Journal of Medical Case Reports最新文献

{"title":"An interdisciplinary approach for the management of periapical lesion using regenerative approach: a case report.","authors":"Priyanka Jaiswal, Sakshi Vishal Kotecha, Shweta Bhagat, Shweta Sedani, Akash Thakare","doi":"10.1186/s13256-025-05380-2","DOIUrl":"10.1186/s13256-025-05380-2","url":null,"abstract":"<p><strong>Background: </strong>Periapical lesions are common sequelae of endodontic infections, often presenting as chronic apical periodontitis. These lesions result from the microbial invasion of the root canal system, leading to inflammation and subsequent bone resorption. While conventional root canal therapy is the primary treatment modality, it occasionally fails to resolve periapical pathology. In such cases, surgical intervention becomes necessary.</p><p><strong>Case presentation: </strong>This report presents the case of a 32-year-old female of Indian ethnicity with chief complaints of pain and pus discharge in the upper right front area in the past 2 months. Radiographic findings were evident, depicting periapical radiolucency. Upon debriding the lesion, it was observed to be creamish with irregular shape and size and, hence, it was sent for histopathological analysis. It was inferred to be a dental cyst associated with the right upper front region of the jaw.</p><p><strong>Conclusion: </strong>This case report pinpoints the importance of considering the diagnosis of periapical lesions. It also adds to the point of treatment plan that can be followed as a multidisciplinary approach to challenging periapical lesions.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"333"},"PeriodicalIF":0.9,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cervical giant Nabothian cysts in a woman with primary infertility: a case report.","authors":"Sedigheh Hosseini, Parisa Taherzadeh Boroujeni, Nazanin Hajizadeh, Mahsa Kazemi, Leila Majdi, Hamidreza Mosleh","doi":"10.1186/s13256-025-05393-x","DOIUrl":"10.1186/s13256-025-05393-x","url":null,"abstract":"<p><strong>Background: </strong>Nabothian cysts are benign cervical lesions commonly observed in women of reproductive age, typically ranging from 2 to 10 mm in diameter and often asymptomatic. These cysts arise from the obstruction of cervical mucous glands, a phenomenon frequently linked to childbirth, minor trauma, or chronic cervicitis. While small Nabothian cysts are usually incidental findings, giant Nabothian cysts-those exceeding 4 cm-are rare and can present diagnostic and therapeutic challenges. Their size and appearance may mimic malignant entities such as adenoma malignum, necessitating advanced imaging and histopathological evaluation. Although their association with infertility remains controversial, some evidence suggests that large cysts might interfere with fertility by obstructing the cervical canal or altering mucus production, which is critical for sperm transport. This report examines a rare case of giant Nabothian cysts in the context of assisted reproductive technology, highlighting their management and potential implications for infertility treatment.</p><p><strong>Case presentation: </strong>A 41-year-old Iranian woman with a 2-year history of primary infertility presented to our clinic. She reported regular menstrual cycles and no symptoms such as pelvic pain or abnormal discharge. During her infertility evaluation, transvaginal ultrasonography identified multiple large cervical cysts (20-45 mm) obstructing the cervical os. Subsequent magnetic resonance imaging and biopsy confirmed these as benign Nabothian cysts. Her partner's semen analysis revealed severe teratozoospermia, prompting the use of intracytoplasmic sperm injection. During oocyte retrieval, the cysts were aspirated to prevent potential complications during embryo transfer. Two high-quality embryos were transferred, but the cycle did not result in pregnancy. Cytological analysis of the aspirated fluid reaffirmed the benign nature of the cysts.</p><p><strong>Conclusion: </strong>This case demonstrates that giant Nabothian cysts can be safely aspirated during an assisted reproductive technology cycle, potentially improving procedural outcomes. However, the lack of pregnancy suggests that, while cyst management may address mechanical barriers, it does not guarantee success in multifactorial infertility cases. Further studies are needed to elucidate the role of Nabothian cysts in infertility and refine their management in assisted reproductive technology settings.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"332"},"PeriodicalIF":0.9,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Renal cell carcinoma accompanied by aldosterone-secreting contralateral adrenal metastasis: a case report.","authors":"Modar Doyya, Ghina Alloush, Mazen Alloush","doi":"10.1186/s13256-025-05396-8","DOIUrl":"10.1186/s13256-025-05396-8","url":null,"abstract":"<p><strong>Background: </strong>Kidney cancer is a highly prevalent malignancy, consistently ranking among the top ten cancers affecting both men and women, and its mortality has been increasing globally. Renal cell carcinoma is the most common type and has a tendency to metastasize, with a predilection for spreading to other organs. While the adrenal gland is located adjacent to the kidney, metastasis of renal cell carcinoma to the adrenal gland is considered rare compared with other sites such as the lungs, liver, and bones. In addition, the occurrence of metastasis to the contralateral adrenal gland is an exceedingly rare phenomenon.</p><p><strong>Case presentation: </strong>A 57-year-old Arabic female patient presented with intermittent hematuria over a period of several months. The patient's medical and surgical history revealed no significant findings. Laboratory tests revealed normal results, with the exception of elevated aldosterone levels and a high aldosterone renin ratio, despite a normal blood pressure reading. Further investigations revealed the coexistence of renal cell carcinoma and adrenal adenoma on the left side, along with adrenal mass on the right side, which confirmed its metastatic nature after resection and pathological study. As a result, a left nephrectomy and right adrenalectomy were subsequently conducted. Postsurgery, the aldosterone level normalized, confirming the secretory function of the metastasized renal carcinoma in the right adrenal gland.</p><p><strong>Conclusion: </strong>The secretion of aldosterone from an adrenal metastasis arising from renal cell carcinoma is a rare phenomenon that healthcare providers should bear in mind during differential diagnosis. It is imperative to conduct thorough investigations and extended research to understand the potential complications associated with this unique presentation.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"331"},"PeriodicalIF":0.9,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239418/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acquired appendiceal-cecal fistula as a complication of untreated acute appendicitis in a noncompliant patient: a case report.","authors":"Mohammad AshrafAzimi, Abbas Abdollahi, Amir Rahmanian Sharifabad, Seyed Hassan Seyed Sharifi, Ali Mehri, Seyed Ramin Dabiri","doi":"10.1186/s13256-025-05382-0","DOIUrl":"10.1186/s13256-025-05382-0","url":null,"abstract":"<p><strong>Background: </strong>Appendiceal fistula is a primary appendix perforation into the surrounding hollow viscera or skin and can rarely occur as a complication of appendicitis. To date, only nine cases of appendiceal fistula to the cecum have been reported.</p><p><strong>Case presentation: </strong>We present the case of a 30-year-old Persian male who presented with a low-grade fever and lower abdominal pain for 3 days. He had a history of untreated acute appendicitis 3 years prior. During the appendectomy, a fistula between the appendix and cecum, along with a thick cecal wall, was found. The patient underwent a right hemicolectomy and was discharged with a diagnosis of appendiceal-cecal fistula in the context of appendicitis.</p><p><strong>Conclusion: </strong>An appendiceal-cecal fistula usually does not cause any specific symptoms and is an accidental finding. Surgeons should thoroughly explore the ileocecal region for the fistula, particularly in patients with a history of untreated appendicitis. Although the appendiceal-cecal fistula is a rare finding, it can change the surgical plan. Therefore, it is important to discuss this complication with the patient and obtain informed consent preoperatively to avoid potential medicolegal issues. On the basis of our experience, right hemicolectomy is associated with a good surgical outcome in managing the fistula, especially when malignancy is suspected.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"328"},"PeriodicalIF":0.9,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complexities of care in a pediatric patient with epidermolysis bullosa acquisita and duchenne muscular dystrophy: a case report.","authors":"Khayry Al-Shami, Ziad Haddad, Malath Mohammad Yousef Abuelrub, Basel Adnan Adel Qaddoumi, Falah Qudah, Tala Abdelaziz Abdullateef Shandaq, Manar Al-Shami, Saja Karaja","doi":"10.1186/s13256-025-05395-9","DOIUrl":"10.1186/s13256-025-05395-9","url":null,"abstract":"<p><strong>Background: </strong>Type VII collagen autoantibodies drive epidermolysis bullosa acquisita (EBA), a rare autoimmune blistering disorder. While typically seen in adults, pediatric cases-especially those with additional comorbidities-present unique clinical challenges.</p><p><strong>Case presentation: </strong>We describe a rare and diagnostically complex case of a 5-year-old Jordanian female with a history of epidermolysis bullosa and Duchenne muscular dystrophy (DMD), an X-linked disorder predominantly affecting males; the diagnosis of DMD in our patient was based on historical clinical and biopsy findings, as genetic confirmation was unavailable owing to the external nature of the original diagnosis. She presented with extensive blistering, chronic wounds, recurrent infections, and profound metabolic disturbances, including severe electrolyte imbalances and liver dysfunction. The coexistence of EBA and DMD introduces unique diagnostic uncertainties, necessitating a multidisciplinary approach incorporating advanced wound care, infection prevention, nutritional support, and genetic counseling.</p><p><strong>Conclusion: </strong>This case represents one of the few documented reports of EBA co-occurring with DMD in a female patient, highlighting critical gaps in understanding its pathophysiologic interactions. The complex disease interplay exacerbates systemic complications, demanding a highly individualized and interdisciplinary care strategy. Recognizing atypical DMD presentations and refining diagnostic criteria for such rare coexisting conditions are essential. Additionally, streamlining management approaches and providing robust education and support for affected families remain crucial.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"330"},"PeriodicalIF":0.9,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ruptured heterotopic pregnancy with successful term intrauterine pregnancy outcome after natural conception: a case report.","authors":"Hassen Mohammed Areys, Mahamed Sheikahmed Abdi, Nour Hies Omer, Osman Ali Osman, Tariku Mulatu Bore","doi":"10.1186/s13256-025-05392-y","DOIUrl":"10.1186/s13256-025-05392-y","url":null,"abstract":"<p><strong>Background: </strong>Heterotopic pregnancy is the simultaneous existence of intrauterine and extrauterine pregnancies. This is a rare obstetric case, with an incidence of 1 in 30,000 in naturally conceived pregnancies and 1 in 100 pregnancies achieved through in vitro fertilization. Early diagnosis of heterotopic pregnancy is challenging in developing countries with no high-resolution ultrasound.</p><p><strong>Case presentation: </strong>A 22-year-old multigravida Somali mother presented to our hospital on her tenth week of gestation with the complaint of progressively worsening abdominal pain of 7 days' duration. The patient had type III female genital mutilation at the age of 7 years. The patient presented with tachycardia, but her overall hemodynamic status remained stable. Obstetric ultrasound showed a right-sided adnexal mass, a hemoperitoneum, and an intrauterine pregnancy at 10 weeks + 2 days of gestation. Two units of screened, cross-matched whole blood were prepared, and the patient underwent an exploratory laparotomy. Intraoperative findings revealed a right-sided ruptured tubal ectopic pregnancy at the ampulla with active bleeding, a hemoperitoneum of approximately 900 mL with clots, and a bulky uterus about 10 weeks in size with a normal left tube and ovary. The patient had a brisk recovery postoperatively, and the intrauterine pregnancy was conservatively monitored until term gestation. An alive female neonate weighing 3000 gm was delivered via spontaneous vertex delivery with an Apgar score of 8 and 9 in the first and fifth minutes, respectively.</p><p><strong>Conclusion: </strong>Heterotopic pregnancy is a rare obstetric condition that can occur through natural conception. Female genital mutilation might be an independent risk factor for heterotopic pregnancy that occurs via natural conception. The presence of an intrauterine gestation does not rule out a concomitant extrauterine gestation, so a high index of suspicion and timely diagnosis should be made for a pregnant woman presenting with acute abdominal pain and an adnexal mass. A routine early-first-trimester antenatal ultrasound scan of the adnexa by an experienced obstetrician or sonographer is paramount to obtaining an accurate and timely diagnosis.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"329"},"PeriodicalIF":0.9,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A left-sided incarcerated Amyand hernia in a 4-month-old male infant: a case report.","authors":"Roya Golmoradi Pilehroud, Alireza Ziyabakhsh, Keyvan Amini, Reza Panahizadeh, Mohammadamin Vatankhah, Hamed Mohammadi Haris","doi":"10.1186/s13256-025-05394-w","DOIUrl":"10.1186/s13256-025-05394-w","url":null,"abstract":"<p><strong>Background: </strong>Amyand hernias are inguinal hernias that involve the vermiform appendix and are very rare. Left-sided Amyand hernias are even rarer, and their diagnosis is often made intraoperatively.</p><p><strong>Case presentation: </strong>In this article, we report a case of left-sided Amyand hernia in a 4-month-old Persian male infant. He presented with left groin swelling, which extended to his left scrotum. He had suffered from a reducible left-sided inguinal hernia since he was 3 months old, which was no longer reducible in this episode. The diagnosis of left-sided Amyand hernia was made intraoperatively, and appendectomy, cecum reduction, and herniorrhaphy were performed.</p><p><strong>Conclusion: </strong>The best approach for treating Amyand hernias without appendicitis is controversial, and each approach has advantages and disadvantages; however, if there is acute appendicitis, appendectomy is recommended.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"324"},"PeriodicalIF":0.9,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236001/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144591405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute fatty liver disease in full-term pregnancy: a case report and review of the literature.","authors":"Phuc Nhon Nguyen, Quang Nhat Ho","doi":"10.1186/s13256-025-05362-4","DOIUrl":"10.1186/s13256-025-05362-4","url":null,"abstract":"<p><strong>Background: </strong>Cases of acute fatty liver of pregnancy are extremely rare but represent a serious complication as a life-threatening condition for both the mother and newborn in late-term pregnancy. Preoperatively, adequate management with multidisciplinary teams and timely delivery are potentially required to save materno-fetal life. Herein, we report a rare, inconspicuous case of acute fatty liver of pregnancy in third-trimester pregnancy and a review of the literature to underscore this hazardous entity.</p><p><strong>Case presentation: </strong>A 28 year-old pregnant Vietnamese woman was transferred to our tertiary referral hospital for suspicion of acute fatty liver of pregnancy without prodromal signs, except for intermittent abdominal pain at 39 weeks 3 days of gestational age. In accordance with the Swansea criteria, laboratory findings contributed to confirming the diagnosis of acute fatty liver of pregnancy. Immediately, an emergent cesarean section was rapidly performed. Postoperatively, the patient recovered gradually with rapid improvement of biochemical and hematological parameters. The woman and her neonate were discharged uneventfully after 9 days of hospitalization.</p><p><strong>Conclusions: </strong>Acute fatty liver of pregnancy may be asymptomatic and can progress quickly, affecting multiple organs. Early diagnosis is based on abnormal presentation of serum laboratory tests. In addition, clinicians ought to assess the diagnosis following the Swansea criteria. Importantly, supportive therapy, strict monitoring, and early termination of pregnancy, when appropriate, are still the mandatory protocols for the management of acute fatty liver of pregnancy.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"326"},"PeriodicalIF":0.9,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239470/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144591455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cholecystoduodenal fistula presenting with refractory upper gastrointestinal bleeding: retrospective analysis: a case report.","authors":"Zhen Zhao, Zihao Fan, Tianpeng Zhang","doi":"10.1186/s13256-025-05297-w","DOIUrl":"10.1186/s13256-025-05297-w","url":null,"abstract":"<p><strong>Background: </strong>Spontaneous cholecystoduodenal fistula presents an uncommon complication arising from cholelithiasis. Its symptoms are typically nonspecific and can closely mimic those of other chronic biliary diseases, therefore increasing the likelihood of misdiagnosis. Massive upper gastrointestinal bleeding complicated with cholecystoduodenal fistula is an extremely rare condition with only a few documented cases.</p><p><strong>Case presentation: </strong>Here we discuss the case of a 77-year-old Han Chinese female who presented with refractory upper gastrointestinal bleeding due to a cholecystoduodenal fistula. The patient was diagnosed through a comprehensive analysis of using computed tomography, esophagogastroduodenoscopy, contrast‑enhanced ultrasound, and endoscopic retrograde cholangiopancreatography. Additionally, we present a literature review and retrospective study to provide further context and insights into this rare condition. Given the rarity and diagnostic challenges of cholecystoduodenal fistula presenting primarily with upper gastrointestinal bleeding, we conducted a retrospective analysis of cases diagnosed at our institution over the past two decades. Only four cases (including the current one) manifested with gastrointestinal hemorrhage as the initial symptom.</p><p><strong>Conclusions: </strong>Acute upper gastrointestinal bleeding caused by cholecystoduodenal fistula is very challenging to diagnose. Physicians involved in the management of patients with upper gastrointestinal bleeding should consider the possibility of a biliary-enteric fistula as a possible cause, especially in patients with risk factors for gallstone disease. Contrast‑enhanced ultrasound may facilitate prompt diagnosis in such cases.</p><p><strong>Strengths and limitations: </strong>The Beijing Friendship Hospital affiliated with Capital Medical University serves as China's national-level clinical research center for digestive system diseases. Consequently, there is an ample supply of clinical cases even for the rare cholecystoduodenal fistula. Through summarizing the diagnosis, treatment, and outcome of this disease category, it holds the potential to offer valuable support for the future diagnosis and treatment of cholecystoduodenal fistula. Furthermore, we performed a 20-year institutional retrospective analysis of cholecystoduodenal fistula. This systematic review exemplifies our center's clinical expertise in managing this rare condition when it manifests as acute upper gastrointestinal bleeding. While our findings provide valuable insights, the limited cohort size (n = 4) necessitates caution in extrapolating these results to broader populations. Multicenter studies with larger samples are warranted to validate our observations.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"325"},"PeriodicalIF":0.9,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12235799/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144591456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obstructed hemi-vagina and ipsilateral renal anomaly syndrome in Vietnam: an overview from clinical diagnosis approach to management: a case report.","authors":"Huu-Trung Nguyen, Xuan-Hong Tomai","doi":"10.1186/s13256-025-05289-w","DOIUrl":"10.1186/s13256-025-05289-w","url":null,"abstract":"<p><strong>Background: </strong>Obstructed hemi-vagina and ipsilateral renal anomaly syndrome is a rare congenital condition, which is described in a combination of uterus didelphys and obstructed hemi-vagina with ipsilateral renal agenesis. Until now, the diagnosis of this anomaly is challenging as there are diverse symptoms depending on pre-puberty and post-puberty age onset. Early diagnosis of this syndrome allows for improvement of quality of life and prevents fertility-related complications.</p><p><strong>Case report: </strong>We present the case of a 13-year-old Vietnamese girl who was admitted to the emergency department with colicky lower abdominal pain and a tender cystic mass in the left vaginal wall. Her menarche started 6 months ago, and she had an experience of progressive menstruation-related pain. The ultrasound and magnetic resonance imaging identified presence of uterus didelphys, an absence of left kidney associated with a menstrual-blood-retained mass from the uterus cavity to the left side of vagina (hematocolpos). The patient underwent a vaginal excision to drain blood-containing mass and was discharged from hospital 5 days after the operation. The patient and her parents have been provided with a detailed follow-up plan to prevent the complications of renal failure and infertility.</p><p><strong>Conclusion: </strong>The possibility of obstructed hemi-vagina and ipsilateral renal anomaly syndrome should be considered in both pre-puberty and post-puberty girls who present with acute lower abdominal pain. Ultrasound plays a crucial role in making an early diagnosis of this condition, while magnetic resonance imaging allows for classification and prediction of fertility capacity. Vaginal excision is a minimally invasive procedure to relieve the pain and prevent the adverse effects.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"327"},"PeriodicalIF":0.9,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239487/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144591457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}