Journal of Medical Case Reports最新文献

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Seizures Secondary to Aconitum Plant Poisoning: a case report. 乌头中毒致癫痫1例。
IF 0.8
Journal of Medical Case Reports Pub Date : 2026-10-16 DOI: 10.1186/s13256-026-06571-1
Zhijie Zhao, Jiabi Zhang, Juan Du, Luhuan Liu, Guosheng Rao, Manhong Zhou
{"title":"Seizures Secondary to Aconitum Plant Poisoning: a case report.","authors":"Zhijie Zhao, Jiabi Zhang, Juan Du, Luhuan Liu, Guosheng Rao, Manhong Zhou","doi":"10.1186/s13256-026-06571-1","DOIUrl":"10.1186/s13256-026-06571-1","url":null,"abstract":"<p><strong>Background: </strong>Aconitum plant poisoning typically manifests as isolated early cardiotoxicity or late neurotoxicity. However, the dynamic temporal evolution from arrhythmia-driven cardiogenic syncope to true epileptic seizures mediated by direct central nervous system injury remains rarely documented and poorly characterized.</p><p><strong>Case presentation: </strong>We report a 53-year-old Han Chinese male who presented with ventricular tachycardia rapidly degenerating into ventricular fibrillation and cardiac arrest following ingestion of homemade Aconitum kusnezoffii (caowu)-infused liquor. Initial convulsions were tightly coupled with malignant arrhythmias, consistent with cardiogenic syncope. After successful resuscitation, hemoperfusion, and restoration of stable sinus rhythm, the patient developed breakthrough generalized tonic-clonic seizures on hospital days 4-6. Electroencephalography performed during sedation withdrawal revealed bilateral occipital spike-and-slow and sharp-and-slow waves with focal epileptiform discharges, confirming direct central nervous system neurotoxicity rather than recurrent cardiac ischemia. A mechanism-based, staged treatment strategy was employed: early advanced cardiac life support and hemoperfusion targeted cardiotoxicity, while sodium valproate and acetylglutamine were administered for antiepileptic prophylaxis and neuroprotection. The patient was discharged on day 13; antiepileptic therapy was successfully tapered and discontinued at 3 months without seizure recurrence, with normalization of electroencephalography and electrocardiography.</p><p><strong>Conclusions: </strong>This case provides the first systematic documentation, validated by electroencephalography, of the transition from cardiogenic convulsions to true epileptic seizures in Aconitum alkaloid poisoning. The findings highlight the critical role of pharmacokinetic-driven central nervous system retention in delayed seizure onset and underscore the necessity of prolonged neurological monitoring, early electroencephalography evaluation for late-onset convulsions, and sustained antiepileptic prophylaxis to reduce mortality and long-term neurological sequelae.</p><p><strong>Key clinical message: </strong>Aconitum plant poisoning may manifest as early cardiogenic syncope and convulsions secondary to malignant arrhythmias, progressing in the late stage to genuine seizures caused by central nervous system (CNS) injury. Effective management requires a staged treatment strategy targeting both cardiotoxicity and neurotoxicity, with a focus on stabilizing cardiac rhythm and providing neuroprotection as needed.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"20 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13675999/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149207026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multimodal imaging features of nuclear protein in testis carcinoma of the submandibular gland: a case report. 颌下腺睾丸癌核蛋白的多模态影像特征1例。
IF 0.8
Journal of Medical Case Reports Pub Date : 2026-10-16 DOI: 10.1186/s13256-026-06615-6
Yanan Shi, Da Shi, Dan Luo, Yongzhou Xu
{"title":"Multimodal imaging features of nuclear protein in testis carcinoma of the submandibular gland: a case report.","authors":"Yanan Shi, Da Shi, Dan Luo, Yongzhou Xu","doi":"10.1186/s13256-026-06615-6","DOIUrl":"10.1186/s13256-026-06615-6","url":null,"abstract":"<p><strong>Rationale: </strong>NUT carcinoma (NC) is a rare and highly aggressive malignancy defined by rearrangements of the NUTM1gene. Primary NC of the submandibular gland is exceptionally rare, with nonspecific imaging features that often lead to misdiagnosis as common salivary gland tumors and delayed treatment.</p><p><strong>Patient concerns: </strong>A 32-year-old man presented with a painless mass in the left submandibular region that rapidly enlarged from 2 cm to approximately 4 cm within 1 month, accompanied by the development of ipsilateral pharyngeal and periauricular pain.</p><p><strong>Diagnoses: </strong>Preoperative multimodal imaging-computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography/computed tomography (PET/CT)-revealed an ill-defined, invasive mass with heterogeneous enhancement and intense metabolic activity (SUVmax 18.4). The diagnosis was confirmed by histopathological examination and immunohistochemical analysis, which demonstrated diffuse nuclear positivity for NUT protein.</p><p><strong>Interventions: </strong>The patient underwent radical surgical resection (left neck dissection), followed by adjuvant chemotherapy and radiotherapy.</p><p><strong>Outcomes: </strong>No evidence of local recurrence or metastatic disease was observed on follow-up imaging at 9 months postoperatively.</p><p><strong>Lessons: </strong>This case underscores that although the imaging features of submandibular gland NC are not pathognomonic, the combination of a rapidly growing invasive mass, heterogeneous enhancement, and marked hypermetabolism should raise clinical suspicion. Prompt biopsy with NUT immunohistochemical testing is essential for definitive diagnosis and early intervention, which is critical given the tumor's highly aggressive nature.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"20 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13675987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149207065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Integrated physical, cognitive and psychological rehabilitation following multiple ACL reconstructions in a professional handball player: a case report. 职业手球运动员多次前交叉韧带重建后的综合身体、认知和心理康复一例报告。
IF 0.8
Journal of Medical Case Reports Pub Date : 2026-10-13 DOI: 10.1186/s13256-026-06732-2
Marc Niering, Jana Goldstein, Rainer Beurskens, Elisa Ueding, Johanna Seifert
{"title":"Integrated physical, cognitive and psychological rehabilitation following multiple ACL reconstructions in a professional handball player: a case report.","authors":"Marc Niering, Jana Goldstein, Rainer Beurskens, Elisa Ueding, Johanna Seifert","doi":"10.1186/s13256-026-06732-2","DOIUrl":"10.1186/s13256-026-06732-2","url":null,"abstract":"<p><strong>Background: </strong>Anterior cruciate ligament (ACL) injuries with repeated surgical interventions and postoperative complications pose a major challenge in sports rehabilitation. Beyond neuromuscular deficits, psychological and cognitive readiness often remain impaired, increasing reinjury risk and threatening athletic careers. This case highlights an integrated rehabilitation strategy addressing physical, psychological, and cognitive domains in a professional athlete with a complex surgical history.</p><p><strong>Case presentation: </strong>A 31-year-old white Serbian male professional handball player with a history of two ACL reconstructions, meniscal repairs, a postoperative knee infection, and multiple arthroscopic interventions presented with persistent knee instability, pain, and psychological distress. Following repeated failed return-to-play attempts, he underwent a ten-week intervention combining therapeutic exercises, sports psychology sessions, and neurocognitive dual-task training. Pre- and post-intervention assessments included gait analysis, postural control, strength testing, ACL-specific functional tests, and psychological evaluations. Post-intervention assessments showed improvements in gait mechanics, postural stability, neuromuscular strength, and reduced functional asymmetries, alongside lower cognitive anxiety and greater motivation.</p><p><strong>Conclusions: </strong>This case suggests that an interdisciplinary, multimodal rehabilitation approach, integrating physical, psychological, and cognitive strategies, may help address both physical deficits and psychological barriers in athletes with multiple ACL surgeries and complex postoperative courses. Such integration may support function, confidence, and readiness in high-performance athletes facing career-threatening injuries.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"20 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13663265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149182451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A changing of the guard, continuity of purpose: the enduring importance of case reports at the Journal of Medical Case Reports. 换岗,目的延续:《医学病例报告杂志》病例报告的持久重要性。
IF 0.8
Journal of Medical Case Reports Pub Date : 2026-10-12 DOI: 10.1186/s13256-026-06718-0
Richard A Rison
{"title":"A changing of the guard, continuity of purpose: the enduring importance of case reports at the Journal of Medical Case Reports.","authors":"Richard A Rison","doi":"10.1186/s13256-026-06718-0","DOIUrl":"10.1186/s13256-026-06718-0","url":null,"abstract":"<p><p>As I take on the role of Editor-in-Chief of Journal of Medical Case Reports (JMCR), I do so with gratitude and with no wish to reinvent a journal whose founding purpose remains sound: publishing peer-reviewed case reports that add clinically meaningful knowledge while protecting the people whose experiences make those reports possible. In this editorial, I look back at JMCR's origins under Michael Kidd and place the former Cases Journal and CasesDatabase initiatives in their historical context. I also reaffirm the journal's commitments to written consent for publication, CARE-compliant reporting, scientific rigor, clinical education, and accountable human editorial judgment. The current Springer Nature/BMC environment offers new ways to extend the educational life of published reports through the updated website, selected Cases of the Month, Springer Nature Research Communities, JMCR Clinical Minute, JMCR: Clinical Reasoning From Case Reports, Correspondence, and responsible social dissemination. Programs already active are distinguished from those still being developed or planned. The principle is straightforward: new formats should serve the carefully reviewed case report, never displace it.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"20 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13660000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149169586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bone marrow edema of the femoral head treated with extracorporeal magnetotransduction therapy and conservative management: a case series. 体外磁导疗法治疗股骨头骨髓水肿及保守治疗:一个病例系列。
IF 0.8
Journal of Medical Case Reports Pub Date : 2026-10-10 DOI: 10.1186/s13256-026-06661-0
Elizabeth Bondi, Martin Ringeisen, Lennart Gerdesmeyer
{"title":"Bone marrow edema of the femoral head treated with extracorporeal magnetotransduction therapy and conservative management: a case series.","authors":"Elizabeth Bondi, Martin Ringeisen, Lennart Gerdesmeyer","doi":"10.1186/s13256-026-06661-0","DOIUrl":"10.1186/s13256-026-06661-0","url":null,"abstract":"<p><strong>Background: </strong>Bone marrow edema of the hip is a painful condition that can significantly impair function and may lead to more serious joint problems if left untreated. Extracorporeal magnetotransduction therapy (EMTT) is an innovative non-invasive treatment that shows promise in orthopedic applications. However, its use has not been documented for treating bone marrow edema. This case series describes two patients with femoral head bone marrow edema in whom clinical symptoms and radiological findings improved following EMTT given alongside conservative treatment.</p><p><strong>Case presentations: </strong>We report on two German male patients, aged 44 and 55, who presented with an acute onset of hip pain lasting four weeks, with no history of trauma. Both patients exhibited reduced hip mobility, and magnetic resonance imaging (MRI) scans confirmed bone marrow edema in the femoral head. Each patient underwent eight sessions of EMTT over four weeks (10,000 pulses, 8 Hz, intensity level 8), alongside standard conservative treatments, which included medication, physiotherapy and, in one patient, partial off-loading. At follow-up appointments (13 weeks and 9 weeks post-consultation, respectively), both patients reported complete pain relief and regained their range of motion. MRI results confirmed near-complete resolution of the edema in both cases.</p><p><strong>Conclusion: </strong>In both patients, symptoms and MRI findings improved following EMTT administered together with conservative treatment, and the treatment was well tolerated. Considering the small number of patients, the concurrent interventions and the self-limiting natural history of bone marrow edema, a causal contribution of EMTT cannot be established from these observations. The favorable course nevertheless supports the formal evaluation of EMTT in this indication, and randomized controlled trials are needed to determine its efficacy in bone marrow edema.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"20 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13654217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149167155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing sexual exposure to oxaliplatin in vaginal secretions during FOLFOX chemotherapy: a case report. 评估FOLFOX化疗期间阴道分泌物中奥沙利铂的性暴露:一个病例报告。
IF 0.8
Journal of Medical Case Reports Pub Date : 2026-10-09 DOI: 10.1186/s13256-026-06169-7
Katherine Bolten, Lisa Bleyle, Andrea DeBarber, Abigail Liberty
{"title":"Assessing sexual exposure to oxaliplatin in vaginal secretions during FOLFOX chemotherapy: a case report.","authors":"Katherine Bolten, Lisa Bleyle, Andrea DeBarber, Abigail Liberty","doi":"10.1186/s13256-026-06169-7","DOIUrl":"10.1186/s13256-026-06169-7","url":null,"abstract":"<p><strong>Background: </strong>Sexual health is increasingly relevant to survivorship care among people with cancer. There is little quantitative data to inform the risk of exposure to chemotherapeutics during sex with someone receiving chemotherapy.</p><p><strong>Case presentation: </strong>A 54-year-old non-Hispanic white woman with Stage IIIA rectal cancer self-collected vaginal swabs and urine for 5 consecutive days during two cycles of chemotherapy. Swabs and urine were tested for intact oxaliplatin levels using hydrophilic interaction liquid chromatography (HILIC). Urine oxaliplatin levels peaked on the first day after chemotherapy and remained detectable for up to 3 days. The vaginal swab oxaliplatin levels exhibited significant degradation with freezing. Repeat testing revealed improved recovery with polysorb rather than cotton swabs. Polysorb vaginal swabs detected oxaliplatin only on day 1 after chemotherapy. On this day, the level of oxaliplatin remained at the limit of detection. Conservatively accounting for lost sample during freezing (50%) and assuming detection at the upper end of the limit of detection, we estimate that a vaginal swab could contain up to 2.5 ng of oxaliplatin chemotherapy on the first day after chemotherapy. Oxaliplatin levels from vaginal swab remained below the limit of detection thereafter.</p><p><strong>Conclusions: </strong>This is the first study to report that oxaliplatin levels in vaginal swabs are highest the first day after chemotherapy and undetectable thereafter. These data suggest that there is some indication for abstinence or barriers such as condoms in the immediate period after receipt of chemotherapy to reduce partner exposure during intercourse. The findings and methods reported inform future studies that seek to integrate patient-centered outcomes such as partner chemotherapy exposure into survivorship care.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"20 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13653412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149148260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Probable vestibular paroxysmia mimicking benign paroxysmal positional vertigo of the superior semicircular canal in the presence of a neurovascular conflict: a case report and review of the literature. 在神经血管冲突的情况下,可能的前庭阵发性眩晕模仿良性阵发性半圆形管位置性眩晕:一个病例报告和文献回顾。
IF 0.8
Journal of Medical Case Reports Pub Date : 2026-10-07 DOI: 10.1186/s13256-026-06552-4
Quentin Legois, Laurent Tremelet, Pauline Nieto, Salim Ismail, Mikhael Makhoul, Charles-Edouard Molinier, Olivier Deguine, Mathieu Marx
{"title":"Probable vestibular paroxysmia mimicking benign paroxysmal positional vertigo of the superior semicircular canal in the presence of a neurovascular conflict: a case report and review of the literature.","authors":"Quentin Legois, Laurent Tremelet, Pauline Nieto, Salim Ismail, Mikhael Makhoul, Charles-Edouard Molinier, Olivier Deguine, Mathieu Marx","doi":"10.1186/s13256-026-06552-4","DOIUrl":"10.1186/s13256-026-06552-4","url":null,"abstract":"<p><strong>Background: </strong>Positional vertigo is a frequent complaint in otology and vestibular physiotherapy, arising from functional or structural causes affecting the peripheral or central vestibular systems. Although benign paroxysmal positional vertigo (BPPV) is the most common form, other etiologies such as vestibular paroxysmia (VP), central positional vertigo, or vertebrobasilar insufficiency should be considered. Recognizing the specific features and differential diagnosis of these conditions is crucial for accurate assessment.</p><p><strong>Case presentation: </strong>We describe the case of a 52-year-old French woman presenting with positional vertigo initially diagnosed as a BPPV of the right superior semicircular canal. Despite multiple repositioning maneuvers, symptoms persisted. The positional downbeat and right torsional nystagmus observed in the right Dix-Hallpike test (illustrated in video) and the lack of response to treatment raised suspicion of an atypical etiology. MRI re-evaluation revealed a neurovascular conflict between the right anterior inferior cerebellar artery and the right vestibulocochlear nerve, supporting the diagnosis of probable vestibular paroxysmia mimicking a superior canal BPPV.</p><p><strong>Conclusions: </strong>Positional vertigo resembling BPPV that is refractory to repositioning maneuvers or atypical should prompt reconsideration of the diagnosis. In particular, suspected superior canal BPPV requires heightened diagnostic caution and a comprehensive clinical assessment.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"20 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13653408/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149148383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fetal hemothorax due to intrapleural rupture of a small anterior thoracic lymphatic malformation: a case report. 胸膜内破裂致小胸前淋巴畸形胎儿血胸1例。
IF 0.8
Journal of Medical Case Reports Pub Date : 2026-10-05 DOI: 10.1186/s13256-026-06618-3
Haruna Kawaguchi, Katsuya Hirata, Wakako Ichida, Sayaka Fukuda, Masahiro Zenitani, Naruhiko Takahashi, Shusaku Hayashi
{"title":"Fetal hemothorax due to intrapleural rupture of a small anterior thoracic lymphatic malformation: a case report.","authors":"Haruna Kawaguchi, Katsuya Hirata, Wakako Ichida, Sayaka Fukuda, Masahiro Zenitani, Naruhiko Takahashi, Shusaku Hayashi","doi":"10.1186/s13256-026-06618-3","DOIUrl":"10.1186/s13256-026-06618-3","url":null,"abstract":"<p><strong>Background: </strong>Fetal pleural effusion is usually chylous, whereas hemothorax is considerably rarer. Trauma, iatrogenic complications, and rupture of intrathoracic tumors have been reported as causes of fetal hemothorax. Lymphatic malformations often enlarge during the fetal period; however, these benign lesions may regress spontaneously after birth or be managed with sclerotherapy. Accurate prenatal diagnosis is therefore crucial for determining whether fetal intervention or postnatal management is the most appropriate strategy. Here, we present a rare case of a fetus with hemothorax presumably caused by the rupture of a small anterior chest wall lymphatic malformation that progressed to hydrops fetalis.</p><p><strong>Case presentation: </strong>A Japanese woman in her 30 s (gravida 2, para 1) was referred at 26 weeks of gestation after bloody pleural fluid was obtained by thoracentesis at another hospital. On admission, ultrasonography showed right pleural effusion without ascites or subcutaneous edema. Additionally, there was a small heterogeneous echogenic region in the anterior chest wall without detectable blood flow, although its clinical significance was initially unclear. Fetal magnetic resonance imaging demonstrated pleural fluid with signal characteristics consistent with hemothorax and identified a small anterior chest wall cystic lesion, suggestive of a lymphatic malformation. Because the pleural effusion was hemorrhagic, thoracoamniotic shunting was avoided owing to concerns regarding rebleeding and potential worsening of fetal anemia. At 27 weeks and 6 days, an emergency cesarean section was performed for worsening hydrops. The infant required immediate intubation, chest drainage, and blood transfusion. Postnatal imaging confirmed an anterior chest wall lymphatic malformation extending toward the mediastinum. The lesion did not require surgical or sclerosing therapy and showed spontaneous regression during follow-up. Neurodevelopmental assessment was within the normal range at a corrected age of 18 months.</p><p><strong>Conclusion: </strong>This case demonstrated the importance of detailed imaging studies, including magnetic resonance imaging, for the diagnosis of pleural effusion and small anterior chest lesions. In cases of tumor-associated fetal hemothorax caused by benign lesions such as lymphatic malformations, early delivery followed by neonatal management may represent a reasonable alternative to fetal intervention.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"20 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13644158/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149127810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Severe upper limb soft tissue infection with compartment syndrome following a scratch injury: a case report. 抓伤后严重上肢软组织感染伴筋膜室综合征1例报告。
IF 0.8
Journal of Medical Case Reports Pub Date : 2026-09-30 DOI: 10.1186/s13256-026-06651-2
Alexander Blümke, Suna Brunnemer, Frederik Weil, João Pinheiro, Frederic Bludau, Michael Hackl, Sascha Gravius, Ali Darwich
{"title":"Severe upper limb soft tissue infection with compartment syndrome following a scratch injury: a case report.","authors":"Alexander Blümke, Suna Brunnemer, Frederik Weil, João Pinheiro, Frederic Bludau, Michael Hackl, Sascha Gravius, Ali Darwich","doi":"10.1186/s13256-026-06651-2","DOIUrl":"https://doi.org/10.1186/s13256-026-06651-2","url":null,"abstract":"<p><strong>Background: </strong>Phlegmon is a severe skin and soft tissue infection (SSTI) that can escalate rapidly if not promptly recognized and treated. Its early presentation may appear deceptively mild, potentially delaying recognition of its severity. Without timely intervention, phlegmon can extend into deeper tissues and result in life-threatening systemic complications. Although SSTIs are common, progression from a seemingly minor scratch injury to a fulminant upper extremity infection complicated by compartment syndrome and multiorgan failure is uncommon. This case is reported to highlight the potential severity of such presentations and the importance of early recognition and intervention.</p><p><strong>Case presentation: </strong>We present the case of a 58-year-old German female teacher who developed a severe left upper extremity SSTI following a minor scratch injury sustained from a student. Despite initial conservative management with antibiotic therapy, the condition progressed to severe phlegmon with compartment syndrome, culminating in sepsis and multiorgan failure characterized by acute renal failure, disseminated intravascular coagulation (DIC), and early liver failure. Urgent surgical intervention was required, including fasciotomy, surgical debridement, and multiple revision procedures. Microbiological cultures initially identified Streptococcus pyogenes (Group A). During the later course of treatment, Pseudomonas aeruginosa was detected in revision samples. Empirical intravenous antibiotic therapy with Meropenem was initiated and subsequently adjusted to Ampicillin/Sulbactam according to microbiological findings. The patient required hemodialysis because of acute renal failure but gradually recovered, allowing discontinuation of dialysis. At follow-up, the infection had resolved and the skin grafts demonstrated satisfactory healing; however, significant functional deficits persisted despite intensive rehabilitation.</p><p><strong>Conclusion: </strong>This case underscores the critical importance of early diagnosis and aggressive multidisciplinary management in preventing severe complications associated with SSTIs. Furthermore, it highlights that seemingly minor skin injuries may progress to compartment syndrome and life-threatening systemic complications. Early recognition, prompt surgical intervention, and coordinated multidisciplinary care were essential for successful infection control and limb preservation.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"20 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13628932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Foreign body ingestion: how common is it really? A review and our experience managing a young woman: a case report. 异物摄入:到底有多普遍?回顾和我们处理一名年轻女性的经验:一份病例报告。
IF 0.8
Journal of Medical Case Reports Pub Date : 2026-09-23 DOI: 10.1186/s13256-026-06167-9
Manoj Yadav, Nasreen Hanifa, P Hemantha Kumar
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