Journal of Laryngology and Otology最新文献

Influence of menstrual cycle phase and serum oestrogen levels on tympanoplasty outcomes in women. 月经周期和血清雌激素水平对女性鼓室成形术结果的影响。

IF 1.1 4区医学

Journal of Laryngology and Otology Pub Date : 2026-10-15 DOI: 10.1017/S0022215126105829

Nurcan Yoruk, Ayse Nur Aksoy, Hazal Altunok, Erdi Ozdemir, Ozgur Yoruk

{"title":"Influence of menstrual cycle phase and serum oestrogen levels on tympanoplasty outcomes in women.","authors":"Nurcan Yoruk, Ayse Nur Aksoy, Hazal Altunok, Erdi Ozdemir, Ozgur Yoruk","doi":"10.1017/S0022215126105829","DOIUrl":"https://doi.org/10.1017/S0022215126105829","url":null,"abstract":"Objective: To evaluate whether menstrual cycle phase and serum oestrogen influence tympanoplasty outcomes in premenopausal women.Methods: Eighty women with small central tympanic membrane perforations (follicular phase, days 1-5, n = 40; ovulatory phase, days 12-16, n = 40) underwent endoscopic transcanal type I tympanoplasty. Outcomes were anatomical success (at 12 weeks) and hearing improvement. Pre-operative serum oestrogen and its predictive value were assessed.Results: Graft success was higher in the ovulatory than follicular phase (90 vs 70 per cent, p = 0.025). Hearing gain was greater in the ovulatory phase (12.35 ± 4.84 dB vs 4.70 ± 3.92 dB, p < 0.001). Serum oestrogen was significantly higher in the ovulatory phase. Receiver operating characteristic analysis showed modest predictive performance (area under the curve = 0.643).Conclusion: Tympanoplasty during the ovulatory phase is associated with improved anatomical and functional outcomes, suggesting that endogenous oestrogen benefits tympanic membrane healing.","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"1-6"},"PeriodicalIF":1.1,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149182507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MOBETRON™ intra-operative radiotherapy for head and neck cancer: a UK first. MOBETRON™术中放疗治疗头颈癌：英国首创。

IF 1.1 4区医学

Journal of Laryngology and Otology Pub Date : 2026-09-01 DOI: 10.1017/S0022215126105350

Niamh Gibson, Shanmugasundaram Ramkumar, Tahwinder Singh, Nimesh N Patel

{"title":"MOBETRON™ intra-operative radiotherapy for head and neck cancer: a UK first.","authors":"Niamh Gibson, Shanmugasundaram Ramkumar, Tahwinder Singh, Nimesh N Patel","doi":"10.1017/S0022215126105350","DOIUrl":"10.1017/S0022215126105350","url":null,"abstract":"Background: Head and neck cancer is one of the common cancers worldwide. Despite comprehensive treatment programmes, the recurrence rate of these cancers is high with loco-regional recurrence rates of 40-50 per cent. Current salvage options have limited efficacy and significant morbidity. Intra-operative radiotherapy or intra-operative electron radiotherapy offers a potential for improved locoregional control when combined with surgical salvage with less morbidity.Case report: We report the implementation of intra-operative electron radiotherapy treatment and a case of management of a patient with locoregional recurrence after previous external beam radiotherapy treatment for squamous cell carcinoma of the tonsil.Conclusion: This is the first UK head and neck cancer case treated with MOBETRON™ intra-operative radiotherapy. The patient remained disease free for over three years with no adverse side-effects. Intra-operative electron radiotherapy as adjuvant treatment to surgical salvage for recurrent head and neck cancer HNC may improve locoregional control, survival and quality of life.","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"1007-1010"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148412047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prophylactic and therapeutic use of botulinum toxin in post-parotidectomy fistulas and sialocele: a scoping review. 肉毒毒素在腮腺切除术后瘘管和涎腺囊肿中的预防和治疗应用：范围综述。

IF 1.1 4区医学

Journal of Laryngology and Otology Pub Date : 2026-09-01 DOI: 10.1017/S0022215126105337

Cesar Alturo, Alvaro Sanabria

{"title":"Prophylactic and therapeutic use of botulinum toxin in post-parotidectomy fistulas and sialocele: a scoping review.","authors":"Cesar Alturo, Alvaro Sanabria","doi":"10.1017/S0022215126105337","DOIUrl":"10.1017/S0022215126105337","url":null,"abstract":"Introduction: Sialocele and parotid fistula are complications following parotidectomy. Botulinum toxin type A has emerged as a less invasive alternative to prevent or treat them. This scoping review aimed to map the available evidence regarding the preventive and therapeutic use of botulinum toxin type A.Methods: Studies involving patients with salivary gland fistulas or sialocele prevented or treated were included. A comprehensive search was conducted in PubMed, Scopus and Google Scholar.Results: Thirty-five studies, including 681 patients, were analysed. Most were case reports or case series. Among prophylactic studies, the sialocele rate in botulinum toxin type A groups was 3.4 per cent versus 16.4 per cent in controls, without statistical significance. Among patients treated, resolution was achieved in 92 per cent of cases. Methodological limitations included small sample sizes, heterogeneity in protocols and lack of standardised outcome measures.Conclusions: Botulinum toxin type A shows a physiological effect on salivary flow reduction; however, available evidence does not yet support definitive conclusions on efficacy.","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"946-953"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148412130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of nasal obstruction severity on carotid intima-media thickness in patients with nasal septal deviation. 鼻塞严重程度对鼻中隔偏曲患者颈动脉内膜-中膜厚度的影响。

IF 1.1 4区医学

Journal of Laryngology and Otology Pub Date : 2026-09-01 DOI: 10.1017/S0022215126105374

Bülent Ulusoy, Abdullah Tunçez, Osman Gül, Muslu Kazım Körez, Hüseyin Tezcan, Ömer Erdur

{"title":"Impact of nasal obstruction severity on carotid intima-media thickness in patients with nasal septal deviation.","authors":"Bülent Ulusoy, Abdullah Tunçez, Osman Gül, Muslu Kazım Körez, Hüseyin Tezcan, Ömer Erdur","doi":"10.1017/S0022215126105374","DOIUrl":"10.1017/S0022215126105374","url":null,"abstract":"Objectives: This study aimed to evaluate the association between the severity of nasal obstruction and carotid intima-media thickness in patients with nasal septal deviation.Methods: This prospective study included 60 patients scheduled for septoplasty and 50 age-, sex- and body mass index-matched healthy controls. Correlation analyses and receiver operating characteristics curve analyses were performed to determine associations and optimal cutoff values.Results: Both right (0.62 ± 0.12 mm) and left (0.63 ± 0.12 mm) common carotid artery intima-media thickness values were significantly higher in the nasal septal deviation group compared to controls (0.51 ± 0.09 mm and 0.51 ± 0.07 mm, respectively; p < 0.001). Receiver operating characteristics analyses revealed that Visual Analogue Scale greater than or equal to 7.5 (sensitivity 85.7 per cent; specificity 67.4 per cent) and Nasal Obstruction Symptom Evaluation greater than or equal to 72.5 (sensitivity 92.9per cen; specificity 65.1 per cent) reliably predicted elevated carotid intima-media thickness (>0.7 mm).Conclusion: Nasal septal deviation-related nasal obstruction was significantly associated with increased carotid intima-media thickness, suggesting a possible contribution to cardiovascular risk. Larger multicenter studies are warranted to validate these findings. The Australian New Zealand CTN: ACTRN12619000347167.","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"981-987"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148412113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Building CauterClay, a low-cost, high-fidelity training model for nasal cautery: a technical report. 构建CauterClay，一种低成本、高保真的鼻烧灼训练模型：技术报告。

IF 1.1 4区医学

Journal of Laryngology and Otology Pub Date : 2026-09-01 DOI: 10.1017/S0022215126105465

Wesley Kai-Xian McLoughlin, Pin-Yu Chen, Valerie Yujin Kim, Stephen Jones

{"title":"Building CauterClay, a low-cost, high-fidelity training model for nasal cautery: a technical report.","authors":"Wesley Kai-Xian McLoughlin, Pin-Yu Chen, Valerie Yujin Kim, Stephen Jones","doi":"10.1017/S0022215126105465","DOIUrl":"10.1017/S0022215126105465","url":null,"abstract":"Objectives: This study aimed to design and evaluate a low-cost, high-fidelity nasal cautery model (CauterClay) for increasing user confidence in carrying out nasal cautery.Methods: We created CauterClay with an air-dry clay scaffold, simulated nasal mucosal lining and bleeding point. We carried out single-centre assessment with a variety of nasal cautery-naive and experienced doctors. Doctors were asked to complete pre- and post-induction surveys regarding confidence, prior experience and model fidelity.Results: CauterClay use was associated with a statistically significant increase in user confidence in carrying out nasal cautery. All nasal cautery-naive users reported an increase in self-reported confidence following model use. Users rated the fidelity of our model highly, here we demonstrate how others can create their own CauterClay model.Conclusion: Here we outline the first published low-cost, high-fidelity nasal cautery model. Our findings demonstrate it is associated with increased user confidence, suggesting it may be valuable for training nasal cautery-naive clinicians.","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"998-1003"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148578955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Audiological Outcomes in 465 Primary Myringoplasties: Reporting Pitfalls and Lessons Learned - ERRATUM. 465例原发性耳膜成形术的听力学结果：报告缺陷和经验教训-勘误。

IF 1.1 4区医学

Journal of Laryngology and Otology Pub Date : 2026-09-01 DOI: 10.1017/S0022215126105933

Resul Arjin Öksüz, Simon E Thurnheer, Rong Yu, Gunther Pabst, Christoph Schlegel, Thomas Linder

引用次数: 0

Septal melanoma: does surgical excision confer a potential survival benefit? A single centre's experience and literature review. 鼻中隔黑色素瘤：手术切除是否具有潜在的生存益处？单一中心的经验和文献综述。

IF 1.1 4区医学

Journal of Laryngology and Otology Pub Date : 2026-09-01 DOI: 10.1017/S0022215126105283

Zakariya Sattar, Andrew James Mowat, James Barraclough

{"title":"Septal melanoma: does surgical excision confer a potential survival benefit? A single centre's experience and literature review.","authors":"Zakariya Sattar, Andrew James Mowat, James Barraclough","doi":"10.1017/S0022215126105283","DOIUrl":"10.1017/S0022215126105283","url":null,"abstract":"Objectives: Intranasal melanoma is a rare, aggressive malignancy with poor prognosis, with five-year survival rates of 6-30 per cent. We hypothesised that intranasal melanoma confined to the nasal septum may have a more favourable outcome if detected early and treated with wide local excision or septectomy. This case series reviews management at a regional head and neck centre.Methods: Intranasal melanoma cases were identified from a list of those with International Classification of Diseases - Revision 10 code C30.0 (\"neoplasm of nasal cavity\") and analysed retrospectively for survival time and treatment modality.Results: Eleven patients (May 2010-December 2024) were identified. Eight (72.7 per cent) underwent surgery. Patients treated with subtotal septectomy or rhinectomy had longer mean survival (250 weeks) compared to those receiving endoscopic debulking and chemoradiotherapy (104 weeks).Conclusion: Our findings may identify utility of early septectomy in patients with septal disease. Furthermore, larger studies are required to elucidate the role of septectomy in septal intranasal melanoma.","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"993-997"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148302008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence and recovery of taste dysfunction after stapedectomy in otosclerosis: a clinical study of 320 patients. 320例耳硬化症镫骨切除术后味觉功能障碍患病率及恢复情况的临床研究

IF 1.1 4区医学

Journal of Laryngology and Otology Pub Date : 2026-09-01 DOI: 10.1017/S0022215126105271

Nader Saki, Soheila Nikakhlagh, Maryam Kardooni, Seyedeh Marzieh Hosseini, Arash Bayat

{"title":"Prevalence and recovery of taste dysfunction after stapedectomy in otosclerosis: a clinical study of 320 patients.","authors":"Nader Saki, Soheila Nikakhlagh, Maryam Kardooni, Seyedeh Marzieh Hosseini, Arash Bayat","doi":"10.1017/S0022215126105271","DOIUrl":"10.1017/S0022215126105271","url":null,"abstract":"Objectives: To investigate the prevalence, characteristics and predictors of taste dysfunction following stapedectomy in patients with otosclerosis.Methods: This study was conducted on 320 patients who underwent primary stapedectomy. Demographic data, audiometric outcomes and taste function were assessed pre-operatively, one week, six weeks and one year post-operatively.Results: Taste disturbance occurred in 35.6 per cent of patients at 1 week, 7.8 per cent at 6 weeks, and 0.9 per cent at 1 year (p < 0.001). The most frequent symptoms were reduced taste sensation (66.6 per cent), metallic taste (60.5 per cent), and altered perception of salty (53.5 per cent) and sweet (41.2 per cent) flavours. Chorda tympani nerve stretching (odds ratio = 6.30, p < 0.001) and prosthesis diameter of 0.6 mm (odds ratio = 2.51, p < 0.001) were identified as the strongest independent predictors of taste disturbance.Conclusion: Taste disturbance is a relatively common but transient complication of stapedectomy. Chorda tympani nerve stretching, prosthesis diameter and older age are significant predictors.","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"973-976"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148368726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pro-inflammatory diet association with sudden sensorineural hearing loss: a case-control study. 促炎饮食与突发性感音神经性听力损失的关系：一项病例对照研究。

IF 1.1 4区医学

Journal of Laryngology and Otology Pub Date : 2026-09-01 DOI: 10.1017/S0022215126105416

Kadir Sinasi Bulut, Basak Yalciner, Burak Celik, Esra Zeynep Karakus, Erva Nur Topaloglu

{"title":"Pro-inflammatory diet association with sudden sensorineural hearing loss: a case-control study.","authors":"Kadir Sinasi Bulut, Basak Yalciner, Burak Celik, Esra Zeynep Karakus, Erva Nur Topaloglu","doi":"10.1017/S0022215126105416","DOIUrl":"10.1017/S0022215126105416","url":null,"abstract":"Objectives: This study investigated whether the inflammatory potential of diet, assessed by the Dietary Inflammatory Index, is associated with sudden sensorineural hearing loss by comparing patients with sudden sensorineural hearing loss and healthy controls.Methods: This retrospective case-control study included 30 patients with sudden sensorineural hearing loss and 32 matched controls. Dietary intake in the preceding 12 months was assessed by food frequency questionnaire, and Dietary Inflammatory Index scores were calculated. Between-group comparisons and receiver operating characteristics analysis were performed.Results: Mean Dietary Inflammatory Index score was significantly higher in the sudden sensorineural hearing loss group than in controls (2.27 ± 1.21 vs. 1.46 ± 1.14; p = 0.01). Patients with sudden sensorineural hearing loss had higher energy, saturated fat and cholesterol intake, while omega-3 fatty acid and fibre intake were lower (p < 0.05). Dietary Inflammatory Index scores demonstrated moderate discriminative ability for sudden sensorineural hearing loss (area under the curve = 0.690; p = 0.005).Conclusion: A pro-inflammatory dietary profile may be associated with increased sudden sensorineural hearing loss risk and may contribute to understanding modifiable risk factors.","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"988-992"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148430547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic value of gross tumour volume in laryngeal cancer: a systematic review and meta-analysis. 喉癌总肿瘤体积的预后价值：一项系统回顾和荟萃分析。

IF 1.1 4区医学

Journal of Laryngology and Otology Pub Date : 2026-09-01 DOI: 10.1017/S0022215126105313

Shahid Iqbal, Saad Illahi, Rumail Zaheer, Ashir Iqbal, Ely Cheikh Boussaty, Charles S Coffey

{"title":"Prognostic value of gross tumour volume in laryngeal cancer: a systematic review and meta-analysis.","authors":"Shahid Iqbal, Saad Illahi, Rumail Zaheer, Ashir Iqbal, Ely Cheikh Boussaty, Charles S Coffey","doi":"10.1017/S0022215126105313","DOIUrl":"10.1017/S0022215126105313","url":null,"abstract":"Objectives: Gross tumour volume has been proposed as a complementary prognostic marker in laryngeal squamous cell carcinoma. This systematic review and meta-analysis evaluates the prognostic value of pre-treatment gross tumour volume.Methods: MEDLINE, Embase and Scopus were systematically searched according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Studies reporting pre-treatment gross tumour volume and survival outcomes in laryngeal cancer were included. The primary outcome was overall survival, and the secondary outcome was disease-free survival. Hazard ratios were pooled using random-effects meta-analysis. Risk of bias was assessed using the Quality in Prognosis Studies tool, and certainty of evidence using the Grading of Recommendations Assessment, Development and Evaluation approach.Results: Eight retrospective studies including 1351 patients were included. Increasing gross tumour volume was significantly associated with worse overall survival (pooled hazard ratio per 1 cm3 increase: 1.03; 95 per cent confidence interval: 1.02-1.05), with a similar association observed for disease-free survival. Overall risk of bias was moderate.Conclusions: Higher gross tumour volume is independently associated with poorer survival in laryngeal cancer and may provide prognostic information beyond tumour-node-metastasis staging.","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"935-945"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148368737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0