Journal of Pain Research最新文献

{"title":"Erratum: Efficacy and Safety of Rimegepant 75 Mg Oral Tablet, a CGRP Receptor Antagonist, for the Acute Treatment of Migraine: A Randomized, Double-Blind, Placebo-Controlled Trial [Corrigendum].","authors":"","doi":"10.2147/JPR.S499096","DOIUrl":"https://doi.org/10.2147/JPR.S499096","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.2147/JPR.S453806.].</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4085-4086"},"PeriodicalIF":2.5,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11625503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment Algorithms for Continuous Low-Level Heat Wrap Therapy for the Management of Musculoskeletal Pain: An Italian Position Paper.","authors":"Giuseppe Ventriglia, Massimiliano Franco, Alberto Magni, Fabrizio Gervasoni","doi":"10.2147/JPR.S452661","DOIUrl":"10.2147/JPR.S452661","url":null,"abstract":"<p><p>Musculoskeletal pain (MSP), which impacts bones, muscles, tendons, and ligaments, is a substantial worldwide pain disorder, characterized by muscle soreness, fatigue, inflammation, muscle spasms, sleep disruptions, and functional limitations. MSP is predominantly managed within the primary care setting. Recent consensus recognizes that heat therapy (HT) may provide potential benefits, especially in treating chronic MSP. To develop shared algorithms for the treatment of MSP through local superficial HT (SHT) using continuous low-level heat wrap therapy, a four-member board of experts was designated. Three anatomical sites have been deemed of particular interest regarding potential response to exogenous SHT. Neck and shoulder pain are commonly attributed to traumatic experiences, muscle spasms, postural defects, or poor posture as common potential causes. HT may be helpful for painful contractures, although treatment should be limited in duration to prevent instability. Low back pain, the leading cause of disability, may have either specific or non-specific etiology. SHT, physical therapy, instrumental therapy, manual therapy, therapeutic exercise, motor activity, and trunk orthoses are all potential treatment options. SHT should be considered in chronic degenerative disc disease, non-specific LBP with muscle spasm or contracture, postural and overuse myalgia, and osteoarthritis (OA), excluding the inflammatory phase. Assessment of knee pain includes both a review of the patient's medical history and a careful physical examination. SHT of the knee should be considered in case of muscle spasms, overuse pathology, early OA, and indirect muscle lesions. Patients who receive SHT may experience a reduction in pain, restoration of muscle strength, loosening of stiffness, and an overall improvement in their quality of life. This expert opinion proposes shared algorithms for MSP treatment via local SHT with the aiming to provide practical guidance on its proper application, highlighting specific potentialities as well as contraindications.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4075-4084"},"PeriodicalIF":2.5,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11625227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Commentary on \"Association Between Oral Behaviors and Painful Temporomandibular Disorders: A Cross-Sectional Study in the General Population\" [Response to Letter].","authors":"Shuyuan Zhang, Ruonan Sun, Jiarui Si, Xin Xiong","doi":"10.2147/JPR.S507568","DOIUrl":"10.2147/JPR.S507568","url":null,"abstract":"","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4073-4074"},"PeriodicalIF":2.5,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11624681/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Commentary on \"Association Between Oral Behaviors and Painful Temporomandibular Disorders: A Cross-Sectional Study in the General Population\" [Letter].","authors":"Junhao Fang, Yanlin Wu, Hongxuan Tong","doi":"10.2147/JPR.S504656","DOIUrl":"10.2147/JPR.S504656","url":null,"abstract":"","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4071-4072"},"PeriodicalIF":2.5,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622679/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cervical Rotation-Traction Manipulation for Cervical Radiculopathy: A Systematic Review and Meta-Analysis of Randomized Control Trials.","authors":"Tianxiao Feng, Xu Wang, Hanmei Bu, Kai Sun, Xiaokuan Qin, Rong Xie, Liguo Zhu, Xu Wei","doi":"10.2147/JPR.S481803","DOIUrl":"10.2147/JPR.S481803","url":null,"abstract":"<p><strong>Background: </strong>Cervical radiculopathy (CR) is a common musculoskeletal disorder worldwide. Cervical rotation-traction manipulation (CRTM) is one of the representative technique in traditional Chinese orthopedics.</p><p><strong>Objective: </strong>This systematic review and meta-analysis aims to evaluate the effectiveness and safety of CRTM in treating CR.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted through eight databases to identify the relevant randomized controlled trials (RCTs) from inception to December 2023. The primary outcome was the Visual Analogue Scale (VAS). The secondary outcomes included Neck Disability Index (NDI), Japanese Orthopaedic Association (JOA), Cervical Range of Motion, cervical curvature, and adverse reactions and events. Two researchers independently screened literature, extracted data, and assessed the risk of bias in included studies. Meta-analysis was performed using RevMan 5.4 and Stata 15.0 software, and the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) system was used to assess the quality of the evidence.</p><p><strong>Results: </strong>A total of 9 RCTs involving 904 patients were included. The results indicated that CRTM significantly reduced VAS scores compared to control groups with low-quality evidence [<i>n</i>=534, WMD=-1.27, 95% CI (-1.66, -0.87), <i>p</i><0.00001, <i>I²</i>=59%]. Subgroup analysis showed that differences in control group categories, sample sizes, and intervention durations may contribute to the observed heterogeneity. Besides, CRTM significantly improved cervical range of motion of lateral flexion and rotation with very low-quality evidence. However, no statistically significant differences were observed in NDI scores, JOA scores, or cervical curvature between CRTM and control groups. No adverse reactions and events related to CRTM were reported in included studies, demonstrating its high safety.</p><p><strong>Conclusion: </strong>Cervical rotation-traction manipulation appears to be an effective and safe option for managing cervical radiculopathy, significantly improving pain and cervical mobility. However, further high-quality randomized controlled trials and methodological studies should be conducted to reinforce the evidence base for its clinical practice.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4055-4070"},"PeriodicalIF":2.5,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum: Comprehensive Bibliometric Analysis of Research Articles on Post-Herpetic Neuralgia and Varicella-Zoster Virus: A 20-Year Review (2003-2022) [Corrigendum].","authors":"","doi":"10.2147/JPR.S508903","DOIUrl":"https://doi.org/10.2147/JPR.S508903","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.2147/JPR.S432485.].</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4053-4054"},"PeriodicalIF":2.5,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11612558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Efficacy of Liposomal Bupivacaine in Thoracic Surgery: A Systematic Review and Meta-Analysis.","authors":"Ruisong Gong, Gang Tan, Yuguang Huang","doi":"10.2147/JPR.S492117","DOIUrl":"10.2147/JPR.S492117","url":null,"abstract":"<p><strong>Purpose: </strong>Patients undergoing thoracic surgery suffer from severe postoperative pain, and a series of complications will occur if there is no effective analgesic treatment. Liposomal bupivacaine (LB) is a novel multivesicular formulation with up to 72 hours of analgesia, which can be used in thoracic surgery. This meta-analysis aimed to evaluate the efficacy of LB in improving recovery in patients undergoing thoracic surgery compared with non-liposomal local anesthetics.</p><p><strong>Patients and methods: </strong>A literature search was conducted using PubMed, Cochrane Library, Embase, and Web of science, and to identify all observational or retrospective studies and randomized controlled trials (RCTs) from inception to December 2023. The primary outcome was the in-hospital postsurgical opioid consumption in morphine milligram equivalents (MMEs). Secondary outcomes included 24-hour postoperative MMEs, postoperative pain score in the first 24 and 48 hours, hospital length of stay (LOS), time to first ambulation, readmission, and perioperative complications. RevMan 5.3 was used for the data analysis.</p><p><strong>Results: </strong>A total of 10 studies were included in the analysis, of which eight were observational or retrospective analyses and two were RCTs. There were no significant differences in the postoperative MMEs, pain score, LOS, time to first ambulation, readmission, and perioperative complications.</p><p><strong>Conclusion: </strong>According to this meta-analysis, LB was found to be not superior to non-liposomal local anesthetics for analgesic and functional outcomes in thoracic surgery.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4039-4051"},"PeriodicalIF":2.5,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Pain Medicine Training in Latin America.","authors":"Rodrigo Díez-Tafur, Matthew Slitzky, Carlos Guerrero-Nope, Ricardo Plancarte-Sanchez, Jesús Medina-Rascon, Carlos Eduardo Restrepo-Garces, Juan Felipe Vargas-Silva, Carlos Marcelo de Barros, Fabricio Dias Assis, Camila Lobo, Andrés Rocha-Romero, Juan Pablo Paladino, Wendy Rojas-Gareca, César R Carcamo-Quezada, Juan Carlos Sosa Nicora, Angie Navarrete, Soraya Mariuxi Cruz Loor, Claudia B Cruz-Ayala, Lisbeth Godinez Ortiz, Sudhir Diwan, Michael E Schatman, Christopher L Robinson, Victor M Silva-Ortiz","doi":"10.2147/JPR.S504547","DOIUrl":"https://doi.org/10.2147/JPR.S504547","url":null,"abstract":"","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4033-4038"},"PeriodicalIF":2.5,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Erector Spinae Plane Blocks on Pain Management and Postoperative Outcomes in Patients with Chronic Pain Undergoing Spine Fusion Surgery: A Retrospective Cohort Study.","authors":"Krizia Amoroso, James A Beckman, Jiaqi Zhu, Erika Chiapparelli, Ali E Guven, Jennifer Shue, Andrew A Sama, Federico P Girardi, Frank P Cammisa, Alexander P Hughes, Ellen M Soffin","doi":"10.2147/JPR.S483144","DOIUrl":"https://doi.org/10.2147/JPR.S483144","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the impact of bilateral ultrasound-guided erector spinae plane blocks (ESPBs) on pain and opioid-related outcomes in a surgical population with chronic pain.</p><p><strong>Methods: </strong>A retrospective, observational cohort study. Clinical data were extracted from the electronic medical records of patients who underwent lumbar fusion (February 2018 - July 2020). Eligible patients had a confirmed history/diagnosis of chronic pain starting >3 months before surgery and received either bilateral ESPBs or no ESPBs. Patients were matched on demographic variables (sex, age, race, BMI, ASA Classification, and preoperative opioid use) in a 1:1 ratio. The primary outcome was median opioid consumption (morphine equivalent dose, MED) 24 hours post-surgery (hydromorphone iv-PCA and oral). Secondary outcomes included Numeric Rating Scale (NRS) pain scores, opioid consumption up to 48 hours post-surgery, and hospital length of stay (LOS). Group differences were analyzed using bivariable and multivariable regression.</p><p><strong>Results: </strong>Of 72 patients, 36 received ultrasound-guided ESPBs and 36 did not. Baseline demographics showed no significant differences. On bivariable analysis, ESPBs were associated with significantly lower 24-hour opioid consumption (79 mg MED vs 116 mg MED, p=0.024) and shorter LOS (82 hours, 95% CI 51-106 vs 126 hours, 95% CI 101-167, p<0.001). No significant differences in NRS pain scores were found up to 48 hours post-surgery. Multivariable analysis confirmed significant reductions in 24-hour opioid consumption (-44, 95% CI -1.06 - -87.55, p=0.044), IV-PCA use (-22, 95% CI -1.59 - -56.77, p=0.038), and LOS (-38, 95% CI -10.074 - -66.22, p=0.008) in the ESPB group without differences in NRS pain scores.</p><p><strong>Conclusion: </strong>ESPBs were associated with statistically and clinically significant reductions in 24-hour opioid consumption and LOS, without differences in NRS pain scores after spinal fusion in a chronic pain surgical cohort. Given these effects, patients with chronic pain may disproportionately benefit from ESPBs for spine surgery.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4023-4031"},"PeriodicalIF":2.5,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The CT-Imaging Location of Lumbar 3 Sympathetic Radiofrequency Thermocoagulation for Sympathetic-Related Diseases Therapy.","authors":"Ruxiang Wang, Zhuoyue Gao, Ling Ma","doi":"10.2147/JPR.S473078","DOIUrl":"https://doi.org/10.2147/JPR.S473078","url":null,"abstract":"<p><strong>Purpose: </strong>The location characteristic of the lumbar 3 sympathetic trunk under Computed Tomography (CT) was discovered through 106 cases, imaging analysis after successful lumbar 3 sympathetic radiofrequency thermocoagulation operations serving the clinic and reducing the operation time.</p><p><strong>Methods: </strong>There are 113 patients underwent bilateral L3 lumbar sympathetic thermal radiofrequency procedures in our hospital from January 2017 to January 2021, with 106 cases of successful procedure. Four operation image distances were measured: 1. The left/right distances between the needle tip (the location of needle tip was the sympathetic trunk at the same CT scan level) and the transverse process of the lumbar spine (D1l/D1r); 2. The left/right distances between the needle tip and the medial margin of the psoas major (D2l/D2r); 3. The left/right vertical distances between the needle tip and vertebral body (D3l/D3r); 4. The left/right vertical distances between ureter and vertebral body (D4l/D4r). The Perfusion Index (PI) and the plantar temperature were monitored and recorded before and after the treatment (the higher PI value and the plantar temperature indicated successful procedure). After the procedure, the patients were followed up one day, one week, two months and six months for satisfaction, complications and recurrences.</p><p><strong>Results: </strong>The left distance (D1l) from the needle tip to the transverse costal process being 4.444±0.7668mm, longer than the right side (D1r, P<0.001). The left distance (D2l) being 1.260±0.4261mm longer than the right side (D2r, P=0.0039). The left distance (D3l) was 1.634±0.2597mm longer than the right side (D3r, P<0.0001). The D4l and D4r both having a long distance far from needle tips (P=0.665). Both the left and right temperature and PI increased have statistical significances after treatment (P<0.0001). There were 2(1.77%) cases experiencing numbness of big thighs, and 9(7.96%) cases of compensatory hyperhidrosis, with only 3 (2.65%) cases reverting to the original state six months later.</p><p><strong>Conclusion: </strong>Lumbar sympathetic radiofrequency thermocoagulation is a valid treatment option for sympathetic-related disease in lower limbs, and based on our study data CT-guided percutaneous puncture lumbar sympathectomy can easy be proceed and gained more persistent effection, the left needle distance more deeper than the right side, the distance from the left side should be far from vertebral body than the right side. The distance between the needle body and the vertebral body on the left side is far away from the right side.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4011-4022"},"PeriodicalIF":2.5,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}