Journal of Indian Society of Periodontology最新文献

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Evaluation of the cortication ratio and visibility of mandibular canal and mandibular incisive canal in patients with mandibular cortical index type 1 on cone-beam computed tomography images.
Journal of Indian Society of Periodontology Pub Date : 2024-07-01 Epub Date: 2025-01-06 DOI: 10.4103/jisp.jisp_275_23
Roghieh Bardal, Ahad Alizadeh, Vahid Nouri, Mohammad Salehi
{"title":"Evaluation of the cortication ratio and visibility of mandibular canal and mandibular incisive canal in patients with mandibular cortical index type 1 on cone-beam computed tomography images.","authors":"Roghieh Bardal, Ahad Alizadeh, Vahid Nouri, Mohammad Salehi","doi":"10.4103/jisp.jisp_275_23","DOIUrl":"10.4103/jisp.jisp_275_23","url":null,"abstract":"<p><strong>Background: </strong>Mandibular canal visibility (MCV) is important to determine the relative position of the mandibular canal (MC) before any invasive surgery. It depends on the cortication ratio (CR) of the canal's superior border. This study aimed to evaluate the MCV and CR in patients with mandibular cortical index 1 (MCI1).</p><p><strong>Materials and methods: </strong>In this retrospective study, 132 mandibular cone-beam computed tomography images of patients with MCI1 were evaluated. 6-point rating MCV score and CR were determined for cross-sections of the MC in the following areas: incisive canal (INC), mental foramen and canal (MF), first premolar to the third molar (1PM, 2PM, 1M, 2M, and 3M), and the corresponding edentulous areas (E1PM-E3M). 1PM was overlapped with MF in most cases. An MCV score1 (excellent visibility) and 2PM area were considered reference levels.</p><p><strong>Results: </strong>Sex and age did not significantly affect the MCV score or CR (<i>P</i> > 0.05). 98.6% of the INC and 92.31%-100% of the MC were visible. The mean ± SD of the CR in the INC and MC was 0.86 (0.23) and 0.77 (0.29), respectively. The estimated difference in the mean CR was statistically significant only between the INC area and dentulous areas (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Despite the higher presence probability of score 2 in the 1M relative to 2PM, there was no significant decrease in the visible cases and CR of this area. Invisible cases were significantly lower in the INC, MF, and 3M areas.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 4","pages":"449-455"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143523560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative evaluation of oral hygiene status by using oral hygiene index, simplified oral hygiene index, and modified oral hygiene index: Revalidation of modified oral hygiene index.
Journal of Indian Society of Periodontology Pub Date : 2024-07-01 Epub Date: 2025-01-06 DOI: 10.4103/jisp.jisp_399_23
Subhash Garg, Sumbul Nasir
{"title":"Comparative evaluation of oral hygiene status by using oral hygiene index, simplified oral hygiene index, and modified oral hygiene index: Revalidation of modified oral hygiene index.","authors":"Subhash Garg, Sumbul Nasir","doi":"10.4103/jisp.jisp_399_23","DOIUrl":"10.4103/jisp.jisp_399_23","url":null,"abstract":"<p><strong>Background: </strong>Good oral hygiene is a critical component of overall oral health. Various methods have developed over time to assess oral hygiene status. In 1960, Greene and Vermillion introduced the Oral Hygiene Index (OHI), which assessed debris and calculus on 12 tooth surfaces. In 1964, they proposed a Simplified Oral Hygiene Index (OHI-S), which evaluated only 6 surfaces of six index teeth. The authors recommended the OHI-S due to its faster clinical assessments but concluded that it was less sensitive than the OHI despite both indices being sufficiently sensitive. In 1987, Garg S introduced the Modified Oral Hygiene Index (OHI-M), which provides a more comprehensive evaluation by assessing debris and calculus on the facial (buccal/labial), oral (palatal/lingual), and specifically occlusal surfaces of each fully erupted permanent tooth. The OHI-M is a reliable and sensitive method for accurately evaluating oral hygiene status.</p><p><strong>Aim: </strong>This study aims to comparatively evaluate oral hygiene status using OHI, OHI-S, and OHI-M and revalidate the OHI-M.</p><p><strong>Materials and methods: </strong>221 patients (119 males and 102 females) were randomly selected through simple random sampling. A single investigator performed the scoring. The sample size was determined based on a 95% confidence level. The collected data were analyzed using IBM SPSS Statistics, and Pearson's correlation test was employed to assess the correlations.</p><p><strong>Results: </strong>The mean and standard deviation of the OHI-M were found to be the lowest (2.55 ± 0.82) compared to the OHI (7.13 ± 1.79) and OHI-S (3.23 ± 0.99). It indicates that the variation in OHI-M values is smaller than that in OHI and OHI-S. Positive correlations were observed among the three indices, with a statistically significant result (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>The OHI-M is found to be the most sensitive scoring method for evaluating oral hygiene status compared to the OHI and OHI-S. These results further confirm the validity of OHI-M.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 4","pages":"461-467"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143523579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Negligence of gingival overgrowth leading to loss of entire dentition.
Journal of Indian Society of Periodontology Pub Date : 2024-07-01 Epub Date: 2025-01-06 DOI: 10.4103/jisp.jisp_147_23
Monali Shah, Vandana Shah, Megha Ellu Poojari, Nishanta Bora
{"title":"Negligence of gingival overgrowth leading to loss of entire dentition.","authors":"Monali Shah, Vandana Shah, Megha Ellu Poojari, Nishanta Bora","doi":"10.4103/jisp.jisp_147_23","DOIUrl":"10.4103/jisp.jisp_147_23","url":null,"abstract":"<p><p>Drug-induced gingival enlargement often occurs due to patient's lack of awareness about the side effects of prescribed medications. This case report details an unusual instance of massive drug-induced gingival overgrowth in a 50-year-old female, successfully managed through a multidisciplinary approach, including surgical intervention and prosthetic rehabilitation. The surgical treatment involved multiple extractions and the excision of excessive tissue. Both arches healed completely after surgery, and the patient underwent prosthetic rehabilitation, with no signs of recurrence. Effective management of such cases relies on patient counseling and appropriate drug substitution. Increasing awareness about the side effects of certain medications and the connection between systemic and oral health is crucial to prevent such cases of gingival enlargement.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 4","pages":"494-498"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143523603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glycemic control in patients with type 1 diabetes mellitus affects periodontal health but not salivary status: An observational study.
Journal of Indian Society of Periodontology Pub Date : 2024-07-01 Epub Date: 2025-01-06 DOI: 10.4103/jisp.jisp_365_23
Paula de Oliveira Cunha, Isadora Messias Batista Rosa, Adriana Campos Passanezi Sant'ana, Mariana Schutzer Ragghianti Zangrando, Carlos Antonio Negrato, Carla Andreotti Damante
{"title":"Glycemic control in patients with type 1 diabetes mellitus affects periodontal health but not salivary status: An observational study.","authors":"Paula de Oliveira Cunha, Isadora Messias Batista Rosa, Adriana Campos Passanezi Sant'ana, Mariana Schutzer Ragghianti Zangrando, Carlos Antonio Negrato, Carla Andreotti Damante","doi":"10.4103/jisp.jisp_365_23","DOIUrl":"10.4103/jisp.jisp_365_23","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this observational study was to assess the periodontal and salivary status of patients with type 1 diabetes mellitus (T1DM).</p><p><strong>Materials and methods: </strong>Thirty patients were divided into a test group (DM1G - T1DM, <i>n</i> = 15) and a control group (CG - normoglycemic, <i>n</i> = 15). Periodontal clinical parameters were evaluated using probing depth (PD), bleeding on probing (BOP), clinical attachment level (CAL), and plaque index (PI). Salivary tests assessed pH, buffering capacity, salivary glucose, and peroxidase activity. Capillary blood glucose was recorded for all patients, and glycated hemoglobin (HbA1c) was measured only for patients with T1DM. Statistical analysis was performed using Student's <i>t</i>-test and Pearson's correlation coefficient (<i>P</i> < 0.05).</p><p><strong>Results: </strong>The results showed significantly higher PI and BOP values in DM1G (<i>P</i> < 0.01). Positive correlations were found between HbA1c, PI, and BOP (<i>P</i> < 0.01). Capillary blood glucose levels differed between groups (<i>P</i> < 0.01). Positive correlations between capillary blood glucose, PD, and CAL were found only in the CG (<i>P</i> < 0.01). No significant differences were observed between the groups for salivary parameters (<i>P</i> > 0.05).</p><p><strong>Conclusions: </strong>Patients with T1DM exhibit poorer periodontal conditions compared to normoglycemic individuals, although no significant differences were found in salivary parameters between the two groups.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 4","pages":"456-460"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143523564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maxillary mucormycosis masquerading as an endodontic-periodontal lesion.
Journal of Indian Society of Periodontology Pub Date : 2024-07-01 Epub Date: 2025-01-06 DOI: 10.4103/jisp.jisp_89_24
Abubacker Afreen Jannath, Krishnan Viswanathan, Sambanthan Thiruneelakandan, Rajasekar Sundaram, Srinivasan Sivapragasam
{"title":"Maxillary mucormycosis masquerading as an endodontic-periodontal lesion.","authors":"Abubacker Afreen Jannath, Krishnan Viswanathan, Sambanthan Thiruneelakandan, Rajasekar Sundaram, Srinivasan Sivapragasam","doi":"10.4103/jisp.jisp_89_24","DOIUrl":"10.4103/jisp.jisp_89_24","url":null,"abstract":"<p><p>Endodontic-periodontal (endo-perio) lesions are commonly encountered in dental clinics, with patients typically presenting with acute pulpal pain, often accompanied by abscess formation and tooth mobility. Management generally involves root canal treatment (RCT) and, if required, surgical intervention. This article discusses a notable case of a 43-year-old male patient who presented with a chief complaint of pain and loose teeth in the upper left back region for the past 3 weeks. Phase I periodontal therapy was initiated, followed by RCT of teeth #21 to #25. However, 2 weeks later, the patient presented with swelling, prompting surgical excision and biopsy. Histopathological analysis revealed nonseptate hyphae with right-angle branching, indicative of mucormycosis.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 4","pages":"484-488"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143523600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial intelligence - The future of periodontics and implant dentistry?
Journal of Indian Society of Periodontology Pub Date : 2024-07-01 Epub Date: 2025-01-06 DOI: 10.4103/jisp.jisp_507_24
Baljeet Singh
{"title":"Artificial intelligence - The future of periodontics and implant dentistry?","authors":"Baljeet Singh","doi":"10.4103/jisp.jisp_507_24","DOIUrl":"10.4103/jisp.jisp_507_24","url":null,"abstract":"","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 4","pages":"387-388"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143523570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Soft-tissue augmentation for increasing keratinized tissue around dental implants: A systematic review.
Journal of Indian Society of Periodontology Pub Date : 2024-07-01 Epub Date: 2025-01-06 DOI: 10.4103/jisp.jisp_429_23
Farjad Zafar, Maryam Riaz, Rafay Ahmed, Rahul Kumar
{"title":"Soft-tissue augmentation for increasing keratinized tissue around dental implants: A systematic review.","authors":"Farjad Zafar, Maryam Riaz, Rafay Ahmed, Rahul Kumar","doi":"10.4103/jisp.jisp_429_23","DOIUrl":"10.4103/jisp.jisp_429_23","url":null,"abstract":"<p><strong>Background: </strong>This systematic review aims to comprehensively assess the efficacy of soft-tissue augmentation procedures in enhancing the width of keratinized mucosa (KM) surrounding implants with compromised soft-tissue status.</p><p><strong>Materials and methods: </strong>A thorough search was conducted on MEDLINE through PubMed and EMBASE via Ovid, supplemented by manual article searches. Inclusion criteria comprised human studies published in English within the past decade (up to July 2023), focusing on soft-tissue grafting techniques for augmenting keratinized mucosal width. The Joanna Briggs Institute critical appraisal tools were employed to evaluate the risk of bias in selected studies.</p><p><strong>Results: </strong>The review includes 27 studies, comprising nine prospective clinical studies, 13 randomized controlled trials (RCTs), and 5 case series. Notably, interventions demonstrated an augmented KM ranging from 0.89 mm to 7.7 mm. Optimal outcomes were observed with apically positioned partial-thickness flaps and vestibuloplasty (VP) utilizing xenogeneic collagen matrix (XCM) or free gingival graft (FGG). However, heterogeneity in study designs precluded meta-analysis.</p><p><strong>Conclusion: </strong>Despite the limitations, this study emphasizes the potential to augment KM width through apically positioned partial-thickness flaps and VP techniques employing XCM or FGG. Further RCTs with extended follow-up are needed to refine treatment approaches, improve outcomes, and address gaps in understanding graft integration mechanisms and strategies to minimize graft shrinkage.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 4","pages":"417-426"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864333/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143523610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"Interdental cleansing:" A neglected side dish in oral hygiene maintenance. “洗牙”:口腔卫生保养中被忽视的小菜。
Journal of Indian Society of Periodontology Pub Date : 2024-05-01 Epub Date: 2024-12-02 DOI: 10.4103/jisp.jisp_379_24
Dharmarajan Gopalakrishnan
{"title":"\"Interdental cleansing:\" A neglected side dish in oral hygiene maintenance.","authors":"Dharmarajan Gopalakrishnan","doi":"10.4103/jisp.jisp_379_24","DOIUrl":"10.4103/jisp.jisp_379_24","url":null,"abstract":"","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 3","pages":"281-282"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11684579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142915190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative evaluation of coronally advanced flap and semilunar coronally repositioned flap, using platelet-rich fibrin in Miller's Class I recession defects: A randomized clinical trial. 一项随机临床试验:利用富血小板纤维蛋白治疗Miller's I类退行性缺损的冠状推进皮瓣和半月冠状再定位皮瓣的比较评价
Journal of Indian Society of Periodontology Pub Date : 2024-05-01 Epub Date: 2024-12-02 DOI: 10.4103/jisp.jisp_251_23
Sumbul Saifi, Shiva Shankar Gummaluri, Avantika Rani, Rayashettypura Gurushanth Shiva Manjunath
{"title":"Comparative evaluation of coronally advanced flap and semilunar coronally repositioned flap, using platelet-rich fibrin in Miller's Class I recession defects: A randomized clinical trial.","authors":"Sumbul Saifi, Shiva Shankar Gummaluri, Avantika Rani, Rayashettypura Gurushanth Shiva Manjunath","doi":"10.4103/jisp.jisp_251_23","DOIUrl":"10.4103/jisp.jisp_251_23","url":null,"abstract":"<p><strong>Background: </strong>For a periodontist, treating recession is always a proud moment and a challenging task. The current trial aimed at comparing and clinically evaluating semilunar coronally repositioned flap (SCRF) and coronally advanced flap (CAF) procedures combined with platelet-rich fibrin (PRF) in the management of Miller's Class I recession defects.</p><p><strong>Materials and methods: </strong>Thirty-six recession sites were randomly divided into the CAF or SCRF groups. Gingival thickness (GT), root coverage percentage (%RC), plaque index (PI), gingival bleeding index (GBI), and clinical attachment level (CAL) were measured at baseline and 3 and 6 months. Recession height (RH), recession width (RW), and width of keratinized tissue (WKT) were also measured. With significance set at <i>p</i>=/<0.05 and <0.001, the Chi-square test was used to analyze intragroup data and the paired <i>t</i>-test was used to analyze intergroup differences.</p><p><strong>Results: </strong>Intragroup comparison showed a statistical significance for all the clinical parameters i.e. RW (<i>P</i> = 0.00*), RD (<i>P</i> = 0.00*), CAL (<i>P</i> = 0.00*), and GT (<i>P</i> = 0.042*) of the CAF group except for PD (<i>P</i> = 1.00) and WKT (<i>P</i> = 0.331) whereas, the SCRF group showed statistical significance for WKT (<i>P</i> = 0.001*) and GT (<i>P</i> = 0.00*). Remaining parameters of SCRF group were non-significant when compared from baseline to 6 months (<i>P</i> > 0.05). Further, intergroup comparison showed no significant difference in both the groups for all the parameters except for %RC where significance was reported at 1 month (<i>P</i> = 0.015*) and 3 months (<i>P</i> = 0.013*) when compared from baseline to 6 months.</p><p><strong>Conclusion: </strong>Root coverage is better in CAF with PRF than SCRF with PRF, in the treatment of gingival recession. PRF helped in soft-tissue healing and increased in GT.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 3","pages":"360-367"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11684582/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142915194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Substance P-A neuropeptide regulator of periodontal disease pathogenesis and potential novel therapeutic entity: A narrative review. 物质P-A神经肽调节牙周病发病机制和潜在的新型治疗实体:叙述性综述。
Journal of Indian Society of Periodontology Pub Date : 2024-05-01 Epub Date: 2024-12-02 DOI: 10.4103/jisp.jisp_56_24
A Jayanthi, D Tiwari, L Puzhankara
{"title":"Substance P-A neuropeptide regulator of periodontal disease pathogenesis and potential novel therapeutic entity: A narrative review.","authors":"A Jayanthi, D Tiwari, L Puzhankara","doi":"10.4103/jisp.jisp_56_24","DOIUrl":"10.4103/jisp.jisp_56_24","url":null,"abstract":"<p><p>Substance P (SP), a neuropeptide primarily released by neurons, has emerged as a key player in the intricate network of factors governing periodontal inflammation, immune responses, bone metabolism, and tissue regeneration. Due to its multifaceted role, it may be explored for its potential participation in periodontal therapeutic strategies. The databases, PubMed/MEDLINE, and SCOPUS were searched for all published articles on SP, its role in inflammation, and periodontal disease. The following search terms, adapted to the specific database, were used; \"substance p AND periodontal *\" AND \"therapeutics\" and records were retrieved. All articles not pertaining to SP in periodontal health and disease were excluded from the study. The full texts of eligible articles were retrieved. Data on SP and its role in inflammation and in periodontal health, disease, and therapy were extracted and have been presented as a narrative review. SP manifests during inflammatory phase of periodontal disease and is one of the causes of bone loss. According to studies, the gingival crevicular fluid from areas with active periodontal disease and bone loss had the greatest levels of SP. These chemicals may linger long enough to trigger neurogenic inflammation and elicit pain in tissues that are vulnerable to it. SP expression during progression of periodontal disease might be a risk factor for individuals with systemic inflammatory diseases, such as chronic arthritis. However, SP may be manipulated to provide avenues for management of periodontal disease and thereby serve as therapeutic target.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 3","pages":"284-289"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11684568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142915208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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