Journal of Ophthalmic & Vision Research最新文献

{"title":"Diffuse Pigment Release in a Patient Undergoing Tumor-Infiltrating Lymphocyte Immunotherapy for Acral Malignant Melanoma.","authors":"Madison Kerley, Niloofar Piri, Aparna Ramasubramanian","doi":"10.18502/jovr.v18i3.13783","DOIUrl":"https://doi.org/10.18502/jovr.v18i3.13783","url":null,"abstract":"This is a Photo Essay and does not have an abstract. Please download the PDF or view the article in HTML.","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 3","pages":"339-341"},"PeriodicalIF":2.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10106040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral Giant Full Thickness Macular Holes: An Infrequent Manifestation of Alport Syndrome.","authors":"Saeed Karimi,&nbsp;Niloofar Mohammad Bagheri Rafsanjani","doi":"10.18502/jovr.v18i3.13781","DOIUrl":"https://doi.org/10.18502/jovr.v18i3.13781","url":null,"abstract":"<p><strong>Purpose: </strong>To report a case of Alport syndrome presenting with bilateral giant full-thickness macular holes, hypertensive chorioretinopathy, and exudative retinal detachment.</p><p><strong>Case report: </strong>A 20 year-old man, a known case of Alport syndrome on hemodialysis, was referred to our clinic with bilateral vision loss initiated about 10 years prior to presentation, which exacerbated in the month prior to our visit. Bilateral large full-thickness macular holes, hypertensive chorioretinopathy, and exudative retinal detachment were detected in fundus examination. The patient had previous genetic counseling confirming the diagnosis of Alport syndrome. During follow-up, macular holes were covered with a thick epiretinal membrane and visual acuity decreased progressively in two weeks. Pars plana vitrectomy was performed in the right eye. Two weeks following surgery, the macular hole was closed and visual acuity improved significantly.</p><p><strong>Conclusion: </strong>Bilateral giant full-thickness macular holes are uncommon presentations of Alport syndrome. The retinal findings may be caused by an inefficient type IV collagen presenting in the Bruch's membrane and in the internal limiting membrane. Pars plana vitrectomy can be considered to repair macular holes in these patients.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 3","pages":"328-333"},"PeriodicalIF":2.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10405639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does Head Tilt Influence Facial Appearance More Than Head Turn?","authors":"Mohamad Reza Akbari,&nbsp;Masoud Khorrami-Nejad,&nbsp;Haleh Kangari,&nbsp;Mohsen Heirani,&nbsp;Alireza Akbarzadeh Baghban,&nbsp;Kiana Raeesdana,&nbsp;Babak Masoomian","doi":"10.18502/jovr.v18i3.13778","DOIUrl":"https://doi.org/10.18502/jovr.v18i3.13778","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the frequency of facial asymmetry parameters in patients with head tilt versus those with head turn.</p><p><strong>Methods: </strong>This cross-sectional comparative study was performed on 155 cases, including 58 patients with congenital pure head turn due to Duane retraction syndrome (DRS), 33 patients with congenital pure head tilt due to upshoot in adduction or DRS, and 64 orthotropic subjects as the control group. The facial appearance was evaluated by computerized analysis of digital photographs of patients' faces. Relative facial size (the ratio of the distance between the external canthus and the corner of the lips of both face sides) and facial angle (the angular difference between a line that connects two external canthi and another line that connects the two corners of the lips) measured as quantitative facial parameters. Qualitative parameters were evaluated by the presence of one-sided face, cheek, and nostril compression; and columella deviation.</p><p><strong>Results: </strong>The facial asymmetry frequency in patients with head tilt, head turn, and orthotropic subjects was observed in 32 (97%), 50 (86.2%), and 22 (34.3%), respectively (<i>P</i> <math><mo><</mo></math> 0.001). In patients with head tilt and head turn, the mean facial angle was 1.78º <math><mo>±</mo></math> 1.01º and 1.19º <math><mo>±</mo></math> 0.84º, respectively (<i>P</i> = 0.004) and the mean relative facial size was 1.027 <math><mo>±</mo></math> 0.018 and 1.018 <math><mo>±</mo></math> 0.014, respectively (<i>P</i> = 0.018). The frequencies of one-sided nostril compression, cheek compression, face compression, and columella deviation in patients with pure head tilt were found in 19 (58%), 21 (64%), 19 (58%), and 19 (58%) patients, respectively, and in patients with pure head turn the frequencies were observed in 42 (72%), 37 (63%), 27 (47%), and 43 (74%), respectively. All quantitative and qualitative facial asymmetry parameters and facial asymmetry frequencies were significantly higher in head tilt and head turn patients as compared to the control group (<i>P</i> <math><mo><</mo></math> 0.001).</p><p><strong>Conclusion: </strong>All facial asymmetry parameters in patients with head tilt and head turn were significantly higher than orthotropic subjects. The quantitative parameters such as relative facial size and facial angle were significantly higher in patients with pure head tilt than pure head turn. The results revealed that pure head tilt was associated with a higher prevalence of facial asymmetry than pure head turn.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 3","pages":"297-305"},"PeriodicalIF":2.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10050023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgically Managed Orbital Tumors: A Case Series from a Referral Center in Iran.","authors":"Arman Mashayekhi","doi":"10.18502/jovr.v18i2.13178","DOIUrl":"10.18502/jovr.v18i2.13178","url":null,"abstract":"","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"141-142"},"PeriodicalIF":1.6,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9839598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pachychoroid Spectrum Disorders: An Updated Review.","authors":"Richard B Brown, Sashwanthi Mohan, Jay Chhablani","doi":"10.18502/jovr.v18i2.13188","DOIUrl":"10.18502/jovr.v18i2.13188","url":null,"abstract":"<p><p>Pachychoroid disease spectrum is a recent term that has been associated with an increasing number of phenotypes. This review discusses updated findings for each of the typical pachychoroid entities (central serous chorioretinopathy, pachychoroid pigment epitheliopathy, pachychoroid neovasculopathy, polypoidal choroidal vasculopathy, peripapillary pachychoroid syndrome, and focal choroidal excavation), as well as two relatively new additions (peripapillary pachychoroid neovasculopathy and peripheral exudative hemorrhagic chorioretinopathy). Here, we discuss the potential pathogenic mechanisms for these diseases and relevant imaging updates. Finally, we argue for a consistent classification scheme for these entities.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"212-229"},"PeriodicalIF":1.6,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9470867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inverted ILM Flap Technique in Optic Disc Pit Maculopathy.","authors":"Ali Tavallali, Yasaman Sadeghi, Seyed-Hossein Abtahi, Hosein Nouri, Sanam Samadikhadem, Mitra Rezaei, Mehdi Mazloumi","doi":"10.18502/jovr.v18i2.13189","DOIUrl":"10.18502/jovr.v18i2.13189","url":null,"abstract":"<p><strong>Purpose: </strong>To present the outcome of optic disc pit maculopathy (ODPM) managed successfully with an inverted internal limiting membrane (ILM) flap over the optic disc. A narrative review of ODPM pathogenesis and surgical management techniques are also provided.</p><p><strong>Case report: </strong>This prospective interventional case series included three eyes of three adult patients (25-39 years old) with unilateral ODPM and a mean duration of unilaterally decreased visual acuity of 7.33 <math><mo>±</mo></math> 2.40 months (4-12 months). The pars plana vitrectomy with posterior vitreous detachment induction was performed on eyes, followed by an inverted ILM flap insertion over the optic disc and gas tamponade. Patients were followed for 7-16 weeks postoperatively; best-corrected visual acuity (BCVA) improved dramatically in one patient from 2/200 to 20/25. BCVA in other patients improved two and three lines - to 20/50 and 20/30, respectively. A significant anatomical improvement was achieved in all three eyes, and no complication was detected throughout the follow-up period.</p><p><strong>Conclusion: </strong>Vitrectomy with inverted ILM flap insertion over the optic disc is safe and can yield favorable anatomical improvement in patients with ODPM.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"230-239"},"PeriodicalIF":2.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172795/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9822864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eye Care in Young Children: A Parents' Perspective of Access and Barriers.","authors":"Ali M Alsaqr","doi":"10.18502/jovr.v18i2.13186","DOIUrl":"https://doi.org/10.18502/jovr.v18i2.13186","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate parental perspectives of accessing eye care for children aged under seven years.</p><p><strong>Methods: </strong>The survey was conducted during September 2020 to March 2021 using online applications and distributed to parents whose children were between the ages of three and seven years. The survey included parents' background, their knowledge of the provision of eye-care services, and the possible barriers that existed to access eye-care services. The relationship between parents' knowledge, barrier scores, level of parental education, and demographic or socioeconomic status was assessed using nonparametric tests.</p><p><strong>Results: </strong>In total, 1037 questionnaires were completed. The respondents were from 50 cities across Saudi regions. The participants' age was 39 <math><mo>±</mo></math> 7.5 years, and 54% of them had at least one child under the age of seven (<i>n</i> = 564). Further, 47% had not taken their children for vision screening at reception/year one (<i>n</i> = 467). In addition, 65% of them were not aware of the mandatory screening program at reception/year <i>1</i>; whereas, only 20% (<i>n</i> = 207) knew how to access eye-care services; and only 39% of the children had undergone any kind of eye or vision test. The pathways to eye care and the cost of eye services/glasses were the main limitations. The parents' responses were significantly influenced by their demographic and socioeconomic characteristics (Kruskal Wallis, <i>P</i> <math><mo><</mo></math> 0.05).</p><p><strong>Conclusion: </strong>There was a need for enhancing parent information on how to access eye care for young children and the currently available vision screening programs. Finally, a national protocol to cover the cost of the eye exam as well as spectacle prescription shall be proposed as a mean of incentive.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"192-201"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9523705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Phacoemulsification on Intraocular Pressure in Eyes with Functioning Tube Shunts.","authors":"Wesam Shamseldin Shalaby,&nbsp;Sonali Patel,&nbsp;Sophia S Lam,&nbsp;Allen Ganjei,&nbsp;Aakriti Garg Shukla,&nbsp;Natasha Kolomeyer,&nbsp;Daniel Lee,&nbsp;L Jay Katz,&nbsp;Marlene R Moster,&nbsp;Jonathan Myers,&nbsp;Reza Razeghinejad","doi":"10.18502/jovr.v18i2.13180","DOIUrl":"https://doi.org/10.18502/jovr.v18i2.13180","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effect of phacoemulsification on intraocular pressure (IOP) in eyes with functioning tube shunts.</p><p><strong>Methods: </strong>This was a retrospective chart review of primary open-angle glaucoma (POAG) patients with a functioning tube who underwent phacoemulsification and had <math><mo>≥</mo></math>24 months of follow-up. The primary end point was defined as surgical failure (IOP <math><mo>></mo></math> 21 mmHg) at month 24, progression to no light perception (NLP) vision, glaucoma reoperation, or implant removal. Surgical failure defined as IOP <math><mo>></mo></math>18 and <math><mo>></mo></math>15 mmHg, changes in visual acuity (VA), IOP, and number of medications were assessed.</p><p><strong>Results: </strong>Twenty-seven eyes of 27 patients with moderate or severe POAG were included. The mean age of the patients was 64.2 <math><mo>±</mo></math> 10.8 years. The interval between the tube shunt and phacoemulsification was 28.8 <math><mo>±</mo></math> 25.0 months. At the end of the study, four (14.8%) eyes met the failure criteria; the average time to failure was 9.3 <math><mo>±</mo></math> 3.8 months. The causes of failure were high IOP in two (50.0%) and glaucoma reoperation in two (50.0%) eyes; however, no eyes progressed to NLP vision. Surgical failure defined as IOP <math><mo>></mo></math>18 and <math><mo>></mo></math>15 mmHg showed an increasing failure rate (18.5% and 48.5%, respectively).Themean IOP and medications number remained stable at month 24 compared to baseline (<i>P</i> = 0.131 and <i>P</i> = 0.302, respectively). Initially, VA showed improvement, with the greatest improvement at 6 months (<i>P</i> = 0.001), but at 24 months the improvement was no longer significant (<i>P</i> = 0.430).</p><p><strong>Conclusion: </strong>Phacoemulsification in patients with functioning tubes did not change the mean IOP in most of the patients (86.2%); the number of medications also did not increase.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"150-156"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172799/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9470868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posterior Microphthalmos Pigmentary Retinopathy Syndrome.","authors":"Syed Saifuddin Adeel,&nbsp;Syed Mohideen Ka,&nbsp;Anuj Sharma,&nbsp;Vinit J Shah,&nbsp;Adheesh Shetty","doi":"10.18502/jovr.v18i2.13190","DOIUrl":"https://doi.org/10.18502/jovr.v18i2.13190","url":null,"abstract":"<p><strong>Purpose: </strong>To report a case of a rare disease entity Posterior Microphthalmos Pigmentary Retinopathy Syndrome (PMPRS) in a 47-year-old female with a brief review of literature.</p><p><strong>Case report: </strong>A 47-year-old woman presented with a history of defective vision with an associated difficulty in night vision. Clinical workup was done, which included a thorough ocular examination showing diffuse pigmentary mottling of fundus, ocular biometry showing short axial length with normal anterior segment dimensions, electroretinography showing extinguished response, optical coherence tomography showing foveoschisis, and ultrasonography showing thickened sclera-choroidal complex. Findings were consistent with those reported by other authors with PMPRS.</p><p><strong>Conclusion: </strong>Posterior microphthalmia with or without other ocular and systemic associations should be suspected in cases with high hyperopia. It is mandatory to carefully examine the patient at presentation and close follow-ups are needed to maintain visual function.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"240-244"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172798/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9822860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Punctal Occlusion; Combined Lacrimal Canaliculi Cauterization and Punctal Suturing for Severe Dry Eye.","authors":"Kohei Kuroda,&nbsp;Hiroshi Toshida,&nbsp;Yoko Sorita,&nbsp;Kohei Ichikawa,&nbsp;Yusuke Matsuzaki,&nbsp;Toshihiko Ohta","doi":"10.18502/jovr.v18i2.13179","DOIUrl":"https://doi.org/10.18502/jovr.v18i2.13179","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the treatment outcome of surgical punctal occlusion with combined canaliculi ablation and punctal suturing in patients with severe dry eye.</p><p><strong>Methods: </strong>Eleven eyes of seven patients were diagnosed with severe dry eye with decreased lacrimal secretion and were refractory to treatment with various eye drops and/or had repeatedly experienced loss of punctal plugs, and continued to experience subjective symptoms received surgical punctal occlusion. In 20 puncta, lacrimal canaliculi ablation was performed along the entire length of the lacrimal canaliculus where a diathermy needle could be inserted. After resection of the annulus fibrosus in the peri-punctal area, tight cross-stitch suturing of the puncta was performed with 8-0 absorbent thread. Visual acuity, corneal staining score according to the area (A) and density (D) classification, and Schirmer tear test (STT); tear break up time (tBUT); and subjective symptoms assessed by the University of North Carolina (UNC) and Dry Eye Management Scale were compared before and one year after surgery.</p><p><strong>Results: </strong>Recanalization occurred in 1/20 puncta (5.0% at month 5) in 1/11 eyes. Student's <i>t</i>-test showed significant improvement at one year compared with preoperative values for LogMAR value (<i>P</i> = 0.019), corneal staining score A (<i>P</i> = 0.00003) and D (<i>P</i> = 0.0003), STT (<i>P</i> = 0.004), and subjective symptoms (<i>P</i> = 0.015). No change was shown in tBUT and no serious adverse event occurred.</p><p><strong>Conclusion: </strong>This improved, minimally invasive surgical procedure has a low recanalization rate and achieves both objective and subjective improvements at one year.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 2","pages":"143-149"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9822859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}