Journal of Multidisciplinary Healthcare最新文献

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Video Quality Assessment and Analysis of Gastroesophageal Reflux Disease on TikTok and Bilibili: Cross-Sectional Study.
IF 2.7 3区 医学
Journal of Multidisciplinary Healthcare Pub Date : 2024-12-11 eCollection Date: 2024-01-01 DOI: 10.2147/JMDH.S485781
Ying Liang, Jianlei Xia, Wenting Huo, Bangjie Liu, Zhangyu Wang, Yanbing Ding, Keyan Wu
{"title":"Video Quality Assessment and Analysis of Gastroesophageal Reflux Disease on TikTok and Bilibili: Cross-Sectional Study.","authors":"Ying Liang, Jianlei Xia, Wenting Huo, Bangjie Liu, Zhangyu Wang, Yanbing Ding, Keyan Wu","doi":"10.2147/JMDH.S485781","DOIUrl":"https://doi.org/10.2147/JMDH.S485781","url":null,"abstract":"<p><strong>Aims and objectives: </strong>To assess the content quality and reliability of Gastroesophageal reflux disease (GERD) videos on TikTok and Bilibili.</p><p><strong>Background: </strong>Since many people with GERD use current online platforms to search for health information, there is a need to assess the quality of GERD videos on social media. There are many GERD videos on TikTok and Bilibili; however, the quality of information in these videos remains unknown.</p><p><strong>Design: </strong>A cross-sectional survey on two video platforms.</p><p><strong>Methods: </strong>In November 2023, we retrieved 200 videos from TikTok and Bilibili with the search term \"GERD.\" Basic video information was extracted, the content coded, and the video source identified. Two independent raters assessed the quality of each video using the Journal of the American Medical Association (JAMA) benchmark criteria, the modified DISCERN (mDISCERN) criteria, and the Global Quality Score (GQS) tool.</p><p><strong>Results: </strong>A total of 156 videos were collected. Most of the videos on TikTok and Bilibili came from gastroenterologists. TikTok's GERD video quality and reliability were higher than Bilibili's. The mDISCERN and GQS scores of both platforms were positively correlated with duration, and the GQS score was positively correlated with collection and shares. Bilibili's JAMA score was negatively correlated with time-sync comments, and TikTok's JAMA score was negatively correlated with days since upload.</p><p><strong>Conclusion: </strong>This study indicated that the content quality scores of TikTok and Bilibili as sources of scientific information on GERD are average, and patients should carefully identify and select to watch GERD-related videos on TikTok and Bilibili.</p><p><strong>Relevance to clinical practice: </strong>By evaluating the quality of videos on GERD on the two platforms, this can provide new ideas for health education interventions in the clinic and a relevant basis for improving the quality level of the videos.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5927-5939"},"PeriodicalIF":2.7,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11646458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bibliometric Analysis of Comprehensive Geriatric Assessment from 2004 to 2023.
IF 2.7 3区 医学
Journal of Multidisciplinary Healthcare Pub Date : 2024-12-10 eCollection Date: 2024-01-01 DOI: 10.2147/JMDH.S488030
Fan Zhang, Yujun Xiong, Xiangda Meng, Huazhao Xu, Qiuli Zhang
{"title":"Bibliometric Analysis of Comprehensive Geriatric Assessment from 2004 to 2023.","authors":"Fan Zhang, Yujun Xiong, Xiangda Meng, Huazhao Xu, Qiuli Zhang","doi":"10.2147/JMDH.S488030","DOIUrl":"https://doi.org/10.2147/JMDH.S488030","url":null,"abstract":"<p><strong>Background: </strong>The global aging population necessitates specialized tools for complex geriatric health issues. Comprehensive Geriatric Assessment (CGA) provides multidimensional evaluations of elderly, integrating inputs from various professionals to create individualized care plans. This study aims to visually assess the research trends and hotspots in the field of CGA, review mainstream perspectives in this field, and provide a foundation for future research and treatment.</p><p><strong>Methods: </strong>Original and review articles related to comprehensive geriatric assessment, published from 2004 to December 2023, were extracted from the Web of Science database. Four different software tools-CiteSpace, VOSviewer, Bibliometrix R package, and the Online Analysis Platform of Bibliometrics-were utilized for this comprehensive analysis.</p><p><strong>Results: </strong>According to our retrieval strategy, we found a total of 4,411 related literatures. There has been a substantial increase in the research on comprehensive geriatric assessment in the past 20 years. These publications have been cited 157,366 times, with a mean of 35.68 citations per publication. The largest number of publications were from the US, and Italy ranked second (14.98%). Keyword burst and concurrence showed that \"randomized trial\", \"adjuvant chemotherapy\" and \"breast cancer\" were the top 3 most frequently occurring keywords.</p><p><strong>Conclusion: </strong>Our bibliometric analysis reveals significant growth in CGA research over the past two decades, with a shift from cancer-focused studies to chronic conditions like frailty and sarcopenia. These findings highlight evolving priorities in geriatric care and underscore the need for future research to integrate technological advancements, such as AI, to enhance the precision, scalability, and cost-effectiveness of CGA in diverse settings.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5901-5915"},"PeriodicalIF":2.7,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11645894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Consumption of Sugar-Sweetened Beverages in People with Severe Mental Illness: A Community-Based Cohort Study.
IF 2.7 3区 医学
Journal of Multidisciplinary Healthcare Pub Date : 2024-12-10 eCollection Date: 2024-01-01 DOI: 10.2147/JMDH.S479281
Tim J Lambert, Maryam Jay, Erikka Hennessy, Kathleen Smith, Premala Sureshkumar
{"title":"Consumption of Sugar-Sweetened Beverages in People with Severe Mental Illness: A Community-Based Cohort Study.","authors":"Tim J Lambert, Maryam Jay, Erikka Hennessy, Kathleen Smith, Premala Sureshkumar","doi":"10.2147/JMDH.S479281","DOIUrl":"https://doi.org/10.2147/JMDH.S479281","url":null,"abstract":"<p><strong>Objective: </strong>Excess mortality in mentally ill is largely due to high rates of physical illnesses that lead to worse health outcomes. This study examines the intake of added sugar from sugar-sweetened beverages (SSBs) and factors associated with poor mental and physical health in people with severe mental illness.</p><p><strong>Methods: </strong>Data were collected as part of the standard care of consumers attending the Collaborative Centre for Cardiometabolic Health in Psychosis clinics where a diet history is taken by a dietitian. SSBs and tea/coffee with added sugars consumed in the past seven days were collected.</p><p><strong>Results: </strong>Overall, 1648 occasions of service comprising 1142 consumers (mean age 45.0 ± 12.5 years, 63.5% males) were seen. Of these, 1234 (74.9%) occasions of service were provided by a dietitian. Two-thirds (n = 840) self-reported to have consumed one or more SSBs or tea/coffee with sugar. Over half 697 (56.5%) consumed one or more SSBs and 437 (35.4%) tea/coffee with sugar. The mean daily consumption of added sugar from SSBs and tea/coffee was 86.2 g/day. On multivariable analysis, males, those diagnosed with schizophrenia, being on Olanzapine ± other antipsychotics and lower socio-economic status were statistically associated with consumption of added sugar.</p><p><strong>Conclusion: </strong>Consumption of added sugars from SSBs in consumers of community mental health services is four times higher than the general population. This is an underestimation of the total intake of added sugars without other contributors from discretionary foods. Measuring consumption of SSBs may be an easy-to-use proxy for assessing dietary risk when dietitians are not available.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5887-5899"},"PeriodicalIF":2.7,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11645958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical-Radiomics Nomogram Model Based on CT Angiography for Prediction of Intracranial Aneurysm Rupture: A Multicenter Study.
IF 2.7 3区 医学
Journal of Multidisciplinary Healthcare Pub Date : 2024-12-10 eCollection Date: 2024-01-01 DOI: 10.2147/JMDH.S491697
Xiu-Fen Jia, Yong-Chun Chen, Kui-Kui Zheng, Dong-Qin Zhu, Chao Chen, Jinjin Liu, Yun-Jun Yang, Chuan-Ting Li
{"title":"Clinical-Radiomics Nomogram Model Based on CT Angiography for Prediction of Intracranial Aneurysm Rupture: A Multicenter Study.","authors":"Xiu-Fen Jia, Yong-Chun Chen, Kui-Kui Zheng, Dong-Qin Zhu, Chao Chen, Jinjin Liu, Yun-Jun Yang, Chuan-Ting Li","doi":"10.2147/JMDH.S491697","DOIUrl":"https://doi.org/10.2147/JMDH.S491697","url":null,"abstract":"<p><strong>Objective: </strong>Risk estimation of intracranial aneurysm rupture is critical in determining treatment strategy. There is a scarcity of multicenter studies on the predictive power of clinical-radiomics models for aneurysm rupture. This study aims to develop a clinical-radiomics model and explore its additional value in the discrimination of aneurysm rupture.</p><p><strong>Methods: </strong>A total of 516 aneurysms, including 273 (52.9%) with ruptured aneurysms, were retrospectively enrolled from four hospitals between January 2019 and August 2020. Relevant clinical features were collected, and radiomic characteristics associated with aneurysm were extracted. Subsequently, three models, including a clinical model, a radiomics model, and a clinical-radiomics model were constructed using multivariate logistic regression analysis to effectively classify aneurysm rupture. The performance of models was analyzed through operating characteristic curves, decision curve, and calibration curves analysis. Different models' comparison used DeLong tests. To offer an understandable and intuitive scoring system for assessing rupture risk, we developed a comprehensive nomogram based on the developed model.</p><p><strong>Results: </strong>Three clinical risk factors and fourteen radiomics features were explored to establish three models. The area under the receiver operating curve (AUC) for the radiomics model was 0.775 (95% CI,0.719-0.830), 0.752 (95% CI,0.663-0.841), 0.747 (95% CI,0.658-0.835) in the training, internal and external test datasets, respectively. The AUC for clinical model was 0.802 (95% CI, 0.749-0.854), 0.736 (95% CI, 0.644-0.828), 0.789 (95% CI, 0.709-0.870) in these three sets, respectively. The clinical-radiomics model showed an AUC of 0.880 (95% CI,0.840-0.920), 0.807 (95% CI,0.728-0.887), 0.815 (95% CI,0.740-0.891) in three datasets respectively. Compared with the radiomics and clinical models, the clinical-radiomics model demonstrated better diagnostic performance (DeLong' test P < 0.05).</p><p><strong>Conclusion: </strong>The clinical-radiomics model represents a promising approach for predicting rupture of intracranial aneurysms.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5917-5926"},"PeriodicalIF":2.7,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11645942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exercise Interventions in the Management of Postural Orthostatic Tachycardia Syndrome: A Scoping Review.
IF 2.7 3区 医学
Journal of Multidisciplinary Healthcare Pub Date : 2024-12-09 eCollection Date: 2024-01-01 DOI: 10.2147/JMDH.S495088
Patricia Gonçalves Leite Rocco, C Mahony Reategui-Rivera, Joseph Finkelstein
{"title":"Exercise Interventions in the Management of Postural Orthostatic Tachycardia Syndrome: A Scoping Review.","authors":"Patricia Gonçalves Leite Rocco, C Mahony Reategui-Rivera, Joseph Finkelstein","doi":"10.2147/JMDH.S495088","DOIUrl":"https://doi.org/10.2147/JMDH.S495088","url":null,"abstract":"<p><strong>Objective: </strong>This review aims to identify the exercise rehabilitation approaches used for patients with POTS (Postural Orthostatic Tachycardia Syndrome).</p><p><strong>Methods: </strong>An electronic literature search was conducted using the PubMed database, covering January 2005 to October 2023. Studies were included if they reported an exercise rehabilitation intervention for POTS patients and resulting clinical outcomes. Eligible study designs included randomized and non-randomized clinical trials and case reports.</p><p><strong>Results: </strong>Initially, 34 publications were identified, but only 14 met the criteria for inclusion. After a thorough analysis, 7 studies were included in this scoping review. The majority of the studies stated aerobic exercise training significantly improves symptoms in most of the patients with orthostatic intolerance, reduces the frequency of syncope, enhances patient quality of life, and improves autonomic balance as assessed by heart rate variability analysis and cardiorespiratory endurance. Short-term exercise training was found to boost physical fitness and cardiorespiratory responses in patients with POTS. Therefore, exercise training can serve as an effective non-pharmacological therapy for managing POTS.</p><p><strong>Conclusion: </strong>This scoping review identified different approaches used for exercise rehabilitation in POTS patients. However, more research is needed to identify the optimal exercise rehabilitation program for this patient population.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5867-5885"},"PeriodicalIF":2.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11646465/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes and Risk Factors in Patients with Hematologic Malignancies Following Late-Stage SARS-CoV-2 Infection.
IF 2.7 3区 医学
Journal of Multidisciplinary Healthcare Pub Date : 2024-12-08 eCollection Date: 2024-01-01 DOI: 10.2147/JMDH.S491098
Lina Wang, Jiang Liu, Yafang Guo, Meiling Zhao, Bozheng Zhang, Junyan Zhang, Ruijuan Zhang
{"title":"Outcomes and Risk Factors in Patients with Hematologic Malignancies Following Late-Stage SARS-CoV-2 Infection.","authors":"Lina Wang, Jiang Liu, Yafang Guo, Meiling Zhao, Bozheng Zhang, Junyan Zhang, Ruijuan Zhang","doi":"10.2147/JMDH.S491098","DOIUrl":"10.2147/JMDH.S491098","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the outcomes and risk factors for patients with hematologic malignancies (HM) following late-stage SARS-CoV-2 infection.</p><p><strong>Background: </strong>Patients with HM such as lymphoproliferative malignancies (including acute lymphoblastic leukemia and multiple myeloma) and myeloproliferative malignancies (including acute myeloid leukemia, myeloproliferative neoplasm, and myelodysplastic syndrome) are at increased risk of severe illness and high mortality from COVID-19. This study examines the impact of SARS-CoV-2 infection severity on HM prognosis during the late phase of COVID-19, using data from 203 patients at Shanxi Bethune Hospital.</p><p><strong>Methods: </strong>This is a retrospective cohort study. Data was collected from hospitalized HM patients at a single center from December 1, 2023, to December 31, 2023. The primary outcome was overall survival (OS). Multivariable Cox regression was used to identify risk factors.</p><p><strong>Results: </strong>This analysis includes data from 203 hospitalized patients with HM aged 36 to 67 years (median, 58 years). SARS-CoV-2 infection was observed in 42.86% (87/203) of the patients, among whom severe/critical cases accounted for 14.29% (29/203). Multivariable Cox regression shows active disease (hazard ratio [HR] 2.16, 95% confidence interval [CI] 1.00-4.64, p = 0.049), hematopoietic stem cell transplantation (HSCT) (HR 4.06, 95% CI 1.02-16.12, p = 0.047), and targeted therapy (HR 2.60, 95% CI 1.23-5.50, p = 0.012) were associated with a higher incidence of progression. In contrast, individuals whose platelets count ≥50×10<sup>9</sup>/L at baseline (HR = 0.36, 95% CI 0.17-0.78, p = 0.009) and ferritin levels less than 500 µg/L (HR = 0.54, 95% CI 0.34-0.86, p = 0.010) were associated with a lower incidence of progression. Active status (HR 7.06, 95% CI 2.10-23.76, p = 0.002), HSCT (HR 7.17, 95% CI 1.10-46.63, p = 0.039), and severe/critical SARS-CoV-2 infection in HM patients (HR 11.98, 95% CI 2.57-55.82, p = 0.002) were associated with higher incidences of all cause of mortality. While a higher platelet level (≥50×10<sup>9</sup>/L) was linked to a lower mortality (HR 0.16, 95% CI 0.05-0.49, p = 0.002).</p><p><strong>Conclusion: </strong>In the late stage of the COVID-19 pandemic, active disease status, recent HSCT, and severe/critical SARS-CoV-2 infection significantly increased the risks of disease progression and mortality in HM patients. Higher baseline platelet counts were associated with improved outcomes.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5853-5865"},"PeriodicalIF":2.7,"publicationDate":"2024-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11636247/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Systematic Scoping Review of Essential Methodological Elements for Developing a Tool to Improve the Reporting of Consensus Studies in Classification, Diagnostic Criteria, and Guidelines Development.
IF 2.7 3区 医学
Journal of Multidisciplinary Healthcare Pub Date : 2024-12-08 eCollection Date: 2024-01-01 DOI: 10.2147/JMDH.S484715
Yimy F Medina, Cindy V Mendieta, Natalia Prieto, María Laura Acosta Felquer, Enrique R Soriano
{"title":"A Systematic Scoping Review of Essential Methodological Elements for Developing a Tool to Improve the Reporting of Consensus Studies in Classification, Diagnostic Criteria, and Guidelines Development.","authors":"Yimy F Medina, Cindy V Mendieta, Natalia Prieto, María Laura Acosta Felquer, Enrique R Soriano","doi":"10.2147/JMDH.S484715","DOIUrl":"10.2147/JMDH.S484715","url":null,"abstract":"<p><strong>Introduction: </strong>A consensus is a general agreement among group members that is pivotal in gathering expert input for classification, diagnostic criteria, and guideline development. However, the absence of established methodological standards presents challenges in conducting and analyzing these studies.</p><p><strong>Objective: </strong>This scoping review explored the evidence on essential elements in consensus studies to create a list of candidate items for a standardized reporting tool. This tool is intended to improve the critical appraisal and methodological rigor of consensus studies.</p><p><strong>Methods: </strong>A systematic scoping review was conducted using predetermined criteria for study selecting studies and extracting data. A comprehensive literature search was performed without imposing date restrictions, covering multiple databases, including Medline, Embase, LILACS, SciELO, and up to March 2022. We included only English-language publications and excluded incomplete articles and conference reports. The risk of bias was assessed using the CASP checklist, and the study selection and data extraction were performed independently by two researchers in duplicate.</p><p><strong>Results: </strong>We identified 8360 references; 20 publications were included for data extraction. The majority (70%) used the Delphi method, and the remainder (30%) employed the modified Delphi method. Inconsistencies in reporting conflicts of interest and consensus timing were observed. Other methodologies, such as RAND/UCLA and Nominal Group Technique were excluded due to methodological limitations. Most studies exhibited a low risk of bias.</p><p><strong>Discussion: </strong>Our findings underscored the need for more standardization in definitions, methodology, and reporting within consensus studies. To address these gaps, we developed a checklist of key reporting items aimed at improving the planning, execution, and reporting consensus studies. Although the developed checklist requires validation, it offers a practical framework to enhance methodological transparency and reliability.</p><p><strong>Conclusion: </strong>Deficiencies and variability in consensus methodologies reporting underscore the need for a standardized approach. We propose the adoption of a checklist to strengthen the robustness of consensus studies, supporting advances in classification, diagnostic criteria, and guideline development.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5813-5830"},"PeriodicalIF":2.7,"publicationDate":"2024-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11636244/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification of a Missense Mutation in the FLNC Gene from a Chinese Family with Restrictive Cardiomyopathy [Letter].
IF 2.7 3区 医学
Journal of Multidisciplinary Healthcare Pub Date : 2024-12-07 eCollection Date: 2024-01-01 DOI: 10.2147/JMDH.S508083
Hasta Handayani Idrus
{"title":"Identification of a Missense Mutation in the FLNC Gene from a Chinese Family with Restrictive Cardiomyopathy [Letter].","authors":"Hasta Handayani Idrus","doi":"10.2147/JMDH.S508083","DOIUrl":"10.2147/JMDH.S508083","url":null,"abstract":"","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5811-5812"},"PeriodicalIF":2.7,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11633306/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep-Learning-Based Radiomics to Predict Surgical Risk Factors for Lumbar Disc Herniation in Young Patients: A Multicenter Study.
IF 2.7 3区 医学
Journal of Multidisciplinary Healthcare Pub Date : 2024-12-07 eCollection Date: 2024-01-01 DOI: 10.2147/JMDH.S493302
Zheng Fan, Tong Wu, Yang Wang, Zhuoru Jin, Tong Wang, Da Liu
{"title":"Deep-Learning-Based Radiomics to Predict Surgical Risk Factors for Lumbar Disc Herniation in Young Patients: A Multicenter Study.","authors":"Zheng Fan, Tong Wu, Yang Wang, Zhuoru Jin, Tong Wang, Da Liu","doi":"10.2147/JMDH.S493302","DOIUrl":"10.2147/JMDH.S493302","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study is to develop and validate a deep-learning radiomics model for predicting surgical risk factors for lumbar disc herniation (LDH) in young patients to assist clinicians in identifying surgical candidates, alleviating symptoms, and improving prognosis.</p><p><strong>Methods: </strong>A retrospective analysis of patients from two medical centers was conducted. From sagittal and axial MR images, the regions of interest were handcrafted to extract radiomics features. Various machine-learning algorithms were employed and combined with clinical features, resulting in the development of a deep-learning radiomics nomogram (DLRN) to predict surgical risk factors for LDH in young adults. The efficacy of the different models and the clinical benefits of the model were compared.</p><p><strong>Results: </strong>We derived six sets of features, including clinical features, radiomics features (Rad_SAG and Rad_AXI) and deep learning features (DL_SAG and DL_AXI) from sagittal and axial MR images, as well as fused deep-learning radiomics (DLR) features. The support vector machine(SVM) algorithm exhibited the best performance. The area under the curve (AUC) of DLR in the training and testing cohorts of 0.991 and 0.939, respectively, were significantly better than those of the models developed with radiomics(Rad_SAG=0.914 and 0.863, Rad_AXI=0.927 and 0.85) and deep-learning features(DL_SAG=0.959 and 0.818, DL_AXI=0.960 and 0.811). The AUC of DLRN coupled with clinical features(ODI, Pfirrmann grade, SLRT, MMFI, and MSU classification) were 0.994 and 0.941 in the training and testing cohorts, respectively. Analysis of the calibration and decision curves demonstrated good agreement between the predicted and observed outcomes, and the use of the DLRN to predict the need for surgical treatment of LDH demonstrated significant clinical benefits.</p><p><strong>Conclusion: </strong>The DLRN established based on clinical and DLR features effectively predicts surgical risk factors for LDH in young adults, offering valuable insights for diagnosis and treatment.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5831-5851"},"PeriodicalIF":2.7,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11633295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Latent Profile Analysis and Determinants of Marital Adjustment in Patients with Breast Cancer.
IF 2.7 3区 医学
Journal of Multidisciplinary Healthcare Pub Date : 2024-12-05 eCollection Date: 2024-01-01 DOI: 10.2147/JMDH.S494987
Xiao-Feng Chen, Chen Shen, Zhi-Feng Gu, Chen Dong, Yuan Zhuang, Li-Hua Lu, Ping Lu, Yi-Ju Li
{"title":"Latent Profile Analysis and Determinants of Marital Adjustment in Patients with Breast Cancer.","authors":"Xiao-Feng Chen, Chen Shen, Zhi-Feng Gu, Chen Dong, Yuan Zhuang, Li-Hua Lu, Ping Lu, Yi-Ju Li","doi":"10.2147/JMDH.S494987","DOIUrl":"10.2147/JMDH.S494987","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study is to assess the latent profile types of marital adjustment in patients with breast cancer and to analyze the factors influencing these various profiles.</p><p><strong>Methods: </strong>Patients with breast cancer who visited the Breast Surgery Department from January to June 2023 were selected using convenience sampling. These patients were surveyed using a general data questionnaire, the Revised Dyadic Adjustment Scale (RDAS), the Interpersonal Reactivity Index-C (IRI-C), and the Emotional Regulation Self-Efficacy Scale (RESS). Latent profile analysis (LPA) was used to determine different types of marital adjustment among patients, and influencing factors for the various profiles were identified through univariate analysis and multivariate logistic regression analysis.</p><p><strong>Results: </strong>Marital adjustment in patients with breast cancer was categorized into three latent profiles: the \"low marital adjustment-low cohesion group\" (20.2%), the \"midlevel marital adjustment group\" (35.3%), and the \"high marital adjustment-satisfaction group\" (44.4%). The influencing factors included age, marital status, primary caregiver, type of surgical intervention, empathy, and emotional regulation self-efficacy (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>The marital adjustment levels of patients with breast cancer exhibited significant heterogeneity. Medical staff can implement targeted interventions based on the distinct characteristics of each marital adjustment profile, thereby enhancing the marital adjustment of these patients.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5799-5809"},"PeriodicalIF":2.7,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11627107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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