Aditi Singh, Soumya Bardvalli Gururaj, Shrinidhi Maji Shankar, Chethana Kunthur Chidambar, Kala Bhushan, Bharathi Poojary
{"title":"Effect of LASER photobiomodulation on the cell viabilities of periodontal ligament fibroblasts of older and younger individuals - An <i>in vitro</i> study.","authors":"Aditi Singh, Soumya Bardvalli Gururaj, Shrinidhi Maji Shankar, Chethana Kunthur Chidambar, Kala Bhushan, Bharathi Poojary","doi":"10.4103/jisp.jisp_167_22","DOIUrl":"10.4103/jisp.jisp_167_22","url":null,"abstract":"<p><strong>Background and objectives: </strong>Fibroblasts form the major cell type of the periodontal ligament and most often studied for periodontal regeneration. The aim of the present study was to investigate the effects of photobiomodulation (PBM) on aged periodontal fibroblasts and compare the viability of periodontal fibroblasts of older and younger individuals.</p><p><strong>Materials and methods: </strong>A total of 32 patients were divided into four groups: A, B, C, and D. Groups A and C and B and D comprised of extracted teeth of older (>60 year) and younger individuals (<25 year), respectively. Extracted teeth from Groups A and B received PBM, (diode laser, 660 nm, 100 mW at 4J) whereas Groups C and D did not. Tissue from extracted teeth of all groups was processed and cultured and subjected to 3-(4,5 dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay to assess their viability.</p><p><strong>Results: </strong>The difference between the groups in terms of viability was significant (<i>P</i> < 0.0001). The mean viability of A and B (PBM) was 1.04 and 1.19, respectively. The mean viability for C and D (non-PBM) was 0.95 and 0.85, respectively.</p><p><strong>Conclusion: </strong>Older fibroblasts have lower viability than younger fibroblasts. PBM improves viability in both older and younger fibroblasts and more so in younger fibroblasts. However, more than one PBM would be required to sustain the effect longer.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 5","pages":"465-470"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538507/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41134824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Indian contributions to dental research.","authors":"Abhay P Kolte","doi":"10.4103/jisp.jisp_318_23","DOIUrl":"10.4103/jisp.jisp_318_23","url":null,"abstract":"","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 5","pages":"447-448"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41134825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vikender Singh Yadav, Nitika Monga, Nisha K Jose, Harsh Priya
{"title":"Evidence-based suggestions to improve the methodological issues in reporting of prevalence studies on gingival recession.","authors":"Vikender Singh Yadav, Nitika Monga, Nisha K Jose, Harsh Priya","doi":"10.4103/jisp.jisp_400_22","DOIUrl":"10.4103/jisp.jisp_400_22","url":null,"abstract":"<p><p>Gingival recession (GR) is considered a public health problem which is highly prevalent across different populations. Accuracy of psychometric properties of prevalence estimates of GR reported in epidemiological studies is important to facilitate setting public health goals, planning of public health programs, implementation of best practices and thereby developing public health policy. However, the reported prevalence estimates are influenced by the methodological variations among different studies, as observed in our recently published systematic review and meta-analysis on the global prevalence of GR. It substantially limits the comparability between studies and inferences about the true global variation in the prevalence of GR are difficult to establish. To address these issues, this commentary suggests to follow the standardized principles related to study design, clinical examination protocol, and characteristics of study subjects in future epidemiological studies on prevalence estimates of GR. Furthermore, the inclusion of additional domains in the reporting data is suggested for a deeper insight into the patterns of GR in different populations. Our suggestions are derived from a pragmatic approach and their consistent implementation would improve the reporting quality and achieve uniformity in future studies, thus benefitting the research in this area.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 5","pages":"461-464"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41128686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dantala Satyanarayana, Suhas Kulkarni, Dolar Doshi, Madupu Padma Reddy, Sana Khaled, Adepu Srilatha
{"title":"Periodontal health status among chronic obstructive pulmonary disease with age- and gender-matched controls.","authors":"Dantala Satyanarayana, Suhas Kulkarni, Dolar Doshi, Madupu Padma Reddy, Sana Khaled, Adepu Srilatha","doi":"10.4103/jisp.jisp_479_22","DOIUrl":"10.4103/jisp.jisp_479_22","url":null,"abstract":"<p><strong>Background: </strong>Periodontal disease and chronic obstructive pulmonary disease (COPD) share a pathogenic mechanism that involves activating and using inflammatory cytokines and neutrophils, which generate pathological changes in various tissues with a chronic degenerative outcome.</p><p><strong>Aim: </strong>the aim of this study was to assess and compare the periodontal health status among COPD patients with age- and gender-matched controls.</p><p><strong>Materials and methods: </strong>All the patients aged >30 years who were diagnosed with COPD by the physician were included as cases, while people who are apparently healthy and age and gender matched with cases were included as controls. Data on demographic details, socioeconomic status (Kuppuswamy scale), deleterious oral habits, and oral hygiene practices were obtained. The Simplified Oral Hygiene Index (OHI-S) and the WHO basic oral health survey proforma (1997) were used to obtain the data on oral hygiene and periodontal status respectively.</p><p><strong>Results: </strong>Most cases had moderate COPD severity (58.25%). The overall mean OHI-S, CPI, and LOA were higher among cases (3.92 ± 0.95, 3.68 ± 0.60, and 2.33 ± 1.10, respectively) in comparison to controls. Further, among cases, the mean oral hygiene and periodontitis increased with increased severity of COPD. Although among both cases and controls, gender, tobacco use, and alcohol consumption influenced their periodontal status, significant odds of higher risk were seen only among cases. Further, subjects with COPD had higher odds of having poor oral hygiene, deeper pocket depths, and LOA.</p><p><strong>Conclusion: </strong>A strong association between COPD and periodontitis was observed. The oral hygiene and periodontal disease worsened with the severity of COPD.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 5","pages":"524-529"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41147660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adjunctive benefit of probiotic supplementation along with nonsurgical therapy for peri-implant diseases - A systematic review and meta-analysis.","authors":"R Ambili, Nias Bin Nazimudeen","doi":"10.4103/jisp.jisp_308_22","DOIUrl":"10.4103/jisp.jisp_308_22","url":null,"abstract":"<p><p>Peri-implant diseases are prevalent conditions, but a predictable management strategy is still lacking. The objective of the present article was to evaluate the adjunctive benefits of probiotics with nonsurgical therapy in the management of peri-implant diseases. The review protocol was registered in PROSPERO and prepared according to PRISMA guidelines. Randomized controlled clinical trials in patients diagnosed with the peri-implant disease where probiotic was used as an adjunct to nonsurgical therapy were included in the study. The risk difference of percentage reduction in bleeding on probing, plaque accumulation, and mean difference in probing pocket depth reductions at implant level were estimated using a random effect model due to high heterogeneity among studies. Four studies fulfilled the criteria for selection. Two of them presented data on both peri-implantitis and peri-implant mucositis and they were considered separate studies during meta-analysis. Significant reduction in percentage of bleeding on probing was noticed at 1 and 3 months (-0.28 [-0.48, -0.09], <i>P</i> = 0.004 and - 0.19 [-0.35, -0.02], <i>P</i> = 0.03, respectively), but the reduction was not statistically significant at 6 months. Similar results were also observed for plaque accumulation. No statistically significant reduction in probing pocket depth was observed in the probiotic group during any of the re-evaluations.</p><p><strong>Conclusion: </strong>Adjunctive therapy of probiotics may improve the efficacy of nonsurgical therapy of peri-implant diseases for up to 3 months. However, moderate certainty was observed for a reduction in bleeding on probing after 1-month re-evaluation alone.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 4","pages":"352-361"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10049992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Crestal sinus augmentation in a head back position: Retrospective case series.","authors":"Yuhang Zhang, Chunyuan Zhang","doi":"10.4103/jisp.jisp_229_22","DOIUrl":"10.4103/jisp.jisp_229_22","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the clinical efficacy of Crestal Sinus Augmentation (CSA) in a head back position (CSA-HBP) for maxillary sinus mucosa elevation.</p><p><strong>Materials and methods: </strong>We enrolled 209 patients, 246 maxillary sinuses, 348 sites in this study. Complications, maxillary sinus mucosal perforation rate and cumulative survival rate (CSR) data were collected to evaluate the clinical efficacy of CSA-HBP. Maxillary sinus mucosal elevation height (EH) and new bone height (NH) were measured by cone-beam computerized tomography and standard periapical radiographs. The implantation sites of residual bone height (RBH) ≤5 mm and RBH >5 mm were marked as Groups A (<i>n</i> = 81) and B (<i>n</i> = 267), respectively. The implantation sites of the second and third molar sites were marked as Group C (<i>n</i> = 134), and the remaining sites were marked as Group D (<i>n</i> = 214).</p><p><strong>Results: </strong>The RBH before implant placement was 6.63 ± 2.10 mm (95% confidence interval [CI] 6.41- 6.85 mm). The mucosal EH was 4.04 ± 1.86 mm (95% CI 3.85 - 4.24 mm). The NH was 2.36 ± 1.20 mm (95% CI 3.85-4.24 mm). No other complications were found except three cases of postoperative swelling and one case of nasal blood secretions. The overall mucosal perforation rate was 1.44% (5/348, 95% CI 0.2%-2.7%) and the rate of RBH ≤ 5 mm (Group A) was 1.49% (2/134, 95% CI 0%-3.50%). The 8-year CSR was 99.71% (347/348, 95% CI 99.2%-100.0%). Mucosal EH and NH were higher in RBH ≤5 mm (Group A) than in RBH >5 mm (Group B) (<i>P</i> = 0.001 and <i>P</i> = 0.001, Mann-Whitney <i>U</i>-test). There were no significant differences in mucosal EH and perforation rate between second and third molar sites (Group C) and other sites (Group D) (<i>P</i> = 0.77, Mann-Whitney <i>U</i>-test, and <i>P</i> = 0.16, Yates' Chi-square independence test).</p><p><strong>Conclusions: </strong>CSA-HBP is a minimally invasive and reliable technique.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 4","pages":"428-433"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10049995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V Vasanthi, Tamizh Paavai Tha, A Ramesh Kumar, Sasikala Balasubramanian
{"title":"Paradental cyst with hyaline ring granuloma masquerading as pericoronitis.","authors":"V Vasanthi, Tamizh Paavai Tha, A Ramesh Kumar, Sasikala Balasubramanian","doi":"10.4103/jisp.jisp_292_22","DOIUrl":"10.4103/jisp.jisp_292_22","url":null,"abstract":"<p><p>Paradental cyst is an odontogenic cyst associated with pericoronitis in partly erupted mandibular third molars. It is an inflammatory cyst common among the mandibular molars. The cyst is most commonly seen on the distal or distobuccal aspect of the third molars. The angle of tooth and food impaction has been postulated to be responsible for the development of the cyst in third molars. The source of the epithelium has been reported as reduced enamel epithelium. The paradental cyst is frequently misdiagnosed as a radicular cyst or dentigerous cyst. We report a case of paradental cyst in a patient with partially erupted mandibular third molar with food impaction and resulting hyaline ring granuloma.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 4","pages":"434-436"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431234/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10049998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ethics in publication: Some life lessons.","authors":"Harpreet Singh Grover","doi":"10.4103/jisp.jisp_250_23","DOIUrl":"10.4103/jisp.jisp_250_23","url":null,"abstract":"","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 4","pages":"342-343"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10022108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"<i>In vitro</i> evaluation of remineralizing agents on dentinal tubule occlusion: A scanning electron microscopic study.","authors":"Akanksha Kidiyur Sathish, Pratibha Gopalkrishna, Santhosh Kumar","doi":"10.4103/jisp.jisp_413_22","DOIUrl":"10.4103/jisp.jisp_413_22","url":null,"abstract":"<p><strong>Context: </strong>Over the years, numerous treatment modalities have been researched for the management of dentinal hypersensitivity. A recent remineralizing agent containing a phase of amorphous calcium phosphate combined with fluoride has shown the ability to rapidly convert into biomimetic hydroxyapatite. This potential can be utilized in occluding the dentinal tubules for the treatment of hypersensitivity.</p><p><strong>Aims: </strong>The present study aims to compare the effectiveness of biomimetic hydroxyapatite-based tooth mousse and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) tooth mousse as desensitizing agents on dentinal tubule occlusion.</p><p><strong>Materials and methods: </strong>The <i>in vitro</i> study design involved 30 prepared dentin specimens that were divided into three groups: Group A: negative control, Group B: CPP-ACP tooth mousse (GC tooth mousse<sup>™</sup>), and Group C: fluoride-doped amorphous calcium phosphate (F-ACP) tooth mousse (Curasept Biosmalto Denti Sensibili Tooth Mousse). The specimens were observed under a scanning electron microscope (SEM) and an attached energy-dispersive X-ray (EDX) spectroscopy apparatus after 1 week.</p><p><strong>Statistical analysis: </strong>The data were analyzed using Kruskal-Wallis test and <i>post hoc</i> Mann-Whitney test for intragroup and intergroup analysis, respectively.</p><p><strong>Results: </strong>The SEM analysis of the F-ACP group showed statistically greater percentage of tubule occlusion (40.21%) compared to the CPP-ACP group (38.15%). EDX analysis of both F-ACP and CPP-ACP groups revealed calcium, phosphorus, carbon, oxygen, and silica with an additional fluoride element in the F-ACP group.</p><p><strong>Conclusions: </strong>In the present study, both remineralizing agents were able to occlude the dentinal tubules. Among the two, the F-ACP tooth mousse showed greater tubule occlusion, and therefore, appears promising as an upcoming remineralizing agent in the management of dentinal hypersensitivity.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 4","pages":"362-367"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10038266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R P Meenakshi, R Kiruba, K V Arun, G Sivaram, Deepavalli Arumuganainar, K Kaveri
{"title":"Cell-based therapy in the management of Class III Miller's recession - A case report with 45-month follow-up.","authors":"R P Meenakshi, R Kiruba, K V Arun, G Sivaram, Deepavalli Arumuganainar, K Kaveri","doi":"10.4103/jisp.jisp_436_22","DOIUrl":"10.4103/jisp.jisp_436_22","url":null,"abstract":"<p><p>Miller's Class III gingival recessions (GRs) have always posed a challenge to the clinicians in terms of achieving complete root coverage (CRC). In the present case, a cell-based therapy with autologous fibroblasts seeded onto a Type 1 collagen membrane, through an <i>in-vitro</i> culturing method was utilized. The fibroblasts-seeded membrane was surgically placed under a laterally repositioned flap. The patient presented with a CRC, which was stable even at the postoperative period of 45 months. In addition, a 3-mm substantial gain in the width of keratinized tissue was achieved and maintained throughout the postoperative period. Hence, the results of the cell-seeded therapy emphasize that it can serve as an effective alternative method for the management of Miller's Class III GRs.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 4","pages":"437-442"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10049994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}