Journal of Medicine and Life最新文献_第10页

Appropriate incorporation of susceptibility-weighted magnetic resonance imaging into routine imaging protocols for accurate diagnosis of traumatic brain injuries: a systematic review. 将易感加权磁共振成像适当纳入常规成像方案以准确诊断脑外伤：系统性综述。

Journal of Medicine and Life Pub Date : 2024-03-01 DOI: 10.25122/jml-2023-0487

Osama Jaafari, Suliman Salih, Ajnas Alkatheeri, Muhamed Alshehri, Majedh Al-Shammari, Mousa Maeni, Abdullah Alqahtani, Wijdan Alomaim, Mohamed Hasaneen

{"title":"Appropriate incorporation of susceptibility-weighted magnetic resonance imaging into routine imaging protocols for accurate diagnosis of traumatic brain injuries: a systematic review.","authors":"Osama Jaafari, Suliman Salih, Ajnas Alkatheeri, Muhamed Alshehri, Majedh Al-Shammari, Mousa Maeni, Abdullah Alqahtani, Wijdan Alomaim, Mohamed Hasaneen","doi":"10.25122/jml-2023-0487","DOIUrl":"10.25122/jml-2023-0487","url":null,"abstract":"Traumatic brain injury (TBI) results from physical or traumatic injuries to the brain's surrounding bony structures and associated tissues, which can lead to various sequelae, including simple concussion, acute epidural hematoma, parenchymal contusions, subarachnoid hemorrhage, diffuse axonal injury, and chronic traumatic encephalopathy. Susceptibility-weighted imaging (SWI) has enhanced the accuracy of neuroimaging for these injuries. SWI is based on 3D gradient echo magnetic resonance imaging (MRI) with long echo times and flow compensation. Owing to its sensitivity to deoxyhemoglobin, hemosiderin, iron, and calcium, SWI is extremely informative and superior to conventional MRI for the diagnosis and follow-up of patients with acute, subacute, and prolonged hemorrhage. This systematic review aimed to evaluate and summarize the published articles that report SWI results for the evaluation of TBI and to determine correlations between clinical status and SWI results. Consequently, our analysis also aimed to identify the appropriate MRI sequences to use in the assessment of patients with TBI. We searched the Medline and Embase online electronic databases for relevant papers published from 2012 onwards. We found that SWI had higher sensitivity than gradient echo MRI in detecting and characterizing microbleeds in TBIs and was able to differentiate diamagnetic calcifications from paramagnetic microhemorrhages. However, it is important that future research not only continues to evaluate the utility of SWI in TBIs but also attempts to overcome the limitations of the studies described in this review, which should help validate the conclusions and recommendations from our analysis.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 3","pages":"273-280"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141751910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of COVID-19 on asthma control in Kirkuk City: an analysis of post-pandemic trends. COVID-19 对基尔库克市哮喘控制的影响：大流行后趋势分析。

Journal of Medicine and Life Pub Date : 2024-03-01 DOI: 10.25122/jml-2023-0175

Bilal Jamal Kamal, Mohammed Ali Khalaf

引用次数: 0

Blink rate during saccadic eye movements: insights from patients with chronic pain. 眼球移动过程中的眨眼率：慢性疼痛患者的启示。

Journal of Medicine and Life Pub Date : 2024-03-01 DOI: 10.25122/jml-2024-0271

Emanuel Ştefănescu, Ştefan Strilciuc, Vlad-Florin Chelaru, Diana Chira, Dafin Mureşanu

{"title":"Blink rate during saccadic eye movements: insights from patients with chronic pain.","authors":"Emanuel Ştefănescu, Ştefan Strilciuc, Vlad-Florin Chelaru, Diana Chira, Dafin Mureşanu","doi":"10.25122/jml-2024-0271","DOIUrl":"10.25122/jml-2024-0271","url":null,"abstract":"Chronic pain (CP) significantly impacts quality of life and poses an increasing economic burden on healthcare systems worldwide. This study investigates the relationship between blink rate during saccadic eye movements and pain perception in patients with CP. Ninety-two patients with CP (24 men, 68 women) were assessed using eye-tracking technology during horizontal and vertical saccadic tasks. Pain perception was evaluated using the Central Sensitization Inventory - Part A and the McGill Pain Questionnaire, and anxiety levels were measured using the State-Trait Anxiety Inventory. The results revealed a significant correlation between blink rates in horizontal and vertical tasks (ρ = 0.668, P < 0.001). However, there was no correlation between blink rate and age, pain perception, or anxiety scores. Conversely, measures of pain perception were positively correlated with each other and with anxiety scores. These findings suggest that while blink rate may reflect oculomotor function, it is not directly influenced by pain perception or anxiety in patients with CP. The present study highlights the potential of eye tracking for the comprehensive assessment and management of patients with CP.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 3","pages":"368-374"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262601/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141753810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

QEEG indices in traumatic brain injury - insights from the CAPTAIN RTMS trial. 创伤性脑损伤的 QEEG 指数--CAPTAIN RTMS 试验的启示。

Journal of Medicine and Life Pub Date : 2024-03-01 DOI: 10.25122/jml-2024-0187

Verişezan Roşu Olivia, Diana Chira, Vlad-Florin Chelaru, Chertic Dăbală Diana, Livinț Popa Livia, Ana-Maria Buruiană, Fior Dafin Mureşanu

引用次数: 0

Reproductive outcome after in vitro fertilization in endometriosis - key factors and implications. 子宫内膜异位症患者体外受精后的生殖结果--关键因素和影响。

Journal of Medicine and Life Pub Date : 2024-03-01 DOI: 10.25122/jml-2024-0114

Elena-Silvia Nadă, Ciprian Andrei Coroleucă, Cătălin Bogdan Coroleucă, Elvira Brătilă

{"title":"Reproductive outcome after in vitro fertilization in endometriosis - key factors and implications.","authors":"Elena-Silvia Nadă, Ciprian Andrei Coroleucă, Cătălin Bogdan Coroleucă, Elvira Brătilă","doi":"10.25122/jml-2024-0114","DOIUrl":"10.25122/jml-2024-0114","url":null,"abstract":"Endometriosis is a benign chronic disease with a major impact on a woman's quality of life, mainly due to painful physical symptoms. Endometriosis is also a common cause of infertility caused by low ovarian reserve, distorted pelvic anatomy, and severe local inflammation with a direct negative impact on the quality of oocytes, embryos, and endometrium. We conducted a retrospective study between January 2019 and December 2023, including women with a history of surgery for endometriosis who underwent in vitro fertilization (IVF) to achieve pregnancy. Their reproductive outcome was compared with a group of patients with documented tubal obstruction. The aim of our study was to identify the factors associated with a positive impact on the pregnancy rate, specifically age, anti-Mullerian hormone (AMH), ovarian stimulation protocol, and types of gonadotropins used. We analyzed a group of 175 patients with endometriosis compared with 189 patients with tubal obstruction. The average age was similar between the two groups but with a difference in the average AMH value (1.63 ± 1.09 ng/mL vs. 2.55 ± 1.67 ng/mL). The most utilized ovarian stimulation protocol in both groups was the short gonadotropin-releasing hormone (GnRH) antagonist. The clinical pregnancy rate was 27.2% in the endometriosis group and 54.7% in the tubal obstruction group. Our study revealed that treatment with corifollitropin alfa in the endometriosis group was associated with a higher clinical pregnancy rate. AMH and age proved to be significant independent factors for the reproductive outcome.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 3","pages":"334-340"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262606/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141751918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of oral insulin nanoparticles for the management of hyperglycemia in a rat model of diabetes induced with streptozotocin. 口服胰岛素纳米颗粒在链脲佐菌素诱导的糖尿病大鼠模型中控制高血糖的疗效。

Journal of Medicine and Life Pub Date : 2024-02-01 DOI: 10.25122/jml-2023-0355

Ghasak Kais Abd-Alhussain, Mohammed Qasim Yahya Mal-Allah Alatrakji, Shayma'a Jamal Ahmed, Hayder Adnan Fawzi

{"title":"Efficacy of oral insulin nanoparticles for the management of hyperglycemia in a rat model of diabetes induced with streptozotocin.","authors":"Ghasak Kais Abd-Alhussain, Mohammed Qasim Yahya Mal-Allah Alatrakji, Shayma'a Jamal Ahmed, Hayder Adnan Fawzi","doi":"10.25122/jml-2023-0355","DOIUrl":"10.25122/jml-2023-0355","url":null,"abstract":"Insulin is the cornerstone of treatment in type 1 diabetes mellitus. However, because of its protein structure, insulin has to be administered via injection, and many attempts have been made to create oral formulations, especially using nanoparticles (NPs). The aim of this study was to compare the hypoglycemic effect of insulin-loaded NPs to that of subcutaneous insulin in an in vivo rat model of diabetes. We used biodegradable D-α-tocopherol polyethylene glycol succinate-emulsified, chitosan-capped poly(lactic-co-glycolic acid) NPs loaded with soluble human insulin in a dose of 20 IU/kg body weight, and examined the physical characteristics of NPs in vivo and in vitro. Serum glucose levels were reduced after 6 h, but the difference was not significant compared to subcutaneous insulin; at 12 h and 24 h, insulin levels were significantly higher in rats treated with NPs than in rats treated with subcutaneous insulin. There was no significant difference in serum insulin levels at 12 h and 24 h compared to non-diabetic rats. Our findings suggest that chitosan-based NPs are able to maintain good glycemic control for up to 24 h and can be considered a potential carrier for oral insulin delivery.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 2","pages":"217-225"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11131628/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141174667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A positive effect of Cerebrolysin on motor functions and spasticity in ALS with limb or bulbar onset is questionable. 脑复康对肢端或球部发病的渐冻症患者的运动功能和痉挛是否有积极作用值得怀疑。

Journal of Medicine and Life Pub Date : 2024-02-01 DOI: 10.25122/jml-2024-0158

Josef Finsterer

引用次数: 0

FUE as the first surgical option for hair reconstruction on scalp and facial skin grafts - case report. FUE 作为头皮和面部皮肤移植毛发重建的首选手术方案 - 病例报告。

Journal of Medicine and Life Pub Date : 2024-02-01 DOI: 10.25122/jml-2023-0492

Felix Mircea Popescu, Lidia Filip, Matei Popescu

{"title":"FUE as the first surgical option for hair reconstruction on scalp and facial skin grafts - case report.","authors":"Felix Mircea Popescu, Lidia Filip, Matei Popescu","doi":"10.25122/jml-2023-0492","DOIUrl":"10.25122/jml-2023-0492","url":null,"abstract":"Post-combustion alopecia presents a complex medical challenge with implications spanning dermatological and psychiatric disorders. The use of hair transplantation has proven to be a significant improvement for this condition. However, the current management involves various techniques, each with advantages and disadvantages. Progressive skin expansions, surgical scar reduction, and skin grafts containing hair follicles yield unsatisfactory aesthetic outcomes and have limited applicability as a first-line treatment for fire victims. So far, follicular unit extraction (FUE) has proven to be one of the most versatile procedures in such cases, having the potential to restore a natural anatomical profile closely resembling the pre-traumatic appearance that led to the traumatic alopecia. Additionally, it contributes to the improvement of associated psychiatric comorbidities, facilitating proper social reintegration and enhancing overall quality of life. This report focuses on a case of post-combustion alopecia and severe facial distortion due to third-degree burns resulting in severe psychiatric comorbidities, which benefited from a proper social reintegration and improvement of the quality of life after three consecutive sessions of FUE for scalp and eyebrow hair.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 2","pages":"233-235"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11131638/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141174760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasound accuracy in evaluating renal calculi in Maysan province. 梅桑省肾结石超声评估的准确性。

Journal of Medicine and Life Pub Date : 2024-02-01 DOI: 10.25122/jml-2023-0477

Saud Kadhim Abbas, Thaer Saleh Sabor Al-Omary, Hayder Adnan Fawzi

{"title":"Ultrasound accuracy in evaluating renal calculi in Maysan province.","authors":"Saud Kadhim Abbas, Thaer Saleh Sabor Al-Omary, Hayder Adnan Fawzi","doi":"10.25122/jml-2023-0477","DOIUrl":"10.25122/jml-2023-0477","url":null,"abstract":"Renal calculi are a common clinical presentation. While ultrasound (US) is a widely used imaging modality for kidney stone diagnosis due to its accessibility and lower cost, its accuracy compared to computerized tomography (CT), the gold standard, remains understudied. This cross-sectional study evaluated the diagnostic accuracy of ultrasound for detecting and characterizing kidney stones compared to computed tomography (CT). Fifty-six patients with suspected kidney stones based on flank pain underwent abdominal ultrasound to assess stone presence, size, location, and the severity of any hydronephrosis (kidney swelling). These findings were then confirmed with a subsequent non-contrast CT scan. There was a fair agreement between US and CT (Kappa = 0.368) for detecting the stone location. The US could not detect 7 (12.5%) stones, being less sensitive in the middle and upper calyx compared to CT. There was a fair agreement between the US and CT (Kappa = 0.394) for detecting the severity of hydronephrosis. The US was less sensitive to moderate and severe hydronephrosis compared to CT. The abdominal ultrasound demonstrated excellent reliability for stone size measurement (intraclass correlation = 0.924), with CT measurements only slightly larger on average (mean difference 0.9 mm). Although abdominal ultrasound provides reliable stone size assessment, its capacity to accurately localize stones and assess hydronephrosis severity is limited.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 2","pages":"226-232"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11131636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141175190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determinants of child stunting in the dryland area of East Nusa Tenggara Province, Indonesia: insights from a national-level survey. 印度尼西亚东努沙登加拉省干旱地区儿童发育迟缓的决定因素：一项全国性调查的启示。

Journal of Medicine and Life Pub Date : 2024-02-01 DOI: 10.25122/jml-2023-0313

Intje Picauly, Anak Agung Ayu Mirah Adi, Eflita Meiyetriani, Majematang Mading, Pius Weraman, Siti Fadhilatun Nashriyah, Daniela Leonor Adeline Boeky, Varry Lobo, Asmulyati Saleh, Jane Austen Peni, Ahmad Thohir Hidayat, Marni Marni

{"title":"Determinants of child stunting in the dryland area of East Nusa Tenggara Province, Indonesia: insights from a national-level survey.","authors":"Intje Picauly, Anak Agung Ayu Mirah Adi, Eflita Meiyetriani, Majematang Mading, Pius Weraman, Siti Fadhilatun Nashriyah, Daniela Leonor Adeline Boeky, Varry Lobo, Asmulyati Saleh, Jane Austen Peni, Ahmad Thohir Hidayat, Marni Marni","doi":"10.25122/jml-2023-0313","DOIUrl":"10.25122/jml-2023-0313","url":null,"abstract":"Stunting remains a critical public health issue in Indonesia, particularly in the province of East Nusa Tenggara. This region, characterized by its archipelagic dryland geography, has reported the highest prevalence of stunting among children under five from 2007 to 2021. The study aimed to examine the relationship between various characteristics of children under five and household factors with the occurrence of stunting. This observational study, with a cross-sectional design, used secondary data from the 2021 Indonesian Nutrition Status Survey, covering 7,835 children under five. We analyzed the data to identify patterns and relationships, using univariate analysis to display percentage distributions and bivariate analysis through multiple binary logistic regression tests. The results of the multiple logistic regression test showed that indicators of family characteristics such as age, gender, low birth weight, body length, possession of birth certificates, and receiving complementary feeding were all related to stunting. Additionally, household factors such as toilet type, National Health Insurance coverage, ownership of a Prosperous Family Card, and residential area were significant determinants. Factors contributing to stunting in dryland areas include a range of elements from both family characteristics-such as age, gender, birth certification, low birth weight, and initial body length, to the introduction of supplementary feeding-and household indicators, including the use of specific types of latrines (Plengsengan and Cemplung types without covers), health insurance coverage, possession of Prosperous Family Cards, and the family's residential area.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"17 2","pages":"147-156"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11131646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141174708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0