Alexandra Van Brummen, Sarah Jacobs, Shu Feng, Emily Li, Arash J Amadi
{"title":"顽固性皮肤眶周青少年黄色肉芽肿的多角度治疗。","authors":"Alexandra Van Brummen, Sarah Jacobs, Shu Feng, Emily Li, Arash J Amadi","doi":"10.18502/jovr.v18i1.12733","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To demonstrate novel treatments for patients with high juvenile xanthogranuloma (JXG) eyelid lesion burden.</p><p><strong>Case report: </strong>A 14-year-old girl was referred to the oculoplastic surgery service for management of worsening extensive bilateral eyelid and adnexal lesions in the setting of JXG. The patient underwent intra-lesional steroid injections, serial excisions, and reconstruction with skin grafts. She was subsequently treated with CO <math><msub><mrow></mrow> <mn>2</mn></msub> </math> laser-assisted topical steroid application, which resulted in lesion regression.</p><p><strong>Conclusion: </strong>A novel multimodal approach to treatment of severe periocular JXG, incorporating surgical debulking, skin autograft, CO2 laser, and intra-lesional steroids, can be effective for lesion control.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 1","pages":"130-134"},"PeriodicalIF":1.6000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020784/pdf/","citationCount":"0","resultStr":"{\"title\":\"A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma.\",\"authors\":\"Alexandra Van Brummen, Sarah Jacobs, Shu Feng, Emily Li, Arash J Amadi\",\"doi\":\"10.18502/jovr.v18i1.12733\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To demonstrate novel treatments for patients with high juvenile xanthogranuloma (JXG) eyelid lesion burden.</p><p><strong>Case report: </strong>A 14-year-old girl was referred to the oculoplastic surgery service for management of worsening extensive bilateral eyelid and adnexal lesions in the setting of JXG. The patient underwent intra-lesional steroid injections, serial excisions, and reconstruction with skin grafts. She was subsequently treated with CO <math><msub><mrow></mrow> <mn>2</mn></msub> </math> laser-assisted topical steroid application, which resulted in lesion regression.</p><p><strong>Conclusion: </strong>A novel multimodal approach to treatment of severe periocular JXG, incorporating surgical debulking, skin autograft, CO2 laser, and intra-lesional steroids, can be effective for lesion control.</p>\",\"PeriodicalId\":16586,\"journal\":{\"name\":\"Journal of Ophthalmic & Vision Research\",\"volume\":\"18 1\",\"pages\":\"130-134\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020784/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Ophthalmic & Vision Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18502/jovr.v18i1.12733\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Ophthalmic & Vision Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18502/jovr.v18i1.12733","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma.
Purpose: To demonstrate novel treatments for patients with high juvenile xanthogranuloma (JXG) eyelid lesion burden.
Case report: A 14-year-old girl was referred to the oculoplastic surgery service for management of worsening extensive bilateral eyelid and adnexal lesions in the setting of JXG. The patient underwent intra-lesional steroid injections, serial excisions, and reconstruction with skin grafts. She was subsequently treated with CO laser-assisted topical steroid application, which resulted in lesion regression.
Conclusion: A novel multimodal approach to treatment of severe periocular JXG, incorporating surgical debulking, skin autograft, CO2 laser, and intra-lesional steroids, can be effective for lesion control.
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