Journal of Medicine and Life最新文献_第7页

Epidemiological trends of HSV-1 and HSV-2 Central Nervous System Infections: A Retrospective Analysis from 2018 to 2023 from Saudi Arabia. HSV-1 和 HSV-2 中枢神经系统感染的流行病学趋势：2018年至2023年沙特阿拉伯的回顾性分析。

Journal of Medicine and Life Pub Date : 2025-01-01 DOI: 10.25122/jml-2024-0377

Abdulaziz Alhazmi, Amal Gharawi, Khalid Alameer, Bandar Abuageelah, Ehab Hakami, Taif Zogel, Abdullah Almalki, Ebhar Magrashi, Wafa Alharbi, Ramis Manni, Atheer Buayti, Ali Qasem, Tareq Khawaji, Moayad Haddad, Nabil Dhayhi

{"title":"Epidemiological trends of HSV-1 and HSV-2 Central Nervous System Infections: A Retrospective Analysis from 2018 to 2023 from Saudi Arabia.","authors":"Abdulaziz Alhazmi, Amal Gharawi, Khalid Alameer, Bandar Abuageelah, Ehab Hakami, Taif Zogel, Abdullah Almalki, Ebhar Magrashi, Wafa Alharbi, Ramis Manni, Atheer Buayti, Ali Qasem, Tareq Khawaji, Moayad Haddad, Nabil Dhayhi","doi":"10.25122/jml-2024-0377","DOIUrl":"10.25122/jml-2024-0377","url":null,"abstract":"Herpes Simplex Virus (HSV) types 1 and 2 are significant etiologies to central nervous system (CNS) infections, leading to potential severe neurological consequences. Despite their global impact, our region's data on the epidemiology of HSV CNS infections remains limited. This study assessed the epidemiology and diagnostic trends of HSV-1 and HSV-2 CNS infections in a tertiary hospital in Southwestern Saudi Arabia from 2018 to 2023. A retrospective study was conducted using data from cerebrospinal fluid (CSF) samples collected from patients with suspected CNS infection between 2018 and 2023. Polymerase Chain Reaction (PCR) results for detecting HSV-1 and HSV-2, performed as part of routine clinical diagnostics, were analyzed. Data on patient demographics, specimen collection times (including months and years), laboratory processing times, and seasonal trends were collected and analyzed using descriptive statistics and univariate analysis. Of the 280 samples, 11.0% were positive for HSV, with 10.0% positive for HSV-1 and 1.0% for HSV-2. Most HSV-positive cases were found in patients aged ≥51 years (27.0%). Peak detection occurred in 2020, with seasonal spikes in May and September. The turnaround time significantly varied, with the shortest laboratory turnaround time for PCR results recorded in 2020 (35.54 hours), while the longest was in 2021 (167.38 hours). This study reports an important burden of HSV-related CNS infections in Southwestern Saudi Arabia, indicating the importance of timely diagnosis through PCR testing. Our findings highlight the need for improved diagnostic workflows and enhanced epidemiological surveillance. Future research should explore broader regional and clinical data related to HSV CNS infection epidemiology.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 1","pages":"54-59"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891609/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reviewing the complexities of horseshoe kidney: insights into embryogenesis and surgical considerations. 回顾马蹄肾的复杂性：对胚胎发生和手术考虑的见解。

Journal of Medicine and Life Pub Date : 2025-01-01 DOI: 10.25122/jml-2024-0325

Ovidiu-Catalin Nechita, Daniel Badescu, Razvan-Ionut Popescu, Stefan Rascu, Razvan-Cosmin Petca, Justin Aurelian, Traian Constantin, Cristian-Valentin Toma, Viorel Jinga, Bogdan Geavlete

{"title":"Reviewing the complexities of horseshoe kidney: insights into embryogenesis and surgical considerations.","authors":"Ovidiu-Catalin Nechita, Daniel Badescu, Razvan-Ionut Popescu, Stefan Rascu, Razvan-Cosmin Petca, Justin Aurelian, Traian Constantin, Cristian-Valentin Toma, Viorel Jinga, Bogdan Geavlete","doi":"10.25122/jml-2024-0325","DOIUrl":"10.25122/jml-2024-0325","url":null,"abstract":"Horseshoe kidney (HSK) is a common renal malformation with unique and complex characteristics. A systematic literature search was conducted using PubMed and ScienceDirect databases. Several theories have been proposed regarding HSK formation, such as the close apposition of the kidneys during ascent through an arterial fork, lateral flexion of the trunk, and caudal embryonic rotation. Emerging evidence from animal models implicates notochord signaling and the sonic hedgehog pathway in HSK formation. The isthmus, a defining feature of HSK, is hypothesized to arise from ectopic mesenchymal tissue. The surgical anatomy of HSK is complex, given the variability in location, orientation, and blood supply. Both arterial and venous anatomy exhibit significant variability, raising questions about whether anomalous blood supply is a cause or a consequence of abnormal renal position. The isthmus usually contains functional renal parenchyma and fusion between the kidneys, primarily at the lower pole. While it is often stated that the inferior mesenteric artery is \"held back\" at the L3 level, this anatomical configuration is present in only 40% of cases. The review highlights the need for further research and provides a comprehensive overview of HSK knowledge.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 1","pages":"10-19"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing the efficacy and safety of bridging therapy vs. monotherapy in patients with minor stroke: a meta-analysis. 比较桥接疗法与单一疗法对轻微中风患者的疗效和安全性：一项荟萃分析。

Journal of Medicine and Life Pub Date : 2025-01-01 DOI: 10.25122/jml-2024-0318

Abdulsalam Aleid, Saud Aldanyowi, Abdulmajeed Aljabr, Sami Almalki, Awn Alessa, Mostafa Alhodibi, Mohammed Alsuwaylih, Yousef Alanazi, Abbas Almutair

{"title":"Comparing the efficacy and safety of bridging therapy vs. monotherapy in patients with minor stroke: a meta-analysis.","authors":"Abdulsalam Aleid, Saud Aldanyowi, Abdulmajeed Aljabr, Sami Almalki, Awn Alessa, Mostafa Alhodibi, Mohammed Alsuwaylih, Yousef Alanazi, Abbas Almutair","doi":"10.25122/jml-2024-0318","DOIUrl":"10.25122/jml-2024-0318","url":null,"abstract":"The two main therapeutic approaches for stroke treatment are endovascular thrombectomy, which involves mechanically removing the thrombus, and bridging therapy, which uses intravenous thrombolytics (IVT) prior to endovascular thrombectomy (EVT). This study aimed to compare monotherapy (EVT or IVT alone) with bridging therapy (IVT+EVT) in terms of efficacy and safety outcomes in patients with minor ischemic stroke. After a thorough screening, eight studies were included for qualitative synthesis and meta-analysis, comprising a total of 3,117 patients across the treatment arms. The main outcomes of interest were the efficacy of treatment modality, the rate of intracerebral hemorrhage (ICH), and mortality. In terms of functional outcomes measured by the Modified Rankin Score (mRs) 0-1, no significant difference was observed when comparing IVT monotherapy with bridging therapy (IVT+EVT), with an odds ratio of 0.79 (P = 0.41). However, IVT was associated with a decreased risk of symptomatic intracranial hemorrhage (sICH) compared to bridging therapy (OR = 0.51; P = 0.02), while EVT was associated with an increased risk of sICH compared to bridging therapy (OR = 8.33; P = 0.01). Mortality rates were comparable between IVT alone compared to bridging therapy and EVT alone compared to bridging therapy (P = 0.14). Although both treatment modalities share similar efficacy, there was a trend in favoring bridging therapy for mortality rates, but it was not statistically significant. Future randomized controlled trials and updated systematic reviews are needed within five to ten years to increase sample sizes and potentially identify statistically significant differences in mortality and other outcomes.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Finite element analysis (FEA) of the stress behavior of some dental materials. 一些牙科材料应力行为的有限元分析。

Journal of Medicine and Life Pub Date : 2025-01-01 DOI: 10.25122/jml-2025-0005

Paolo Di Francesco, Anamaria Bechir, Anca Iuliana Popescu, Manuela Victoria Chivu, Anca Monica Dobrescu, Raluca Monica Comăneanu, Mihail Târcolea

{"title":"Finite element analysis (FEA) of the stress behavior of some dental materials.","authors":"Paolo Di Francesco, Anamaria Bechir, Anca Iuliana Popescu, Manuela Victoria Chivu, Anca Monica Dobrescu, Raluca Monica Comăneanu, Mihail Târcolea","doi":"10.25122/jml-2025-0005","DOIUrl":"10.25122/jml-2025-0005","url":null,"abstract":"This study compared the biomechanical behavior of three widely used dental materials-zirconia, lithium disilicate (IPS e.max CAD), and 3D-printed composite (VarseoSmile CrownPlus)- for maxillary anterior bridge restorations. Finite element analysis (FEA) was employed to evaluate the mechanical response of these materials under normal occlusal forces, replicating real clinical conditions. Key factors analyzed included stress distribution, deformation, and potential for failure under high loads. For each material, material constants such as Poisson's ratio and Young's modulus were used in the simulations, with the values chosen from validated literature sources. The findings demonstrated that zirconia exhibited superior mechanical strength and uniform stress distribution, making it an ideal material for posterior restorations subjected to high biomechanical stresses. Lithium disilicate showed balanced stress distribution and proved to be a versatile material suitable for both anterior and moderate-load restorations, with its superior aesthetic properties making it an attractive option for anterior areas. On the other hand, 3D-printed composite materials were found to have higher stress concentrations, particularly in occlusal regions, and exhibited lower elasticity compared to the other materials, limiting their use in permanent restorations but making them suitable for temporary restorations or areas with lower mechanical demands. This study provides valuable insights into the selection of dental materials for different clinical scenarios, emphasizing the importance of FEA in optimizing material choice and restoration design. The results suggest that while zirconia is ideal for long-term durability, lithium disilicate remains the preferred choice for aesthetic requirements, with 3D-printed composites serving as a promising alternative for long-term temporary applications.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 1","pages":"29-37"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inter-organ correlations in inflammation regulation: a novel biological paradigm in a murine model. 炎症调节中的器官间相关性：小鼠模型中的一种新的生物学范式。

Journal of Medicine and Life Pub Date : 2025-01-01 DOI: 10.25122/jml-2024-0246

Yehudit Shabat, Devorah Rotnemer-Golinkin, Lidya Zolotarov, Yaron Ilan

{"title":"Inter-organ correlations in inflammation regulation: a novel biological paradigm in a murine model.","authors":"Yehudit Shabat, Devorah Rotnemer-Golinkin, Lidya Zolotarov, Yaron Ilan","doi":"10.25122/jml-2024-0246","DOIUrl":"10.25122/jml-2024-0246","url":null,"abstract":"Interactions between immune system constituents are mediated through direct contact or the transfer of mediators. The study aimed to assess the correlation between system components and out-of-body signals in a model of liver inflammation. In the first experiment, mice injected with Concanavalin A (ConA) were housed in a cage with a tube on top containing healthy livers or livers harvested from mice injected with ConA. In the second experiment, mice were housed in a cage with a tube that contained splenocytes harvested from naïve donors or from naïve donors treated in vitro with dexamethasone. Mice were tested for serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels. External whole livers and spleens influenced the immune-mediated inflammatory response of mice. When ConA-injected mice were housed in cages with tubes containing livers harvested from naïve mice, ALT serum levels were significantly reduced. ALT serum levels were significantly elevated when mice were kept in cages with a tube containing livers harvested from ConA-injected mice. In the second part of the experiment, mice injected with ConA and housed in cages with a tube on top that contained splenocytes harvested from naïve donors had increased ALT levels. Similarly, mice with tubes containing splenocytes from dexamethasone-treated naïve donors also showed elevated ALT levels. The data suggest that correlations between immune system constituents can be established using out-of-body whole livers or spleens without contact or transfer of mediators.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 1","pages":"67-72"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of pain intensity after total hip arthroplasty using the Visual Analogue Scale (VAS). 用视觉模拟评分法评估全髋关节置换术后疼痛强度。

Journal of Medicine and Life Pub Date : 2024-12-01 DOI: 10.25122/jml-2024-0362

Madalin Bulzan, Simona Cavalu, Florica Voiță-Mekereș, Călin Tudor Hozan

{"title":"Assessment of pain intensity after total hip arthroplasty using the Visual Analogue Scale (VAS).","authors":"Madalin Bulzan, Simona Cavalu, Florica Voiță-Mekereș, Călin Tudor Hozan","doi":"10.25122/jml-2024-0362","DOIUrl":"10.25122/jml-2024-0362","url":null,"abstract":"This study aimed to assess pain intensity in patients who underwent total hip arthroplasty (THA) using the Visual Analogue Scale (VAS). The study was conducted between 2022 and 2023, enrolling 203 patients admitted to the Orthopedics Department. Participants self-reported their post-surgical pain 24 hours after THA by selecting a VAS rating that best represented their personal experience. Based on their diagnosis, participants were categorized into four relatively homogeneous groups: left-sided coxarthrosis, right-sided coxarthrosis, unilateral THA for bilateral coxarthrosis, and bilateral THA for bilateral coxarthrosis. Data were analyzed using SPSS, with frequency analysis performed using the chi-square (χ2) test. Pain intensity in patients undergoing uncemented THA ranged from mild irritation to pain requiring moderate analgesics. The statistical analysis revealed significant differences in pain frequencies across groups (χ2 (24, 203) = 37.192; P = 0.04), with variations largely attributable to the type of THA performed. VAS scores indicated that patients with unilateral THA for coxarthrosis reported moderate pain lasting up to 30 minutes, necessitating moderate-intensity analgesics. In contrast, participants undergoing bilateral THA experienced more severe pain, requiring the administration of strong analgesics for effective pain relief and increased functionality. Among surgical procedures, uncemented total hip prostheses were associated with the highest frequency of manageable pain, characterized as irritation or mild discomfort requiring moderate analgesics.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 12","pages":"1049-1053"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11771834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Opioid-free anesthesia in enhanced recovery after supratentorial craniotomies: a case series. 无阿片类药物麻醉促进幕上开颅术后恢复：一个病例系列。

Journal of Medicine and Life Pub Date : 2024-12-01 DOI: 10.25122/jml-2024-0280

Irwan Setiadi, Muhammad Rezanda Alifahna, Radian Ahmad Halimi, Dewi Yulianti Bisri

{"title":"Opioid-free anesthesia in enhanced recovery after supratentorial craniotomies: a case series.","authors":"Irwan Setiadi, Muhammad Rezanda Alifahna, Radian Ahmad Halimi, Dewi Yulianti Bisri","doi":"10.25122/jml-2024-0280","DOIUrl":"10.25122/jml-2024-0280","url":null,"abstract":"Enhanced Recovery After Surgery (ERAS) is a recovery method developed to minimize pain and improve post-operative healing in patients. Brain tumor resection using the ERAS concept is relatively new. This case series evaluates the implementation of the ERAS protocol in three female patients diagnosed with supratentorial brain tumors. All patients presented with headache as a primary symptom and underwent craniotomy under general anesthesia supplemented with a scalp block. The surgeries were performed with stable hemodynamics, and anesthesia was maintained using dexmedetomidine, propofol, and rocuronium. After surgery, the patients were immediately extubated and treated in the intensive care unit. The use of opioid-free anesthesia significantly supported the ERAS principles by reducing pain, postoperative nausea and vomiting (PONV), and shivering. This case series highlights the potential of opioid-free anesthesia as an effective alternative to opioids, aligning with the ERAS protocols to improve postoperative outcomes in brain tumor resection.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 12","pages":"1061-1066"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11771829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The dual impact of social media: evolving beauty perceptions and cosmetic procedure practices among patients and providers. 社交媒体的双重影响：患者和提供者之间不断变化的美容观念和美容程序实践。

Journal of Medicine and Life Pub Date : 2024-12-01 DOI: 10.25122/jml-2024-0390

Jumana Hussain Timraz, Rayyan Rafat Samman, Syeda Nafeesa Hashim, Saleha Khan, Maya Faissal Alhomieed, Lara Osama Al Hartany, Laura Mashtoub, Arwa Sindi

{"title":"The dual impact of social media: evolving beauty perceptions and cosmetic procedure practices among patients and providers.","authors":"Jumana Hussain Timraz, Rayyan Rafat Samman, Syeda Nafeesa Hashim, Saleha Khan, Maya Faissal Alhomieed, Lara Osama Al Hartany, Laura Mashtoub, Arwa Sindi","doi":"10.25122/jml-2024-0390","DOIUrl":"10.25122/jml-2024-0390","url":null,"abstract":"Social media is gaining popularity in Saudi Arabia, influencing the concept of beauty and cosmetic surgical needs, particularly among younger individuals. This study aimed to understand how social media is changing the face of cosmetic surgery by reflecting new beauty standards. A comprehensive literature review was conducted, focusing on studies published between 2015 and 2024 from databases such as PubMed and Scopus, examining the impact of social media on decisions related to plastic surgery. Our study accessed multiple studies revealing a concerning trend in the influence of social networks, especially on appearance-related decisions. Some persuasive appeals include false images, celebrity endorsements, and the use of pictures before or after the reconstruction of cosmetic surgery. Additionally, marketing strategies employed by plastic surgeons were found to contribute to the rising demand for both surgical and minimally invasive procedures. This article provides a detailed understanding of how social media can influence ideals and trends in cosmetic surgery while also highlighting the psychological impacts of impossible standards of beauty as well as the ethical implications of advertising practices in the industry. It also examines whether the influence of social media primarily serves the financial interests of providers or adds pressure on them to meet patients' heightened expectations. The limitations in prior research highlight the need for studies involving diverse populations and a closer examination of the potential long-term effects of social media on cosmetic surgery trends and perceptions of beauty.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 12","pages":"1036-1041"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11771832/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143058177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The transformative power of mHealth apps: empowering patients with obesity and diabetes - a narrative review. 移动医疗应用的变革力量：赋予肥胖和糖尿病患者权力——叙述性回顾。

Journal of Medicine and Life Pub Date : 2024-12-01 DOI: 10.25122/jml-2024-0340

Alina Spinean, Simona Carniciu, Oana Alexandra Mladin, Cristian Serafinceanu

{"title":"The transformative power of mHealth apps: empowering patients with obesity and diabetes - a narrative review.","authors":"Alina Spinean, Simona Carniciu, Oana Alexandra Mladin, Cristian Serafinceanu","doi":"10.25122/jml-2024-0340","DOIUrl":"10.25122/jml-2024-0340","url":null,"abstract":"The rising prevalence of obesity and diabetes underscores the need for innovative approaches to promote healthier lifestyles and improve clinical outcomes. Emerging evidence suggests that integrating mobile health (mHealth) technologies, such as smartphone applications and wearable devices, may provide a promising solution. mHealth interventions have the potential to enhance the delivery and accessibility of nutritional therapy and lifestyle modification programs for people with obesity and diabetes. This systematic review examines the available literature on the application and effectiveness of mHealth-based tools and technologies in managing these chronic conditions, offering insights into the current state of the field and opportunities for future research and clinical implementation. The review explores the diverse range of mHealth apps and devices utilized, their impact on weight loss, glycemic control, and other health-related outcomes, and the challenges and limitations associated with their use. This study highlights future directions and the growing importance of mHealth in the comprehensive management of obesity and diabetes to inform healthcare professionals, researchers, and policymakers about the potential of these innovative approaches to enhance patient care and improve population health.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 12","pages":"1030-1035"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11771836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physiological effects of hand grip and cold pressor tests in young Saudi adults. 握力和冷压试验对沙特青年的生理影响。

Journal of Medicine and Life Pub Date : 2024-12-01 DOI: 10.25122/jml-2024-0378

Raju Suresh Kumar, Abdulaziz Abdullah Alqarni, Musaad Jamaan Alghamdi, Saad Amer Alharbi, Omar Loutfi Alsharef, Mohamed Eldigire Ahmed

{"title":"Physiological effects of hand grip and cold pressor tests in young Saudi adults.","authors":"Raju Suresh Kumar, Abdulaziz Abdullah Alqarni, Musaad Jamaan Alghamdi, Saad Amer Alharbi, Omar Loutfi Alsharef, Mohamed Eldigire Ahmed","doi":"10.25122/jml-2024-0378","DOIUrl":"10.25122/jml-2024-0378","url":null,"abstract":"The risk of cardiovascular disease differs among various ethnic groups, highlighting disparities in cardiovascular health among different populations. While multiple studies from other countries have looked at changes in physiological parameters during autonomic function tests like isometric handgrip and cold pressor tests, no correlational research has been done in Saudi Arabia. This lacuna underscores the importance of examining the relationship between cardiorespiratory parameters in young Saudi Arabian individuals during these tests. This study aimed to determine the correlation between the isometric handgrip and cold pressor tests and physiological parameters in healthy young Saudi Arabian college students. A single-arm interventional study was conducted with a cohort of 65 healthy young adult Saudi college students, including male and female participants. A point estimate was calculated with a 95% confidence level. Physiological parameters were analyzed and compared at rest and during isometric handgrip and cold pressor tests. The study involved participants with an average age of 21.12 ± 1.02, predominantly male students. A significant impact was observed only in respiratory rate (P = 0.007) during the isometric handgrip and cold pressor tests. In contrast, blood pressure parameters and arterial oxygen saturation values showed no statistical significance during both tests. This sheds light on their autonomic responses to physiological stressors and contributes to our understanding of cardiovascular health across diverse populations, guiding future interventions for global improvements in cardiorespiratory outcomes.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 12","pages":"1067-1071"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11771833/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0