience delayed recovery from ropivacaine block.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"3949-3957"},"PeriodicalIF":2.5,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11590638/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142729784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Mental Health Toll of the COVID-19 Pandemic on Older Adults with Migraine: A Prospective Analysis of Depression Using the Canadian Longitudinal Study on Aging.","authors":"Andie MacNeil, Aneisha Taunque, Sarah N Leo, Grace Li, Margaret de Groh, Ying Jiang, Esme Fuller-Thomson","doi":"10.2147/JPR.S469798","DOIUrl":"10.2147/JPR.S469798","url":null,"abstract":"<p><strong>Background: </strong>Individuals with migraine are recognized to have a heightened risk of depression compared to the general population. The COVID-19 pandemic and associated public health restrictions exacerbated several known risk factors for depression, but limited longitudinal research has examined the impact of the pandemic on the mental health of people with migraine.</p><p><strong>Aim: </strong>To examine the cumulative incidence of depression and recurrent depression among older adults with migraine, and to identify factors associated with depression among older adults with migraine during the pandemic.</p><p><strong>Methods: </strong>Data came from four waves of the Canadian Longitudinal Study on Aging's comprehensive cohort (n=2181 with migraine). The outcome of interest was a positive screen for depression based on the CES-D-10 during the autumn of 2020. Bivariate and multivariate logistic regression analyses were conducted.</p><p><strong>Results: </strong>Older adults with migraine, both with and without a history of depression, experienced increases in depression when compared to pre-pandemic levels, and when compared to older adults without migraine. The risk of incident and recurrent depression was higher among those who felt lonely and those who experienced an increase in family conflict during the pandemic. The risk of incident depression only was higher among those who experienced difficulty accessing healthcare and those who experienced other family challenges, such as increased caregiving responsibilities. The risk of recurrent depression only was higher among those who felt left out socially, those with functional limitations, and those whose income did not satisfy their basic needs.</p><p><strong>Conclusion: </strong>Targeted interventions are needed to support the mental health of older adults with migraine.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"3845-3866"},"PeriodicalIF":2.5,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586004/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}