Yixian Fu, Haiying Guan, Mingna Yu, Ping Jiang, Xiaojun He, Jidan Bao, Binjie Zhang, Yan Li
{"title":"The Current Situation and Future Trends of Ergothioneine in Biology and Medical Research: A Bibliometric Analysis.","authors":"Yixian Fu, Haiying Guan, Mingna Yu, Ping Jiang, Xiaojun He, Jidan Bao, Binjie Zhang, Yan Li","doi":"10.2147/JMDH.S547548","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Ergothioneine (EGT) is a natural antioxidant with multiple cellular protective properties. Recently, due to the improvement of production efficiency, EGT-related products have been more widely used. This paper studies the present situation of global research trends and hotspots of EGT to better grasp the direction of EGT research in biology and medical.</p><p><strong>Methods: </strong>We searched for relevant literature on EGT in the Web of Science Core Collection (WOSCC) and SciFinder databases on August 16, 2025. CiteSpace, VOSviewer, Tableau Desktop, Microsoft Excel, Bibliometrix program package and Biorender software are used for statistical analysis and visualisation.</p><p><strong>Results: </strong>A total of 800 articles were collected. It is found that the average growth rate of EGT's publications in biology and medicine from 1996 to 2025 was 17.33%. Based on the statistical results by country/region, it is evident that the primary focal areas of research activity within this domain exhibit concentrated distribution across the Americas, Asia, and Europe. Among the top ten authors in terms of publication volume, six are from Asia, three are from Poland in Europe, and one is from the United States (USA) in the Americas. The highest H-index ranking author is Halliwell B (169).</p><p><strong>Conclusion: </strong>Based on the keyword visualisation results, the current research hotspots are mainly divided into three clusters: 1) The absorption, distribution, anti-inflammatory and antioxidant biological molecular mechanisms of EGT in vivo. 2) The impact of EGT's antioxidant and anti-inflammatory effects on various diseases; 3) The source of EGT, the antioxidant potential of edible fungi in vitro, and its influencing factors. At present, research on EGT in biology and medicine mainly focuses on basic theories, so we believe that clinical trial research will become a hot trend in the future.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"6127-6149"},"PeriodicalIF":2.4000,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12484114/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Multidisciplinary Healthcare","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2147/JMDH.S547548","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Ergothioneine (EGT) is a natural antioxidant with multiple cellular protective properties. Recently, due to the improvement of production efficiency, EGT-related products have been more widely used. This paper studies the present situation of global research trends and hotspots of EGT to better grasp the direction of EGT research in biology and medical.
Methods: We searched for relevant literature on EGT in the Web of Science Core Collection (WOSCC) and SciFinder databases on August 16, 2025. CiteSpace, VOSviewer, Tableau Desktop, Microsoft Excel, Bibliometrix program package and Biorender software are used for statistical analysis and visualisation.
Results: A total of 800 articles were collected. It is found that the average growth rate of EGT's publications in biology and medicine from 1996 to 2025 was 17.33%. Based on the statistical results by country/region, it is evident that the primary focal areas of research activity within this domain exhibit concentrated distribution across the Americas, Asia, and Europe. Among the top ten authors in terms of publication volume, six are from Asia, three are from Poland in Europe, and one is from the United States (USA) in the Americas. The highest H-index ranking author is Halliwell B (169).
Conclusion: Based on the keyword visualisation results, the current research hotspots are mainly divided into three clusters: 1) The absorption, distribution, anti-inflammatory and antioxidant biological molecular mechanisms of EGT in vivo. 2) The impact of EGT's antioxidant and anti-inflammatory effects on various diseases; 3) The source of EGT, the antioxidant potential of edible fungi in vitro, and its influencing factors. At present, research on EGT in biology and medicine mainly focuses on basic theories, so we believe that clinical trial research will become a hot trend in the future.
期刊介绍：
The Journal of Multidisciplinary Healthcare (JMDH) aims to represent and publish research in healthcare areas delivered by practitioners of different disciplines. This includes studies and reviews conducted by multidisciplinary teams as well as research which evaluates or reports the results or conduct of such teams or healthcare processes in general. The journal covers a very wide range of areas and we welcome submissions from practitioners at all levels and from all over the world. Good healthcare is not bounded by person, place or time and the journal aims to reflect this. The JMDH is published as an open-access journal to allow this wide range of practical, patient relevant research to be immediately available to practitioners who can access and use it immediately upon publication.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
