Journal of lasers in medical sciences最新文献_第9页

Use of Phototherapy and Er-YAG Laser in the Management of Mandible Osteoradionecrosis: A Case Report. 使用光疗和 Er-YAG 激光治疗下颌骨骨坏死：病例报告。

IF 1.5

Journal of lasers in medical sciences Pub Date : 2023-11-26 eCollection Date: 2023-01-01 DOI: 10.34172/jlms.2023.58

Larissa Couto de Freitas, Elenice Lika Kawamoto, Ana Maria Aparecida Souza, Paulo Yataro Kawakami, Alyne Simões Gonçalves, Luciane Hiramatsu Azevedo

{"title":"Use of Phototherapy and Er-YAG Laser in the Management of Mandible Osteoradionecrosis: A Case Report.","authors":"Larissa Couto de Freitas, Elenice Lika Kawamoto, Ana Maria Aparecida Souza, Paulo Yataro Kawakami, Alyne Simões Gonçalves, Luciane Hiramatsu Azevedo","doi":"10.34172/jlms.2023.58","DOIUrl":"https://doi.org/10.34172/jlms.2023.58","url":null,"abstract":"Introduction: Osteoradionecrosis (ORN) is a secondary complication from radiotherapy, which is difficult to manage and significantly reduces the life quality of the affected patients. Case Report: A 59-year-old female patient, diagnosed with infiltration by squamous cell carcinoma in the left cervical region, underwent adjuvant cervical-facial radiotherapy with a total dose of 66.6 Gy of radiation. Eight years after the diagnosis, the patient underwent multiple extractions and, subsequently, the installation of osseointegrated implants, evolving to extensive intraoral bone exposure associated with oral cutaneous fistula. The patient was initially exposed to photobiomodulation therapy (PBMT), with a low-power laser at wavelengths of 660 nm and 808 nm, and thereafter to antimicrobial photodynamic therapy (aPDT). After an improvement in the clinical condition and resolution of the oral cutaneous fistula, a surgical procedure with the Er: YAG laser was performed to remove the remaining necrotic bone. Once the ORN condition was completely treated, the patient's oral rehabilitation was implemented by the installation of an upper mucous-supported total prosthesis and a lower implant-supported prosthesis. Conclusion: The patient is in a clinical follow-up and has no signs of bone necrosis recurrence, suggesting that low and high-power laser treatment can be an effective therapeutic alternative to resolve this condition.","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"14 ","pages":"e58"},"PeriodicalIF":1.5,"publicationDate":"2023-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10746881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139032408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the Effect of NovaMin and Er,Cr:YSGG Laser on Remineralization of Erosive Lesions of Primary Enamel Teeth: An In Vitro Study. 评估 NovaMin 和 Er,Cr:YSGG 激光对原生釉质牙齿腐蚀性病变再矿化的影响：体外研究。

IF 1.5

Journal of lasers in medical sciences Pub Date : 2023-11-13 eCollection Date: 2023-01-01 DOI: 10.34172/jlms.2023.56

Yoones Sadabadi, Majid Mehran, Mohammad Bagher Rezvani, Mohammad Asnaashari, Roza Haghgoo

{"title":"Evaluation of the Effect of NovaMin and Er,Cr:YSGG Laser on Remineralization of Erosive Lesions of Primary Enamel Teeth: An In Vitro Study.","authors":"Yoones Sadabadi, Majid Mehran, Mohammad Bagher Rezvani, Mohammad Asnaashari, Roza Haghgoo","doi":"10.34172/jlms.2023.56","DOIUrl":"https://doi.org/10.34172/jlms.2023.56","url":null,"abstract":"Introduction: The purpose of this in vitro study is to ascertain how NovaMin and Er,Cr:YSGG laser radiation affect the remineralization of primary tooth enamel lesions. Methods: 40 main teeth served as the study's sample size. These teeth were allocated into five groups at random. The first group served as a negative control (artificial saliva); the second group served as a positive control (APF gel 1.23%); the third group NovaMin, the fourth group Er,Cr:YSGG laser, the fifth group Er,Cr:YSGG laser and finally, the application of NovaMin. For the purpose of measuring microhardness, all samples were submitted to the dental materials laboratory three times. Results: The collected data were compared using the SPSS 28 program between the baseline measurement, after demineralization, and after remineralization. The data were analyzed using ANCOVA and Bonferroni tests. All groups demonstrated a considerable increase in microhardness as compared to the negative control group (P<0.05). With the exception of the third and fourth groups, there was no discernible difference in the rise in microhardness between the other groups. The third and fourth groups were compared, and the results revealed that NovaMin had a greater impact than laser therapy alone (P=0.023). Scanning electron microscopy (SEM) analysis backed up the findings. Conclusion: In comparison to using the Er,Cr:YSGG laser alone, using NovaMin alone can speed up the remineralization of erosion lesions on the surface of primary teeth.","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"14 ","pages":"e56"},"PeriodicalIF":1.5,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10746883/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139032407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Brief Review of Low-Level Light Therapy in Depression Disorder. 低强度光治疗抑郁症的研究进展

IF 1.5

Journal of lasers in medical sciences Pub Date : 2023-11-11 eCollection Date: 2023-01-01 DOI: 10.34172/jlms.2023.55

Afshan Shirkavand, Maryam Akhavan Tavakoli, Zeinab Ebrahimpour

{"title":"A Brief Review of Low-Level Light Therapy in Depression Disorder.","authors":"Afshan Shirkavand, Maryam Akhavan Tavakoli, Zeinab Ebrahimpour","doi":"10.34172/jlms.2023.55","DOIUrl":"https://doi.org/10.34172/jlms.2023.55","url":null,"abstract":"Introduction: Low-level laser therapy (LLLT), also called Photobiomodulation, has gained widespread acceptance as a mainstream modality, particularly in the form of photobiostimulation (PBM). Here in our review, we aim to present the application of LLLT to help with depression, explore potential action mechanisms and pathways, discuss existing limitations, and address the challenges associated with its clinical implementation. Methods: In biological systems, the visible light with a wavelength range of 400-700 nm activates photoreceptors involved in vision and circadian rhythm regulation. The near-infrared (NIR) light with a wavelength range of 800-1100 nm exhibits superior tissue penetration capabilities compared to the visible light, which enables the non-invasive application of LLLT to various tissues. Results: By enhancing adenosine triphosphate (ATP) production using the respiratory chain, LLLT is able to enhance blood flow, reduce inflammation, support repair and healing, and enhance stem cell growth and proliferation. Preclinical studies using animal models have shown promising neuroprotective effects of the LLLT method on central nervous system (CNS) diseases, suggesting potential improvements in brain function for patients suffering from Alzheimer's disease. In addition, it helps Parkinson's patients with their movement problems and ameliorates mental disorders in individuals with depression. Conclusion: patients' quality of life can be significantly enhanced. A comprehensive understanding of the protective effects and underlying mechanisms of LLLT will facilitate its therapeutic application in the future.","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"14 ","pages":"e55"},"PeriodicalIF":1.5,"publicationDate":"2023-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658118/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138460377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Non-thermal CO2 Laser Therapy (NTCLT): A Novel Photobiomodulative Approach for Immediate Pain Relief of Patchy Oral Mucositis Due to Chemotherapy of Solid Tumors 非热CO2激光治疗(NTCLT):一种新的光生物调节方法，可立即缓解实体肿瘤化疗引起的斑片状口腔黏膜炎的疼痛

Journal of lasers in medical sciences Pub Date : 2023-11-08 DOI: 10.34172/jlms.2023.54

Nasrin Zand, Safa Najafi, Mohsen Fateh, Jila Sadighi, Parvin Mansouri, Mohammad Farhadi, Leila Ataie-Fashtami, Alireza Nikoofar, Hoda Mahdavi, Afshan Shirkavand

{"title":"Non-thermal CO2 Laser Therapy (NTCLT): A Novel Photobiomodulative Approach for Immediate Pain Relief of Patchy Oral Mucositis Due to Chemotherapy of Solid Tumors","authors":"Nasrin Zand, Safa Najafi, Mohsen Fateh, Jila Sadighi, Parvin Mansouri, Mohammad Farhadi, Leila Ataie-Fashtami, Alireza Nikoofar, Hoda Mahdavi, Afshan Shirkavand","doi":"10.34172/jlms.2023.54","DOIUrl":"https://doi.org/10.34172/jlms.2023.54","url":null,"abstract":"Introduction: Chemotherapy-induced oral mucositis (COM) is a prominent complication of chemotherapy (CT). Non-thermal CO2 laser therapy (NTCLT) has been demonstrated as an innovative and safe photobiomodulative approach in some kinds of painful oral lesions. The purpose of this study was to evaluate the palliative effects of one session of NTCLT on COM lesions. Methods: Patients with painful COM (WHO grade:≥2) were included in this before-after clinical trial based on the eligibility criteria. The oral lesions were irradiated with a CO2 laser (power: 1 W, scanning the lesions with the rapid circular motion of the defocused handpiece) through a thick layer (3-4 mm) of a transparent gel containing a high-water content. The severity of pain in the lesions was self-assessed using a 0-to-10 visual analogue scale (VAS) for 7 consecutive days. The evaluating physician visited the patients on the 3rd and 7th days in search of any kind of complications. Results: Seventeen adult patients with 35 patches of OM due to chemotherapy of solid tumors completed the trial. Immediately after NTCLT, the mean for non-contact VAS pain scores of the lesions significantly declined from 4.91±2.356 to 0.29±0.622 (P<0.001) and the mean for contact VAS pain scores from 7.77±1.57 to 1.31±1.18 (P<0.001). The mean VAS pain scores of the lesions showed statistically significant differences between the follow-up periods compared to the baseline (P<0.001). The process was completely pain-free and required no anesthesia. After NTCLT, no kind of thermal adverse effects such as irritation, destruction, aggravation and even erythema were observed. Conclusion: Based on the results of this before-after clinical trial, NTCLT has the potential to be considered as a non-invasive and safe palliative option for the pain management of patchy OM due to chemotherapy of solid tumors.","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"60 12","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135431818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of Photosensitizer Concentration Effects on the Efficacy of Photodynamic Therapy 光敏剂浓度对光动力治疗效果影响的评价

Journal of lasers in medical sciences Pub Date : 2023-11-08 DOI: 10.34172/jlms.2023.53

Reza Vafaee, Babak Arjmand, Maryam Hamzeloo-Moghadam, Mostafa Rezaei Tavirani, Zahra Razzaghi, Reza M Robati, Mitra Rezaei, Fatemeh Montazer

{"title":"Assessment of Photosensitizer Concentration Effects on the Efficacy of Photodynamic Therapy","authors":"Reza Vafaee, Babak Arjmand, Maryam Hamzeloo-Moghadam, Mostafa Rezaei Tavirani, Zahra Razzaghi, Reza M Robati, Mitra Rezaei, Fatemeh Montazer","doi":"10.34172/jlms.2023.53","DOIUrl":"https://doi.org/10.34172/jlms.2023.53","url":null,"abstract":"Introduction: Photodynamic therapy (PDT) is an attractive approach in medicine. Due to its noninvasive nature and low side effects, PDT has been developed quickly. In the present study, the gene expression profiles of the human cell line that was treated via PDT in the sub-lethal concentration (LC50) and super-lethal concentration (LC90) of a photosensitizer (PS) from Gene Expression Omnibus (GEO) were extracted and the common differentially expressed genes (DEGs) were investigated. Methods: The gene expression profiles of the treated cells were compared with a control, and the common DEGs were determined. The common DEGs were assessed via protein-protein interaction (PPI) network analysis, and gene ontology enrichment was evaluated. The related biological terms for the common genes were identified. Results: Ninety-four common DEGs were selected to be analyzed. It appeared that the activation and increment of gene expression were prominent processes. Jun, Dusp1, Atf4, and Atf3 as four critical genes were highlighted. \"Chromosomal and microsatellite instability in colorectal cancer\" was identified as the main class of biological terms related to the assessed DEGs. Conclusion: The major molecular events which happened in both analyses indicated that PDT, independent from the concentration of PS, induced gross molecular changes such as the upregulation of Jun and Dusp1.","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"60 11","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135431819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In Vitro Comparative Evaluation of the Efficacy of Antimicrobial Photodynamic Therapy, Chlorhexidine, Sodium Fluoride, and Hydrogen Peroxide for Acrylic Resin Disinfection 抗菌光动力疗法、氯己定、氟化钠和过氧化氢对丙烯酸树脂消毒效果的体外比较评价

Journal of lasers in medical sciences Pub Date : 2023-11-04 DOI: 10.34172/jlms.2023.52

Farhad Sobouti, Sepideh Dadgar, Aysan Salehi, Nika Rezaei Kalantari, Mehdi Aryana, Hamid Reza Goli, Mohadeseh Heidari

{"title":"In Vitro Comparative Evaluation of the Efficacy of Antimicrobial Photodynamic Therapy, Chlorhexidine, Sodium Fluoride, and Hydrogen Peroxide for Acrylic Resin Disinfection","authors":"Farhad Sobouti, Sepideh Dadgar, Aysan Salehi, Nika Rezaei Kalantari, Mehdi Aryana, Hamid Reza Goli, Mohadeseh Heidari","doi":"10.34172/jlms.2023.52","DOIUrl":"https://doi.org/10.34172/jlms.2023.52","url":null,"abstract":"Introduction: Plaque accumulation on the surface of removable orthodontic appliances could lead to dental caries, periodontitis, and fungal infections. This study evaluated the effectiveness of antimicrobial photodynamic therapy (aPDT), chlorhexidine (CHX), sodium fluoride (NaF), and hydrogen peroxide (H2 O2 ) for the disinfection of acrylic resin. Methods: In this in vitro experimental study, 100 acrylic resin specimens were randomly divided into five groups (n=20 each): Enterococcus faecalis, Streptococcus mutans, Streptococcus salivarius, Streptococcus sanguinis, and Lactobacillus acidophilus. Each group was immersed separately in 5 mL of microbial suspension. They were then incubated until biofilm formation on their surface. Of each microorganism, one biofilm sample in phosphate-buffered saline was considered as negative control, and other biofilm samples (n=80) were subjected to aPDT with curcumin, 0.12% CHX (positive control), 1% H2 O2 , and 0.2% NaF. Finally, the number of colonies was counted. Data were analyzed by the Kruskal-Wallis and Mann-Whitney tests, two-way ANOVA, and Bonferroni adjustment at a significance level of 0.05. Results: The interaction effect of the treatment modality and type of microorganism was significant on the microbial count (effect size: 0.91, P<0.05). Maximum bacterial proliferation was noted in the following combinations: NaF/E. faecalis, H2 O2 /E. faecalis, and H2 O2 /S. salivarius. Microorganisms had no or insignificant growth and proliferation in the aPDT and CHX groups. Conclusion: The results supported the optimal antimicrobial efficacy of PDT which was comparable to that of CHX. aPDT showed superior antimicrobial efficacy to NaF and H2 O2 for the disinfection of acrylic resin.","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"260 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135775731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the Efficacy of Fractional Carbon Dioxide Laser as an Add-on Combination to Conventional Therapies for Treatment-Resistant Vitiligo (A Review Article) 部分二氧化碳激光辅助治疗难治性白癜风的疗效探讨(综述)

Journal of lasers in medical sciences Pub Date : 2023-11-01 DOI: 10.34172/jlms.2023.51

Parvin Mansouri, Mohammadreza Rahbar, Mohammad Ali Nilforoushzadeh, Mohsen Shati

{"title":"Exploring the Efficacy of Fractional Carbon Dioxide Laser as an Add-on Combination to Conventional Therapies for Treatment-Resistant Vitiligo (A Review Article)","authors":"Parvin Mansouri, Mohammadreza Rahbar, Mohammad Ali Nilforoushzadeh, Mohsen Shati","doi":"10.34172/jlms.2023.51","DOIUrl":"https://doi.org/10.34172/jlms.2023.51","url":null,"abstract":"Introduction: Vitiligo, a dermatological disorder that leads to depigmented skin patches, presents a significant challenge, particularly in resistant areas such as acral regions. Fractional CO2 laser therapy holds promise as an adjunct to conventional treatment, enhancing repigmentation. This review comprehensively explores its efficacy and safety in resistant-to-treatment vitiligo. Methods: We conducted extensive database searches in PubMed, Embase, and Cochrane, focusing on English-language literature published between 2012 and 2023. We included comparative studies that met the following criteria: (1) Participants had non-segmental vitiligo, with resistant-to-treatment localization engagement; (2) The treatment involved the use of fractional CO2 laser in combination with conventional therapies; and (3) Outcomes were assessed based on the repigmentation ratio or significant difference. We excluded studies from which data from published results could not be extracted. Results: After extensive screening of 52 articles, we finally selected five studies. The results showed that fractional CO2 laser therapy, when combined with other treatments, often shows promise in vitiligo treatment in refractory cases. Although individual responses varied, overall efficacy and safety were promising, with minimal adverse effects and no severe complications. Conclusion: The fractional CO2 laser, when used in conjunction with conventional therapies, emerges as a promising option for treating refractory vitiligo. Large-scale randomized trials and a deeper understanding of the underlying mechanisms are vital for future progress in optimizing treatment protocols, case selection, and safety.","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"35 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135564751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unveiling Therapeutic Potential: A Systematic Review of Photobiomodulation Therapy and Biological Dressings for Diabetic Foot Ulcers 揭示治疗潜力:糖尿病足溃疡的光生物调节疗法和生物敷料的系统综述

Journal of lasers in medical sciences Pub Date : 2023-10-28 DOI: 10.34172/jlms.2023.49

Sina Karimpour, Mohammad Hussein Amirmotamed, Fariborz Rashno, Foozhan Tahmasebinia, Aliasghar Keramatinia, Fatemeh Fadaee Fathabadi, Hojjat Allah Abbaszadeh, Shahram Darabi

{"title":"Unveiling Therapeutic Potential: A Systematic Review of Photobiomodulation Therapy and Biological Dressings for Diabetic Foot Ulcers","authors":"Sina Karimpour, Mohammad Hussein Amirmotamed, Fariborz Rashno, Foozhan Tahmasebinia, Aliasghar Keramatinia, Fatemeh Fadaee Fathabadi, Hojjat Allah Abbaszadeh, Shahram Darabi","doi":"10.34172/jlms.2023.49","DOIUrl":"https://doi.org/10.34172/jlms.2023.49","url":null,"abstract":"Introduction: Diabetes poses a global health challenge, giving rise to various complications, including diabetic foot ulcers (DFUs). DFUs, marked by ischemic ulcers susceptible to infection and amputation, underscore the urgency for innovative treatments. This study investigated the impact of photobiomodulation therapy (PBT) and autologous platelet gel (APG) on DFUs recovery. Methods: We systematically searched Web of Science, EMBASE, MEDLINE, Cochrane Library, Scopus, and Google Scholar (2015-2023) by using pertinent terms like \"photobiomodulation therapy,\" \"low level light therapy,\" and \"platelet gel.\" After meticulous data extraction and review, 57 articles were chosen and categorized. Among these, three randomized controlled trials involving 186 participants were selected for APG analysis. Results: Findings demonstrate that APG application carries minimal risk and offers promising improvements in healing time, grade, pain reduction, and granulation tissue formation. Similarly, diverse PBT modalities involving distinct probes and wavelengths exhibit the potential to enhance tissue perfusion, expedite healing, and impede wound progression, reducing the need for invasive interventions. Conclusion: PBT and APG emerge as valuable tools to augment wound healing, mitigate inflammation, and avert amputation, representing compelling therapeutic options for DFUs.","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136232484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Collagen Synthesis as a Prominent Process During the Interval between Two Laser Sessions 胶原蛋白合成在两次激光治疗间隔期间是一个突出的过程

Journal of lasers in medical sciences Pub Date : 2023-10-28 DOI: 10.34172/jlms.2023.50

Vahid Mansouri, Babak Arjmand, Maryam Hamzeloo-Moghadam, Mostafa Rezaei Tavirani, Zahra Razzaghi, Alireza Ahmadzadeh, Mitra Rezaei, Reza M Robati

{"title":"Collagen Synthesis as a Prominent Process During the Interval between Two Laser Sessions","authors":"Vahid Mansouri, Babak Arjmand, Maryam Hamzeloo-Moghadam, Mostafa Rezaei Tavirani, Zahra Razzaghi, Alireza Ahmadzadeh, Mitra Rezaei, Reza M Robati","doi":"10.34172/jlms.2023.50","DOIUrl":"https://doi.org/10.34172/jlms.2023.50","url":null,"abstract":"Introduction: Many people suffer from skin photodamage, especially photoaging. The application of a laser to repair damages is a common therapeutic method that is used widely. In the present study, the effectiveness and molecular mechanism of an Er:Glass non-ablative fractional laser on the human skin was assessed via bioinformatics and network analysis. Methods: The gene expression profiles of 17 white female forearm skins which received an Er:Glass non-ablative fractional laser before and after laser treatment in two sessions were extracted from Gene Expression Omnibus (GEO). Data were evaluated via GEO2R and the significant differentially expressed genes (DEGs) were assessed via protein-protein interaction (PPI) network analysis. The central nodes were identified and discussed for the compared set of samples. Results: Five classes of samples were clustered in two categories: first, baseline, 7 and 14 days after the first session of laser treatment, and second, one day after the first laser session, 29 days after the first laser session, and 1 day after the second laser session. The gross cell functions such as cell division and cell cycle and immune response were highlighted as the early affected targets of the laser. Collagen synthesis was resulted after the first laser session. Conclusion: In conclusion, the time interval between laser sessions plays a critical role in the effectiveness of laser therapy. Findings indicate that the gross effect of laser application appears in a short time, and important processes such as collagen synthesis happen later.","PeriodicalId":16224,"journal":{"name":"Journal of lasers in medical sciences","volume":"38 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136232485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Comparative Histological Study of Gingival Depigmentation by 808 and 445 nm Diode Lasers 808和445 nm二极管激光对牙龈色素脱色的组织学比较研究

Journal of lasers in medical sciences Pub Date : 2023-10-25 DOI: 10.34172/jlms.2023.48

Seyed Masoud Mojahedi Nasab, Matthias Frentzen, Somayeh Rahmani, Fahimeh Anbari, Saranaz Azari-Marhabi, Jörg Meister, Deniz Mojahedi Nasab

引用次数: 0