Journal of Multidisciplinary Healthcare最新文献

{"title":"Construction of a Management Plan for Physical Activity Symptom Clusters in Hospitalized Stroke Patients.","authors":"Jialing Zhou, Jinxiu Li, Jianghong Tan","doi":"10.2147/JMDH.S579511","DOIUrl":"https://doi.org/10.2147/JMDH.S579511","url":null,"abstract":"<p><strong>Objective: </strong>To construct a scientifically sound and reliable management protocol for the physical activity symptom clusters in hospitalized stroke patients, based on the Symptom Management Theory (SMT).</p><p><strong>Methods: </strong>This methodological study employed a multi-step approach. First, a preliminary protocol was drafted based on a systematic literature review and best evidence summary. Second, a two-round Delphi expert consultation process was conducted to refine and validate the protocol. Statistical analysis included calculating the positive coefficient, authority coefficient (Cr), coefficient of variation (CV), and Kendall's coefficient of concordance (W).</p><p><strong>Results: </strong>Fifteen experts completed both consultation rounds. The expert positivity rates were 83.33% and 100%, respectively. The authority coefficients (Cr) were 0.89 and 0.91. The first round yielded a CV of 0.00-0.14 and a Kendall's W of 0.195 (<i>P</i> < 0.05). The second round yielded a CV of 0.00-0.11 and a Kendall's W of 0.160 (<i>P</i> < 0.05). The final protocol comprised 3 first-level domains, 14 second-level domains, and 31 third-level items, organized within the SMT framework of symptom experience, management strategies, and outcomes.</p><p><strong>Conclusion: </strong>The developed management protocol for the management protocol demonstrates strong scientific validity, reliability, and practical applicability. It serves as a valuable tool for healthcare professionals to develop personalized care plans, potentially enhancing rehabilitation outcomes and quality of life for stroke patients. Future studies are required to test its efficacy in multi-center trials.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"579511"},"PeriodicalIF":2.4,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12912056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146219786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mobile Application-Based Interventions to Improve Attention in Stroke Survivors: A Scoping Review.","authors":"Andri Nugraha, Cecep Eli Kosasih, Iqbal Pramukti, Vitriana Biben","doi":"10.2147/JMDH.S571115","DOIUrl":"https://doi.org/10.2147/JMDH.S571115","url":null,"abstract":"<p><strong>Background: </strong>Stroke is a major global cause of disability, and attention deficits are among the most common cognitive impairments in survivors. These deficits limit independence and hinder rehabilitation outcomes. Conventional post-stroke rehabilitation focuses primarily on motor recovery, while targeted cognitive rehabilitation, particularly attention training, remains underrepresented.</p><p><strong>Purpose: </strong>This scoping review aimed to identify mobile application-based interventions developed to improve attention in stroke survivors. The secondary aim was to describe the implementation settings of these interventions.</p><p><strong>Methods: </strong>This review followed the PRISMA-ScR Arksey and O'Malley frameworks. Systematic searches were conducted in PubMed, Scopus, EBSCO-host, and Google Scholar up to January 2025. Eligible studies included randomized controlled trials (RCTs), pilot RCTs, and quasi-experimental designs involving post-stroke patients with attentional deficits using mobile applications via smartphones or tablets. Methodological quality was appraised using the Joanna Briggs Institute (JBI) checklist for RCTs and the National Institutes of Health (NIH) tool for pre-post studies without a control group.</p><p><strong>Results: </strong>Eleven studies were included from 5840 identified records. Two types of mobile applications were identified: cognitive training applications (n = 4) incorporating structured exercises and telehealth support, and game-based rehabilitation applications (n = 7), emphasizing gamification and training tasks. The interventions were implemented in hospital-based and hybrid settings.</p><p><strong>Conclusion: </strong>Mobile applications show promise in post-stroke attentional rehabilitation, with evidence supporting cognitive training and game-based programs via tablets in hospital or hybrid settings and these interventions improve attention. However, methodological variability and heterogeneous protocols limit study comparability. Future research needs standardized frameworks and large clinical trials, supported by digital literacy among healthcare professionals, to strengthen clinical integration within stroke rehabilitation.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"571115"},"PeriodicalIF":2.4,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12911965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146219892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors Influencing Disease Onset and Surgical Outcomes in Moyamoya Disease.","authors":"Xuhua Cao, Liyi Wang, Zhizhao Ma, Wang Xi, Yanan Li, Shiyuan Zhang, Tao Zhang, Guozhu Sun","doi":"10.2147/JMDH.S561544","DOIUrl":"https://doi.org/10.2147/JMDH.S561544","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study is to explore the risk factors associated with the onset and clinical progression of moyamoya disease (MMD), as well as the outcomes of combined revascularization surgery (RS).</p><p><strong>Methods: </strong>A retrospective analysis was performed on the medical records of 226 individuals diagnosed with MMD who underwent combined <i>RS</i> at the Department of Neurosurgery in 2022. Binary logistic regression analysis was used to identify risk factors related to the occurrence of cerebral ischemia (CIS), postoperative complications, lateralization of MMD involvement, progression from unilateral to bilateral MMD, and disease severity in cases presenting with CIS. Surgical effectiveness was assessed during follow-up.</p><p><strong>Results: </strong>Hypertension (odds ratio [OR] = 1.816, 95% confidence interval [CI]: 1.031-3.197) and higher preoperative modified Rankin Scale scores (OR = 5.164, 95% CI: 1.145-23.295) were identified as independent risk factors for CIS. Male sex (OR = 4.219, 95% CI: 1.470-12.195) and age ≥ 50 years (OR = 3.979, 95% CI: 1.494-10.598) were independent predictors of postoperative complications following RS. No independent factors were associated with the affected side or bilateral progression of MMD (P > 0.05). Disease severity in patients with CIS was influenced by both Suzuki staging and age. The effective rate of <i>RS</i> at 3-6 months postoperatively was 96.46%.</p><p><strong>Conclusion: </strong>Early intervention is recommended, particularly for male patients and those with modifiable risk factors such as hypertension. <i>RS</i> should ideally be performed during the early stages of Suzuki classification and before the age of 50 to reduce the risk of postoperative complications. For patients with advanced Suzuki stage or aged ≥ 50 years, comprehensive perioperative risk assessments and tailored postoperative management strategies are essential to ensure optimal surgical outcomes.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"561544"},"PeriodicalIF":2.4,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12911982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146220049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depression and Quality of Life in Patients with Rheumatoid Arthritis: The Impact of Self-Disgust.","authors":"Cailin Chen, Xiaoqian Liu, Caixia Chen, Yongmei Lu, Sisi Xue, Lin Wen, Xiangwei Yang","doi":"10.2147/JMDH.S578454","DOIUrl":"https://doi.org/10.2147/JMDH.S578454","url":null,"abstract":"<p><strong>Background: </strong>Rheumatoid arthritis (RA) significantly impairs patients' quality of life. Psychological factors such as depression and self-disgust have been shown to be associated with quality of life; however, their interactions and combined effects remain unclear. Moreover, the level of self-disgust among Chinese patients with RA has not yet been investigated.</p><p><strong>Objective: </strong>To examine the mediating effects of self-disgust in the relationship between depression and quality of life among patients with RA, and to provide a reference for clinical practice aimed at improving patients' quality of life.</p><p><strong>Methods: </strong>This cross-sectional study was conducted at a tertiary general hospital in Guangzhou between August 2024 and February 2025, involving 342 patients with RA. Participants completed the General Information Questionnaire, the Questionnaire for the Assessment of Self-Disgust (QASD), the Hospital Anxiety and Depression Scale (HADS) and Quality of Life in RA Patients Scale. Univariate and Pearson correlation analyses were performed using SPSS 27.0, and mediation effects were tested with the Process plugin.</p><p><strong>Results: </strong>The mean scores of depression, the Quality of Life in RA Patients Scale and QASD were (9.01±4.97), (82.23±16.73) and (27.58±13.67), respectively. Depression was significantly correlated with quality of life (<i>r</i>=0.787, <i>P</i> < 0.001), depression was significantly correlated with self-disgust (<i>r</i>=0.804, <i>P</i> < 0.001), and quality of life was significantly correlated with self-disgust (<i>r</i>=0.727, <i>P</i> < 0.001). Self-disgust exhibited a partial mediating effect on the relationship between depression and quality of life in patients with RA, accounting for 20.60% of the total effect.</p><p><strong>Conclusion: </strong>Patients with RA have a relatively low quality of life. Self-disgust plays a partial mediating role between depression and quality of life in patients with RA. Nursing staff should pay attention to the assessment and screening of patients' depression and self-disgust, and implement targeted interventions to improve patients' quality of life.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"578454"},"PeriodicalIF":2.4,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12912071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146219815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nursing Approaches to Oral Implant Care in Patients with Chronic Systemic Conditions: An Integrative Review.","authors":"Ying Yang, Wentong Su, Xiaofen Liu","doi":"10.2147/JMDH.S573116","DOIUrl":"https://doi.org/10.2147/JMDH.S573116","url":null,"abstract":"<p><strong>Purpose: </strong>This integrative review synthesizes evidence on nursing approaches to oral implant care in patients with chronic systemic conditions (diabetes, osteoporosis, cardiovascular diseases) and examines how these conditions impact implant outcomes and how nursing interventions optimize the delivery of care.</p><p><strong>Methods: </strong>Systematic searches of PubMed, CINAHL, Scopus, and Embase (January 2010-April 2025) identified 45 studies (20 original research, 18 reviews, 7 guidelines). Quality assessment used Joanna Briggs Institute Critical Appraisal Tools and the AGREE II instrument. Data extraction focused on nursing interventions, clinical outcomes, and interprofessional collaboration strategies.</p><p><strong>Results: </strong>Chronic conditions significantly impact implant success: diabetes increases failure rates by 30-50% with HbA1c > 8.0%, osteoporosis causes 12-25% early failure in untreated patients, and cardiovascular diseases increase complications by 15-20%. Nurses play vital roles in patient education (92% of studies), systemic health monitoring (87%), and collaboration (84%). Key interventions demonstrated significant improvements: tailored education improved self-care by 57% (<i>p</i> < 0.01), risk assessment reduced complications by 35% (<i>p</i> < 0.01), and collaborative care improved coordination by 34% (<i>p</i> < 0.01). However, 62% of nurses reported inadequate training.</p><p><strong>Conclusion: </strong>Evidence supports personalized nursing care, systematic risk assessment, and interprofessional collaboration for optimal implant outcomes. Standardized guidelines and comprehensive training programs are urgently needed to enhance nursing competencies and address identified care gaps.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"573116"},"PeriodicalIF":2.4,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12912125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146219951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital Transformation and Team-Based Care: Pharmacists in Multidisciplinary Models - A Narrative Review.","authors":"Asma M Alshahrani, Rajalakshimi Vasudevan, Amjad Hmlan, Abdullah Mohammed Assiri, Ahmad Mohammed Asiri, Omar Ahmed M Asiri, Ali Abduh Mashni","doi":"10.2147/JMDH.S576298","DOIUrl":"https://doi.org/10.2147/JMDH.S576298","url":null,"abstract":"<p><strong>Background: </strong>Healthcare systems worldwide are increasingly challenged by the rise in chronic diseases, aging populations, and the growing demand for personalized care. Traditional models, where healthcare professionals operate independently with limited interdisciplinary communication are proving insufficient to meet the complex and interconnected needs of modern patients.</p><p><strong>Objective: </strong>This review explores the growing importance of innovative and multidisciplinary approaches in healthcare, with a specific focus on the expanding role of pharmacists and the integration of digital tools. Unlike reviews that examine either multidisciplinary care or digital health in isolation, this review integrates evidence on how pharmacists function as clinical and digital connectors within multidisciplinary care models across diverse health systems.</p><p><strong>Methods: </strong>This narrative review synthesized evidence on multidisciplinary care models that integrate pharmacists and digital tools. PubMed, Scopus, and Google Scholar were searched (2015-March 2024) using terms related to multidisciplinary care, pharmacists/clinical pharmacy, and digital health (e.g. EHRs, telehealth, AI, mHealth). English-language peer-reviewed studies describing pharmacist integration in team-based and/or technology-enabled care were included; grey literature and non-peer-reviewed sources were excluded.</p><p><strong>Results: </strong>Across multiple care models, pharmacist integration in multidisciplinary teams was associated with improved chronic disease indicators (eg, better blood pressure or glycaemic control), fewer medication-related problems, including reports of reduced medication errors (eg, ~45% reduction in rural telepharmacy settings), and reduced avoidable hospitalizations/readmissions in transition-of-care settings. Digital innovations such as clinical decision support and telehealth platforms further enhanced coordination and continuity of care, enabling timely medication optimization and follow-up. Case studies from the UK, Canada, Saudi Arabia, Australia, India and South Africa selected LMICs illustrate context-adapted and scalable approaches.</p><p><strong>Conclusion: </strong>When supported by enabling policy frameworks and robust digital infrastructure, multidisciplinary healthcare models offer a powerful solution to many of today's healthcare challenges. Empowering pharmacists, investing in interoperable technologies, and reforming education and reimbursement structures are critical next steps toward resilient, patient-centered healthcare systems.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"576298"},"PeriodicalIF":2.4,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12912030/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146219963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acupuncture's Regulatory Role in Glial Cells and Their Interactions for Antidepressant Effects: A Review of Research Progress.","authors":"Jing Cao, Lian Yang, Deguang Ding, Xiaolei Zhang, Nana Ding, Fengmin Ding, Qinglai Bian, Jiaxu Chen","doi":"10.2147/JMDH.S581593","DOIUrl":"https://doi.org/10.2147/JMDH.S581593","url":null,"abstract":"<p><p>The clinical management of depression presents significant challenges. While acupuncture has shown efficacy in alleviating depressive symptoms, the underlying mechanisms through which it exerts its antidepressant effects remain incompletely understood. Recent research has underscored the crucial role of glial cells in the pathophysiology of depression. This discovery opens a novel and promising avenue for investigating the mechanisms underlying acupuncture's antidepressant actions. Based on clinical evidence supporting the use of acupuncture in treating depression, this article reviews recent studies on how acupuncture influences the glial cell network. This is the first review of studies examining the effects of acupuncture on glial cells in depression. The review encompasses several key aspects, including microglial polarization and associated inflammatory signaling pathways, the role of astrocytes in maintaining metabolic homeostasis, the processes of oligodendrocyte differentiation and myelin repair, as well as the intricate interactions among these three types of glial cells. However, this paper also has certain limitations, such as the majority of mechanistic evidence deriving from animal models, and due to the heterogeneity of acupuncture protocols and the lack of human causal data.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"581593"},"PeriodicalIF":2.4,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12912032/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146219996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Home Exercise Therapy in Patients with Stable Congestive Heart Failure (CHF): A Scoping Review.","authors":"Iwan Shalahuddin, Udin Rosidin, Theresia Eriyani, Indra Maulana, Sandra Pebrianti","doi":"10.2147/JMDH.S582501","DOIUrl":"https://doi.org/10.2147/JMDH.S582501","url":null,"abstract":"<p><strong>Background: </strong>Congestive Heart Failure (CHF) is a chronic condition that drastically lowers patients' quality of life. In addition to pharmaceutical treatment, physical activity is crucial for improving cardiovascular function. However, limited access to health facilities makes home exercise therapy a more realistic option for many patients with stable conditions.</p><p><strong>Objective: </strong>To identify and map scientific evidence related to the application of home exercise therapy in stable CHF patients and the clinical outcomes it produces, using a scoping review technique.</p><p><strong>Methods: </strong>The search was conducted using keywords related to the predetermined topic of discussion by applying the PICO approach with keywords about adults with congestive heart failure, home exercise therapy, and cardiac rehabilitation. The databases used in the article search were PubMed, Science Direct, Research Gate, Sage Journals, mbase, Web of Science, and Google Scholar.The literature search was done in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) standards. Articles published in the previous ten years were selected using preset inclusion and exclusion criteria.</p><p><strong>Results: </strong>The analysis indicated that several types of home exercise treatment, such as light to moderate intensity aerobic exercise, breathing exercises, and structured activity programs, were safe and useful in enhancing functional ability, quality of life, and decreasing rehospitalization rates. Regularity of exercise, family support, and simple monitoring by health workers greatly influenced the success of the intervention.</p><p><strong>Conclusion: </strong>Home exercise therapy is a feasible and practical approach for patients with stable CHF. Exercise programs tailored to the patient's condition can help improve cardiovascular function while positively impacting psychological and social aspects.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"582501"},"PeriodicalIF":2.4,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12912152/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146219932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Roles and Influence of Nursing Assistants in Integrated Medical and Elderly Care Institutions: A Qualitative Study.","authors":"Anni Song, Xiaoling Yan, Liqun Yao, Mengwei Shao, Huiyue Zhou, Na Zhou, Huibin Si, Jiao Zhou, Xiaowan Li, Ying Li","doi":"10.2147/JMDH.S576618","DOIUrl":"https://doi.org/10.2147/JMDH.S576618","url":null,"abstract":"<p><strong>Background: </strong>The Chinese government has implemented policies to establish integrated medical and elderly care services (IMECS) institutions and develop the nursing assistants (NAs) to alleviate healthcare workforce shortages. However, the role definition of NAs remains ambiguous. Insights from registered nurses (RNs) can help clarify their roles and impacts.</p><p><strong>Objective: </strong>This study aimed to explore the roles and impacts of NAs in integrated medical and IMECS institutions.</p><p><strong>Methods: </strong>A descriptive qualitative study was conducted using purposive sampling at the largest IMECS institution in Zhengzhou, Central China, from December 2024 to February 2025. Semi-structured interviews were conducted with 23 RNs. Thematic analysis was employed to analyze the interview data.</p><p><strong>Findings: </strong>Four themes and twelve sub-themes emerged from the analysis: 1) role identity, 2) high role expectations, 3) role conflict, and 4) low role authorization.</p><p><strong>Conclusion: </strong>While RNs value NAs' contributions, challenges in training and competency lead to job instability and restricted practice. Tailored strategies are recommended, with future multi-center studies needed for broader validation.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"576618"},"PeriodicalIF":2.4,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12912146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146220013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Choroidal Thickness and Postural Stability in Young Adults: Exploring Ocular Contributions to Balance and Fall Prevention.","authors":"Mohammed M Althomali, Abdulaziz M Alkhudhair, Muteb K Alanazi, Wafa M Alotaibi, Sulaiman Aldakhil, Saleh R Alshammeri, Ahmad A Alharbi, Mohammed S Alhazmi","doi":"10.2147/JMDH.S566806","DOIUrl":"https://doi.org/10.2147/JMDH.S566806","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the relationship between choroidal thickness and postural stability in healthy young adults, focusing on the influence of refractive error and choroidal thickness distribution across quadrants.</p><p><strong>Patients and methods: </strong>A cross-sectional study was conducted with 24 young adults (19 men, 5 women; mean age, 22 ± 2.06 years). Refractive error was measured using an autorefractor, and choroidal thickness was assessed with optical coherence tomography. Postural stability was evaluated using a force platform under quiet stance and one-legged stance conditions. Choroidal thickness was analyzed across quadrants and rings, and its correlation with postural sway parameters was determined using univariate analyses.</p><p><strong>Results: </strong>The mean choroidal thickness was 280 ± 77.51 μm, with the nasal quadrant being the thinnest and the inferior quadrant the thickest. Myopic participants had thinner choroids (mean, 273 ± 77.25 μm) compared to non-myopes (mean, 288 ± 77.08 μm). A positive correlation (r = 0.279, P < 0.001) was found between choroidal thickness and refractive error. In quiet stance, increased choroidal thickness was negatively correlated with anterior-posterior sway but positively correlated with medial-lateral sway. During one-legged stance, choroidal thickness was negatively correlated with most postural sway measures, except for maximum medial-lateral sway.</p><p><strong>Conclusion: </strong>Choroidal thickness is associated with refractive error and postural stability. Regional differences in choroidal thickness may play a role in balance control, highlighting the potential relevance of ocular structural health to mechanisms underlying balance control and fall risk. Further research is needed to explore the mechanisms linking choroidal dynamics and postural control.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"566806"},"PeriodicalIF":2.4,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12912017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146219676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}