Journal of lasers in medical sciences最新文献

{"title":"The Efficacy of Various Conditioning Methods in Restoring the Color of White Spot Lesions Through Resin Infiltration.","authors":"Alireza Boruziniat, Farzaneh Ahrari, Hooman Shafaee, Farnoosh Faravani, Abdolrasoul Rangrazi, Farhad Akbari Kamrani, Amir Fallahrastegar","doi":"10.34172/jlms.2025.60","DOIUrl":"https://doi.org/10.34172/jlms.2025.60","url":null,"abstract":"<p><p><b>Introduction:</b> This study aimed to assess the effects of supplemental conditioning methods, including extended etching time, Er,Cr:YSGG laser radiation, and sandblasting, on enhancing the recovery of white spot lesions (WSLs) through resin infiltration. <b>Methods:</b> Seventy premolars were subjected to a cariogenic solution to induce WSLs. Subsequently, the teeth were divided into 5 groups of 14, based on the enamel conditioning protocol applied, as follows: Group 1: Icon-Etch (Control), Group 2: Double Icon-Etch, Group 3: Sandblasting+Icon-Etch, Group 4: Er,Cr:YSGG laser+Icon-Etch, and Group 5: Icon-Etch+Er,Cr:YSGG laser+Icon-Etch. The Er,Cr:YSGG laser (2780 nm) was applied at 0.75 W and 20 Hz. Tooth color was measured initially (T0), after WSL induction (T1), and following resin infiltration (T2). Color changes between treatment stages were compared among the groups. <b>Results:</b> One-way analysis of variance (ANOVA) displayed no significant differences in ΔET0-T1 or ΔET1-T2 between the groups (<i>P</i>>0.05). However, a significant difference was found between the groups in the color change from baseline to post-resin infiltration (ΔET0-T2) (<i>P</i>=0.004). The ΔET0-T2 was significantly lower in groups 4 and 5 compared to the control group and group 3. Group 2 did not demonstrate a significant difference from the other groups (<i>P</i>>0.05). <b>Conclusion:</b> The combination of laser etching and acid etching was effective in enhancing the recovery of WSLs through resin infiltration. The ΔET0-T2 in groups subjected to laser plus acid etching fell below the critical threshold of 3.7 units, indicating that the post-treatment tooth color was not clinically distinguishable from the original tooth color.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"16 ","pages":"e60"},"PeriodicalIF":1.5,"publicationDate":"2025-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12958254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147365515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Periapical Lesion Healing without Root Canal Obturation Associated with Photodynamic Therapy: A Case Report.","authors":"Nazanin Zargar, Navid Nasrabadi, Ghazal Hemmati, Mohadeseh Asgari","doi":"10.34172/jlms.2025.59","DOIUrl":"https://doi.org/10.34172/jlms.2025.59","url":null,"abstract":"<p><p><b>Introduction:</b> Total bacterial disinfection in root canal therapy is challenging due to residual infected dentin, which may harbor bacteria. Photodynamic therapy (PDT) enhances antibacterial efficacy and supplements conventional endodontic treatment. <b>Case Presentation:</b> This case report describes the healing of a large periapical lesion in a 22-year-old male patient with pulp necrosis and a secondary acute apical abscess in the mandibular left incisors. The patient underwent cleaning and shaping of the root canal system, but did not return for obturation. After chemo-mechanical preparation and calcium hydroxide dressing, the patient received PDT using 0.1 mg/mL Toluidine Blue (FotoSan®; CMS Dental, Denmark) and an LED lamp (630 nm, 3 W/cm²). Despite the absence of root canal obturation and delayed treatment, radiographic examination at the 1-year follow-up showed complete healing of the periapical lesion with no symptoms. <b>Conclusion:</b> This unexpected outcome suggests that PDT may improve disinfection and lead to successful treatment even without conventional root canal obturation. PDT, when combined with conventional root canal therapy, may enhance treatment outcomes.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"16 ","pages":"e59"},"PeriodicalIF":1.5,"publicationDate":"2025-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12958266/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147365522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tooth and Composite Discoloration After Photodynamic Therapy with Different Photosensitizers and Cleansers Under Accelerated Aging Conditions.","authors":"Sedighe Sadat Hashemikamangar, Shakiba Farahani, Mahdi Abbasi, Nasim Chiniforush","doi":"10.34172/jlms.2025.58","DOIUrl":"https://doi.org/10.34172/jlms.2025.58","url":null,"abstract":"<p><p><b>Introduction:</b> This study aimed to evaluate tooth and composite discoloration after photodynamic therapy using different concentrations of photosensitizers, combined with various cleaning agents (water, 2.5% sodium hypochlorite and 17% EDTA), immediately and after accelerated aging. <b>Methods:</b> In this <i>in vitro</i> study, 104 bovine maxillary central incisors were selected. Enamel-dentin discs (7×7×2 mm) were prepared from the middle of the crown and subjected to an artificial demineralization and remineralization cycle for 14 days. The samples were divided into 13 groups: Photodynamic therapy using methylene blue or toluidine blue at two concentrations of 50 µg/ml and 100 µg/ml, each with three detergents (water, 2.5% sodium hypochlorite, or 17% EDTA), and a control group: disinfection with chlorhexidine 2%. The surface of the dentin was bonded, and the composite resin was applied. All specimens underwent 100 hours of xenon lamp exposure. Tooth and composite colors were measured at baseline, after photodynamic therapy, and after accelerated aging. Statistical analysis was performed using one-way ANOVA and Tukey's HSD. <b>Results:</b> Color change caused by methylene blue (50 µg/ml) and rinsing with EDTA or sodium hypochlorite was below the perceptibility threshold (ΔE<3.3). According to the Tukey HSD test, no significant difference was observed between this group and the control group (<i>P</i>>0.05). All groups demonstrated clinically perceptible composite discoloration. <b>Conclusion:</b> Tooth discoloration after photodynamic therapy with 50 µg/ml methylene blue and rinsing with EDTA or sodium hypochlorite is not visually detectable. Photodynamic therapy with 100 µg/ml methylene blue or toluidine blue leads to the discoloration of composite restorations.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"16 ","pages":"e58"},"PeriodicalIF":1.5,"publicationDate":"2025-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12958263/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147365487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Low-Level Laser Therapy on Reversal of Soft Tissue Local Anesthesia in Children: A Randomized Clinical Trial.","authors":"Alaa M Eldehna, Amira A Mohamed, Sherine Badawy, Mohammed H Mostafa","doi":"10.34172/jlms.2025.57","DOIUrl":"https://doi.org/10.34172/jlms.2025.57","url":null,"abstract":"<p><p><b>Introduction:</b> Prolonged numbness after local dental anesthesia in children can cause significant discomfort, patient anxiety, and risk of accidental lip or cheek injury, limiting normal eating and speaking. Current reversal approaches may require additional injections and risk side effects, underscoring the need for safer alternatives. Recent advances suggest photobiomodulation (PBM) by low-level laser therapy (LLLT) may accelerate recovery, but clinical data in pediatric dentistry remain limited. <b>Methods:</b> In a randomized clinical trial, 20 children with 40 affected teeth were divided into two groups: Group I received anesthesia with 1:100,000 epinephrine, while Group II received 1:200,000 epinephrine. Using a deactivated laser, a split-mouth design was used to compare the laser-treated and control sides. Anesthesia withdrawal was evaluated at 15-minute intervals following patient-reported resolution of numbness. Data were analysed using a paired t-test. <b>Results:</b> Group I showed statistically significant differences from the control in all parameters except chin and cheek numbness. Group II exhibited statistically significant differences in all parameters except chin and cheek numbness resolution and recovery of normal lip sensation. <b>Conclusion:</b> LLLT at 650 nm accelerated anesthesia withdrawal compared to standard conditions, with enhanced effects observed at higher V.C. concentrations. LLLT effectively reduces anesthesia duration by inducing vasodilation and improving blood flow to the irradiated area.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"16 ","pages":"e57"},"PeriodicalIF":1.5,"publicationDate":"2025-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12958258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147365578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Vibradiofotology Technology using the ERECTOFIX Device in the Treatment of Erectile Dysfunction: A Randomized Controlled Double-Blind Pilot Study.","authors":"Mohammadreza Razzaghi, Morteza Fallah Karkan, Hossein Rahnama, Zahra Razzaghi, Parnia Rahnamay Farnood","doi":"10.34172/jlms.2025.56","DOIUrl":"https://doi.org/10.34172/jlms.2025.56","url":null,"abstract":"<p><p><b>Introduction:</b> Over the past decade, energy-based therapies have been introduced as non-invasive and restorative treatment modalities for erectile dysfunction. Furthermore, previous studies have shown the efficacy of penile vibratory stimulation and photobiomodulation in treating erectile dysfunction. Integrating these therapeutic approaches, which are employed simultaneously in the Vibradiofotology technology, may lead to achieving better outcomes in the treatment of erectile dysfunction. This study aims to evaluate the efficacy of Vibradiofotology technology delivered via the Erectofix device in patients with erectile dysfunction. <b>Methods:</b> In this randomized clinical trial, fifty-five patients diagnosed with erectile dysfunction were included. The patients were assigned to either the control group or the intervention group. In the intervention group, the patients received treatment with the Erectofix device for five sessions. Each session lasted 45 minutes and was administered once a week. Meanwhile, the control group received oral medication along with sham laser treatment. <b>Results:</b> Among the fifty-five patients included in the study, 27 were assigned to the intervention group and 28 to the control group. The intervention group showed a significant improvement in each domain of the IIEF score compared to the control group. The erectile function showed a significantly greater increase in IIEF scores in the intervention group (19.59±5.57) compared to the control group (7.39±2.23; <i>P</i><0.001). Furthermore, significant improvements were observed in orgasmic function, sexual desire, intercourse satisfaction, and overall satisfaction in the intervention group. <b>Conclusion:</b> Vibradiofotology technology, which integrates different therapeutic approaches, may be a safe treatment option for erectile dysfunction. Improvements in IIEF scores, patients' overall satisfaction, and erectile function can be promising in the efficacy of this modality. Nevertheless, due to the limitations of the present study, further research is required to investigate the potential benefits of this novel modality in improving patients' quality of life.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"16 ","pages":"e56"},"PeriodicalIF":1.5,"publicationDate":"2025-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12958276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147365502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Effectiveness of Digitally and Conventionally Fabricated Occlusal Splints with Low-Power Laser Therapy in Treating Temporomandibular Disorders.","authors":"Rahab Ghoveizi, Leili Habibi, Elaheh Beyabanaki, Sara Tavakolizadeh, Hossein Akbari","doi":"10.34172/jlms.2025.55","DOIUrl":"https://doi.org/10.34172/jlms.2025.55","url":null,"abstract":"<p><p><b>Introduction:</b> Temporomandibular disorder (TMD) is common, and occlusal splints (OSs) and low-power laser (LPL) therapy are effective conservative treatments. This study aims to compare the effectiveness of conventionally and digitally fabricated OS, with and without LPL, in treating TMD patients. <b>Methods:</b> Forty patients diagnosed with TMDs were randomly assigned to four treatment groups. The first group received LPL therapy in conjunction with digitally fabricated OS. The second group was treated with LPL therapy and conventionally fabricated OS. The third group received digitally made OS without LPL, and the fourth group was provided with conventionally fabricated OS without LPL. Patients' pain levels were evaluated using a Visual Analog Scale (VAS) before treatment (pre-treatment) and at 1 week, 1 month, and 3 months post-treatment. The Association of Dental Research (IADR) scale was used to measure mouth opening and mandibular movements. Additionally, the physical characteristics of the OS were assessed over the 3-month period, including their resistance to failure, color change, and the level of patient satisfaction with the treatments. <b>Results:</b> There were no statistically significant differences in color change or failure rates between conventionally and digitally fabricated occlusal splints after three months (<i>P</i>>0.05). Likewise, patient satisfaction levels did not differ significantly between the two splint types (<i>P</i>>0.05). However, the conventionally fabricated splints required significantly more adjustment points and a longer delivery time (<i>P</i><0.05). All four treatment groups experienced a significant reduction in pain intensity following the interventions (<i>P</i><0.05). Additionally, the group receiving low-power laser therapy with digitally fabricated splints demonstrated greater improvements in all three movement parameters (<i>P</i><0.05). <b>Conclusion:</b> The use of a combined treatment approach, involving a digitally-fabricated OS and LPL therapy could yield greater benefits for patients with TMDs in terms of pain reduction and functional improvements.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"16 ","pages":"e55"},"PeriodicalIF":1.5,"publicationDate":"2025-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12958260/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147365575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Home-use Photobiomodulation for Pain Management and Recovery after Lower Third Molar Extraction: A Pilot Split-Mouth Study.","authors":"Walid Altayeb, Tosun Tosun, Islam Kassem, Omar Hamadah","doi":"10.34172/jlms.2025.53","DOIUrl":"https://doi.org/10.34172/jlms.2025.53","url":null,"abstract":"<p><p><b>Introduction:</b> The extraction of lower third molars often results in pain, swelling, and trismus, significantly impacting recovery. Conventional pharmacological treatments, though effective, pose risks like systemic side effects. Photobiomodulation (PBM) therapy is a promising non-invasive alternative, known for its anti-inflammatory and healing properties. This study evaluates the efficacy of home-use PBM devices in postoperative recovery, emphasizing accessibility and patient adherence. <b>Methods:</b> A split-mouth pilot study was conducted with 12 participants (18-45 years old) undergoing bilateral third molar extractions. One side was treated with daily PBM therapy using a low-level light device (four wavelengths: 940 nm, 850 nm, 660 nm, 630 nm) for seven days, while the other side served as a placebo. Recovery metrics, including pain (VAS scale), swelling, trismus, and medication use, were assessed daily. Statistical analysis utilized the Kruskal-Wallis and Mann-Whitney U tests. <b>Results:</b> The PBM group showed significantly reduced pain (Day 3: <i>P</i>=0.001), swelling (Day 7: <i>P</i>=0.001), and trismus (Day 4: <i>P</i>=0.037), with sustained improvements through Day 7. Analgesic use was significantly lower in the PBM group (Day 4: <i>P</i>=0.001), demonstrating PBM's analgesic and anti-inflammatory effects. <b>Conclusion:</b> Home-use PBM therapy effectively manages postoperative complications, accelerating recovery and reducing medication dependence. It offers a practical, non-invasive alternative to clinic-based treatments, enhancing accessibility and adherence. Further studies are recommended to validate these findings and optimize PBM protocols.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"16 ","pages":"e53"},"PeriodicalIF":1.5,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12958259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147365577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Er:YAG Laser Versus Conventional Surface Treatment of Lithium Disilicate: In Vitro Study.","authors":"Cesar Manuel Poquioma Choque, Rodolfo Calle-Chavez, Fabricio Hinojosa Pedraza, Katherine Joselyn Atoche-Socola","doi":"10.34172/jlms.2025.54","DOIUrl":"https://doi.org/10.34172/jlms.2025.54","url":null,"abstract":"<p><p><b>Introduction:</b> The high-power 2940 nm Er:YAG (erbium-doped yttrium aluminium garnet) laser increases the rough surface of lithium disilicate, increasing the bonding strength of ceramics when they are bonded to the tooth using resin matrix cement. This investigation aimed to compare the Er:YAG laser with the conventional surface treatment of lithium disilicate. <b>Methods:</b> In this study, 50 lithium disilicate discs (5 mm diameter×2 mm thickness) were divided into five groups (n=10): Control group (CG) (10% hydrofluoric acid followed by 37% phosphoric acid), Group 1 (G1) (ER:YAG laser energy of 300 mJ/50 µs), Group 2 (G2) (Er:YAG laser energy of 400 mJ/50 µs), Group 3 (G3) (Er:YAG laser energy of 500 mJ/50 µs), and Group 4 (G4) (10% hydrofluoric acid, Er:YAG laser energy of 500 mJ/50 µs). After completing the surface treatments, 6 mm high Tygon was fixed and filled with self-adhesive dual resin cement (SET PP SDI Limited, Victoria, Australia). The samples were stored for 24 hours and subjected to shear tests until structural failure. <b>Results:</b> ANOVA analysis found no statistically significant difference between the groups analyzed (<i>P</i>=0.0689). G2 had the highest bond strength with 12.6±3.2 MPa, while G1 had the lowest with 9.5±2.2 MPa, followed by the CG 9.8±3.2. It was observed that with higher laser irradiation power, the adhesive strength decreased, as evidenced in G3 with 11.6±1.9 MPa. <b>Conclusion:</b> The radiation power of 400 mJ, frequency of 20 Hz, and pulse duration of 50 µs improved the bond strength between lithium disilicate and dual resin cement. However, the group that obtained the lowest strength was Group 3, with a laser energy of 500 mJ/50 µs, generating highly expulsive zones in lithium disilicate.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"16 ","pages":"e54"},"PeriodicalIF":1.5,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12958272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147365574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examination of the biological effects of sunlight on the skin: a review.","authors":"Zahra Razzaghi, Alireza Ahmadzadeh","doi":"10.34172/jlms.2025.52","DOIUrl":"https://doi.org/10.34172/jlms.2025.52","url":null,"abstract":"<p><p><b>Introduction:</b> Sunlight is essential for all living beings. While certain effects of sunlight are well-established, others require further investigation. Sunlight is composed of electromagnetic spectrum radiation, which can be grouped into three main types: visible, ultraviolet (UV), and infrared (IR). UV radiation is split into three subtypes: UVA, UVB, and UVC, each of which owns unique properties and varying effects on the skin. <b>Methods:</b> In this review, the main databases, including PubMed, Scopus, and Google Scholar were investigated for studies examining the biological effects of sunlight on the skin by using suitable keywords and specific strategies from 2007 to 2024. All the studies that were not about sunlight and skin were excluded. <b>Results:</b> The influence of sunlight, particularly UV radiation can lead to a range of biological effects that may be both advantageous and detrimental. Sunlight is closely linked with common skin issues such as sunburn, skin aging, and skin cancer; therefore, the primary objective of this review is to examine the various benefits and drawbacks of sunlight exposure on human skin. The negative impact of solar radiation on the skin is especially evident with prolonged exposure, where UV radiation poses serious health risks, including squamous cell carcinoma, melanoma, and basal cell carcinoma, which are the three most common types of skin cancer. <b>Conclusion:</b> cancers mainly occur due to DNA damage induced by UV, especially UVB radiation. Furthermore, chronic exposure to UV radiation causes photoaging, which is characterized by the early onset of wrinkles, reduced elasticity, and alterations in skin pigmentation, all of which underscore the enduring effects of sunlight on the skin's texture.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"16 ","pages":"e52"},"PeriodicalIF":1.5,"publicationDate":"2025-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12958273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147365565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immediate Effect of LED Cluster on Masticatory Muscles in Children and Adolescents Diagnosed With Down Syndrome: A Pilot Study.","authors":"Rafael Zaratin Beltramin, Monise Mendes Rocha, Fabiano Politti, Alessandro Melo Deana, Raquel Agnelli Mesquita-Ferrari, Kristianne Porta Santos Fernandes, Ana Paula Taboada Sobral, Sandra Kalil Bussadori","doi":"10.34172/jlms.2025.51","DOIUrl":"https://doi.org/10.34172/jlms.2025.51","url":null,"abstract":"<p><p><b>Introduction:</b> Individuals diagnosed with Down syndrome (DS) often exhibit muscle hypotonia, particularly affecting the facial and oropharyngeal muscles involved in the mastication cycle. This condition impairs essential functions such as swallowing, speech, and chewing. Moreover, lingual hypotonia in individuals with DS can lead to problems such as snoring, obstructive sleep apnea, and bruxism. The aim of the present study was to investigate the activity of the masticatory muscles (masseter and temporalis) in individuals with DS and bruxism through electromyographic analyses before and after the application of red light-emitting diode (LED) clusters. <b>Methods:</b> Ten participants, four to 17 years of age, with diagnoses of DS and bruxism were assessed at the Integrated Health Clinic of Nove de Julho University. The masticatory muscles of the participants were submitted to electromyography (EMG) before and after the application of red LED clusters. Each cluster contained six LEDs with a wavelength of 660 nm, an optical point of 5 ± 2 mm, a dose of 2.675 J/cm², and an optical output of 2-5 mW. <b>Results:</b> The electromyographic analysis revealed changes in muscle activity after the application of the LED cluster. A reduction in asymmetry was found between the right and left masseter and temporalis muscles, and greater neuromuscular stability was found in the right masseter muscle. Although not statistically significant, these changes suggest immediate neuromodulatory effects. <b>Conclusion:</b> Although no statistically significant differences were found, the electromyographic patterns suggested improved muscle symmetry and neuromuscular stability following a single application of the LED cluster. These findings indicate the need for further investigation into the short-term effects of photobiomodulation in this population.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"16 ","pages":"e51"},"PeriodicalIF":1.5,"publicationDate":"2025-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12958268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147365573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}