Journal of Multidisciplinary Healthcare最新文献

{"title":"Insulin-Like Growth Factor Binding Protein, Acid-Labile Subunit Serum Level During the Acute and Convalescent Stage of SARS-CoV-2 Infection Depicted in a Longitudinal Study of 72 Patients During the First Wave of Pandemic.","authors":"Hossam Gad, Mohamed A Mahmoud, Mohamed Antar, Ahmed Sayed Ahmed, Krzysztof Laudanski","doi":"10.2147/JMDH.S515244","DOIUrl":"10.2147/JMDH.S515244","url":null,"abstract":"<p><strong>Purpose: </strong>Recent discoveries have pointed to the role of IGFALS immunological response to viral challenges, potentially leading to the emergence of a cytokine storm. Here, we investigate if serum IGFALS during the acute response to SARS-CoV-2 will not be likely to accompany immune response during acute phase and convalescence.</p><p><strong>Patients and methods: </strong>We recruited patients hospitalized with PCR-confirmed SARS-CoV-2 infection in 2020 and have blood collected after securing consent (t_adm), at 48 hours (t_48hrs), 7 days (t_7d), and after discharge from hospital (t_long). IGFALS and IGF-1 in serum were measured to assess dynamics of the illness and compared against non-specific inflammatory (C-reactive protein, IL-6) markers. Serum titers of IgG against proteins S and N assessed specific viral responses. Serum HMGB-1 was measured to assess level of necrosis. Demographic and clinical data were collected using electronic health records (EHR). Survival was determined at six months from admission.</p><p><strong>Results: </strong>No difference between serum IGFALS and IGF-1 levels was seen across the studied time points. IGFALS_adm showed significant positive correlations with IGFALS_48hrs (<i>r²</i> =0.18; <i>p</i><0.001), IGFALS_7d (<i>r²=</i>0.19; <i>p</i>=0.004), and IGFALS_long (<i>r² =</i> 0.23; <i>p</i>=0.045). IGFALS correlated negatively with IGF-1 but positively with growth hormone. IGFALS_adm showed significant inverse correlations with serum levels of HMGB1_adm (<i>r²=</i>0.26; <i>p =</i> <0.001) and t_48hr (<i>r² =</i> 0.27; <i>p</i><0.001). A significant correlation in the case of IGFALS_48hrs and CRP_48hrs (<i>r² =</i> 0.09, <i>p</i> = 0.021), IGFALS_long and CRP_long (<i>r² =</i> 0.271, <i>p</i>=0.039) was seen. Similar correlations were seen at 48 hours of sampling time for IL-6 (<i>r² =</i> 0.14, <i>p</i>=0.006). In terms of specific antiviral response, we observed that serum IGFALS_adm demonstrated correlation levels of serum IgG_adm (<i>r² =</i> 0.09, <i>p</i>=0.024). A positive correlation was found between length of stay in hospital or ICU and serum IGFALS_48hrs.</p><p><strong>Conclusion: </strong>Though IGFALS serum levels did not change significantly during SARS-CoV-2 infection, we observed correlations with markers of tissue destruction, C-reactive protein, IL-6, and length of hospital stay.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3447-3453"},"PeriodicalIF":2.7,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12176063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144326042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Themes Have to Be Considered in the Change Process Within Healthcare Organizations: Critical Analysis Review.","authors":"Hatem H Alsaqqa","doi":"10.2147/JMDH.S514080","DOIUrl":"10.2147/JMDH.S514080","url":null,"abstract":"<p><p>This review is intended to scrutinize different articles' types and determine a suitable process, model or framework for successful change in healthcare organizations. An integrative review of the literature was conducted. The search strategy began with three electronic databases (EBSCOhost, Google Scholar and PubMed). Considering the inclusion criteria, published articles that examined the change process within the healthcare organizations in the timeframe between 2000 and 2023 were chosen. Results extraction and analysis were completed on all the included articles. The final sample for this review comprised 19 studies. Based on common meanings and vital issues, 8 main themes contributing to change in healthcare organizations were integrated and grouped into four main categories (process dimensions), two adjunct factors (strategic dimensions) and one mediating tool and a result category. The four main categories are readiness to change, team-building, tangible and intangible variables' characteristics and the two adjunct factors are the metaphor design and time perspective. In addition to technology as a mediating role for change and the scale of the change as a resulted outcome. In general, collections that emerged in this study could be useful for framing initiatives to arouse organizational change in healthcare. However, little is known about the relative significance of each acknowledged factor within the change process in healthcare organizations. Various methodological research is recommended for narrowing this gap. Before beginning the change process, ongoing studies should focus on the psychological features of organizational scales for healthcare contexts.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3433-3446"},"PeriodicalIF":2.7,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12176066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144326053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemiarthroplasties via Posterior Trochanter Osteotomy for Treating Femoral Neck Fractures in Post-Cerebrovascular Disease.","authors":"Ying-Ao Jia, Li-Na Qiao, Zhi-Bin Liu, Liang Xue, Wei-Ming Bi, Meng-Fei Chen, Kai Kang, Fei Wang","doi":"10.2147/JMDH.S515576","DOIUrl":"10.2147/JMDH.S515576","url":null,"abstract":"<p><strong>Objective: </strong>The study investigated to examine the clinical outcomes of hemiarthroplasties using posterior femoral trochanter osteotomy for the treatment of femoral neck fractures in patients at the sequelae stage of cerebrovascular disease.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on the data of 53 patients who had been admitted to the Department of Orthopedics at Yan'an University Affiliated Hospital between May 2020 and May 2023. These patients had been diagnosed with femoral neck fractures and concurrent muscle weakness at the sequelae stage of cerebrovascular disease. The patients were divided into two groups: the osteotomy group (20 cases), which underwent hemiarthroplasties via an L osteotomy of the posterior femoral trochanter, and the conventional group (33 cases), which received hemiarthroplasties through the posterolateral approach of the greater trochanter. The two groups were compared on various parameters, including incision length, operation duration, intraoperative blood loss, postoperative drainage, blood transfusion rates, length of hospitalization, early mobilization post-surgery, hip joint function scores at follow-up visits (3 and 12 months), and the rate of postoperative dislocation of the femoral head.</p><p><strong>Results: </strong>No significant differences were observed between the two groups regarding incision length (<i>P</i>=0.06), operation duration (<i>P</i>=0.284), intraoperative blood loss (<i>P</i>=0.925), Blood transfusion rate (P=0.489), postoperative drainage (<i>P</i>=0.831) and length of hospital stay (<i>P</i>=0.341). However, the early mobilization time following surgery was shorter in the osteotomy group compared to the conventional group (<i>P</i><0.001). Additionally, the Harris hip joint function scores for the osteotomy group were significantly higher than those for the conventional group at both the 3- and 12-month postoperative assessments (<i>P=</i>0.003, <i>P=</i>0.004, respectively). The dislocation rate of the femoral head in the osteotomy group was lower than that in the conventional group with no statistical significance difference (<i>P</i>=0.521).</p><p><strong>Conclusion: </strong>The use of hemiarthroplasties via posterior femoral trochanter osteotomy demonstrates favorable clinical outcomes in the treatment of femoral neck fractures.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3391-3401"},"PeriodicalIF":2.7,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Qualitative and Quantitative Assessment of T2-Weighted Imaging Signal Variations in Prostate MRI Following Different Abstinence Periods: A Study in Young Healthy Men.","authors":"Wenjun Ma, Baoming Ren, Yanjun Gao, Weixian Bai","doi":"10.2147/JMDH.S517266","DOIUrl":"10.2147/JMDH.S517266","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluates the impact of an abstinence period on the image quality of high-field prostate magnetic resonance imaging (MRI).</p><p><strong>Methods: </strong>Male patients who underwent prostate MRI at Xi'an No.3 hospital between November 2021 and November 2022 were included in this study. The patients were divided into two groups based on whether they had ejaculated within three days prior to the MRI examination. Two radiologists assessed the boundary sharpness of the peripheral zone (PZ) and central gland (CG) using a double-blind 3-Point Likert scale. Regions of interest (ROIs) were marked bilaterally on the PZ and CG in sagittal T2-weighted images (T2WI). The signal intensity (SI) of the ROIs was measured, and the signal intensity ratio (SIR) was subsequently calculated. The Wilcoxon rank-sum test and independent samples <i>t</i>-test were employed to compare differences between the two groups.</p><p><strong>Results: </strong>A total of 50 young male patients participated in the study, with 20 patients having an abstinence period of more than 3 days and 30 patients having an abstinence period of 3 days or less. Qualitative analysis revealed that the prostate structures were more easily identifiable in the abstinence group compared to the ejaculation group (<i>P</i> ≤ 0.05). Quantitative analysis showed that the SIR of the PZ and CG was lower in the ejaculation group than in the abstinence group (<i>P</i> ≤ 0.05 for both), with a particularly significant difference observed in the peripheral zone.</p><p><strong>Conclusion: </strong>To obtain more accurate results in prostate MRI examinations, it is recommended that patients abstain from sexual activity for at least 3 days prior to the examination.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3403-3409"},"PeriodicalIF":2.7,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170790/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of Perioperative Comprehensive Care in Coronary Heart Disease Patients Undergoing Coronary Stent Implantation: A Study on the Collaboration of Cardiology Operating Room Nursing.","authors":"Yinglu Fan, Xiumin Lin","doi":"10.2147/JMDH.S527597","DOIUrl":"10.2147/JMDH.S527597","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the application effect of perioperative comprehensive care in patients with coronary heart disease undergoing coronary stent implantation.</p><p><strong>Methods: </strong>This retrospective cohort study included 150 patients who underwent coronary stent implantation at our hospital between January 2023 and January 2024. Based on documented perioperative nursing protocols, patients were categorized into an observation group (n=83), which received comprehensive nursing care (including psychological support, structured preoperative preparation, intraoperative coordination, enhanced postoperative management, and complication prevention), and a control group (n=67), which received standard institutional perioperative care. To minimize selection bias, propensity score-based inverse probability weighting was applied using baseline covariates. Outcomes assessed included anxiety levels, postoperative complication rates, length of hospital stay and recovery time, patient satisfaction, and changes in lipid profiles.</p><p><strong>Results: </strong>After weighting, baseline characteristics were well balanced between groups (standardized mean differences < 0.1). The observation group exhibited significantly lower state and trait anxiety scores at 24 hours postoperatively (P < 0.001). Rates of hematoma/bleeding, radial artery spasm/occlusion, arrhythmia, and fever were significantly lower in the observation group (P < 0.05). Hospital stay and postoperative recovery time were significantly reduced in the observation group (P < 0.001), and patient satisfaction scores were markedly higher (P < 0.001). Additionally, the observation group showed greater improvements in lipid profiles, with significant reductions in total cholesterol and LDL-C levels and an increase in HDL-C (P < 0.05).</p><p><strong>Conclusion: </strong>Comprehensive perioperative nursing care significantly improves clinical outcomes in patients undergoing coronary stent implantation, by alleviating psychological stress, reducing postoperative complications, shortening hospitalization and recovery time, and enhancing patient satisfaction. These findings support the integration of structured nursing interventions into standard perioperative protocols to optimize patient recovery and long-term cardiovascular management.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3423-3431"},"PeriodicalIF":2.7,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170817/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding and Overcoming Negative Attitudes That Hinder Adoption of Reablement in Dementia Care: An Explorative Qualitative Study.","authors":"Hanne Tuntland, Kiran Ashfaq, Magnus Zingmark, Silke F Metzelthin","doi":"10.2147/JMDH.S522515","DOIUrl":"10.2147/JMDH.S522515","url":null,"abstract":"<p><strong>Purpose: </strong>Dementia refers to a group of neuro-cognitive disorders that affect people worldwide. Reablement may facilitate people to maintain or regain abilities, encourage engagement in activities important to them, promote continued societal participation, and foster a meaningful life experience. However, the adoption of reablement in dementia care has been slow. This study aimed to explore the negative attitudes that hinder the adoption of reablement and to identify strategies to mitigate these factors.</p><p><strong>Methods: </strong>An exploratory qualitative approach involving semi-structured interviews was adopted. Interviews were conducted with reablement and/or dementia experts in five countries, namely Australia, Denmark, the Netherlands, Sweden, and the United Kingdom. The interviews were recorded and transcribed verbatim. The interviews were analyzed using a thematic analysis approach.</p><p><strong>Results: </strong>This study explored the views of 10 experts and identified negative attitudes that impede the adoption of reablement. These attitudes were grouped into five themes: 1) lack of understanding of the preserved capabilities in people with dementia, 2) reluctance and fear among family caregivers about disrupting established routines, 3) institutional barriers, 4) misinterpretation of what reablement is, and 5) complexity of the healthcare system. The proposed strategies to address these negative attitudes include enhancing dementia awareness, educating family caregivers, understanding caregiver burden, taking care of community education and destigmatization, improving clinical leadership, raising awareness about reablement evidence and practice, integrating reablement in educational curriculum, developing comprehensive policies, and improving access to services.</p><p><strong>Conclusion: </strong>This study highlights the importance of addressing and mitigating negative attitudes which obstruct adoption of reablement. By identifying these attitudes and exploring their origin, strategies can be formulated to overcome them. Successful adoption of these strategies is anticipated to enhance the quality of life of people with dementia and their caregivers.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3411-3422"},"PeriodicalIF":2.7,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12174993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144326054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global Research Trends in Oxidative Stress and Myocardial Fibrosis: A Dual-Software Bibliometric Study.","authors":"Sihan Jia, Yanjie Lian, Xiaolei Lai, Sinai Li, Juju Shang, Hongxu Liu","doi":"10.2147/JMDH.S525389","DOIUrl":"10.2147/JMDH.S525389","url":null,"abstract":"<p><strong>Objective: </strong>To conduct a visualization analysis of the literature on the role of oxidative stress in myocardial fibrosis (MF), explore the research progress, frontier hotspots, and development trends in this field, with the aim of providing a reference for the research on the prevention and treatment of MF related to oxidative stress.</p><p><strong>Methods: </strong>Web of Science was selected as the data source, and the relevant English literature on the role of oxidative stress in MF from the database establishment to December 31, 2024 was collected. Bibliometric methods were used for statistical analysis of the literature that met the research standards, and CiteSpace 6.3.R2 and VOSviewer 1.6.20 software were used for visualization of information such as publishing countries, institutions, authors, and keywords.</p><p><strong>Results: </strong>A total of 1831 SCI articles were included. The global publication volume showed an upward trend year by year, Publications increased by 16% annually after 2014, with China and the United States leading in publication volume. Keyword and cited literature analysis showed that the research hotspots and frontiers in this field mainly include the phenomenon of extracellular matrix (ECM) cell migration, the activation of the renin-angiotensin-aldosterone system, the regulatory mechanisms of oxidative stress in MF of different etiologies, and the mechanisms of action of oxidative stress in MF.</p><p><strong>Conclusion: </strong>The field of research into the role of oxidative stress in myocardial fibrosis is currently experiencing a period of rapid expansion. By leveraging the complementary strengths of CiteSpace for analyzing temporal and geographic trends, and VOSviewer for mapping collaboration networks, researchers have gained multidimensional insights into this area. The identification of the NLRP3 inflammasome as the fastest-growing research frontier, highlights its potential as a novel therapeutic target for clinical investigation. The mechanism by which oxidative stress activates the NLRP3 inflammasome signaling pathway to promote myocardial fibrosis is likely to emerge as a significant future research trend and warrants further in-depth exploration and study.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3357-3372"},"PeriodicalIF":2.7,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12168942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Bibliometric Analysis of Research Trends in Spousal Support for Breast Cancer Patients.","authors":"Yanping Liu, Yanxue Zhai, Limei Gao, Gantang Zhang","doi":"10.2147/JMDH.S476838","DOIUrl":"10.2147/JMDH.S476838","url":null,"abstract":"<p><strong>Background: </strong>The annual rise in breast cancer incidence is a significant issue that threatens women's health and imposes various physical and psychological effects on male spouses, while these spouses often serve as the primary source of social support for patients.</p><p><strong>Purpose: </strong>To conduct a systematic analysis of publications, countries, institutions, journals, disciplines, authors, keywords, and references related to spousal support for breast cancer patients using bibliometric methods.</p><p><strong>Methods: </strong>We searched the Web of Science Core Collection (WOSCC) for publications related to spousal support for breast cancer patients from January 2004 to December 2024. CiteSpace (6.4 R1, 64-bit Advanced Edition) and Microsoft Office Excel 2019 were used for bibliometric analysis and chart generation.</p><p><strong>Results: </strong>Our study analyzed 672 articles in the WOSCC database on spousal support for breast cancer patients over the past two decades. These publications have exhibited a trend of fluctuating growth. Research area primarily focuses on oncology, psychology, and nursing, with findings mainly published in <i>Psycho-Oncology</i> and <i>Supportive Care in Cancer</i>. The United States, Canada, and Australia lead this research domain, with the University of California system, Duke University, and Harvard University being the principal research institutions. Laura S. Porter and Donald H. Baucom are among the most prolific authors. The main keyword clusters include #1 caregiving burden, #2 quality of life, #3 sexual health, #4 qualitative study, #5 dyadic coping, and #6 marital status. The references focus on social psychology, intimate relationships, emotional communication, and coping interventions.</p><p><strong>Conclusion: </strong>This bibliometric study analyzes research on spousal support for breast cancer patients during the last two decades, outlining the publications, countries, institutions, journals, disciplines, and authors that have significantly influenced the field. Emerging trends in research on spousal support for breast cancer patients emphasize valuing the caregiving burden endured by spouses, exploring their support experiences, identifying spousal support barriers, and addressing intimacy challenges.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3373-3390"},"PeriodicalIF":2.7,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12168936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Latent Profile Analysis of Post-Surgical Psychological Distress in Young Thyroid Cancer Patients and Its Association with Self-Management Efficacy.","authors":"Jia Zhang, Dan Xiong, Chaixiu Li, Dan Li, Yinhuan Wang, Yanmei Fang, Ying Yang","doi":"10.2147/JMDH.S518462","DOIUrl":"10.2147/JMDH.S518462","url":null,"abstract":"<p><strong>Purpose: </strong>Psychological distress (PD) is one of the most prevalent psychological challenges among young patients with thyroid cancer. Recognizing the symptoms of psychological distress among young cancers at different stages is essential for improving their quality of life. This study aims to identify distinct profiles of psychological distress in young thyroid cancer patients post-surgery and assess differences in self-management efficacy across these profiles.</p><p><strong>Methods: </strong>This cross-sectional study was carried out in one general hospital in Chongqing, China. Participants completed the data collection on sociodemographic information, the specific Cancer Distress Scales for Adolescents and Young Adults (CDS-AYA), and the Strategies Used by People to Promote Health (SUPPH). Latent profile analysis was utilized to classify psychological distress into distinct subgroups, and analysis of covariance (ANCOVA) was employed to examine differences in self-management efficacy across these subgroups.</p><p><strong>Results: </strong>A total of 213 valid questionnaires were collected. Ultimately, three distinct profiles of psychological distress were identified: \"low PD group\" (67.1%), \"moderate PD group\" (25.8%), and \"high PD group\" (7.1%). Statistically significant differences were observed among these groups with respect to monthly economic income, underlying diseases, treatment modalities, tumor node metastasis (TNM) staging, and cervical lymph node dissection (F = 36.308, <i>P</i> < 0.001). Additionally, there were statistically significant variations in self-management efficacy scores across the three subgroups.</p><p><strong>Conclusion: </strong>Healthcare professionals ought to implement targeted interventions to tackle the heterogeneity of psychological distress, thereby assisting young with thyroid cancer in lowering their level of psychological distress and enhancing their ability to self-manage their disease.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3345-3356"},"PeriodicalIF":2.7,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12169003/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationships of Air Pollution and Meteorological Factors with Acute Aortic Dissection in Urumqi, China: A Distributed Lag Nonlinear Model Analysis.","authors":"Feng-Xia Wang, Qian-Ru Yuan, Jun Cui, Xiao-Qin Ke, Fei-Fei Wang, Xiang-Yu Dong, Ting Wang, Adiya Hahaerman, Yong-Fu Tong, Zhong-Xing Xu, Yan Feng, Yu-Kui Du","doi":"10.2147/JMDH.S509228","DOIUrl":"10.2147/JMDH.S509228","url":null,"abstract":"<p><strong>Objective: </strong>While prior studies link individual meteorological and air quality factors to acute aortic dissection (AAD), their combined lagged effects remain poorly understood. This study evaluates how air pollution and weather conditions collectively influence AAD risk in Urumqi, China.</p><p><strong>Methods: </strong>The results show that the onset of AAD predominantly occurs in the cold season, exhibiting distinct seasonal characteristics. Meanwhile, PM2.5, PM10, SO2, and the average dew point are significantly correlated with an increased risk of AAD. Males are more sensitive to certain pollutants (PM2.5, PM10, SO2) and the average dew point. In contrast, in females, CO surprisingly has a protective effect. Among people aged ≤ 50, O3_8h and the average dew point have a strong cumulative correlation with the incidence of AAD, while CO exposure and the maximum sustained wind speed are negatively correlated with the incidence of AAD. Individuals aged over 50 show little sensitivity to air pollutants and meteorological conditions. Under extreme conditions, the concentrations of PM2.5, SO2, and PM10 can still increase the risk of AAD onset.</p><p><strong>Conclusion: </strong>Air pollution and meteorological factors significantly impact AAD risk, highlighting the need to consider these factors in prevention and management strategies.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3331-3343"},"PeriodicalIF":2.7,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12166857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}