Sruthima N V S Gottumukkala, Mikkili Rajya Lakshmi, Gautami S Penmetsa, K S V Ramesh, Mohan Kumar Pasupuleti, Vivek Bypalli
{"title":"Scanning electron microscopic analysis of 5% glycolic acid as a novel alternative to 17% ethylenediaminetetraacetic acid in root biomodification: An <i>in vitro</i> study.","authors":"Sruthima N V S Gottumukkala, Mikkili Rajya Lakshmi, Gautami S Penmetsa, K S V Ramesh, Mohan Kumar Pasupuleti, Vivek Bypalli","doi":"10.4103/jisp.jisp_150_23","DOIUrl":"10.4103/jisp.jisp_150_23","url":null,"abstract":"<p><strong>Background: </strong>Nonsurgical periodontal therapy results in the formation of a smear layer which inhibits tissue regeneration. Root biomodification (RB) using various agents has been tried for the enhancement of new attachment formation. However, no substantial therapeutic advantages of currently available root conditioning agents have been reported emphasizing the need for additional biologically acceptable agents. Glycolic acid (GA) due to its antimicrobial nature and ability of initiation and proliferation of fibroblasts may potentially modify root surface enabling regeneration.</p><p><strong>Materials and methods: </strong>Eighty specimens from 40 single-rooted teeth were treated with 17% ethylenediaminetetraacetic acid (EDTA) and 5% GA and scanning electron microscopy analysis was done. The micrographs were examined for the evaluation of smear layer removal, total number of dentinal tubules, total number of patent dentinal tubules, mean diameter and surface area of dentinal tubules, and dentin erosion. Statistical analysis was done using unpaired <i>t</i>-test for intergroup comparison.</p><p><strong>Results: </strong>The efficacy of smear layer removal (<i>P</i> = 0.01) and dentin erosion (<i>P</i> = 0.042) was significantly better in the GA group. Both the groups showed no difference in dentinal tubule-related parameters.</p><p><strong>Conclusion: </strong>GA showed improved RB with greater smear layer removal and lesser dentin erosion, indicating its use as a potent alternative to the conventional EDTA root conditioning.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 1","pages":"79-83"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11232807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gingiva as the primary site of extrapulmonary tuberculosis: A rare case report with brief review of literature.","authors":"Nakkeeran Adhithya, Srinivasan Poovan Kirubanidhi Kennedy Babu, Grace Tara Paul, Kadathanadan Vachali Soorya","doi":"10.4103/jisp.jisp_134_23","DOIUrl":"10.4103/jisp.jisp_134_23","url":null,"abstract":"<p><p>Multiple strains of Mycobacteria cause tuberculosis (TB), a chronic, specific infectious granulomatous disease. It mainly occurs with pulmonary involvement when compared to extrapulmonary involvement. Primary oral occurrence is uncommon and oral lesions are usually secondary to pulmonary involvement. When there are no active pulmonary clinical manifestations of TB, the diagnosis of the very rare entity of primary gingival TB poses a great challenge to clinicians. In this case report, we discuss a case of primary gingival TB in a 24-year-old lactating mother. This article briefs the onset and course of the lesion during pregnancy and postpartum, elaborates the pathway to diagnosis, various investigations performed and the regimen of antitubercular therapy for 6 months, followed by complete resolution of the lesion without recurrence. This report also describes the significance of considering TB as a differential diagnosis in oral lesions and the various diagnostic methods available. It also emphasizes the sole importance of histopathology in the early detection of the lesion and its management.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 1","pages":"132-137"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11232812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative evaluation of thermal impact of 980nm diode laser on soft tissue using irrigation and non-irrigation systems: A histomorphometric study.","authors":"Bharmappa Radhika, Sharath Wodeyar Shivaswamy, Amit Walvekar, Kunaal Dhingra, Rashmi Somashekhar Pattanshetty, Raju Shashidara","doi":"10.4103/jisp.jisp_218_23","DOIUrl":"10.4103/jisp.jisp_218_23","url":null,"abstract":"<p><strong>Background: </strong>Diode laser is one of the most captivating technologies in dental practice. In periodontics, when used at appropriate settings, it possesses the best properties for selective surgical and nonsurgical procedures such as subgingival calculus removal without a thermal change of the root surface, and also provides tissue surface sterilization. However, lasers always produce a certain amount of thermal damage to the soft tissues. Therefore, this study aimed to comparatively evaluate the thermal impact of 980-nm diode laser incisions, when used with irrigation versus nonirrigation systems.</p><p><strong>Materials and methods: </strong>The study was conducted on 24 gingival tissue samples obtained from the goat's mandible and maxilla. The samples were divided into two groups of 12 samples each, and laser incisions were given in 4 power settings, using 980-nm diode laser in super short pulse mode, with and without saline irrigation. Martius Scarlet Blue staining technique was used to prepare the histological slides. Then, slides were examined under a research microscope (Olympus CX 21), and the pictures of the slides were taken by mounting the camera onto the microscope mobile mount. The microscopic images hence obtained were analyzed for the depth and width of the incisions, area of carbonization, necrosis, and reversible damage, using the Digimizer image analysis software.</p><p><strong>Results: </strong>The results of this study demonstrated that the mean incision depth was higher (592.49 ± 180.97, <i>P</i> < 0.05), with less carbonization (25.52 ± 29.21, <i>P</i> = 0.00) and less necrosis (311.63 ± 156.441, <i>P</i> < 0.05) in the laser incisions with irrigation, as compared to the laser incisions given without irrigation system.</p><p><strong>Conclusion: </strong>Within the limitations of this study, it can be concluded that using an irrigation system causes less collateral damage while maintaining the incising efficiency of the diode laser. Further studies with a higher sample size, controlled irrigation systems, and incision techniques are needed to evaluate the efficiency of diode lasers for the clinical explanation of the results.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 1","pages":"91-98"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11232811/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Peri-implant diseases: \"Are we ready to take the epidemic in the offing - Head on\".","authors":"Baljeet Singh","doi":"10.4103/jisp.jisp_115_24","DOIUrl":"10.4103/jisp.jisp_115_24","url":null,"abstract":"","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11232809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aishwarya Madhukar Kale, Kunal S Sethi, Swapna A Mahale, Prerna A Karde, Lata Madhukar Kale, Sneha H Choudhary
{"title":"Comparative analysis of platelet-rich fibrin membrane and 0.2% hyaluronic acid gel on healing following gingival depigmentation procedure.","authors":"Aishwarya Madhukar Kale, Kunal S Sethi, Swapna A Mahale, Prerna A Karde, Lata Madhukar Kale, Sneha H Choudhary","doi":"10.4103/jisp.jisp_291_22","DOIUrl":"10.4103/jisp.jisp_291_22","url":null,"abstract":"<p><strong>Introduction: </strong>Platelet-rich fibrin (PRF) accelerates wound healing by promoting faster cicatricial tissue remodeling and excellent neovascularization. Hyaluronic acid (HA) being biocompatible, anti-inflammatory, and proangiogenic leads to improvement in the rate of wound healing.</p><p><strong>Aim: </strong>The aim of this study was to compare the effect of PRF membrane and 0.2% HA gel on wounds after gingival depigmentation surgery.</p><p><strong>Materials and methods: </strong>This study was carried out on 30 systemically healthy individuals recruited from the pool of patients who visited the department of periodontology. After depigmentation procedure in every patient, the sites were divided into three even groups. Group A received PRF membrane and periodontal dressing, Group B received 0.2% HA gel application and periodontal dressing, and Group C served as a control group in which only periodontal dressing was placed. The individuals were evaluated for the healing index (HI) and Numerical Rating Scale (NRS) on the 3<sup>rd</sup> and 5<sup>th</sup> day. Epithelialization test (ET) was performed on the 5<sup>th</sup> day. Gingival biotype was reassessed and compared to preoperative value after 3 months. The clinical trial was expressed in terms of mean and standard deviation. Intra-group comparison and inter-group comparison were done through the Kruskal-Wallis ANOVA test. All statistical tests were performed through SPSS version 25.0 (IBM).</p><p><strong>Results: </strong>The inter-group statistical analysis concerning NRS, HI, and ET showed statistically significant results in Groups A and B compared to Group C (<i>P</i> < 0.05), while gingival biotype showed statistically significant results in Group A compared to Groups B and C.</p><p><strong>Conclusion: </strong>The use of PRF membrane and HA gel to protect the raw wound site of depigmented gingiva proved to be an effective approach, resulting in faster healing.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 6","pages":"636-641"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparing the effectiveness of water flosser and dental floss in plaque reduction among adults: A systematic review.","authors":"Subhashree Mohapatra, Ladusingh Rajpurohit, Rahul Mohandas, Sujeet Patil","doi":"10.4103/jisp.jisp_597_22","DOIUrl":"10.4103/jisp.jisp_597_22","url":null,"abstract":"<p><strong>Introduction: </strong>Interdental aids such as dental floss and water flossers have been found to be effective in removing interdental plaque. This systematic review aimed to compare the available data on the efficacy of dental floss and water flossers in plaque removal among adults.</p><p><strong>Materials and methods: </strong>Five databases: PubMed, Scopus, Cochrane, ScienceDirect, Lilac, and Google Scholar were searched from January 1, 2002, to October 31, 2022, to obtain the relevant articles. Based on the search strategy, the titles of the studies were screened independently by two reviewers. Randomized controlled trials were included in the review, in which the study participants were given either dental floss or water flosser. Reduction in plaque scores was the outcome that was assessed. Seven articles met the eligibility criteria and were further processed for qualitative analysis.</p><p><strong>Results: </strong>The majority of the studies favored water flossers over dental floss in plaque reduction. Water flosser was also found to be effective in removing plaque from inaccessible interproximal areas of the tooth surfaces as compared to dental floss.</p><p><strong>Conclusion: </strong>Based on the scope of this review, results suggest that water flossers can be used as an effective alternative to dental floss in patients with manual dexterity, patients undergoing orthodontic treatment, and patients with dental prostheses.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 6","pages":"559-567"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Indian Society of Periodontology Scientific Events.","authors":"","doi":"10.4103/jisp.jisp_484_23","DOIUrl":"https://doi.org/10.4103/jisp.jisp_484_23","url":null,"abstract":"","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 6","pages":"655-658"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariane Cristina Sloniak, Ana Paula Lepique, Laís Yumi Souza Nakao, Cristina Cunha Villar
{"title":"Alterations in macrophage polarization play a key role in control and development of periodontal diseases.","authors":"Mariane Cristina Sloniak, Ana Paula Lepique, Laís Yumi Souza Nakao, Cristina Cunha Villar","doi":"10.4103/jisp.jisp_75_23","DOIUrl":"10.4103/jisp.jisp_75_23","url":null,"abstract":"<p><p>Periodontitis is a chronic inflammatory disease driven by complex interplays between a dysbiotic oral microbiome and a dysregulated host inflammatory response that results in the destruction of the tooth-supporting apparatus. Among the inflammatory cells involved in the pathogenesis of periodontitis, macrophages are recruited early on to sites of periodontal infection. These cells can polarize in different phenotypes that mediate the initiation and resolution of inflammatory responses, as well as in tissue healing. Macrophage phenotypic plasticity is thought to play a critical role in the induction and resolution of inflammation and may be compromised in patients with chronic inflammatory diseases. Here, we reviewed the role of macrophage polarization in periodontal disease and therapy.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 6","pages":"578-582"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906788/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical efficacy of 1% metformin gel around conventionally placed dental implants: A 9-month follow-up study.","authors":"Govardhani Krishnakumar, Sitamahalakshmi Koppu, Jampani Narendra Dev, Vajra Madhuri Songa, Lahari Buggapati, Radhika Mandrachalam","doi":"10.4103/jisp.jisp_534_22","DOIUrl":"10.4103/jisp.jisp_534_22","url":null,"abstract":"<p><strong>Aim: </strong>The study aimed to compare the clinical and radiographic outcomes of bone volume, density, and crestal bone levels in conventionally placed dental implants with and without local application of 1% metformin (MF) gel using cone-beam computed tomography (CBCT) at 9 months.</p><p><strong>Materials and methods: </strong>Twenty implants were placed in 18 individuals, randomly divided into 2 groups where Group A received a local application of 1% MF gel along with implant placement. In contrast, Group B received implant placement alone. After thorough clinical examination and preoperative CBCTs, implants were placed under aseptic conditions. Patients were recalled at 3 and 9 months after surgery. Implants were functionally loaded by the end of 3<sup>rd</sup> month. Soft-tissue parameters such as modified plaque index and modified sulcular bleeding index were recorded along with CBCT evaluation to assess the crestal bone loss, bone density measurement, and bone volume, postoperatively. Fisher's extract test, independent and paired <i>t</i>-test, and Bonferroni analysis were used to determine statistical significance with <i>P</i> ≤ 0.05.</p><p><strong>Results: </strong>There was no discernible difference between the groups regarding soft-tissue parameters, bone density, and crestal bone levels. However, comparing bone volume between the test and control groups at 9 months was statistically significant. The test group with 1% MF gel showed increased bone volume around the implant.</p><p><strong>Conclusion: </strong>The data obtained were strong enough to suggest that 1% MF gel administered locally can increase peri-implant bone volume, possibly due to its additional property favoring osteoblastic stimulation and proliferation.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 6","pages":"626-635"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Zimmermann-Laband syndrome-associated hereditary gingival fibromatosis.","authors":"Jaishree Tukaram Kshirsagar, Kalaiselvan Dharani, Priyangha Thangavel","doi":"10.4103/jisp.jisp_582_22","DOIUrl":"10.4103/jisp.jisp_582_22","url":null,"abstract":"<p><p>Hereditary gingival fibromatosis (HGF) is an uncommon slow-growing fibrous overgrowth characterized by connective tissue accumulation. It presents as an isolated feature or as a manifestation of any syndrome. Various syndromes associated with HGF are inherited by autosomal dominant/recessive/X-linked traits. Zimmermann-Laband syndrome (ZLS) is a rare, autosomal dominant inherited disease manifested with gingival fibromatosis (GF), nose and ears abnormalities, and hypoplastic/dysplastic nails or terminal phalanges of hand and feet. Although the pattern of inheritance was found to be both autosomal dominant and recessive traits, the molecular basis is still unclear. This report presents a possible case of ZLS-associated HGF in a 25-year-old female patient who presents with GF, hypertrichosis, and other syndrome-related features. Her father was similarly affected whereas her mother and sibling were asymptomatic. The patient and her family members were explained about the condition and surgical periodontal therapy was carried out for the patient to improve esthetics and was followed up regularly. Esthetics was significantly improved and no recurrence was noted at the end of 6 months.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 6","pages":"645-650"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}