Journal of Pain ResearchPub Date : 2024-12-10eCollection Date: 2024-01-01DOI: 10.2147/JPR.S489296
Yujun He, Yachao Wu, Xiaojun Li
{"title":"Analysis of Acupoint Selection and Combinations in Acupuncture Treatment of Migraine: A Protocol for Data Mining.","authors":"Yujun He, Yachao Wu, Xiaojun Li","doi":"10.2147/JPR.S489296","DOIUrl":"10.2147/JPR.S489296","url":null,"abstract":"<p><strong>Background: </strong>Migraine is a prevalent neurological condition that causes significant disability and has a profound impact on sufferers' ability to work and their overall quality of life. The efficacy of acupuncture in the treatment of migraines has been confirmed via extensive clinical research. However, because each acupoint generates various analgesic processes, and different acupuncture physicians select different acupoints, there is still uncertainty regarding the optimal acupoint selection.</p><p><strong>Objective: </strong>Our purpose is to conduct the initial thorough data mining analysis to determine the optimal acupoint selection and combinations for the treatment of migraines.</p><p><strong>Methods: </strong>We will conduct a search of eight electronic bibliographic databases (PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Wanfang Database, Chinese Biomedical Literature Database, and Chongqing VIP Database) from the inception of the databases to July 2024. Clinical trials that evaluate the efficacy of acupuncture therapy in migraine management will be chosen. Literature will be rigorously reviewed in accordance with inclusion and exclusion criteria, and pertinent data will be extracted for analysis. Excel 2021 will be utilized to conduct descriptive statistics. SPSS Modeler 14.1 will be employed to conduct the association rule analysis. SPSS Statistics 26.0 will be employed to conduct exploratory factor analysis, cluster analysis, and decision tree analysis.</p><p><strong>Results: </strong>This study aims to investigate the optimal acupoint selection and combinations for people suffering from migraines.</p><p><strong>Conclusion: </strong>Our research will offer empirical support for the efficacy and possible therapeutic recommendations of acupoint application in treating migraine patients, facilitating collaborative decision-making between physicians and patients.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4149-4157"},"PeriodicalIF":2.5,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11645895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of Pain ResearchPub Date : 2024-12-10eCollection Date: 2024-01-01DOI: 10.2147/JPR.S487712
Qing Zhao Ruan, Daniel J Pak, David E Reece, Rohan Jotwani, Sean Li, Moises Dominguez, Alan David Kaye, R Jason Yong, Abdulrazaq Albilali, Sadiq Bhayani, Jamal Hasoon, Michael E Schatman, Jun Beom Ku, Thomas T Simopoulos, Sait Ashina, Christopher L Robinson
{"title":"The Efficacy of Botulinum Toxin Use in Service Members and Veterans with Migraine and Post-Traumatic Headache Disorders: A Scoping Review.","authors":"Qing Zhao Ruan, Daniel J Pak, David E Reece, Rohan Jotwani, Sean Li, Moises Dominguez, Alan David Kaye, R Jason Yong, Abdulrazaq Albilali, Sadiq Bhayani, Jamal Hasoon, Michael E Schatman, Jun Beom Ku, Thomas T Simopoulos, Sait Ashina, Christopher L Robinson","doi":"10.2147/JPR.S487712","DOIUrl":"10.2147/JPR.S487712","url":null,"abstract":"<p><strong>Objective: </strong>To delineate the trend of use of botulinum toxin, including onabotulinum toxinA (OTA), in active military personnel and veterans with the diagnoses of migraine and post-traumatic headache (PTH) and describe the efficacy of botulinum toxin administration.</p><p><strong>Background: </strong>Service members and veterans represent a unique population in the medical management of headache disorders, particularly migraine. They exhibit higher susceptibility to pain of greater intensity and longer durations, possibly due to their history of exposure to combat, trauma, and the associated psychological stresses. Given the burden and morbid nature of these headache disorders, prophylactic measures to reduce migraine attacks and disability are imperative. Specifically, the use of OTA for migraine prophylaxis has been well validated in chronic migraine.</p><p><strong>Methods: </strong>The scoping review conformed to guidelines delineated by Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). The databases Medline, Embase, and Google Scholar were accessed for our literature search, and the time frame of the search was set from database inception to April 1, 2024.</p><p><strong>Results: </strong>A total of 8 articles meeting the inclusion criteria were obtained after screening a total of 43 papers. Studies were primarily conducted in the United States (87.5%), with a single article published on veterans from Taiwan. Study types were mainly retrospective chart reviews with the exception of 2 randomized controlled trials. Chronic migraine was the most common headache diagnosis examined, being assessed in 6 studies, followed by PTH, which was represented in the remaining 2 studies.</p><p><strong>Conclusion: </strong>The occupational exposure of service members appears to result in a higher incidence of headache disorders such as chronic migraine and PTH, which are amenable to preventative management such as that with botulinum toxin. Despite its effectiveness, the use of botulinum toxin in treating headaches and craniofacial pain in service members remains under-researched, warranting further exploration in this population, specifically.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4177-4186"},"PeriodicalIF":2.5,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11646469/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of Pain ResearchPub Date : 2024-12-10eCollection Date: 2024-01-01DOI: 10.2147/JPR.S507795
Aili Fang, Yuxuan Miao, Han Wang
{"title":"A Commentary on \"Pain Reduction and Improved Vascular Health Associated with Daily Consumption of an Anti-Inflammatory Dietary Supplement Blend\" [Letter].","authors":"Aili Fang, Yuxuan Miao, Han Wang","doi":"10.2147/JPR.S507795","DOIUrl":"10.2147/JPR.S507795","url":null,"abstract":"","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4197-4198"},"PeriodicalIF":2.5,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11645945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of Pain ResearchPub Date : 2024-12-10eCollection Date: 2024-01-01DOI: 10.2147/JPR.S485548
Qing Zhao Ruan, Daniel J Pak, Amitabh Gulati, Moises Dominguez, Sudhir Diwan, Jamal Hasoon, Timothy R Deer, R Jason Yong, Abdulrazaq Albilali, Amanda Macone, Sait Ashina, Christopher L Robinson
{"title":"Scoping Review: The Effects of Interrupted Onabotulinumtoxin A Treatment for Chronic Migraine Prevention During the COVID-19 Pandemic.","authors":"Qing Zhao Ruan, Daniel J Pak, Amitabh Gulati, Moises Dominguez, Sudhir Diwan, Jamal Hasoon, Timothy R Deer, R Jason Yong, Abdulrazaq Albilali, Amanda Macone, Sait Ashina, Christopher L Robinson","doi":"10.2147/JPR.S485548","DOIUrl":"10.2147/JPR.S485548","url":null,"abstract":"<p><strong>Objective: </strong>To systematically examine the literature on the clinical consequences of inadvertent delays in scheduled onabotulinumtoxin A (OTA) therapy for chronic migraine during the COVID-19 pandemic and assess recommendations when access to OTA is limited.</p><p><strong>Background: </strong>The coronavirus (COVID-19) pandemic was unprecedented in its impact on the global medical community. Most healthcare institutions in the United States (US) and the world had begun significantly limiting elective procedures, undermining management of many debilitating chronic conditions. OTA injections, were similarly involuntarily postponed, leading to significant setbacks in symptom control.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted on databases of Medline and Embase with search timeframe defined as the point of database inception to March 1st, 2024, and the search was performed on March 2nd, 2024. The search strategy was independently formulated by two authors (QR and CR) and was reviewed and approved by all authors of the article after appropriate amendments.</p><p><strong>Results: </strong>A total of nine articles met the defined inclusion criteria. They collectively demonstrated marked delays in OTA treatment with decline in migraine symptom control measured in the form of migraine intensity, frequency, as well as patient satisfaction in disease management. Quality of care in the form of follow-ups also appeared compromised. Alternative strategies of telemedicine and the administration of calcitonin gene-related peptide monoclonal antibodies (CGRP mAb) were adopted in place of conventional treatment.</p><p><strong>Conclusion: </strong>The COVID-19 pandemic had caused marked clinical deterioration in the migraine patient populations across US, Europe, and the Middle East. Strategies employed to circumvent this limitation included the adoption of remote consultation via telemedicine as well as the use of pharmacological agents such as CGRP antagonists. In the event of a reoccurrence of a worldwide pandemic, strategies should be implemented to prevent the cessation of needed treatment for those suffering from chronic migraine.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4163-4176"},"PeriodicalIF":2.5,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11645906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of Pain ResearchPub Date : 2024-12-10eCollection Date: 2024-01-01DOI: 10.2147/JPR.S507165
Wensi Ouyang, Guimei Guo
{"title":"Clinical Outcomes of Exercise Rehabilitation for Degenerative Tibial Meniscal Tears: A Systematic Review and Meta-Analysis of Randomized Controlled Trials [Letter].","authors":"Wensi Ouyang, Guimei Guo","doi":"10.2147/JPR.S507165","DOIUrl":"10.2147/JPR.S507165","url":null,"abstract":"","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4159-4161"},"PeriodicalIF":2.5,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11645902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of Pain ResearchPub Date : 2024-12-07eCollection Date: 2024-01-01DOI: 10.2147/JPR.S495666
Zunyi Liu, Jiang Zhu
{"title":"Advances in Epidural Labor Analgesia for Obese Parturients.","authors":"Zunyi Liu, Jiang Zhu","doi":"10.2147/JPR.S495666","DOIUrl":"10.2147/JPR.S495666","url":null,"abstract":"<p><p>With the development of society and economy, and the improvement of people's living standards, obesity has gradually become a significant issue not only in China but globally. Epidural anesthesia, being the most commonly used method for labor analgesia in clinical practice, has significantly reduced the pain experienced by parturients during childbirth and decreased the cesarean delivery rate. However, due to the anatomical and physiological differences between obese and non-obese parturients, the effectiveness and techniques of labor analgesia may vary. This review focuses on the anatomical characteristics and drug differences in obese parturients, the methods of epidural labor analgesia in this population, the application of ultrasound in epidural puncture for obese parturients, and the complications associated with labor analgesia. The goal is to provide a guidance for clinical practice.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4141-4147"},"PeriodicalIF":2.5,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11633305/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of Pain ResearchPub Date : 2024-12-06eCollection Date: 2024-01-01DOI: 10.2147/JPR.S491060
Guillermo Ceniza-Bordallo, Eric Zimmermann, Marie Vigouroux, Kacper Niburski, Maryse Fortin, Jean Ouellet, Juan Pablo Cata, Pablo M Ingelmo
{"title":"Low Back Pain During and After Spaceflight: A Systematic Review with Meta-Analysis.","authors":"Guillermo Ceniza-Bordallo, Eric Zimmermann, Marie Vigouroux, Kacper Niburski, Maryse Fortin, Jean Ouellet, Juan Pablo Cata, Pablo M Ingelmo","doi":"10.2147/JPR.S491060","DOIUrl":"10.2147/JPR.S491060","url":null,"abstract":"<p><p>Space flights can produce physiological changes in the spine, leading to the development of acute and chronic pain in passengers. However, there is a lack of comprehensive literature exploring physiological spine changes and acute and chronic pain in space passengers (astronauts and animals). The first aim of this study was to identify the physiological changes experienced by passengers (humans and animals) after space flight. The second aim was to identify the incidence of low back pain during and after space flight. This systematic review was conducted following PRISMA guidelines and was pre-registered in PROSPERO (ID 451144). We included Randomized Controlled Trials or longitudinal studies in humans and animals, and the variables must be assessed either in-flight or post-flight. We conducted a literature search in major databases combining the keywords: Pain; Space; Low Back Pain; Astronauts; Spine Changes; Microgravity; Physiological Changes; Humans; Animals. Risk of bias and quality of studies were analyzed, and the level of evidence was assessed using the GRADE system. After duplicates were removed, 115 abstracts were screened by two reviewers, and finally, 11 articles were included in this review. The evidence indicates that astronauts experience muscle atrophy in the lumbar multifidus with a moderate to large effect, especially in the L4-L5 and L5-S1 segments. Space flights also decrease the range of motion with a moderate effect, along with disc herniations and disc dehydration. 77% of astronauts experience pain during spaceflight, and 47% develop acute pain after spaceflight. Chronic pain was reported by 33% of the astronauts. After space flights, astronauts suffer from lumbar muscle atrophy, reduced range of motion, disc herniations, and disc dehydration, with a high incidence of both acute and chronic pain.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4103-4139"},"PeriodicalIF":2.5,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11630706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of Pain ResearchPub Date : 2024-12-04eCollection Date: 2024-01-01DOI: 10.2147/JPR.S506274
Guo-Han Zhu, Jing-Hui Hu, Ke Peng
{"title":"Comment on \"Intravenous Lidocaine Compared with Quadratus Lumborum Block on Postoperative Analgesia Following Laparoscopic Renal Surgery: Protocol for a Randomized Noninferiority Trial\" [Response to Letter].","authors":"Guo-Han Zhu, Jing-Hui Hu, Ke Peng","doi":"10.2147/JPR.S506274","DOIUrl":"10.2147/JPR.S506274","url":null,"abstract":"","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4087-4088"},"PeriodicalIF":2.5,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11625431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of Pain ResearchPub Date : 2024-12-04eCollection Date: 2024-01-01DOI: 10.2147/JPR.S498373
Shannah Erasmus, Zhengyi Lyu, Jie Zhou, Jianqiao Fang, Yi Liang
{"title":"Electroacupuncture Mechanisms in Managing Preoperative Anxiety and Postoperative Pain Chronification: A Review.","authors":"Shannah Erasmus, Zhengyi Lyu, Jie Zhou, Jianqiao Fang, Yi Liang","doi":"10.2147/JPR.S498373","DOIUrl":"10.2147/JPR.S498373","url":null,"abstract":"<p><strong>Introduction: </strong>Postoperative hyperalgesic priming, exacerbated by preoperative anxiety, complicates pain management and recovery. Electroacupuncture (EA), a technique that combines traditional acupuncture with electrical stimulation applied through needles to enhance therapeutic effect, offers a potential solution by targeting multiple neurobiological pathways.</p><p><strong>Objective: </strong>This review investigates how EA addresses preoperative anxiety-induced postoperative hyperalgesic priming ie pain chronification, focusing on its mechanisms in three areas: preoperative anxiety, postoperative hyperalgesic priming, and the interaction between EA and these processes.</p><p><strong>Methods: </strong>A literature search across PubMed, ScienceDirect, and Google Scholar identified relevant studies on EA's effects on neurobiological pathways related to anxiety and pain. The review synthesized findings to understand EA's role in these contexts.</p><p><strong>Results: </strong>EA alleviates preoperative anxiety by influencing the body's neurochemical and neurophysiological responses. It reduces inflammation, regulates stress hormones, and improves autonomic function. For postoperative pain chronification, EA modulates pain pathways, reduces inflammation, and affects receptor signaling, gene expression, and neurotransmitter systems.</p><p><strong>Conclusion: </strong>EA offers a promising approach to managing preoperative anxiety and postoperative pain. By addressing both the physiological and neurochemical pathways that contribute to pain and anxiety, EA has the potential to significantly improve clinical outcomes for patients undergoing surgery. Further research is needed to fully understand its mechanisms and optimize its application in clinical settings.</p>","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4089-4100"},"PeriodicalIF":2.5,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11625428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of Pain ResearchPub Date : 2024-12-04eCollection Date: 2024-01-01DOI: 10.2147/JPR.S508145
Shibei Lv, Rubao Guo
{"title":"Comment on 'Musculoskeletal Ultrasound Assessment of the Clinical Efficacy of the Combination of Acupressure and \"Three Methods of Neck Movement (TCM)\" Therapy in the Treatment of Cervical Spondylosis: A Study Protocol for a Randomized Controlled Trial' [Letter].","authors":"Shibei Lv, Rubao Guo","doi":"10.2147/JPR.S508145","DOIUrl":"10.2147/JPR.S508145","url":null,"abstract":"","PeriodicalId":16661,"journal":{"name":"Journal of Pain Research","volume":"17 ","pages":"4101-4102"},"PeriodicalIF":2.5,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11625435/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}