Journal of Ophthalmic & Vision Research最新文献

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P100 Wave Latency and Amplitude in Visual Evoked Potential Records in Different Visual Quadrants of Normal Individuals. 正常人不同视觉象限视觉诱发电位记录的P100波潜伏期和振幅。
IF 2
Journal of Ophthalmic & Vision Research Pub Date : 2023-04-01 DOI: 10.18502/jovr.v18i2.13184
Leila Mirzaee Saba, Hassan Hashemi, Ebrahim Jafarzadehpour, Ali Mirzajani, Abbasali Yekta, Abolfazl Jafarzadehpour, Arghavan Zarei, Payam Nabovati, Mehdi Khabazkhoob
{"title":"P100 Wave Latency and Amplitude in Visual Evoked Potential Records in Different Visual Quadrants of Normal Individuals.","authors":"Leila Mirzaee Saba,&nbsp;Hassan Hashemi,&nbsp;Ebrahim Jafarzadehpour,&nbsp;Ali Mirzajani,&nbsp;Abbasali Yekta,&nbsp;Abolfazl Jafarzadehpour,&nbsp;Arghavan Zarei,&nbsp;Payam Nabovati,&nbsp;Mehdi Khabazkhoob","doi":"10.18502/jovr.v18i2.13184","DOIUrl":"https://doi.org/10.18502/jovr.v18i2.13184","url":null,"abstract":"<p><strong>Purpose: </strong>Assessment of the pattern visual evoked potential (PVEP) responses in different areas of visual fields in individuals with normal vision.</p><p><strong>Methods: </strong>This study was conducted on 80 eyes of normal subjects aged 18-35 years. All participants underwent refraction and visual acuity examination. Visual evoked potential (VEP) responses were recorded in different areas of field. The repeated measure test was used to compare the P100 latency and amplitude of PVEP among different areas.</p><p><strong>Results: </strong>The repeated measures analysis of variance showed a statistically significant difference among different areas in terms of amplitude and latency of P100 (<i>P</i> = 0.002 and <i>P</i> <math><mo><</mo></math> 0.001, respectively). According to the results, the highest and lowest amplitude of P100 was observed in inferior-nasal and superior areas, respectively. The highest and lowest latency of P100 was related to the temporal and inferior-nasal areas, respectively.</p><p><strong>Conclusion: </strong>This study partially revealed the details of local PVEP distribution in the visual field and there was a significant difference in the amplitude and latency of PVEP wave in different areas of the visual field.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"175-181"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172794/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9523700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Renal Function following Fluorescein Angiography in Diabetic Patients with Chronic Kidney Disease. 糖尿病合并慢性肾病患者荧光素血管造影后的肾功能。
IF 2
Journal of Ophthalmic & Vision Research Pub Date : 2023-04-01 DOI: 10.18502/jovr.v18i2.13183
Nazanin Ebrahimiadib, Shaghayegh Hadavand Mirzaei, Hamid Riazi-Esfahani, Manouchehr Amini
{"title":"Renal Function following Fluorescein Angiography in Diabetic Patients with Chronic Kidney Disease.","authors":"Nazanin Ebrahimiadib,&nbsp;Shaghayegh Hadavand Mirzaei,&nbsp;Hamid Riazi-Esfahani,&nbsp;Manouchehr Amini","doi":"10.18502/jovr.v18i2.13183","DOIUrl":"https://doi.org/10.18502/jovr.v18i2.13183","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effect of fluorescein dye usage on renal function in patients with diabetic retinopathy (DR) and chronic kidney disease (CKD).</p><p><strong>Methods: </strong>Diabetic patients with retinopathy who were candidate for fundus fluorescein angiography (FA) were evaluated for serum creatinine and urea levels within five days prior to performing the FA. Serum creatinine levels of 1.5 mg/dl or more in males and 1.4 mg/dl or more in females were both identified as CKD and were included in the study. An increase of 0.5 mg/dl or 25% in creatinine after FA was considered as contrast-induced acute kidney injury (AKI). Estimated glomerular filtration rate (eGFR) was also calculated for all patients using a CKD-Epi formula. CKD grading was determined based on eGFR values.</p><p><strong>Results: </strong>Forty-two patients agreed to participate, of which 23 (54.8%) were male. Seventeen patients were identified with grade 3a or lower CKD, 12 with grade 3b, 11 with grade 4, and two with grade 5 CKD. Considering all grades of CKD, the mean blood urea before and after angiography was 58.48 <math><mo>±</mo></math> 26.7 and 57 <math><mo>±</mo></math> 27.81 mg/dl, respectively (<i>P</i> = 0.475). The mean serum creatinine before and after the test was 1.89 <math><mo>±</mo></math> 1.04 and 1.87<math><mo>±</mo></math>0.99 mg/dl, respectively (<i>P</i> = 0.993). The mean eGFR before and after the test was 44.024 <math><mo>±</mo></math> 23.5447 and 43.850 <math><mo>±</mo></math> 21.8581 mL/min/1.73 m<sup>2</sup> <i>(P = 0.</i>875).</p><p><strong>Conclusion: </strong>According to the findings of this study, FA does not seem to further deteriorate kidney function in patients with diabetic associated CKD.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"170-174"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9523701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Ziv-aflibercept in Diabetic Macular Edema: Relation of Subfoveal Choroidal Thickness with Visual and Anatomical Outcomes. ziva - afliberept治疗糖尿病黄斑水肿:中央凹下脉络膜厚度与视觉和解剖结果的关系。
IF 2
Journal of Ophthalmic & Vision Research Pub Date : 2023-04-01 DOI: 10.18502/jovr.v18i2.13182
Siamak Moradian, Masoud Soheilian, Mahsan Asadi, Abdolreza Baghi, Hamid Safi, Seyed-Hossein Abtahi
{"title":"Ziv-aflibercept in Diabetic Macular Edema: Relation of Subfoveal Choroidal Thickness with Visual and Anatomical Outcomes.","authors":"Siamak Moradian,&nbsp;Masoud Soheilian,&nbsp;Mahsan Asadi,&nbsp;Abdolreza Baghi,&nbsp;Hamid Safi,&nbsp;Seyed-Hossein Abtahi","doi":"10.18502/jovr.v18i2.13182","DOIUrl":"https://doi.org/10.18502/jovr.v18i2.13182","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effects of intravitreal ziv-aflibercept injections (IVZ) on subfoveal choroidal thickness (SCT) as well as on central macular thickness (CMT) and on best corrected visual acuity (BCVA) changes in eyes with center-involved diabetic macular edema (CI-DME).</p><p><strong>Methods: </strong>Fifty-seven eyes of 36 patients with CI-DME were included in this prospective interventional case series. Structural optical coherence tomography (OCT) and enhanced depth imaging OCT were performed at baseline followed by three monthly 1.25 mg IVZ injections. Changes of SCT, CMT, and BCVA at each follow-up session were assessed. The association between baseline SCT and its monthly changes with final visual and anatomical outcomes were also assessed.</p><p><strong>Results: </strong>CMT at baseline, and at the first, second, and third month follow-up sessions were 396 <math><mo>±</mo></math> 119, 344 <math><mo>±</mo></math> 115, 305 <math><mo>±</mo></math> 89, and 296 <math><mo>±</mo></math> 101 μm, respectively (<i>P</i>-value <math><mo><</mo></math> 0.001). SCT at baseline, and at months one, two, and three were 236 <math><mo>±</mo></math> 47, 245 <math><mo>±</mo></math> 56, 254 <math><mo>±</mo></math> 54, and 241 <math><mo>±</mo></math> 54 μm, respectively (<i>P</i>-value <math><mo>></mo></math> 0.99). Corresponding figures for BCVA were 0.58 <math><mo>±</mo></math> 0.29, 0.47 <math><mo>±</mo></math> 0.31, 0.4 <math><mo>±</mo></math> 0.24, and 0.37 <math><mo>±</mo></math> 0.23 LogMAR, respectively (<i>P</i>-value <math><mo><</mo></math> 0.001). There was a statistically significant positive correlation between BCVA and CMT changes following IVZ injections (<i>P</i>-value <math><mo><</mo></math> 0.001). However, there were no significant correlations between SCT changes and visual acuity (VA) and CMT changes following IVZ injections.</p><p><strong>Conclusion: </strong>IVZ improved visual outcomes and macular thickness profiles in patients with CI-DME. However, IVZ had no significant effect on SCT. Baseline SCT and its monthly changes had no association with visual and anatomical outcomes.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"164-169"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9822862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Congenital Retinal Macrovessel; Optical Coherence Tomography Angiography Features. 先天性视网膜大血管;光学相干断层血管造影特征。
IF 2
Journal of Ophthalmic & Vision Research Pub Date : 2023-04-01 DOI: 10.18502/jovr.v18i2.13191
Ramin Nourinia, Kiana Hassanpour
{"title":"Congenital Retinal Macrovessel; Optical Coherence Tomography Angiography Features.","authors":"Ramin Nourinia,&nbsp;Kiana Hassanpour","doi":"10.18502/jovr.v18i2.13191","DOIUrl":"https://doi.org/10.18502/jovr.v18i2.13191","url":null,"abstract":"This is a Photo Essay and does not have an abstract. Please download the PDF or view the article in HTML.","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"245-248"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172802/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9822858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Survey on Orbital Space-Occupying Lesions during a Twelve-Year Period from a Referral Center in Iran. 伊朗一家转诊中心12年间眼眶占位性病变的调查。
IF 2
Journal of Ophthalmic & Vision Research Pub Date : 2023-04-01 DOI: 10.18502/jovr.v18i2.13187
Abbas Bagheri, Parisa Ashtar-Nakhaie, Maryam Aletaha, Bahareh Kheiri, Amirreza Veisi
{"title":"A Survey on Orbital Space-Occupying Lesions during a Twelve-Year Period from a Referral Center in Iran.","authors":"Abbas Bagheri,&nbsp;Parisa Ashtar-Nakhaie,&nbsp;Maryam Aletaha,&nbsp;Bahareh Kheiri,&nbsp;Amirreza Veisi","doi":"10.18502/jovr.v18i2.13187","DOIUrl":"https://doi.org/10.18502/jovr.v18i2.13187","url":null,"abstract":"<p><strong>Purpose: </strong>In this study, we describe different orbital space-occupying lesions (SOLs) from a referral center in Iran.</p><p><strong>Methods: </strong>In this retrospective case series, all records of \"orbital tumors\" with a definite histopathologic diagnosis at a referral center in Iran were reviewed from April 2008 to May 2020.</p><p><strong>Results: </strong>A total of 375 orbital SOLs were included. The study population consisted of 212 (56.5%) female and 163 (43.5%) male subjects with overall mean age of 31.09 <math><mo>±</mo></math> 21.80 years. The most common clinical presentation was proptosis and the superotemporal quadrant was the most frequent site of involvement. Extraconal lesions (276 cases, 73.6%) outnumbered intraconal lesions (99 cases 26.4%). The great majority of SOLs (344, 91.7%) were primary, while 24 (6.4%) were secondary and 7 (1.9%) were metastatic. Benign lesions (309, 82.4%) were much more common than malignant SOLs (66, 17.6%). Overall, dermoid cysts and malignant lymphoma were the most prevalent benign and malignant orbital SOLs, respectively. The malignant to benign lesion ratio was 0.46 in children (<math><mo>≤</mo></math>18 years), 0.81 in middle-aged subjects (19-59 years), and 5.9 in older (<math><mo>≥</mo></math>60 years) cases. The most common type of malignancy was rhabdomyosarcoma in children, lymphoma in middle-aged subjects, and invasive basal cell carcinoma in older age group.</p><p><strong>Conclusion: </strong>Over the 12-year study period, benign, primary, extraconal orbital SOLs were more frequent than malignant, secondary, and intraconal lesions. The ratio of malignant lesions increased with age in this cohort of patients.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"202-211"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9523702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Clinical Applications of Artificial Intelligence in Glaucoma. 人工智能在青光眼中的临床应用。
IF 2
Journal of Ophthalmic & Vision Research Pub Date : 2023-02-21 eCollection Date: 2023-01-01 DOI: 10.18502/jovr.v18i1.12730
Siamak Yousefi
{"title":"Clinical Applications of Artificial Intelligence in Glaucoma.","authors":"Siamak Yousefi","doi":"10.18502/jovr.v18i1.12730","DOIUrl":"10.18502/jovr.v18i1.12730","url":null,"abstract":"<p><p>Ophthalmology is one of the major imaging-intensive fields of medicine and thus has potential for extensive applications of artificial intelligence (AI) to advance diagnosis, drug efficacy, and other treatment-related aspects of ocular disease. AI has made impressive progress in ophthalmology within the past few years and two autonomous AI-enabled systems have received US regulatory approvals for autonomously screening for mid-level or advanced diabetic retinopathy and macular edema. While no autonomous AI-enabled system for glaucoma screening has yet received US regulatory approval, numerous assistive AI-enabled software tools are already employed in commercialized instruments for quantifying retinal images and visual fields to augment glaucoma research and clinical practice. In this literature review (non-systematic), we provide an overview of AI applications in glaucoma, and highlight some limitations and considerations for AI integration and adoption into clinical practice.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 1","pages":"97-112"},"PeriodicalIF":2.0,"publicationDate":"2023-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020779/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9146895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuro-ophthalmic Manifestations of Coronavirus Disease 2019 and Its Vaccination: A Narrative Review. 2019年冠状病毒病的神经眼科表现及其疫苗接种:叙述性综述。
IF 1.6
Journal of Ophthalmic & Vision Research Pub Date : 2023-02-21 eCollection Date: 2023-01-01 DOI: 10.18502/jovr.v18i1.12731
Mohadeseh Feizi, Danielle R Isen, Mehdi Tavakoli
{"title":"Neuro-ophthalmic Manifestations of Coronavirus Disease 2019 and Its Vaccination: A Narrative Review.","authors":"Mohadeseh Feizi, Danielle R Isen, Mehdi Tavakoli","doi":"10.18502/jovr.v18i1.12731","DOIUrl":"10.18502/jovr.v18i1.12731","url":null,"abstract":"<p><p>Coronavirus disease 2019 (COVID-19) is a current pandemic caused by SARS-CoV-2 that has vastly affected the whole world. Although respiratory disease is the most common manifestation of COVID-19, the virus can affect multiple organs. Neurotropic aspects of the virus are increasingly unfolding, in so far as some respiratory failures are attributed to brainstem involvement. The neuro-ophthalmic manifestations of COVID-19 and the neuro-ophthalmic side effects of vaccination were reviewed. The major findings are that the SARS-CoV-2 infection commonly causes headaches and ocular pain. It can affect the afferent and efferent visual pathways by ischemic or inflammatory mechanisms. Optic nerve may be the origin of transient or permanent visual loss from papillophlebitis, idiopathic intracranial hypertension, or optic neuritis. Cerebrovascular strokes are not uncommon and may lead to cortical visual impairment or optic nerve infarction. SARS-CoV-2 may affect the pupillomotor pathways, resulting in tonic pupil (Adie's syndrome) or Horner's syndrome. Cranial neuropathies including third, fourth, sixth, and seventh nerve palsies have all been reported. Rhino-orbital mucormycosis superinfections in COVID-19 patients receiving steroids or other immunosuppressive therapies may result in unilateral or bilateral visual loss and ophthalmoplegia. Autoimmune conditions such as Guillain-Barré, Miller-Fisher syndrome, and ocular myasthenia have been reported.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 1","pages":"113-122"},"PeriodicalIF":1.6,"publicationDate":"2023-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9187530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrocorneal Scleral Patch Supported Glue: A Technique for Management of Corneal Perforation and Corneoscleral Melt following Pterygium Surgery. 角膜后巩膜贴片支持胶:处理翼状胬肉术后角膜穿孔和角膜巩膜融化的技术。
IF 2
Journal of Ophthalmic & Vision Research Pub Date : 2023-01-01 DOI: 10.18502/jovr.v18i1.12732
Ashok Sharma, Rajan Sharma, Verinder S Nirankari
{"title":"Retrocorneal Scleral Patch Supported Glue: A Technique for Management of Corneal Perforation and Corneoscleral Melt following Pterygium Surgery.","authors":"Ashok Sharma,&nbsp;Rajan Sharma,&nbsp;Verinder S Nirankari","doi":"10.18502/jovr.v18i1.12732","DOIUrl":"https://doi.org/10.18502/jovr.v18i1.12732","url":null,"abstract":"<p><strong>Purpose: </strong>To describe a new method of treatment of corneal perforation with extensive corneoscleral melt.</p><p><strong>Case report: </strong>A 42-year-old man presented with moderate-sized (3.5 mm) corneal perforation with extensive corneo-limbo-scleral ulceration following bare sclera excision of pterygium. No prior use of antimetabolites or postoperative beta radiation noted. We considered retrocorneal sclera patch supported cyanoacrylate application. The sclera was thinned to one-third thickness and a patch (4.5 <math><mo>×</mo></math> 4.5 mm) was punched. The sclera patch was placed on the iris, behind the corneal perforation, adequately covering it from inside. A minimal amount of adhesive was applied on the retrocorneal sclera patch and margin of corneal perforation. The ulcerating sclera was covered with double layered amniotic membrane. Topical antibiotic, steroid, and cycloplegic drops were instilled thrice daily. Corneal perforation healed and no recurrence occurred during the 18 months' follow-up.</p><p><strong>Conclusion: </strong>Retrocorneal scleral patch supported cyanoacrylate is effective for corneal perforation with corneo-scleral melt.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 1","pages":"123-129"},"PeriodicalIF":2.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020790/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9200062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma. 顽固性皮肤眶周青少年黄色肉芽肿的多角度治疗。
IF 2
Journal of Ophthalmic & Vision Research Pub Date : 2023-01-01 DOI: 10.18502/jovr.v18i1.12733
Alexandra Van Brummen, Sarah Jacobs, Shu Feng, Emily Li, Arash J Amadi
{"title":"A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma.","authors":"Alexandra Van Brummen,&nbsp;Sarah Jacobs,&nbsp;Shu Feng,&nbsp;Emily Li,&nbsp;Arash J Amadi","doi":"10.18502/jovr.v18i1.12733","DOIUrl":"https://doi.org/10.18502/jovr.v18i1.12733","url":null,"abstract":"<p><strong>Purpose: </strong>To demonstrate novel treatments for patients with high juvenile xanthogranuloma (JXG) eyelid lesion burden.</p><p><strong>Case report: </strong>A 14-year-old girl was referred to the oculoplastic surgery service for management of worsening extensive bilateral eyelid and adnexal lesions in the setting of JXG. The patient underwent intra-lesional steroid injections, serial excisions, and reconstruction with skin grafts. She was subsequently treated with CO <math><msub><mrow></mrow> <mn>2</mn></msub> </math> laser-assisted topical steroid application, which resulted in lesion regression.</p><p><strong>Conclusion: </strong>A novel multimodal approach to treatment of severe periocular JXG, incorporating surgical debulking, skin autograft, CO2 laser, and intra-lesional steroids, can be effective for lesion control.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 1","pages":"130-134"},"PeriodicalIF":2.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020784/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9200067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of TRiC-enhanced Actin Folding in Leber Congenital Amaurosis. tricc增强的肌动蛋白折叠在Leber先天性黑朦中的作用。
IF 2
Journal of Ophthalmic & Vision Research Pub Date : 2023-01-01 DOI: 10.18502/jovr.v18i1.12726
Silke Berger, Peter D Currie, Joachim Berger
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