{"title":"Indian Society of Periodontology Good Clinical Practice Recommendations for dental pain management and use of analgesics.","authors":"Vishakha Grover, Ashish Kumar, Anurag Satpathy, Ashish Jain, Neeraj Deshpande, Harpreet Singh Grover, Manish Khatri, Tanya Nandkeoliar, Ajit Nair, Amit Benjamin, Ashish Sham Nichani, Baljeet Singh, Bela Dilip Dave, Girish Bhutada, Gurparkash Singh Chahal, Kuldip Singh Sangha, Tirthankar Debnath, Trinath Kishore Damera, Vaibhav Karemore, Vidushi Sheokand, Vivek Kumar Bains","doi":"10.4103/jisp.jisp_131_26","DOIUrl":"10.4103/jisp.jisp_131_26","url":null,"abstract":"<p><p>Pain is one of the most frequent reasons for seeking dental care and significantly influences patient comfort, treatment acceptance, and clinical outcomes. Effective management of dental pain requires accurate diagnosis, timely intervention, and the rational use of analgesics supported by evidence-based clinical decision-making. Recognizing the need for structured guidance for everyday dental practice, the Indian Society of Periodontology has developed Good Clinical Practice Recommendations on Pain Management and the Use of Analgesics in Dental Clinics. These recommendations were formulated by a panel of nineteen subject matter experts from across the country following a comprehensive review of the available literature and structured consensus discussions. The document is organized into three key sections: Dental Pain - Diagnosis and Assessment, focusing on the clinical evaluation and characterization of dental pain; Multimodal Strategies for Pain Management in Dentistry, outlining pharmacological and non-pharmacological approaches for optimal pain control; and Clinical Decision Making in Dental Pain Management, which provides practical guidance on the rational and safe use of analgesics in routine clinical scenarios. The recommendations aim to support clinicians in selecting appropriate pain management strategies, encourage responsible prescribing practices, and promote patient-centred care. This document is intended to serve as a concise reference for dental practitioners and contribute to improving the quality and consistency of pain management in dental practice.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 1","pages":"6-37"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13286543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148308261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of an oxygen-releasing mouthwash on <i>Aggregatibacter actinomycetemcomitans</i> and HaCaT cells: A pilot study.","authors":"Ayyanahalli Matta Bharath Kumar, Swastik Mishra, Pratibha Gopalkrishna, Santhosh Kumar","doi":"10.4103/jisp.jisp_418_24","DOIUrl":"10.4103/jisp.jisp_418_24","url":null,"abstract":"<p><strong>Background: </strong>Oxygen-releasing oral care products are effective in treating ulcers, gingival disease, and root canal irrigation. The present <i>in vitro</i> study evaluated the antibacterial properties and biological effects of a commercially available oxygen-releasing mouthwash, Blue<sup>®</sup>M.</p><p><strong>Materials and methods: </strong>We compared Blue<sup>®</sup>M mouthwash with chlorhexidine (CHX) using the agar disk diffusion assay and minimum inhibitory concentration methods. Furthermore, 1 μL/mL of mouthwash was applied to HaCaT cells to assess its effects on cell migration using the scratch migration assay.</p><p><strong>Results: </strong>The zone of inhibition for the two mouthwash formulations was comparable. Blue<sup>®</sup>M mouthwash demonstrated the inhibition of <i>Aggregatibacter actinomycetemcomitans</i> (Aa) at 6.25 μg/mL, and 0.12% CHX was effective at 0.4 μg/mL. Blue<sup>®</sup>M (1 μL/mL) promoted HaCaT cell migration by up to 88.5% at 72 h compared to the control, with no adverse morphological changes.</p><p><strong>Conclusions: </strong>Blue<sup>®</sup>M was effective at inhibiting Aa and exhibited negligible cytotoxicity in HaCaT cells, with minimal effects on cell migration.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 1","pages":"73-79"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13286538/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148308286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lalitha V Kerudi, Vaishali Madhav Mane, Aarti Yashwant Patil, Veerendra V Kerudi
{"title":"Guided periodontal plastic surgery for the correction of gummy smile using data merging and computer-aided design and computer-aided manufacturing surgical guide.","authors":"Lalitha V Kerudi, Vaishali Madhav Mane, Aarti Yashwant Patil, Veerendra V Kerudi","doi":"10.4103/jisp.jisp_337_24","DOIUrl":"10.4103/jisp.jisp_337_24","url":null,"abstract":"<p><p>Excessive gingival display, often referred to as a gummy smile, presents a significant esthetic concern and often necessitates precise periodontal intervention. Esthetic crown lengthening is a technique-sensitive procedure, especially when both soft tissue and bone recontouring are required. This case report details the management of a gummy smile in a 25-year-old female patient using a digital workflow that includes data merging, digital smile design, and a computer-aided design and computer-aided manufacturing (CAD-CAM)-fabricated surgical guide. Comprehensive clinical examination, intraoral scanning, standardized photographs, and cone beam computed tomography data were combined to enable accurate diagnosis and virtual treatment planning. A customized CAD-CAM surgical guide was designed to direct gingival and osseous resection during esthetic crown lengthening. Guided periodontal plastic surgery was performed, followed by management of the defect in the maxillary anterior region. Postoperative healing was satisfactory, with a notable reduction in gingival display, stable periodontal parameters, and high patient satisfaction during follow-up visits. This case highlights the clinical benefits of digital workflows for achieving predictable esthetic results in treating gummy smiles.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 1","pages":"145-149"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13286588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148308319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Targeting periodontitis with shikonin: Molecular insights and therapeutic prospects - A narrative review.","authors":"Suchetha Aghanashini, Lakshmi Puzhankara, Asavari Desai","doi":"10.4103/jisp.jisp_151_25","DOIUrl":"10.4103/jisp.jisp_151_25","url":null,"abstract":"<p><p>Shikonin (SHI) is a naturally occurring naphthoquinone predominantly isolated from the roots of <i>Lithospermum erythrorhizon</i> and other species within the <i>Boraginaceae</i> family. Traditionally recognized for its therapeutic potential, SHI has garnered considerable scientific interest due to its broad pharmacological profile and relatively low toxicity. Together with its enantiomer alkannin, SHI shows anti-inflammatory, antibacterial, antioxidant, anticancer, wound-healing, and antithrombotic activities. Recent advancements in extraction technologies, notably ultrasound-assisted ionic liquid-aqueous two-phase systems, have achieved SHI yields of up to 97%, thereby enhancing its accessibility for pharmaceutical applications. SHI is biosynthesized in the endoplasmic reticulum of plant cells through the coordinated activity of the shikimate and mevalonate pathways, with cytochrome P450 enzymes playing a pivotal role in its synthesis. Its relevance in periodontology is increasingly recognized, owing to its capacity to inhibit osteoclastogenesis, promote periodontal tissue and bone regeneration, modulate host immune responses, and suppress pathogenic microorganisms such as <i>Porphyromonas gingivalis</i>. Moreover, SHI's inhibition of pyruvate kinase M2, a key regulator of glycolytic and inflammatory pathways, highlights its potential in the modulation of immunometabolic processes. A systematic search of PubMed, Web of Science, and Scopus using the keywords \"shikonin AND periodont*\" identified 384 publications. Following screening, 40 studies were selected and thematically categorized: SHI's pharmacological properties, its role in periodontal tissue homeostasis, and its therapeutic potential in clinical periodontology. In summary, SHI appears as a promising candidate for adjunctive periodontal therapy, meriting further investigation into its mechanistic actions and clinical applications in oral health preservation.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 1","pages":"38-44"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13286540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148308328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasonography-guided sclerotherapy for a benign vascular malformation of the attached gingiva.","authors":"Rahul Bhandary, Geethu Venugopalan, Khushi Shukla, Ruchi Ramanujan","doi":"10.4103/jisp.jisp_204_25","DOIUrl":"10.4103/jisp.jisp_204_25","url":null,"abstract":"<p><p>Oral vascular malformations (VMs) are nonproliferative lesions, characterized histologically by low cellularity and dilated vascular channels lined by mature endothelial cells. Unlike vascular tumors such as hemangiomas, they grow slowly and progressively and do not regress spontaneously. This report describes the rare case of a 24-year-old female with a benign VM involving the maxillary attached gingiva and buccal vestibule, presenting as a compressible intraoral swelling with extraoral fullness. Given the lesion's functional and esthetic implications, ultrasonography (USG)-guided sclerotherapy was selected as a minimally invasive treatment option. This approach was favored over surgical excision to minimize tissue trauma and preserve surrounding structures. A single session using polidocanol, a well-tolerated sclerosant, led to marked clinical regression without damage to adjacent periodontal structures. No recurrence or complications were observed during follow-up. This case highlights the precision, safety, and efficacy of USG-guided polidocanol sclerotherapy as a conservative, tissue-preserving alternative to surgical excision for the management of gingival VMs.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 1","pages":"154-159"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13286595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148308334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of the relationship between subgingival microbiome in obese and nonobese clinically healthy and periodontitis patients - An experimental study.","authors":"Supraja Govindarajan, Jaiganesh Ramamurthy","doi":"10.4103/jisp.jisp_35_25","DOIUrl":"10.4103/jisp.jisp_35_25","url":null,"abstract":"<p><strong>Background: </strong>This study investigates the association between obesity and the prevalence of periodontopathic bacteria in obese/overweight individuals and healthy/normal-weight individuals, focusing mainly on the red complex organisms in individuals with and without periodontitis.</p><p><strong>Materials and methods: </strong>A cross-sectional study was conducted with 14 participants (7 obese/overweight and 7 healthy weight individuals), further categorized into periodontitis and healthy periodontium groups. Body mass index and waist-to-hip ratio were measured, total cholesterol level was determined, and probing pocket depth was determined. Subgingival plaque samples were obtained and examined for the presence of <i>Tannerella forsythia</i>, <i>Porphyromonas gingivalis</i>, and <i>Treponema denticola</i> through the quantitative real-time polymerase chain reaction analysis.</p><p><strong>Results: </strong>Obese patients had a significant association with <i>P</i>. <i>gingivalis</i>. In contrast, <i>T</i>. <i>forsythia</i> and <i>T</i>. <i>denticola</i> numbers were not statistically significant. Five out of seven obese participants had periodontitis, compared to four out of seven participants in the healthy weight group.</p><p><strong>Conclusion: </strong>Within the limitations of this pilot cross-sectional study, obesity was associated with an increased prevalence of <i>P</i>. <i>gingivalis</i> in individuals with periodontitis. These findings suggest that obesity may have a possible association with alterations in the subgingival red complex bacterial profile. However, results should be interpreted cautiously, and larger longitudinal studies are required to confirm these observations.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 1","pages":"135-140"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13286585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148308227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kavita Chandrasekaran, Krishna Kripal, Sunil Kumar D Chavan
{"title":"A neoteric approach to regeneration of intrabony defects using curcumin gel versus bioactive glass as bone replacement material among South Indian population: A randomized controlled trial.","authors":"Kavita Chandrasekaran, Krishna Kripal, Sunil Kumar D Chavan","doi":"10.4103/jisp.jisp_403_24","DOIUrl":"10.4103/jisp.jisp_403_24","url":null,"abstract":"<p><strong>Background and objectives: </strong>The trend of using herbal bone replacement material for the regeneration of periodontal intrabony defects is still underexplored in clinical periodontal practice. As there remains a paucity in scientific information regarding this, the present study was carried out to evaluate and compare clinically and radiographically the effectiveness of curcumin gel and bioactive glass as a BRM in treating intrabony defects among the South Indian population.</p><p><strong>Materials and methods: </strong>A total of 60 intrabony defects were randomly divided into Group 1 (30 defects treated with curcumin gel) and Group 2 (30 defects treated with bioactive glass). All clinical and radiographic parameters were recorded at baseline, 3 months, 6 months, and 9 months.</p><p><strong>Results: </strong>All the clinical parameters showed statistically significant intragroup and intergroup improvement at the end of 9 months. There was a statistically significant volumetric bone fill of defect sites, which was 13.64 (61.19%) and 11.51 (49.36%) in Groups 1 and 2, respectively, at the end of 9 months.</p><p><strong>Conclusion: </strong>The present study indicates that curcumin gel has a great potential for bone regeneration in periodontal intrabony defects, along with minimum/no postsurgical side effects due to its herbal nature. Thus, it may serve as a natural alternative to synthetic BRMs.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 1","pages":"80-86"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13286536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148308450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Digital dentistry and artificial intelligence: Redefining the future of periodontal care.","authors":"Neeraj Deshpande","doi":"10.4103/jisp.jisp_144_26","DOIUrl":"https://doi.org/10.4103/jisp.jisp_144_26","url":null,"abstract":"","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 1","pages":"2-3"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13286529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148308307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Strategic beginnings: In to continued traditions.","authors":"Ashish Jain","doi":"10.4103/jisp.jisp_172_26","DOIUrl":"https://doi.org/10.4103/jisp.jisp_172_26","url":null,"abstract":"","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 1","pages":"4-5"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13286525/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148308330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of the relationship between periodontitis and anemia of chronic disease - A comparative study in smokers and smokeless tobacco users.","authors":"Pradhuman Verma, Kanika Gupta Verma","doi":"10.4103/jisp.jisp_211_25","DOIUrl":"10.4103/jisp.jisp_211_25","url":null,"abstract":"<p><strong>Background: </strong>Anemia of chronic disease (ACD) is the cytokine-mediated outcome of chronic inflammatory disorders. The present study was conducted to assess the hematological parameters in tobacco-associated periodontitis patients.</p><p><strong>Materials and methods: </strong>The <b>s</b>tudy included 120 males, aged 35-65 years. Out of total cases, 90 had periodontitis, and they were subdivided into Group I (<i>n</i> = 30): tobacco smoker (s), Group II (<i>n</i> = 30): tobacco chewer (s), Group III (<i>n</i> = 30): tobacco chewer (s) and smoker (s), and Group IV or control (<i>n</i> = 30): subjects without periodontitis and tobacco habits. After clinical examination, periodontitis was assessed using plaque index (PI), probing pocket depth (PD), gingival index (GI), and clinical attachment loss (CAL). Blood investigations, including hemoglobin, mean corpuscular hemoglobin (MCH), erythrocyte count, MCH concentration (MCHC), erythrocyte sedimentation rate (ESR), packed cell volume, serum ferritin, transferrin saturation, and total iron-binding capacity (TIBC), were also done.</p><p><strong>Results: </strong>Group III revealed the highest red blood cell (RBC) count, MCHC, hematocrit, MCH, TIBC, and transferrin saturation. A significant (<i>P</i> < 0.05) relation was found between study groups and controls in relation to RBC, ESR, serum ferritin, TIBC, and transferrin saturation. PI and PD scores were highest in Group III; GI and CAL scores were highest in Groups I and II, respectively. All periodontal parameters of the study groups were found significantly (<i>P</i> < 0.05) different from controls, except for the GI score in Groups II and III.</p><p><strong>Conclusion: </strong>Our study revealed that periodontitis should be considered as the causative factor for ACD. Thus, it is required to counsel patients regarding tobacco cessation for the effective management of periodontal diseases and controlling ACD.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 1","pages":"108-114"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13286542/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148308298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}