{"title":"Echoes of the larynx: harnessing acoustic analysis as a key tool for monitoring laryngeal health in inhalational therapy patients.","authors":"Sharad Ashish, Nirmal Coumare V, Pajanivel R, Padmanabhan Karthikeyan","doi":"10.1017/S0022215125102752","DOIUrl":"10.1017/S0022215125102752","url":null,"abstract":"<p><strong>Objectives: </strong>This study evaluated laryngeal changes and voice quality in patients with obstructive lung disease treated with combination inhalational agents.</p><p><strong>Methods: </strong>A prospective observational study at a tertiary care hospital in southern India included 112 newly diagnosed obstructive lung disease patients. Initial assessments involved history-taking, clinical examination, direct laryngoscopy and voice analysis using PRAAT® software. Parameters such as mean pitch, jitter, shimmer, harmonic-to-noise ratio and maximum phonation time were measured, with follow-ups at 3, 6 and 12 months.</p><p><strong>Results: </strong>Patients had a mean age of 43.05 years. Progressive laryngeal changes, including oedema (5.3 per cent) and hyperaemia (7.1 per cent), were noted by 12 months. Significant increases in shimmer and jitter, along with decreases in harmonic-to-noise ratio and maximum phonation time, indicated deteriorating voice quality (<i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>Long-term inhalational corticosteroid use in obstructive lung disease patients leads to progressive laryngeal changes and voice deterioration, emphasising the need for vocal function monitoring and preventive strategies.</p>","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"1-6"},"PeriodicalIF":0.8,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Li Lijuan, Luo Jiasheng, Yang Yintong, Zhu Guanxia, Huo Meixu, Zhai Songyu, Song Shanghua
{"title":"Prognostic analysis and nomogram prediction model construction of severe full-frequency sudden sensorineural hearing loss.","authors":"Li Lijuan, Luo Jiasheng, Yang Yintong, Zhu Guanxia, Huo Meixu, Zhai Songyu, Song Shanghua","doi":"10.1017/S0022215125102582","DOIUrl":"https://doi.org/10.1017/S0022215125102582","url":null,"abstract":"<p><strong>Objectives: </strong>This stidy aimed to identify factors influencing prognosis in severe full-frequency sudden sensorineural hearing loss and develop an early prognostic tool.</p><p><strong>Methods: </strong>A total of 194 patients with severe full-frequency sudden sensorineural hearing loss were analyzed. Univariate analysis screened variables, followed by multivariate logistic regression to construct a nomogram prediction model. Model performance was evaluated using a receiver operating characteristics curve.</p><p><strong>Results: </strong>Significant differences (<i>p</i> < 0.05) were found between ineffective and effective treatment groups in gender, age, contralateral ear hearing, duration of hearing loss, dizziness/vertigo, hypertension, platelet count and fibrinogen levels (Fib1, Fib2, Fib3). The nomogram model, incorporating these factors, showed good calibration. The receiver operating characteristics curve analysis revealed an area under the curve of 0.880 (95 per cent confidence interval: 0.829-0.931), with sensitivity of 80.7 per cent and specificity of 87.5 per cent.</p><p><strong>Conclusion: </strong>The nomogram model, integrating 11 factors, effectively predicts prognosis in severe full-frequency sudden sensorineural hearing loss.</p>","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"1-8"},"PeriodicalIF":1.1,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144584146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Head and Neck Cancer: United Kingdom National Multidisciplinary Guidelines, Sixth Edition - CORRIGENDUM.","authors":"Jarrod J Homer, Stuart C Winter","doi":"10.1017/S0022215125102491","DOIUrl":"https://doi.org/10.1017/S0022215125102491","url":null,"abstract":"","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"1"},"PeriodicalIF":1.1,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144497354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Scapular tip free flap reconstruction of complex midface defects using electromagnetic navigation.","authors":"Jérôme Costisella, Mathieu Belzile, Pierre-Hugues Fortier, Laurent Fradet","doi":"10.1017/S002221512510248X","DOIUrl":"10.1017/S002221512510248X","url":null,"abstract":"<p><strong>Problem: </strong>The virtues of the scapular tip free flap for reconstruction of complex midface oncologic defects have been claimed by many. To obtain optimal functional and aesthetic results, precise positioning of the free flap used for reconstruction is paramount.</p><p><strong>Methods: </strong>Four cases illustrate our approach to midface reconstruction with angular branch-based scapular tip flaps. A standard surgical navigation device was used both to plan bone cuts for the oncologic resection and to optimise the positioning of the flap.</p><p><strong>Results: </strong>Case 1 illustrates the usefulness of navigation for reconstruction of total palato-septectomy defects, using a horizontally positioned flap. Optimal neo-palate height, alignment of the anterior nasal spine and nasal projection were obtained. For cases 2-4, vertical inset of the flap yielded optimal midface projection and orbital floor position.</p><p><strong>Conclusion: </strong>Surgical navigation systems are useful adjuncts for midface reconstruction.</p>","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"1-5"},"PeriodicalIF":1.1,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144497355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Omidvari, Alimohamad Asghari, Mohsen Ahadi, Ahmad Daneshi, Zahra Azad
{"title":"Vestibular dysfunction and hearing outcome in idiopathic sudden sensorineural hearing loss.","authors":"Ali Omidvari, Alimohamad Asghari, Mohsen Ahadi, Ahmad Daneshi, Zahra Azad","doi":"10.1017/S0022215125000672","DOIUrl":"https://doi.org/10.1017/S0022215125000672","url":null,"abstract":"<p><strong>Objective: </strong>To describe vestibular dysfunction accompanied by sudden sensorineural hearing loss and explore its potential prognostic role.</p><p><strong>Methods: </strong>A total of 44 Idiopathic Sudden Sensorineural Hearing loss cases were enrolled. Pure tone audiometry (PTA) was performed at the first visit and three months after standard therapy. Patients' improvement and severity of hearing loss were categorised based on Siegel and American Speech and Hearing Association criteria. Their recovery rate and factors affecting recovery were explored.</p><p><strong>Results: </strong>The mean age of the participants was 52.1 years. The caloric and cervical vestibular-evoked myogenic potential test abnormalities were detected in 36.4 and 31.8 per cent of participants. Vertigo was present in 36.4 per cent at the first visit. Based on American Speech and Hearing Association criteria, 16 patients experienced at least 1 grade improvement to a less severe hearing loss status at the follow up. A total of 31.7 per cent of patients demonstrated complete or partial recovery. Vestibular dysfunction was associated with poorer PTA results.</p><p><strong>Conclusion: </strong>Abnormal caloric and cervical vestibular-evoked myogenic potential tests, as well as the presence of vertigo, can indicate more profound inner-ear damage.</p>","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"1-5"},"PeriodicalIF":1.1,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144484758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tomàs Pérez-Carbonell, Miguel Orts-Alborch, Vanesa Pérez-Guilén, Ignacio Pla-Gil, Clara Espina-González, Maria Aragonés-Redó, Jaime Marco-Algarra
{"title":"Beyond frequency: duration, intensity, and quality of life in Ménière's disease.","authors":"Tomàs Pérez-Carbonell, Miguel Orts-Alborch, Vanesa Pérez-Guilén, Ignacio Pla-Gil, Clara Espina-González, Maria Aragonés-Redó, Jaime Marco-Algarra","doi":"10.1017/S0022215125102624","DOIUrl":"10.1017/S0022215125102624","url":null,"abstract":"<p><strong>Objective: </strong>To analyse the evolution of the vertigo index and its relationship with perceived disability in unilateral and bilateral Ménière's disease, assessing differences based on disease progression and clinical subtypes.</p><p><strong>Methods: </strong>A longitudinal descriptive study was conducted on unilateral and bilateral Ménière's disease patients, with data collected between 1977 and 2023 from two referral centres. Clinical and functional data were retrospectively reviewed to ensure compliance with updated diagnostic criteria. The vertigo index, integrating episode duration and frequency, quantified vertigo burden. Functional impact was assessed using the six-item American Academy of Otolaryngology Head and Neck Surgery disability scale, categorising patients into mild or moderate/severe disability groups.</p><p><strong>Results: </strong>Bilateral Ménière's disease patients had a higher proportion of moderate/severe episodes (31.4 per cent) than unilateral Ménière's disease patients (11 per cent). In unilateral Ménière's disease patients, disability perception increased after 20 years of disease evolution. The vertigo index declined over time, except in later stages, where episodes were more disabling.</p><p><strong>Conclusion: </strong>These findings underscore the need for long-term follow up, particularly in bilateral Ménière's disease, where greater disability was observed. Disease management should adapt over time, addressing both vertigo burden and psycho-affective consequences.</p>","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"1-7"},"PeriodicalIF":1.1,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144475593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bilateral radiation-induced squamous cell carcinoma of the external auditory canal: the effect of immunosuppressive therapy.","authors":"Cole Needham, Jonn Wu, Desmond A Nunez","doi":"10.1017/S0022215125102569","DOIUrl":"10.1017/S0022215125102569","url":null,"abstract":"<p><strong>Background: </strong>Squamous cell carcinoma of the external auditory canal is rare, with bilateral cases even rarer. We report the management of a patient with bilateral external auditory canal squamous cell carcinoma related to radiotherapy and immunosuppression.</p><p><strong>Case report: </strong>A 47-year-old woman with a history of radiotherapy 14 years prior and renal transplantation 6 years prior presented with bilateral external auditory canal squamous cell carcinoma. Squamous cell carcinoma was excised with a purely surgical approach. The two operations included a tympanic membrane graft to preserve hearing on the left side. The patient remains disease-free six months post-op. She uses a bone-conduction hearing aid to good effect on the right side and has mild hearing loss on the left. The operative areas have healed well.</p><p><strong>Discussion: </strong>The patient's previous radiotherapy and immunosuppression may have contributed to her bilateral external auditory canal squamous cell carcinoma. Preventative positron emission tomography scans have the potential to identify second malignancies early, allowing more conservative treatment plans.</p>","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"1-3"},"PeriodicalIF":1.1,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144475594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The saccule and gravity.","authors":"Hiroaki Ichijo, Hisako Ichijo","doi":"10.1017/S0022215125102600","DOIUrl":"10.1017/S0022215125102600","url":null,"abstract":"<p><strong>Background: </strong>The important role of the saccule is the sensing of gravity. In other words, gravity always stimulates the macula of the saccule.</p><p><strong>Objectives: </strong>The aim of this study was to clarify whether nystagmus and dizziness occur by intentional changes upon stimulation to the saccules.</p><p><strong>Methods: </strong>The subjects were eight healthy humans. Experiment 1: Subjects were asked to maintain a supine position to check for nystagmus and dizziness. Experiment 2: Subjects were asked to tilt their heads 45º to the left in the supine position to check for nystagmus and dizziness. Experiment 3: Subjects were asked to maintain a left-ear-down 90º position to check for nystagmus and dizziness.</p><p><strong>Results: </strong>In all the experiments, no one revealed nystagmus and no one complained of dizziness.</p><p><strong>Conclusion: </strong>Neither nystagmus nor dizziness occurs by intentional changes in the stimulation to the saccules.</p>","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"1-5"},"PeriodicalIF":1.1,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144368986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emre Orhan, Serdar Can Güven, Recep Karamert, Zafer Günendi, Bülent Gündüz
{"title":"A new perspective on primary Sjogren's syndrome: investigation of vestibular and balance functions.","authors":"Emre Orhan, Serdar Can Güven, Recep Karamert, Zafer Günendi, Bülent Gündüz","doi":"10.1017/S0022215125000647","DOIUrl":"10.1017/S0022215125000647","url":null,"abstract":"<p><strong>Objectives: </strong>Sjogren's syndrome is a chronic inflammatory condition with an autoimmune history that primarily affects women in middle age (male to female ratio is 1:9). This study aims to evaluate the functional balance status of the patients in primary Sjogren's syndrome and to examine their peripheral and central vestibular functions.</p><p><strong>Methods: </strong>A total of 24 patients with primary Sjogren's syndrome and 26 sex-matched controls were included in this study. Gaze, saccade, tracking, optokinetic, video head impulse and sensory organisation tests were performed on the participants.</p><p><strong>Results: </strong>Significant decreases were observed in video head impulse and sensory organisation tests in participants with Sjogren's syndrome compared to controls.</p><p><strong>Conclusion: </strong>This study documented the findings of patients with Sjogren's syndrome from a vestibular and balance perspective. The study's findings have guided relevant professionals in the follow-up of patients with Sjogren's syndrome to improve patients' daily life, balancing performance and quality of life.</p>","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"1-6"},"PeriodicalIF":1.1,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144333283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sanem Can Çolak, Deniz Uğur Cengİz, Tuba Bayindir, Birgül Cumurcu
{"title":"An Evaluation of Vestibular Functions in Substance Misuse.","authors":"Sanem Can Çolak, Deniz Uğur Cengİz, Tuba Bayindir, Birgül Cumurcu","doi":"10.1017/S0022215125000209","DOIUrl":"https://doi.org/10.1017/S0022215125000209","url":null,"abstract":"","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"1-18"},"PeriodicalIF":1.1,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}