Journal of Ophthalmic & Vision Research最新文献

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The Relationship Between Deviation Control and Accommodative Load in Patients with Intermittent Exotropia. 间歇性外斜视患者偏差控制与调节负荷的关系。
IF 1.5
Journal of Ophthalmic & Vision Research Pub Date : 2026-03-02 eCollection Date: 2026-01-01 DOI: 10.18502/jovr.v21.17126
Pegah Behjati, Payam Nabovati, Mohammad Etezad Razavi, Abdollah Farzaneh
{"title":"The Relationship Between Deviation Control and Accommodative Load in Patients with Intermittent Exotropia.","authors":"Pegah Behjati, Payam Nabovati, Mohammad Etezad Razavi, Abdollah Farzaneh","doi":"10.18502/jovr.v21.17126","DOIUrl":"https://doi.org/10.18502/jovr.v21.17126","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the relationship between deviation control and accommodative load in patients with intermittent exotropia (IXT).</p><p><strong>Methods: </strong>A total of 35 patients with IXT aged 5-21 years (average, 10.46 <math><mo>±</mo></math> 4.42 years) with a best-corrected visual acuity of 20/20 or better were included in this study. All examinations, including binocular and monocular refraction, deviation angle, near stereoacuity, and deviation control, were done in patients with the best optical correction.</p><p><strong>Results: </strong>Of the 35 patients, 16 (45.7%) were male and 19 (54.3%) were female. The results indicated a statistically significant difference in the average distance and near deviation angles between good, relatively good, and poor deviation control levels (<i>P</i> = 0.012). The results also showed that the likelihood of deterioration in deviation control increased significantly with deviation angle (<i>P</i> = 0.012). The accommodative load of the right and left eyes at distance and near fixation did not differ significantly across the three levels of deviation control. Based on the results of univariate logistic regression, no statistically significant relationship was observed between accommodative load (both the right and left eyes at distance and near) and deviation control level. However, there was a significant difference between the accommodative loads of the left and right eyes at near and distance (<i>P</i> <math><mo><</mo></math> 0.001).</p><p><strong>Conclusion: </strong>In patients with IXT, deviation control decreased with deviation angle, and accommodative load increased in near fixation compared to distance fixation, but differences were not significant across the three deviation control groups (good, relatively good, and poor).</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"21 ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12972586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147433728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early Diagnosis of Glaucoma By Optical Coherence Tomography: A Systematic Review and Network Meta-analysis. 光学相干断层扫描早期诊断青光眼:系统综述和网络荟萃分析。
IF 1.5
Journal of Ophthalmic & Vision Research Pub Date : 2026-03-02 eCollection Date: 2026-01-01 DOI: 10.18502/jovr.v21.18852
Azadeh Doozandeh, Mohammadmehdi Hatami, Zahra Khorrami, Ali Sadatmoosavi, Mohammad Farjami, Ghazale Soltani
{"title":"Early Diagnosis of Glaucoma By Optical Coherence Tomography: A Systematic Review and Network Meta-analysis.","authors":"Azadeh Doozandeh, Mohammadmehdi Hatami, Zahra Khorrami, Ali Sadatmoosavi, Mohammad Farjami, Ghazale Soltani","doi":"10.18502/jovr.v21.18852","DOIUrl":"https://doi.org/10.18502/jovr.v21.18852","url":null,"abstract":"<p><p>Optical coherence tomography (OCT) diagnostic technology is increasingly being integrated into clinical practice and is evolving rapidly. Performing a meta-analysis of these advancements can provide valuable insights to clinicians and healthcare decision-makers and help identify gaps that need further research and development. We conducted a systematic review and network meta-analysis (NMA) comparing the diagnostic accuracy of three key OCT-derived parameters in identifying early glaucoma: peripapillary retinal nerve fiber layer (RNFL) thickness, macular metrics, and optic nerve head (ONH) characteristics. We systematically searched PubMed, Embase, Web of Science, and Scopus for studies published from January 2004 through March 2024, and identified 47 eligible studies. These studies comprised 12,723 eyes from 8177 participants, including patients with mild primary open-angle glaucoma, pre-perimetric glaucoma (PPG), and ocular hypertension, as well as healthy controls. Our NMA summarized the existing evidence on the diagnostic performance of these parameters. The highest diagnostic accuracies for glaucoma detection were observed for average and inferior RNFL parameters, both achieving an accuracy of 0.77 and macular GLV parameter with an accuracy of 0.76. These were followed by inferotemporal GCIPL and two ONH parameters-rim area and cup-to-disc ratio-each with an accuracy of 0.75. In conclusion, the overall diagnostic accuracy was comparable across all three categories of OCT parameters. The results also suggest the potential benefits of combining two or three of these parameters in a single report, along with the application of artificial intelligence. This approach could significantly enhance the diagnostic accuracy of OCT in detecting glaucoma at its earliest stages, ultimately improving patient outcomes through earlier intervention.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"21 ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12972587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147433653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
One-year Success Rate of Selective Laser Trabeculoplasty in Pseudoexfoliative Glaucoma: A Prospective Study. 选择性激光小梁成形术治疗假剥脱性青光眼一年成功率的前瞻性研究。
IF 1.5
Journal of Ophthalmic & Vision Research Pub Date : 2026-02-19 eCollection Date: 2026-01-01 DOI: 10.18502/jovr.v21.17046
Behzad Fallahi Motlagh, Amin Arasteh, Ali Mostafaie, Hakimallah Ghalamara, Farhad Najafzadeh
{"title":"One-year Success Rate of Selective Laser Trabeculoplasty in Pseudoexfoliative Glaucoma: A Prospective Study.","authors":"Behzad Fallahi Motlagh, Amin Arasteh, Ali Mostafaie, Hakimallah Ghalamara, Farhad Najafzadeh","doi":"10.18502/jovr.v21.17046","DOIUrl":"https://doi.org/10.18502/jovr.v21.17046","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the 1-year effectiveness of selective laser trabeculoplasty (SLT) in patients with pseudoexfoliative glaucoma (PEXG).</p><p><strong>Methods: </strong>This prospective, single-arm, non-randomized interventional study involved 40 eyes from 40 patients with PEXG with no history of glaucoma surgery and laser trabeculoplasty. All participants underwent a single session of 360º SLT. Follow-up visits were conducted at 2 hours, 1 day, 1 week, and at 1, 2, 3, 4, 5, 6, and 12 months after the procedure. The intraocular pressure (IOP), the number of anti-glaucoma medications (NOM), and the 1-year success rate were investigated as primary outcome measures; while the incidence of adverse effects was considered the secondary outcome. Treatment success was defined as a <math><mo>≥</mo></math> 20% decrease in IOP compared to baseline.</p><p><strong>Results: </strong>The baseline IOP was 22.19 <math><mo>±</mo></math> 2.08 mmHg, and the mean NOM was 3.12 <math><mo>±</mo></math> 0.55 before the SLT procedure. The mean IOP was significantly lower at all follow-up visits than at baseline, whereas the mean NOM remained unchanged throughout the follow-up period. The mean IOP values at 1, 3, 6, and 12 months after SLT were 18.02, 16.92, 16.47, and 15.31 mmHg, respectively. The overall 1-year success rate was 85%, with an average IOP reduction of 31.0% relative to baseline. The most common adverse event following SLT was mild anterior chamber inflammation, which occurred in 32.5% of eyes.</p><p><strong>Conclusion: </strong>The SLT procedure could significantly reduce IOP in patients with PEXG with minimal adverse effects. The 1-year outcomes were favorable, suggesting that SLT may serve as an effective primary or complementary treatment for PEXG.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"21 ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12921533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147271217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corneal and Ocular Aberrations: A Comparative Study of Hyperopic, Emmetropic, and Myopic Eyes. 角膜和眼像差:远视、屈光不正和近视的比较研究。
IF 1.5
Journal of Ophthalmic & Vision Research Pub Date : 2026-02-16 eCollection Date: 2026-01-01 DOI: 10.18502/jovr.v21.18138
Amir Golmakani, Negareh Yazdani, Jamshid Jamali, Asieh Ehsaei
{"title":"Corneal and Ocular Aberrations: A Comparative Study of Hyperopic, Emmetropic, and Myopic Eyes.","authors":"Amir Golmakani, Negareh Yazdani, Jamshid Jamali, Asieh Ehsaei","doi":"10.18502/jovr.v21.18138","DOIUrl":"https://doi.org/10.18502/jovr.v21.18138","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate differences in corneal and ocular aberrations between hyperopic, emmetropic, and myopic eyes.</p><p><strong>Methods: </strong>This cross-sectional study included 84 eyes from 84 healthy participants (age range 18-35 years), who were equally divided into three refractive error groups of hyperopia, emmetropia, and myopia. Following comprehensive optometric examinations, corneal and ocular aberrations were measured using Pentacam and Zywave imaging systems, respectively. Aberrations were measured for a pupil diameter of 5 mm. Root-mean-square (RMS), Zernike coefficients, and compensation factor (CF) between total ocular and corneal aberrations were calculated for statistical analysis.</p><p><strong>Results: </strong>The mean spherical equivalent was +1.96 <math><mo>±</mo></math> 1.64, -0.17 <math><mo>±</mo></math> 0.19, and -2.46 <math><mo>±</mo></math> 1.56 diopters in hyperopic (H), emmetropic (E), and myopic (M) eyes, respectively. The amount of corneal Zernike coefficients Z<sub>4</sub> <sup>-2</sup> in the hyperopic eyes (H: 0.015 <math><mo>±</mo></math> 0.040) was significantly higher than that of emmetropic eyes (E: -0.018 <math><mo>±</mo></math> 0.054) and myopic eyes (M: -0.003 <math><mo>±</mo></math> 0.038) with a <i>P-</i>value of 0.029. The RMS of corneal total coma (H: 0.228 <math><mo>±</mo></math> 0.097, E: 0.183 <math><mo>±</mo></math> 0.086, M: 0.164 <math><mo>±</mo></math> 0.083, <i>P</i>-value: 0.009, respectively) and RMS of ocular fifth-order (H: 0.045 <math><mo>±</mo></math> 0.018, E: 0.036 <math><mo>±</mo></math> 0.020, M: 0.032 <math><mo>±</mo></math> 0.016, <i>P</i>-value: 0.002) showed a significant difference between refractive error groups, with higher value in hyperopic eyes compared to the two other groups. There was no significant difference in CF for RMS and Zernike coefficients among the refractive error groups.</p><p><strong>Conclusion: </strong>Hyperopic eyes showed a higher RMS value for ocular fifth-order and corneal coma aberrations compared to the emmetropic and myopic eyes.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"21 ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12921453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147271236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Silico Design and Analysis of a Novel Ranibizumab-derived Peptide against the Vascular Endothelial Growth Factor. 一种抗血管内皮生长因子的新型雷尼单抗衍生肽的计算机设计与分析。
IF 1.5
Journal of Ophthalmic & Vision Research Pub Date : 2026-02-16 eCollection Date: 2026-01-01 DOI: 10.18502/jovr.v21.16222
Mehrdad Afarid, Roghayyeh Baghban, Samaneh Ghasemali, Javad Zamani, Athar Zareei
{"title":"<i>In Silico</i> Design and Analysis of a Novel Ranibizumab-derived Peptide against the Vascular Endothelial Growth Factor.","authors":"Mehrdad Afarid, Roghayyeh Baghban, Samaneh Ghasemali, Javad Zamani, Athar Zareei","doi":"10.18502/jovr.v21.16222","DOIUrl":"https://doi.org/10.18502/jovr.v21.16222","url":null,"abstract":"<p><strong>Purpose: </strong>Blocking the interaction between vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor-2 (VEGFR2) is recognized as an effective strategy for treating neovascular age-related macular degeneration (nAMD). The present research aimed at designing and modelling an anti-VEGF peptide based on ranibizumab for potential application in inhibiting the VEGF/VEGFR2 interaction.</p><p><strong>Methods: </strong>Effective amino acids in the interaction between VEGF and ranibizumab were analyzed using Swiss-PdbViewer (SPDBV), PyMOL, and Chimera software. The effective area in this interaction was determined and applied as a basis to design a peptide. Then, this sequence (containing 25 amino acids) was subjected to random mutagenesis, and the binding affinity of the resulting peptides was analyzed using the ClusPro software. Subsequently, GROMACS v5.0.6 was employed for molecular dynamics (MD) simulations to evaluate the stability of target-ligand complexes. Ultimately, the peptide exhibiting the highest affinity was grafted into the kB1 and MCoTI-II frameworks to enhance the stability.</p><p><strong>Results: </strong>This modification resulted in improved peptide-VEGF binding affinity, demonstrating the potential of <i>in silico</i> design for creating effective anti-angiogenic peptides in antiangiogenic therapies.</p><p><strong>Conclusion: </strong>The findings from this study provide a basis for designing and validating peptide inhibitors against VEGF.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"21 ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12921458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147271219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phacoemulsification and Viscocanalostomy With or Without Silicone Implant in Primary Open-angle Glaucoma: A Randomized Clinical Trial. 有或没有硅胶植入治疗原发性开角型青光眼的超声乳化术和粘管吻合:一项随机临床试验。
IF 1.5
Journal of Ophthalmic & Vision Research Pub Date : 2026-02-16 eCollection Date: 2026-01-01 DOI: 10.18502/jovr.v21.17712
Saeed Shokouhi Rad, Ali Bagheri Asl, Shabnam Niroumand, Hamid Reza Heidarzadeh
{"title":"Phacoemulsification and Viscocanalostomy With or Without Silicone Implant in Primary Open-angle Glaucoma: A Randomized Clinical Trial.","authors":"Saeed Shokouhi Rad, Ali Bagheri Asl, Shabnam Niroumand, Hamid Reza Heidarzadeh","doi":"10.18502/jovr.v21.17712","DOIUrl":"https://doi.org/10.18502/jovr.v21.17712","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the outcomes of combined phacoemulsification and viscocanalostomy with versus without intrascleral implantation of Ahmed glaucoma valve (AGV) tube remnants in patients with primary open-angle glaucoma (POAG) and cataract.</p><p><strong>Methods: </strong>A randomized clinical trial involving 60 patients with cataract and POAG was carried out. The case group underwent phacoemulsification and viscocanalostomy together with intrascleral implantation of AGV tube remnants, while the control group underwent the same procedures without any implant. The two groups were compared in terms of best-corrected visual acuity (BCVA), intraocular pressure (IOP), cup-to-disc ratio, number of ocular hypotensive medications, surgical success rate, and scleral lake size.</p><p><strong>Results: </strong>Sixty patients were enrolled and equally divided into two groups. Postoperative IOP, BCVA, and cup-to-disc ratio did not differ significantly between the groups (<i>P</i> = 0.196, <i>P</i> = 0.724, and <i>P</i> = 0.443, respectively). Despite comparable IOP outcomes, the case group required a significantly higher number of ocular hypotensive medications at the final follow-up (<i>P</i> = 0.043). Anterior segment optical coherence tomography (AS-OCT) revealed significantly larger scleral lake dimensions in the case group in terms of length, height, surface area, and perimeter (all <i>P</i> <math><mo>≤</mo></math> 0.001).</p><p><strong>Conclusion: </strong>Our study found no significant difference in success rates or postoperative IOP control between combined phacoemulsification and viscocanalostomy with or without silicone implants. Although the case group demonstrated larger scleral lake dimensions on AS-OCT, this anatomical difference did not translate into superior IOP outcomes and was associated with a higher requirement for postoperative ocular hypotensive medications. The clinical significance of increased scleral lake size in the presence of an implant remains uncertain, and longer-term follow-up is warranted.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"21 ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12921452/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147271173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Authors' Reply to "Neuro-Ophthalmologic Complications of SARS-Cov-2 Infections and Vaccinations" [J Ophthalmic Vis Res 2024;19:140-141]. “SARS-Cov-2感染的神经并发症与疫苗接种”的报告[J]; contemporary medicine; 2009;19(1): 90 - 90。
IF 1.5
Journal of Ophthalmic & Vision Research Pub Date : 2026-02-04 eCollection Date: 2026-01-01 DOI: 10.18502/jovr.v21.13220
Mehdi Tavakoli, Danielle R Isen, Mohadeseh Feizi
{"title":"Authors' Reply to \"Neuro-Ophthalmologic Complications of SARS-Cov-2 Infections and Vaccinations\" [J Ophthalmic Vis Res 2024;19:140-141].","authors":"Mehdi Tavakoli, Danielle R Isen, Mohadeseh Feizi","doi":"10.18502/jovr.v21.13220","DOIUrl":"10.18502/jovr.v21.13220","url":null,"abstract":"<p><p>This letter responds to the letter titled \"Neuro-Ophthalmologic Complications of SARS-Cov-2 Infections and Vaccinations,\" published in J Ophthalmic Vis Res 2024;19:140-141 with DOI: https://doi.org/10.18502/jovr.v19i1.15451.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"21 ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12884100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146157444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of Spherophakia- or Microspherophakia-associated Mild to Moderate Glaucoma with Lensectomy, Anterior Vitrectomy, and Iris-Claw Intraocular Lens Implantation. 晶状体切除术、前玻璃体切除术和虹膜爪式人工晶状体植入术治疗球体或微球体相关的轻中度青光眼。
IF 1.5
Journal of Ophthalmic & Vision Research Pub Date : 2026-01-14 eCollection Date: 2026-01-01 DOI: 10.18502/jovr.v21.17682
Aidin Meshksar, Masoumeh Masoumpour, Mohammad Hossein Nowroozzadeh, Reza Razeghinejad
{"title":"Management of Spherophakia- or Microspherophakia-associated Mild to Moderate Glaucoma with Lensectomy, Anterior Vitrectomy, and Iris-Claw Intraocular Lens Implantation.","authors":"Aidin Meshksar, Masoumeh Masoumpour, Mohammad Hossein Nowroozzadeh, Reza Razeghinejad","doi":"10.18502/jovr.v21.17682","DOIUrl":"10.18502/jovr.v21.17682","url":null,"abstract":"<p><strong>Purpose: </strong>To report the outcomes of lensectomy, anterior vitrectomy, and iris-claw lens implantation in patients with spherophakia- or microspherophakia-related glaucoma.</p><p><strong>Methods: </strong>In this retrospective case series, we focused on patients with isolated microspherophakia or microspherophakia associated with various syndromes and mild to moderate angle-closure glaucoma who had undergone lensectomy, anterior vitrectomy, and iris-claw lens implantation.</p><p><strong>Results: </strong>We analyzed a total of 12 eyes of 6 patients with a mean age of 19 <math><mo>±</mo></math> 6 years and a mean postoperative follow-up of 66 <math><mo>±</mo></math> 12 months. All patients had lenticular myopia, and the mean refraction improved from <math><mo>-</mo></math> 7.26 <math><mo>±</mo></math> 0.67 diopters (D) to <math><mo>-</mo></math> 1.18 <math><mo>±</mo></math> 1.04 D after surgery. The mean corrected visual acuity improved from 0.92 <math><mo>±</mo></math> 0.57 logMAR before surgery to 0.17 <math><mo>±</mo></math> 0.15 logMAR at the last follow-up (<i>P</i> = 0.001). The mean intraocular pressure (IOP) decreased from 21.2 <math><mo>±</mo></math> 3.9 mmHg on 1.9 <math><mo>±</mo></math> 0.7 anti-glaucoma medications at baseline to 15.0 <math><mo>±</mo></math> 1.5 mmHg (<i>P</i> = 0.006) on 0.8 <math><mo>±</mo></math> 0.7 medications (<i>P</i> = 0.006) at the last follow-up.</p><p><strong>Conclusion: </strong>Lensectomy and iris-claw lens implantation in our cases not only decreased the IOP and reduced the number of glaucoma medications, but also improved the best-corrected visual acuity. Removal of the abnormally shaped lens likely contributed to these changes.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"21 ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12828235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146052537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urbanization Inequalities on the Incidence of Intraocular Cancers in Iran: An 11-Year Nationwide Retrospective Ecological Study. 城市化对伊朗眼内癌发病率的影响:一项为期11年的全国回顾性生态学研究。
IF 1.5
Journal of Ophthalmic & Vision Research Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.18502/jovr.v20.16500
Sare Safi, Zahra Khorrami, Mohadese Ahmadzade, Mohammad Esmaeil Akbari, Hamidreza Rouientan, Seyed Mohammadmehdi Moshtaghion, Mohammad Abolhosseini, Mozhgan Rezaei Kanavi, Saeed Karimi
{"title":"Urbanization Inequalities on the Incidence of Intraocular Cancers in Iran: An 11-Year Nationwide Retrospective Ecological Study.","authors":"Sare Safi, Zahra Khorrami, Mohadese Ahmadzade, Mohammad Esmaeil Akbari, Hamidreza Rouientan, Seyed Mohammadmehdi Moshtaghion, Mohammad Abolhosseini, Mozhgan Rezaei Kanavi, Saeed Karimi","doi":"10.18502/jovr.v20.16500","DOIUrl":"10.18502/jovr.v20.16500","url":null,"abstract":"<p><strong>Purpose: </strong>To report the relationship between urbanization and the incidence of intraocular cancers in Iran.</p><p><strong>Methods: </strong>In this retrospective ecological study, data were extracted from the Statistical Center of Iran, the Meteorological Organization, and the Iranian National Population-based Cancer Registry (INPCR, 2006-2016). The urbanization index (UI) was calculated using principal component analysis, and weighted multiple linear regression was used to assess the relationship between the UI and the age-standardized incidence rate (ASIR) of intraocular cancers.</p><p><strong>Results: </strong>Six hundred and fifty-four intraocular cancer cases with a gender ratio (male-to-female) of 1:13 were recorded. The mean total 11-year ASIR of intraocular cancers was 0.093 per 100,000 population. The mean ASIR showed a decrease of 0.051 per 100,000 from 2006 to 2016 (<i>P</i> = 0.022). Retinoblastoma (66.1%) and uveal melanoma (24.6%) were the most commonly diagnosed intraocular cancers, and their ASIR declined between 2006 and 2016. Once adjusted for environmental pollutants, an increase in the area-based UI was significantly associated with lower total ASIR of intraocular cancers in males ( <math><mi>β</mi></math> = -0.14).</p><p><strong>Conclusion: </strong>Urbanization was associated with a reduction in ASIR of intraocular cancers, which can be attributed to improved access to eye care facilities for timely diagnosis. However, given that the INPCR cases were verified only by histology, future research should be conducted on hospital-based registries using multiple data sources to address confounders and exposure factors and prevent underestimation of incidence rates.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"20 ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12826603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146052539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retinal and Choroidal Metastasis from a Lung Carcinoid Tumor. 一类肺癌的视网膜和脉络膜转移。
IF 1.5
Journal of Ophthalmic & Vision Research Pub Date : 2025-12-19 eCollection Date: 2025-01-01 DOI: 10.18502/jovr.v20.17830
Corrina P Azarcon, Caroline M Craven, Jill R Wells
{"title":"Retinal and Choroidal Metastasis from a Lung Carcinoid Tumor.","authors":"Corrina P Azarcon, Caroline M Craven, Jill R Wells","doi":"10.18502/jovr.v20.17830","DOIUrl":"10.18502/jovr.v20.17830","url":null,"abstract":"","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"20 ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12728302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145833928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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