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Comparison of Wavelength-Dependent Penetration Depth of 532 nm and 660 nm Lasers in Different Tissue Types. 532nm和660nm激光在不同组织类型中波长相关穿透深度的比较。
IF 1.5
Journal of lasers in medical sciences Pub Date : 2023-08-29 eCollection Date: 2023-01-01 DOI: 10.34172/jlms.2023.28
Ali A Aldalawi, Nursakinah Suardi, Naser Mahmoud Ahmed, Mahdi A S Al-Farawn, Mohammed Ali Dheyab, Wisam I Jebur, Faisal J Kadhim
{"title":"Comparison of Wavelength-Dependent Penetration Depth of 532 nm and 660 nm Lasers in Different Tissue Types.","authors":"Ali A Aldalawi,&nbsp;Nursakinah Suardi,&nbsp;Naser Mahmoud Ahmed,&nbsp;Mahdi A S Al-Farawn,&nbsp;Mohammed Ali Dheyab,&nbsp;Wisam I Jebur,&nbsp;Faisal J Kadhim","doi":"10.34172/jlms.2023.28","DOIUrl":"https://doi.org/10.34172/jlms.2023.28","url":null,"abstract":"<p><p><b>Introduction:</b> The depth of laser light penetration into tissue is a critical factor in determining the effectiveness of photodynamic therapy (PDT). However, the optimal laser light penetration depth necessary for achieving maximum therapeutic outcomes in PDT remains unclear. This study aimed to assess the effectiveness of laser light penetration depth at two specific wavelengths, 532 nm and 660 mm. <b>Methods:</b> Chicken and beef of different thicknesses (1, 3, 5, 10, and 20 mm±0.2 mm) were used as in vitro tissue models. The samples were subjected to irradiation by a low-level laser diode of 532 and 660 nm in continuous mode for 10 minutes. with power densities of 167 and 142 J/cm<sup>2</sup>, respectively. Laser light transmission through the tissue was measured using a power meter. <b>Results:</b> For beef samples, the 660 nm wavelength achieved a maximum transmission intensity of 30.7% at 1 cm thickness, while the 532 nm laser had a transmission intensity of 6.5%. Similarly, in chicken breast samples, the maximum transmission occurred at 1 cm thickness with 68.1% for the 660 nm wavelength and 18.2% for the 532 nm laser. <b>Conclusion:</b> Results consistently demonstrated a significant correlation (<i>P</i><0.05) between tissue thickness and laser light penetration. Thicker tissues exhibited faster declines in light transmission intensity compared to thinner tissues within 10 minutes. These findings highlight the importance of further research to enhance light delivery in thicker tissues and improve the efficacy of PDT in various medical conditions.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517573/pdf/jlms-14-e28.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41114982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combination of Fractional Er:YAG Laser, Pulsed Dye Laser, and Intralesional Triamcinolone With 5-Fluorouracil for Keloid Treatment. 部分Er:YAG激光、脉冲染料激光和病灶内曲安奈德联合5-氟尿嘧啶治疗瘢痕疙瘩。
IF 1.5
Journal of lasers in medical sciences Pub Date : 2023-08-29 eCollection Date: 2023-01-01 DOI: 10.34172/jlms.2023.30
Bonnie Yudistha Anggawirya, Putri Hendria Wardhani, Diah Mira Indramaya, Muhammad Yulianto Listiawan
{"title":"Combination of Fractional Er:YAG Laser, Pulsed Dye Laser, and Intralesional Triamcinolone With 5-Fluorouracil for Keloid Treatment.","authors":"Bonnie Yudistha Anggawirya,&nbsp;Putri Hendria Wardhani,&nbsp;Diah Mira Indramaya,&nbsp;Muhammad Yulianto Listiawan","doi":"10.34172/jlms.2023.30","DOIUrl":"10.34172/jlms.2023.30","url":null,"abstract":"<p><p><b>Introduction:</b> Benign fibroproliferative scars that are larger than the initial lesion are called keloids. Keloids treatment in clinical practice is still difficult. Although there are various therapy choices, none is embraced by everyone or is relapse-free. Various treatment modalities such as intralesional corticosteroid injection with 5-fluorouracil (5-FU), fractional Er:YAG laser, pulsed dye laser (PDL), and others can be used either as monotherapies or combined therapies. Therefore, efforts should be made to select the treatment that will provide the best results. <b>Case Presentation:</b> A 6-year-old boy with keloids on the lower lips extending to the chin was successfully treated with a 2940-nm fractional Er:YAG laser alternated with a 595-nm long-PDL followed by the combined intralesional injection of corticosteroid and 5-FU. The patient was followed up for 1 year with no lesion recurrence. <b>Conclusion:</b> Our case supports a combined therapy to successfully treat a patient with a keloid on the chin. Therapy using a combination of these four modalities seems safe and effective and may have a synergistic effect with minimal downtime.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517570/pdf/jlms-14-e30.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41135782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Good Craftsperson Knows Their Tools: Understanding of Laser and Ureter Mechanics in Training Urologists. 一个好的工匠知道他们的工具:在培训泌尿科医生时理解激光和输尿管力学。
IF 1.5
Journal of lasers in medical sciences Pub Date : 2023-08-29 eCollection Date: 2023-01-01 DOI: 10.34172/jlms.2023.29
Sorcha O'Meara, Stefanie Croghan, Fergal J O'Brien, Niall F Davis
{"title":"A Good Craftsperson Knows Their Tools: Understanding of Laser and Ureter Mechanics in Training Urologists.","authors":"Sorcha O'Meara,&nbsp;Stefanie Croghan,&nbsp;Fergal J O'Brien,&nbsp;Niall F Davis","doi":"10.34172/jlms.2023.29","DOIUrl":"https://doi.org/10.34172/jlms.2023.29","url":null,"abstract":"<p><p><b>Introduction:</b> Recent decades have seen a move to minimally invasive techniques to manage urolithiasis. Trainees are expected to develop competency in common endourology procedures. Knowledge of ureter mechanics and the theory behind new technologies is important to ensure safe and efficient techniques. We aim to evaluate the exposure to endourology, self-reported competency in common techniques and knowledge of basic ureter biomechanics and technology in training urologists. <b>Methods:</b> An online survey was circulated to all training urologists in the Republic of Ireland. Questions focused on self-reported competency, clinical knowledge, ureter mechanical properties and laser technology. <b>Results:</b> Thirty responses were received with a range of 1-8 years of urology experience (mean=4 years). The respondents reported high levels of exposure to endourology with the majority reporting competency in flexible ureterorenoscopy (FURS) (n=18, 60%) and semi-rigid ureteroscopy (URS) (n=21, 70%). The respondents demonstrated good clinical knowledge but variable knowledge of laser settings, laser thermodynamics and ureter mechanics. Half of the respondents (n=15, 50%) correctly described fragmentation laser settings, with 10 trainees (n=33%) accurately identifying both factors that increase ureteral access sheath (UAS) insertion force. Most of the respondents (n=20, 67%) described the proximal ureter as the site with the greatest compliance, while the site of the greatest force during ureteroscope insertion was correctly identified by 17% (n=5). <b>Conclusion:</b> To our knowledge, this represents the first study evaluating urologist understanding of laser technology and the mechanical properties of the human ureter. Despite trainees reporting high levels of experience in endourology, there is a variable understanding of the principles of laser technology and ureter mechanics. Further research and education are needed with a focus on laser safety, suitable laser settings and the safe limit of insertion forces.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517579/pdf/jlms-14-e29.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41122320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long and Short-terms Effects of Ablative Fractional Laser Therapy on Human Skin: A Network Analysis. 消融部分激光治疗对人类皮肤的长期和短期影响:网络分析。
IF 1.5
Journal of lasers in medical sciences Pub Date : 2023-08-27 eCollection Date: 2023-01-01 DOI: 10.34172/jlms.2023.27
Zahra Razzaghi, Babak Arjmand, Mostafa Rezaei Tavirani, Maryam Hamzeloo-Moghadam, Mohammad Rostami Nejad, Reza Mohamoud Robati
{"title":"Long and Short-terms Effects of Ablative Fractional Laser Therapy on Human Skin: A Network Analysis.","authors":"Zahra Razzaghi,&nbsp;Babak Arjmand,&nbsp;Mostafa Rezaei Tavirani,&nbsp;Maryam Hamzeloo-Moghadam,&nbsp;Mohammad Rostami Nejad,&nbsp;Reza Mohamoud Robati","doi":"10.34172/jlms.2023.27","DOIUrl":"https://doi.org/10.34172/jlms.2023.27","url":null,"abstract":"<p><p><b>Introduction:</b> Time-dependent effects of laser radiation have been investigated by researchers. An understanding of the molecular mechanism of the time course effect of the laser needs molecular assessment and function evaluation of the related genes. In the present study, the importance of repetition of treatment after 4 weeks and gene expression alteration after 7 days of laser radiation versus one day on the human skin was evaluated via protein-protein interaction (PPI) network analysis and gene ontology enrichment. <b>Methods:</b> The differentially expressed genes (DEGs) were extracted from Gene Expression Omnibus (GEO) and assessed via PPI network analysis. The critical DEGs were enriched via gene ontology. The related biological processes and biochemical pathways were retrieved from \"GO-Biological process\" and \"Kyoto Encyclopedia of Genes and Genomes\" (KEGG) respectively. <b>Results:</b> The repetition of laser therapy after 4 weeks of the first treatment did not have a significant effect on treatment efficacy. Sixty-three significant DEGs and six classes of biological terms discriminated the samples seven days after the treatment from individuals one day after the treatment. The studied DEGs were organized into two clusters with certain functions. <b>Conclusion:</b> Based on the findings after laser therapy, several days are required to complete the critical processes such as DNA biosynthesis and skin cornification.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517572/pdf/jlms-14-e27.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41103169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment Modelling of a 3D Tumour in Brain by Laser-Induced Interstitial Thermotherapy. 激光诱导间质热疗对脑三维肿瘤的治疗建模。
IF 1.5
Journal of lasers in medical sciences Pub Date : 2023-08-22 eCollection Date: 2023-01-01 DOI: 10.34172/jlms.2023.26
Sadegh Amini, Hossein Ahmadikia
{"title":"Treatment Modelling of a 3D Tumour in Brain by Laser-Induced Interstitial Thermotherapy.","authors":"Sadegh Amini,&nbsp;Hossein Ahmadikia","doi":"10.34172/jlms.2023.26","DOIUrl":"https://doi.org/10.34172/jlms.2023.26","url":null,"abstract":"<p><p><b>Introduction:</b> There are some ways to examine heat transfer in tumor tissue, which is an important issue in bioengineering. One of these ways uses the bioheat equation, proposed by Pennes, in a continuous medium. Another one uses a porous medium to model heat transfer in living tissues. The objective of this paper was to study an approach to modelling the temperature distribution and tumour ablation in brain tissue and compare results to Pennes' approach. <b>Methods:</b> This approach presents and uses a porous medium as the tissue instead of a continuous medium. In addition, the two approaches (simulation in continuous and porous medium) are compared in terms of temperature simulation and amount of cell ablation. The density, heat conduction factor, and blood perfusion rate are considered functions of temperature. <b>Results:</b> In these approaches, after an 85-second treatment, the temperature increases to about 90°C. The temperature increase of the porous medium is relatively the same as that of the continuous medium and for this reason, the amount of cancerous cells that are ablated in a porous medium is approximately the same as that in a continuous medium. The volume of cell ablation is about 6500 mm<sup>3</sup> for two ideas. In addition, the degree of damage, computed from the Arrhenius integral method, and the ablated volume of the tumour endorse equality at the end of treatment. According to the results, similar to the continuous approach, the porous approach predicts the temperature and amount of volume of damaged cells. <b>Conclusion:</b> Therefore, it is possible to use the porous approach instead of the Pennes approach for tumour treatment.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517584/pdf/jlms-14-e26.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41128103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Introducing Critical Genes in Response to Photodynamic Therapy: A Network Analysis. 光动力疗法中关键基因的引入:网络分析。
IF 1.5
Journal of lasers in medical sciences Pub Date : 2023-08-10 eCollection Date: 2023-01-01 DOI: 10.34172/jlms.2023.25
Vahid Mansouri, Babak Arjmand, Maryam Hamzeloo-Moghadam, Mostafa Rezaei Tavirani, Zahra Razzaghi, Alireza Ahmadzadeh, Mohammad Rostami Nejad, Reza Mohamoud Robati
{"title":"Introducing Critical Genes in Response to Photodynamic Therapy: A Network Analysis.","authors":"Vahid Mansouri,&nbsp;Babak Arjmand,&nbsp;Maryam Hamzeloo-Moghadam,&nbsp;Mostafa Rezaei Tavirani,&nbsp;Zahra Razzaghi,&nbsp;Alireza Ahmadzadeh,&nbsp;Mohammad Rostami Nejad,&nbsp;Reza Mohamoud Robati","doi":"10.34172/jlms.2023.25","DOIUrl":"https://doi.org/10.34172/jlms.2023.25","url":null,"abstract":"<p><p><b>Introduction:</b> Photodynamic therapy (PDT) is applied as an efficient method for preventing the progress of cancers. Light and a photosensitive compound which is known as photosensitizer (PS) are the main parts of PDT. In the present study, molecular events after using PDT in the presence of a super lethal dose of a PS were assessed via protein-protein interaction (PPI) analysis. <b>Methods:</b> Data were extracted from Gene Expression Omnibus (GEO). The gene expression profiles of the treated human Sk-Cha1 cells via PDT were compared with the control cells. Expressed change analysis and PPI network analysis were administrated via Cytoscape software v 3.7.2 to find the critical differentially expressed genes (DEGs). Regulatory relationships between the central DEGs were evaluated and the highlighted genes were identified. <b>Results:</b> The significant amounts of gene expression values were grouped and a few DEGs characterized by tremendously expressed values were identified. EGFR, CANX, HSPA5, MYC, JUN, ITGB1, APP, and CDH1 were highlighted as hub-bottleneck DEGs. EGFR, CDH1, and JUN appeared as a set of SEGs, which play a crucial role in response to PDT in the treated Sk-Cha1 cells. <b>Conclusion:</b> In conclusion, regulatory relationships between EGFR, CDH1, and JUN, which have an effect on the regulation of cellular survival, differentiation, and proliferation, were highlighted in the present investigation.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517577/pdf/jlms-14-e25.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41125239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Photobiomodulation on Temporomandibular Pain and Functions in Patients With Temporomandibular Disorders: An Updated Systematic Review of the Current Randomized Controlled Trials. 光生物调节对颞下颌疾病患者颞下颌疼痛和功能的影响:当前随机对照试验的最新系统综述。
IF 1.5
Journal of lasers in medical sciences Pub Date : 2023-08-05 eCollection Date: 2023-01-01 DOI: 10.34172/jlms.2023.24
Nima Farshidfar, Golnoush Farzinnia, Nazafarin Samiraninezhad, Sahar Assar, Parsa Firoozi, Fahimeh Rezazadeh, Neda Hakimiha
{"title":"The Effect of Photobiomodulation on Temporomandibular Pain and Functions in Patients With Temporomandibular Disorders: An Updated Systematic Review of the Current Randomized Controlled Trials.","authors":"Nima Farshidfar,&nbsp;Golnoush Farzinnia,&nbsp;Nazafarin Samiraninezhad,&nbsp;Sahar Assar,&nbsp;Parsa Firoozi,&nbsp;Fahimeh Rezazadeh,&nbsp;Neda Hakimiha","doi":"10.34172/jlms.2023.24","DOIUrl":"https://doi.org/10.34172/jlms.2023.24","url":null,"abstract":"<p><p><b>Introduction:</b> Temporomandibular disorders (TMDs) are the most prevalent non-dental origin orofacial pain conditions affecting the temporomandibular joints (TMJs) and/or orofacial muscles. Photobiomodulation therapy (PBMT) is a conservative way to improve function and reduce symptoms in TMD patients. This systematic review was conducted to update evidence about the effects of PBMT on pain intensity, TMJ movements, electromyography (EMG) activity, pressure pain threshold (PPT), and TMJ sound in patients with TMDs. <b>Methods:</b> A systematic literature search was conducted in Web of Science, PubMed/Medline, and Scopus databases using appropriate keywords and specific strategies from January 2000 to September 2022. Data extraction was done based on the inclusion/exclusion criteria. <b>Results:</b> A total of 40 studies were included. All included studies except one provided information on pain intensity; 27 studies showed a reduction in pain intensity in PBMT groups compared to control groups. Seven out of 15 studies, which reported maximum mouth opening (MMO), showed a greater MMO in PBMT groups than in placebo groups. In addition, the figures for passive maximum mouth opening (PMMO) and active maximum mouth opening (AMMO) in all the studies reporting PMMO and AMMO were higher in PBMT groups. In eight out of ten studies, lateral movement (LM) was greater in PBMT groups. Moreover, in three studies out of four, protrusive movement (PM) was reported to be greater in the PBMT group. Four out of nine studies showed a greater PPT in the PBMT group. Reduced TMJ sounds in the PBMT group were reported in two out of five studies. In addition, in most studies, no difference in EMG activity was detected between the two groups. <b>Conclusion:</b> This updated systematic review showed the promising effects of PBMT on the alleviation of pain and improvement in MMO. Using the infrared diode laser with a wavelength ranging between 780-980 nm, an energy density of<100 J/ cm<sup>2</sup>, and an output power of≤500 mW for at least six sessions of treatment seems to be a promising option for treating mentioned TMDs signs and symptoms based on the previously reported findings.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517581/pdf/jlms-14-e24.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41103170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Photobiomodulation Therapy With an 810-nm Diode Laser on Pain Perception Associated With Dental Injections in Children: A Double-Blind Randomized Controlled Clinical Trial. 使用 810 纳米二极管激光的光生物调节疗法对儿童牙科注射疼痛感的影响:双盲随机对照临床试验》。
IF 1.4
Journal of lasers in medical sciences Pub Date : 2023-06-19 eCollection Date: 2023-01-01 DOI: 10.34172/jlms.2023.19
Bahman Seraj, Anise Bavaghar, Neda Hakimiha, Zahra Hosseini, Mohammad Javad Kharazifard, Sara Ghadimi
{"title":"Effect of Photobiomodulation Therapy With an 810-nm Diode Laser on Pain Perception Associated With Dental Injections in Children: A Double-Blind Randomized Controlled Clinical Trial.","authors":"Bahman Seraj, Anise Bavaghar, Neda Hakimiha, Zahra Hosseini, Mohammad Javad Kharazifard, Sara Ghadimi","doi":"10.34172/jlms.2023.19","DOIUrl":"10.34172/jlms.2023.19","url":null,"abstract":"<p><p><b>Introduction:</b> This study investigated the photobiomodulation effect of an 810-nm diode laser in adjunction with topical anesthesia on pain perception during infiltration anesthesia of primary maxillary molars in children. <b>Methods:</b> This double-blind randomized controlled clinical trial was conducted on 64 children (aged 5-9 years) requiring extraction or stainless steel crown for their primary maxillary molars. The patients were randomly allocated into two groups (n=32) of laser and control. In the laser group, the injection site (buccal and palatal mucosa) was irradiated with an 810-nm laser (200 mW, 5.2 J/cm<sup>2</sup>) after 20% benzocaine topical anesthetic application, while the control group received a placebo laser following topical anesthesia. The pain intensity experienced by children during needle insertion into the buccal and palatal mucosa was determined using a visual analog scale (VAS) and modified behavioral pain scale (MBPS). <b>Results:</b> According to the results of the VAS and MBPS, no significant difference was detected in pain scores between the laser and control groups neither in the buccal nor in the palatal mucosa (<i>P</i>>0.05). <b>Conclusion:</b> Photobiomodulation therapy with an 810-nm laser with the current setting adjunct to topical anesthesia did not promote significant additional effects on the pain intensity.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10423958/pdf/jlms-14-e19.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10388263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Keloid Treatment Using Plasma Exeresis: A Pilot Trial Study. 使用血浆运动治疗瘢痕疙瘩:一项试点试验研究。
IF 1.5
Journal of lasers in medical sciences Pub Date : 2023-01-01 DOI: 10.34172/jlms.2023.07
Shohreh Delavar, Setareh Tehrani, Hournaz Hassanzadeh, Sepideh Tehrani
{"title":"Keloid Treatment Using Plasma Exeresis: A Pilot Trial Study.","authors":"Shohreh Delavar,&nbsp;Setareh Tehrani,&nbsp;Hournaz Hassanzadeh,&nbsp;Sepideh Tehrani","doi":"10.34172/jlms.2023.07","DOIUrl":"https://doi.org/10.34172/jlms.2023.07","url":null,"abstract":"<p><p><b>Introduction:</b> Keloid scars and hypertrophic scars are more commonly seen after surgeries, suture placements, or other skin damages. Scars can be treated using a variety of methods, including topical compounds, surgery, and lasers. The aim of this study is to evaluate the effects of plasma exeresis on the treatment of keloid scars. <b>Methods:</b> This experimental study was conducted on patients with keloid scars, defined as a treatment-resistant subtype of scars with extension beyond the primary skin defect and cauliflower appearance, in different parts of the body. The patients were treated with 2-to-3-session plasma exeresis. Scars were examined based on the Vancouver scar scale (VSS) before and 5 months after the treatment. <b>Results:</b> A total number of 24 scars were enrolled in this study. The number of patients was 16. There was a decrease in the mean thickness of keloids from 2.20 to 0.54 (<i>P</i>=0.000). The mean pigmentation and pliability scores decreased from 1.54 and 2.16 to 0.375 and 0.541, respectively (<i>P</i>=0.001, 000). There was a significant reduction in the keloid scar vascularity score from 1.666 to 0.541 (<i>P</i>=0.000). There was a decrease from 0.708 to 0.00 (<i>P</i>=0.004) in the mean itchiness score. After the intervention, the mean pain score was 0.000, compared to 0.7500 before the intervention (<i>P</i>=0.003). There was a decrease in the total score from 8.958 to 2.000 (<i>P</i>=0.000). <b>Conclusion:</b> The plasma exeresis procedure is effective in destroying small keloid scars. Furthermore, results in less itching and pain, as well as no significant complications or recurrences.</p>","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114038/pdf/jlms-14-e7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9380340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Critically Ill Patients With COVID-19: Are Phototherapies Advantageous for Managing Orofacial Lesions? Our Experience With Brazilian Hospitals. COVID-19危重患者:光疗法对治疗口面部病变有利吗?我们在巴西医院的经验。
IF 1.5
Journal of lasers in medical sciences Pub Date : 2023-01-01 DOI: 10.34172/jlms.2023.05
Luana Campos, Inessa Solek Teixeira, Marcia Christina Camargo Hernandes Ramires, Regina Maria Raffaele, Luiz Felipe Palma
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引用次数: 2
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