Journal of Oral Microbiology最新文献_第6页

Shotgun metagenomic analysis of the oral microbiome in gingivitis: a nested case-control study 牙龈炎患者口腔微生物组的射枪元基因组分析：巢式病例对照研究

IF 4.5 2区医学

Journal of Oral Microbiology Pub Date : 2024-03-22 DOI: 10.1080/20002297.2024.2330867

Muhammed Manzoor, Jaakko Leskelä, Milla Pietiäinen, Nicolas Martinez-Majander, Eija Könönen, Teemu Niiranen, Leo Lahti, Juha Sinisalo, Jukka Putaala, Pirkko J. Pussinen, Susanna Paju

引用次数: 0

Oral and gut microbial profiling in periodontitis and Parkinson’s disease 牙周炎和帕金森病的口腔和肠道微生物图谱分析

IF 4.5 2区医学

Journal of Oral Microbiology Pub Date : 2024-03-21 DOI: 10.1080/20002297.2024.2331264

Ekin Yay, Melis Yilmaz, Hilal Toygar, Nur Balci, Carla Alvarez Rivas, Basak Bolluk Kılıç, Ali Zirh, Bruce J. Paster, Alpdogan Kantarci

引用次数: 0

Mediterranean diet: a potential player in the link between oral microbiome and oral diseases 地中海饮食：口腔微生物群与口腔疾病之间关系的潜在参与者

IF 4.5 2区医学

Journal of Oral Microbiology Pub Date : 2024-03-19 DOI: 10.1080/20002297.2024.2329474

Giuseppina Augimeri, Giovanna Caparello, Ippolito Caputo, Rodolfo Reda, Luca Testarelli, Daniela Bonofiglio

引用次数: 0

Genetic characterization of glyoxalase pathway in oral streptococci and its contribution to interbacterial competition 口腔链球菌乙醛化酶途径的遗传特征及其对细菌间竞争的贡献

IF 4.5 2区医学

Journal of Oral Microbiology Pub Date : 2024-03-03 DOI: 10.1080/20002297.2024.2322241

Lin Zeng, Payam Noeparvar, Robert A. Burne, Benjamin S. Glezer

引用次数: 0

The effects of nitrate on the oral microbiome: a systematic review investigating prebiotic potential 硝酸盐对口腔微生物群的影响：研究益生菌潜力的系统综述

IF 4.5 2区医学

Journal of Oral Microbiology Pub Date : 2024-02-27 DOI: 10.1080/20002297.2024.2322228

Siobhan P. Moran, Bob T. Rosier, Fiona L. Henriquez, Mia C. Burleigh

引用次数: 0

Characterization of pathogenic microbiome on removable prostheses with different levels of cleanliness using 2bRAD-M metagenomic sequencing. 使用 2bRAD-M 元基因组测序法分析不同清洁度的可摘义齿上的病原微生物群。

IF 4.5 2区医学

Journal of Oral Microbiology Pub Date : 2024-02-22 eCollection Date: 2024-01-01 DOI: 10.1080/20002297.2024.2317059

Tong Wah Lim, Shi Huang, Yuesong Jiang, Yufeng Zhang, Michael Francis Burrow, Colman McGrath

{"title":"Characterization of pathogenic microbiome on removable prostheses with different levels of cleanliness using 2bRAD-M metagenomic sequencing.","authors":"Tong Wah Lim, Shi Huang, Yuesong Jiang, Yufeng Zhang, Michael Francis Burrow, Colman McGrath","doi":"10.1080/20002297.2024.2317059","DOIUrl":"10.1080/20002297.2024.2317059","url":null,"abstract":"Background: The microbiomes on the surface of unclean removable prostheses are complex and yet largely underexplored using metagenomic sequencing technology.Objectives: To characterize the microbiome of removable prostheses with different levels of cleanliness using Type IIB Restriction-site Associated DNA for Microbiome (2bRAD-M) sequencing and compare the Microbial Index of Pathogenic Bacteria (MIP) between clean and unclean prostheses.Materials and methods: Ninety-seven removable prostheses were classified into 'clean' and 'unclean' groups. All prosthesis plaque samples underwent 2bRAD metagenomic sequencing to characterize the species-resolved microbial composition. MIPs for clean and unclean prostheses were calculated based on the sum of the relative abundance of pathogenic bacteria in a microbiome using a reference database that contains opportunistic pathogenic bacteria and disease-associated information.Results: Beta diversity analyses based on Jaccard qualitative and Bray-Curtis quantitative distance matrices identified significant differences between the two groups (p < 0.05). There was a significant enrichment of many pathogenic bacteria in the unclean prosthesis group. The MIP for unclean prostheses (0.47 ± 0.25) was significantly higher than for clean prostheses (0.37 ± 0.29), p = 0.029.Conclusions: The microbial community of plaque samples from 'unclean' prostheses demonstrated compositional differences compared with 'clean' prostheses. In addition, the pathogenic microbiome in the 'unclean' versus 'clean' group differed.","PeriodicalId":16598,"journal":{"name":"Journal of Oral Microbiology","volume":"16 1","pages":"2317059"},"PeriodicalIF":4.5,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10896157/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139972248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ecological competition in the oral mycobiome of Hispanic adults living in Puerto Rico associates with periodontitis 波多黎各西班牙裔成年人口腔真菌生物群的生态竞争与牙周炎的关系

IF 4.5 2区医学

Journal of Oral Microbiology Pub Date : 2024-02-21 DOI: 10.1080/20002297.2024.2316485

Kimil Acosta-Pagán, Benjamín Bolaños-Rosero, Cynthia Pérez, Ana P. Ortíz, Filipa Godoy-Vitorino

引用次数: 0

Secretome analysis and virulence assessment in Abiotrophia defectiva. Abiotrophia defectiva 的分泌组分析和毒力评估。

IF 4.5 2区医学

Journal of Oral Microbiology Pub Date : 2024-02-12 eCollection Date: 2024-01-01 DOI: 10.1080/20002297.2024.2307067

Radhika G Bhardwaj, Mai E Khalaf, Maribasappa Karched

{"title":"Secretome analysis and virulence assessment in Abiotrophia defectiva.","authors":"Radhika G Bhardwaj, Mai E Khalaf, Maribasappa Karched","doi":"10.1080/20002297.2024.2307067","DOIUrl":"10.1080/20002297.2024.2307067","url":null,"abstract":"Background: Abiotrophia defectiva, although infrequently occurring, is a notable cause of culture-negative infective endocarditis with limited research on its virulence. Associated with oral infections such as dental caries, exploring its secretome may provide insights into virulence mechanisms. Our study aimed to analyze and characterize the secretome of A. defectiva strain CCUG 27639.Methods: Secretome of A. defectiva was prepared from broth cultures and subjected to mass spectrometry and proteomics for protein identification. Inflammatory potential of the secretome was assessed by ELISA.Results: Eighty-four proteins were identified, with diverse subcellular localizations predicted by PSORTb. Notably, 20 were cytoplasmic, 12 cytoplasmic membrane, 5 extracellular, and 9 cell wall-anchored proteins. Bioinformatics tools revealed 54 proteins secreted via the 'Sec' pathway and 8 via a non-classical pathway. Moonlighting functions were found in 23 proteins, with over 20 exhibiting potential virulence properties, including peroxiredoxin and oligopeptide ABC transporter substrate-binding protein. Gene Ontology and KEGG analyses categorized protein sequences in various pathways. STRING analysis revealed functional protein association networks. Cytokine profiling demonstrated significant proinflammatory cytokine release (IL-8, IL-1β, and CCL5) from human PBMCs.Conclusions: Our study provides a comprehensive understanding of A. defectiva's secretome, laying the foundation for insights into its pathogenicity.","PeriodicalId":16598,"journal":{"name":"Journal of Oral Microbiology","volume":"16 1","pages":"2307067"},"PeriodicalIF":4.5,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10863525/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139729854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Manipulating the diseased oral microbiome: the power of probiotics and prebiotics. 操纵患病的口腔微生物群：益生菌和益生元的力量。

IF 3.7 2区医学

Journal of Oral Microbiology Pub Date : 2024-01-31 eCollection Date: 2024-01-01 DOI: 10.1080/20002297.2024.2307416

X Yu, D A Devine, J J Vernon

{"title":"Manipulating the diseased oral microbiome: the power of probiotics and prebiotics.","authors":"X Yu, D A Devine, J J Vernon","doi":"10.1080/20002297.2024.2307416","DOIUrl":"10.1080/20002297.2024.2307416","url":null,"abstract":"Dental caries and periodontal disease are amongst the most prevalent global disorders. Their aetiology is rooted in microbial activity within the oral cavity, through the generation of detrimental metabolites and the instigation of potentially adverse host immune responses. Due to the increasing threat of antimicrobial resistance, alternative approaches to readdress the balance are necessary. Advances in sequencing technologies have established relationships between disease and oral dysbiosis, and commercial enterprises seek to identify probiotic and prebiotic formulations to tackle preventable oral disorders through colonisation with, or promotion of, beneficial microbes. It is the metabolic characteristics and immunomodulatory capabilities of resident species which underlie health status. Research emphasis on the metabolic environment of the oral cavity has elucidated relationships between commensal and pathogenic organisms, for example, the sequential metabolism of fermentable carbohydrates deemed central to acid production in cariogenicity. Therefore, a focus on the preservation of an ecological homeostasis in the oral environment may be the most appropriate approach to health conservation. In this review we discuss an ecological approach to the maintenance of a healthy oral environment and debate the potential use of probiotic and prebiotic supplementation, specifically targeted at sustaining oral niches to preserve the delicately balanced microbiome.","PeriodicalId":16598,"journal":{"name":"Journal of Oral Microbiology","volume":"16 1","pages":"2307416"},"PeriodicalIF":3.7,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10833113/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139672029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antimicrobial effect of probiotic bacteriocins on Streptococcus mutans biofilm in a dynamic oral flow chamber model - an in vitro study. 益生菌细菌素在动态口腔流室模型中对变异链球菌生物膜的抗菌作用--一项体外研究。

IF 3.7 2区医学

Journal of Oral Microbiology Pub Date : 2024-01-28 eCollection Date: 2024-01-01 DOI: 10.1080/20002297.2024.2304971

Elisabeth Reichardt, Viktoriya Shyp, Lea Alig, Carlalberta Verna, Eva M Kulik, Michael M Bornstein

{"title":"Antimicrobial effect of probiotic bacteriocins on Streptococcus mutans biofilm in a dynamic oral flow chamber model - an in vitro study.","authors":"Elisabeth Reichardt, Viktoriya Shyp, Lea Alig, Carlalberta Verna, Eva M Kulik, Michael M Bornstein","doi":"10.1080/20002297.2024.2304971","DOIUrl":"10.1080/20002297.2024.2304971","url":null,"abstract":"Aim: To determine the antimicrobial activity of the bacteriocin-producing probiotic strains Streptococcus salivarius K12 and Streptococcus salivarius M18 alone or in combination against caries-associated Streptococcus mutans.Methods: Antimicrobial activity of S. salivarius K12 and/or S. salivarius M18 against S. mutans ATCC 25175 growth and biofilm formation on hydroxyapatite (HA) discs was determined in a flow chamber model by recording the colony forming units (CFU/ml) after 48 h of co-cultivation. The biofilm was analyzed by scanning electron microscopy (SEM) and by confocal laser scanning microscopy (CLSM). Additionally, the simultaneous antagonism assay was used to assess the inhibitory effect of S. salivarius K12 and/or S. salivarius M18 against S. mutans ATCC 25175 and 21 clinical isolates of S. mutans.Results: Co-cultivation of S. mutans and S. salivarius K12 and/or S. salivarius M18 led to the inhibition of S. mutans viability, thereby, preventing its biofilm formation on HA discs. Furthermore, S. salivarius K12 and S. salivarius M18 exhibited antimicrobial activity against most clinical isolates of S. mutans.Conclusion: The in vitro flow chamber system used in this study allows the simulation of time-dependent administration of S. salivarius probiotic strains, either alone or in combination, to investigate the prevention of S. mutans biofilm formation in a standardized model.","PeriodicalId":16598,"journal":{"name":"Journal of Oral Microbiology","volume":"16 1","pages":"2304971"},"PeriodicalIF":3.7,"publicationDate":"2024-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10823884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139577341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0