Journal of Multidisciplinary Healthcare最新文献

{"title":"Higher Post-Acute Health Care Costs Following SARS-CoV-2 Infection Among Adults in Ontario, Canada.","authors":"Candace D McNaughton, Peter C Austin, Zhiyin Li, Atul Sivaswamy, Jiming Fang, Husam Abdel-Qadir, Jacob A Udell, Walter P Wodchis, Douglas S Lee, Ivona Mostarac, Clare L Atzema","doi":"10.2147/JMDH.S465154","DOIUrl":"10.2147/JMDH.S465154","url":null,"abstract":"<p><strong>Purpose and introduction: </strong>Growing evidence suggests SARS-CoV-2 infection increases the risk of long term cardiovascular, neurological, and other effects. However, post-acute health care costs following SARS-CoV-2 infection are not known.</p><p><strong>Patients and statistical methods: </strong>Beginning 56 days following SARS-CoV-2 polymerase chain reaction (PCR) testing, we compared person-specific total and component health care costs (2020 CAD$) for the first year of follow-up at the mean and 99^th percentiles of health care costs for matched test-positive and test-negative adults in Ontario, Canada, between January 1, 2020, and March 31, 2021. Matching included demographics, baseline clinical characteristics, and two-week time blocks.</p><p><strong>Results: </strong>For 531,182 people, mean person-specific total health care costs were $513.83 (95% CI $387.37-$638.40) higher for test-positive females and $459.10 (95% CI $304.60-$615.32) higher for test-positive males, which were driven by hospitalization, long-term care, and complex continuing care costs. At the 99^th percentile of each subgroup, person-specific health care costs were $12,533.00 (95% CI $9008.50-$16,473.00) higher for test-positive females and $14,604.00 (95% CI $9565.50-$19,506.50) for test-positive males, driven by hospitalization, specialist (males), and homecare costs (females). Cancer costs were lower. Six-month and 1-year cost differences were similar.</p><p><strong>Conclusion: </strong>Post-acute health care costs after a positive SARS-CoV-2 PCR test were significantly higher than matched test-negative individuals, and these increased costs persisted for at least one year. The largest increases health care costs came from hospitalizations, long-term care, complex continuing care, followed by outpatient specialists (for males) and homecare costs (for women). Given the magnitude of ongoing viral spread, policymakers, clinicians, and patients should be aware of higher post-acute health care costs following SARS-CoV-2 infection.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5749-5761"},"PeriodicalIF":2.7,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11628314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Work Reward Moderates the Association Between Work Effect and Workplace Violence Among Medical Staff in China.","authors":"Yifu Zhao, Aichen Zhang, Wen Zhang, Long Sun","doi":"10.2147/JMDH.S495514","DOIUrl":"10.2147/JMDH.S495514","url":null,"abstract":"<p><strong>Purpose: </strong>Workplace violence (WPV) against healthcare workers is a significant public health issue in China and globally. Although the effort-reward imbalance theory claimed that work rewards may moderate the relationship between work effort and WPV, the quantitative evidence is limited. This study aimed to examine if work reward could moderate the associations between work effort and WPV against medical staff based on the effort-reward imbalance theory.</p><p><strong>Methods: </strong>This is a cross-sectional study, which was conducted in 12 hospitals in Shandong, China. Data collected from 3426 medical staff were analyzed in this study. Work effort was evaluated by working hours and night shift work times per month (NSWM), and work reward was evaluated by monthly income and perceived social status. WPV, occupational characteristics, physical disease, and social-demographic variables were also evaluated in this study.</p><p><strong>Results: </strong>There were 1788 (52.2%) medical staff, who reported the experience of workplace violence. Working hours, NSWM, and perceived social status were associated with WPV (all <i>p</i><0.001). Monthly income could moderate the associations between monthly income and WPV or verbal violence (<i>p</i><0.05), and perceived social status could moderate the associations between NSWM and WPV (<i>p</i><0.001).</p><p><strong>Conclusion: </strong>Monthly income could moderate the associations between monthly income and WPV (verbal violence), and perceived social status could moderate the associations between NSWM and WPV, which could be explained by the effort-reward imbalance model. These findings also can be translated into practices to control WPV against medical staff.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5763-5774"},"PeriodicalIF":2.7,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11626205/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebral Microbleeds and Antiplatelet Therapy in Mongolian and Han Patients with Ischemic Cerebrovascular Disease.","authors":"Haichao Fu, Lihong Ge, Junguo Liang","doi":"10.2147/JMDH.S491665","DOIUrl":"10.2147/JMDH.S491665","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the differences in cerebral microbleeds (CMBs) and their correlation with intracerebral hemorrhage (ICH) in Mongolian and Han Chinese patients with ischemic cerebrovascular disease.</p><p><strong>Methods: </strong>A total of 160 patients with ischemic cerebrovascular disease who took aspirin or clopidogrel for over one year were retrospectively analyzed, including 80 Mongolian and 80 han patients. The incidence, number, and distribution of CMBs were compared between groups. Logistic regression was used to identify risk factors for the occurrence of cerebral hemorrhage.</p><p><strong>Results: </strong>The detection rate of CMBs was significantly lower in Mongolian patients compared to Han patients (P = 0.040). Mongolian patients had a higher distribution of CMBs in the deep or infratentorial regions (66.6% vs 58.1%), while Han patients had a higher lobar distribution (P = 0.007). Prolonged antiplatelet therapy (over 3 years) was a risk factor for CMB development in both groups and was also linked to an increased risk of ICH. Patients with a higher number of CMBs had a greater likelihood of experiencing ICH.</p><p><strong>Conclusion: </strong>Mongolian patients had a lower likelihood of developing CMBs than Han patients, but with a higher deep or infratentorial distribution. The presence of CMBs, especially with long-term antiplatelet therapy, is a significant predictor of ICH. No significant difference in ICH risk was found between ethnic groups. Close monitoring of patients with CMBs during prolonged antiplatelet therapy is crucial to reduce hemorrhagic events.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5789-5798"},"PeriodicalIF":2.7,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11625424/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Analysis of the Efficacy of the Health Butler Application and Intelligent Accompaniment Systems in Smart Outpatient Services Based on Patient Feedback.","authors":"Bing Xiao, Li-Ping Zhang, Cheng Feng, Ling-Xiang Meng, Wan-Qi Yu, Min Zou","doi":"10.2147/JMDH.S489515","DOIUrl":"10.2147/JMDH.S489515","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to explore the efficacy of a smart outpatient service system incorporating the Health Butler application and Intelligent Accompaniment based on patients' feedback.</p><p><strong>Methods: </strong>A total of 1000 outpatients from Shenzhen Third People's Hospital were randomly selected in May 2023 and November 2023 to provide feedback before and after implementing the smart outpatient service system consisting of the Health Butler app and Intelligent Accompaniment. The changes in the patient's awareness of the medical treatment process, average waiting time, satisfaction with the experience of seeking medical treatment, and trust in medical services offered based on patient feedback were compared pre- and post-implementation.</p><p><strong>Results: </strong>There were significant differences in outpatients' awareness of the process of medical treatment, average waiting time, satisfaction with the experience of seeking medical care, and trust in medical services before and after the implementation of the smart outpatient service system (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>The smart outpatient service system, which incorporated the Health Butler app and Intelligent accompaniment based on patient feedback, was effective in improving awareness of the process of medical treatment among outpatients, shortening their average waiting time, improving patient satisfaction with the experience of seeking medical care, and also enhancing their trust in medical services.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5775-5787"},"PeriodicalIF":2.7,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11625635/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Involvement of Urease-Producing Bacteria on Genital Skin in Community-Dwelling Women with Incontinence-Associated Dermatitis: A Cross-Sectional Study.","authors":"Masushi Kohta, Junko Sugama","doi":"10.2147/JMDH.S492458","DOIUrl":"10.2147/JMDH.S492458","url":null,"abstract":"<p><strong>Purpose: </strong>Elevated skin pH facilitates the number of pathogenic bacteria increase, leading to the skin barrier dysfunction. This phenomenon is typically observed in individuals with Incontinence-associated dermatitis (IAD), which imposes a substantial physical and psychological burden on the afflicted individuals. We evaluated the association between the development of IAD in community-dwelling women with urinary incontinence and cutaneous urease-producing bacteria, as these bacteria may be involved in elevating skin pH by chemical reaction with urea in urine.</p><p><strong>Patients and methods: </strong>This was a cross-sectional study of 114 community-dwelling women with urinary incontinence who had registered for a survey campaign of a company. Swabs collected from genital skin were cultured in urea agar medium. The presence of urease-producing bacteria was determined by visually observing the change in the color of the culture medium caused by alkalization. The medium pH and total bacteria count were measured. Bacterial species were isolated and identified using a selective agar medium and simple identification kits. The participants were asked the presence of IAD by a self-administered questionnaire, and outcomes were compared between the IAD and no-IAD groups. This study followed the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guideline.</p><p><strong>Results: </strong>IAD was present in 31.6% (36/114) of participants. The detection rate of urease-producing bacteria and the medium pH was significantly higher in the IAD group than in the no-IAD group; however, the total number of bacteria was not significantly different. There were no significant between-group differences regarding the bacterial species identified.</p><p><strong>Conclusion: </strong>The presence of urease-producing bacteria was associated with the development of IAD in community-dwelling women with urinary incontinence. Alkalization of the genital skin surface because of the contact between urine and urease-producing bacteria may compromise skin homeostasis. The bacterial species specifically involved in the development of IAD could not be determined.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5737-5747"},"PeriodicalIF":2.7,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11625642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical Activity Self-Efficacy Among Pregnant Women at High Risk for Gestational Diabetes Mellitus in China: A Cross-Sectional Study.","authors":"Xiao Yang, Yingli Song, Ji Zhang, Yan Wang, Hui Huang, Jing Zhang, Lingling Gao","doi":"10.2147/JMDH.S489118","DOIUrl":"10.2147/JMDH.S489118","url":null,"abstract":"<p><strong>Background: </strong>Physical activity could decrease the odds of pregnant women at high risk for gestational diabetes mellitus (GDM) developing GDM. Physical activity self-efficacy was the key predictor of physical activity. This study aimed to examine physical activity self-efficacy and identify its predictors among pregnant women at high risk for GDM in mainland China.</p><p><strong>Methods: </strong>A cross-sectional study was conducted in Zhengzhou, China, from October 2021 to February 2022. Two hundred fifty-two pregnant women at high risk for GDM completed the Pregnancy Physical Activity Self-efficacy Scale, the Social Support for Physical Activity Scale, the Knowledge of Physical Activity Questionnaire, the 7-item Generalized Anxiety Disorder Scale, the Edinburgh Postnatal Depression Scale, and a socio-demographic data sheet. Multiple linear regression was used.</p><p><strong>Results: </strong>Chinese pregnant women at high risk for GDM reported a moderate level of physical activity self-efficacy. The best-fit regression analysis revealed four predictors. Social support for physical activity was the strongest predictor, followed by knowledge of physical activity, intention to do physical activity, and anxiety symptoms.</p><p><strong>Conclusion: </strong>The study found that Chinese pregnant women at high risk for GDM had a moderate level of physical activity self-efficacy, which had 4 predictors. Healthcare professionals should make efforts to enhance pregnant women's social support, knowledge, and intention to do physical activity and decrease their anxiety symptoms to improve their physical activity self-efficacy.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5725-5736"},"PeriodicalIF":2.7,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11625193/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceived Barriers and Facilitators of Behavioral-Health Modality Change Adoption During the COVID-19 Pandemic: A Systematic Review.","authors":"Nicholas Sims-Rhodes, Hannah E Cornwell, Emily Barena, Vandy Dubre, Kimberly S Elliott, Eman H Nabulsi, Nelly Yuen, Sarah M Sass, Anastasia Miller, Yordanos M Tiruneh, Karan P Singh","doi":"10.2147/JMDH.S472060","DOIUrl":"10.2147/JMDH.S472060","url":null,"abstract":"<p><strong>Introduction: </strong>During the Coronavirus Disease 2019 pandemic, there was a surge in demand for mental health services worldwide, presenting challenges for healthcare institutions as they navigated changes in policy and safety regulations. In the United States, this resulted in many behavioral health modality changes to remain in compliance with the Center for Disease Control guidelines. A growing body of literature has documented these, yet few explored barriers and facilitators affecting the adoption of these modality delivery changes. The researchers conducted a systematic review using the PRISMA method, focusing on service delivery changes across healthcare systems in the United States from March 2020 to May 2022.</p><p><strong>Objective: </strong>The study objective was to identify barriers and facilitators affecting the adoption of changes to modality delivery of behavioral health services due to pandemic restrictions.</p><p><strong>Methods: </strong>This was a systematic review that utilized the PRISMA method. The researchers identified 445 initial articles from eight databases using predetermined keywords and implemented a three-round screening process to select the most pertinent articles for this review. The researchers used a thematic analysis focused on user-related, program-related, technology, and environment-related constructs relevant to engagement with digital mental health interventions, and also addressed provider and administrative-related barriers and facilitators of virtual behavioral health modality changes. Barriers and facilitators were operationalized using the Borghouts Model.</p><p><strong>Results: </strong>This systematic review revealed several common barriers and facilitators, including underdeveloped technology infrastructure, privacy and confidentiality concerns, poor technology literacy, availability of diverse technology options, provider technology training, and ease of integration into everyday life.</p><p><strong>Conclusion: </strong>This review provides insights into barriers and facilitators of modality change adoption, which could inform the development and implementation of virtual mental healthcare services and may help optimize the application of these services by improving our understanding and ability to overcome barriers influencing their adoption.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5695-5713"},"PeriodicalIF":2.7,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11624676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiologists vs Endocrinologists in Glycemic Control for Coronary Artery Disease Patients with Type 2 Diabetes: A Cross-Sectional Study.","authors":"Qin Xia, Qianwen Peng, Hefeng Chen, Weixia Zhang","doi":"10.2147/JMDH.S494004","DOIUrl":"10.2147/JMDH.S494004","url":null,"abstract":"<p><strong>Background: </strong>The comorbidity of coronary artery disease (CAD) and type 2 diabetes mellitus (T2DM) presents significant challenges in clinical management, particularly regarding glycemic control. The clinical management of CAD complicated by T2DM requires coordinated glycemic control, as poor management can exacerbate cardiovascular risks and increase morbidity and mortality. While endocrinologists traditionally manage diabetes, cardiologists are increasingly involved due to the cardiovascular risks associated with poor glycemic control. This study explores the current practices of glycemic management by cardiologists and endocrinologists in patients with CAD and T2DM, focusing on treatment intensification in a Chinese hospital setting.</p><p><strong>Methods: </strong>This cross-sectional study included 1,074 hospitalized patients with both CAD and T2DM, admitted to the Cardiology Department of Ruijin Hospital between January 2021 and December 2023. Data were retrospectively collected from electronic medical records, including demographic information, clinical characteristics, and treatment interventions. Patients were stratified by year, and differences in treatment strategies between cardiologists and endocrinologists were analyzed. Glycemic control was assessed using HbA1c levels, with treatment intensification defined by any adjustment in antidiabetic therapy and consideration for comprehensive cardiovascular risk factors.</p><p><strong>Results: </strong>Endocrinologists were significantly more likely to initiate treatment intensification, especially in cases of severe hyperglycemia (HbA1c ≥9.0%), while cardiologists' role in glycemic management was limited, with a preference for outpatient endocrinology referrals over in-hospital adjustments. Despite improvements in glycemic control, the percentage of patients achieving comprehensive cardiovascular risk management targets remained low.</p><p><strong>Conclusion: </strong>This study underscored the distinct yet complementary roles of cardiologists and endocrinologists in managing glycemic control among patients with CAD and T2DM, noting endocrinologists' more active involvement in treatment intensification. Future integrated care models should harness the unique expertise of both specialties to optimize patient outcomes, better address glycemic control needs, and enhance overall cardiovascular risk management in this high-risk patient population.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5715-5723"},"PeriodicalIF":2.7,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11624691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cell Nuclear Segmentation of B-ALL Images Based on MSFF-SegNeXt.","authors":"Xinzheng Wang, Cuisi Ou, Zhigang Hu, Aoru Ge, Yipei Wang, Kaiwen Cao","doi":"10.2147/JMDH.S492655","DOIUrl":"10.2147/JMDH.S492655","url":null,"abstract":"<p><strong>Purpose: </strong>The diagnosis and treatment of B-Lineage Acute Lymphoblastic Leukemia (B-ALL) typically rely on cytomorphologic analysis of bone marrow smears. However, traditional morphological analysis methods require manual operation, leading to challenges such as high subjectivity and low efficiency. Accurate segmentation of individual cell nuclei is crucial for obtaining detailed morphological characterization data, thereby improving the objectivity and consistency of diagnoses.</p><p><strong>Patients and methods: </strong>To enhance the accuracy of nucleus segmentation of lymphoblastoid cells in B-ALL bone marrow smear images, the Multi-scale Feature Fusion-SegNeXt (MSFF-SegNeXt) model is hereby proposed, building upon the SegNeXt framework. This model introduces a novel multi-scale feature fusion technique that effectively integrates edge feature maps with feature representations across different scales. Integrating the Edge-Guided Attention (EGA) module in the decoder further enhances the segmentation process by focusing on intricate edge details. Additionally, Hamburger structures are strategically incorporated at various stages of the network to enhance feature expression.</p><p><strong>Results: </strong>These combined innovations enable MSFF-SegNeXt to achieve superior segmentation performance on the SN-AM dataset, as evidenced by an accuracy of 0.9659 and a Dice coefficient of 0.9422.</p><p><strong>Conclusion: </strong>The results show that MSFF-SegNeXt outperforms existing models in managing the complexities of cell nucleus segmentation, particularly in capturing detailed edge structures. This advancement offers a robust and reliable solution for subsequent morphological analysis of B-ALL single cells.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5675-5693"},"PeriodicalIF":2.7,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11624523/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Study Progress and Analysis of Preventive Measures of Nursing Care for Chemotherapy-Induced Oral Mucositis in Pediatric Patients with Hematologic Malignancies: A Retrospective Study.","authors":"Ying Gu, Ning Chen, Min He, Duo Zheng, Juan Liu, Xia-Ling Fang","doi":"10.2147/JMDH.S489003","DOIUrl":"10.2147/JMDH.S489003","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the preventive and therapeutic effects of comprehensive nursing interventions on chemotherapy-induced oral mucositis in pediatric patients with hematologic malignancies.</p><p><strong>Methods: </strong>A retrospective analysis was conducted, and 80 pediatric patients with hematologic malignancies who underwent chemotherapy in our hospital from January 2020 to December 2023 were selected as the research subjects. According to different nursing intervention methods, the patients were divided into an experimental group (45 cases) and a control group (35 cases). The experimental group received comprehensive nursing interventions, including oral care, dietary guidance, and psychological support; the control group received routine care. The observation indicators included the incidence of oral mucositis, Oral Mucositis Daily Questionnaire (OMDQ) scores, pain index (Visual Analog Scale), and levels of inflammatory markers (IL-6 and CRP) in saliva.</p><p><strong>Results: </strong>In the first, second, and fourth weeks of chemotherapy, the incidence of oral mucositis in the experimental group was significantly lower than in the control group (P < 0.05), with a total incidence of 51.11% compared to 77.14% (P = 0.017). Before chemotherapy, no significant difference was observed in OMDQ or VAS scores between the groups (p>0.05). However, in the first, second, and fourth weeks, OMDQ and VAS scores in the experimental group were significantly lower than those in the control group (P < 0.001). Similarly, levels of IL-6 and CRP showed no baseline difference between groups but were significantly reduced in the experimental group during these weeks (P < 0.001).</p><p><strong>Conclusion: </strong>Comprehensive nursing interventions significantly reduce the incidence and severity of chemotherapy-induced oral mucositis in pediatric patients with hematologic malignancies, alleviate oral pain in pediatric patients, and effectively reduce the levels of inflammatory markers in saliva. The application of comprehensive nursing interventions in clinical nursing practice can improve the quality of care for pediatric patients with hematologic malignancies.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"17 ","pages":"5665-5673"},"PeriodicalIF":2.7,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11616427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142780304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}