Journal of Medical Case Reports最新文献

{"title":"Extreme compensatory dilatation of the splanchnic artery caused by congenital coarctation of the abdominal aorta: a case report.","authors":"Zhiwei Zhong, Weimin Zhou","doi":"10.1186/s13256-025-05282-3","DOIUrl":"10.1186/s13256-025-05282-3","url":null,"abstract":"<p><strong>Background: </strong>Coarctation of the aorta is a congenital cardiovascular anomaly characterized by aortic narrowing, typically presenting in early life. This report describes an exceptionally rare case of severe abdominal aortic coarctation with extensive collateral vessel formation in an asymptomatic 80-year-old male, underscoring the importance of recognizing delayed presentations and compensatory mechanisms. This report describes a case of severe abdominal aortic narrowing and significant compensatory dilatation of visceral arteries in an elderly male, along with a review of pertinent literature.</p><p><strong>Case presentation: </strong>An 80-year-old Han Chinese male with a 10-year history of hypertension controlled with medical management (maximum blood pressure 150/90 mmHg) was incidentally diagnosed with near-occlusion of the upper abdominal aorta during routine physical examination. Computed tomography angiography revealed severe stenosis of the abdominal aorta measuring 7 mm in diameter at its narrowest segment, accompanied by marked compensatory dilatation of the superior mesenteric, inferior mesenteric, and celiac arteries (maximum diameter: 1.4 cm), forming extensive collaterals. Physical examination showed preserved dorsalis pedis pulses and no symptoms of ischemia. Given his asymptomatic status, advanced age, and robust collateral circulation, conservative management with ongoing surveillance was pursued.</p><p><strong>Conclusion: </strong>This case illustrates the potential for advanced coarctation of the aorta to remain asymptomatic in elderly patients owing to compensatory vascular adaptation. It highlights the need for heightened clinical suspicion in patients with hypertension and individualized management strategies balancing risks of intervention against natural history.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"221"},"PeriodicalIF":0.9,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12070760/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heterotopic ossification following total wrist arthroplasty: a case report.","authors":"Sonja Verena Schmidt, Jannik Hinzmann, Maximilian Völlmecke, Christoph Wallner, Marcus Lehnhardt, Patrick Simon Harenberg","doi":"10.1186/s13256-025-05258-3","DOIUrl":"https://doi.org/10.1186/s13256-025-05258-3","url":null,"abstract":"<p><strong>Background: </strong>Total wrist arthroplasty as a procedure in patients with advanced osteoarthritis has gained more popularity in recent years. As early implants had high rates of complications and newer implants have only slowly gained traction, some sequelae have not been reported yet.</p><p><strong>Case presentation: </strong>This study presents the case of a male German patient, 57 years old, with advanced osteoarthritis who received arthroplasty and presented with severely restricted range of motion 6 weeks after surgery. Radiographs revealed signs of heterotopic ossification that could be confirmed during the revision surgery. Intraoperatively, ossifications were removed and the mobile parts of the implant were changed. In the further course of the healing process, no further signs of ossifications have been reported for 1 year, but range of motion remains reduced.</p><p><strong>Conclusion: </strong>This is the first reported case of heterotopic ossification of the wrist following arthroplasty. Heterotopic ossification should be taken into consideration in cases of restricted range of motion after arthroplasty to be able to handle this complication adequately.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"215"},"PeriodicalIF":0.9,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12067731/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Managing pseudophakic bullous keratopathy with a topical rho kinase inhibitor: a case series.","authors":"Nir Erdinest, Nadav Shemesh, Yishay Weill, Shani Morad, Itay Nitzan, David Smadja, David Landau, Itay Lavy","doi":"10.1186/s13256-025-05263-6","DOIUrl":"https://doi.org/10.1186/s13256-025-05263-6","url":null,"abstract":"<p><strong>Background: </strong>Cataract surgery is common procedure globally. Among its adverse effects is pseudophakic bullous keratopathy (PBK), a corneal disorder characterized by stromal edema and the formation of epithelial and subepithelial bullae due to endothelial cell loss and decompensation. This case series examines the outcomes of using the topical Rho kinase inhibitor Ripasudil for managing pseudophakic bullous keratopathy (PBK) in three patients treated at Hadassah Medical Center. Clinical data, including visual acuity, intraocular pressure, central corneal thickness (CCT), and endothelial cell count, were extracted from electronic medical records before and after treatment. Patients were treated with topical Ripasudil for periods ranging from three to eleven months, three times daily, with adjustments based on disease severity.</p><p><strong>Case presentation: </strong>The first case involved a 66-year-old Jewish female, who presented with persistent corneal edema in the left eye. Following three months of Ripasudil therapy, the patient exhibited notable improvement in best-corrected visual acuity (BCVA), a reduction in central corneal thickness (CCT), and decreased central stromal edema. Similarly, the second case featured a 58-year-old Jewish male with a history of cataract surgery in the right eye performed 3 years prior at an external institution. After 3 months of Ripasudil treatment, the patient demonstrated measurable improvements in both BCVA and CCT, mirroring the therapeutic trend observed in the first case. In parallel, the third case described a 69-year-old Jewish male who presented with a 6-month history of blurred vision. In total, 11 months of Ripasudil administration led to resolution of stromal haze and corneal edema, along with a significant reduction in CCT and an enhancement in BCVA.</p><p><strong>Conclusion: </strong>These findings suggest that Ripasudil has potential as an effective treatment option for PBK, possibly delaying or avoiding the need for corneal transplantation. Further studies are required to confirm the long-term efficacy and safety of Ripasudil for PBK.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"214"},"PeriodicalIF":0.9,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12060286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chilblain-like lesion associated with coronavirus disease 2019 vaccine in tropical country: a case report.","authors":"Wasuchon Chaichan, Mati Chuamanochan, Pongsak Mahanupab, Siri Chiewchanvit, Napatra Tovanabutra","doi":"10.1186/s13256-025-05254-7","DOIUrl":"https://doi.org/10.1186/s13256-025-05254-7","url":null,"abstract":"<p><strong>Background: </strong>Chilblains have emerged as a cutaneous manifestation following coronavirus disease 2019 vaccination. While there are many case reports on chilblain-like lesions, documentation from tropical countries remains limited. In this context, we report a case detailing chilblain-like lesions associated with coronavirus disease 2019 vaccination in Thailand.</p><p><strong>Case presentation: </strong>A 35-year-old Thai female patient presented with several painful, red papules on the fingers and toes 9 days after receiving the mRNA-1273 vaccination. Skin biopsy was performed, and the results were consistent with chilblains. Laboratory workup revealed positive result for lupus anticoagulant. The rash completely resolved without any treatment but reappeared following the second vaccine dose.</p><p><strong>Conclusion: </strong>Chilblain-like lesion following coronavirus disease 2019 vaccination is frequently observed in temperate countries, with few reports from tropical areas. The presence of lupus anticoagulant may contribute to the development of chilblains after coronavirus disease 2019 vaccination.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"213"},"PeriodicalIF":0.9,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057029/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BRAF mutation in five cases of sinonasal ameloblastic tumors and their clinical course: a case report.","authors":"Mioko Matsuo, Ryosuke Kuga, Tomomi Manako, Kazuki Hashimoto, Ryunosuke Kogo, Masanobu Sato, Takashi Nakagawa","doi":"10.1186/s13256-025-05224-z","DOIUrl":"https://doi.org/10.1186/s13256-025-05224-z","url":null,"abstract":"<p><strong>Background: </strong>Sinonasal ameloblastic tumors exhibit unique clinical, pathological, and genetic traits distinct from mandibular bone cases, accounting for the majority of ameloblastic tumors. Recent findings emphasize a notable genetic disparity, showing high BRAF mutation rates in mandibular cases versus very low rates in maxillary cases.</p><p><strong>Case presentation: </strong>We analyzed five sinonasal ameloblastic tumor cases treated at Kyushu University Hospital. All patients were Japanese, four male and one female, and their age ranged from 43 to 73 years. Three were diagnosed with ameloblastoma, with one experiencing recurrence that progressed to a life-threatening condition owing to the lack of effective treatment. One patient was histologically diagnosed as ameloblastic carcinoma, and another patient, although histologically diagnosed as ameloblastoma, presented with lymph node metastasis, confirming it as a metastasizing ameloblastoma with clinical malignancy. Local radical resection was performed in all five patients; however, three of them had positive resection margins, and two received postoperative (chemotherapy) radiation therapy. Recurrence was confirmed in two patients, with one patient undergoing chemoradiation therapy and achieving local control. BRAF mutations were detected in only one patient.</p><p><strong>Conclusion: </strong>Owing to anatomical challenges in achieving negative resection margins and the low BRAF mutation frequency, sinonasal ameloblastic tumors exhibit poor prognosis with high recurrence, malignancy, and metastasis rates. When factors predicting recurrence post-radical resection in these tumors are identified, chemoradiation therapy is recommended as an adjuvant postoperative treatment. However, it should be noted that this presentation of adjuvant therapy is based on the experience of only five cases.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"210"},"PeriodicalIF":0.9,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital mesenteric absence of mid-gut with ileal volvulus: a case report.","authors":"Jin-Shan Zhang","doi":"10.1186/s13256-025-05260-9","DOIUrl":"https://doi.org/10.1186/s13256-025-05260-9","url":null,"abstract":"<p><strong>Background: </strong>Transmesenteric hernia caused by mesenteric defects are rare causes of intestinal obstruction in children. Here, we report a rare mesenteric defect, which was completely mesenteric in absence, with the defect extending from the mesenteric root to the ascending colon.</p><p><strong>Case presentation: </strong>A 4-year-old Han Chinese boy presented to the surgical emergency department with a 1-day history of abdominal pain and vomiting. An X-ray examination of the abdomen revealed intestinal obstruction. The patient was diagnosed with intestinal obstruction and was advised to undergo laparoscopy. Laparoscopy revealed a large mesenteric defect, with the defect extending from the mesenteric root to the ascending colon, and a single mesenteric vessel supplied the small intestine. The single mesenteric vessel passed along the small intestine and crossed with the distal ileum, which trapped the distal ileum, leading to intestinal obstruction. During surgery, the distal ileum was transected and reanastomosed in front of the mesenteric vessel to relieve the intestinal obstruction, and the mesenteric defect was closed to prevent mesenteric hiatal hernia. There was no recurrence of intestinal obstruction during the follow-up.</p><p><strong>Conclusions: </strong>A complete mesenteric defect with ileal volvulus is a rare cause of intestinal obstruction. Prompt exploration based on clinical signs is mandatory to establish the diagnosis and provide immediate therapy. This can reduce morbidity and mortality in this rare life-threatening disease.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"212"},"PeriodicalIF":0.9,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital scrotal agenesis with bilateral cryptorchidism: a case report.","authors":"Mohammad Sharif Sediqi, Abdulwali Wali, Khatera Habib, Khesrow Ekram, Abdulhai Wali","doi":"10.1186/s13256-025-05218-x","DOIUrl":"10.1186/s13256-025-05218-x","url":null,"abstract":"<p><strong>Background: </strong>The disorder known as congenital scrotal agenesis is an extremely rare condition. In the literature, 11 cases of congenital scrotal agenesis or absence have been reported thus far. Most of them are bilateral and contain cryptorchidism. In a rare case of bilateral cryptorchidism, we report a 36-day-old Afghan infant who presented to Maiwand Teaching Hospital with fever and vomiting due to infection and congenital scrotal agenesis. The diagnosis of these anomalies was made using clinical and laboratory results, with the clinical characteristics being recorded during the sixth week of life. After receiving therapy for sepsis, he was referred to the pediatric surgical department in good health. Given that the parents of the congenital scrotal agenesis reference case were consanguineous, there may have been a genetic component to the development of the condition.</p><p><strong>Case presentation: </strong>We describe a rare instance of bilateral cryptorchidism, with congenital scrotal agenesis in a 36-day-old Afghan baby that had come to Maiwand teaching hospital for fever and vomiting on the basis of sepsis. The clinical characteristics were noted during the sixth week of life and clinical and laboratory results were used to determine the diagnosis of these anomalies. He was referred to the pediatric surgery department in good health following the treatment for sepsis. Given that the reference case of congenital scrotal agenesis had consanguineous parents, a link to genetics may have contributed to the disease's emergence.</p><p><strong>Conclusion: </strong>Congenital scrotal agenesis is an incredibly uncommon condition of urological congenital disorder. To date, the literature has reported 11 cases of congenital scrotal agenesis or absence, most of which are bilateral and involve cryptorchidism. This case presents another human being that suffers congenitally from scrotal agenesis with bilateral cryptorchidism who was born in Kabul city of Afghanistan from a multigravida mother who has positive consanguinity to her husband.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"211"},"PeriodicalIF":0.9,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12056986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise hemodynamic evaluation in the management of dasatinib-related pulmonary arterial hypertension: a case report.","authors":"Shuhei Yamashita, Takahiro Hiraide, Yasuyuki Shiraishi, Yoshinori Katsumata, Masaharu Kataoka, Shogo Fukui, Michiyuki Kawakami, Shinsuke Yuasa, Shinichiro Okamoto, Keiichi Fukuda, Masaki Ieda","doi":"10.1186/s13256-025-05221-2","DOIUrl":"https://doi.org/10.1186/s13256-025-05221-2","url":null,"abstract":"<p><strong>Background: </strong>Dasatinib-related pulmonary arterial hypertension is a rare complication of chronic therapy for hematological malignancies. Pulmonary hypertension often persists despite drug discontinuation and might require vasodilators. Normalizing pulmonary hemodynamics and avoiding the long-term use of vasodilators is challenging.</p><p><strong>Case presentation: </strong>Patient was a 55-year-old Japanese man complaining of progressive dyspnea on effort and fatigue. He had a history of hypertension and chronic myeloid leukemia treated with dasatinib. He was diagnosed with dasatinib-related pulmonary arterial hypertension by a right heart catheterization at rest, demonstrating a mean pulmonary artery pressure of 31 mmHg and a normal pulmonary arterial wedge pressure of 6 mmHg. Symptoms and hemodynamics significantly improved after the discontinuation of dasatinib and the initiation of upfront combination therapy of vasodilators. An exercise right heart catheterization, performed more than 2 years after the initiation of vasodilators, showed a mean pulmonary artery pressure of 15 mmHg at rest and 29 mmHg at peak exercise (normal reference value, < 30 mmHg), suggesting normal pulmonary microcirculation. On the basis of these findings, pulmonary vasodilators were discontinued. Notably, a repeat exercise right heart catheterization demonstrated preserved pulmonary microcirculation, and the patient has remained asymptomatic for more than 2 years after discontinuing pulmonary-arterial-hypertension-targeted therapy.</p><p><strong>Conclusions: </strong>The evaluation of pulmonary microcirculation by exercise right heart catheterization can be useful for withdrawing pulmonary vasodilators safely in the management of patients with dasatinib-related pulmonary arterial hypertension.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"209"},"PeriodicalIF":0.9,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12054259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The application of metagenomic next generation sequencing in diagnosing tuberculous otitis media: a case report and review of the literature.","authors":"HongYan Liu, YiFan Zhu, YangYiYi Huang, Hua Jiang","doi":"10.1186/s13256-025-05257-4","DOIUrl":"https://doi.org/10.1186/s13256-025-05257-4","url":null,"abstract":"<p><strong>Background: </strong>Tuberculous otitis media is a chronic Mycobacterium tuberculosis infection of the middle ear tissues. Diseases with varied and insidious clinical features can make diagnosis difficult and delay treatment.</p><p><strong>Case presentation: </strong>Here, we document a case of tuberculous otitis media in a 46-year-old ethnic Han woman that manifested as nonspecific chronic otitis media. A mastoidectomy and tympanoplasty were performed for the initial diagnosis of cholesteatoma. The histopathology of the tissue specimen revealed granuloma formation with necrosis. Staining for acid-fast bacilli and the polymerase chain reaction method for Mycobacterium tuberculosis yielded negative results. However, the chest computed tomography scan demonstrated a pulmonary miliary nodule. Next, metagenomic next-generation sequencing was applied and the Mycobacterium tuberculosis was identified. The patient recovered after receiving antituberculous treatment.</p><p><strong>Conclusion: </strong>This report highlights the application of novel diagnostic tools such as metagenomic next-generation sequencing as a supplementary method for the diagnosis of tuberculous otitis media in highly suspected patients.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"207"},"PeriodicalIF":0.9,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phosphaturic mesenchymal tumor of the skull base presenting with tumor-induced osteomalacia and multiple fractures: a case report.","authors":"He Zhiqing, Wang Keshuang, Zhang Minghui, Qin Jiace, Qiu Qianhui","doi":"10.1186/s13256-025-05244-9","DOIUrl":"https://doi.org/10.1186/s13256-025-05244-9","url":null,"abstract":"<p><strong>Background: </strong>This case reports a rare disease in which the clinical symptoms are completely inconsistent with the primary site. As the occurrence of this disease is partly rare, the challenges in the diagnosis of phosphaturic mesenchymal tumors are discussed. It also provides a new clinical treatment option, that is, the combined treatment with anlotinib capsules after surgery and the long-term follow-up to observe the effect of the combined treatment.</p><p><strong>Case presentation: </strong>A 27-year-old Chinese woman presented with generalized pain and multiple fractures for 2 years. The present case was initially thought to be hematogenous and involved a malignant predisposition. After initial positron emission tomography-computed tomography imaging, endoscopic resection of the lesion was performed, and a biopsy confirmed the diagnosis of phosphaturic mesenchymal tumor. Following pathological confirmation, the patient was treated with anlotinib capsules. Post-treatment, the patient regained the ability to walk. The patient was monitored for 2 years, during which time no recurrence was observed.</p><p><strong>Conclusions: </strong>Phosphaturic mesenchymal tumors include rare cranial base neoplasms that are often overlooked due to their nonspecific symptoms. Accurate diagnosis requires a comprehensive assessment, encompassing systemic evaluation, laboratory tests, imaging studies, and microscopic examination. This case demonstrates the innovative use of anlotinib capsules in the treatment of PMTs. After 2 years, no recurrence was observed, and the patient returned to normal life. Effective management of this condition necessitates a multidisciplinary approach involving otolaryngologists, radiologists, nuclear medicine specialists, and pathologists.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"208"},"PeriodicalIF":0.9,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}