Dumitru Sutoi, Alexandru Cristian Cindrea, Daian Ionel Popa, Cosmin Iosif Trebuian, Carmen Williams, Maria Sutoi, Alexandru Bogdan Puscas, Adina Maria Marza, Florina Buleu, Bogdan Chiu, George Marin, Vlad Mulcutan Chis, Anda Ciontos, Luca Darie Sabau, Ovidiu Alexandru Mederle
{"title":"Impact of hands-on workshops on future medical students' motivation, confidence, and career aspirations: an observational study.","authors":"Dumitru Sutoi, Alexandru Cristian Cindrea, Daian Ionel Popa, Cosmin Iosif Trebuian, Carmen Williams, Maria Sutoi, Alexandru Bogdan Puscas, Adina Maria Marza, Florina Buleu, Bogdan Chiu, George Marin, Vlad Mulcutan Chis, Anda Ciontos, Luca Darie Sabau, Ovidiu Alexandru Mederle","doi":"10.25122/jml-2025-0030","DOIUrl":"10.25122/jml-2025-0030","url":null,"abstract":"<p><p>Workshops serve as an extrinsic motivational tool for medical students, enhancing their knowledge, self-confidence, and practical skills. These workshops could have a similar impact on future medical students, who may have various reasons for their aspiration to follow a career in medicine. The main goal of our study was to demonstrate that participating in hands-on workshops boosts the motivation of future medical students to work toward a career in medicine. The second goal was to evaluate the amount of first aid assistance participants provided, their willingness to deliver first aid, and the impact on self-perceived confidence in their practical skills after attending this experience. Workshops were conducted across multiple cities, engaging 540 participants between March and November 2024. At year-end, a custom questionnaire assessed their motivation, self-confidence, and medical career aspirations. A total of 186 participants met the inclusion criteria and were analyzed. Participants had a median age of 18.5 years (18-19.75) and graduated high school (55.4%). Most chose to follow medicine due to a strong desire to help or an exclusive desire to practice in this field. Significant increases in respondents' Likert scale ratings were observed before and after the workshops (<i>P</i> < 0.001, Wilcoxon signed-rank test). No significant differences were found when comparing responses between different workshops. In conclusion, the results of the motivating factors align with the trends in other high-income countries. Also, workshops serve as an extrinsic motivational source, increasing students' self-confidence and theoretical and practical knowledge.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 2","pages":"147-154"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11932505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The impact of endometriosis on patients' quality of sexual life.","authors":"Mihaela Amza, Romina-Marina Sima, Ileana-Maria Conea, Tina-Ioana Bobei, Fernanda-Ecaterina Augustin, Liana Pleş","doi":"10.25122/jml-2024-0262","DOIUrl":"10.25122/jml-2024-0262","url":null,"abstract":"<p><p>The objective of this study was to evaluate the prevalence and impact of female sexual dysfunction and sexual distress in women with endometriosis. This retrospective, analytical, observational study included patients diagnosed with ovarian endometriomas who underwent surgery to remove endometriosis lesions. The impact of endometriosis on the quality of sexual lives of patients before and after surgery was analyzed using a self-administered questionnaire consisting of 20 closed-ended questions. The study included 70 patients with endometriosis with a mean age of 32.70 ± 7.39 years. The majority of patients reported that the diagnosis of endometriosis negatively influenced their quality of sexual life (65.7%). Most patients (88.6%) experienced dyspareunia before surgery. A total of 36 patients (51.4%) stated that they had difficulty in obtaining pleasure during sexual intercourse. The intensity of dyspareunia had an important negative effect on the quality of sexual life of the patients. Following surgery, most patients (81.4%) reported improvements in their sexual quality of life, with a statistically significant reduction in pain intensity during intercourse (<i>P</i> < 0.001). These findings suggest that endometriosis may contribute to sexual avoidance and diminished pleasure. Surgical removal of endometriosis lesions significantly improved sexual quality of life, particularly by reducing dyspareunia intensity.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 2","pages":"90-93"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11932512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exercise, myonectin response, and insulin resistance among overweight, obese and healthy individuals: a systematic review and narrative synthesis.","authors":"Aysha Mohamed Mohamed Alsahi Alzaabi, Ramprasad Muthukrishnan, Marwan Ismail, Praveen Kumar Kandakurthi, Satheeskumar Durairaj, Shanmugam Sukumar, Kumaraguruparan Gopal","doi":"10.25122/jml-2024-0277","DOIUrl":"10.25122/jml-2024-0277","url":null,"abstract":"<p><p>Myonectin, a novel muscle-derived peptide or myokine, has been implicated in glucose and lipid homeostasis through its autocrine, paracrine, and endocrine functions. This review aimed to explore the impact of structured exercise interventions on myonectin levels and insulin resistance indicators in healthy individuals and those living with overweight or obesity. We performed a search of PubMed, Science Direct, CINAHL, TRIP Database, Cochrane Library, and Google Scholar for studies published until July 2022. The key terms used were \"prediabetes\", \"overweight\", \"obesity\", \"myonectin\", \"Complement 1q / tumor necrosis factor-related protein 5 (CTRP5 or C1qTNF5)\", \"erythroferrone\", and \"exercise\". Eight studies investigated the effects of exercise on myonectin levels and insulin resistance, measured through the Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), in individuals who were overweight or obese, while six studies focused on those without these conditions. After data extraction, narrative qualitative synthesis and risk of bias analysis were performed. Findings indicate that structured aerobic or combined aerobic and resistance training at moderate intensity over 8-12 weeks led to significant increases in myonectin levels and reductions in insulin resistance, particularly among women who were overweight or obese. However, data was limited by heterogeneous age and gender groups' metabolic profiles and variability in exercise protocols. Myonectin response to exercise in healthy adults remains unclear due to baseline metabolic variability, though some improvements in the glucose-insulin axis were noted. This review suggests that myonectin may serve as a valuable biomarker to assess the impact of exercise on insulin sensitivity in individuals at risk of diabetes with overweight or obesity.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 2","pages":"73-89"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11932511/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vlad Paic, Petru Adrian Radu, Anca Tigora, Mihai Zurzu, Mircea Bratucu, Costin Pasnicu, Alexandra Purcaru, Petru Stavar, Valeriu Surlin, Dan Cartu, Daniela Marinescu, Traean Burcos, Florian Popa, Victor Strambu, Dragos Garofil
{"title":"Collagen metabolism and incisional hernia recurrence: a comparative study between oncologic and non-oncologic patients.","authors":"Vlad Paic, Petru Adrian Radu, Anca Tigora, Mihai Zurzu, Mircea Bratucu, Costin Pasnicu, Alexandra Purcaru, Petru Stavar, Valeriu Surlin, Dan Cartu, Daniela Marinescu, Traean Burcos, Florian Popa, Victor Strambu, Dragos Garofil","doi":"10.25122/jml-2025-0028","DOIUrl":"10.25122/jml-2025-0028","url":null,"abstract":"<p><p>A significant challenge in incisional hernia repair is the recurrence risk, which may be influenced by the structural integrity of collagen within the tissue. This study investigated the role of collagen metabolism in hernia recurrence by comparing oncologic and non-oncologic patients, focusing on collagen I/III ratios and their impact on tissue strength and surgical outcomes. A comparative clinical study was conducted on 50 patients (30 oncologic, 20 non-oncologic) undergoing incisional hernia repair. Collagen composition was analyzed using stereomicroscopy, and statistical comparisons were performed using independent <i>t</i>-tests and chi-square tests to assess differences in recurrence rates and tissue properties between groups. Results indicated that oncologic patients had significantly lower collagen I/III ratios (<i>P</i> < 0.001), suggesting structurally weaker tissue, which correlated with higher recurrence rates (18% in oncologic vs. 10% in non-oncologic patients). Furthermore, the sublay mesh repair technique demonstrated superior outcomes with lower recurrence rates compared to onlay repair, reinforcing its role in mitigating complications associated with poor collagen integrity. The study results indicated that oncologic patients had impaired collagen remodeling, contributing to an increased risk of recurrence. Individualized surgical strategies, including targeted preoperative interventions, may help mitigate these risks and enhance patient outcomes. Given the observed disparities, further research is warranted to explore targeted therapeutic approaches that enhance tissue quality and improve long-term surgical success in high-risk patient populations.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 2","pages":"133-139"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11932504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diana-Theodora Morgos, Lucian-George Eftimie, Horia Nicolae, Remus Iulian Nica, Constantin Stefani, Daniela Miricescu, Adrian Tulin, Florin Mihail Filipoiu
{"title":"Spotting the clues: cluster of differentiation-a perspective of immune response intertwined with dysautonomia in colon cancer - a prospective cohort study.","authors":"Diana-Theodora Morgos, Lucian-George Eftimie, Horia Nicolae, Remus Iulian Nica, Constantin Stefani, Daniela Miricescu, Adrian Tulin, Florin Mihail Filipoiu","doi":"10.25122/jml-2025-0014","DOIUrl":"10.25122/jml-2025-0014","url":null,"abstract":"<p><p>Dysautonomia, a parasympathetic-sympathetic imbalance, has clinical and public health consequences. Colon neoplasm is linked to dysautonomia through a complex interplay between the two conditions. In this prospective cohort study, we evaluated 18 patients divided into three groups: six patients with both colon cancer and dysautonomia, six patients with colon cancer without dysautonomia, and six patients with dysautonomia only (control group). Dysautonomia was defined by the presence of orthostatic hypotension, a non-increased or dropped heart rate, and various autonomic symptoms. During abdominal surgery, tissue samples from the celiac ganglion were collected and analyzed using immunohistochemistry (IHC). Our findings revealed a significant correlation between IHC marker expression in colon cancer and dysautonomia (control) (r = 0.927, <i>P</i> = 0.008). ANOVA results confirmed that the model was significant and that the dysautonomia group (control) had a significant effect on the independent variables (colon cancer or colon cancer + dysautonomia). The study proposes that a shared immunological mechanism underlies both dysautonomia and colon cancer, suggesting that the immune system plays a crucial role in the development or progression of these two conditions.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 2","pages":"125-132"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11932503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patients' satisfaction with healthcare services in Al-Baha, Saudi Arabia: a cross-sectional study.","authors":"Ramy Hassan Agwa, Turki Alkully, Warda Othman, Sahar Abdulrahman Alghamdi, Haya Abdulaziz Alzahrani, Nada Saleh Algamdi, Yahya Saeed Al Zahrani, Abdulrhman Saleh Alzhrani","doi":"10.25122/jml-2024-0391","DOIUrl":"10.25122/jml-2024-0391","url":null,"abstract":"<p><p>Patient satisfaction is crucial in assessing healthcare quality, encompassing factors such as continuity of care, waiting times, and physician-patient communication. This study evaluated patient satisfaction with healthcare services and determined the main reasons for low self-reported quality. A cross-sectional study was conducted in the Al-Baha region, including Saudi adults aged 18 to 60 who visited public or private health centers. Data were collected using a modified patient satisfaction questionnaire. The Chi-square test and logistic regression were utilized. Out of 388 participants, 55.2% were women. Most were highly educated and resided in Al-Baha. Long waiting times (38.4%) and appointment difficulties (25.8%) were the most common drawbacks. Men and Al-Baha residents had higher satisfaction scores. Higher income was linked to better accessibility and convenience scores. Satisfaction was higher among patients at private hospitals. The study provides insights into patient satisfaction in Al-Baha, highlighting the need to reduce waiting times and improve appointment systems to enhance healthcare quality.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 2","pages":"94-99"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11932509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Computed tomography accuracy and features in detecting open globe injuries in patients with ocular trauma: a systematic review and meta-analysis.","authors":"Ghada Aljuhani, Nahla Aljuhani","doi":"10.25122/jml-2024-0353","DOIUrl":"10.25122/jml-2024-0353","url":null,"abstract":"<p><p>Open globe injuries (OGIs) can have devastating impacts on patients' lives. Early detection of OGIs is crucial for improving outcomes, as any delay in treatment can result in significant consequences. Radiological imaging, particularly computed tomography (CT), aids ophthalmologists in diagnosing this condition, especially in challenging cases. This literature review aimed to evaluate the accuracy of CT scans in identifying features of OGIs based on current evidence. This systematic review adhered to the 2020 Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol. PubMed and EBSCOhost databases were searched using the keywords 'rupture globe' or 'open globe' and 'computed tomography' or 'CT'. Articles published in English between 1990 and 2023 were considered for inclusion, whereas review articles were excluded from the analysis. The initial search yielded 169 studies, and nine studies were included in the final screening. This review encompassed 917 eyes. The pooled specificity of the CT scan in detecting OGIs among patients with ocular trauma was 0.94 with 95% CI (0.92-0.96), and the pooled sensitivity was 0.77 with 95% CI (0.72-0.81). The area under the curve was 0.91, indicating the excellent ability of the CT scan to detect open globe injury. CT scans demonstrated high diagnostic accuracy for detecting OGI. While CT is highly effective in identifying ocular trauma, careful interpretations remain essential. Additional studies with larger sample sizes are recommended to refine its diagnostic role further.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 1","pages":"20-28"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891614/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Flor Daniela Alday-Montañez, Daniel Dickens-Terrazas, Gloria Erika Mejia-Carmona, Elisa Robles-Escajeda, Robert Arthur Kirken, Alfonso Enrique Bencomo-Alvarez, Victor Josue Carrasco-Urrutia, Naun Lobo-Galo, Luis Fernando Plenge-Tellechea, Ángel Gabriel Diaz-Sanchez, Alejandro Martínez-Martínez
{"title":"Pathogenic variants in <i>BRCA1</i> and <i>BRCA2</i> genes associated with female breast and ovarian cancer in the Mexican population.","authors":"Flor Daniela Alday-Montañez, Daniel Dickens-Terrazas, Gloria Erika Mejia-Carmona, Elisa Robles-Escajeda, Robert Arthur Kirken, Alfonso Enrique Bencomo-Alvarez, Victor Josue Carrasco-Urrutia, Naun Lobo-Galo, Luis Fernando Plenge-Tellechea, Ángel Gabriel Diaz-Sanchez, Alejandro Martínez-Martínez","doi":"10.25122/jml-2024-0213","DOIUrl":"10.25122/jml-2024-0213","url":null,"abstract":"<p><p>Breast and ovarian cancers are significant global health challenges, with inherited variations in breast cancer gene 1 (<i>BRCA1</i>) and breast cancer gene 2 (<i>BRCA2</i>) substantially increasing the risk, aggressiveness, and early onset of these diseases. This work aimed to examine pathogenic variants (PVs) in <i>BRCA1</i> and <i>BRCA2</i> databases that include Mexican populations. A systematic review of literature and data mining spanning from 2002 to 2023 was conducted. Articles published in journals indexed in SCImago quartiles Q1 to Q4 were screened. Databases were paired, standardized, and enriched with data from reputable global platforms: Genome Data Viewer, dbSNP, ClinVar, gnomAD browser, Breast Cancer Information Core (BIC), ClinGen, Varsome, Human Genome Variation Society (HGVS), Bioproject, Ensembl, Gene NIH NCIB, UniProt, and BRCA Exchange. Outcomes included data from 9,026 Mexican genotypes, identifying 657 PVs. Genetic mapping revealed certain exons, notably exon 10 of <i>BRCA1</i> and exon 11 of <i>BRCA2</i>, as highly mutagenic hot spots. The most frequent alteration was a large deletion in <i>BRCA1</i> (ex9-12del), associated with a founder effect originating from a common Mexican ancestor. Finally, we constructed a genetic map containing all the single nucleotide variants (SNVs) and large rearrangements presented in the analyzed databases.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 1","pages":"38-47"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891617/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diana-Theodora Morgos, Lucian-George Eftimie, Horia Nicolae, Remus Iulian Nica, Constantin Stefani, Daniela Miricescu, Adrian Tulin, Florin Mihail Filipoiu
{"title":"The celiac ganglia and trunk: an assessment of anatomical variants and their clinical relevance.","authors":"Diana-Theodora Morgos, Lucian-George Eftimie, Horia Nicolae, Remus Iulian Nica, Constantin Stefani, Daniela Miricescu, Adrian Tulin, Florin Mihail Filipoiu","doi":"10.25122/jml-2025-0015","DOIUrl":"10.25122/jml-2025-0015","url":null,"abstract":"<p><p>The celiac ganglia are a network of nerve fibers that regulate various functions related to digestion, while the celiac trunk is a major artery that supplies oxygenated blood to the stomach, small intestine, and other organs in the upper abdominal region. Anatomical variants of these structures are common and can have significant implications for surgical and medical procedures. This prospective observational study was conducted over one year and included 300 patients (aged 45-75 years) with a history of peripheral arterial disease, evaluated at Dr. Carol Davila Central Military Emergency Hospital Bucharest, Romania, using a Philips Spectral CT 7500. The study identified three major anatomical variants of the celiac trunk, each associated with different positional distributions of the celiac ganglia. In cases where the celiac trunk presented as a hepatosplenic trunk with the left gastric artery originating from the abdominal aorta, the lateral position of the celiac ganglia was most prevalent. When the hepatosplenic trunk included the left gastric artery arising from the splenic artery, the postero-lateral position of the celiac ganglia was the most frequently observed. In patients with a hepatogastric trunk, where the splenic artery originated from the superior mesenteric artery, the lateral position of the celiac ganglia was again the most common. Statistical analysis reveals a t-statistic of 7.391 and 11.319 with a P value of 0.002. This article reviewed the anatomical variants of the celiac ganglia and their anatomical variants, highlighting their prevalence, clinical significance, and implications for surgical and interventional procedures.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 1","pages":"60-66"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emad Uddin Siddiqui, Noor Ul Ain, Abid Ali Jamali, Ghazala Irfan Kazi, Tooba Siddiqui
{"title":"Outcomes of pediatric patients prioritized as critical (P1/P2) by registered triage nurses from a tertiary care hospital in a low-middle-income country.","authors":"Emad Uddin Siddiqui, Noor Ul Ain, Abid Ali Jamali, Ghazala Irfan Kazi, Tooba Siddiqui","doi":"10.25122/jml-2024-0228","DOIUrl":"10.25122/jml-2024-0228","url":null,"abstract":"<p><p>Triage in emergency departments (EDs) is a dynamic decision-making process to prioritize patients based on their medical care needs. The Emergency Severity Index (ESI) is a simple-to-use, five-level triage system that categorizes ED patients according to clinical urgency. The triage nurse's ability to obtain a brief history and rapidly assess clinical urgency is crucial for ensuring safe and efficient emergency care. This study aimed to assess the ability of registered triage nurses to accurately identify pediatric patients classified as Priority 1 (P1) and Priority 2 (P2) under the ESI, ensuring timely, life-saving interventions for critically ill children. A prospective chart review was conducted over six months, including all pediatric patients (aged 0-16 years) presenting to the ED and categorized as P1 or P2. Demographic data such as age, weight, gender, presenting complaints, vital signs at presentation, treatments administered in the ED, length of stay, and final disposition (admitted or discharged) were collected. Data were presented as mean ± SD or percentages with ranges. The association between the triage category and outcomes was assessed using the chi-square test. A total of 503 pediatric cases were included, with a mean age of 2.96 ± 3.79 years. The cohort comprised 311 male (62%) and 192 female patients (38%), with 250 patients (50%) under one year of age. Most patients (<i>n</i> = 308, 61%) were categorized as P2. Respiratory difficulties and fever were identified in 167 (33%) children, followed by cough/shortness of breath (SOB), fall/road traffic accident (RTA), and seizures. Among P1 cases, 11 patients (2%) required ventilatory support. A total of 384 patients (76%) were admitted to the hospital, with 297 (60%) admitted to general wards, primarily P2 cases. Significant associations were observed between triage category and outcomes, including seizures/febrile fits (P1: 20.5% vs. P2: 11.4%, <i>P</i> = 0.005) and pediatric intensive care unit (PICU) admissions (P1: 26.1% vs. P2: 5.1%, <i>P</i> < 0.001). Outcome measurements, like hospitalization, mode of admission (PICU or special care unit), mortality, length of stay in ED, cost of ED stays, and resources utilized, were all dependent on the initial triage categorization. The ESI triage system demonstrated its predictive value in determining urgency and guiding subsequent clinical decisions.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 1","pages":"48-53"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}