Journal of Pain Research最新文献

{"title":"Safety and Effectiveness of Electroacupuncture During Colon Endoscopic Submucosal Dissection: A Randomized Controlled Trial.","authors":"Jiamin Zhang, Hao Zhang, Junfei Zheng, Cong Niu, Shu Zhu, Haiqing Hu, Ye Lu, Meihua Zhu","doi":"10.2147/JPR.S501941","DOIUrl":"10.2147/JPR.S501941","url":null,"abstract":"<p><strong>Background: </strong>Endoscopic treatment of early colon neoplasms has evolved as a valid and less traumatic alternative to surgical resection. It can usually be performed with sedation on an outpatient basis. The present study was performed to determine the safety and effectiveness of electroacupuncture (EA) versus propofol sedation during endoscopic submucosal dissection (ESD) for early colon neoplasm.</p><p><strong>Methods: </strong>A total of 150 adult outpatients undergoing ESD were selected and divided into the EA combined with propofol group (EP group), remifentanil combined with propofol group (RP group), and propofol group (SP group), with 50 patients in each group. All patients received standard sedation with propofol. Acupuncture was performed before intravenous propofol injection in the EP group. A density wave of 1-3 mA, 2/100 hz current was administered for 20 min before the induction of anesthesia. The effectiveness of sedation was measured by satisfaction levels, and pain and sedation scores were measured by questionnaires. Respiratory and hemodynamic complications were monitored and compared as indices of safety.</p><p><strong>Results: </strong>Demographic data were comparable among the three groups. The total dose of propofol and the percentage of body movement in the EP group were lower than in the SP and RP groups (<i>P</i><0.01). The incidence of hypotension and bradycardia in the SP and RP groups was higher than in the EP group. Patients who received the EA intervention showed a significant reduction in hypoxemia. The endoscopists felt that the procedure was more favorable in the EP group, but, there was no significant difference of patient satisfaction scores among three groups.</p><p><strong>Conclusion: </strong>Sedation with EA is effective and safe for patients undergoing ESD, and could improve the satisfaction levels of patients and gastroendoscopists.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1221-1229"},"PeriodicalIF":2.5,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Evaluation of Reference Values of Plasma and Effect-Site Concentrations of Propofol and Remifentanil During Extubation in Patients Who Had Hysteroscopy Procedures.","authors":"Yu Wei, Jianwei Wang, Zifeng Xu, Rui Ma","doi":"10.2147/JPR.S486147","DOIUrl":"https://doi.org/10.2147/JPR.S486147","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to assess the correlation of plasma concentration (Cp) and effect-site concentration (Ce) of propofol and remifentanil with level of consciousness and evaluate their reference values during extubation in patients scheduled day-case operative hysteroscopy under propofol-remifentanil anesthesia.</p><p><strong>Methods: </strong>Propofol (Marsh model) and remifentanil (Minto model) were simultaneously administered using a target-controlled infusion (TCI) pump for the induction and maintenance of anesthesia. The Cp and Ce of propofol (PCp and PCe) and remifentanil (RCp and RCe) before anesthesia induction, at the end of surgery, and at the time of extubation were respectively recorded. Predictive performance was assessed using the jackknife method.</p><p><strong>Results: </strong>At the time of extubation, PCp was 1.17 ± 0.168 (95% CI: 1.14-1.20 μg/mL), PCe was 1.7 ± 0.212 (95% CI: 1.65-1.74 μg/mL), RCp was 0.769 ± 0.12 (95% CI: 0.75-0.79μg/mL), and RCe was 0.972 ± 0.179 (95% CI: 0.94 -1.01 μg/mL). The P_k values of PCp, PCe, RCp and RCe were 0.999, 0.993, 1.00 and 0.995, separately. Postoperative decreases in PCp (r = 0.089, p < 0.001), PCe (r = 0.087, p= 0.001), RCp (r = 0.072, p < 0.000) and RCe (r = 0.077, p < 0.001) were significantly correlated with the recovery time.</p><p><strong>Conclusion: </strong>PCp, PCe, RCp and RCe, together with OAA/S Scale and the recovery of spontaneous respiration might be potential reference indicators for extubation in day-surgery hysteroscopy following general anesthesia using TCI.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1211-1219"},"PeriodicalIF":2.5,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fu's Subcutaneous Needling Combined with Kinematic Acupuncture versus Electroacupuncture in the Treatment of Cervical Spondylotic Radiculopathy: A Randomized Controlled Trial.","authors":"Yingtong Lin, Wanyi Hong, Lili Sui, Qian Jiang, Ganghui Jiang, Weixin Yan, Nenggui Xu, Rui Zhang","doi":"10.2147/JPR.S498728","DOIUrl":"10.2147/JPR.S498728","url":null,"abstract":"<p><strong>Background: </strong>Degenerative Cervical Myelopathy (DCM) is an overarching term that encompasses a broad spectrum of degenerative conditions affecting the cervical spine. Cervical Spondylosis Radiculopathy (CSR) represents a prevalent yet particularly severe type within the broader spectrum of Degenerative Cervical Myelopathy (DCM). Currently, conservative treatments, such as acupuncture, traction, physical therapy, and medication, are the standard methods used. As a widely applied physical therapy for musculoskeletal disease, Fu's Subcutaneous Needling (FSN) therapy could be considered when choosing treatment interventions for complement. Electroacupuncture, a commonly used acupuncture treatment, has been proven effective by multiple studies. The comparative analysis with electroacupuncture is specifically aimed at assessing the potential advantages and therapeutic efficacy of FSN therapy in the management of CSR. This is particularly pertinent in instances where conventional conservative interventions and traditional acupuncture techniques may fall short in providing adequate symptom relief.</p><p><strong>Methods: </strong>The study was a single-centered study without blinding. 80 eligible patients were randomly assigned into two groups, with 40 in each group. The study group received FSN combined with Kinematic acupuncture, the control group received electroacupuncture treatment.</p><p><strong>Results: </strong>The results after treatment demonstrated that the study group had significantly higher scores in VAS (<i>P</i>=0.001), NPQ (<i>P</i>=0.000), NDI (<i>P</i>=0.000), TY (<i>P</i>=0.000), SF-36 (<i>P</i>=0.000), Hand-numbness (<i>P</i>=0.004), total effective rate (<i>P</i>=0.004) and Analgesic effect time (<i>P</i>=0.001) compared to the control group. The follow-up results also indicated that the experimental group outperformed the control group in VAS (<i>P</i>=0.000), NPQ (<i>P</i>=0.000), NDI (<i>P</i>=0.000), TY (<i>P</i>=0.000), SF-36 (<i>P</i>=0.000), however, the results of Hand-numbness scoring showed no significant statistical difference between both two groups (<i>P</i>=0.302), neither did Relieve duration (<i>P</i>=0.562).</p><p><strong>Conclusion: </strong>In general, Fu's Subcutaneous Needling combined with Kinematic acupuncture method is more effective in relieving symptoms and promoting recovery of CSR.</p><p><strong>Trail registration: </strong>The clinical trial has been registered at the Chinese Clinical Trial Registry (NO. ChiCTR2300068507).</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1191-1204"},"PeriodicalIF":2.5,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11911824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Local Structural Indices Changes During Different Periods of Postherpetic Neuralgia: A Graphical Study in Structural Covariance Networks.","authors":"Jiaxin Xiong, Lili Gu, Xiaofeng Jiang, Hongmei Kuang, Huiting Lv, Zihan Li, Yangyang Xie, Qing Luo, Jian Jiang","doi":"10.2147/JPR.S515047","DOIUrl":"10.2147/JPR.S515047","url":null,"abstract":"<p><strong>Purpose: </strong>In this study, we aim to explore the changes in network graph theory indices of structural covariance networks (SCNs) in PHN patients with different disease durations.</p><p><strong>Patients and methods: </strong>High-resolution T1 magnetic resonance images were collected from 109 subjects. We constructed SCNs based on cortical thickness data and analyzed the changes in global and regional network measures of PHN patients and herpes zoster (HZ) patients, and get hubs of each group.</p><p><strong>Results: </strong>(1) PHN patients with a disease duration >6 months had reduced global efficiency (P=0.035) and increased characteristic shortest path length (P=0.028). (2) Nodal efficiency of the right pars opercularis was greater in both HZ and PHN patients with a disease duration of 1 to 3 months (P<0.001); in PHN patients with a disease duration > 6 months, the nodal degree of the left pars triangularis and nodal efficiency of the right middle temporal gyrus were greater (P<0.001). (3) The right supramarginal gyrus was the common hub of healthy controls (HCs) and HZ patients, the right pars opercularis was the common hub of HZ patients and PHN patients with a disease duration of 1 to 3 months, and the bilateral superior frontal gyrus was the common hub of HZ patients and PHN patients with a disease duration >6 months.</p><p><strong>Conclusion: </strong>There have changes in SCN indices in PHN patients with different disease durations. PHN patients with a disease duration >6 months had increased SCN integration and diminished information transfer capability between nodes, which complemented the topological properties of previous PHN networks. Eglobal and Lp can be considered as potential imaging markers for future clinical restaging of PHN.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1175-1187"},"PeriodicalIF":2.5,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11911238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Acupoint Selection Rules for Guasha Treatment of Primary Headaches Based on Data Mining [Letter].","authors":"Tianai Shi, Zili Liu","doi":"10.2147/JPR.S522743","DOIUrl":"10.2147/JPR.S522743","url":null,"abstract":"","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1209-1210"},"PeriodicalIF":2.5,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910046/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addressing the Future of Pain Medicine Training: Redevelopment of Post-Doctoral Training as an Even More Imperative Standard in Latin America.","authors":"Rodrigo Diez-Tafur, Victor M Silva-Ortiz, Carlos Guerrero-Nope, Juan Felipe Vargas-Silva, Camila Lobo, Fabricio Dias Assis, Michael E Schatman, Christopher L Robinson, Sudhir Diwan, Ricardo Plancarte-Sanchez","doi":"10.2147/JPR.S522440","DOIUrl":"https://doi.org/10.2147/JPR.S522440","url":null,"abstract":"","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1173-1174"},"PeriodicalIF":2.5,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910164/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143648800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electroacupuncture Alleviates Neuropathic Pain and Negative Emotion in Mice by Regulating Gut Microbiota [Letter].","authors":"Ruoxuan Wang","doi":"10.2147/JPR.S523215","DOIUrl":"https://doi.org/10.2147/JPR.S523215","url":null,"abstract":"","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1207-1208"},"PeriodicalIF":2.5,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Commentary on \"Analysis of Factors Related to Throat Soreness After Painless Gastroscopy: A Single-Center Study\" [Letter].","authors":"Wei Fu, Junlong Zhao, Yan Geng","doi":"10.2147/JPR.S516552","DOIUrl":"https://doi.org/10.2147/JPR.S516552","url":null,"abstract":"","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1205-1206"},"PeriodicalIF":2.5,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910045/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143648231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Adding Nalbuphine to Ropivacaine on Postoperative Analgesia of Erector Spinae Plane Block [Letter].","authors":"Dan-Feng Wang, Yan-Hua Guo, Fu-Shan Xue","doi":"10.2147/JPR.S522137","DOIUrl":"https://doi.org/10.2147/JPR.S522137","url":null,"abstract":"","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1159-1160"},"PeriodicalIF":2.5,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effectiveness of Acupuncture on Myofascial Trigger Points Versus Traditional Chinese Medicine Acupoints for Treating Plantar Fasciitis With Low Back Pain: A Study Protocol for a Randomised Clinical Trial [Letter].","authors":"Riya Kalra, Kanu Goyal, Manu Goyal","doi":"10.2147/JPR.S521294","DOIUrl":"https://doi.org/10.2147/JPR.S521294","url":null,"abstract":"","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"18 ","pages":"1189-1190"},"PeriodicalIF":2.5,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}