Journal of Multidisciplinary Healthcare最新文献

{"title":"Patients' Experiences with an Interdisciplinary Team Assessment of Chronic Pain: A Qualitative Interview Study.","authors":"Martin Bystad, Ida Solhaug, Ida Pauline Høilo Granheim, Rolf Wynn","doi":"10.2147/JMDH.S526302","DOIUrl":"10.2147/JMDH.S526302","url":null,"abstract":"<p><strong>Background: </strong>Chronic pain is a widespread issue, and it is important to find interventions that are effective and valued by patients. At the study hospital, an interdisciplinary approach is often used, involving an assessment by a psychologist, physiotherapist, and doctor. We wanted to examine patients' experiences with this interdisciplinary approach.</p><p><strong>Methods: </strong>We conducted semi-structured interviews with nine patients at the Pain Department at the University Hospital of North Norway. The interviews were conducted in January and February 2023. The interviews were analyzed using a phenomenological approach.</p><p><strong>Results: </strong>Overall, our results suggest that an interdisciplinary approach is perceived as beneficial by patients with chronic pain. Four themes were highlighted. The first theme was that patients felt their pain was understood in a holistic manner. The second theme was that the participants felt seen and understood. The third theme emphasized the value of having further actions recommended and initiated. The fourth theme was a feeling of being overwhelmed by an interdisciplinary approach.</p><p><strong>Conclusion: </strong>A majority of the participants found an interdisciplinary approach to be helpful. However, some patients may find it challenging to meet the entire interdisciplinary team at once.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"5103-5111"},"PeriodicalIF":2.4,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12375322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Journey Mapping for Symptom Management in Adolescents with Depression: A Longitudinal Qualitative Study of Dynamic Patient-Centered Pathways.","authors":"Shihan Fang, Fazhan Chen, Xiaoying Zhu, Jing Bian, Jinshen Zhang, Yating Wang, Yanbo Wang","doi":"10.2147/JMDH.S533788","DOIUrl":"10.2147/JMDH.S533788","url":null,"abstract":"<p><strong>Purpose: </strong>This longitudinal qualitative study aimed to explore the dynamic symptom management journeys of adolescents with depression, integrate Symptom Management Theory (SMT) with journey mapping, and identify stage-specific characteristics, emotional experiences, and unmet needs across the illness trajectory to inform targeted interventions.</p><p><strong>Methods: </strong>A longitudinal qualitative design with reflexive thematic analysis (RTA) was adopted. Twelve adolescents with depression (aged 12-18 years) were recruited from a tertiary psychiatric hospital in Zhejiang Province, China. Data were collected through semi-structured interviews at three time points: baseline, 1-month, and 3-month follow-ups, supplemented by observation notes and self-management diaries. Journey mapping was used to visualize dynamic interactions across four phases (symptom recognition, help-seeking, treatment engagement, and daily management), with longitudinal integration of data to track temporal changes.</p><p><strong>Results: </strong>The symptom management journey was non-linear, characterized by distinct emotional and behavioral patterns across phases: numbness and self-loathing during symptom recognition (eg, self-harm as emotional outlet, somatization like headaches); fear and shame in help-seeking (eg, passive medical-seeking due to family coercion, reliance on online support); oscillating hope and skepticism during treatment (eg, selective adherence to preferred therapies like hypnotherapy over Modified Electroconvulsive Therapy) and fluctuating recovery confidence in daily management (eg, re-engaging with interests such as painting or running, forming peer support networks). Key barriers included familial misunderstanding, academic stigma, and inadequate relapse prevention tools, while facilitators involved personalized coping strategies and incremental family adaptation.</p><p><strong>Conclusion: </strong>This study captures the dynamic, contextually embedded nature of symptom management in adolescent depression through longitudinal journey mapping, revealing critical tensions between individual agency and multi-level contextual influences (family, school, healthcare). The findings contribute in-depth qualitative insights into stage-specific needs, supporting the development of patient-centered, phase-adapted interventions.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"5039-5060"},"PeriodicalIF":2.4,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12376070/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Gastroesophageal Reflux Disease, Barrett's Esophagus and Ear Disorders: A Mendelian Randomization Study.","authors":"Wen Zhao, Xu-Rui Hao, Han-Lin Zhao, Ye-Sen Ma, Han-Xu Li, Qian Yang, Jian-Ming Jiang, Hai-Yan Bai","doi":"10.2147/JMDH.S530915","DOIUrl":"10.2147/JMDH.S530915","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to examine the correlation between gastroesophageal reflux disease (GERD), Barrett's esophagus (BE), and ear disorders using Mendelian randomization (MR).</p><p><strong>Methods: </strong>For GERD, BE, and ear disorders, GWAS genetic data from individuals of European ancestry in the IEU GWAS database (https://gwas.mrcieu.ac.uk/) was utilized in this study. Three MR methods were applied for preliminary analysis, with causal estimates determined using the inverse variance weighted method. Sensitivity analysis was conducted to assess heterogeneity and pleiotropy.</p><p><strong>Results: </strong>Potential effects of genetically predicted GERD on ear disorders were identified in this study. GERD was associated with Ménière's disease (OR = 1.334, 95% CI: 1.073-1.671, <i>p</i> = 0.009), sensorineural hearing loss (OR = 1.127, 95% CI: 1.019-1.245, <i>p</i> = 0.019), vestibular dysfunction (OR = 1.178, 95% CI: 1.025-1.354, <i>p</i> = 0.021), constant tinnitus (OR = 1.019, 95% CI: 1.009-1.029, <i>p</i> = 0.0003), tinnitus occurring most of the time (OR = 1.007, 95% CI: 1.001-1.012, <i>p</i> = 0.019), and occasional tinnitus (OR = 1.014, 95% CI: 1.005-1.023, <i>p</i> = 0.002). Higher GERD levels were linked to an increased risk of these ear disorders. For individuals who never experienced tinnitus (OR = 0.939, 95% CI: 0.923-0.957, <i>p</i> = 1.2721E-11), elevated GERD levels were associated with a reduced likelihood of never experiencing tinnitus. No causal association was found between GERD and otitis media (OR = 1.093, 95% CI: 0.884-1.352, <i>p</i> = 0.412). BE demonstrated no causal relationship with ear disorder risk.</p><p><strong>Conclusion: </strong>Under MR assumptions, the findings of this study indicate that GERD may increase the risk of tinnitus, Ménière's disease, vestibular dysfunction, and sensorineural hearing loss.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"5061-5074"},"PeriodicalIF":2.4,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12375315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health Literacy Profiles and Disparities Among Adolescents and Implications in Ethiopia.","authors":"Adamu Amanu Asari, Ameyu Godesso, Zewdie Birhanu","doi":"10.2147/JMDH.S532819","DOIUrl":"10.2147/JMDH.S532819","url":null,"abstract":"<p><strong>Background: </strong>Health literacy (HL) among adolescents is a crucial public health and health equity issue. Currently, research on HL among adolescents is expanding to support effective, evidence-based interventions. However, in Ethiopia, it remains under-researched. Thus, this study focuses on HL among adolescents in Ethiopia. It examines adolescents' HL profiles, identifies and analyzes existing HL inequalities, and ascertains the implications for developing targeted public health strategies and educational programs aimed at improving HL among adolescents.</p><p><strong>Methods: </strong>This study employed a school-based, cross-sectional survey design. Data collection took place in January and February 2024. Data analysis comprised both descriptive and inferential statistics, using SPSS version 27.0. Descriptive statistics summarized sociodemographics and HL scores and statuses. Chi-square tests examined disparities in HL across these sociodemographics. Binary logistic regression analyses identified significant predictors of HL among adolescents.</p><p><strong>Results: </strong>A total of 722 adolescents participated in this study, and only about one-quarter of them had adequate HL, with extreme disparities observed across sociodemographic and related factors. Chi-square tests revealed significant associations between HL and school type, parents' education, household income, Internet access, academic performance, interest in health matters, and outlooks on life/futurity. Logistic regression analyses further indicated that respondents having fathers with high education (AOR=1.824, 95% CI=1.126, 2.954), mothers with high education (AOR=1.942, 95% CI=1.154, 3.268), middle household income (AOR=3.819, 95% CI=2.197, 6.636), high household income (AOR=4.583, 95% CI=2.582, 8.137), high academic performance (AOR=3.275, 95% CI=1.472, 7.285), and positive outlooks on life/futurity (AOR=1.948, CI=1.060, 3.582) were more likely to have adequate HL. Respondents lacking Internet access (AOR=0.146, 95% CI=0.069, 0.309) and having low interest in health matters (AOR=0.196, 95% CI=0.096, 0.401) were less likely to have adequate HL.</p><p><strong>Conclusion: </strong>This study investigates HL among adolescents in Ethiopia, revealing a high prevalence of inadequate HL and disparities that contribute to broader health inequalities in society. To address this, the study calls for targeted policies and interventions, including formal HL education in schools.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"5025-5038"},"PeriodicalIF":2.4,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12374705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Braden Score-Guided Targeted Nursing Interventions on Preventing Intraoperative Pressure Ulcers in Aortic Dissection Surgery.","authors":"Qiao-Zhi Wang, Wen-Cheng Jia, Yu-Quan Tian","doi":"10.2147/JMDH.S529708","DOIUrl":"10.2147/JMDH.S529708","url":null,"abstract":"<p><strong>Objective: </strong>This prospective randomized controlled study aimed to evaluate the effect of Braden score-guided targeted nursing interventions on preventing intraoperative pressure ulcers in aortic dissection (AD) surgery.</p><p><strong>Methods: </strong>A total of 120 patients who underwent AD surgery at the hospital between December 2023 and December 2024 were selected and randomly assigned to either the study group or the control group, with 60 patients in each group. The control group received routine nursing care, while the study group received targeted nursing interventions guided by the Braden score in addition to routine care. Statistical analyses were conducted to compare the results between the two groups.</p><p><strong>Results: </strong>Following the implementation of targeted nursing interventions guided by the Braden score, the total nursing behavior scores for pressure ulcer prevention (95.67±3.41 vs 83.95±5.16), including all individual dimension scores (preoperative care: 56.71±2.43 vs 48.53±4.91; intraoperative care: 22.39±1.68 vs 17.64±2.75; postoperative care: 13.65±2.49 vs 10.48±2.51), were significantly higher in the study group compared to the control group (<i>P</i> < 0.05). The incidence of intraoperative pressure ulcers was notably lower in the study group (2.5%) than in the control group (17.5%) (<i>P</i> < 0.05). Additionally, the pressure ulcer area was significantly smaller (2.11±0.36 vs 4.98±1.14 cm²), and the duration of pressure ulcers was markedly shorter in the study group compared to the control group (2.73±1.24 vs 7.86±1.65 days) (<i>P</i> < 0.05). Nursing satisfaction levels were also significantly higher in the study group (97.5% vs 82.5%) (P < 0.05).</p><p><strong>Conclusion: </strong>Targeted nursing interventions guided by the Braden score demonstrated effectiveness in identifying risks of intraoperative pressure ulcers. The designed interventions enhanced the quality of nursing care in the operating room, reduced the incidence of pressure ulcers, and improved patient satisfaction.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"5015-5023"},"PeriodicalIF":2.4,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12372843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Initial Treatment Strategies Show No Survival Difference in Early-Stage Salivary Gland Mucosa-Associated Lymphoid Tissue Lymphoma.","authors":"Shi-Ping Yang, Jing Zhu, Xin-Yi Qiu, Zhi-Cong Hong, San-Gang Wu","doi":"10.2147/JMDH.S538452","DOIUrl":"10.2147/JMDH.S538452","url":null,"abstract":"<p><strong>Purpose: </strong>Given the indolent nature of mucosa-associated lymphoid tissue (MALT) lymphoma, immediate intervention is not always necessary, and a consensus on the optimal treatment modality remains elusive. This study aimed to evaluate survival outcomes of different initial treatments for early-stage (stage I-II) salivary gland MALT lymphoma.</p><p><strong>Methods: </strong>Using data from the Surveillance, Epidemiology, and End Results program, we included patients diagnosed between 2000 to 2021. Initial treatments included surgery alone, radiotherapy alone, surgery combined with radiotherapy, chemotherapy alone, or observation. The chi-square test, Kaplan-Meier method, and multivariate Cox proportional-hazards models were used for statistical analyses.</p><p><strong>Results: </strong>A total of 892 patients were included. Tumor location was known for 859 patients, with 740 (86.1%) located in the parotid gland, 116 (13.5%) in the submandibular gland, and 3 (0.3%) in the sublingual gland. Of the patients, 237 (26.6%) underwent surgery alone, 202 (22.6%) received radiotherapy alone, 170 (19.1%) underwent surgery combined with radiotherapy, 53 (5.9%) received chemotherapy alone, and 230 (25.8%) with observation. Submandibular gland tumor patients were more likely to receive radiotherapy alone, chemotherapy alone, or observation, while parotid gland tumor patients preferred surgery or surgery combined with radiotherapy (P<0.001). Over time, the proportion of observation cases increased (P=0.004). The median follow-up time was 92 months. The 8-year cancer-specific survival rates for patients undergoing surgery alone, radiotherapy alone, surgery combined with radiotherapy, chemotherapy alone, and observation were 96.1%, 94.9%, 97.0%, 92.1%, and 95.5%, respectively (P=0.827). The 8-year OS rates for these groups were 79.7%, 84.5%, 86.3%, 77.7%, and 79.5%, respectively (P=0.132). Multivariate analysis showed that initial treatment modality did not significantly affect survival outcomes. Sensitivity analyses also showed similar outcomes for the five treatment groups across different subgroups. Age and gender were independent prognostic factors associated with survival outcomes.</p><p><strong>Conclusion: </strong>Our study highlights that early-stage salivary gland MALT lymphoma is characterized by a female predominance and an increasing trend toward observation as a management strategy. The lack of significant survival differences across treatment modalities suggests that the choice of initial treatment may be less critical than patient-specific factors such as age and gender. These findings advocate for personalized treatment approaches and underscore the importance of further research to better understand the underlying mechanisms driving gender disparities and the long-term outcomes of conservative management strategies.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"5001-5013"},"PeriodicalIF":2.4,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12360379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144883014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research on the Implementation Status and Optimization Path of \"Internet + Nursing Service\" from the Perspective of Grade Hospital Difference: A Multi-Dimensional Empirical Study Based on Online Nurses in Quzhou City.","authors":"Wenxian Xu, Chao Jiang, Liping Xu, Ting Qiu","doi":"10.2147/JMDH.S532942","DOIUrl":"10.2147/JMDH.S532942","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to explore the hierarchical management model of \"Internet + Nursing Services\" in prefecture-level regions, and provide targeted management strategies and improvement measures for managers of hospitals at different levels, so as to improve the overall quality and effectiveness of \"Internet + Nursing Services\" and promote the sustainable development of \"Internet + Nursing Services\".</p><p><strong>Patients and methods: </strong>A cross-sectional study was conducted on online nurses from different grades of hospitals contracted with \"Zheli Nursing\" in Quzhou City using cluster sampling method, to compare the differences in cognition, service willingness, service experience, risk perception, and obtained policy support among online nurses from different grades of hospitals in carrying out \"Internet + Nursing Services\".</p><p><strong>Results: </strong>Online nurses in high-level hospitals have advantages in cognition of knowledge related to \"Internet + Nursing Services\", service willingness, and service capabilities, but they face challenges in occupational safety and adaptation to complex environments. In contrast, online nurses in low-level hospitals have insufficient cognition of relevant knowledge about \"Internet + Nursing Services\", low service willingness, and concerns about road safety and medical violence, and they receive relatively less policy support and other issues.</p><p><strong>Conclusion: </strong>This study found significant quantitative differences in multiple dimensions among online nurses from different graded hospitals in Quzhou during the provision of \"Internet + Nursing Services\", providing scientific basis and practical guidance for optimizing the hierarchical management of \"Internet + Nursing Services\".</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"4989-4999"},"PeriodicalIF":2.4,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12358137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144873610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing DeepSeek-R1 for Clinical Decision Support in Multidisciplinary Laboratory Medicine.","authors":"Qinpeng Li, Lili Zhan, Xinjian Cai","doi":"10.2147/JMDH.S538253","DOIUrl":"10.2147/JMDH.S538253","url":null,"abstract":"<p><strong>Background: </strong>Recent advancements in artificial intelligence (AI), particularly with large language models (LLMs), are transforming healthcare by enhancing diagnostic decision-making and clinical workflows. The application of LLMs like DeepSeek-R1 in clinical laboratory medicine demonstrates potential for improving diagnostic accuracy, supporting decision-making, and optimizing patient care.</p><p><strong>Objective: </strong>This study evaluates the performance of DeepSeek-R1 in analyzing clinical laboratory cases and assisting with medical decision-making. The focus is on assessing its accuracy and completeness in generating diagnostic hypotheses, differential diagnoses, and diagnostic workups across diverse clinical cases.</p><p><strong>Methods: </strong>We analyzed 100 clinical cases from <i>Clinical Laboratory Medicine Case Studies</i>, which includes comprehensive case histories and laboratory findings. DeepSeek-R1 was queried independently for each case three times, with three specific questions regarding diagnosis, differential diagnoses, and diagnostic tests. The outputs were assessed for accuracy and completeness by senior clinical laboratory physicians.</p><p><strong>Results: </strong>DeepSeek-R1 achieved an overall accuracy of 72.9% (95% CI [69.9%, 75.7%]) and completeness of 73.4% (95% CI [70.5%, 76.2%]). Performance varied by question type: the highest accuracy was observed for diagnostic hypotheses (85.7%, 95% CI [81.2%, 89.2%]) and the lowest for differential diagnoses (55.0%, 95% CI [49.3%, 60.5%]). Notable variations in performance were also seen across disease categories, with the best performance observed in genetic and obstetric diagnostics (accuracy 93.1%, 95% CI [84.0%, 97.3%]; completeness 86.1%, 95% CI [76.4%, 92.3%]).</p><p><strong>Conclusion: </strong>DeepSeek-R1 demonstrates potential for a decision-support tool in clinical laboratory medicine, particularly in generating diagnostic hypotheses and recommending diagnostic workups. However, its performance in differential diagnosis and handling specific clinical nuances remains limited. Future work should focus on expanding training data, integrating clinical ontologies, and incorporating physician feedback to improve real-world applicability. DeepSeek-R1 and the new versions under development may be promising tools for non-medical professionals and professionals in medical laboratory diagnoses.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"4979-4988"},"PeriodicalIF":2.4,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144873536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Study on the Risk Factors of Abnormal Mental Health Status in General Physical Examination Population.","authors":"Ying Che, Jing Yan, Honghai He, Peng Wang","doi":"10.2147/JMDH.S521179","DOIUrl":"10.2147/JMDH.S521179","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to investigate the mental health status of the general population and its risk factors.</p><p><strong>Patients and methods: </strong>In this cross-sectional study, a total of 10278 individuals aged 12 and above who underwent health examinations were included. Participants completed self-administered questionnaires, the Symptom Checklist-90 (SCL-90), and the Stress Self-Assessment Questionnaire-53 (SSQ-53), to collect general information, mental health status, and stress level information. Metabolism-related hematological examinations were also conducted.</p><p><strong>Results: </strong>Based on the criterion of having a positive total score on the SCL-90 scale and/or a positive score on any factor of the scale, 3394 positive subjects (33.0%) were detected and classified as the abnormal psychological state group (positive group), while the remaining subjects served as the control group. There are differences between the two groups in terms of age (and age structure) and gender (female). The positive group had significantly higher in the SCL-90 total score and each factor score, as well as the SSQ-53 total score and each dimension score (including the proportion of abnormal scores in each dimension) (p<0.001). In the positive group, body mass index (BMI) (p<0.001) and triglycerides (p=0.001) were significantly higher than those in the control group, while high-density lipoprotein cholesterol (p<0.024) was significantly lower. Additionally, the abnormal proportions of BMI (p<0.001), white blood cell (WBC) count (p<0.001), and fasting plasma glucose levels (p=0.006) were significantly higher in the positive group. Logistic regression analysis revealed that adolescents (aged 12-18), females, abnormal BMI (overweight or obesity), and abnormal WBC count were risk factors for positive SCL-90 scores (P<0.05).</p><p><strong>Conclusion: </strong>There is a strong correlation between chronic metabolic diseases, inflammation, and stress-related mental and psychological disorders, necessitating active management of these physical issues. More attention should be paid to the mental health of women and adolescents.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"4969-4977"},"PeriodicalIF":2.4,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144873535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep Disorders in Young and Middle-Aged Adults with Acute Leukemia Undergoing Chemotherapy: A Qualitative Study from a Biopsychosocial Perspective.","authors":"Li Yu, Ying Jiang, Qin Zhou","doi":"10.2147/JMDH.S541748","DOIUrl":"10.2147/JMDH.S541748","url":null,"abstract":"<p><strong>Background and objectives: </strong>Sleep disorders frequently affect acute leukemia patients during chemotherapy, significantly impacting treatment outcomes and quality of life. Using the biopsychosocial model, this study explores young and middle-aged patients' perceptions and influencing factors of sleep disturbances to guide targeted interventions.</p><p><strong>Methods: </strong>Purposive sampling method was used to select 16 patients from the Department of Hematology of a tertiary hospital in Yantai City from December 2024 to January 2025 for semi-structured interviews, based on the biopsychosocial model, and Colaizzi's seven-step analysis method was used to refine the themes.</p><p><strong>Results: </strong>Seven themes were extracted: 1) Chemotherapy and the physiological burden of the disease itself (discomfort symptoms such as body pain and fatigue, particularly severe sleep problems during the induced remission period); 2) The physical and mental reactions caused by the uncertainty of disease progression and treatment (anxiety about the condition and treatment, fear of disease progression, and concern about recurrent pain); 3) Cognitive and emotional distress towards sleep (excessive sleep expectations, rumination further affecting sleep); 4) Polarization in coping (actively implementing self-regulation and generating negative avoidance thoughts); 5) Medical environment and institutional barriers (poor hospitalization environment, unmet sleep management needs of medical staff); 6) Economic and role pressures (heavy economic pressure, insufficient social support); 7) Family and peer relationships (yearning for family support and striving to establish peer support).</p><p><strong>Conclusion: </strong>Young and Middle-Aged Adults leukemia patients during chemotherapy have poor sleep quality, which is influenced by multiple biological, psychological, and social factors. These findings provide new insights into the challenges of patient-centered sleep management during chemotherapy and highlight the inadequacy of psychosocial support and institutional care. Clinicians should combine these influencing factors to develop targeted interventions to improve patients' sleep quality and enhance their quality of life.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"4957-4968"},"PeriodicalIF":2.4,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357553/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144873612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}