Photobiomodulation Therapy in Improving Quality of Life in Kindler Syndrome: A Case Study.

Abstract

Introduction: Kindler syndrome (KS) is a rare genetic disorder characterized by skin fragility, acral blister formation, diffuse cutaneous atrophy, photosensitivity, palmoplantar hyperkeratosis, pseudosyndactyly, and alopecia. Oral manifestations include limited mouth opening, which adversely affects oral hygiene, chewing, and swallowing, significantly impacting the quality of life of affected individuals. Methods: A 26-year-old male with KS was referred for the management of reduced mouth opening, presenting with an interincisal distance of 19 mm. This was a critical concern for facilitating prosthetic rehabilitation. The patient underwent Photobiomodulation (PBM) therapy as a non-invasive treatment modality aimed at improving trismus. Results: Following PBM therapy, the patient's mouth opening improved significantly from 19 mm to 23 mm. This enhancement allowed for the initiation of prosthetic rehabilitation. Conclusion: PBM therapy is a promising treatment for managing trismus in KS by breaking down abnormal collagen deposits and reducing collagen synthesis, effectively addressing the underlying pathology. It offers significant improvements in mouth opening, which can enhance oral hygiene, nutritional intake, and overall quality of life. This non-invasive approach provides a viable option for patients with KS who require prosthetic rehabilitation.