Journal of Multidisciplinary Healthcare最新文献

{"title":"A Multidisciplinary Intragastric Balloon Care Pathway for Weight Management in a Tertiary Malaysian Centre: Clinical Practice Framework.","authors":"Theeran Gill, Guo Hou Loo, Guhan Muthkumaran, Nik Ritza Kosai","doi":"10.2147/JMDH.S590735","DOIUrl":"https://doi.org/10.2147/JMDH.S590735","url":null,"abstract":"<p><strong>Background: </strong>Obesity is a chronic disease with major metabolic, physical, and psychosocial consequences. Intragastric balloon (IGB) therapy is a minimally invasive endoscopic or device-based option that can bridge the gap between lifestyle intervention and bariatric surgery for selected patients. Despite expanding use, many centres lack a standardized multidisciplinary pathway to ensure appropriate selection, peri-procedural safety, nutrition support, and structured follow-up.</p><p><strong>Objective: </strong>To describe the development and implementation framework of a standardized multidisciplinary IGB care pathway in a tertiary Malaysian centre, including patient selection, peri-procedural pharmacotherapy, nutritional protocols, safety monitoring, and follow-up scheduling.</p><p><strong>Methods: </strong>This is a clinical practice framework describing protocol development based on local practice needs, alignment with national recommendations, and evidence-informed considerations. The pathway consolidates: (1) patient selection and assessment algorithm, (2) standardized medication regimen, (3) dietitian-led post-procedure nutritional support options, and (4) structured clinic follow-up milestones.</p><p><strong>Practice framework: </strong>The pathway defines indications (including Asian population considerations), anticipated efficacy expectations, adverse effect management, serious complication awareness, nutrition regimens using commonly available oral nutritional supplements, and staged follow-up at 2 weeks, 4 months, 8 months, and 1 year. It also outlines local device options used in the institution and key counseling points for durability and weight regain prevention.</p><p><strong>Conclusion: </strong>A standardized multidisciplinary intragastric balloon care pathway provides a structured approach to delivering IGB therapy in routine clinical practice. Its clinical effectiveness requires validation through prospective outcome-based studies. It may serve as a practical reference for centres developing endobariatric services in similar healthcare settings.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"590735"},"PeriodicalIF":2.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13143832/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does Family Doctor Contracting Improve the Health of the Elderly: An Empirical Study from Beijing, China.","authors":"Bo Lv, Zhaoyang Wang, Kai Meng","doi":"10.2147/JMDH.S596260","DOIUrl":"https://doi.org/10.2147/JMDH.S596260","url":null,"abstract":"<p><strong>Background: </strong>Amid rapid population aging and the rising prevalence of chronic diseases in China, family doctor contract services have become a key healthcare reform aimed at strengthening primary care. The elderly are a priority group for these services. This study examines their specific relationship on the health of older adults, providing a scientific basis for expanding the services and improving health outcomes in this population.</p><p><strong>Methods: </strong>This study employed a cross-sectional research design. A cluster sampling method was used to select 2052 elderly individuals aged 60 years and above from a community in District F, Beijing. A total of 1814 valid questionnaires were collected, yielding an effective response rate of 88.40%. To analyze the relationship between family doctor contracting and the health status of the elderly, the PSM model was applied to construct a control group with similar observable characteristics, thereby addressing self-selection bias. Additionally, the 2SLS model was adopted, incorporating instrumental variables to control for potential endogeneity issues.</p><p><strong>Results: </strong>The proportion of elderly individuals who signed contracts with family doctors was relatively low, at 21.72%. The average self-rated physical health score was 10.18. In the PSM analysis, the effect sizes for kernel matching, k-nearest neighbor matching, and radius matching were -0.17, -0.09, and -0.12, respectively. The preference for primary medical and health institutions as the first point of care passed the weak instrumental variable test (<i>F</i>=36.25). The regression coefficient derived from the 2SLS method was -0.02.</p><p><strong>Conclusion: </strong>The willingness to sign up for family doctor services among the elderly in Beijing remains generally low. Health status is influenced by chronic disease, activity, education, and occupation, yet enrollment alone yields no significant improvement. This points to ineffective service engagement. Stronger policy authority, better mechanisms, aligned services, and enhanced execution and trust are urgently needed to realize family doctors' role.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"596260"},"PeriodicalIF":2.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13142731/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adherence to HPV-Based Cervical Cancer Screening: A Concept Analysis for Nursing and Midwifery Practice.","authors":"Cristina Lumia, Simona Fumagalli, Marianna Martinelli, Davide Ausili, Antonella Nespoli","doi":"10.2147/JMDH.S601358","DOIUrl":"https://doi.org/10.2147/JMDH.S601358","url":null,"abstract":"<p><p>Human papillomavirus (HPV) infection is one of the most common sexually transmitted infections worldwide and a necessary cause of cervical cancer. Although HPV vaccination and HPV-based cervical cancer screening have strengthened prevention strategies, participation across screening and follow-up pathways remains suboptimal in many settings, limiting programme effectiveness and equity. For nurses and midwives - who play a central role in counselling, education, and community-based prevention - a clear conceptualization of adherence is essential to guide practice, research, and policy. This study aimed to analyze the concept of adherence to HPV-based cervical cancer screening and to propose an operationally useful framework for nursing and midwifery practice. A literature review of peer-reviewed studies addressing adherence to HPV-based or cervical cancer screening published between 1997 and 2025 (n = 38) was conducted using PubMed, CINAHL, and PsycINFO, and Walker and Avant's concept analysis method was applied. Adherence was defined as the extent to which eligible individuals initiate, complete, and sustain participation in recommended cervical cancer screening pathways over time in accordance with established guidelines, including appropriate timing, test modality, follow-up, and repeat screening. Defining attributes were knowledge, awareness, and empowerment; key antecedents included education and social support; and consequences encompassed improved health outcomes, fewer complications, and reduced healthcare costs. Age, gender-related factors, and healthcare professionals' counselling practices emerged as moderators influencing adherence behaviors, while anxiety, fear, and perceived lack of need acted as mediators shaping individual screening decisions. This concept analysis clarifies adherence as a complex phenomenon extending beyond a single screening event and supports the development of tailored, nurse- and midwife-led strategies to improve equitable cervical cancer prevention.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"601358"},"PeriodicalIF":2.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13142696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Feasibility and Preliminary Effects of a Stress Process Model-Based Program in Dementia Caregiving (DeCare-SPM) for Family Caregivers: A Mixed-Methods Pilot Study.","authors":"Jie Wu, Xuelian Li, Weichu Liu, Yingzhuo Ma, Qinghua Zhao, Mingzhao Xiao, Jun Wang","doi":"10.2147/JMDH.S585820","DOIUrl":"https://doi.org/10.2147/JMDH.S585820","url":null,"abstract":"<p><strong>Background: </strong>Dementia caregiving causes significant stress, making psychosocial interventions crucial. However, its success depends on effective implementation. This study aimed to evaluate the feasibility, acceptability, and preliminary effects of DeCare-SPM, a theory-driven program designed to enhance positive aspects of caregiving and reduce burden.</p><p><strong>Methods: </strong>A single-group pre-post study without a control group, using an embedded mixed-methods design, was conducted from June to July 2023. The 1-month intervention included three face-to-face sessions and four weekly telephone-based consultations. The feasibility was evaluated through recruitment rate, adherence, and satisfaction. Focus group interviews with implementers and caregivers provided qualitative insights. Preliminary effects on positive aspects of caregiving (PAC), caregiver burden, sense of competence, social network, anxiety and depression, quality of life for caregivers, and neuropsychiatric symptoms and quality of life for individuals with dementia were measured at the end of the 1-month intervention period.</p><p><strong>Results: </strong>32 caregivers were recruited; no dropouts. 81.3% (26/32) attended all sessions, and 87.5% (28/32) completed telephonic interventions. Overall satisfaction a showed a median score of 4 (P25-P75: 3.25-5), with the highest ratings for the intervention team (median 4, P25-P75: 4-4). Participation demonstrated a median score of 4 (P25-P75: 3.25-4), with particularly high engagement in reading the provided materials (median 4.5, P25-P75: 4-5). The most frequently applied strategy was seeking support from family and friends (median 4, P25-P75: 4-4). (2) Qualitative findings revealed four themes: Perceived Benefit, Peer Support, Suggestions for Improvement, and Reasons for Low Application. Post-intervention improvements were seen in PAC (t=3.553, P=0.001, d=0.63), sense of competence (t=4.673, P<0.001), social network (t=3.645, P=0.001), and EQ-5D index (t=2.785, P=0.009). Burden (t=-3.083, P=0.004, d=0.55) and anxiety (t=-3.544, P=0.001) decreased significantly.</p><p><strong>Conclusion: </strong>The DeCare-SPM was feasible and acceptable for family caregivers and showed preliminary effects on family caregivers.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"585820"},"PeriodicalIF":2.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13142733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Healthcare Professionals' Perspectives on Barriers and Facilitators in Care and Rehabilitation of Adults with Myasthenia Gravis in Neurological Departments in Denmark.","authors":"Lene Klem Olesen, Ulla Werlauff, Malene Missel, Liselotte Schirakow, Charlotte Handberg","doi":"10.2147/JMDH.S585293","DOIUrl":"https://doi.org/10.2147/JMDH.S585293","url":null,"abstract":"<p><strong>Introduction: </strong>Myasthenia gravis (MG) is a rare, chronic autoimmune disease that causes various fluctuating symptoms. Healthcare professionals at neurological departments often focus on treating MG with the risk of overlooking other aspects of daily living. Rehabilitation seeks to enable people with disabilities to become as independent as possible in everyday activities. This study aims to explore how healthcare professionals at neurological departments perceive barriers and facilitators in care and rehabilitation of adults with MG in Denmark to target future rehabilitation initiatives.</p><p><strong>Methods/materials: </strong>A qualitative design using individual interviews with healthcare professionals employed at neurological departments was performed. The qualitative interpretive description methodology aimed at informing clinical practice and the critical psychology framework by Klaus Holzkamp guided the study. Ten participants were included.</p><p><strong>Results: </strong>The results showed how \"Supporting patient understanding and navigation through personalized care\", \"Navigating responsibility and resources in clinical practice\", and \"Organizational structures impacting on professional quality of care\" were important areas for the healthcare professionals when considering barriers and facilitators to rehabilitation for their patients. The first two areas were the center of the participants' clinical practice, and surrounding and impacting on this center was the participants' perception of their ability to navigate responsibilities and resources in their clinical practice. The third area had significant impact on the quality of care, allocation of resources, and structural changes within the specialized healthcare services.</p><p><strong>Conclusion: </strong>Healthcare professionals at neurological departments experience multiple facilitators and barriers to the rehabilitation of adults with MG. Their agency potential is deeply rooted in the relational, organizational, and structural settings that they engage in. Their ability to support adults with MG in coping with their condition depends on expertise, flexibility, continuity, and interdisciplinary collaboration both in and outside their organization. It is pivotal that organizational structures support these conditions. If not, it may have negative consequences for the patients' agency potential, rehabilitation, and health.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"585293"},"PeriodicalIF":2.4,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13138321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Prediction of Successful Aging by Frailty, Functional Cognition and Well-Being in Community-Dwelling Older Adults: A Cross-Sectional Survey.","authors":"Christos Kleisiaris, Theodora Arida, Maria Klesiora, Konstantinos Tsaras, Maria Malliarou, Ioanna V Papathanasiou, Theodosios Paralikas, Nikolaos Bakalis, Mahmoud Ogla Al-Hussami, Wafa Hamad Almegewly, Savvato Karavasileiadou, Theodore D Cosco","doi":"10.2147/JMDH.S568502","DOIUrl":"https://doi.org/10.2147/JMDH.S568502","url":null,"abstract":"<p><strong>Introduction: </strong>It is widely recognised that frailty components and the functional cognition are associated with successful aging (SA). However, the true figures of this association are uncertain.</p><p><strong>Purpose: </strong>To examine the prediction of SA by frailty, functional cognition and well-being in community-dwelling adults aged 65 years and over.</p><p><strong>Patients and methods: </strong>A convenience-sampling method in a cross-sectional design was used to recruit older people who received supportive care at an \"Open Protection Centre for the Elderly\" in Crete, Greece, from March to June 2023. SA was assessed using the Successful Aging Index (SAI) and frailty using the Tilburg Frailty Indicator (TFI), well-being was assessed with the WHO-5 questionnaire, and the functional cognition was assessed with the Functional Assessment Staging Tool (FAST). To predict Successful Aging, SAI was placed as a dependent variable, and FAST staging, TFI, and WHO-5 as independent variables, including sociodemographic characteristics.</p><p><strong>Results: </strong>The mean age of the 178 participants (62.4% female) was 73.79 ± 5.41, and the frailty mean value was 6.88 ± 3.11 (range 0-15). Our sample experienced middle levels of SA (mean 54.64 ± 25.62 [range 6-95]) and well-being (mean 53.42 ± 24.66 [range 0-100]). The hierarchical linear regression model revealed that participants with physical (-2.41, p<0.001) and social frailty (-2.52, p = 0.013) are expected to present a significantly lower SA, even after adjusting for sociodemographic characteristics. Well-being was also predicted SA, suggesting that higher levels of well-being are associated with greater SA (0.27, p<0.001).</p><p><strong>Conclusion: </strong>Our findings indicate that frailty, well-being and functional cognition predicted lower SA in community-dwelling older adults, highlighting the importance of community-based interventions led by interdisciplinary teams.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"568502"},"PeriodicalIF":2.4,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13138314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive Nursing Intervention Improves Polysomnography Success, Safety, and Patient Experience in Obstructive Sleep Apnea.","authors":"Xiaodong Feng, Yuqing Miao, Chenhai Zheng, Shuai Yuan, Jie Qin","doi":"10.2147/JMDH.S576138","DOIUrl":"https://doi.org/10.2147/JMDH.S576138","url":null,"abstract":"<p><strong>Background: </strong>Polysomnography (PSG) is the gold standard for diagnosing Obstructive Sleep Apnea Syndrome (OSAS); however, monitoring failure and patient discomfort can compromise diagnostic accuracy. This study evaluated whether comprehensive nursing interventions improved PSG monitoring success, clinical parameters, and patient outcomes.</p><p><strong>Methods: </strong>This prospective observational cohort study included 100 patients with OSAS who underwent PSG. Participants were sequentially allocated to a control group (n=50) receiving standard care or an observation group (n=50) receiving comprehensive nursing intervention. The intervention integrated structured patient education, proactive technical management of monitoring equipment, cardiovascular risk assessment, and psychological support for patients. The primary outcomes were the PSG success rate and monitoring interruptions. Secondary outcomes included oxygen saturation, sleep architecture, cardiovascular events, and psychological status (anxiety and depression scores). Between-group comparisons were performed using independent <i>t</i>-tests, chi-square tests, and binary logistic regression to adjust for potential confounders.</p><p><strong>Results: </strong>The observation group demonstrated a significantly higher monitoring success rate than the control group (96.0% vs. 82.0%, P=0.025; odds ratio [OR] = 5.27, 95% CI: 1.12-24.84) and fewer monitoring interruptions (16.0% vs. 36.0%, P=0.023). The intervention group also showed significantly improved mean and lowest arterial oxygen saturation, reduced obstructive apneas and awakenings, and shortened sleep latency (all P<0.0001). No statistically significant difference was observed in the Apnea-Hypopnea Index (AHI) between the groups (P=0.312), suggesting that the intervention did not alter the underlying OSAS severity. Furthermore, the incidence of abnormal blood pressure (4.0% vs. 20.0%, P=0.014) and arrhythmia (2.0% vs. 16.0%, P=0.014) was significantly lower. Post-intervention, the observation group reported significantly lower anxiety and depression scores (P<0.0001).</p><p><strong>Conclusion: </strong>A structured nursing intervention was associated with improved PSG technical success, reduced cardiovascular events during monitoring, and better psychological well-being of patients. These findings suggest that comprehensive nursing protocols may optimize diagnostic quality in sleep medicine, although multicenter randomized controlled trials are needed to confirm causality.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"576138"},"PeriodicalIF":2.4,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13138884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mediating Effect of Depression on Relationship Between Sleep Disturbance and Locomotive Syndrome in Geriatric Cancer Patients.","authors":"Yao Chen, Hu-Nan Wang, Ying Chen, Xue-Fen Liang, Hai-Wa Xu, Rui-Rong Wu, Li-Hua Dong, Hui Su, Yu-Ling Yang","doi":"10.2147/JMDH.S594920","DOIUrl":"https://doi.org/10.2147/JMDH.S594920","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the mediating role of depression between sleep disturbance and locomotive syndrome (LS) in geriatric cancer patients, and to provide a basis for interventions targeting motor function impairment in this population.</p><p><strong>Methods: </strong>A convenience sample of 600 geriatric cancer patients was recruited in this cross-sectional study. General information questionnaires, the Pittsburgh Sleep Quality Index (PSQI), the Patient Health Questionnaire Depression Scale (PHQ-9), and the Geriatric Locomotive Function Scale (GLFS-25) were administered to measure depression, sleep disturbance, and LS. Multivariate logistic regression was used to evaluate the impact of sleep disturbance on LS. Bootstrap sampling was performed to analyze the mediating effect of depression scores this relationship.</p><p><strong>Results: </strong>Valid questionnaires were obtained from 584 geriatric cancer patients. Sleep disturbances affected 216 patients (37.0%), including 66 (11.3%) with moderate-to-severe disturbances, while 259 (44.3%) had LS. After controlling for confounding factors, multivariate logistic regression showed that geriatric cancer patients with mild and moderate-to-severe sleep disturbances had 1.42-fold (95% <i>CI</i>: 1.23~1.67, <i>P</i>=0.001) and 1.81-fold (95% <i>CI</i>: 1.31~2.45, <i>P</i><0.001) higher risks of LS, respectively. Mediator analysis revealed that depression partially mediated the relationship between sleep disturbances and LS, with an effect size of 0.043 (95% <i>CI</i>: 0.032~0.055, <i>P</i><0.001), accounting for 21.15% of the total effect.</p><p><strong>Conclusion: </strong>Depression, sleep disturbance, and LS are closely related. Sleep disturbance was directly and indirectly associated with LS through depression. Healthcare providers should pay attention to sleep disturbances and depression in geriatric cancer patients. For patients whose sleep quality cannot be effectively improved, alleviating depressive symptoms may help reduce the incidence of LS.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"594920"},"PeriodicalIF":2.4,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13135895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of the Average Recommendation Time for the Incorporation of Biological Drugs for Cancer and Rheumatoid Arthritis.","authors":"Marcio Santos da Natividade, Erick Soares Lisboa, Erika Aragão, Caroline Tianeze de Castro, Rafael Damasceno de Barros, Marcos Pereira, Samilly Silva Miranda, Luís Eugênio Souza, Naomar de Almeida-Filho","doi":"10.2147/JMDH.S532154","DOIUrl":"https://doi.org/10.2147/JMDH.S532154","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the average time between the registration of a biological drug and its recommendation for incorporation for rheumatoid arthritis (RA) and cancer (CA) at national and international levels.</p><p><strong>Methods: </strong>This retrospective, comparative study analyzed the time taken to incorporate biological drugs recommended by National Commission for the Incorporation of Technologies (CONITEC) in the Brazilian Unified Health System(SUS) for RA and CA from January 1, 2012, to March 28, 2024. The incorporation time in Brazil was compared to that of regulatory bodies in England and Australia for the same treatments. Kaplan-Meier curves and the Log rank test were used to estimate time differences between countries.</p><p><strong>Results: </strong>In Brazil, biological drugs for RA took an average of 2,019 days from the National Health Surveillance Agency (ANVISA) approval to CONITEC's incorporation recommendation. In England, the averages were 1,242 days for RA and 1,683 for CA, while in Australia, it was 744 days for RA and 1,315 for CA. Australia incorporated drugs faster than both England and Brazil.</p><p><strong>Conclusion: </strong>The lengthy process in Brazil for incorporating biological technologies for RA and CA may hinder access, delaying treatment for many patients. This barrier is particularly significant for low-income individuals who rely exclusively on the SUS.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"532154"},"PeriodicalIF":2.4,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13136709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating Artificial Intelligence into Clinical Care: A Cross-Sectional Study to Advance Healthcare in Saudi Arabia.","authors":"Maryam Allayl, Ghareeb Bahari","doi":"10.2147/JMDH.S598736","DOIUrl":"https://doi.org/10.2147/JMDH.S598736","url":null,"abstract":"<p><strong>Purpose: </strong>Mounting evidence suggests that artificial intelligence can support the self-management of chronic diseases, including skin conditions, insulin management, and blood pressure control. This study aimed to investigate the potential use of artificial intelligence (AI) in chronic condition management among patients in Saudi Arabia, where the prevalence of such diseases is increasing. Specifically, we assessed AI perception, self-efficacy, and cognitive symptom management; examined their associations with demographic variables, and evaluated the influence of AI perception and self-efficacy on cognitive symptom management.</p><p><strong>Patients and methods: </strong>This study employed a cross-sectional, descriptive-correlational design. Data were collected at a single time point to characterize the sample and explore relationships among variables. A convenience sample of 163 patients with chronic conditions was recruited. A structured questionnaire was used to assess AI perception, self-efficacy, cognitive symptom management, and demographic characteristics. Data were collected between December 2024 and March 2025 and were analyzed using descriptive statistics, Pearson's correlation coefficient, one-way analysis of variance, and multiple regression analysis, as appropriate.</p><p><strong>Results: </strong>The findings revealed that sex significantly influenced AI awareness, indicating a need for targeted outreach, particularly for women who demonstrated lower levels of AI awareness. Additionally, self-efficacy was a significant predictor of better cognitive symptom management (p < 0.01), as participants with higher self-efficacy reported significantly better management of cognitive symptoms and greater engagement in health-promoting behaviors compared to those with lower self-efficacy.</p><p><strong>Conclusion: </strong>Our results highlight that self-efficacy is a key factor in managing cognitive symptoms associated with chronic conditions and underscore the importance of targeted interventions to enhance inclusivity and strengthen individuals' confidence in managing their health. These findings can also inform the development of healthcare programs aimed at empowering patient self-management through AI-based tools.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"19 ","pages":"598736"},"PeriodicalIF":2.4,"publicationDate":"2026-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13127431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147816291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}