Journal of Multidisciplinary Healthcare最新文献

{"title":"Understanding Colorectal Cancer Screening Barriers in Saudi Arabia: Insights From a Cross-Sectional Study.","authors":"Noura S Alhassan, Mohammed Basem Beyari, Saleh Husam Aldeligan, Abdulaziz Abdulmuhsin Alqusiyer, Shatha Abdulaziz Almutib, Mohammed Ahmed Alarfaj, Maha Hamadien Abdulla, Thamer Bin Traiki","doi":"10.2147/JMDH.S507481","DOIUrl":"10.2147/JMDH.S507481","url":null,"abstract":"<p><strong>Introduction: </strong>Colorectal cancer is a significant health concern in Saudi Arabia, ranking among the most common cancers and often presenting at advanced stages due to low early detection rates. Despite available screening tools, many cases are diagnosed late, leading to poor outcomes. The importance of early detection through screening cannot be overstated as it significantly improves prognosis and reduces mortality.</p><p><strong>Methods: </strong>This study was conducted as a cross-sectional survey in Riyadh from January to July 2024. It aimed to assess awareness and barriers to colorectal cancer screening among the general public. A self-administered questionnaire was distributed, yielding 768 eligible responses after applying exclusion criteria.</p><p><strong>Results: </strong>The results revealed that, while 88% of respondents were aware of colorectal cancer, only 16% had undergone screening tests primarily via colonoscopy. Significant barriers to screening included a lack of physician recommendation, absence of a comprehensive national screening program and fear of complications from colonoscopy. Females were more likely to experience embarrassment and fair of pain as barriers compared to males. Additionally, residents of rural areas faced challenges related to the avalanche of screening facilities.</p><p><strong>Conclusion: </strong>These findings underscore the need for targeted public health interventions, including enhanced awareness campaigns and the development of a national CRC screening program to increase early detection rates and reduce the burden of colorectal cancer in Saudi Arabia.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"1335-1344"},"PeriodicalIF":2.7,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11890475/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Bibliometric Analysis of the Application of Brain-Computer Interface in Rehabilitation Medicine Over the Past 20 Years.","authors":"Jinghui Huang, Lele Huang, Ying Li, Fanfu Fang","doi":"10.2147/JMDH.S509747","DOIUrl":"10.2147/JMDH.S509747","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to conduct a bibliometric analysis of the application of brain- computer interface (BCI) in rehabilitation medicine, assessing the current state, developmental trends, and future potential of this field. By systematically analyzing relevant literature, we seek to identify key research themes and enhance understanding of BCI technology in rehabilitation.</p><p><strong>Methods: </strong>We utilized bibliometric analysis tools such as VOSviewer and CiteSpace to screen and analyze 426 relevant articles from the Web of Science Core Collection (WoSCC) database. We quantitatively evaluated citation patterns, publication trends, and the collaboration networks of research institutions and authors to uncover research hotspots and frontier dynamics in the field.</p><p><strong>Results: </strong>The findings indicate a continuous increase in research publications since 2003, with a notable peak occurring between 2019 and 2021. The analysis revealed that motor imagery, motor recovery, and signal processing are the predominant research themes. Furthermore, the United States and China are leading in the publication volume related to BCI and rehabilitation medicine. Key research institutions include the University of Tübingen and the New York State Department of Health, with significant contributions from scholars like Niels Birbaumer.</p><p><strong>Conclusion: </strong>Although the current research on BCI in rehabilitation medicine shows significant potential and efficacy, further exploration of certain research directions is needed, along with the promotion of interdisciplinary collaboration to comprehensively address complex real-world issues such as motor function impairment. Future research should focus on optimizing training models, enhancing technical feasibility, and exploring home rehabilitation applications to facilitate the broader adoption of BCI technology in rehabilitation medicine.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"1297-1317"},"PeriodicalIF":2.7,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11890000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of COVID-19 on Dental Clinic Transmission: Leveraging Internet of Things Technology.","authors":"Banu Uygun-Can, Parla Meva Durmazpınar, Şirin Hatipoğlu, Bilge Acar-Bolat, Çağla Özen, Hesna Sazak-Öveçoğlu, Tanju Kadir","doi":"10.2147/JMDH.S499841","DOIUrl":"10.2147/JMDH.S499841","url":null,"abstract":"<p><strong>Background: </strong>This study focused on the risk posed by pre-symptomatic and asymptomatic carriers in dental clinics during the period (February-June 2022) when Covid-19 transmission was highest and aimed to investigate the effectiveness of infection control protocols in the prevention of SARS-CoV-2 transmission. It also evaluated the potential of wearable sensors as part of the Internet of Things (IoT) to prevent cross-infection.</p><p><strong>Material and methods: </strong>Swab samples were collected from surfaces and air filters in dental clinics and analyzed using RT-PCR both before and after disinfection processes. Clinicians also used IoT-enabled wearable sensors and completed surveys (n=100) evaluating the impact of these technologies on infection control practices. The sensors monitored clinicians' movements and patient interactions to assess cross-infection risks.</p><p><strong>Results: </strong>All RT-PCR tests returned negative results, indicating that no SARS-CoV-2 was detected on the sampled surfaces or air filters. Surveys revealed that 70% of resident clinicians trusted the effectiveness of wearable sensors in infection control. The technology was particularly well received among younger clinicians and was found to be effective in strengthening contact tracing, control measures, and awareness.</p><p><strong>Conclusion: </strong>Strict infection control measures have contributed to preventing Covid-19 infections in dental clinics, although asymptomatic cases may still be present. These findings highlight the importance of adopting advanced technologies such as wearable sensors to support current infection control measures. With further studies, the scalability and integration of IoT technologies into routine infection control practices in diverse healthcare settings can be better understood, enhancing infection control potential and significantly contributing to the safety of healthcare workers and patients.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"1319-1334"},"PeriodicalIF":2.7,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11889996/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mapping the Knowledge Landscape of and Emerging Future Trends in Stem Cell Therapy for Osteoarthritis: A Bibliometric Analysis of the Literature From 1998 to 2024.","authors":"Zhishou Meng, Dongqin He, Honggang Wang, Lijuan Ma, Le Guan, Yongning Ai, Jianxin Yang, Ruxing Liu","doi":"10.2147/JMDH.S508807","DOIUrl":"10.2147/JMDH.S508807","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this study was to conduct a bibliometric analysis of the literature on stem cell therapy for osteoarthritis (OA) to visualize recent developments, identify hot spots, and determine trends in the field.</p><p><strong>Background: </strong>OA is a chronic disease that affects the joints and their surrounding tissues, leading to progressive damage to the articular cartilage and ultimately to the subchondral bone and the surrounding synovial structures. OA is a disabling disease with an increasing incidence and prevalence in the general population. Modulation of immunity and inflammation and improvement of cell survival and differentiation through multidirectional differentiation of stem cells is a potential strategy for the treatment of OA.</p><p><strong>Methods: </strong>We searched for publications on \"stem cell therapy for osteoarthritis\" in the Web of Science (WOS) core collection database from 1998-2024 and summarized the results, including year of publication, country, institution, author, and collaborative network generated using VOSviewer and Citespace. In addition, research trends were identified. Finally, we summarized the hot topics and identified future research trends.</p><p><strong>Results: </strong>This study ultimately included 2341 valid papers, with a trend toward a gradual increase in the number of publications over time. The country, institution, author, and journal with the highest number of publications and citations were China, the University of California system, Sekiya I, and Osteoarthritis and Cartilage, respectively. High-frequency keyword clusters included cell therapy, stem cells, tissue engineering, and extracellular vesicles.</p><p><strong>Conclusion: </strong>Through visualization and analysis, we elucidated the trends and research hotspots in the field over the past five years. The analysis revealed that stem cell transplantation and exosome therapy for OA may be the focus of future research. This study lays the foundation for future research and clinical work on stem cell therapy in this field.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"1281-1295"},"PeriodicalIF":2.7,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11890084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Healthcare Personnel Experiences With Health Literacy Sensitivity in Relation to Work Satisfaction and Stress: A Qualitative Study.","authors":"Malene Nerbøvik Stavdal, Marie Hamilton Larsen, Astrid Klopstad Wahl, Ingeborg Strømseng Sjetne, Anners Lerdal, Caryl L Gay, Christine Råheim Borge","doi":"10.2147/JMDH.S493548","DOIUrl":"10.2147/JMDH.S493548","url":null,"abstract":"<p><strong>Objective: </strong>To qualitatively explore healthcare personnel's (HCP) experiences with health literacy sensitivity in relation to work satisfaction and stress. Being HL sensitive means that HCP have adequate knowledge, skills, and attitudes to follow up on patients' HL needs.</p><p><strong>Methods: </strong>Four focus group interviews were conducted with 30 hCP from a medium-sized general hospital in Oslo, Norway. We used inductive thematic analysis developed by Braun & Clark. NVivo v12 software assisted data analysis.</p><p><strong>Results: </strong>Three main themes were identified: (1) HCP experiences with HL (2) HCP experience barriers with HL sensitivity, and (3) HCP collaboration and communication are essential for HL. Variability in HL understanding among HCP may lead to challenges in providing patient-centered care. Factors such as heavy workloads, cultural barriers, and organizational limitations hinder HL sensitivity and can cause frustration and stress among HCP.</p><p><strong>Conclusion: </strong>Targeted interventions and organizational support are essential to address HCP's obstacles with HL sensitivity. Utilizing improved communication techniques and HL tools may help reduce stress and frustration.</p><p><strong>Practice implications: </strong>To optimize HL sensitivity, it is imperative to prioritize HCP needs. Organizations should strive to facilitate HL in a way that does not impose additional stress on HCP.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"1269-1280"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881602/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive Analysis of the Biomechanical Research of Pelvic Organ Prolapse: A Scientometric Approach.","authors":"Haolan Du, Miyang Yang, Xuge Qi, Lanlan Yang, Zhaochu Wang, Tao Yang, Shangwen Xu, Liyuan Fu","doi":"10.2147/JMDH.S473196","DOIUrl":"10.2147/JMDH.S473196","url":null,"abstract":"<p><strong>Background: </strong>Pelvic organ prolapse (POP) has become a significant public health issue, with its prevalence increasing proportionally with age. Despite the considerable number of biomechanical studies reported on POP, there remains a lack of a systematic approach to summarize and synthesize all existing research.</p><p><strong>Methods: </strong>The Web of Science Core Collection (WoSCC) database was used as the data source to select literature published from 2003 to 2023 related to biomechanical research of POP. We employed various visualization software to generate scientific knowledge maps, facilitating data analysis and visual representation.</p><p><strong>Results: </strong>This study included 292 publications, comprising 252 research articles (86.3%) and 40 review articles (13.7%). The United States has emerged as a leading nation in terms of productivity, with the University of Porto making significant contributions. Robust partnerships are maintained by all countries and institutions involved. Moali PA stands out as the most prolific author, while Deprest J exhibits exemplary levels of collaboration. Notably, the journal <i>Int Urogynecol J</i> has the highest publication rate and citation frequency, making a significant contribution and demonstrating considerable academic influence in the field. Keyword and cluster analysis reveal that key research areas include validating finite element (FE) models of pelvic floor structures, studying interactions among pelvic support systems, evaluating the impact of vaginal delivery, assessing the effects of various mesh or 3D-printed materials on POP repair, remodeling vaginal connective tissue in POP patients, and biomechanical performance evaluations of pelvic floor tissues. Future research will likely focus on the development of personalized and regenerative treatment strategies. Moreover, advancements in machine learning, various regenerative medicine approaches, and multimodal large-scale FE modeling offer promising insights for development.</p><p><strong>Conclusion: </strong>This study presents a comprehensive analysis of the knowledge system and research directions of the biomechanics of POP, providing valuable guidance for future research endeavors.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"1249-1268"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is High-Intensity Interval Training an Option for Post-Kidney Transplant Physical Rehabilitation Programmes? A Scoping Review.","authors":"Viviane Lovatto, Bruna da Silva Sousa, Vera Regina Fernandes da Silva Marães","doi":"10.2147/JMDH.S491605","DOIUrl":"10.2147/JMDH.S491605","url":null,"abstract":"<p><strong>Purpose: </strong>To systematically and broadly review the literature to show the available information on high-intensity interval training for kidney transplant recipients as an adjunct to physical rehabilitation.</p><p><strong>Methods: </strong>A scoping review of high-intensity interval training for post-kidney transplant patients was conducted by searching the PubMed, EMBASE (Elsevier), Scopus (Elsevier), Web of Science, and PEDro databases. Full-text records on the subject were included. Articles not published in English were excluded. The selected articles went through careful production quality analysis using the PEDro scale.</p><p><strong>Results: </strong>The search identified 26 articles, 3 of which met the inclusion criteria. The material demonstrated satisfaction, confidence, improvement in resting heart rate, and absence of adverse effects from high-intensity interval training for kidney transplant recipients.</p><p><strong>Conclusion: </strong>Based on this scoping review, high-intensity interval training for kidney transplant patients may be beneficial for physical and mental aspects and complement physical rehabilitation programmes, but there is a need for more studies with robust samples and long-term follow-up to confirm these benefits.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"1231-1239"},"PeriodicalIF":2.7,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11878123/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Neurodevelopmental Outcomes in Children With Congenital Heart Disease Using Magnetic Resonance Imaging (MRI): Focus on Brain Volume as a Predictor of Neurodevelopmental Abnormalities.","authors":"Ming-Cui Fu, Ye Lin, Feng Yang, Ying Wang, Xu-Ming Mo","doi":"10.2147/JMDH.S508533","DOIUrl":"10.2147/JMDH.S508533","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to evaluate the neurodevelopmental outcomes in children with congenital heart disease (CHD) using magnetic resonance imaging (MRI), and to assess the role of brain volume metrics as predictors of neurodevelopmental abnormalities.</p><p><strong>Methods: </strong>In this retrospective cohort study, 160 children with CHD treated at Children's Hospital of Nanjing Medical University from January 2020 to December 2023 were analyzed. Patients were classified into normal (DQ ≥ 70, n=106) and abnormal neurodevelopment (DQ < 70, n=54) groups based on Developmental Quotient (DQ) scores. MRI scans were used to measure total brain volume, cortical gray matter, deep gray matter, white matter, and cerebrospinal fluid volumes. Neurodevelopmental assessments focused on adaptive behavior, motor skills, language, and personal-social behavior. ROC analysis was performed to determine the predictive value of brain volume metrics for neurodevelopmental abnormalities.</p><p><strong>Results: </strong>Total brain volume in the normal group (341.82 ± 10.43 mL) was significantly higher than in the abnormal group (323.92 ± 10.24 mL) (P < 0.05). Cortical gray matter volume in the normal group (131.47 ± 4.02 mL) was also significantly greater than in the abnormal group (121.63 ± 6.91 mL) (P < 0.05). No significant differences were observed in white matter, deep gray matter, or cerebrospinal fluid volumes. Children in the abnormal group scored significantly lower in all developmental domains (P < 0.05). ROC analysis showed that total brain volume (AUC = 0.968) and cortical gray matter volume (AUC = 0.936) were strong predictors of neurodevelopmental abnormalities (P < 0.001).</p><p><strong>Conclusion: </strong>Total brain volume and cortical gray matter volume, as measured by MRI, are effective predictors of neurodevelopmental abnormalities in children with CHD and can serve as valuable tools for early neurodevelopmental assessment.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"1241-1248"},"PeriodicalIF":2.7,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive Needs Assessment for Enhancing Self-Management in People with Lipoedema and the Support Provided by Their Healthcare Professionals.","authors":"Lise Maren Kloosterman, Harriët Jager-Wittenaar, Francine Schneider, Ad Hendrickx, Rienk Dekker, Aldo Scafoglieri","doi":"10.2147/JMDH.S508816","DOIUrl":"10.2147/JMDH.S508816","url":null,"abstract":"<p><strong>Background: </strong>The cause of lipoedema remains unclear, and the condition is currently incurable. Effective self-management is therefore essential for coping with its physical and psychological impacts and the necessary lifestyle adjustments. This study aimed to assess the needs, barriers, and facilitators for enhancing self-management and self-management support from the perspectives of people with lipoedema and the healthcare professionals (HCPs) involved in their care.</p><p><strong>Methods: </strong>The study used a mixed-methods approach, incorporating a narrative review focused on people with chronic conditions and their HCPs, along with focus groups involving people diagnosed with lipoedema and the HCPs involved in their care. The Core Processes of the Intervention Mapping method guided a systematic approach to address the study's objectives. Qualitative data were analyzed using a grounded theory approach.</p><p><strong>Results: </strong>Findings revealed unique self-management barriers for people with lipoedema, including limited awareness and expertise among HCPs, as well as stigmatization from both HCPs and society. Participants identified a need for tailored lifestyle plans, guidance, and support for monitoring progress. Key facilitators included self-management skills, supportive networks, and role models. HCPs noted barriers in communication and collaboration due to a lack of specialized professionals and negative attitudes toward lipoedema. They expressed a need for multidisciplinary/interprofessional teams, accurate diagnosis, patient openness, and reliable information resources. Facilitators included fostering trust, encouraging patient participation, and setting achievable goals.</p><p><strong>Conclusion: </strong>This study underscores the need for tailored self-management interventions for people with lipoedema. The adaptation of existing self-management strategies from other chronic conditions should take into account the specific needs, barriers, and facilitators of people with lipoedema and their HCPs.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"1217-1230"},"PeriodicalIF":2.7,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874744/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conjunct Effects of Transcranial Direct Current Stimulation with Mirror Therapy on Motor Control and Muscle Performance in Spastic Quadriplegic Cerebral Palsy Children: A Randomized Clinical Trial.","authors":"Shoaib Waqas, Ashfaq Ahmad, Juliana Barbosa Goulardins, Zainab Hassan, Asif Hanif, Muhammad Tariq","doi":"10.2147/JMDH.S506784","DOIUrl":"10.2147/JMDH.S506784","url":null,"abstract":"<p><strong>Background: </strong>Cerebral palsy (CP) is a birth-related non-progressive neuromotor brain disorder characterized by abnormalities of muscular tonicity, gross and fine motor skills, gait, and posture. It impacts motor control and muscle performance, which are emergent rehabilitation challenges in cerebral palsy children. Mirror therapy (MT) and transcranial direct current stimulation (tDCS) are novel treatment strategies to enhance muscle performance and motor control.</p><p><strong>Methods: </strong>A randomized clinical trial was conducted at Ghurki Hospital Lahore, Pakistan. One hundred and five spastic quadriplegic CP (SQCP) children aged three to seven years were included. Randomization was carried out using Version 1.0 of Randomized Allocation Software. Allocation was done to three groups (35 in each group) with a 1:1:1 ratio with a unique identity number. Group I (tDCS+MT+Routine Physical Therapy (RPT), Group II (MT+RPT), and Group III (tDCS + RPT). Each patient received ten sessions of tDCS and MT, lasting for 15 minutes per side along with 20 minutes of RPT five days a week for ten weeks. Motor control was assessed by the Fugl-Meyer assessment tool, and muscle performance was measured using an isokinetic dynamometer and assessed at baseline, the 2nd, and the 10th week of follow-up and was analyzed using SPSS version 26.</p><p><strong>Results: </strong>The results indicated a significant improvement after 10 weeks in the mean scores of motor control upper extremities, lower extremities, and trunk) with P-values of <0.000, <0.001, and <0.001, respectively. The mean scores of muscle performance (isokinetic strength) for right and left-sided elbow and knee flexors and extensors showed significant changes with P-values of 0.04, 0.01, 0.02, 0.02, 0.03, 0.05, 0.05, and 0.02, respectively. Similarly, muscle performance (isokinetic power) for these muscle groups also demonstrated significant changes, with P-values of 0.04, 0.01, 0.04, 0.02, 0.03, 0.05, 0.05, and 0.02, respectively.</p><p><strong>Conclusion: </strong>tDCS and MT in combination significantly impacted motor control and muscle performance, enhancing elbow and knee musculature strength and power among SQCP patients.</p><p><strong>Trial registration: </strong>IRCT20231227060542N1 on 26-01-2024 https://irct.behdasht.gov.ir/.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"1195-1216"},"PeriodicalIF":2.7,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}