Eoin F Cleere, Justin M Hintze, Akash N Ramesh, Isobel O'Riordan, Conrad V I Timon, John Kinsella, Paul Lennon, Conall W R Fitzgerald
{"title":"The association of frailty with morbidity following surgical tracheostomy.","authors":"Eoin F Cleere, Justin M Hintze, Akash N Ramesh, Isobel O'Riordan, Conrad V I Timon, John Kinsella, Paul Lennon, Conall W R Fitzgerald","doi":"10.1017/S0022215125000246","DOIUrl":"10.1017/S0022215125000246","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to assess whether frailty (measured using the 5-Item Modified Frailty Index) was associated with increased morbidity following surgical tracheostomy.</p><p><strong>Methods: </strong>A single-centre retrospective cohort study analysed a prospectively maintained database between 2022 and 2023. Univariable and multivariable regressions were used to determine factors (including frailty) associated with increased morbidity.</p><p><strong>Results: </strong>A total of 174 patients underwent surgical tracheostomy in the study period with 28 patients determined as frail (16.1 per cent). Overall, 21 patients (12.1 per cent) suffered a tracheostomy-specific complication. Multivariable regression found an association between frail patient status and increased tracheostomy-specific complications (odds ratio 4.09, 95 per cent confidence interval 1.51-11.11; <i>p</i> = 0.006) and longer hospital length of stay (β 15.76 days, 95 per cent confidence interval 1.06-30.44; <i>p</i> = 0.036).</p><p><strong>Conclusion: </strong>Frailty was associated with increased morbidity and longer hospital stay following tracheostomy. Assessment of frailty may guide decision making and patient discussions when planning tracheostomy.</p>","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"738-744"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143719831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The saccule and gravity.","authors":"Hiroaki Ichijo, Hisako Ichijo","doi":"10.1017/S0022215125102600","DOIUrl":"10.1017/S0022215125102600","url":null,"abstract":"<p><strong>Background: </strong>The important role of the saccule is the sensing of gravity. In other words, gravity always stimulates the macula of the saccule.</p><p><strong>Objectives: </strong>The aim of this study was to clarify whether nystagmus and dizziness occur by intentional changes upon stimulation to the saccules.</p><p><strong>Methods: </strong>The subjects were eight healthy humans. Experiment 1: Subjects were asked to maintain a supine position to check for nystagmus and dizziness. Experiment 2: Subjects were asked to tilt their heads 45º to the left in the supine position to check for nystagmus and dizziness. Experiment 3: Subjects were asked to maintain a left-ear-down 90º position to check for nystagmus and dizziness.</p><p><strong>Results: </strong>In all the experiments, no one revealed nystagmus and no one complained of dizziness.</p><p><strong>Conclusion: </strong>Neither nystagmus nor dizziness occurs by intentional changes in the stimulation to the saccules.</p>","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"718-722"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144368986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chang Woo Lee, Wei Jia, Roanna Norman, Alex Dando, Susan Swain, Francesca Hilder, Maxine Flubacher, Joseph Davies, Oliver Donnelly, Jon Bird, Neil De Zoysa, Emma King
{"title":"Oncological and functional outcomes for transoral robotic surgery versus radiotherapy in T1-2 N0-1 p16+ oropharyngeal carcinoma.","authors":"Chang Woo Lee, Wei Jia, Roanna Norman, Alex Dando, Susan Swain, Francesca Hilder, Maxine Flubacher, Joseph Davies, Oliver Donnelly, Jon Bird, Neil De Zoysa, Emma King","doi":"10.1017/S0022215125000350","DOIUrl":"10.1017/S0022215125000350","url":null,"abstract":"<p><strong>Objectives: </strong>Oncological and functional outcomes for T1-2 N0-1 (TNMv8) p16-positive oropharyngeal squamous cell carcinoma patients were analysed according to treatment: either transoral robotic surgery (TORS) (Surgery group - TORS and neck dissection ± adjuvant radiotherapy/chemoradiotherapy) or primary radiotherapy/chemoradiotherapy (Oncology group).</p><p><strong>Methods: </strong>Single-centre retrospective observational study.</p><p><strong>Results: </strong>The two-year disease-free survival rate was 88 per cent for the Oncology group (n = 42) and 95 per cent for the Surgery group (n = 44). The two-year overall survival rate was 98 per cent for the Oncology group and 100 per cent for the Surgery group. The functional swallowing outcome at two years post-treatment was similar in both groups. Subgroup analysis showed patients treated with surgery-only with no adjuvant treatment had the best functional outcome whilst patients treated with surgery and post-operative chemoradiotherapy had the worst functional outcome.</p><p><strong>Conclusion: </strong>The overall oncological and functional outcomes at two years were similar in both groups. Patients treated with surgery-only had the best functional outcome without compromised oncological outcome.</p>","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"730-737"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Louay Salfity, George McNally, Bertie Fernando, Anu Daudia
{"title":"Endoscopic dacryocystorhinostomy: a retrospective study of our experience.","authors":"Louay Salfity, George McNally, Bertie Fernando, Anu Daudia","doi":"10.1017/S0022215125102508","DOIUrl":"10.1017/S0022215125102508","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to assess the surgical and patient reported outcomes for monocanalicular and bicanalicular silicone stent insertion in endoscopic dacryocystorhinostomy for distal nasolacrimal duct obstruction.</p><p><strong>Methods: </strong>A retrospective cohort study was undertaken for all endoscopic dacryocystorhinostomy cases performed collaboratively by ENT and ophthalmology at Royal Blackburn Hospital.</p><p><strong>Results: </strong>A total of 60 patients were included in the study. Tubes were used in 95 per cent of cases; 92 per cent reported a positive outcome. Minor post-operative complications occurred in 30 per cent. When further broken down by tube type, success rates were 94 per cent for monocanalicular and 95.5 per cent for bicanalicular stents, however, the difference was not statistically significant. In contrast, the complication rates were 22 per cent for monocanalicular stents and 63.6 per cent for bicanalicular stents, with this difference being statistically significant.</p><p><strong>Conclusion: </strong>Both monocanalicular and bicanalicular stents showed similar high surgical success rates. However, monocanalicular stents were better tolerated by patients and associated with fewer complications.</p>","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"696-699"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Radiomics in vestibular schwannomas, misplaced electrode arrays in cochlear implant surgery and local anaesthetic Eustachian tube balloon dilatation.","authors":"Jonathan Fishman","doi":"10.1017/S0022215125102880","DOIUrl":"https://doi.org/10.1017/S0022215125102880","url":null,"abstract":"","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":"139 8","pages":"645-646"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The characteristic of conventional and extended high-frequency audiometry in older adults - a community-based investigation in South China.","authors":"Qiyang Sun, Mengqi Zhao, Xiaomei Sun, Yanfeng Deng, Yuzhi Zhang, Guanxia Xiong, Fanqin Wei","doi":"10.1017/S0022215125000489","DOIUrl":"10.1017/S0022215125000489","url":null,"abstract":"<p><strong>Objectives: </strong>To define extended high-frequency hearing threshold ranges in normal hearing elderly (aged 55 years and above) and identify associated risk factors for extended high-frequency hearing loss.</p><p><strong>Methods: </strong>Pure-tone thresholds (0.25-16 kHz) and word recognition scores were measured using portable audiometric equipment. Lifestyle and medical histories were collected, and generalised linear models analysed risk factors for extended high-frequency hearing (10-12 kHz).</p><p><strong>Results: </strong>In normal hearing elderly (28 ears, 18 subjects), 95 per cent confidence intervals for 10 and 12 kHz were 34.770-49.301 and 56.976-65.809, respectively. Among 342 ears (200 subjects), hypertension emerged as a leading risk factor for extended high-frequency hearing loss, while lipid-lowering medications showed potential protective effects.</p><p><strong>Conclusion: </strong>Preliminary extended high-frequency hearing thresholds were established, with hypertension identified as a key risk factor and lipid-lowering medications as a potential protective factor.</p>","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"687-695"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xueqian Yang, Liang Peng, Ruihua Fang, Lin Chen, Zhangwei Hu, Dan Wang, Renqiang Ma, Jie Deng, Xiaolin Zhu, Zhangfeng Wang, Weiping Wen, Wenbin Lei, Wei Sun
{"title":"Retrospective analysis of 351 patients with vocal fold leukoplakia: impact of smoking, lesion size and histopathological grade on treatment outcomes.","authors":"Xueqian Yang, Liang Peng, Ruihua Fang, Lin Chen, Zhangwei Hu, Dan Wang, Renqiang Ma, Jie Deng, Xiaolin Zhu, Zhangfeng Wang, Weiping Wen, Wenbin Lei, Wei Sun","doi":"10.1017/S0022215125103058","DOIUrl":"10.1017/S0022215125103058","url":null,"abstract":"<p><strong>Objective: </strong>To explore the treatment options and prognostic factors of vocal fold leukoplakia.</p><p><strong>Methods: </strong>The study examined conservative and surgical treatment approaches, and analysed prognostic factors influencing vocal fold leukoplakia outcomes.</p><p><strong>Results: </strong>In the conservative treatment group, lesion size (<i>p</i> = 0.035) and smoking (<i>p</i> < 0.001) were identified as independent factors influencing treatment outcomes. In the surgical treatment group, lesion size (<i>p</i> = 0.018) was identified as an independent factor affecting recurrence. There was no statistically significant difference in the effectiveness of conservative versus surgical treatment for patients with hyperplasia (<i>p</i> = 0.223), mild dysplasia (<i>p</i> = 0.634) and moderate dysplasia (<i>p</i> = 0.758).</p><p><strong>Conclusion: </strong>Smoking and lesion size are key factors influencing the outcome of conservative treatment, while lesion size is a significant factor affecting recurrence in surgically treated patients. More importantly, conservative treatment should be prioritised for patients with moderate dysplasia and milder vocal fold leukoplakia.</p>","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"1-7"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zachary Chu, Chen Zhang, Enoch Kwok, Yaoyi Ng, Tony Tang, Song Tar Toh, Shaun Loh, John Loh
{"title":"Hypoglossal nerve stimulation explantation in patients with obstructive sleep apnoea: a systematic review.","authors":"Zachary Chu, Chen Zhang, Enoch Kwok, Yaoyi Ng, Tony Tang, Song Tar Toh, Shaun Loh, John Loh","doi":"10.1017/S0022215124001646","DOIUrl":"10.1017/S0022215124001646","url":null,"abstract":"<p><strong>Objective: </strong>Hypoglossal nerve stimulation has emerged as a promising therapeutic approach for obstructive sleep apnoea patients who are intolerant to continuous positive airway pressure therapy. This paper aimed to explore reasons for hypoglossal nerve stimulation device explantation and associated complications.</p><p><strong>Methods: </strong>Following Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines, a systematic search across Embase Ovid, PubMed, Scopus, and the Cochrane library yielded 14 articles that met the inclusion criteria. Exclusion criteria were (1) systematic reviews and meta-analyses, conference posters and editorials; (2) non-English studies; and (3) studies published before 2010.</p><p><strong>Results: </strong>Of the 121 patients identified as having undergone hypoglossal nerve stimulation device explantation, 126 reasons were identified for the procedure. The primary reasons included device malfunction (19.8 per cent), infection (19.0 per cent) and device migration (18.3 per cent). Other reasons included discomfort (9.5 per cent), improper placement (6.3 per cent) and ineffective devices (6.3 per cent). Complications were infrequent (2.48 per cent).</p><p><strong>Conclusion: </strong>Device malfunction, infection and device migration were prominent reasons for hypoglossal nerve stimulation device explantation. Complications post-explantation were rare but included temporary hypoglossal paresis.</p>","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"655-662"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142502190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emre Orhan, Serdar Can Güven, Recep Karamert, Zafer Günendi, Bülent Gündüz
{"title":"A new perspective on primary Sjogren's syndrome: investigation of vestibular and balance functions.","authors":"Emre Orhan, Serdar Can Güven, Recep Karamert, Zafer Günendi, Bülent Gündüz","doi":"10.1017/S0022215125000647","DOIUrl":"10.1017/S0022215125000647","url":null,"abstract":"<p><strong>Objectives: </strong>Sjogren's syndrome is a chronic inflammatory condition with an autoimmune history that primarily affects women in middle age (male to female ratio is 1:9). This study aims to evaluate the functional balance status of the patients in primary Sjogren's syndrome and to examine their peripheral and central vestibular functions.</p><p><strong>Methods: </strong>A total of 24 patients with primary Sjogren's syndrome and 26 sex-matched controls were included in this study. Gaze, saccade, tracking, optokinetic, video head impulse and sensory organisation tests were performed on the participants.</p><p><strong>Results: </strong>Significant decreases were observed in video head impulse and sensory organisation tests in participants with Sjogren's syndrome compared to controls.</p><p><strong>Conclusion: </strong>This study documented the findings of patients with Sjogren's syndrome from a vestibular and balance perspective. The study's findings have guided relevant professionals in the follow-up of patients with Sjogren's syndrome to improve patients' daily life, balancing performance and quality of life.</p>","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"707-712"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144333283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Omidvari, Alimohamad Asghari, Mohsen Ahadi, Ahmad Daneshi, Zahra Azad
{"title":"Vestibular dysfunction and hearing outcome in idiopathic sudden sensorineural hearing loss.","authors":"Ali Omidvari, Alimohamad Asghari, Mohsen Ahadi, Ahmad Daneshi, Zahra Azad","doi":"10.1017/S0022215125000672","DOIUrl":"10.1017/S0022215125000672","url":null,"abstract":"<p><strong>Objective: </strong>To describe vestibular dysfunction accompanied by sudden sensorineural hearing loss and explore its potential prognostic role.</p><p><strong>Methods: </strong>A total of 44 Idiopathic Sudden Sensorineural Hearing loss cases were enrolled. Pure tone audiometry (PTA) was performed at the first visit and three months after standard therapy. Patients' improvement and severity of hearing loss were categorised based on Siegel and American Speech and Hearing Association criteria. Their recovery rate and factors affecting recovery were explored.</p><p><strong>Results: </strong>The mean age of the participants was 52.1 years. The caloric and cervical vestibular-evoked myogenic potential test abnormalities were detected in 36.4 and 31.8 per cent of participants. Vertigo was present in 36.4 per cent at the first visit. Based on American Speech and Hearing Association criteria, 16 patients experienced at least 1 grade improvement to a less severe hearing loss status at the follow up. A total of 31.7 per cent of patients demonstrated complete or partial recovery. Vestibular dysfunction was associated with poorer PTA results.</p><p><strong>Conclusion: </strong>Abnormal caloric and cervical vestibular-evoked myogenic potential tests, as well as the presence of vertigo, can indicate more profound inner-ear damage.</p>","PeriodicalId":16293,"journal":{"name":"Journal of Laryngology and Otology","volume":" ","pages":"713-717"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144484758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}