Journal of Pain Research最新文献

{"title":"Association Between Poor Pain Control and Sensory Impairment: A Cross-Sectional Study.","authors":"Junjian Zeng, Zhiqiang Liao, Aiqing Lin, Yu Zou, Yixun Chen, Zhonghua Liu, Hongqing Luo, Zhidong Zhou","doi":"10.2147/JPR.S504303","DOIUrl":"10.2147/JPR.S504303","url":null,"abstract":"<p><strong>Purpose: </strong>Poor pain control may lead to persistent physical discomfort and even reduced perceptual abilities. This research seeks to investigate the relationship between pain status and duration and sensory impairments.</p><p><strong>Patients and methods: </strong>This study used data on pain and sensory impairments from the National Health and Nutrition Examination Survey (NHANES) conducted from 2011 to 2014, including 8043 participants. Functional status of vision, hearing, smell, and taste was gathered using structured questionnaires. Logistic regression models were used to evaluate the association between pain status, duration, and the total number of sensory impairments and specific sensory deficits, while adjusting for key covariates such as age, gender, BMI, and socioeconomic status. Stratified analysis was performed to determine factors that might confound this relationship.</p><p><strong>Results: </strong>The multivariable-adjusted regression model showed that individuals with pain for 1 to 3 years had a 64% increased risk of sensory impairment compared to those without pain (OR 1.640, 95% CI 1.132-2.376, <i>P</i> = 0.016), while those with pain for over 3 years had a 90.9% increased risk (OR 1.909, 95% CI 1.472-2.475, <i>P</i> = 0.001). We also found a statistically significant association between pain duration of ≥ 1 year and visual impairment (OR 1.841, 95% CI 1.252-2.705, <i>P</i> < 0.01). Furthermore, participants with pain duration > 3 years were significantly associated with olfactory impairment (OR 2.264, 95% CI 1.538-3.331, <i>P</i> < 0.001) and taste impairment (OR 2.070, 95% CI 1.335-3.209, <i>P</i> < 0.01). However, no statistically significant association was observed between pain duration and hearing impairment in any duration category.</p><p><strong>Conclusion: </strong>The results of this study suggest that individuals with longer chronic pain duration are at higher risk of sensory impairments, particularly visual, olfactory, and taste impairments. Timely and effective pain management may help reduce the risk of long-term sensory impairments.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1313-1323"},"PeriodicalIF":2.5,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11929418/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genicular Nerve Block as an Effective Treatment for Knee Pain: Addressing Variability and Enhancing Meta-Analysis Reliability [Letter].","authors":"Jia Liu, Chao Wen, Lichen Xu","doi":"10.2147/JPR.S523096","DOIUrl":"10.2147/JPR.S523096","url":null,"abstract":"","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1325-1326"},"PeriodicalIF":2.5,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11927568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Interscalene Brachial Plexus Block with Different Concentrations of Ropivacaine on Diaphragmatic Paralysis: A Randomized Controlled Study.","authors":"Ying Deng, Liwei Wang, Hua Zhang, Zhichao Xu, Ling Jiang, Yang Zhou","doi":"10.2147/JPR.S505238","DOIUrl":"10.2147/JPR.S505238","url":null,"abstract":"<p><strong>Background: </strong>This study aims to evaluate the degree of diaphragmatic paralysis by assessing diaphragmatic excursion and pulmonary function following an ultrasound-guided interscalene brachial plexus block with two different concentrations of ropivacaine (0.2% and 0.5%).</p><p><strong>Methods: </strong>Forty patients undergoing shoulder arthroscopic surgery were randomly assigned to receive ultrasound-guided interscalene brachial plexus block with 20 mL of either 0.2% or 0.5% ropivacaine. Diaphragmatic excursion (DE) and diaphragm thickening fraction (TF) were measured using M-mode ultrasound before and 30 minutes after the block. Pulmonary function was assessed using a portable spirometer. Additional outcomes included pain scores and the occurrence of adverse effects.</p><p><strong>Results: </strong>DE was significantly reduced 30 minutes after block in the 0.5% group compared to the 0.2% group (p<0.01), as well as the TF (p<0.01). Forced vital capacity (FVC) was also significantly reduced in the 0.5% group 30 minutes after block in the preparation room compared to the 0.2% group (p<0.001). Both 0.2% and 0.5% ropivacaine had similar effects in improving postoperative pain. There were no serious block-related complications in either group.</p><p><strong>Conclusion: </strong>0.2% ropivacaine may impair pulmonary function less than 0.5% ropivacaine. The clinical significance of these differences requires further investigation.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1341-1349"},"PeriodicalIF":2.5,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11928326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Commentary on \"Clinical Efficacy of Tuina Therapy for Acute Lumbar Sprain: A Bayesian Network Meta- Analysis Based on Randomized Controlled Trials\" [Response to Letter].","authors":"Jing Chen, Wu Li, Jiangshan Li","doi":"10.2147/JPR.S522148","DOIUrl":"https://doi.org/10.2147/JPR.S522148","url":null,"abstract":"","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1243-1245"},"PeriodicalIF":2.5,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11921790/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Cross-Sectional Study on Current Perioperative Pain Management and Nurses' Pain Management Self-Efficacy in China's Interventional Department.","authors":"Hao Zhang, Ya Meng, Xiaoxia Xu, Yanwei Li, Xue Li, Hongtao Hu, Lin Zheng, Xiaochun Hu","doi":"10.2147/JPR.S478935","DOIUrl":"10.2147/JPR.S478935","url":null,"abstract":"<p><strong>Objective: </strong>To critically evaluate the present status of perioperative pain management among nurses in interventional departments as well as to delineate the factors influencing the self-efficacy of pain management to provide a foundation for enhancing perioperative pain management practices.</p><p><strong>Methods: </strong>This was a descriptive cross-sectional study on 941 nurses from 24 Chinese provinces and municipalities. A questionnaire was conducted to examine the current pain management practices. Independent sample <i>t</i>-test and analysis of variance were used for inter-group comparison. Multiple linear regression analysis was done to analyze the influencing factors of pain management self-efficacy.</p><p><strong>Results: </strong>About 76.5% of the nurses in the interventional departments had undergone pain management training; however, more than one-third (37.6%) had not in the past two years. Merely 4.9% of nurses expressed confidence that their knowledge in pain management was sufficient to meet the demands the clinical practice. The foremost three areas of pain management information desired by the nurses in the intervention department were pain psychology (79.6%), pharmacological pain treatment (78.1%), and non-pharmacological pain interventions (77.4%). A majority (57.6%) of the nurses failed to assess the patients' comprehension and perspectives of analgesia, elements contributing to pain exacerbation or alleviation, and the outcomes of analgesic measures. The cumulative score for the pain self-efficacy questionnaire among nurses in the intervention department was 63.95±21.83. Multiple linear regression analysis revealed that variables such as the acquisition of pain knowledge, the frequency of pain training in the past two years, the ratio of evaluation tools employed for assessment, the prevalent utilization of multi-dimensional evaluation instruments, and professional course studies in academia were determinants influencing pain management self-efficacy.</p><p><strong>Conclusion: </strong>Perioperative pain management by interventional department nurses in China is unstandardized and lacks continuous education. Nursing administrators should create targeted training to boost pain assessment, prevention and treatment abilities.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1291-1303"},"PeriodicalIF":2.5,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11917163/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Use of Oral Celecoxib Preoperatively Reduces Risk of Delirium and Favors Functional Recovery in Elderly Patients with Femoral Neck Fracture: A Propensity Score-Matched Analysis\" [Letter].","authors":"Keyuan Fang, Shuyan Zhang, Xiaoxiao Ding","doi":"10.2147/JPR.S524682","DOIUrl":"10.2147/JPR.S524682","url":null,"abstract":"","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1241-1242"},"PeriodicalIF":2.5,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11917162/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Performance of Infrared Thermography, Quantitative Sudomotor Axonal Reflex Testing, and 3-Phase Bone Scintigraphy for Complex Regional Pain Syndrome Diagnosis: A Retrospective Observational Study.","authors":"Chan Noh, Jiyong Lee, Hye Young Choi, Eunhye Park, Yong Sup Shin, Boohwi Hong, Youngkwon Ko, Chahyun Oh, Sun Yeul Lee","doi":"10.2147/JPR.S474451","DOIUrl":"10.2147/JPR.S474451","url":null,"abstract":"<p><strong>Purpose: </strong>Complex regional pain syndrome (CRPS) diagnosis poses challenges due to the absence of an objective and definitive test. Although laboratory tests such as infrared thermography, quantitative sudomotor axonal reflex testing (QSART), and 3-phase bone scintigraphy have been considered diagnostic aids, their use remains controversial. This retrospective study aimed to elucidate the diagnostic validity and potential value of these modalities for the diagnosis of CRPS.</p><p><strong>Patients and methods: </strong>The Budapest criteria were used to diagnose CRPS, and infrared thermography, QSART, and 3-phase bone scintigraphy were performed as ancillary tests. Diagnostic performance was evaluated using receiver operating characteristic (ROC) curve analysis and measurement of sensitivity, specificity, and positive and negative likelihood ratios.</p><p><strong>Results: </strong>Of the 41 patients assessed, 26 (63.4%) were diagnosed with CRPS based on these criteria. Among the three tests, only infrared thermography demonstrated significant diagnostic performance (area under the ROC curve, 0.718; 95% confidence interval, 0.569-0.866; p = 0.003). Infrared thermography revealed a positive and negative likelihood ratio of 2.308 and 0.346, respectively, indicating clinically informative results. The three positive results exhibited the highest specificity (0.933) and positive predictive value (0.917).</p><p><strong>Conclusion: </strong>Among the three laboratory tests for CRPS, infrared thermography was the most useful. QSART and 3-phase bone scintigraphy did not show a significant diagnostic performance; however, combining the results of all three tests may provide additional diagnostic confidence in certain cases.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1305-1312"},"PeriodicalIF":2.5,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Physical Activity on Chronic Widespread Pain: Insights From Meta-Analysis and Two-Sample Mendelian Randomization.","authors":"Chongjie Yao, Yuchen Zhang, Sizheng Steven Zhao, Jun Ren, Pingping Sun, Lingjun Kong, Jiming Tao, Jingxian Li, Min Fang, Qingguang Zhu","doi":"10.2147/JPR.S505397","DOIUrl":"10.2147/JPR.S505397","url":null,"abstract":"<p><strong>Background: </strong>Chronic widespread pain (CWP) is a core symptom of fibromyalgia that is associated with significant morbidity and mortality. Despite the widespread recommendation for physical activity (PA) in management, the heterogeneity of PA prescriptions limits the in-depth evaluation of its efficacy. By triangulating clinical interventional evidence with human genetic evidence, the aim of this study was to investigate the role of influencing factors such as PA mode, course of treatment, and intensity on PA in the prevention and treatment of CWP.</p><p><strong>Methods: </strong>Ten international and regional databases were searched for articles published between January 2014 and July 2024. Randomized control trials with CWP or fibromyalgia as an entry criterion and PA as an intervention were included. Meta-analyses were performed using fixed- or random-effects models based on heterogeneity, and subgroup analyses were conducted. Mendelian randomization (MR) was used to estimate the effects of the genetic variants linked to PA intensity on CWP risk.</p><p><strong>Results: </strong>The analysis included 11 studies with 540 participants. PA effectively improved pain perception (MD: -1.47; 95% CI: -2.23, -0.72), depression (MD: -4.77; 95% CI: -7.40, -2.14), and overall quality of life (SMD: -1.43; 95% CI: -2.16, -0.69). MR analysis revealed that several PA intensities were associated with reduced susceptibility to CWP: walking for pleasure (OR: 0.950; 95% CI: 0.934-0.966), light do-it-yourself (DIY) (OR: 0.976; 95% CI: 0.961-0.992), strenuous sports (OR: 0.923; 95% CI: 0.880-0.967), and other exercises (OR: 0.957; 95% CI: 0.942-0.973).</p><p><strong>Conclusion: </strong>PA interventions are beneficial for reducing pain perception and mood disorders and enhancing the quality of life of patients with CWP. A treatment course of approximately three months is preferable, with Ba-Duan-Jin potentially more effective than other PAs, and high-intensity PA offers the most significant protective effect against CWP.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1275-1289"},"PeriodicalIF":2.5,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920634/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Evidence-Based Consensus for the Use of Neurostimulation for the Treatment of Non-Surgical Low Back Pain: The NEURON Group.","authors":"Timothy Ray Deer, Jason E Pope, Erika A Petersen, Rany T Abdallah, Kasra Amirdelfan, Nomen Azeem, Vishal Bansal, Kaku Barkoh, Kenneth B Chapman, Daniel R Denis, Michael J Dorsi, Alexander Escobar, Steven Michael Falowski, Rosa Amelia Garcia, Jonathan M Hagedorn, Robert D Heros, Whitney S James, Hemant Kalia, Todd Lansford, Mark N Malinowski, Suzanne Marie Manzi, Pankaj Mehta, Robert Z Moghim, Gregory Anthony Moore, Soriaya Lizette Motivala, Yeshvant A Navalgund, Raj G Patel, Julie G Pilitsis, Michael E Schatman, Philip Michael Shumsky, Natalie Holmes Strand, Nestor D Tomycz, James J Yue, Dawood Sayed","doi":"10.2147/JPR.S500342","DOIUrl":"10.2147/JPR.S500342","url":null,"abstract":"<p><strong>Introduction: </strong>The use of electrical neuromodulation has often been limited to those with previous back surgery, peripheral neuropathy, and complex regional pain syndrome. Many patients with severe intractable low back pain were thought to be candidates for spinal cord stimulation (SCS), dorsal root ganglion stimulation, or peripheral nerve stimulation but did not meet the criteria. Recently, additional high-level data has supported the use of SCS in non-surgical low back pain (NSLBP), and United States Food and Drug Administration approval has been granted. The American Society of Pain and Neuroscience (ASPN) executive committee realized an unmet need to develop criteria for patient selection for this specific patient population. This is a NEURON project (neuroscience, education, utilization, risk mitigation, optimal outcomes, and neuromodulation), a living guideline for evolving therapies and indications, and is focused on the use of neuraxial stimulation for the treatment of refractory pain.</p><p><strong>Methods: </strong>After board approval, the society accepted nominees for the project, with an emphasis on experience, publication, research, and diversity. The team created an outline for discussion, chose a grading system based on published guidelines, and created consensus points.</p><p><strong>Results: </strong>The evidence led to several consensus points to best guide patient selection based on the level of evidence and expert opinion. The results will lead to improved safety and efficacy in implanted patients, and to a new standard for best practices.</p><p><strong>Conclusion: </strong>The selection of patients for implantation in those who have NSLBP should be based on published literature, best practice, and expert opinion. This NEURON project will allow for regular updates to create a living guideline that will allow for better assimilation of information to improve safety and efficacy going forward.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1247-1274"},"PeriodicalIF":2.5,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11917438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Bilateral Erector Spinae Plane Block on the Gastrointestinal Function in Patients Undergoing Traumatic Lumbar Spine Fracture surgery: A Retrospective Study.","authors":"Meizhu Zhao, Mingyang Gao, Xin Zhang, Qi Zhou, Peixia Yu, Chunxiao Liu, Xueyin Song, Xin Shan, Jianglong Dong, Zhihua Li, Qiujun Wang","doi":"10.2147/JPR.S492380","DOIUrl":"10.2147/JPR.S492380","url":null,"abstract":"<p><strong>Purpose: </strong>This retrospective study aimed to explore the effect of erector spinae plane block (ESPB) on the gastrointestinal function in patients after traumatic lumbar fracture surgery and the effects of different levels of block approach.</p><p><strong>Patients and methods: </strong>Clinical data were retrospectively analyzed from electronic medical records of patients who underwent traumatic lumbar spine fracture surgery (September 2022-June 2023). Eligible patients were divided into three groups: group L (bilateral ESPB at L3 level), group T (bilateral ESPB at T12 level) and group C (no block). The primary outcomes were the incidence and the time of occurrence postoperative bloating. We also recorded the time of the first flatus and bowel movement, postoperative nausea and vomiting (PONV), gastrointestinal medications, enema, intraoperative opioid dosage, number of rescue analgesia within 48 h postoperatively, visual analogue scale (VAS) scores at 24 h and 48 h postoperatively, inflammatory mediators, complications and hospital length of stay (LOS).</p><p><strong>Results: </strong>145 patients were included, including 32 in group L, 33 in group T and 80 in group C. Patients in group L and T experienced less bloating compared to group C (<i>P</i> < 0.05). Patients in group T presented bloating significantly later than group L (log rank <i>P</i> < 0.0167). Patients in group L and group T had a significantly shorter time to first flatus and bowel movement, lower incidence of PONV, gastrointestinal medications and enema, and a lower dose of opioid and VAS scores at 24 h postoperatively compared to group C (all <i>P</i> < 0.05), the difference between group L and T was not statistically significant.</p><p><strong>Conclusion: </strong>Bilateral ESPB improved postoperative gastrointestinal function in patients with traumatic lumbar spine fracture, where the T12 level of ESPB was more favorable than the L3 level.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1231-1239"},"PeriodicalIF":2.5,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11912902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}